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MedicYatra provides the safe & best Infertility treatment at its affiliate & trusted hospitals & clinics in various metro cities of India, like Mumbai, Delhi, Bangalore, Chennai, Pune etc.Our Associate Board certified doctors are extensively trained and vastly experienced and have performed hundreds of such cases at our state of the art JCI accredited hospitals & Clinics. Our aim is to provide you the best of the services at the most affordable costs. Don't forget to say hi at [email protected]
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Infertility facts affects 1 in 6 married couples of
childbearing age definition: have engaged in unprotected
coitus for 1 year and haven’t become pregnant
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Infertility Facts can be due to:
– failure to conceive, loss of conceptus origin of problem:
– 35% female– 35% male– 20% both partners– 10% unexplained
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Failure to ovulate
often caused by low body fat or stress GnRH surge may be inadequate
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Tubal blockage Due to:
– Endometriosis, scar tissue from STD, previous surgery
Treatment: surgery If surgery unsuccessful, IVF, GIFT and
ZIFT are best options
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Causes of male infertility low sperm count (oligospermia) or
absence of sperm (azoospermia) male may produce antibodies to his own
sperm accessory glands / ducts may
malfunction
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Intracervical or intrauterine insemination (ICI / IUI) Artificial insemination definition: sperm introduced into female
reproductive tract by means other than coitus (near cervix or in uterus)
sperm can come from donor / sperm bank or from husband
Example of a sperm bank:– http://www.spermbankcalifornia.com/buy-sp
erm-online.html
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ICI / IUI, cont’d.
usually, several ejaculations are pooled 60,000 babies / year born in US. as
result of artificial insemination often used when male has low sperm
count or antibodies present in ejaculate
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In vitro fertilization
“test - tube babies” 1st performed in 1978 (Louise Joy
Brown) often performed on infertile women with
tubal blockage
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IVF Protocol GnRH agonist (e.g. Lupron) for 7 days FSH agonist (follistim, Gonal-F,
Repronex) until follicles measure 17-20 mm in diameter (8-14 days)
hCG given to induce egg maturation Egg retrieval (transvaginally) 34-35 h
later
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IVF protocol sperm and ova added to dish;
fertilization occurs 12-14hrs. eggs transferred to new dish and cell
division occurs embryos squirted into uterus (optimal
stage: blastocyst) Preimplantation genetic diagnosis (PGD)
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IVF Protocol, cont’d. 3 to 5 embryos are injected to increase
chances of pregnancy woman given progestagen to prevent
miscarriage Example of prices:
– http://www.advancedfertility.com/ivfprice.htm
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IVF Protocol, cont’d. new variations / improvements:
– Intracytoplasmic sperm injection (ICSI)– use of frozen embryos
27,000 attempts made per year; 18.6% successful (success rates are increasing)
http://www.advancedfertility.com/sampleivfcalendar.htm
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IVF, cont’d.
Ethical questions:– will it lead to selective breeding?– up to what stage can research be done?– if embryo dies in vitro, is it abortion, murder?– what should be done w/ unwanted embryos?– should government regulate research?
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GIFT and ZIFT GIFT = gamete intrafallopian transfer useful for tubal blockage ova are collected and inserted into
oviducts below point of blockage husband’s sperm are placed in oviduct
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GIFT and ZIFT woman is treated with hormones to prevent
miscarriage 28% successful ZIFT = zygote intrafallopian transfer ZIFT is like IVF, only zygotes (1 cell stage)
are inserted below blockage in oviduct (24% success rate)
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Others
Ovarian stimulation protocol Surrogate pregnancy Adoption
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