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1 Nanosonics Limited | Annual General Meeting 2021 Infection Prevention. For Life. 2021 ANNUAL GENERAL MEETING

Infection Prevention. For Life

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Page 1: Infection Prevention. For Life

1Nanosonics Limited | Annual General Meeting 2021

Infection Prevention.For Life.

2021ANNUAL GENERALMEETING

Page 2: Infection Prevention. For Life

2Nanosonics Limited | Annual General Meeting 2021

A C K N O W L E D G E M E N T O F C O U N T R Y

We acknowledge the traditional owners of the various lands in which we meet virtually today and

pay respects to all Aboriginal Elders, past and present, and acknowledge today’s Aboriginal

communities who are the custodians of these lands.

Page 3: Infection Prevention. For Life

3Nanosonics Limited | Annual General Meeting 2021

B O A R D O F D I R E C T O R S

Geoff WilsonNon-Executive Director

Maurie StangNon-Executive Chairman

David FisherNon-Executive Director

Marie McDonaldNon-Executive Director

Lisa McIntyreNon-Executive Director

Steven SargentNon-Executive Director, Deputy Chairman and Lead Independent Director

Michael KavanaghCEO and President

Page 4: Infection Prevention. For Life

4Nanosonics Limited | Annual General Meeting 2021

O N L I N E A T T E N D E E S – Q U E S T I O N P R O C E S S

When the Question function is available, the Q&A icon will appear at the top of the app.

To send in a question, simply click in the ‘Ask a question’ box, type your question and the press the send arrow

Your question will be sent immediately for review

Page 5: Infection Prevention. For Life

5Nanosonics Limited | Annual General Meeting 2021

O N L I N E A T T E N D E E S – V O T I N G P R O C E S S

When the poll is open, the vote will be accessible by selecting the voting icon at the top of the screen

To vote simply select the direction in which you would like to cast your vote, the selected option will change colour.

There is no submit or send button, your selection is automatically recorded.

Page 6: Infection Prevention. For Life

6Nanosonics Limited | Annual General Meeting 2021

Infection Prevention.For Life.

CHAIRMAN’S ADDRESSMaurie Stang, Chairman

2021ANNUAL GENERALMEETING

Page 7: Infection Prevention. For Life

7Nanosonics Limited | Annual General Meeting 2021

Our people,our advantage

1Compound Annual Growth Rate2Science, Technology, Engineering, Mathematics

94% STRONGLY AL IGNED TO COMPANY PURPOSE

93% KNOW HOW THE IR WORK CONTR IBUTES TO COMPANY GOALS

339 TOTAL EMPLOYEESEND ING FY21(+9% VS . FY20 )

Page 8: Infection Prevention. For Life

8Nanosonics Limited | Annual General Meeting 2021

G R O W I N G O P P O R T U N I T I E S

8Nanosonics Limited | Annual General Meeting 2021

NANOSONICS AUDITPROTM

Launched new digital product platform delivering a unique new digital workflow compliance management system.

NEXT TECHNOLOGY PLATFORM – CORIS®

Advanced our next infection prevention technology platform focussed on one of the most significant issues in instrument reprocessing today – flexible endoscope cleaning.

M A R K E T S

INCREASED TAM IN NORTH AMERICA50% growth in trophon TAM (to 60,000 units), driven by strong ultrasound growth.

IMPROVING FUNDAMENTALS FOR ADOPTION IN EMEAIncrease in guidelines and associated Nanosonics investment in the region.

EXPANDING OUR BUSINESS IN ASIA PACIFICStrengthening fundamentals in Japan, and established local presence in China.

P R O D U C T S

INVESTMENTS IN INNOVATIONContinued investments in product expansion strategy with $17.2 million in R&D directed across multiple projects.

Driving trophon® business growth

Page 9: Infection Prevention. For Life

9Nanosonics Limited | Annual General Meeting 2021

F I V E C O R E A R E A S O F R & D F O C U S

All research and new product development programs involve inherent risks and uncertainties which can impact commercialisation timelines.

$9.5 $9.9$11.4

$15.6

$17.2

FY17 FY18 FY19 FY20 FY21

11% vs. FY20

INVESTMENT IN R&DGlobal, $m

Core R&D

Sustaining engineering

External technology evaluation

Nanosonics Investments

STRATEGIC CAPABIL IT IES

9Nanosonics Limited | Annual General Meeting 2021

Page 10: Infection Prevention. For Life

10Nanosonics Limited | Annual General Meeting 2021

We value all aspects of diversity fostering an

inclusive workplace for all to fulfil their

potential.

~29N A T I O N A L I T I E SR E P R E S E N T E D

41%F E M A L EG E N D E R R A T I O

42%F E M A L E S I NS T E M 2 R O L E S

14I N T E R N S / G R A D U A T E P R O G R A M S

1For full details, refer to the Nanosonics 2021 Sustainability Report2Science, Technology, Engineering, Mathematics3National Greenhouse Accounts Factors (NGAF)

SUSTAINABILITY HIGHLIGHTS1

Introduced Executive Risk Management Committee

Developed sustainable Supply Chain initiatives

Strengthened IT, Privacy & Cybersecurity protections

Patients protected daily from the risk of cross-contamination~88k

C O N T I N U E D C O M M I T M E N T T O S U S T A I N A B I L I T Y A N D S O C I A L R E S P O N S I B I L I T Y

Zero major work health and safety incidents

CONTINUED ENVIRONMENTAL COMMITMENT

~$44k in funds raised through charitable initiatives

DIVERSITY & INCLUSION

Page 11: Infection Prevention. For Life

11Nanosonics Limited | Annual General Meeting 2021

L E A D E R S H I P

M A U RI ES T A NG

S T E V E NS A RG E NT

M I C H A E LK A V ANAG H

M A R I EM C D O N ALD

D A V I DF I S H E R

L I S AM C I N T Y RE

G E O F FW I L S O N

BOARD OF DIRECTORS

EXECUTIVE TEAM

M I C H A E LK A V ANAG H

M C G R E G O RG R A N T

K E NS H AW

R O N A NW R I G H T

D A V I DM O R R I S

R E N E ES A LABERRY

S T E V E NF A R RUG I A

R O DL O P E Z

J O D IS A M PSO N

Nanosonics has a highly experienced and dedicated team of professionals leading the development and implementation of our strategic growth agenda.

Page 12: Infection Prevention. For Life

12Nanosonics Limited | Annual General Meeting 2021

Infection Prevention.For Life.

2021ANNUAL GENERALMEETING

CEO & PRESIDENT’S ADDRESSMichael Kavanagh, CEO and President

Page 13: Infection Prevention. For Life

13Nanosonics Limited | Annual General Meeting 2021

F Y 2 1 K E Y H I G H L I G H T S

26,75013%

$103.1m $26.7m $76.4m

3% (12% cc1

)11% (8% cc1

) 9% (20% cc1

)

INSTALLED BASE TOTAL REVENUE CAPITAL REVENUECONSUMABLES/

SERVICE REVENUE

1Constant currency removes the impact of foreign exchange rate movements to facilitate comparability of operational performance. This is done byconverting the current year sales of entities that use currencies other than Australian dollars at the average rates that were applicable in the prior year.

A year of ongoing achievement with a significant recovery in H2to pre-COVID growth momentum levels

13Nanosonics Limited | Annual General Meeting 2021

20% v s . H 1 v s . H 1 v s . H 1 v s . H 139% 84% 27%

$60.0m $17.3m $42.7m

FY21

H2

Page 14: Infection Prevention. For Life

14Nanosonics Limited | Annual General Meeting 2021

TROPHON AS STANDARDOF CARE

EXPAND GEOGRAPHIC

FOOTPRINT

PRODUCT EXPANSION

INVESTTO GROW

OURSTRATEGICPRIORITIES

Support establishment of national guidelines.

Provide awareness and education to highlight risks of cross contamination for all semi critical transducers.

Ensure Customers have a positive experience with all aspects of the product and brand.

Expand operations across Asia Pacific &

EMEA with trophon plus new products.

Expand portfolio of infection prevention solutions to address unmet needs.

Maintain strong financial position to support growth.

Deliver operational efficiencies, scale and leverage.

Leverage technology platforms for potential expanded indications.

Strategic acquisitions in the infection prevention space.

14Nanosonics Limited | Annual General Meeting 2021

“Nanosonics’ forward-looking growth agenda

remains very much intact with significant

opportunities for growth of the trophon

franchise as well as significant

opportunities from the planned expanded product portfolio.”

- Michael Kavanagh

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15Nanosonics Limited | Annual General Meeting 2021 15Nanosonics Limited | Annual General Meeting 2021

TROPHON®

OPPORTUNITY

Page 16: Infection Prevention. For Life

16Nanosonics Limited | Annual General Meeting 2021

U L T R A S O U N D P R O C E D U R E S

There are over 150 procedures1 that use ultrasound probes across many departments that risk contact with mucous membranes, non-intact skin and/or sterile tissue.

E X A M P L E S

UG 2 BIOPSY NERVE BLOCKSINTRAOPERATIVE WOUNDS

+ AND MANY MORE. . .

ENDOCAVITARY

Abdominal Duplex Vascular (complete & limited, transvaginal)

Pregnancy scans

Chorionic Villus Sampling

Transrectal scan

Transrectal prostate biopsy

Biopsy of liver

Biopsy of pancreas

Biopsy of pleural fluid

Biopsy of pulmonary lesions

Biopsy of salivary gland

Biopsy of sclerosing mesenteritis

Intraoperative neurosurgical procedures

Intraoperative UG tracer injection

UG implantation of iodine seeds

UG percutaneous renal transplant biopsy

UG transthoracic punctures

UG cervical nerve root block

UG ankle block

UG femoral nerve block

UG ophthalmic regional anesthesia

UG percutaneous peripheral nerve

stimulation

UG burn patient assessment

UG Focused Assessment with Sonography in

Trauma (FAST)

UG focused diagnostic echocardiography (e.g., cardiac resuscitation in presence of trauma)

1Nanosonics analysis, SDMS guidelines, market reports 2Ultrasound-guided 16Nanosonics Limited | Annual General Meeting 2021

Page 17: Infection Prevention. For Life

17Nanosonics Limited | Annual General Meeting 2021

N O R T H A M E R I C A

There has been a significant increase in the trophon®

opportunity in North America resulting from increased estimate of Total Addressable Market, revised up to 60,0001 units from 40,000 units, reflecting growth in the ultrasound market over the last eight years.

60,0001

39%

12,400

15,620

18,570 20,990

23,480

FY17 FY18 FY19 FY20 FY21

150k

ULTRASOUND INSTALLED BASE

U N I T E D S T A T E S

271k1

40,000UNITS

60,0001

UNITS

TROPHON TAMNORTH AMERICA2

P R I O RE S T I M ATE

R E V I SEDE S T I M ATE

A detailed analysis of the U.S. Ultrasound

market has revealed that the total market

opportunity for trophon is 50% larger

than previous estimates.

2Total Addressable Market updates to U.S. only.

UNITS

INSTALLED BASEINSTALLED BASE OPPORTUNITY

MARKET PENETRATION

1Nanosonics analysis based on updated ultrasound information commissioned by Nanosonics and an estimated trophon to ultrasound attachment rate. The North America market has been the focus of the TAM analysis undertaken.

Page 18: Infection Prevention. For Life

18Nanosonics Limited | Annual General Meeting 2021

S I G N I F I C A N T G L O B A L M A R K E T O P P O R T U N I T Y

GLOBAL Installed base opportunity

140,0001

UNITS

• Significant global growth opportunity.

• Increasing number of international guidelines requiring high level disinfection (HLD) supporting growing international demand.

• Nanosonics expanding its footprint geographically both direct and through distribution.

19%

Market Penetration

INSTALLED BASE

N O R T H A M E R I C A

Strong Fundamentals• Fundamentals for adoption strong with requirements for HLD in

place.

• trophon installed base over 23,480 and already in over 5,000 hospitals and clinics, including majority of luminary hospitals.

• Nanosonics has a direct sales operation of 74 people as well as partnerships with all leading ultrasound companies to drive ongoing adoption.

Installed Base Opportunity

UNITS 39%

12,400 15,620

18,570 20,990

23,480

FY17 FY18 FY19 FY20 FY21

INSTALLED BASE

E U R O P E A N D M I D D L E E A S T

Strengthening Fundamentals• Expanded geographical reach, strengthening fundamentals for

adoption and growing awareness.

• Expanded infrastructure with sales teams increasing in the UK and Germany, plus appointment of local clinical, marketing, regulatory, service, distributor partner engagement & people and culture leadership.

• A range of business models In place to support market requirements.

UNITS

Installed Base Opportunity

4%

16%

UK

490 730

880 1,120

1,510

FY17 FY18 FY19 FY20 FY21

INSTALLED BASE

A S I A P A C I F I C

Strengthening Fundamentals• Sales mainly in ANZ where market penetration is >75%.

• Japan market development strategy continues with local infrastructure established & distribution agreements in place with five key distributors.

• Finalised registration of a wholly owned subsidiary in China with regulatory submission being prepared.

• Assessment underway for further expansion across Asia Pacific.

UNITS

Installed Base Opportunity

4%

>75%

ANZ

1,270 1,390

1,480 1,610

1,760

FY17 FY18 FY19 FY20 FY21

1Nanosonics analysis based on updated ultrasound information commissioned by Nanosonics and an estimated trophon to ultrasound attachment rate.

Market Penetration Market Penetration Market Penetration

2Based on Nanosonics’ estimate from around 2011. While current data is not readily available for the Asia Pacific and Europe and Middle East regions, the Company considers that the ultrasound market has grown in these regions since the initial estimate of the Installed Base Opportunity was made.

60,0001 40,0002 40,0002

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19Nanosonics Limited | Annual General Meeting 2021

9%

7%6%

2%

1 yr 2 yrs 3 yrs 4 yrs 5 yrs 6 yrs 7 yrs 8 yrs 9 yrs 10+ yrs

6,500+ units

C A P I T A L U P G R A D E S

G L O B A L I N S T A L L E D B A S E A G E D I S T R I B U T I O N A T J U N 2 0 2 1

GROWING OPPORTUNITY

Implemented trophon EPR end-of-life policies and notified

customers.

Upgrades is a key component of growth strategy for FY22.

A significant capital upgrade potential exists in the

installed base

AGED INSTALLED BASEUPGRADED TO-DATE1 8%

1 Upgrades as a % of cumulative Installed Base 7 years or older

Page 20: Infection Prevention. For Life

20Nanosonics Limited | Annual General Meeting 2021

E U R O P E A N D M I D D L E E A S T

40,000

490 730

880 1,120

1,510

FY17 FY18 FY19 FY20 FY21

Guidelines across Europe for ultrasound probe disinfection continue to strengthen with preferences for automated solutions that can be validated. This has supported installed base growth with significant ongoing growth potential.

4% 16%

UK

U L T R A S O U N D R E P R O C E S S I N G

G U I D E L I N E S

UNITS

INSTALLED BASEINSTALLED BASE OPPORTUNITY

MARKET PENETRATION

| Annual General Meeting 2021

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21Nanosonics Limited | Annual General Meeting 2021

2016 2021

N A N O S O N I C S P R E S E N C E I N E U R O P E A N D M I D D L E E A S T

We have broad presence and access to key markets to capitaliseon the strengthening fundamentals across the region.

S W E D EN

N O RWA Y

D E N M A RK

U N IT ED K I NGDOM

I R E LA ND

F R A NCE

G E RM A NY

S P A IN

P O RT UGAL

S W I TZ ERLA ND

B E LG IUM

A U S TR IA

F I N LA ND

E S TO NIA

R U SS IA

EMEA EMPLOYEESHeadcount, 2016-2021

38% CAGR

MARKET ACCESS THROUGH DIRECT AND DISTRIBUTION CHANNELS

N E T H ERLANDS

I T A LY

INVESTING FOR GROWTH

Page 22: Infection Prevention. For Life

22Nanosonics Limited | Annual General Meeting 2021

A S I A P A C I F I C

1,270 1,390

1,480 1,610

1,760

FY17 FY18 FY19 FY20 FY21

We have ramped up our efforts to bring new markets online, with particular focus on the untapped potential in Japan, China and across the ASEAN countries.

The trophon technology is the standard of care in Australia and New Zealand• Launched the trophon2 upgrade program with I-MED upgrading 200 trophon EPRs.

• Delivered education programs demonstrating the importance and requirements for high level disinfection for semi-critical probes in accordance with standards and guidelines.

• Continued to invest in our capabilities establishing an ANZ Customer Service Centre, including Clinical Application Specialists to ensure seamless and consistent Customer and Distributor experience.

Built a solid foundation this year, as we work towards establishing local guidelines• Conducted virtual education and training with relevant specialists, societies and distributors

• Continued to develop strong relationships with the ultrasound OEMs as distributors of trophon in Japan, as well as many sub-distributors.

• Continue to build our direct team to drive market awareness and support our distributor partners.

Finalised Registration of Wholly Owned Foreign Enterprise (WOFE) 纳安诺医疗设备(上海)有限公司(translated to Nanosonics Medical Device (Shanghai) Co. Ltd.).

• Developing regulatory strategy.

• Appointed qualified local consultant in China to manage all local activity required for market entry.

Received regulatory approval in Malaysia, Indonesia, Thailand and the Philippines• Continued execution of our market entry strategy for ASEAN (Indonesia, Thailand, Malaysia, Philippines, Vietnam).

ANZ

JAPAN

CHINA

ASEAN

4% >75%

ANZ

40,000INSTALLED BASEINSTALLED BASE OPPORTUNITY

MARKET PENETRATION

UNITS

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23Nanosonics Limited | Annual General Meeting 2021 23Nanosonics Limited | Annual General Meeting 2021

INVESTING FOR GROWTHRESEARCH & DEVELOPMENT

Page 24: Infection Prevention. For Life

24Nanosonics Limited | Annual General Meeting 2021

Substantial investment made in new product development with

important milestones met throughout the year towards our

product expansion goals.

N E W P R O D U C T D E V E L O P M E N T

24Nanosonics Limited | Annual General Meeting 2021

During the year, Nanosonics

continued to invest in its product

expansion strategy. R&D investment

increased to

$17.2mdirected across

multiple projects.

9.5 9.9

11.4

15.6

17.2

FY17 FY18 FY19 FY20 FY21

11% vs. FY20

INVESTMENT IN R&DGlobal, $m

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25Nanosonics Limited | Annual General Meeting 2021

I N T R O D U C I N G

25Nanosonics Limited | Annual General Meeting 2021

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26Nanosonics Limited | Annual General Meeting 2021 26Nanosonics Limited | Annual General Meeting 2021

Asset utilization and management overview

Provides probe utilization dashboards so probe location and usage patterns can be tracked and

compliance spot-checked.

INFECTION CONTROL WORKFLOW COMPLIANCE MANAGEMENT

Practice standardizationStandardises ultrasound infection control compliance practices to improve risk management and quality control, delivering best practice.

Supports accreditationStreamlines your organisation’s compliance with National standards and evidence-based guidelines. It provides you with real-time risk notifications for easy course-correction and survey-ready ultrasound infection prevention compliance reports.

Compliance educationUniquely sits with the ultrasound console at point of use, educating the user and enabling consistent incorporation of infection control considerations, as part of everyday clinician care.

Global best practiceSupports optimal patient care across your organisation by standardising best practice infection prevention decisions and managing staff compliance to Spaulding classification and your standard operating procedures (SOPs).

Enhances clinical workflowImproves staff competency with the Spaulding

Classification, reprocessing activities and probe usage. On-the-job education is built into everyday workflow.

Timely remediation and risk-minimization

Automated email notifications highlight non-compliance events for rapid risk assessment that

enhances risk management for improved patient care.

Digitised traceability and record management

Intuitive and information-rich dashboards providing actionable insights on infection control practices.

Generates digital logbooks to help reduce operating costs and improve track and trace accuracy.

26Nanosonics Limited | Annual General Meeting 2021

Workflow compliance management tool that ensures customers consider the infection prevention requirements for all ultrasound procedures

DATA-LED INFECTIONPREVENTION INSIGHTS

INFECTION CONTROLAT POINT-OF-CARE

Spaulding Patient MRN Probe

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27Nanosonics Limited | Annual General Meeting 2021

A U D I T P R O A N D T R O P H O N S Y N E R G I E S

trophon2 adoption

AuditPro further enhances the trophon2 value proposition and competitive advantage.

EPR to trophon2 upgrades

Consumables usage

N A N O S O N I C S A U D I T P R O T M

H A S T H E P O T E N T I A L T O D R I V E …

Page 28: Infection Prevention. For Life

28Nanosonics Limited | Annual General Meeting 2021 28Nanosonics Limited | Annual General Meeting 2021

OUR NEXT INSTRUMENT REPROCESSING PRODUCT

PLATFORM

All research and new product development programs involve inherent

risks and uncertainties which can impact commercialisation timelines.

Page 29: Infection Prevention. For Life

29Nanosonics Limited | Annual General Meeting 2021

“more healthcare-associated outbreaks have been linked to contaminated endoscopes than to any other medical device”

U.S. Center for Disease Control (CDC)1

O U R N E W P R O D U C T P L A T F O R M F O C U S

In 2018, the ECRI Institute listed “failure to consistently and effectively reprocess flexible endoscopes” as one

of the top 10 health technology hazards facing the Healthcare industry. In particular, the Institute drew attention

to “The cleaning step, which is largely manual and technique-dependent. If biologic debris and other foreign

material is not cleaned from the endoscope first, residual soil can harden, making subsequent disinfection ineffective.”

– ECRI Institute, 20182

AUTOMATED ENDOSCOPE CLEANINGThe Nanosonics team have focussed on the complex technical challenges of flexible endoscope cleaning with the aim of developing a novel automated technology designed to revolutionise the cleaning process of flexible endoscopes.

A TOP 10 HEALTH TECH N OLOGY HAZARD

NANOSONICSCORIS®

1Guideline for Disinfection and Sterilization in Healthcare Facilities, U.S. CDC. Update: May 2019.2Top 10 Health Technology Hazards for 2018, ECRI Institute, 2018.

Transforming the cleaning of flexible endoscopes

All research and new product development programs involve inherent risks and uncertainties which can impact commercialisation timelines.

Page 30: Infection Prevention. For Life

30Nanosonics Limited | Annual General Meeting 2021

MANY SCOPE DESIGNS AND MODELS FOR A LARGE VARIETY OF COMPLEX CLINICAL PROCEDURES

F L E X I B L E E N D O S C O P E S

GASTROSCOPY E.N.T.UROLOGYENDOSCOPICULTRASOUND

BRONCHOSCOPY GYNAECOLOGYENTEROSCOPYE.R.C.P.COLONOSCOPY

Reusable flexible endoscopes are highly sophisticated medical devices designed to enable advanced diagnostic and therapeutic interventions to

diagnose and treat cancers and other life-threatening conditions. They incorporate advanced technology that gives physicians a sophisticated level of control in

carrying out complex, minimally-invasive procedures and navigating challenging anatomical situations to deliver the highest level of patient care.

MAJOR DRIVERS

Aging population

Increasing incidence of colorectal cancer

Various national-level screening programs

>60m+ 6%

ANNUALPROCEDURES

ANNUALGROWTH RATE

FLEXIBLE ENDOSCOPY MARKET1

US, EU-5 , AU

1Frost & Sullivan, Endoscope Reprocessing Systems and Software Solutions Market Assessment (US, W. Europe, Australia), 2018.All research and new product development programs involve inherent risks and uncertainties which can impact commercialisation timelines.

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31Nanosonics Limited | Annual General Meeting 2021

A R E C O G N I S E D R I S K

Flexible endoscopes have been associated with a high frequency of outbreaks of healthcare-associated infections.

…AND REPROCESSING ISSUESINFECTION OUTBREAKS…

E.R.C.P.

UROLOGICAL SCOPES

GASTROSCOPES

BRONCHOSCOPES

COLONOSCOPES

BIOF ILM

HUMAN FACTORS

. . .

REPROCESSING FA ILURE

…ACROSS MANY SCOPE TYPES INDICATING A SIGNIFICANT UNMET NEED WITH CURRENT METHODS.

THERE ARE MANY WELL-DOCUMENTED INSTANCES OF…

All research and new product development programs involve inherent risks and uncertainties which can impact commercialisation timelines.

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32Nanosonics Limited | Annual General Meeting 2021

HUMAN FACTORSManual cleaning involves 55 to 200 individual steps,

including brushing and flushing.

BIOFILMBiofilm was detected in 83% of air/water channel

components after 30-60 days of use1. Biofilm protects embedded microbes from HLD and requires physical

cleaning methods to effectively be removed from channels.

SOPHIST ICATED DESIGNIntricate internal architecture has multiple

interconnected channels with complex ports.

NARROW CHANNELSMany channels are so narrow or geometrically

complex (e.g. air and water) that they are physically impossible to brush today.

Up to

9channel

openings

T H E P R O B L E M O F C L E A N I N G F L E X I B L E E N D O S C O P E S

Challenges associated with manual cleaning, combined with reports of persistent contamination from biofilm despite routine cleaning, represents a significant unmet need and is a complex technical

challenge that has existed for many years.

A IRCHANNEL1

A IR /WATERCHANNEL2

A IR /WATERJUNCT ION 1

WATERCHANNEL1

2Pajkos, A., et al., 2004. Is biofilm accumulation on endoscope tubing a contributor to the failure of cleaning & decontamination? Journal of Hospital Infection.

SUCT ION/B IOPSYCHANNEL2

Up to

200steps

32Nanosonics Limited | Annual General Meeting 2021

Down to

1mm

In diameter

A 2021 study on gastroscopes revealed that extensive biofilm accumulatedin the majority of air and water channels within 30 days of clinical use

despite routine cleaning.1

1Primo, M.G.B., et al., 2021. Biofilm accumulation in new flexible gastroscope channels in clinical use. Infection Control & Hospital Epidemiology.

Up to

83%

All research and new product development programs involve inherent risks and uncertainties which can impact commercialisation timelines.

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33Nanosonics Limited | Annual General Meeting 2021

Nanosonics aims to address these challenges by replacing manual cleaning of endoscope channels with a novel automated technology that revolutionises the cleaning process, thereby reducing the risk of ineffective endoscope reprocessing and resulting patient infection.Work continues to progress positively with the product development including the integration of a number of enhancements to the new platform. This work will be followed by external clinical assessment to support the regulatory submission. Nanosonics continues to engage with the US FDA to determine the necessary requirements to support a successful regulatory submission. The timing for commercial launch previously indicated is being revised and will be determined in due course dependent on the necessary technical, regulatory and operational milestones being met with the Company currently targeting the first commercial launch to occur in calendar 2023. Updates will be provided as material new information becomes available. The Company remains confident both in the ongoing progress of the development project, and importantly in the overall commercial opportunity for this transformational technology platform which it believes has the potential to become a new standard of care for endoscope cleaning.

NANOSONICS CORIS®

All research and new product development programs involve inherent risks and uncertainties which can impact commercialisation timelines.

Page 34: Infection Prevention. For Life

34Nanosonics Limited | Annual General Meeting 2021

“Despite the inherent risks and uncertainties associated with COVID-19, we remain optimistic the improved market conditions will continue as

vaccination numbers increase across all major markets.”– Michael Kavanagh

FY22 BUSINESS OUTLOOK

DOUBLE DIGIT REVENUE GROWTHIncreasing global installed base

Increasing consumables usage across all regionsGrowth in EPR to trophon2 upgrades

>75%

$90m

GROSS PROFIT MARGINIncreasing capital (new IB and upgrades) in revenue mix

OPERATING EXPENSESContinued investment in our long-term strategic growth agenda

BEYOND FY22

TROPHON BUSINESS GROWTHGlobal expansion of Trophon installed base and associated ecosystem

Increasing upgrade momentum and conversions to trophon2Critical new markets brought online, including Japan and China

LEADERSHIP IN INFECTION PREVENTIONOngoing investment in R&D, infrastructure, people and

capabilities to drive our global growth strategy

NEW SOURCES OF REVENUELaunch of Nanosonics AuditProTM to new markets

Further new product launches

INVESTMENT IN INNOVATIONExpanded product portfolio through internal product development and R&D

Opportunities for strategic acquisitions and product licensing

34Nanosonics Limited | Annual General Meeting 2021

(assuming the positive market recovery trends continue)

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35Nanosonics Limited | Annual General Meeting 2021

Infection Prevention.For Life.

2021ANNUAL GENERALMEETING

FORMAL BUSINESS

Page 36: Infection Prevention. For Life

36Nanosonics Limited | Annual General Meeting 2021

Resolution: That Dr. David Fisher, who retires as a Director pursuant to the Company’s Constitution and, being eligible, offers himself for re-election, be re-elected a Director.

R E S O L U T I O N 1

Re-election of a director – Dr. David Fisher

Proxy votes received Number %

For : 170,167,164 97.72

Against : 3,279,127 1.88

Discretion : 682,973 0.40

Abstained/Excluded : 300,476 -

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37Nanosonics Limited | Annual General Meeting 2021

R E S O L U T I O N 2

Re-election of a director – Mr. Geoff Wilson

Proxy votes received Number %

For : 170,818,924 98.11

Against : 2,598,880 1.49

Discretion : 682,973 0.40

Abstained/Excluded : 328,963 -

Resolution: That Mr. Geoff Wilson, who retires as a Director pursuant to the Company’s Constitution and, being eligible, offers himself for re-election, be re-elected a Director.

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38Nanosonics Limited | Annual General Meeting 2021

Resolution: That the Remuneration Report for the financial year ended 30 June 2021 be adopted.

R E S O L U T I O N 3

Remuneration Report

Proxy votes received Number %

For : 156,359,607 95.41

Against : 4,646,030 2.83

Discretion : 2,880,078 1.76

Abstained/Excluded : 10,544,025 -

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39Nanosonics Limited | Annual General Meeting 2021

Resolution: That approval be given for all purposes under the Corporations Act 2001 (Cth) and the ASX Listing Rule 10.14 for the issue of 30,010 Service Rights to Mr Michael Kavanagh under the Nanosonics Omnibus Equity Plan (Omnibus Plan) in respect of the 2021 STI, on the terms set out in the Explanatory Notes accompanying this Notice of Meeting and in accordance with the Rules of the Omnibus Plan (as amended from time-to-time).

R E S O L U T I O N 4

Issue of 30,010 Service Rights to the Chief Executive Officer and President, Mr. Michael Kavanagh, under the 2021 Short Term Incentive (2021 STI)

Proxy votes received Number %

For : 171,416,624 99.08

Against : 906,488 0.52

Discretion : 699,844 0.40

Abstained/Excluded : 1,406,784 -

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40Nanosonics Limited | Annual General Meeting 2021

R E S O L U T I O N 5

Resolution: That approval be given for all purposes under the Corporations Act 2001 (Cth) and the ASX Listing Rule 10.14 for the issue of 190,114 Share Appreciation Rights and 132,760 Performance Rights to Mr Michael Kavanagh under the Omnibus Plan in respect of the 2021 LTI, on the terms set out in the Explanatory Notes accompanying this Notice of Meeting and in accordance with the Rules of the Omnibus Plan (as amended from time-to-time).

Proxy votes received Number %

For : 160,928,585 93.03

Against : 11,377,958 6.58

Discretion : 681,018 0.39

Abstained/Excluded : 1,442,179 -

Issue of 190,114 Share Appreciation Rights and 132,760 Performance Rights to the Chief Executive Officer and President, Mr. Michael Kavanagh, under the 2021 Long-Term Incentive (2021 LTI)

Note: As indicated in the Notice of Meeting, the ASX 300 Industrials Index excludes companies in the energy and metal & mining industries. Nanosonics notes that the 2021 Remuneration Report includes references to the ASX300 Industrials Index incorrectly indicating that financial services are excluded from the ASX 300 Industrial Index.

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41Nanosonics Limited | Annual General Meeting 2021

Resolution: For the purposes of section 136(2) of the Corporations Act and for all other purposes, the Company’s constitution be amended by adopting in substitution for it, effective from the close of this meeting, the constitution tabled at the meeting and signed by the Chair for the purposes of identification.

Adoption of New Constitution

R E S O L U T I O N 6

Note: Since the notice of meeting was issued, the Company has clarified that it is the Company’s intention to provide shareholders with ability to attend meetings in person, potentially in conjunction with the option to attend using Virtual Meeting Technology.

Proxy votes received Number %

For : 171,020,765 98.24

Against : 161,083 0.09

Discretion : 2,896,773 1.67

Abstained/Excluded : 351,119 -

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42Nanosonics Limited | Annual General Meeting 2021

Resolution: That the proportional takeover provisions in clause 14 of the proposed new Constitution referred to in Resolution 6, take effect for a period of three years commencing on the day this special Resolution is passed.

R E S O L U T I O N 7

Proportional Takeover Provisions in Constitution

Proxy votes received Number %

For : 170,667,163 98.05

Against : 505,036 0.29

Discretion : 2,886,413 1.66

Abstained/Excluded : 371,128 -

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43Nanosonics Limited | Annual General Meeting 2021

O N L I N E A T T E N D E E S – Q U E S T I O N P R O C E S S

When the Question function is available, the Q&A icon will appear at the top of the app.

To send in a question, simply click in the ‘Ask a question’ box, type your question and the press the send arrow

Your question will be sent immediately for review

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44Nanosonics Limited | Annual General Meeting 2021

O N L I N E A T T E N D E E S – V O T I N G P R O C E S S

When the poll is open, the vote will be accessible by selecting the voting icon at the top of the screen

To vote simply select the direction in which you would like to cast your vote, the selected option will change colour.

There is no submit or send button, your selection is automatically recorded.

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45Nanosonics Limited | Annual General Meeting 2021

O N L I N E A T T E N D E E S – Q U E S T I O N P R O C E S S

When the Question function is available, the Q&A icon will appear at the top of the app.

To send in a question, simply click in the ‘Ask a question’ box, type your question and the press the send arrow

Your question will be sent immediately for review

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46Nanosonics Limited | Annual General Meeting 2021 46Nanosonics Limited | Annual General Meeting 2021

This presentation is intended to provide a general outline only and is not intended to be a definitive statement on the subject matter covered in it. The information in this presentation, whether written or verbal, has been prepared without taking into account the commercial, financial or other needs of any individual or organisation.

Certain information may relate to protected intellectual property rights owned by Nanosonics Limited (Nanosonics) and its subsidiaries (together the Group).

While due care has been taken in compiling the information based on the information available to Nanosonics at the date of this presentation material, neither Nanosonics nor its officers or advisors or any other person warrants the accuracy, reliability, completeness or timeliness of the information or guarantees the commercial or investment performance of the Group.

The information does not constitute advice of any kind and should not be relied on as such. Investors must make their own independent assessment of the Group and undertake such additional enquiries as they deem necessary or appropriate for their own investment purposes. Any and all use of the information is at your own risk.

No representation, warranty or assurance (express or implied) is given or made in relation to any forward looking statement or estimate by any person (including Nanosonics). In particular, no representation, warranty or assurance (express or implied) is given in relation to any underlying assumption or that any forward looking statement will be achieved. Actual future events may vary materially from the forward looking statements and the assumptions on which the forward looking statements are based.

Subject to any continuing obligations under applicable law or any relevant listing rules of the Australian Securities Exchange, Nanosonics disclaims any obligation or undertaking to disseminate any updates or revisions to any forward looking statements in these materials to reflect any change in expectations in relation to any forward looking statements or any change in events, conditions or circumstances on which any such statement is based. Nothing in these materials shall under any circumstances create an implication that there has been no change in the affairs of the Group since the date of these materials.

DISCLAIMER

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47Nanosonics Limited | Annual General Meeting 2021

Nanosonics Limited14 Mars Road, Lane CoveNSW 2066 Australia

T +61 2 8063 1600E [email protected]

www.nanosonics.com.au

ABN 11 095 076 896