Infection Current Awareness Update – 22/06/2020 Welcome to the weekly Infection Current Awareness Update (ICAU), produced by PHE Knowledge and Library Services. The purpose of this update is to provide you with the latest, best evidence about infection, to help you make informed decisions. Please note: PHE KLS has set up a separate COVID-19 Daily Alert of latest research. If you would like to receive this, please email libraries@phe.gov.uk. In addition to this, a page of resources about the coronavirus is available here. If you have any queries, please contact us at libraries@phe.gov.uk, and if you would like to request a literature search, please use the Knowledge and Library Services Enquiries Portal (PHE staff only). Please note that not all the articles and resources referred to in this alert are freely available. Some articles may require an Athens username and password, and for PHE and NHS staff, these can be obtained here. If you do not work for PHE or the NHS, you may want to approach your local health library service to discuss how you may have access to library services.

COVID-19 related research • COVID-19 infection - 4 Infection-related guidance • British Association for Sexual Health and HIV - 1 • British Society for Antimicrobial Chemotherapy - 1 • European Centre for Disease Prevention and Control - 2 • Infectious Diseases Society of America - 2 • Royal College of General Practitioners - 1 • Royal College of Physicians - 1 Infection-related journals • American Journal of Infection Control - 11 • American Journal of Medical Quality: Current issue - 3 • Clinical Infectious Diseases - Advance Access - 48 • Clinical Microbiology and Infection - 12 • Current Opinion in Microbiology - 1 • Current Opinion in Virology - 1 • Diagnostic Microbiology and Infectious Disease - 4 • Emerging Infectious Diseases Journal - ahead of print - 27 • European Journal of Clinical Microbiology & Infectious Diseases - 9 • Eurosurveillance latest updates - 11 • Infection - 3 • International Journal of Medical Microbiology - 1 • Infection Control & Hospital Epidemiology - FirstView Article - 17 • International Journal of Infectious Diseases - 34 • Journal of Clinical Virology - 10 • Journal of Hospital Infection - 18 • Journal of Infection - 38 • Journal of Infection Prevention - 4 • Journal of Infectious Diseases - 1 • Journal of Microbiology, Immunology and Infection - 4 • Lancet - 1 • Morbidity and Mortality Weekly Report (MMWR) - 12 • Nature Reviews Microbiology - Current Issue - 8 • New England Journal of Medicine - Current Issue - 7

• Scandinavian Journal of Infectious Diseases: Table of Contents - 13 NICE Alerts on infection related topics • NICE News - 1 NIS Affiliation • PubMed: NIS affiliation - 21

COVID-19 related research

COVID-19 infection

“Leveraging precise #geospatial information is part of the #digital revolution of health care that is required to strengthen our disease prevention systems”. Comment by David De Ridder et al. #COVID19 @Hopitaux_unige @EPFL bit.ly/2UU94db pic.twitter.com/02IbkWrUnA 18 Jun 2020

In this @CochraneUK blog for parents/carers, @siobhanmccorm, a Paediatric Specialist Registrar, looks at the latest Cochrane evidence on #MMR vaccination and at guidance on #vaccination during the current #COVID19 pandemic: buff.ly/2XSOpb2 pic.twitter.com/azn0Qg9glt 17 Jun 2020

It's World Elder Abuse Awareness Day. Violence against older people has risen sharply since the beginning of the #COVID19 pandemic & imposition of lockdown measures. @WHO & partners are providing guidance and advice for older people & care takers bit.ly/37xNYXe twitter.com/who/status/127… 15 Jun 2020

"To prevent the anticipated effects of #COVID19 on population #mentalhealth, there is an urgent need for population-scale implementation of effective public MH interventions" New Comment by @J_Campion, Afzal Javed, Norman Sartorius & @MichaelMarmot thelancet.com/journals/lanps… pic.twitter.com/8xBWREenUc 11 Jun 2020

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Infection-related guidance

British Association for Sexual Health and HIV The new guidelines for Sexual History Taking have been published. Please navigate to the Current Guidelines section. 15 Jun 2020

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British Society for Antimicrobial Chemotherapy BSAC calls for Minister to tackle superbugs and pandemics in response to inquiry on COVID-19 impact

17 Jun 2020

The post BSAC calls for Minister to tackle superbugs and pandemics in response to inquiry on COVID-19 impact appeared first on British Society for Antimicrobial Chemotherapy.

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European Centre for Disease Prevention and Control Guidance on infection prevention and control of COVID-19 in migrant and refugee reception and detention centres in the EU/EEA and the UK 15 Jun 2020

The main objective of this guidance is to provide scientific advice on public health principles and considerations for infection and prevention control of COVID-19 in migrant and refugee reception and detention centres in the European Union and European Economic Area (EU/EEA) and the United Kingdom (UK).

Rapid Risk Assessment: Coronavirus disease 2019 (COVID-19) in the EU/EEA and the UK – tenth update 11 Jun 2020

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Infectious Diseases Society of America Does blood type play a role in the severity of COVID-19 infection? New research presented in @NEJM finds that people with Type A blood may be more susceptible to severe COVID-19. bit.ly/37IvmU8 18 Jun 2020

IDSA on Twitter: "Does blood type play a role in the severity of COVID-19 infection? New research Even if your COVID-19 antibody test is positive, don't let your guard down. If a community's infection rate is low, "you’re going to have as many false positives as you have true positives,” IDSA Secretary Dr. Angela Caliendo, FIDSA of @BrownMedicine. @WSJ on.wsj.com/37uQ3mJ 15 Jun 2020

community's infection rate is low, "you’re going to have as many false positives as you have true positives,”

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Royal College of General Practitioners Royal Colleges connect with Health Minister on new blueprint for NI's health system 12 Jun 2020

Medical leaders from the Royal College of GPs, Royal College of Surgeons, Royal College of Physicians Edinburgh and Royal College of Emergency Medicine met with the Health Minister, Robin Swann to discuss his plan to rebuild Northern Ireland's health service

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Royal College of Physicians Joint statement from the Federation 18 Jun 2020

Federation is pleased to confirm that MRCP(UK) clinical and written examinations will recommence this Autumn.

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Infection-related journals

American Journal of Infection Control

The higher temperature and ultraviolet, the lower COVID-19 prevalence – Meta-regression of data from large U.S. cities 19 Jun 2020

Higher temperature and ultraviolet (UV) index in Northern Europe have been reported as the most important meteorological protective factors for the transmission of influenza virus.1 On the other hand, a recent study in China suggests that higher temperature and UV radiation may not be associated with a decrease in the epidemics of Coronavirus disease 2019 (COVID-19)

Hand Sanitizers: A Review of Ingredients, Mechanisms of Action, Modes of Delivery, and Efficacy Against Coronaviruses 18 Jun 2020

The emergence of the novel virus, SARS-CoV-2, has posed unprecedented challenges to public health around the world. Currently, strategies to deal with COVID-19 are purely supportive and preventative, aimed at reducing transmission. An effective and simple method for reducing transmission of infections in the public or healthcare settings is hand hygiene

A Review of Wipes Used to Disinfect Hard Surfaces in Healthcare Facilities 18 Jun 2020

Substantial evidence has accrued in recent years that contaminated environmental surfaces contribute to transmission of pathogens in healthcare facilities.1;2 Such surfaces can serve as sources of healthcare personnel hand contamination, which can result in transmission to susceptible patients

Antimicrobial Stewardship Intervention to Reduce Unnecessary Antibiotic Doses in Neonates 17 Jun 2020

The wording of the antibiotic duration orders for neonatal sepsis was changed as an antimicrobial stewardship initiative to reduce the administration of unnecessary antibiotic doses. The change in wording allowed the patient to stop receiving antibiotics after they received 48 hours of therapy if the health care team had not received notification of a positive culture

Catheter Securement Impact on PICC-related CLABSI: A University Hospital Perspective 17 Jun 2020

Securement solutions for intravascular catheters have provided many options in recent years. A primary focus of interest has been peripherally inserted central catheters (PICCs) and how securement attributes may be risk factors associated with central line associated blood stream infections (CLABSIs)

Molecular surveillance of methicillin-resistant Staphylococcus aureus genomes in hospital unexpectedly reveals discordance between temporal and genetic clustering 17 Jun 2020

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most important contributors to

healthcare-associated infections (HAIs), resulting in ∼20,000 deaths per year and thousands of dollars in extra costs [1-3]. Whole-genome sequencing (WGS) is increasingly being used by hospital infection control teams to elucidate infection dynamics (e.g

Issues to be considered when planning sero-epidemiological studies in regions with a low incidence of SARS-CoV-2 16 Jun 2020

The pandemic of coronavirus disease has substantially affected the healthcare systems, economy and society.1 Research on the proportions of mild or asymptomatic cases and their roles in coronavirus transmission are ongoing worldwide.2 Sero-epidemiological investigation of SARS-CoV-2 allows inferences about the extent of infection and the cumulative incidence of infection in the population

Mind the Gap: The Hospital Breakroom

16 Jun 2020

Preventing nosocomial transmission of CoVID-19 from patients to health care workers (HCW) has been a top priority for hospitals across the country. Despite rapid implementation of infection prevention practices including universal masking, early contact and droplet isolation for any patients with fever or viral symptoms, restriction of visitors, and adequate PPE supplies, we began to uncover

Meta-analysis investigating the relationship between clinical features, outcomes, and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia 12 Jun 2020

A series of pneumonia cases of unknown cause appeared in Wuhan, China in December, 2019. Scientists isolated the pathogen that caused the pneumonia, which was named 2019-nCoV, a novel type of beta-coronavirus(Zhu et al. 2020)

Epidemic characteristics of the COVID-19 outbreak in Tianjin, a well-developed city in China 12 Jun 2020

Coronavirus disease 2019 (COVID-19) is already a pandemic, and the ongoing COVID-19 outbreak has been also a big challenge for global health governance. Since the first discovery, the number of COVID-19 cases continues to rise worldwide, and almost seven million cases including 390, 000 deaths have been reported globally as of Jun 8, 2020

Rational Perspectives on Risk and Certainty for Dentistry During the COVID-19 Pandemic 11 Jun 2020

The practice of dentistry exposes dental health professionals and patients to infectious disease agents.1 The risk is considered to be higher in dental practices than in other health care settings, mainly because there is close and prolonged contact between provider and patient

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American Journal of Medical Quality: Current issue What a Difference a Disaster Makes: The Telehealth Revolution in the Age of COVID-19 Pandemic 11 Jun 2020

American Journal of Medical Quality, Ahead of Print. Despite the existence of telemedicine since the late 1950s and early 1960s, it took a pandemic to bring this technology mainstream. The critical urgency of the pandemic drove an auspicious alignment of policy, economics, and technology to facilitate the widespread implementation of telehealth

Holistic Interprofessional Program: A Collaboration Between Medical and Dental Clinics 10 Jun 2020

American Journal of Medical Quality, Ahead of Print. Why Many Quality Improvement Initiatives Die a Quick Death 10 Jun 2020

American Journal of Medical Quality, Ahead of Print. Short-term projects and improvement initiatives to parts of the organizational system are exciting in the shorter term; however, these are difficult to sustain unless these are part of an organization-wide framework to improve quality and therefore result in a change in the behavior of “the system

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Clinical Infectious Diseases - Advance Access Posterior oropharyngeal saliva for the detection of SARS-CoV-2 21 Jun 2020

AbstractBackgroundThe coronavirus disease-2019 (COVID-19) pandemic has put tremendous pressure on the healthcare system worldwide. Diagnostic testing remained one of the limiting factors for early identification and isolation of infected patients

Loss of Taste and Smell as Distinguishing Symptoms of COVID-19 21 Jun 2020

AbstractIn a household study, loss of taste and/or smell was the fourth most reported symptom (26/42; 62%) among COVID-19 case-patients and had the highest positive predictive value (83%; 95% CI: 55–95%) among household contacts. Olfactory and taste dysfunctions should be considered for COVID-19 case identification and testing prioritization.

Are separate clinical trials still required in NASH for patients with and without HIV? 20 Jun 2020

Reply to authors 20 Jun 2020

The raw Ct values from RT-PCR detection are not viral load quantitation units 20 Jun 2020

The Disproportionate Impact of COVID-19 on Racial and Ethnic Minorities in the United States 20 Jun 2020

AbstractThe COVID-19 pandemic has disproportionately affected racial and ethnic minority groups, with high rates of death in African American, Native American, and LatinX communities. While the mechanisms of these disparities are being investigated, they can be conceived as arising from biomedical factors as well as social determinants of health

Nosocomial transmission of COVID-19: a retrospective study of 66 hospital-acquired cases in a London teaching hospital 20 Jun 2020

AbstractCOVID-19 can cause deadly healthcare-associated outbreaks. In a major London teaching hospital, 66/435 (15%) of COVID-19 inpatient cases between 2 March and 12 April 2020 were definitely or probably hospital-acquired, through varied transmission routes. The case fatality was 36%. Nosocomial infection rates fell following comprehensive infection prevention and control measures.

COVID-19 and the RAAS 20 Jun 2020

Social distancing measures: evidence of interruption of seasonal influenza activity and early lessons of the SARS-CoV-2 pandemic 20 Jun 2020

Reply to Aquino-Jarquin 20 Jun 2020

To Induce IRIS or Suppress It: The spectrum of Mycobacterium genavense in the antiretroviral era 18 Jun 2020

Abstract:Mycobacterium genavense is a challenging opportunistic pathogen to diagnose and manage in HIV patients. Persistent immune suppression or protracted immune reconstitution inflammatory syndrome can lead to complicated clinical courses. We describe three cases of Mycobacterium genavense in HIV patients representing the spectrum between disease burden and strength of immune response.

A Phase 3, Randomised, Open-Label, Non-inferiority Trial Evaluating Anti-Rabies Monoclonal Antibody Cocktail (TwinrabTM) Against Human Rabies Immunoglobulin (HRIG) 17 Jun 2020

AbstractBackgroundLimited supply, cost and potential for severe adverse effects observed with the blood derived rabies immunoglobulin products has led to search for alternative therapies. This issue has been addressed by developing an antirabies monoclonal antibody cocktail

DEVELOPMENT OF AN ORDINAL SCALE TREATMENT ENDPOINT IN ADULTS HOSPITALIZED WITH INFLUENZA 17 Jun 2020

AbstractBackgroundAn obstacle in influenza therapeutics development is the lack of clinical endpoints, especially in hospitalized patients. Single time-point binary outcome measure is limited by subjects’ diverse clinical trajectories and low event rates

Implementation of a Mandatory Influenza Vaccine Program: A 10-year experience 17 Jun 2020

AbstractIntroductionInfluenza vaccination of healthcare workers (HCW) has been recommended for over 30 years. In 2009, HCWs were designated as a priority group by the Centers for Disease and Prevention (CDC). Current HCW vaccination rates are 78% across all settings, and reach approximately 92% among those employed in hospital settings

Maternal obesity and risk of early-onset neonatal bacterial sepsis: Nationwide cohort and sibling-controlled studies 17 Jun 2020

ABSTRACTBackgroundMaternal overweight and obesity are related to risks of pregnancy and delivery complications which in turn are associated with newborn infections. We examined the associations between early pregnancy body mass index (BMI, kg/m2) and risk of early-onset neonatal bacterial sepsis (EOS)

The Role of FER rs4957796 in Risk of Developing and Dying from a Bloodstream Infection: A 23-Year Follow-Up of the Population-Based HUNT Study 17 Jun 2020

ABSTRACTBackgroundBloodstream infection and sepsis are major causes of health loss worldwide, and it is important to identify subjects at risk of developing and dying from these conditions. The single nucleotide polymorphism most strongly associated with sepsis mortality is FER rs4957796. However, it is not known how this variant is associated with bloodstream infection incidence and mortality

Calcifications and the global burden of neurocysticercosis: not just rocks in your head 17 Jun 2020

Invasive Group A Streptococcal Infections among People Who Inject Drugs and People Experiencing Homelessness in the United States, 2010–2017 17 Jun 2020

ABSTRACTBackgroundReported outbreaks of invasive group A Streptococcus (iGAS) infections among people who inject drugs (PWID) and people experiencing homelessness (PEH) have increased, concurrent with rising U.S. iGAS rates. We describe epidemiology among iGAS patients with these risk factors

Xpert MTB/RIF Ultra for the Diagnosis of Tuberculous Meningitis: A Small Step Forward 16 Jun 2020

AbstractThe delayed diagnosis of tuberculous meningitis (TBM) leads to poor outcomes, yet the current diagnostic methods for identifying Mycobacterium tuberculosis in cerebrospinal fluid (CSF) are inadequate. The first comparative study of the new GeneXpert MTB/RIF Ultra (Xpert Ultra) for TBM diagnosis suggested increased sensitivity of Xpert Ultra

Performance of oropharyngeal swab testing compared to nasopharyngeal swab testing for diagnosis of COVID-19 —United States, January-February 2020 16 Jun 2020

AbstractAmong 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days since illness onset, CDC real-time RT-PCR SARS-CoV-2 assay diagnostic results were 95.2% concordant. However, NP swab Ct values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect amount of SARS-CoV-2.

Prevalence of COVID-19 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington 16 Jun 2020

ABSTRACTBackgroundHealthcare workers (HCW) serving on the front lines of the coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to SARS-CoV-2 in some settings. Healthcare-acquired infection has been reported in similar epidemics, but there are limited data on the prevalence of COVID-19 among HCWs and their associated clinical outcomes in the United States

Bacterial Pneumonia in COVID-19 critically ill patients: a case series

16 Jun 2020

Evidence in Microbiome Science: Standards for the Field (and Lab) 16 Jun 2020

Microbiomeoral microbiotaStenotrophomonasmaltophiliabacteremia16S rRNA gene Response to Dudoignon et al 16 Jun 2020

SARS-CoV-2 antibodies in adults in Madrid, Spain 16 Jun 2020

Asymptomatic and symptomatic SARS-CoV-2 infections in close contacts of COVID-19 patients: a seroepidemiological study 16 Jun 2020

Preventing COVID-19 collateral damage 16 Jun 2020

Pool size selection when testing for SARS-CoV-2 16 Jun 2020

Alterations of the oral microbiome and cumulative carbapenem exposure are associated with Stenotrophomonas maltophilia infection in patients with acute myeloid leukemia receiving chemotherapy 16 Jun 2020

AbstractBackgroundStenotrophomonas maltophilia is increasingly common in patients with acute myeloid leukemia (AML). Relatively little is known about factors that drive S. maltophilia infection. We evaluated the utility of the microbiome and cumulative antibiotic use as predictors of S. maltophilia infection in AML patients receiving remission induction chemotherapy (RIC)

Pseudomonas aeruginosa strain sharing in early infection among children with cystic fibrosis 16 Jun 2020

AbstractBackgroundWe previously identified Pseudomonas aeruginosa isolates with characteristics typical of chronic infection in some early infections in children with Cystic Fibrosis (CF), suggesting these isolates may have been acquired from other patients. Our objective was to define the extent of P

ERRATUM TO: In Vitro Activities of Ceftaroline/Avibactam, Ceftazidime/Avibactam, and Other Comparators Against Pathogens From Various Complicated Infections in China 16 Jun 2020

An error appeared in the 1 December 2018 supplement issue of the journal [Zhou M, Cheng J, Liu Y, et al. In Vitro Activities of Ceftaroline/Avibactam, Ceftazidime/Avibactam, and Other Comparators Against Pathogens From Various Complicated Infections in China. Clin Infect Dis 2018; 67(S2):S206–S216. https://doi.org/10.1093/cid/ciy659]. The second author is currently listed as Jingwei Chen

Crisis Communication and Public Perception of COVID-19 Risk in the Era of Social Media 16 Jun 2020

AbstractA number of important principles in effective risk communication established in the late 20th century can provide important scientific insight into patient response to the risks posed by COVID-19 [1-3]. Early risk communication scholars studied public perceptions of risk in response to environmental disasters, or infectious disease outbreaks

Asymptomatic SARS-CoV-2 infection and COVID-19 mortality during an outbreak investigation in a skilled nursing facility 16 Jun 2020

ABSTRACTBackgroundOutbreaks of COVID-19 have been reported in nursing homes and assisted living facilities; however, the extent of asymptomatic and pre-symptomatic SARS-CoV-2 infection in this high-risk population remains unclear

Pseudomonas aeruginosa and children with cystic fibrosis 16 Jun 2020

Corticosteroids in patients with COVID-19: what about the control group? 16 Jun 2020

The need for robust epidemiological evidence during a pandemic

16 Jun 2020

COVID-19 and Antimicrobial Resistance: Parallel and Interacting Health Emergencies 16 Jun 2020

AbstractThe COVID-19 pandemic and antimicrobial resistance are parallel and interacting health emergencies with opportunity for mutual learning. As their measures and consequences are comparable, the COVID-19 pandemic helps to illustrate the potential long-term impact of AMR, which is less acute but not less crucial

Time for Risk-Based Screening Guidelines for the Prevention of Anal Cancer? 16 Jun 2020

Risk of anal high-grade squamous intraepithelial lesions among renal transplant recipients compared with immunocompetent controls 16 Jun 2020

AbstractBackgroundRenal transplant recipients (RTRs) have increased risk of human papillomavirus (HPV)-related cancers, including anal cancer. We investigated the prevalence of anal high-grade intraepithelial lesions (HSIL) in RTRs compared with immunocompetent controls and risk factors for anal HSIL in RTRs.MethodsWe included 247 RTRs and 248 controls in this cross-sectional study

Powassan virus infection likely acquired through blood transfusion presenting as encephalitis in a kidney transplant recipient 15 Jun 2020

AbstractA kidney transplant patient without known tick exposure developed encephalitis three weeks after transplantation. During the transplant hospitalization, the patient had received a blood transfusion from an asymptomatic donor later discovered to have been infected with Powassan virus. This report describes a probable instance of transfusion-transmitted Powassan virus infection.

Tuberculosis and type 2 Diabetes Mellitus: an inflammatory danger signal in the time of COVID-19 13 Jun 2020

Impact of intermediate hyperglycaemia as well as diabetes on immune dysfunction in tuberculosis 13 Jun 2020

AbstractBackgroundPeople living with diabetes have an increased risk of developing active tuberculosis and are more likely to have poor tuberculosis-treatment outcomes, which may impact on control of tuberculosis as the prevalence of diabetes is increasing worldwide. Blood transcriptomes are altered in active tuberculosis patients relative to healthy individuals

Discriminative Ability and Reliability of Transesophageal Echocardiography in Characterizing Cases of Cardiac Device-Lead Vegetations versus Non-Infectious Echodensities 13 Jun 2020

AbstractBackgroundApproximately one third of cases of cardiovascular implantable electronic device (CIED) infection present as CIED lead infection. The precise transesophageal echocardiographic (TEE) definition and characterization of “vegetation” associated with CIED lead infection remain unclear

Reply to Nagappa and Marimuthu 12 Jun 2020

RSV---Another Serious Respiratory Infection 12 Jun 2020

Haemophilus influenzae serotype a (Hia) carriage in a small Alaska community after a cluster of invasive Hia disease, 2018 12 Jun 2020

AbstractBackgroundBetween May and July 2018, four invasive Haemophilus influenzae serotype a (iHia) infections occurred in a remote Alaska community. We performed a public health response to prevent further illness and understand Hia carriage in the community.MethodsWe collected oropharyngeal (OP) samples community-wide from untreated individuals to evaluate baseline carriage

Invasive Haemophilus influenzae type a disease: an unmet health need 12 Jun 2020

Respiratory syncytial virus associated hospitalizations among adults with chronic medical conditions 12 Jun 2020

AbstractBackgroundIn contrast with respiratory disease caused by influenza, information on the risk of respiratory syncytial virus (RSV) disease among adults with chronic medical conditions (CMCs) is limited

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Clinical Microbiology and Infection Lack of Neisseria meningitidis among pilgrims during the 2017, 2018 and 2019 Grand Magal of Touba, Senegal 21 Jun 2020

Publication date: Available online 21 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Ndiaw Goumballa, Van Thuan Hoang, Lauren Perieres, Philippe Parola, Cheikh Sokhna, Philippe Gautret

Characteristics of 1,573 healthcare workers who underwent nasopharyngeal swab for SARS-CoV-2 in Milano, Lombardy, Italy 21 Jun 2020

Publication date: Available online 20 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Andrea Lombardi, Dario Consonni, Michele Carugno, Giorgio Bozzi, Davide Mangioni, Antonio Muscatello, Valeria Castelli, Emanuele Palomba, Anna Paola Cantù, Ferruccio Ceriotti, Basilio Tiso, Angela Cecilia Pesatori, Luciano Riboldi, Alessandra Bandera, Giovanna Lunghi, Andrea Gori

High rate of pulmonary thromboembolism in patients with SARS-CoV-2 pneumonia 19 Jun 2020

Publication date: Available online 18 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Pietro Minuz, Giancarlo Mansueto, Fulvia Mazzaferri, Cristiano Fava, Andrea Dalbeni, Maria Chiara Ambrosetti, Marcella Sibani, Evelina Tacconelli

How to: interpret MICs of antifungal compounds according to the revised clinical breakpoints v. 10.0 European committee on antimicrobial susceptibility testing (EUCAST) 17 Jun 2020

Publication date: Available online 17 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Maiken Cavling Arendrup, Nathalie Friberg, Mihai Mares, Gunnar Kahlmeter, Joseph Meletiadis, Jesus Guinea, the Subcommittee on Antifungal Susceptibility Testing (AFST) of the ESCMID European Committee for Antimicrobial Susceptibility Testing (EUCAST), M.C. Arendrup, J. Meletiadis, J. Guinea, N

Efficacy and safety of weekly rifapentine and isoniazid for tuberculosis prevention in Chinese silicosis patients: a randomized controlled trial 16 Jun 2020

Publication date: Available online 15 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Qiao-ling Ruan, Xi-tian Huang, Qing-luan Yang, Xue-feng Liu, Jing Wu, Ke-chuan Pan, Yao-jie Shen, Li-min Cai, Qiao Ling, Tian Jiang, Jin-jing Hong, Xiao-dan Wang, Chun-lian Ma, Guan-qing Peng, Xiu-zhen Wang, Jin-chao Mao, Tian-zhou Wu, Miao-yao Lin, Ling-yun Shao, Wen-hong Zhang

Early outcome and safety of bedaquiline-containing regimens for treatment of MDR- and XDR-TB in China: a multicentre study 16 Jun 2020

Publication date: Available online 15 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Mengqiu Gao, Jingtao Gao, Li Xie, Guihui Wu, Wei Chen, Yu Chen, Yi Pei, Guobao Li, Yuhong Liu, Wei Shu, Lin Fan, Qianhong Wu, Juan Du, Xiaohong Chen, Peijun Tang, Yu Xiong, Mingwu Li, Qingshan Cai, Long Jin, Zaoxian Mei

Jacques F. Acar (1931 –2020) 15 Jun 2020

Publication date: Available online 11 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Emmanuelle Cambau, Laurent Gutmann, Jean-Luc Mainardi, Fred Goldstein, Annie Buu Hoi, Ekkehard Collatz, Mario Poljak, Gunnar Kahlmeter, Ian Phillips, Fernando Baquero

Disseminated Fusarium solani complex infection 15 Jun 2020

Publication date: Available online 12 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Alicia Ang, Ka Lip Chew

Dynamics and predisposition of respiratory viral co-infections in children and adults 15 Jun 2020

Publication date: Available online 12 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Yamini Mandelia, Gary W. Procop, Sandra S. Richter, Sarah Worley, Wei Liu, Frank Esper

Ibuprofen use and clinical outcomes in COVID-19 patients 15 Jun 2020

Publication date: Available online 12 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Ehud Rinott, Eran Kozer, Yonatan Shapira, Adina Bar-Haim, Ilan Youngster

Low risk for SARS-CoV2 symptomatic infection and early complications in pediatric patients during the ongoing CoVID19 epidemics in Lombardy 15 Jun 2020

Publication date: Available online 12 June 2020Source: Clinical Microbiology and InfectionAuthor(s): F. Rovida, D. Cereda, S. Novati, A. Licari, A. Triarico, G.L. Marseglia, R. Bruno, F. Baldanti, R. Bruno, M. Mondelli, E. Brunetti, A. Di Matteo, E. Seminari, L. Maiocchi, V. Zuccaro, L. Pagnucco, B. Mariani, S. Ludovisi, R. Lissandrin, A. Parisi

Antifungal therapeutic drug monitoring: focus on drugs without a clear recommendation 15 Jun 2020

Publication date: Available online 11 June 2020Source: Clinical Microbiology and InfectionAuthor(s): Alicia Gómez-López

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Current Opinion in Microbiology Microbiome-mediated regulation of anti-fungal immunity 18 Jun 2020

Publication date: December 2020Source: Current Opinion in Microbiology, Volume 58Author(s): Teresa Zelante, Claudio Costantini, Luigina Romani

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Current Opinion in Virology Reserve genetic approaches for the development of Zika vaccines and therapeutics 19 Jun 2020

Publication date: October 2020Source: Current Opinion in Virology, Volume 44Author(s): Camila R Fontes-Garfias, Coleman K Baker, Pei-Yong Shi

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Diagnostic Microbiology and Infectious Disease Diagnostic accuracy of five different Brands of Dengue Virus non-Structural Protein 1 (NS1) antigen rapid diagnostic tests (RDT) in Indonesia 21 Jun 2020

Publication date: Available online 20 June 2020Source: Diagnostic Microbiology and Infectious DiseaseAuthor(s): Marsha S. Santoso, Benediktus Yohan, Dionisius Denis, Rahma F. Hayati, Sotianingsih Haryanto, Leily Trianty, Rintis Noviyanti, Martin L. Hibberd, R. Tedjo Sasmono

In-vitro activity of Plazomicin compared to other clinically relevant aminoglycosides in Carbapenem-resistant Enterobacteriaceae

21 Jun 2020

Publication date: Available online 20 June 2020Source: Diagnostic Microbiology and Infectious DiseaseAuthor(s): Justin A. Clark, Brandon Kulengowski, David S. Burgess

Difficult-to-treat pathogens significantly reduce infection resolution in periprosthetic joint infections 21 Jun 2020

Publication date: Available online 20 June 2020Source: Diagnostic Microbiology and Infectious DiseaseAuthor(s): Matthias D. Wimmer, Gunnar T.R. Hischebeth, Thomas M. Randau, Martin Gathen, Frank Schildberg, Frank Fröschen, Hendrik Kohlhof, Sascha Gravius

COVID-19 – Six million cases worldwide and an overview of the diagnosis in Brazil: A tragedy to be announced 16 Jun 2020

Publication date: Available online 15 June 2020Source: Diagnostic Microbiology and Infectious DiseaseAuthor(s): Fernando Augusto Lima Marson

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Emerging Infectious Diseases Journal - ahead of print Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 19 Jun 2020

A. Banerjee et al. Mycobacterium bovis Pulmonary Tuberculosis after Ritual Sheep Sacrifice in Tunisia 18 Jun 2020

J. Saad et al. Rickettsioses as Major Etiologies of Unrecognized Acute Febrile Illness, Sabah, East Malaysia 18 Jun 2020

M. J. Grigg et al. Meningococcal W135 Disease Vaccination Intent, the Netherlands, 2018–2019 18 Jun 2020

L. Marion de Vries et al. Macrolide-Resistant Mycoplasma pneumoniae Infections in Pediatric Community-Acquired Pneumonia 18 Jun 2020

Y. Chen et al. Laboratory-Acquired Dengue Virus Infection, United States, 2018 18 Jun 2020

T. M. Sharp et al. Human Adenovirus Type 55 Distribution, Regional Persistence, and Genetic Variability 18 Jun 2020

J. Hang et al. Urogenital Schistosomiasis in Fisherman, Nepal, 2019 18 Jun 2020

R. Sah et al. Human Case of Severe Fever with Thrombocytopenia Syndrome Virus Infection, Taiwan, 2019 18 Jun 2020

S. Peng et al. Risk for Coccidioidomycosis among Hispanic Farm Workers, California, USA, 2018 18 Jun 2020

S. A. McCurdy et al. Paradoxal Trends in Azole-Resistant Aspergillus fumigatus in a National Multicenter Surveillance Program, the Netherlands, 2013–2018 18 Jun 2020

P. Lestrade et al. Detection and Characterization of New Coronavirus in Bottlenose Dolphin, United States, 2019 18 Jun 2020

L. Wang et al. Sub-Saharan Africa and Eurasia Ancestry of Reassortant Highly Pathogenic Avian Influenza A(H5N8) Virus, Europe, December 2019 18 Jun 2020

E. Świętoń et al. Severe Acute Respiratory Syndrome Coronavirus 2 among Asymptomatic Workers Screened for Work Resumption, China 17 Jun 2020

X. Han et al. Atypical Manifestations of Cat-Scratch Disease, United States, 2005–2014 17 Jun 2020

C. C. Nawrocki et al. Seroepidemiologic Study Designs for Determining SARS-COV-2 Transmission and Immunity 16 Jun 2020

H. Clapham et al. Public Health Role of Academic Medical Center in Community Outbreak of Hepatitis A, San Diego County, California, USA, 2016–2018 15 Jun 2020

M. Kang et al. Zika Virus Detection with 2013 Serosurvey, Mombasa, Kenya 15 Jun 2020

E. Hunsperger et al. Carbapenem Resistance Conferred by OXA-48 in K2-ST86 Hypervirulent Klebsiella pneumoniae, France 15 Jun 2020

R. Beyrouthy et al. Approach to Cataract Surgery in an Ebola Virus Disease Survivor with Prior Ocular Viral Persistence 15 Jun 2020

J. R. Wells et al. Efficient Surveillance of Plasmodium knowlesi Genetic Subpopulations, Malaysian Borneo, 2000–2018 11 Jun 2020

P. C. Divis et al. Intricacy, Symmetry, Diversity 11 Jun 2020

B. Breedlove Association of Dengue Virus and Leptospira Co-Infections with Malaria Severity 11 Jun 2020

R. Mandage et al. Shuni Virus in Wildlife and Nonequine Domestic Animals, South Africa 11 Jun 2020

J. Steyn et al. Lesions of Mycobacterium avium spp. hominissuis Infection Resembling M. bovis Lesions in a Wild Mule Deer, Canada

11 Jun 2020

K. Frayne et al. Etymologia: Rhabdomyolysis 11 Jun 2020

R. Henry Retraction: Novel Orthobunyavirus Causing Severe Kidney Disease in Broiler Chickens, Malaysia, 2014–2017 11 Jun 2020

V. Palya et al. [back to top]

European Journal of Clinical Microbiology & Infectious Diseases Group A streptococcal bacteremias in Southwest Finland 2007–2018: epidemiology and role of infectious diseases consultation in antibiotic treatment selection 18 Jun 2020

Abstract The incidence of invasive group A streptococcal (GAS) infections has shown a fluctuating but increasing trend in Finland. The impact of infectious diseases specialist consultation (IDSC) on the antimicrobial therapy of GAS bacteremia has not been studied earlier

Classification of COVID-19 patients from chest CT images using multi-objective differential evolution–based convolutional neural networks 18 Jun 2020

Abstract Early classification of 2019 novel coronavirus disease (COVID-19) is essential for disease cure and control. Compared with reverse-transcription polymerase chain reaction (RT-PCR), chest computed tomography (CT) imaging may be a significantly more trustworthy, useful, and rapid technique to classify and evaluate COVID-19, specifically in the epidemic region

How many pneumonias exist in nature? 18 Jun 2020

Evaluation of EUCAST rapid antimicrobial susceptibility testing (RAST) for positive blood cultures in clinical practice using a total lab automation 18 Jun 2020

Abstract Our objective was to evaluate EUCAST’s ‘rapid antimicrobial susceptibility testing’ (RAST) directly from positive blood culture that delivers antimicrobial results within 6 h for Staphylococcus aureus, Enterococcus spp., Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa, using total lab automation. Zone diameters from RAST were compared with MIC results

Virulence of Helicobacter pylori outer membrane proteins: an updated review 17 Jun 2020

Abstract Helicobacter pylori (H. pylori) infection is associated with some gastric diseases, such as gastritis, peptic ulcer, and gastric cancer. CagA and VacA are known virulence factors of H. pylori, which play a vital role in severe clinical outcomes. Additionally, the expression of outer membrane proteins (OMPs) helps H

Screening and evaluation of Mycobacterium tuberculosis diagnostic antigens 16 Jun 2020

Abstract In recent years, the prevalence of tuberculosis worldwide has increased, and with it, the number of drug-resistant tuberculosis strains. This has brought new challenges towards prevention and control of the disease. Therefore, it is urgent to find reliable and rapid diagnostic methods for tuberculosis in general, and for the drug-resistant forms of the disease

Detection of anti- Pneumocystis jirovecii antibodies in human serum using a recombinant synthetic multi-epitope kexin-based antigen 16 Jun 2020

Abstract Interest in the detection of specific anti-Pneumocystis jirovecii antibodies has emerged as less-invasive alternative diagnostic approaches. Here is presented the performance of an ELISA based on a recombinant synthetic multi-epitope kexin 1 (Kex1) antigen of P. jirovecii, previously developed

Effect of angiotensin II blockers on the prognosis of COVID-19: a toxicological view 16 Jun 2020

Bacterial spectrum and antibiotic resistance of urinary tract infections in patients treated for upper urinary tract calculi: a multicenter analysis 16 Jun 2020

Abstract The purpose of this study is to collect information on the bacterial resistance to antibiotics of bacteria isolated from urine cultures of patients treated for upper urinary tract calculi. Data of patients with urinary tract infection and urolithiasis were retrospectively reviewed to collect information on age, gender, stone size, location, hydronephrosis, procedure of stone removal and

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Eurosurveillance latest updates A common source for a trichinellosis outbreak reported in France and Serbia in 2017 18 Jun 2020

Trichinellosis is a rare parasitic zoonosis in the European Union. Meat from backyard pigs was the common source for a trichinellosis outbreak caused by Trichinella spiralis, which occurred in France and Serbia in the beginning of 2017. An epidemiological study was conducted in France and Serbia to determine the extent of the outbreak, to identify its source and to implement control measures

Authors’ correction for Euro Surveill. 2020;25(23) 18 Jun 2020

Prevalence of SARS-CoV-2 specific neutralising antibodies in blood donors from the Lodi Red Zone in Lombardy, Italy, as at 06 April 2020 18 Jun 2020

We evaluated SARS-CoV-2 RNA and neutralising antibodies in blood donors (BD) residing in the Lodi Red Zone, Italy. Of 390 BDs recruited after 20 February 2020 − when the first COVID-19 case in Lombardy was identified, 91 (23%) aged 19–70 years were antibody positive. Viral RNA was detected in an additional 17 (4.3%) BDs, yielding ca 28% (108/390) with evidence of virus exposure

Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020 18 Jun 2020

Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we compare 11 different RT-PCR test systems used in seven diagnostic laboratories in Germany in March 2020

Utilising sigmoid models to predict the spread of antimicrobial resistance at the country level 11 Jun 2020

Background The spread of antimicrobial resistance (AMR) is of worldwide concern. Public health policymakers and pharmaceutical companies pursuing antibiotic development require accurate predictions about the future spread of AMR

Measuring the effectiveness of an automated text messaging active surveillance system for COVID-19 in the south of Ireland, March to April 2020 11 Jun 2020

We report the effectiveness of automated text messaging for active surveillance of asymptomatic close contacts of coronavirus disease (COVID-19) cases in the Cork/Kerry region of Ireland. In the first 7 weeks of the COVID-19 outbreak, 1,336 close contacts received 12,421 automated texts. Overall, 120 contacts (9.0%) reported symptoms which required referral for testing and 35 (2

SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020 11 Jun 2020

Respiratory disease and increased mortality occurred in minks on two farms in the Netherlands, with interstitial pneumonia and SARS-CoV-2 RNA in organ and swab samples. On both farms, at least one

worker had coronavirus disease-associated symptoms before the outbreak. Variations in mink-derived viral genomes showed between-mink transmission and no infection link between the farms

Letter to the editor: Wide indication for SARS-CoV-2-testing allowed identification of international risk areas during the early phase of the COVID-19 pandemic in Germany 11 Jun 2020

Descriptive study of COVID-19 outbreak among passengers and crew on Diamond Princess cruise ship, Yokohama Port, Japan, 20 January to 9 February 2020 11 Jun 2020

An outbreak of coronavirus disease (COVID-19) occurred on the Diamond Princess cruise ship making an international journey, which led to quarantine of the ship at Yokohama Port, Japan. A suspected COVID-19 case was defined as a passenger or crew member who developed a fever or respiratory symptoms, and a confirmed COVID-19 case had laboratory-confirmation of severe acute respiratory syndrome

Meta-analysis of diagnostic performance of serological tests for SARS-CoV-2 antibodies up to 25 April 2020 and public health implications 11 Jun 2020

We reviewed the diagnostic accuracy of SARS-CoV-2 serological tests. Random-effects models yielded a summary sensitivity of 82% for IgM, and 85% for IgG and total antibodies. For specificity, the pooled estimate were 98% for IgM and 99% for IgG and total antibodies. In populations with ≤ 5% of seroconverted individuals, unless the assays have perfect (i.e

Job vacancy at the European Centre for Disease Prevention and Control (ECDC) 11 Jun 2020

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Infection Correction to: Voriconazole-induced periostitis in stem cell transplant patient 19 Jun 2020

The original version of this article unfortunately contained a mistake Secondary tension pneumothorax in a COVID-19 pneumonia patient: a case report 18 Jun 2020

Abstract Purpose Especially in elderly and multimorbid patients, Coronavirus Disease 2019 (COVID-19) may result in severe pneumonia and secondary complications. Recent studies showed pneumothorax in rare cases, but tension pneumothorax has only been reported once

Rapid radiological improvement of COVID-19 pneumonia after treatment with tocilizumab 15 Jun 2020

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International Journal of Medical Microbiology Transcriptional regulation of virulence factors Hla and phenol-soluble modulins α by AraC-type regulator Rbf in Staphylococcus aureus 17 Jun 2020

Publication date: Available online 16 June 2020Source: International Journal of Medical MicrobiologyAuthor(s): Bo Fang, Banghui Liu, Baolin Sun

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Infection Control & Hospital Epidemiology - FirstView Article

Clostridioides difficile toxin testing and positivity in Manitoba, Canada 19 Jun 2020

Published online by Cambridge University Press: Zoonotic brucellosis from the long view: Can the past contribute to the present? 19 Jun 2020

Published online by Cambridge University Press: Detecting carbapenem-resistant Acinetobacter baumannii (CRAB) carriage: Which body site should be cultured? 19 Jun 2020

Published online by Cambridge University Press: Machine learning for the prediction of antimicrobial stewardship intervention in hospitalized patients receiving broad-spectrum agents 18 Jun 2020

Published online by Cambridge University Press: Using deep learning and Twitter data to identify outpatient antibiotic misuse 18 Jun 2020

Published online by Cambridge University Press: Antimicrobial stewardship: The influence of behavioral nudging on renal-function–based appropriateness of dosing 17 Jun 2020

Published online by Cambridge University Press: Efficacy of UV-C disinfection in hyperbaric chambers 17 Jun 2020

Published online by Cambridge University Press: Description of a pharmacist-driven safety algorithm in Staphylococcus aureus bacteremia: Compliance, interventions, and good saves 16 Jun 2020

Published online by Cambridge University Press: Oral vancomycin prophylaxis against recurrent Clostridioides difficile infection: Efficacy and side effects in two hospitals 16 Jun 2020

Published online by Cambridge University Press: Control of a hospital-wide outbreak of carbapenem-resistant Acinetobacter baumannii (CRAB) using the Israeli national carbapenem-resistant Enterobacteriaceae (CRE) guidelines as a model 16 Jun 2020

Published online by Cambridge University Press: Epidemiological and genetic characterization of Clostridium butyricum cultured from neonatal cases of necrotizing enterocolitis in China 16 Jun 2020

Published online by Cambridge University Press: Variation in antibiotic use across intensive care units (ICU): A population-based cohort study in Ontario, Canada 16 Jun 2020

Published online by Cambridge University Press: Lessons learned responding to the COVID-19 pandemic 11 Jun 2020

Published online by Cambridge University Press: A framework for nosocomial transmission of emerging coronaviruses 11 Jun 2020

Published online by Cambridge University Press: Impact of anxiety and fear for COVID-19 toward infection control practices among Thai healthcare workers

08 Jun 2020

Published online by Cambridge University Press: Comprehensive investigation of an in-hospital transmission cluster of a symptomatic SARS-CoV-2–positive physician among patients and healthcare workers in Germany 03 Jun 2020

Published online by Cambridge University Press: Contamination of filtering face piece 3 masks with SARS-COV-2 during endotracheal intubation 03 Jun 2020

Published online by Cambridge University Press: [back to top]

International Journal of Infectious Diseases Progression of Lactobacillus plantarum prosthetic valve endocarditis followed by transesophageal echocardiogram 21 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Annamaria Tavernese, Maria Stelitano, Agnese Mauceri, Rocco Mollace, Giuseppe Uccello, Francesco Romeo, Valeria Cammalleri

Atypical clinical presentation of Ebola virus disease in pregnancy: Implications for clinical and public health management 21 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Boris I. Pavlin, Andrew Hall, Jan Hajek, Muhammad Ali Raja, Vikas Sharma, Otim Patrick Ramadan, Sharmistha Mishra, Audrey Rangel, Aileen Kitching, Katrina Roper, Tim O’Dempsey, Judith Starkulla, Amy Elizabeth Parry, Rashida Kamara, Alie H. Wurie

Shorter antibiotic regimens impact the control efforts in high tuberculosis burden regions of Taiwan 21 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Yi-Jun Lin, Hsing-Chieh Lin, Ying-Fei Yang, Chi-Yun Chen, Tien-Hsuan Lu, Chung-Min Liao

Nontuberculous mycobacterial bloodstream infections after allogeneic hematopoietic stem cell transplantation 21 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Akihito Nagata, Noritaka Sekiya, Yuho Najima, Masao Horiuchi, Kazuaki Fukushima, Takashi Toya, Aiko Igarashi, Takeshi Kobayashi, Kazuhiko Kakihana, Kazuteru Ohashi, Noriko Doki

Adenovirus load correlates with respiratory disease severity among hospitalized pediatric patients 21 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Yaniv Goikhman, Yaron Drori, Nehemya Friedman, Hilda Sherbany, Nathan Keller, Ella Mendelson, Rakefet Pando, Michal Mandelboim

Molecular Detection of Occult Hepatitis B virus in plasma and urine of renal transplant patients in Khartoum state Sudan 19 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Sabah A.E. Ibrahim, Sofia B. Mohamed, Sumaya Kambal, Aya Diya-Aldeen, Sara Ahmed, Batool Faisal, Fatima Ismail, Amel Ibrahim, Amel Sabawe, Osama Mohamed

Preliminary assessment of nanopore-based metagenomic sequencing for the diagnosis of prosthetic joint infection 18 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Chao-xin Wang, Zida Huang, Wei Fang, Zijie Zhang, Xinyu Fang, Wenbo Li, Bin Yang, Luyao Chen, Xiangzhi Liang, Huan Hu, Duozhi Shi, Shela Lee, Wenming Zhang

Population-based study of Helicobacter pylori infection and antibiotic resistance in Bhutan 18 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Ratha-korn Vilaichone, Natsuda Aumpan, Thawee Ratanachu-ek, Tomohisa Uchida, Lotay Tshering, Varocha Mahachai, Yoshio Yamaoka

Combination of thrombolytic and immunosuppressive therapy for coronavirus disease 2019: A case report 18 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Panagiotis Papamichalis, Antonios Papadogoulas, Periklis Katsiafylloudis, Apostolia-Lemonia Skoura, Michail Papamichalis, Evangelia Neou, Dimitrios Papadopoulos, Spyridon Karagiannis, Tilemachos Zafeiridis, Dimitris Babalis, Apostolos Komnos

Does COVID-19 infection impact on the trend of seasonal influenza infection? 11 countries and regions, from 2014 to 2020 17 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Takahiro Itaya, Yuki Furuse, Kazuaki Jindai

Estimating the burden of arboviral diseases in Colombia between 2013 and 2016 17 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Andrés Felipe Mora-Salamanca, Alexandra Porras-Ramírez, Fernando Pío De la Hoz Restrepo

A novel risk factor for predicting anti-tuberculosis drug resistance in patients with tuberculosis complicated with type 2 diabetes mellitus 16 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Mengyuan Lyu, Dongmei Wang, Junwei Zhao, Zengwei Yang, Weelic Chong, Zhenzhen Zhao, Liang Ming, Binwu Ying

Corrigendum to ‘High proportion of coxsackievirus B3 genotype A in hand, foot and mouth disease in Zhenjiang, China, 2011–2016’ International Journal of Infectious Diseases 87 (2019) 1–7 16 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Xuemin Fu, Lingxiang Mao, Zhenzhou Wan, Rong Xu, Yingying Ma, Li Shen, Xia Jin, Chiyu Zhang

Fast SARS-CoV-2 detection by RT-qPCR in preheated nasopharyngeal swab samples 16 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Julia Alcoba-Florez, Rafaela González-Montelongo, Antonio Íñigo-Campos, Diego García-Martínez de Artola, Helena Gil-Campesino, The Microbiology Technical Support Team, Laura Ciuffreda, Agustín Valenzuela-Fernández, Carlos Flores

A case of pediatric visceral leishmaniasis-related hemophagocytic lymphohistiocytosis diagnosed by mNGS 15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Fang Guo, Lei Kang, Meixian Xu

A pitfall in the diagnosis of ileocaecal tuberculosis 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Imen Ben Ismail, Hakim Zenaidi, Saber Rebii, Ayoub Zoghlami

Lack of antiviral activity of darunavir against SARS-CoV-2

15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Sandra De Meyer, Denisa Bojkova, Jindrich Cinatl, Ellen Van Damme, Christophe Buyck, Marnix Van Loock, Brian Woodfall, Sandra Ciesek

Human coronavirus data from four clinical trials of masks and respirators 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): C. Raina MacIntyre, Abrar A. Chughtai, Holly Seale, Dominic E. Dwyer, Wang Quanyi

The prominence of asymptomatic superspreaders in transmission mean universal face masking should be part of COVID-19 de-escalation strategies 15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Chris Kenyon

Ecthyma gangrenosum: An early hint for diagnosis 15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Anastasia Saade, Adrien Mirouse, Lara Zafrani

Erratum to “The effectiveness of quarantine and isolation determine the trend of the COVID-19 epidemics in the final phase of the current outbreak in China” [Int J Infect Dis (2020) 288–293/4290] 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Prevalence of culture positive Tuberculosis and utility of a clinical diagnostic tool for the diagnosis of Tuberculosis among HIV Infected Children attending HIV/AIDS Care and Treatment in Dodoma Municipality, Central Tanzania 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Sauda A. Mutabazi, Shakilu Jumanne, Bonaventura CT Mpondo, David P. Mnzava

Incidence of and risk factors for surgical site infection after colorectal surgery: A multiple-center prospective study of 3,663 consecutive patients in China 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Tie-Ying Hou, Hui-Quan Gan, Jing-Fang Zhou, Ya-Jie Gong, Liu-Yi Li, Xin-Qiang Zhang, Yue Meng, Jie-Rong Chen, Wei-Jiang Liu, Long Ye, Xiao-Xiao Wang, Yun-Hu Zhao, Yu Zhang

Adherence to standards of care and mortality in the management of Staphylococcus aureus bacteraemia in Peru: A prospective cohort study 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Alvaro Schwalb, Rodrigo Cachay, Adriana de la Flor, Coralith García, Carlos Seas

Whole exome sequencing reveals the different responsiveness to Enterovirus 71 vaccination in Chinese children 15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Li Zhang, Chengxiao Yu, Zijun Ge, Hong Tao, Fanyue Meng, Xin Xu, Ting Tian, Ci Song, Zhibin Hu, Jingxin Li, Fengcai Zhu

Unheralded Lower limb threatening ischemia in a COVID-19 patient 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Vacirca Andrea, Faggioli Gianluca, Pini Rodolfo, Teutonico Paolo, Pilato Alessandro, Gargiulo Mauro

Health economic assessment of a rabies pre-exposure prophylaxis program compared with post-exposure prophylaxis alone in high-risk age groups in the Philippines 15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Beatriz Quiambao, Lijoy Varghese, Nadia Demarteau, Ruth Faye Sengson, Jenaline Javier, Piyali Mukherjee, Leah Cheryl Manio, Scott Preiss

A 16-year retrospective study on fungal prevalence and diversity in patients with cystic fibrosis: Candida dubliniensis was associated with a decline in lung function 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Mahasin Al Shakirchi, Lena Klingspor, Peter Bergman, Lena Hjelte, Isabelle de Monestrol

Successful recovery of severe COVID-19 with cytokine storm treating with extracorporeal blood purification 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Qiang Wang, Zhao Hu

Clinical characteristics of critically ill patients co-infected with SARS-CoV-2 and the influenza virus in Wuhan, China 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Simin Ma, Xiaoquan Lai, Zhe Chen, Shenghao Tu, Kai Qin

In vitro activity of aztreonam–avibactam against metallo-β-lactamase-producing Enterobacteriaceae—A multicenter study in China 15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Biying Zhang, Zhichen Zhu, Wei Jia, Fen Qu, Bin Huang, Bin Shan, Hua Yu, Yiwei Tang, Liang Chen, Hong Du

Continuous physiological monitoring using wearable technology to inform individual management of infectious diseases, public health and outbreak responses 15 Jun 2020

Publication date: July 2020Source: International Journal of Infectious Diseases, Volume 96Author(s): Damien K. Ming, Sorawat Sangkaew, Ho Q. Chanh, Phung T.H. Nhat, Sophie Yacoub, Pantelis Georgiou, Alison H. Holmes

Social consequences of COVID-19 in a low resource setting in Sierra Leone, West Africa 15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Danilo Buonsenso, Bianca Cinicola, Francesca Raffaelli, Pietro Sollena, Francesco Iodice

Role of empiric treatment in hospitalized patients with Xpert MTB/RIF-negative presumptive pulmonary tuberculosis: A prospective cohort study 15 Jun 2020

Publication date: August 2020Source: International Journal of Infectious Diseases, Volume 97Author(s): Wakjira Kebede, Gemeda Abebe, Esayas Kebede Gudina, Elise De Vos, Emmanuel Riviere, Annelies Van Rie

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Journal of Clinical Virology Droplet digital PCR quantification suggests that higher viral load correlates with improved survival in HPV-positive oropharyngeal tumours 21 Jun 2020

Prospective study of blood viral load of Epstein-Barr virus, herpes virus type 6 and human parvovirus B19 in Crohn’s disease: Does therapy matter? 19 Jun 2020

Comparison of commercial Realtime Reverse Transcription PCR Assays for the Detection of SARS-CoV-2 17 Jun 2020

Non-polio enterovirus infections in children with central nervous system disorders in Shanghai, 2016-2018: serotypes and clinical characteristics 17 Jun 2020

Assessing the burden of viral co-infections in acute gastroenteritis in children: an eleven-year-long investigation 16 Jun 2020

Assessment of SARS-CoV-2 serological tests for the diagnosis of COVID-19 through the evaluation of three immunoassays: two automated immunoassays (Euroimmun and Abbott) and one rapid lateral flow immunoassay (NG Biotech) 15 Jun 2020

Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation 15 Jun 2020

ENTEROVIRUS D68-ASSOCIATED RESPIRATORY INFECTION IN SOUTHERN BRAZIL, 2018 – A POPULATION-BASED LABORATORY SURVEILLANCE 15 Jun 2020

Genetic diversity and molecular epidemiology of respiratory syncytial virus circulated in Antananarivo, Madagascar, from 2011 to 2017: predominance of ON1 and BA9 genotypes 15 Jun 2020

Triple positivity for Nonstructural Antigen 1, Immunoglobulin M and Immunoglobulin G is Predictive of Severe Thrombocytopaenia related to Dengue Infection 15 Jun 2020

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Journal of Hospital Infection Super-factors associated with transmission of occupational COVID-2019 infection among healthcare staff in Wuhan , China 20 Jun 2020

Globally, there have been many cases of COVID-2019 cases among medical staff, however, the main factors associated with the infection are not well understood.

The impact of implementing respiratory point-of-care testing in a regional haemato-oncology unit 19 Jun 2020

Respiratory point-of-care tests (POCT), detecting influenza A, influenza B and respiratory syncytial virus (RSV), were implemented in response to recent RSV outbreaks at a regional haemato-oncology unit in Glasgow. We provide a descriptive study of pre- and post- POCT implementation, which suggests POCT reduce the time taken to receive results and increase diagnostic rates in outpatients

Perceptions of Patients’ and Healthcare Workers’ Experiences in Cohort Isolation Units: A Qualitative Study 17 Jun 2020

Given the scarce therapeutic options for carbapenemase-producing Enterobacterales (CPE), aggressive interventions are implemented to limit its spread among hospitalized patients. One such option is contact isolation by cohorting patients in designated units.

Corrigendum to “Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents” [J Hosp Infect 104 (2020) 246–251]

17 Jun 2020

A few details in our Review require clarification or amendment. The Influence of Hospital Antimicrobial Use on Carbapenem Non-Susceptible Enterobacterales Incidence Rates According to Their Mechanism of Resistance: A Time-Series Analysis 17 Jun 2020

Carbapenem non-susceptible Enterobacterales (CNSE) can be broadly divided into those that produce carbapenemases (carbapenemase-producing Enterobacterales [CPE]), and those that harbor other mechanisms of resistance (non-carbapenemase-producing CNSE [NCP-CNSE]).

COVID-19 infections among Healthcare Workers in an Infectious Diseases specialized setting in Naples, Southern Italy: results of a cross-sectional surveillance study 17 Jun 2020

We performed a surveillance study for COVID-19 in March-April 2020 among asymptomatic HCWs in a specialized Infectious Diseases hospital in Naples, Italy. All HCWs underwent two rounds of molecular and serology testing for SARS-CoV-2. 115 HCWs were tested: two infections were identified by PT-PCR and two HCWs were SARS-CoV-2 IgG seropositive

Rapid detection of OXA-23-like, OXA-24-like and OXA-58-like carbapenemases from Acinetobacter species by real-time PCR 14 Jun 2020

Carbapenemase producing Acinetobacter species, especially A. baumannii, are often associated with treatment failures and hospital outbreaks, consequently rapid and reliable detection of specific resistance markers is paramount. The most common carbapenemases found in A

Point prevalence of penicillin allergy in hospital inpatients 14 Jun 2020

Ten percent of the general population believe themselves allergic to beta-lactams, many erroneously. Alternative, broader spectrum antibiotics are associated with increased drug costs and colonization with resistant organisms

Mapping a nosocomial outbreak of measles, coinciding with a period of sustained transmission in South London in 2018 13 Jun 2020

A measles outbreak in London is described, involving 34 cases across two hospitals and a local community across two countries. After a single introduction to hospital, spread propagated via unvaccinated retail shop workers to healthcare staff, highlighting the importance of expanding occupational health policies to non-clinical hospital staff

Quality Improvement Tool to Rapidly Identify Risk Factors for SARS-CoV-2 Infection among Healthcare Workers 13 Jun 2020

The rapid growth of the coronavirus disease 2019 (COVID-19) pandemic, limited availability of personal protective equipment, and uncertainties regarding transmission modes of the novel severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2) have heightened concerns for safety of healthcare workers (HCWs)

Incidence and characteristics of nosocomial influenza in a country with low vaccine coverage 12 Jun 2020

Influenza vaccination coverage is low in France, in at-risk patients and in healthcare workers. Aerosol Spread with Use of High-Flow Nasal Cannula: A Computational Fluid Dynamics Analysis 12 Jun 2020

Regarding the use of high-flow nasal cannula (HFNC) in COVID-19 patients, although some researchers claim that HFNC is unlikely to contaminate the surroundings, others are strongly concerned about the risk of aerosol spread with HFNC [1], [2]. Hui et al. conducted a study with mannequins and claimed that aerosol spread does not increase if HFNC is properly fitted to the face [3]

Face Masks and Containment of Coronavirus Disease 2019 (COVID-19): Experience from South Korea

12 Jun 2020

A novel coronavirus (SARS-CoV-2) emerged in the city of Wuhan, China in December 2019 and has now spread worldwide. Since the end of February 2020, the COVID-19 spread to South Korea and there was a rapid increase in COVID-19 cases from the end of February to mid-March

Sustainability of SARS-CoV-2 in aerosols: Should we worry about airborne transmission? 12 Jun 2020

SARS-CoV-2 is predominantly transmitted by respiratory droplets and contact with contaminated surfaces but the role of aerosol is debated. The usual personal protective equipment (PPE) recommended for healthcare workers (HCWs) include gown or apron, gloves, protective goggles, head cover and face mask

Enhancing departmental preparedness for COVID-19 using rapid cycle in situ simulation 12 Jun 2020

In response to COVID-19, we developed a rapid-cycle in situ simulation (ISS) programme to facilitate identification and resolution of systems-based latent safety threats. The simulation involved a possible COVID-19 case in respiratory failure, using a manikin modified to aerosolize phosphorescent secretions. 36 individuals participated in and 20 observed five ISS sessions over six weeks

Usefulness of the epidemiological survey and RT-PCR test in pre-surgical patients for assessing the risk of Covid-19 12 Jun 2020

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents one of the greatest challenges for any well-developed health care system. To date, more than 5.4 million people are infected worldwide and more tan 340.000 deaths have been reported due to Coronavirus Disease 2019 (Covid-19) (1)

Healthcare workers’ attitudes to how hand hygiene performance is currently monitored and assessed 11 Jun 2020

Engagement of healthcare workers (HCWs) is critical to maintaining high levels of hand hygiene (HH). However, attitudes of HCWs to how compliance is monitored has been poorly described. This study explored the HCW perspective on direct observation (DO) as a gold standard for HH monitoring. It also sought their opinions on innovative technology

Selection of resistance by antimicrobial coatings in the healthcare setting 11 Jun 2020

Antimicrobial touch surfaces have been introduced in healthcare settings with the aim of supporting existing hygiene procedures, and to help combat the increasing threat of antimicrobial resistance. However, concerns have been raised over the potential selection pressure exerted by such surfaces, which might drive the evolution and spread of antimicrobial resistance

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Journal of Infection Clinical presentation of Covid-19 in health care workers from a French University Hospital 21 Jun 2020

A recent study in this journal reported the environmental contamination of severe acute respiratory syndrome 2 (SARS-CoV-2) in healthcare premises1. Indeed, the health care workers (HCW) are highly exposed to SARS-CoV-2 infection and several recommendations have been made to protect them2–4

Older age is associated with sustained detection of SARS-CoV-2 in nasopharyngeal swab samples 21 Jun 2020

In this Journal, Iwasaki and colleagues compared the quality of PCR from saliva and nasopharyngeal swabs as a diagnostic measure of SARS-CoV-2 infection1. Currently, the standard for diagnosis of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) infection is a positive result based on a polymerase chain reaction (PCR) test from nasopharyngeal swab samples

The Lung Tissue Microbiota Features of 20 Deceased Patients with COVID-19 21 Jun 2020

We read with great interest the article by Yanan Chu and colleagues, accepted for publication in the Journal of Infection.1 Secondary infection and sepsis are common complications in critically ill patients with COVID-19,2, 3 but the underlying pathogen is not clear. We investigated the microbiota characteristics of lung tissue from 20 deceased COVID-19 patients

RAPID SALIVARY TEST SUITABLE FOR A MASS SCREENING PROGRAM TO DETECT SARS-COV-2: A DIAGNOSTIC ACCURACY STUDY 21 Jun 2020

In April 2020, we published in this journal an article which highlighted the role of saliva as a reliable biological fluid to detect SARS-CoV-21.

Extraspinal Articular Tuberculosis: an 11-year Retrospective Study of Demographic Features and Clinical Outcomes in East London 21 Jun 2020

The global incidence of tuberculosis (TB) infection was estimated by the WHO to be 10 million cases in 2018, 85% of whom had pulmonary TB (pTB) infection 1. In Europe, the extra-pulmonary TB (EPTB) incidence is increasing, accounting for 22.6% of new cases reported in 2017 (ECDC 2019). Furthermore, the incidence of articular TB infections has risen in Europe3, 4

Clinical feedback from experience with COVID-19: specific considerations for ExtraCorporeal Membrane Oxygenation 21 Jun 2020

A new viral severe acute respiratory syndrome coronarovirus 2 (SARS-CoV-2), was identified in the end of 2019 in China. Since then, the disease has expanded rapidly worldwide and the World Health Organization (WHO) has characterized the disease as coronavirus disease 2019 (COVID-19) and declared it as a pandemic on March 2020

Etoposide treatment adjunctive to immunosuppressants for critically ill COVID-19 patients 21 Jun 2020

In a recent article in the Journal, Cantini and colleagues1 present favorable outcomes in a small cohort of moderate COVID-19 pneumonia patients treated with lopinavir-ritonavir in addition to baricitinib, a Janus kinase inhibitor (anti-JAK). Baricitinib is a cytokine release inhibitor and is active against SARS-CoV-2 endocytosis.

Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus 21 Jun 2020

A subgroup of COVID-19 patients develop very severe disease with requirement for ICU treatment, ventilation, and ECMO therapy. Laboratory tests indicate that the immune and clotting system show marked alterations with hyper-activation, hyper-inflammation, cytokine storm development

Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibodies in Pets in Wuhan, China 21 Jun 2020

In this Journal, Hogan et al. have reported the household pet dogs and cats play important role in colonization of methicillin-resistant Staphylococcus aureus (MRSA) (1). We would like to share our findings for infection of SARS-CoV-2 in household pet cats and dogs

Persistent positivity and fluctuations of SARS-CoV-2 RNA in clinically-recovered COVID-19 patients 20 Jun 2020

As the COVID-19 pandemic slowly recedes, the number of clinically recovered subjects increases steadily. To minimize the risk of viral transmission in the community, several countries worldwide are currently endorsing a “test-based” strategy for hospital discharge and discontinuation of home-isolation, which requires 2 negative results of RT-PCR for SARS-CoV-2 RNA on nasopharyngeal swabs

Evaluation on different non-pharmaceutical interventions during COVID-19 pandemic: an analysis of 139 countries 20 Jun 2020

Since the first case of coronavirus disease 2019 (COVID-19) was confirmed, it has been spreading rapidly in various countries of the world. Various non-pharmaceutical interventions (NPIs) were reported

with possible impact to curb both local and global control of COVID19. A recent modelling study evaluated the impact of different NPIs on incidence of COVID-19 in the UK [1]

Diagnostic accuracy of the FebriDx host response point-of-care test in patients hospitalised with suspected COVID-19 20 Jun 2020

The management of COVID-19 in secondary care is severely hampered by the long turnaround times of centralised laboratory PCR testing, which can take up to several days to generate results. In acute hospitals this leads to poor patient flow though acute areas, as suspected patients are held in assessment cohort areas until their results are available

Hepatic manifestations and complications of COVID-19: A systematic review and meta-analysis 20 Jun 2020

Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), was declared a global public health emergency on 30 January 2020. Emerging data suggests that COVID-19 has extrapulmonary manifestations and complications, subsequently leading to multiorgan failure and death

Validity of the UK Early Access to Medicines Scheme Criteria for Remdesivir use in patients with COVID-19 disease 20 Jun 2020

The UK Medicines and Healthcare Products Regulatory Agency (MHRA) released its Early Access to Medicines Scheme (EAMS) criteria for the use of Remdesivir in patients with COVID-19 on May 26th, 2020.1 The MHRA Scientific Opinion supports the use of Remdesivir in patients with severe disease

CD4+T, CD8+T counts and severe COVID-19: A meta-analysis 19 Jun 2020

We read an interesting study in your journal. A retrospective study by Liu et al was conducted to investigate the associated between lymphocyte subset counts and severe COVID-19.1 They found low counts of CD4+T and CD8+T were more common in patients with severe COVID-19. And CD4/CD8 ratio showed no significant difference between non-severe and severe COVID-19 groups

Recovery from SARS-CoV-2 infection is Associated with Serum BDNF Restoration 19 Jun 2020

Acute respiratory syndrome (ARDS) is well documented as the primary manifestation of severe infection by the coronavirus 2 (SARS-CoV-2) and is considered as the leading cause of death.1 However, emerging observations indicate severe SARS-CoV-2 infection should be regarded as a systemic disease involving multiple organs

A single dose of doxycycline after an Ixodes ricinus tick bite to prevent Lyme borreliosis: an open-label randomized controlled trial 18 Jun 2020

Lyme borreliosis is the most prevalent tick-borne disease in the northern hemisphere.1 Over the last decades, marked increases in the incidence of Lyme borreliosis have been reported in several Western European countries and the United States (US), with substantial impact on public health

Outcome of Universal screening of asymptomatic neonates for COVID-19 from asymptomatic mothers 18 Jun 2020

Pandemic SARS-CoV-2 is the third Coronavirus to cause severe respiratory illness in humans. Little is known about the effects on pregnant women and the question of whether vertical transmission can occur remains unanswered and controversial.

SARS-CoV-2 and co-infections detection in nasopharyngeal throat swabs of COVID-19 patients by metagenomics 17 Jun 2020

We read with interest a recent article in this journal regarding co-infections in people with COVID-19.1 Rapid and simultaneous detection of SARS-CoV-2, the cause of COVID-19, and co-infections is essential for clinical management of COVID-19 patients

Upper airways colonisation of Streptococcus pneumoniae in adults aged 60 years and older: a systematic review of prevalence and individual participant data meta-analysis of risk factors 17 Jun 2020

Overall prevalence of pneumococcal colonisation in older adults was higher than expected but varied by risk factors. Future studies should further explore risk factors for colonisation, to highlight targets for focussed intervention such as pneumococcal vaccination of high-risk groups.

Clinically significant portal hypertension in cirrhosis patients with COVID-19: clinical characteristics and outcomes 17 Jun 2020

A recent study by Kunutsor and Laukkanen, published in the Journal of Infection, described a possible link between high levels of liver injury markers at admission and the severity and death of Coronavirus disease 2019 (COVID-19)1. This study suggests that underlying liver disease may be a risk factor for COVID-19

High SARS-CoV-2 infection rates in respiratory staff nurses and correlation of COVID-19 symptom patterns with PCR positivity and relative viral loads 17 Jun 2020

We read with interest the study in the Journal by Chen and colleagues from Nanjing, China that demonstrated a high positivity rate (17%) in healthcare workers (HCWs),1 but did not attempt to breakdown which type of HCWs working in which specialties had the highest infection rates

Clinical Characteristics and 28-Day Mortality of Medical Patients Admitted with COVID-19 to a Central London Teaching Hospital 17 Jun 2020

We read with interest the article by Galloway et al describing a clinical risk score to identify patients with COVID-19 at high risk of critical care admission or death.1 We undertook a prospective cohort study of adult patients (≥ 18 years old) with laboratory-confirmed COVID-19 admitted to the Chelsea & Westminster Hospital during a one-month period between 7th March and 7th April 2020 to

Should qualitative RT-PCR be used to determine release from isolation of COVID-19 patients? 17 Jun 2020

COVID-19 patients can continue to shed viral RNA well beyond clinical recovery.1-4 Problematically, while qualitative RT-PCR, the most commonly used diagnostic test for COVID-19, identifies SARS-CoV-2 virus genome, it fails to distinguish between viable infectious virus and noninfectious viral particles

Letter to the EditorCARDIAC INJURY AND PROGNOSIS IN COVID-19: METHODOLOGICAL CONSIDERATIONS AND UPDATED META-ANALYSIS 17 Jun 2020

We read with interest the study by Vrsalovic et al which examined the prognostic value of high-sensitive (hs) troponin in terms of mortality in patients with COVID-19.1 In patients with COVID-19, cardiac injury is not uncommon and may be attributed to ischemic and non-ischemic causes, including myocardial infarction, coronary microvascular ischemia, cytokine storm, viral myocarditis, stress

Low Transmission Risk of 9 Asymptomatic Carriers Tested Positive for both SARS-CoV-2 Nucleic Acid and Serum IgG 17 Jun 2020

We read with interest a recent prospective contact-tracing study in this Journal by Huang L and colleagues1, who reported a rapid asymptomatic transmission of COVID-19 during the incubation period demonstrating strong infectivity in a cluster of youngsters aged 16-23 years outside Wuhan. The COVID-19 pandemic has affected millions of lives worldwide partly due to its high contagiousness

Risk of subsequent ischemic stroke in patients with nontyphoidal salmonellosis: A nationwide population-based cohort study 16 Jun 2020

Stroke remains to be the priority cause of disability in human being.1 Despite much effort devoted, the rate of cryptogenic stroke still has been quoted as high as 26–40 % of patients.2 There has been a lot of traditional stroke surveillance and treatment strategies but infection usually is underestimated for it is considered an associated factor rather than a direct cause

Four point-of-care lateral flow immunoassays for diagnosis of COVID-19 and for assessing dynamics of antibody responses to SARS-CoV-2 15 Jun 2020

Since the coronavirus disease 2019 (COVID-19) emerged at the end of 2019 in Wuhan, China, it has rapidly progressed to a pandemic status and has caused tremendous repercussions on human health and life

Decreased circulating vitamin D reflects adverse outcomes of hepatitis C virus infection: A systematic review and meta-analysis 15 Jun 2020

Hepatitis C virus (HCV) infection is a leading cause of severe liver complications including fibrosis, cirrhosis, hepatic failure, and hepatocellular carcinoma (HCC)1, which is becoming a public health problem worldwide. Currently, despite availability of effective antiviral treatment for HCV infection, an unexplained variability in HCV treatment outcomes still remains2,3

Retrospective screening for SARS-CoV-2 in Greater Glasgow and Clyde ICUs between December 2019 and February 2020 15 Jun 2020

On 31st December 2019, the World Health Organization was alerted to cases of pneumonia of an unknown aetiology in Wuhan City, China [1]. The novel virus responsible, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has subsequently caused a pandemic.

Contamination of personal protective equipment by SARS-CoV-2 during routine care of patients with mild COVID-19 12 Jun 2020

We have read the article by Ye G, et al.1 with great interest. The authors found that gloves of healthcare workers (HCWs) who care coronavirus disease 19 (COVID-19) patients were frequently contaminated (15.4%) and eye protection or face shield were less contaminated (1.7%)

The role of the environment and its pollution in the prevalence of COVID-19 12 Jun 2020

Coronaviruses are a large group of viruses that can infect animals and humans and cause severe respiratory disease. In December 2019, for the first time in Wuhan, Hubei Province, China, Coronavirus was detected in humans. As of May 12, the new coronavirus has infected more than 4,256,076 people worldwide

Math and aftermath of COVID-19 pandemic and its interrelationship from the resilience perspective 12 Jun 2020

The COVID-19 pandemic is an unprecedented disastrous event in human history, shaped to a similar extent by the infective threat and the responses applied.1 The decision making processes within such a context is embedded in weighting of the potential risks and benefits stemming from these two, sometimes indistinguishable disastrous events.1,2

Detection of SARS-CoV-2 RNA in fecal specimens of patients with confirmed COVID-19: a meta-analysis 11 Jun 2020

Study Highlights Prognostic value of Carcinoembryonic antigen on outcome in patients with Coronavirus disease 2019 11 Jun 2020

Coronavirus disease 2019(COVID-19) is an infectious disease that has spread worldwide.1 Carcinoembryonic antigen (CEA) is a known tumor marker for many common cancers2,3 and reported to be high expressed in the serum of patients with severe pneumonia.4,5 In this study, we found that CEA was highly expressed in the serum of COVID-19 patients without cancer

Elevated nucleoprotein-induced interferon-γ release in COVID-19 patients detected in a SARS-CoV-2 enzyme-linked immunosorbent spot assay 11 Jun 2020

The mechanisms underlaying the host defense against SARS-CoV-2 remain largely unknown, the relative contribution and importance of the innate, humoral and cellular immune response have to be

elucidated. In a recent article in the Journal, Demey and colleagues presented data on 4 lateral flow assays (LFIA) for the detection of antibodies to SARS-CoV-2

Imported Dengue Serotype 1 Outbreak in a Non-endemic Region, China, 2017: A Molecular and Seroepidemiological Study 11 Jun 2020

Dengue, a mosquito-borne viral infection, is endemic across much of the world, with the recent expansion of its geographical range 1. In China, the southern regions of the Yangtze River, including Guangdong, Guangxi, Hainan, Fujian, and Zhejiang Provinces and in Taiwan, have suffered from endemics of dengue for many years 2, 3

The stress-inducible molecular chaperone GRP78 as potential therapeutic target for Coronavirus infection 11 Jun 2020

The current coronavirus pandemic has become the greatest threat to global public health, thus there is an urgent need for identifying therapeutic targets. A recent report in this journal by Ibrahim and colleagues describing the potential binding interaction between SARS-CoV-2 spike protein and the host 78-kDa glucose regulated protein (GRP78) raised the possibility that GRP78 could be a

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Journal of Infection Prevention Screening the nose, throat and the naso-pharynx for methicillin-resistant Staphylococcus aureus: a pilot study 13 Jun 2020

Journal of Infection Prevention, Ahead of Print. Patients who carry nasal methicillin-resistant Staphylococcus aureus (MRSA) may also harbour MRSA in the oro-pharyngeal cavity. However, the naso-oro-pharyngeal co-carriage is infrequently assessed

Diagnosis, prevention and control of urinary tract infections: a survey of routine practices in Belgian nursing homes 12 Jun 2020

Journal of Infection Prevention, Ahead of Print. Background:Urinary tract infections (UTIs) are one of the most frequently reported infections in older adults and the most common reason for antimicrobial prescribing in nursing homes (NHs)

Comparing national point prevalence surveys of healthcare-associated infection and antimicrobial prescribing: a methodological approach to adjust for differences in case-mix 10 Jun 2020

Journal of Infection Prevention, Ahead of Print. Background:National point prevalence surveys (PPS) of healthcare-associated infection (HAI) and antimicrobial prescribing in hospitals were conducted in 2011 and 2016 in Scotland. When comparing results of PPS, it is important to adjust for any differences in patient case-mix that may confound the comparison

The average peak time and intensity of seasonal influenza may vary by age: a study of laboratory confirmed influenza 10 Jun 2020

Journal of Infection Prevention, Ahead of Print. Background:Seasonal influenza (SI) is an acute respiratory illness that exerts a severe impact on human life year-round. Yet, very few studies have been conducted to investigate its peak timing for different age groups.Objective:To evaluate the average peak calendar time and intensity for the incidence of SI for different age groups

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Journal of Infectious Diseases When, Who, and How to Sample: Designing Practical Surveillance for 7 Neglected Tropical Diseases as We Approach Elimination 11 Jun 2020

AbstractAs neglected tropical disease programs look to consolidate the successes of moving towards elimination, we need to understand the dynamics of transmission at low prevalence to inform surveillance strategies for detecting elimination and resurgence

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Journal of Microbiology, Immunology and Infection Anosmia and olfactory tract neuropathy in a case of COVID-19 21 Jun 2020

Publication date: Available online 20 June 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Chia-Wen Li, Ling-Shan Syue, Yi-Shan Tsai, Min-Chi Li, Ching-Lung Lo, Chin-Shiang Tsai, Po-Lin Chen, Wen-Chien Ko, Nan-Yao Lee

Association of vitamin D levels and risk of latent tuberculosis in the hemodialysis population 15 Jun 2020

Publication date: Available online 10 June 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Shang-Yi Lin, Yi-Wen Chiu, Hui-Ru Yang, Tun-Chieh Chen, Min-Han Hsieh, Wen-Hung Wang, Yen-Hsu Chen

The first isolation and molecular characterization of Mycoplasma capricolum subsp. capripneumoniae Pakistan strain: A causative agent of contagious caprine pleuropneumonia 15 Jun 2020

Publication date: Available online 10 June 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Faisal Ahmad, Hayatullah Khan, Farhan Anwar Khan, Bryan D. Carson, Umar Sadique, Ijaz Ahmad, Muhammad Saeed, Faiz Ur Rehman, Hanif Ur Rehman

Estimation of the secondary attack rate of COVID-19 using proportional meta-analysis of nationwide contact tracing data in Taiwan 15 Jun 2020

Publication date: Available online 11 June 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Yen-Ta Huang, Yu-Kang Tu, Pei-Chun Lai

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Lancet [Department of Error] Department of Error 13 Jun 2020

Mallucci CL, Jenkinson MD, Conroy EJ, et al. Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation. Lancet 2019; 394: 1530–39—In this Article, the proportion of patients in the antibiotic shunt group and in the silver shunt group who were assessed for adverse events was incorrectly reported

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Morbidity and Mortality Weekly Report (MMWR) Heat-Related Deaths - United States, 2004-2018 18 Jun 2020

This report describes the number and rate of heat-related deaths that occurred in the United States during 2004-2018.

Outbreak of Severe Hypoglycemia After Ingestion of a Male Enhancement Supplement - Virginia, August-November 2019 18 Jun 2020

This report documents that consumers who purchase and use over-the-counter male enhancement supplements could be at risk for life-threatening complications from undeclared prescription ingredients.

QuickStats: Reason for the Most Recent Colonoscopy, Among Adults Aged 50-75 Years Who Had a Test in the Past 10 Years - National Health Interview Survey, United States, 2018 18 Jun 2020

This report describes the percentage of U.S. adults aged 50-75 years without a personal history of colorectal cancer who had a colonoscopy in the past 10 years.

Detection of Ciprofloxacin-Resistant, β-Lactamase-Producing Neisseria meningitidis Serogroup Y Isolates - United States, 2019-2020 18 Jun 2020

This report describes a novel, antibiotic-resistant strain of Neisseria meningitidis bacteria that has been detected in the United States.

Progress Toward Rubella Elimination - Western Pacific Region, 2000-2019 18 Jun 2020

This report describes progress in rubella elimination in the Western Pacific Region. EARLY RELEASE: Characteristics Associated with Hospitalization Among Patients with COVID-19 - Metropolitan Atlanta, Georgia, March - April 2020 17 Jun 2020

This report describes data findings for hospitalized and nonhospitalized COVID-19 patients from six metropolitan Atlanta, Georgia, hospitals and associated outpatient clinics.

EARLY RELEASE: Coronavirus Disease 2019 Case Surveillance - United States, January 22-May 30, 2020 15 Jun 2020

This report describes the most common underlying health conditions among COVID-19 cases in the United States as of May 30, 2020.

EARLY RELEASE: Public Attitudes, Behaviors, and Beliefs Related to COVID-19, Stay-at-Home Orders, Nonessential Business Closures, and Public Health Guidance - United States, New York City, and Los Angeles, May 5-12, 2020 12 Jun 2020

This report describes a survey taken during May among adults in the United States that found widespread support for stay-at-home orders and nonessential business closures and a high degree of adherence to COVID-19 mitigation guidelines.

Notes from the Field: Measles Outbreak on an Army Post and a Neighboring Community - El Paso, Texas, July-September 2019 11 Jun 2020

This report describes two suspected cases of measles in early July 2019 by the El Paso Department of Public Health and Army Public Health at Fort Bliss.

QuickStats: Percentage of Families That Did Not Get Needed Medical Care Because of Cost, by Poverty Status - National Health Interview Survey, United States, 2013 and 2018 11 Jun 2020

This report describes the decreased percentage from 2013 to 2018 of all families that did not get needed medical care because of cost in the past 12 months.

Trends in Pneumoconiosis Deaths - United States, 1999-2018 11 Jun 2020

This report describes the trends in pneumoconiosis-associated deaths and the need for maintaining exposure prevention measures and continued surveillance.

Notes from the Field: High Prevalence of Fentanyl Detected by the Maryland Emergency Department Drug Surveillance System - Baltimore, Maryland, 2019 11 Jun 2020

This report describes a new University of Maryland study that found that after implementing enhanced testing methods, fentanyl topped the list of drugs detected in overdose patients at two Baltimore hospital emergency departments.

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Nature Reviews Microbiology - Current Issue Coronavirus replication factories 19 Jun 2020

Nature Reviews Microbiology, Published online: 19 June 2020; doi:10.1038/s41579-020-0406-z This study suggests that double-membrane vesicles are the primary and likely only site of coronavirus viral RNA within the replication organelle.

Two birds with one stone 18 Jun 2020

Nature Reviews Microbiology, Published online: 18 June 2020; doi:10.1038/s41579-020-0401-4 A recent study identified a compound that shows bactericidal activity against both Gram-positive and Gram-negative bacteria.

Tumour-specific microbiomes 17 Jun 2020

Nature Reviews Microbiology, Published online: 17 June 2020; doi:10.1038/s41579-020-0405-0 Researchers report the most comprehensive analysis of the tumour microbiome to date.

When two fungi become one 16 Jun 2020

Nature Reviews Microbiology, Published online: 16 June 2020; doi:10.1038/s41579-020-0404-1 This study reports the discovery of human-pathogenic filamentous Aspergillus latus allodiploid hybrids that are phenotypically distinct from the parental species.

Host serotonin signals to enteric pathogens 16 Jun 2020

Nature Reviews Microbiology, Published online: 16 June 2020; doi:10.1038/s41579-020-0403-2 A recent study finds that the neurotransmitter serotonin modulates the virulence of enterohemorrhagic Escherichia coli and Citrobacter rodentium.

Biofilm dispersion 12 Jun 2020

Nature Reviews Microbiology, Published online: 12 June 2020; doi:10.1038/s41579-020-0385-0 In this Review, Rumbaugh and Sauer discuss the environmental cues and microorganism-derived signals that lead to the biofilm dispersal response, recent findings of matrix-degrading enzymes required for cells to liberate themselves from the biofilm matrix, novel insight into the mechanisms and regulation of

Epigenetic and epitranscriptomic regulation of viral replication 12 Jun 2020

Nature Reviews Microbiology, Published online: 12 June 2020; doi:10.1038/s41579-020-0382-3 In this Review, Tsai and Cullen discuss how host epigenetic and epitranscriptomic processes regulate viral gene expression at the levels of chromatin and RNA function, respectively, and explore how viruses modify, avoid or utilize these processes in order to promote their replication or persistence.

Bat-borne virus diversity, spillover and emergence 11 Jun 2020

Nature Reviews Microbiology, Published online: 11 June 2020; doi:10.1038/s41579-020-0394-z Bats harbour a large number of different viruses, some of which have spilled over to cause human disease. In this Review, Letko, Munster and colleagues discuss the diversity of bat viruses and the factors that determine the emergence of zoonotic viruses from bats.

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New England Journal of Medicine - Current Issue Challenges of “Return to Work” in an Ongoing Pandemic 18 Jun 2020

New England Journal of Medicine, Ahead of Print. Hidden in Plain Sight — Reconsidering the Use of Race Correction in Clinical Algorithms 17 Jun 2020

New England Journal of Medicine, Ahead of Print. Genomewide Association Study of Severe Covid-19 with Respiratory Failure

17 Jun 2020

New England Journal of Medicine, Ahead of Print. Amplifying RNA Vaccine Development 17 Jun 2020

New England Journal of Medicine, Volume 382, Issue 25, Page 2469-2471, June 2020. Empirical Antituberculosis Therapy in Advanced HIV Disease — Too Much, Too Late 17 Jun 2020

New England Journal of Medicine, Volume 382, Issue 25, Page 2459-2460, June 2020. Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults 17 Jun 2020

New England Journal of Medicine, Volume 382, Issue 25, Page 2397-2410, June 2020. Natural History of Asymptomatic SARS-CoV-2 Infection 12 Jun 2020

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Scandinavian Journal of Infectious Diseases: Table of Contents Aspirin enhances the clinical efficacy of anti-tuberculosis therapy in pulmonary tuberculosis in patients with type 2 diabetes mellitus 19 Jun 2020

. Of coccus, Rocco and scores: pneumococcal disease, Rocky Graziano and pneumonia severity scoring systems 19 Jun 2020

. Non-bacteremic pneumococcal pneumonia: general characteristics and early predictive factors for poor outcome 19 Jun 2020

. Targeted and universal screen in term and preterm infants for congenital CMV infection 18 Jun 2020

. Time course of anosmia and dysgeusia in patients with mild SARS-CoV-2 infection 18 Jun 2020

Volume 52, Issue 8, August 2020, Page 600-602. Tocilizumab for COVID-19: a real ‘miracle drug’? 17 Jun 2020

. To boost or not to boost? The long-term protection of people vaccinated in infancy from the perspective of the healthcare worker 17 Jun 2020

. Mortality from liver diseases attributable to hepatitis B and C in the EU/EEA – descriptive analysis and estimation of 2015 baseline 17 Jun 2020

. Third time’s the charm: COVID-19 testing issues 17 Jun 2020

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Increased CD4/CD8 ratio as a risk factor for critical illness in coronavirus disease 2019 (COVID-19): a retrospective multicentre study 16 Jun 2020

. Laboratory abnormalities related to prolonged hospitalization in COVID-19 16 Jun 2020

. Lack of perception regarding risk of dengue and day-active mosquitoes in Finnish travellers 13 Jun 2020

. The clinical impact of implementing GenMark ePlex blood culture panels for around-the-clock blood culture identification; a prospective observational study 11 Jun 2020

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NICE Alerts on infection related topics

NICE News

NICE publishes latest COVID-19 guidance on renal transplantation 19 Jun 2020

The new recommendations aim to minimise the risk of infection for patients and living donors before, during and after transplantation. They emphasise the importance of communication between patients and their specialists to ensure they can make informed decisions and understand the implications of transplantation and donation during the COVID-19 pandemic

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NIS Affiliation

PubMed: NIS affiliation

Keep calm and carry on vaccinating: Is anti-vaccination sentiment contributing to declining vaccine coverage in England? 21 Jun 2020

Related Articles Keep calm and carry on vaccinating: Is anti-vaccination sentiment contributing to declining vaccine coverage in England? Vaccine. 2020 Jun 16;: Authors: Edelstein M, Müller M, Ladhani S, Yarwood J, Salathé M, Ramsay M Abstract BACKGROUND: In England, coverage for childhood vaccines have decreased since 2012/13 in the context of an increasingly visible anti-vaccination discourse

Immunogenicity and Efficacy of Zika Virus Envelope Domain III in DNA, Protein, and ChAdOx1 Adenoviral-Vectored Vaccines. 21 Jun 2020

Related Articles Immunogenicity and Efficacy of Zika Virus Envelope Domain III in DNA, Protein, and ChAdOx1 Adenoviral-Vectored Vaccines. Vaccines (Basel). 2020 Jun 16;8(2): Authors: López-Camacho C, De Lorenzo G, Slon-Campos JL, Dowall S, Abbink P, Larocca RA, Kim YC, Poggianella M, Graham V, Findlay-Wilson S, Rayner E, Carmichael J, Dejnirattisai W, Boyd M, Hewson R, Mongkolsapaya J, Screaton

Shiga toxin-producing Escherichia coli haemolytic uraemic syndrome (STEC-HUS): diagnosis, surveillance and public-health management in England. 21 Jun 2020

Related Articles Shiga toxin-producing Escherichia coli haemolytic uraemic syndrome (STEC-HUS): diagnosis, surveillance and public-health management in England. J Med Microbiol. 2020 Jun 18;: Authors: Jenkins C, Byrne L, Vishram B, Sawyer C, Balasegaram S, Ahyow L, Johnson S PMID: 32552986 [PubMed - as supplied by publisher]

Dynamic linkage of COVID-19 test results between Public Health England's Second Generation Surveillance System and UK Biobank. 21 Jun 2020

Related Articles Dynamic linkage of COVID-19 test results between Public Health England's Second Generation Surveillance System and UK Biobank. Microb Genom. 2020 Jun 18;: Authors: Armstrong J, Rudkin JK, Allen N, Crook DW, Wilson DJ, Wyllie DH, O'Connell AM Abstract UK Biobank (UKB) is an international health resource enabling research into the genetic and lifestyle determinants of common

Monitoring the hepatitis C epidemic in England and evaluating intervention scale-up using routinely collected data. 19 Jun 2020

Related Articles Monitoring the hepatitis C epidemic in England and evaluating intervention scale-up using routinely collected data. J Viral Hepat. 2019 05;26(5):541-551 Authors: Harris RJ, Harris HE, Mandal S, Ramsay M, Vickerman P, Hickman M, De Angelis D Abstract In England, 160 000 individuals were estimated to be chronically infected with hepatitis C virus (HCV) in 2005 and the burden of

Human Herpes-8 virus copy to cell ratio: A diagnostic tool in primary effusion lymphoma. 19 Jun 2020

Related Articles Human Herpes-8 virus copy to cell ratio: A diagnostic tool in primary effusion lymphoma. J Clin Virol. 2019 07;116:7-10 Authors: Carne S, Smit E, Price N, Paul J, Guiver M, Tedder R Abstract Primary effusion lymphoma (PEL) is a serious sequel to Human Herpes Virus 8 (HHV8) infection in the immunosuppressed host

Sensitivity, specificity, inclusivity and exclusivity of the updated Aptima Combo 2 assay, which provides detection coverage of the new diagnostic-escape Chlamydia trachomatis variants. 18 Jun 2020

Related Articles Sensitivity, specificity, inclusivity and exclusivity of the updated Aptima Combo 2 assay, which provides detection coverage of the new diagnostic-escape Chlamydia trachomatis variants. BMC Infect Dis

Outbreaks of Shiga Toxin-Producing Escherichia coli Linked to Sprouted Seeds, Salad, and Leafy Greens: A Systematic Review. 18 Jun 2020

Related Articles Outbreaks of Shiga Toxin-Producing Escherichia coli Linked to Sprouted Seeds, Salad, and Leafy Greens: A Systematic Review. J Food Prot. 2019 Nov;82(11):1950-1958 Authors: Kintz E, Byrne L, Jenkins C, McCARTHY N, Vivancos R, Hunter P Abstract Shiga toxin-producing Escherichia coli (STEC) outbreaks involving ready-to-eat salad products have been described in the scientific

N1-Benzofused Modification of Fluoroquinolones Reduces Activity Against Gram-Negative Bacteria. 18 Jun 2020

Related Articles N1-Benzofused Modification of Fluoroquinolones Reduces Activity Against Gram-Negative Bacteria. ACS Omega. 2020 Jun 02;5(21):11923-11934 Authors: Laws M, Hind C, Favaron A, Jamshidi S, Evans B, Clifford M, Sutton JM, Rahman KM Abstract The fluoroquinolone class of antibiotics has a well-established structure-activity relationship (SAR) and a long history in the clinic, but the

Comparison of statistical algorithms for daily syndromic surveillance aberration detection. 18 Jun 2020

Related Articles Comparison of statistical algorithms for daily syndromic surveillance aberration detection. Bioinformatics. 2019 09 01;35(17):3110-3118 Authors: Noufaily A, Morbey RA, Colón-González FJ, Elliot

AJ, Smith GE, Lake IR, McCarthy N Abstract MOTIVATION: Public health authorities can provide more effective and timely interventions to protect populations during health events if they

Antibiotic resistance, stewardship, and consumption. 18 Jun 2020

Related Articles Antibiotic resistance, stewardship, and consumption. Lancet Planet Health. 2019 02;3(2):e66 Authors: Pouwels KB, Chatterjee A, Cooper BS, Robotham JV PMID: 30797410 [PubMed - indexed for MEDLINE]

DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis. 17 Jun 2020

Related Articles DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis. Bioinformatics. 2019 09 15;35(18):3240-3249 Authors: Yang Y, Walker TM, Walker AS, Wilson DJ, Peto TEA, Crook DW, Shamout F, CRyPTIC Consortium, Zhu T, Clifton DA Abstract MOTIVATION: Resistance co-occurrence within first-line anti-tuberculosis (TB) drugs is a common phenomenon

Characterising the risk of Hepatitis E virus infection in haematological malignancies: a UK prospective prevalence study. 17 Jun 2020

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Cost-Effectiveness of One-Time Birth Cohort Screening for Hepatitis C as Part of the National Health Service Health Check Program in England. 17 Jun 2020

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