i

i

INDEX

S.No. CONTENT Page No.

1. COMMITTEE ii

2. Scientific Programme v

3. INTRODUCTION 1

4. PRE-CONFERENCE WORKSHOP 2

5. MAIN CONFERENCE 4

i. Inaugural Session 4

ii. Group Photo - All Participants 6

6. KEY NOTE ADDRESS 7

7. SESSION: I

Symposium I: Biological Aspects of fluorosis 8

Symposium II : Molecular aspects of fluorosis 13

8. SESSION: II

NilouferChinoy Award Session 18

Symposium III: Global Epidemiological Perspectives of fluorosis 23

Symposium IV: Associated Factors and Fluorosis 29

Symposium V: Fluorosis Mitigation 36

9. POSTER SESSION

Poster Session - I

Theme: Biological and Molecular Aspects of Fluorosis

43

Poster Session – II

Theme: Epidemiology of Fluorosis

44

Poster Session – III

Theme: Mitigation of Fluorosis

45

10. NilouferChinoy award distribution 47

11. PANEL DISCUSSION 51

012. GENERAL BODY MEETING 52

13. LIST OF DELEGATES 55

14. CONFERENCE IN PRESS 57

ii

XXXIII Conference of the International Society for Fluoride Research 9-11th November 2016

International Committee

President - Dr. SunsaneeRajchagool

Vice President - Dr. Arjun L Khandare

Treasurer - Dr. Bruce spittle

Co-Secretary - Prof. DariuszChlubek

Co-Secretary - Prof. Masashi Tsunoda

National Committee Members

Dr. A.K. Susheela

Dr. A.S. Narayana

Dr. D. Raja Reddy

Dr. Sunderrajan Krishnan

Local Organizing Committee

Chief Patron - Dr. Boora NarasaishGoud

Member of Parliament (LokSabha), BhongirTelangana State, India

Chief Advisor - Dr. SoumyaSwaminathan

Convener - Sri. T. Longvah

Organizing Secretary - Dr. Arjun L Khandare

Joint Organizing Secretary - Dr. Dinesh kumar

Scientific Secretary - Dr. Bhanuprakash Reddy

Media Secretary - Dr. P Uday Kumar

Finance Secretary - Dr. VakdeviValidandi

iii

Pre-Conference Committee

Dr. J.J. Babu, Convener

Dr. I.I.Meshram, Co-Convener

Dr. Rajanna

Dr. Yadagiri Reddy

Conference Sub-Committees

Scientific Dr. Bhanuprakash Reddy, Convener

Dr. P. Raghu, Co-Convener

Dr. R. Ananthan

Registration

Dr. K. Nirmala, Convener

Ms. B.R. Annapurna,Co-Convener

Mr. D. Seetharamaiah

S. Alekhya

Ms. SGDN Lakshmi Reddy

Mr. U.V. Ramakrishna

Poster Session

Dr. Y. Venkataramana, Convener

Mr. S.Ashok

Mr. V.Bhuvaneswaran

B. Srinivas

Accommodation & Transport

Dr. N. Harishankar, Convener

Dr. P.Devaraj, Co-Convener

Mr. R.Naveen Kumar

Mr. VirendraPanpatil

Mr. R.K.Sharma

Mr. M.Srinivas

Mr. Raji Reddy

Press & Public Relations Dr. P. Uday Kumar, Convener

Dr. M. Maheshwar, Co-Convener

Dr. G.M. SubbaRao

Mr. Anil Dube

Audio-Visual & Electrical Ms. VijayaDurga, Convener

Mr. Bhujendar

iv

Venue Arrangement Dr. S.Vasanthi, Convener

Ms. AmulyaRaoCo-Convener

Ms. P.Sailaja

Website & Documentation

Dr. M. VishnuvardhanaRao, Convener

Mr. SatishBabu, Co-Convener

Catering

Mr. K.Venkaiah, Convener

Dr. J.J. BabuCo-Convener

Mr. S.Laxman

Medical Aid

Dr. N. Arlappa, Convener

Dr. M.V. Surekha, Co-Convener

Dr. B. Santosh Kumar

Secretariat

Dr. Arjun L. Khandare, Convener

Dr. Dinesh Kumar, Co-Convener

Dr. Vakdevi

Mr. G.ShankarRao

Mr. Devendran S

Mr. D.Srinivas

Ms. Sailaja K

Maintenance & Security Mr. B. Ramulu, Convener

Mr. M. Asaithurai

G. Mohan Rao

Ch. RangaRao

Michael Fernandez

Exhibition

Mr. SreenivasaRao, Convener

Mr. K.Mangthya

Mr. K.Srinivasu

Mr. Raju

Administration

Ms. Madhulatha, Convener

Mr. Murali Krishna, Co-Convener

Ms. SudhaSrinivasan

Library

Mr. Narayana

v

Scientific Programme

33rd Conference of the International Society for Fluoride Research 9-11th November, 2016

Venue: Conference Hall, National Institute of Nutrition, Hyderabad (India)

Wednesday, 9

th November 2016

PRE - CONFERENCE WORKSHOP

Time Activities

09.00 - 10.00 Registration & Inauguration

10.00 - 13.00 Pre – Conference Workshop

Session I

10.00 - 10.55 Overview and clinical diagnosis of fluorosis Dr. Arjun L Khandare

10.55 - 11.10 Tea break

11.10 - 12.05 Medical Aspects of Fluorosis Dr. Raja Reddy

12.05 - 13.00 Reconstructive and Rehabilitative Aspects of Confirmed Cases of Fluorosis Dr. Kama Raj

13.00 - 14.00 Lunch Break

14.00 - 16.00 Session II : Standardization of fluoride analyzer and analysis of fluoride in

water and urine

Dr. VakdeviValidandi

Mr. G. Shankar Rao

Mr. D. Srinivas

16.00 - 17.30

Inauguration of the Main Conference

Lighting of the Lamp

Welcome Address

Shri. T. Longvah

Director-Incharge, NIN

Conference - Introduction

Organizing Secretary

Dr. Arjun L Khandare,

Scientist-F and HoD Food

Toxicology Division, NIN

17.30 - 18.00 Key note address : Debilitating Fluorosis: Current Status, Health

Challenges & Mitigation Measures Dr. S.L. Choubisa

Vote of Thanks Dr. Dinesh Kumar,

Scientist-F and HoDDrug

Toxicology Division, NIN

18.00 - 18.30 High Tea

18.30 - 20.00 Entertainment Programme

20.00 Dinner

Venue : Assembly Hall, National Institute of Nutrition, Hyderabad (India)

Thursday, 10th

November 2016

MAIN CONFERENCE

Symposium I : Biological Aspects of Fluorosis

Chairperson : Dr. Tsunoda, Japan

Co-Chairperson: Dr. P. MahaboobBasha, India

Rapporteur : Dr. P. Raghu, NIN

Time Oral

presen-

tation

code

Title Author Name Time Poster Session

Venue : Gopalan

Block Lawns

08.00 - 9.00 Registration

09.00- 09.15 B1 Carcinogenicty of fluoride

estimated by the prevalence of

dental fluorosis

Kenji Akiniwa,

Japan

10.00 - 12.00 Poster Session I

Molecular and

biological aspects of

fluorosis – MBP1 to

MBP14

vi

Time Oral

presen-

tation

code

Title Author Name Time Poster Session

Venue : Gopalan

Block Lawns

09.15 -09.30 B2 Genetic polymorphism of col 2 a 1

gene in a population affected by

dental fluorosis

Maya Ramesh,

India

09.45 - 10.00 B4 Sodium fluoride induced toxic

responses in drosophila

melanogaster

Sumedha Roy,

India

10.00 -10.15 B5 Neurological changes delineated

by excessive fluoride ingestion:

clinical and preclinical

investigations

SandeepTripath

i, India

10.30 – 10.45 B7 To evaluate association of fluoride

with congenital anomalies in

newborns

Ghosh A, India

11.00 – 11.15 Tea/Coffee break

Symposium II : Molecular aspects of fluorosis

Chairperson :Dr. Raja Reddy, India

Co-Chairperson :Dr. Maya Ramesh, India

Rapporteur : Mr. Rajanna, NIN

11.15 – 11.30 M1 The effects of fluoride on the gene

expressions of cytokines in the

thymocytes and splenocytes from

the high IGA mice after subacute

exposure via drinking water

M Tsunoda,

Japan

11.45 – 12.00 M3 Effect of fluoride on protein

oxidation and DNA fragmentation:

a multi-generational assessment

MahaboobBasha

P, India

12.00 - 12.15 M4 Carbonic anhydrase Upregulation

plays key role in ameliorating

fluoride induced toxicity in

experimental rats supplemented

with Tamarindusindica fruit extract

Arjun L

Khandare, India

12.15 – 12.30 M5 The effect of vitamin D supplements

on antioxidant/prooxidant status on

NaF treated renal (NRK-52E) cell

lines

Semiha DEDE,

Turkey

12.45 – 13.00 M7 Acute fluoride exposure causes

cardiac dysfunction in male rats: a

biochemical and molecular

approach

Lakshmi

KanthanPanners

elvam, India

13.00 – 13.45 Lunch break

NilouferChinoy Award Session

Chairperson : Dr. A.K. Susheela, India

Co-Chairperson : Dr. Eli Dahi, Tanzania

Rapporteur : Dr. Ananthan, NIN

13.45 – 14.00 N1 Abelmoschusmoschatus seed

extract and vitamin C protects

Fluoride induced neuro-

degeneration in brain of Rats

K. Sudhakar,

India

14.00 – 16.00 Poster Session –

IIEpidemiology and

Geology of fluorosis

(EP1 to EP27)

vii

Time Oral

presen-

tation

code

Title Author Name Time Poster Session

Venue : Gopalan Block

Lawns

14.15 – 14.30 N3 Effects of quercetin on oxidative

stress and behavioral alteration in

albino wistar rat under neurotoxic

sodium fluoride exposure

M. Nageshwar,

India

14.30 – 14.45 N4 Epidemiologic risk assessment in

some fluoride affected villages of

Chhattisgarh, India

S Gupta, India

15.00 – 15.15 N6 Study of chronic fluoride toxicity in

some villages of Chandrapur

district, Maharashtra, India

SonaliDhawas,

India

15.30 – 15.45 N8 Ossification of posterior

longitudinal ligament and fluorosis

Shivanand

Reddy, India

15.45 – 16.00 Group photo

General Body Meeting

16.00 – 18.00 Brain Storming Session : Intervention Strategies for Mitigation of Fluorosis and Policies

17.45 – 18.15 Recommendations of brain Storming Session

20.00 GALA DINNER

Friday, 11th

November 2016

Symposium III : Global Epidemiological Perspectives of fluorosis

Chairperson : Dr. SemihaDeDe, Turkey

Co-Chairperson : Dr. S. Dobaradaran, Iran

Rapporteur : Dr. Devraj, NIN

08.30 -08.45 E1 Correct diagnosis of fluorosis from

other diseases with over-lapping

manifestations: rectification of

fluorosis without drugs but through

easy topractice interventions

Nisith

KumarMondal,

India

08.45 – 09.00 E2 Fluorosis and linked diseases a

new demension

A.K. Susheela,

India

09.00 – 09.15 E3 Fluorosis regulations in the united

states

Doug Cragoe,

USA

09.15 – 09.30 E4 Experience sharing on fluorosis

mitigation in Tamil Nadu.

Chowdappa,

India

09.30 – 09.45 E5 Effect evaluation of elimination of

coal-fired type of endemic fluorosis

of guizhou

Li Dasheng,

China

09.45 – 10.00 E6 Fluoride concentration of drinking

water and prevalence of dental

fluorosis

Amir

HosseinMahvi,

Iran.

10.30 – 10.45 E9 Current status of implementation of

national programme for

prevention and control of fluorosis

(NPPCF) in India

P. Saxena,

India

10.00 –

12.00

Poster Session III –

Mitigation of Fluorosis

– MP1 to MP24

10.45 – 11.00 Tea Break

Symposium IV : Associated Factors and Fluorosis

Chairperson : Dr. S.L. Chobisa, India

Co-Chairperson : Dr. Amir HosseinMahvi, Iran

Rapporteur : Dr. Jeya Kumar, NIN

viii

Time Oral

presen-

tation

code

Title Author Name

11.00 – 11.15 AF1 Climatologically control over dispersal of fluoride in

groundwater in consolidated aquifers – a study in attappady

tribal area, palghat district, Kerala, India

A. Gayen, India

11.15 – 11.30 AF2 Occurrence of high fluoride & its hydrochemical characteristics

in groundwaters in southern peri-urban part of Hyderabad city,

Telangana state

PandithMadhnure, India

11.30 – 11.45 AF3 Groundwater quality is on the brim with reference to fluoride in

rural areas of Anantapur District, Andhra Pradesh, South India

P.D.Sreedevi, India

12.00 – 12.15 AF5 Fluoride induced cytoskeletal protein changes in rat

gastrocnemius muscle- protective role of protocatechuic acid

methyl ester

Kanagaraj Vishnu Vignesh,

India

12.15 – 12.30 AF6 Integrated institutional response to tackle fluorosis:

experiences from Nalgonda, Balasore and Nagaon in India

SrinivasChekuri, India

12.30-12.45 AF7 Evaluation of fluoride enrichment processes in groundwater of

chimakurthy granitic pluton complex in PrakasamDistrcit, India

A.G.S. Reddy, India

12.45- 01.00 AF8 Integrated development program in MadhavaYadavalli, A

fluoride affected village

A.S. Narayana, India

12.30 - 13.00 General Body Meeting

13.00 - 13.45 Lunch Break

Symposium V : Fluorosis Mitigation

Chairperson : Dr. PradeepSaxena, India

Co-Chairperson : Dr. A.S. Narayana, India, India

Rapporteur : Dr. VakdeviValidandi, NIN

13.45 - 14.00 FM1 Combining water and nutrition to help recover young fluorosis

patients

Sunderrajan Krishnan, India

14.00 - 14.15 FM2 Role of tamarind seed coat in fluorosis mitigation PerumalEkambaram, India

14.15 - 14.30 FM3 Amelioration of sodium fluoride toxicity through tamarind seed

powder (tsp) on antioxidant enzymes of ovary in albino rats

VarshaDhurvey, India

14.45 - 15.00 FM5 Teaching fluorosis to undergraduates, interns and residents:

lacuna in the present medical and dental education: The way

forward

JitendraIngole, India

15.30 - 15.45 FM8 A comparative study of environmental friendly biosorbents for

removal of fluoride from aqueous solutions

S Dobaradaran, Iran

15.45 - 16.00 FM9 Africa‟s U-Turn in defluoridation Policy: From Nalgonda to

bone char

Eli Dahi, Tanzania

16.00 - 16.15 FM10 Effect of oral care products with varying fluoride concentrations

on surface micro-hardness of fluorosed enamel compared with

non fluoridated controls - an in-vitro study

R Shanbhog, India

16.45 -17.15 Certificate Distribution

17.15-17.20 Vote of Thanks &Closing Ceremony Dr. Arjun L Khandare

Organizing Secreatry

1

INTRODUCTION

Fluorosis is endemic over 25 countries across the globe and millions of

people are affected by consumption of fluoride rich ground water due to lack of

alternate economically viable solutions. In India, 21 states and union territories and

about 62 million people including 6 million children suffer from fluorosis due to

excess consumption of fluoride through drinking water. More than 90% of rural

drinking water supply programmes are based on ground water that is being over

exploited for agriculture, causing an influx of high fluoride water from the earth crust.

The spectrum of health hazards of Fluorosis range from milder form of dental

mottling to a severe form of skeletal Fluorosis that leads to paralysis of lower limbs.

Endemic fluorosis in rural India occurs because of prolonged ingestion of water with

excess fluoride resulting in significant skeletal morbidity. The skeletal morbidity is

further accentuated in children owing to rapid bone growth. Apart from the level of

fluoride in drinking water, duration of exposure, socio-economic status of the

community, age, and intake of certain food items such as tea, jowar, ragi, tamarind

etc. are known to modify the severity of the fluorosis. The influence of dietary factors

particularly calcium deficiency has been associated with high fluoride toxicity.

Concerns of increased industrial growth especially phosphate fertilizer producing

units, aluminum, iron smelting and glass manufacturing units which have been

shown to adversely affect the fluoride content in atmosphere and ground water.

There is no medicine available to treat the fluorosis, attempts to mitigate

fluoride problem have been largely concerned with defluoridation of drinking water.

However these measures were not fully successful owing to limited coverage of risk

areas as well as low awareness of the problem of fluoride in water and its associated

toxicity among populations residing in the endemic areas. Now a day's number of

studies is being carried out on the molecular mechanisms of fluoride induced toxicity

which is not well known to the researchers, academicians, NGOs.

In the light of fluorosis being an important public health problem there is an

urgent need to address various factors influencing the fluoride toxicity and evolve

intervention strategies that also include education and extension components.

2

The present conference theme is Debilitating Fluorosis: Current status Health

Challenges and Mitigation Measures, which will be covered having sub themes such

as epidemiology of Fluorosis, biological and molecular aspects of fluoride, Mitigation

of Fluorosis (nutrition, education and defluoridation), geology of fluoride, fluoride and

elemental interaction, analytical methods of detection of fluoride biological tissues,

plants and food. The conference will focus on about sub themes so as to the

international and national participants will be benefited to acquire the current

information/knowledge to get ultimate benefit to the people.

Pre-conference Workshop

The registration for the preconference workshop was commenced from 9.00

to 10.00 am on 9-11-2016. About 28 delegates (National and International)

participated in the pre-conference workshop. The preconference workshop was

encompassed with two sessions. In sessions I, three topics were covered. The

Overview and clinical diagnosis of fluorosis was presented by Dr. Arjun L Khandare,

Scientist `F‟ and HOD Food Toxicology Dsivision. The Medical Aspects of Fluorosis

was delivered by Dr. Raja Reddy, Neurosurgeon, Apollo Hospital.The Reconstructive

and Rehabilitative Aspects of Confirmed Cases of fluorosis was presented by Dr.

Kama Raj, Orthopaedician, Kamineni Hospital.In Session II,Standardization of

fluoride analyzer and analysis of fluoride in water and urine was demonstrated.

Dr. Arjun L Khandare presenting a lecture on the Fluorosis overview.

3

Demonstration of Ion selective fluoride meter

4

Main Conference Inaugural Session:

The inaugural session of the XXXIII Conference of the International Society for

Fluoride Research was hosted by several eminent personalities

Shri. T. Longvah, Director In charge, NIN, Hyderabad

Dr. Arjun L Khandare, Scientist „F‟ and Organizing Secretary, Food Toxicology

Division, NIN, Hyderabad.

Dr. Raja Reddy, Apollo Hospital, Hyderabad

Dr. S.L. Choubisa, Professor (Retd.)

Dr. VarinderGarg, Clinical Radiologist

Inaugurated the conference by lighting the lamp and the dignitaries present on the

dais also took part in the ceremony.

Shri. T. Longvah inaugurating the conference by lighting the lamp

5

The welcome address wasgiven by Director-Incharge, NIN, Shri T.Longvah and

Dr. A.L Khandare, Organizing Secretary introduced the theme of the conference to

the delegates.

Dr. Khandare addressed the invitees and said that this international conference

would serve as a platform for various researchers to come together to discuss the

current scenario on fluorosis, its toxicity and ways to mitigate the fluorosis.

Inaugural session: Dr. Arjun L Khandare addressing the participants on the

topic About the conference.

6

The release of the conference souvenir officially and distributed to all the dignitaries on

the stage.

GROUP PHOTO OF ALL PARTICIPANTS

7

Key Note Address by Dr. S.L. Choubisa

The key note address was delivered by Dr. S.L. Choubisa on the theme‟ Debilitating

fluorosis: Current status, Health Challenges and Mitigation measures. Later a lecture

was delivered by Dr. VarinderGarg MD Radiologist about the clinical and radiological

aspects of fluorosis.

The main conference was encompassed with five symposia (Symposium I: Biological

aspects of fluorosis; symposium II: Molecular aspects of fluorosis; symposium III:

Global epidemiological perspectives of fluorosis; symposium IV: Associated factors

and fluorosis; symposium V: Fluorosis mitigation) and one NilouferChinoyaward oral

session. A total of 31 oral presentations along with 5 NilouferChinoy award oral

presentations by eminent scientist and 37 poster presentations covering the topics

Biological and molecular aspects of fluorosis, epidemiology of fluorosis, mitigation of

fluorosis were presented.

8

Session: I

Symposium I: Biological Aspects of fluorosis

Dr. Kenji Akiniwa, Japan, from Japanese

Society for Fluoride Research presented

a paper on “Carcinogenicty of fluoride

estimated by the prevalence of dental

fluorosis”. He explained the

carcinogenicity of total fluoride intake from

water fluoridation and topical use is not well

documented; nevertheless dental fluorosis

caused by the use of fluoride is well known.

Observed/expected cancer prevalence

rates caused by the total daily fluoride

intake were estimated with multiplying the

cancer prevalence rate by water fluoridation

and the increased number of dental

fluorosis.

9

FLUOROSIS AND COL 2 A1 GENE

p value highly significant 0.014confidence level being a difference is (1-0.01) = 99%

confidenceFluorosis( Dean’s Index)

Chi

squarep

PCR amplicon

SizeZero 0.5 to 1

More than

1

( 2 & 3)

Total 28 29 7

Less than 700bp 1 4 0

12.49 0.014*

Equal to or

More than 700bp 9 6 6

Both

( Heterogenous) 18 19 1

Dr. Maya Ramesh

Dr. Maya Ramesh, India Associate

Professor, VMSDC, Salem presented a

paper on the "GENETIC POLYMORPHISM

OF COL 2 A 1 GENE IN A POPULATION

AFFECTED BY DENTAL FLUOROSIS”.

She explained that the collagen contains

specific amino acids and is the principal

constituent of teeth. The knowledge of

collagen gene in dental fluorosis is very less

and there were no studies on collagen

gene (COL 2 A1 gene) polymorphism in

dental fluorosis in humans. Gene mapping

was done to identify genetic polymorphism

in collagen gene. The population of the

Salem and world at large will be benefitted

by this project. If genetic polymorphism of

gene is identified, methods for gene therapy

can be identified to prevent this for the

future generations.

10

Dr. Sumedha Roy Dr. Sumedha Roy, India, Toxicology

Research Unit presented a paper on the

“SODIUM FLUORIDE INDUCED TOXIC

RESPONSES IN DROSOPHILA

MELANOGASTER”. She explained that

sodium fluoride (NaF), very commonly used

fluoride compound is composed of Na+ and

F-. Other than its use in water fluoridation,

NaF happens to be a major constituent of

several dental products like toothpastes,

mouth rinses etc. The present study

explored the toxic impact of chronic

exposure to sub-lethal concentrations of

NaF in a non-target organism, Drosophila

melanogaster.

11

Dr. SandeepTripathi Dr. SandeepTripathi, India Head (R&D)

Nationbal Referral Centre for Fluoride

Poisoning in India presented a paper on

the“NEUROLOGICAL CHANGES

DELINEATED BY EXCESSIVE FLUORIDE

INGESTION: CLINICAL AND

PRECLINICAL INVESTIGATIONS”. He

explained that the animal study revealed

that increased oxidative burden in terms of

increased lipid peroxidation and reduced

antioxidant status in fluoride treated rats.

Increased necrosis and lactate

dehydrogenase were apparent. On the

basis of results it may be concluded that

different biochemical parameters provides a

reliable indicator for monitoring the health

status of the high endemic area of fluoride

those are at risk of fluorosis. The oxidative

stress mechanism has been suggested.

12

Dr. A. Ghosh

Dr. A. Ghosh, India Department of

Biochemistry and Obstetrics and

GynaecologyPt. B. D. Sharma PGIMS,

Rohtak, Haryana presented a paper on“TO

EVALUATE ASSOCIATION OF

FLUORIDE WITH CONGENITAL

ANOMALIES IN NEWBORNS”. He

explained that the babies with congenital

defects namely anencephaly, omphalocele

and CTEV had significantly higher fluoride

levels as compared to other congenital

anomalies.However, levels in other cases

were also higher as compared to healthy

controls.

13

Symposium II : Molecular aspects of fluorosis Dr. MasashiTsunoda, Japan

Dr. MasashiTsunoda, Department of

Hygiene, KitasatoUniversity School of

Medicine, Sagamihara, Japanpresented a

paper on“THE EFFECTS OF FLUORIDE

ON THE GENE EXPRESSIONS OF

CYTOKINES IN THE THYMOCYTES AND

SPLENOCYTES FROM THE HIGHIGA

MICE AFTER SUBACUTE EXPOSURE

VIA DRINKING WATER”. He explained

that the F at 150 ppm in the drinking water

may induce inflammatory reactions in

splenic macrophages and result in the

deterioration of IgA nephritis.

14

Dr. P. MahaboobBasha, India

Dr.P. MahaboobBasha, Department of

Zoology Bangalore University,

BangaloreIndia presented a paper on

the“EFFECT OF FLUORIDE ON PROTEIN

OXIDATION AND DNA

FRAGMENTATION: A MULTI

GENERATIONALASSESSMENT”. His

findings are consistent with the hypothesis

that the multi-generational exposure to

fluoride during pregnancy is in part due to

epigenetic alterations. It can be concluded

from findings that the presence of

generational or cumulative effects of

fluoride on the progression of neuronal

impairments in the offsprings of subsequent

generations when fluoride is ingested

continuously through multiple generations.

RESULTS

FLUORIDE RETENTION AT TISSUE LEVEL

1. Considerable accumulation of fluoride was

observed in medulla oblongata,

hippocampus, cerebellum, and cerebral

cortex

2. The differential sensitivity of discrete brain

regions found in F1, F2 and F3 upon fluoride

exposure may be due to preferential fluoride

accumulation and also due to altered

biochemical and cellular processes that are

uniquely associated with or greatly enhanced

in a particular region.

15

Dr. Arjun L Khandare, India

Dr. Arjun L Khandare, Scientist-F, Food

Toxicology Division, National Institute of

Nutrition, India presented a paper on

the“CARBONIC ANHYDRASE

UPREGULATION PLAYS KEY ROLE IN

AMELIORATING FLUORIDE INDUCED

TOXICITY IN EXPERIMENTAL RATS

SUPPLEMENTED WITH TAMARINDUS

INDICA FRUIT EXTRACT”. He

documented the mechanism of action of

TFE in the amelioration of F toxicity via

carbonic anhydrase activity. This study also

identified the role of CA in reducing F

toxicity and its gene can be targeted to

upregulate its expression. Further studies

are required to elucidate the pathways

leading to the CA II upregulation on TFE

supplementation to mitigate fluorosis.

16

Dr. SemihaDede,Turkey Dr. SemihaDede, Professor, Department of

Biochemsitry, Faculty of Veterinary

Medicine,

YuzuncuYil University,Van,Turkey

presented a paper on“THE EFFECT OF

VITAMIN D SUPPLEMENTS ON

ANTIOXIDANT/PROOXIDANT STATUS

ON NAF TREATED RENAL(NRK-52E)

CELL LINES”. She observed that in the

NaFadded NRK-52E cell line, using vitamin

D have statistically important effect on TAS,

TOS and OSI index incell lysate.

• Vitamin D is well known to exert

multiple functions in bone biology,

autoimmune diseases, cell growth,

inflammation or neuromuscular and

other immune functions.

• Vitamin D, a lipid soluble molecule

usually produced after exposure to

solar ultraviolet rays.

• It is a fat-soluble vitamin present in

many foods.

• Vitamin D3 (cholecalciferol) is a

steroid hormone found in nature,

and can be acquired from various

sources, including cow milk, eggs,

fish etc.

Why vitamin D?

17

Mr. Lakshmi KanthanPannerselvam, India

Mr. Lakshmi KanthanPannerselvam, ICMR-

SRF India presented a paper on“ACUTE

FLUORIDE EXPOSURE CAUSES

CARDIAC DYSFUNCTION IN MALE

RATS: A BIOCHEMICAL A MOLECULAR

APPROACH”.He demonstrated

thatnumerous studies reveal that

hypocalcemia, hyperkalemia and cardiac

arrhythmia were involved in acute F-

induced cardiac dysfunction. Briefly,

induction of oxidative stress, apoptosis,

necrosis and altered expression of

cytoskeletal heat shock stress proteins and

AMPK signaling molecules play a crucial

role in acute F- induced cardiac dysfunction

apart from hypocalcemia and hyperkalemia.

OSI and F accumulation

7

Figure 1. F- level in serum and heart tissue of control and test animals.

Values are mean SD of six rats in each group. *p<0.05 significantly different from control. *+p<0.05, significantly

different from 45 mg F- treated rats. (One way ANOVA followed by Tukey’smultiple comparison test).

0

0.05

0.1

0.15

0.2

0.25

0.3

0.35

0.4

Control 45 mg F- 90 mg F-

OS

I

OSI

**+

*

*+

0

1

2

3

4

5

6

7

8

9

10

0

2

4

6

8

10

12

14

16

18

control 45 mg F- 90 mg F-

μg

/g

mg

/L

F- content

Serum F- Heart F-

18

Session:II NilouferChinoy Award Session

About award Mr. K. Sudhakar, India

Mr. K. Sudhakar, Research Scholar,

Neurobiology, Zoology Department,

Osmania University, India presented a

paper on

the“ABELMOSCHUSMOSCHATUS SEED

EXTRACT AND VITAMIN C PROTECTS

FLUORIDE INDUCED NEURO-

DEGENERATION IN BRAIN OF RATS”.

He demonstrated that all the experimental

results evidenced fluoride induces

neurodegeneration significantly as

compared to control group and plant &

vitamin C treated groups of rats were

observed with reduced neurodegeneration

significantly compared to fluoride treated

rats (P<0.05).

19

Mr. M. Nageshwar, India

Mr. M. Nageshwar, Research Scholar,

Neurobiology, Zoology Department,

Osmania University, India presented a

paper on“EFFECTS OF QUERCETIN ON

OXIDATIVE STRESS AND BEHAVIORAL

ALTERATION IN ALBINO WISTAR RAT

UNDER NEUROTOXIC SODIUM

FLUORIDE EXPOSURE.” He explained

that thequercetin with sodium fluoride

treatment successfully mitigated oxidative

stress in brain of rat and restored the

behavioral (maze learning) responses

compared to the rat treated with sodium

fluoride. Therefore, it can be concluded that

concomitant administration of quercetin

protects rat brain from sodium fluoride

induced oxidative stress and also

behavioral alteration in rat.

20

Ms. Shivani Gupta, India

Ms. Shivani Gupta, Research Scholar,

School of Studies in Life Sciences,

PanditRavishankarShukla University,

RaipurIndia presented a paper

on“EPIDEMIOLOGIC RISK ASSESSMENT

IN SOME FLUORIDE AFFECTED

VILLAGES OF CHHATTISGARH, INDIA.”

The results indicated that the estimated

daily intake of fluoride (CTE and RME),

HQs and HI from ingestion and the potential

risk structures is greater in the villages with

Fˉ level > 3.00 mgL-1. EDI is calculated with

different mediums of ingestion which

indicates that about 97% of the total fluoride

exposure in the study area is due to the

intake of drinking water, vegetables and soil

contributes only about 2% and 1% in it.

21

Ms. SonaliDhawas, India

Ms. SonaliDhawas, P.G.T.D. Zoology,R.t.m.

Nagpur University, NagpurIndia presented a

paper on“STUDY OF CHRONIC

FLUORIDE TOXICITY IN SOME

VILLAGES OF CHANDRAPUR DISTRICT,

MAHARASHTRA, INDIA.” Her study

revealed that 19.53% people exhibited

skeletal fluorosis. Serum samples of these

subjects showed elevated levels of fluoride

and alkaline phosphatase (ALP) and

decreased levels of calcium. Radiographic

changes suggestive of increased bone

mineral density, calcification of the

interosseous membrane, periosteal bone

formation and osteosclerosis. These

findings suggest that the excess fluoride

level in water has an impact on the human

health residing in study area.

22

23

Dr. Shivanand Reddy, India

Dr. Shivanand Reddy, Department of

Neurosurgery, Nizam‟s Institute Of Medical

Sciences India presented a paper on

the“OSSIFICATION OF POSTERIOR

LONGITUDINAL LIGAMENT AND

FLUOROSIS”.He demonstrated

thatfluorosis is associated with a higher

incidence of OPLL. Higher urinary fluoride

levels correlate with severe forms of OPLL.

24

Symposium III: Global Epidemiological Perspectives of fluorosis

Dr. Nitish Kumar Mondal, India

Dr. Nitish Kumar Mondal, Fluorosis

Foundation of India, presented a paper on the

“CORRECT DIAGNOSIS OF FLUOROSIS

FROM OTHER DISEASES WITH OVER-

LAPPING MANIFESTATIONS:

RECTIFICATION OF FLUOROSIS WITHOUT

DRUGS BUT THROUGH EASY TO

PRACTICE INTERVENTIONS”. He

demonstrated that the communication provides

an overview on Fluorosis manifestations,

diagnostic tests, results, differential diagnosis,

interventions practiced, monitored and

recovery from the disease.This report

highlights certain specific aspects of the

disease to pay attention to.

25

Dr. A. K. Susheela, India

Dr. A. K. Susheela, Executive Director

Fluorosis Research & Rural Development

Foundation, India presented a paper on

“FLUOROSIS AND LINKED DISEASES: A

NEW DEMENSION”. She demonstrated

thatthe Linked Diseases are dental

Fluorosis and extended effects in children

with thyroid hormone deficiencies, bone

deformities and Neurotoxicological effects,

renal failure leading to kidney dialysis or

kidney transplant. The new dimension

would enable the Physician to view the

disease differently. Creating awareness on

“Fluorosis Liked Diseases” is an integral

part of Fluorosis Mitigation with added

beneficial effects to those afflicted.

Mr. Doug Cragoe, USA

Mr. Doug Cragoe, USA presented a

paperon “FLUOROSIS REGULATIONS IN

THE UNITED STATES”. He explainedthat

Fluorosis prevention efforts in the United

States involve drinking water regulations

enforced by the federal Environmental

Protection Agency and state environmental

agencies, as well as printed warnings on

fluoride toothpaste to avoid ingestion.

26

Dr. Chowdappa, India

Dr. Chowdappa,STEM, Bengaluru, India

presented a paper on“EXPERIENCE

SHARING ON FLUOROSIS MITIGATION

IN TAMIL NADU”. He explained that Tamil

Nadu is having 32 districts with population

of 62.1 million. Out of 32 districts 9 districts

are endemic for fluorosis.2 districts i.e.,

Dharmapuri and Krishnagiri districts having

fluoride levels in the ground water in the

range of 1.5 mg/l to 12.4 mg/l.The

interventions strategies include Diet

Counselling and Nutritional

Supplementation,Reconstructive Surgeries

and Rehabilitative Measures, Health

Education.

27

Dr. Li Dasheng, China

Dr. Li Dasheng, Guizhou,China presented a

paper on the“EFFECT EVALUATION OF

ELIMINATION OF COAL-FIRED TYPE OF

ENDEMIC FLUOROSIS OF GUIZHOU”. He

demonstrated that theoverall prevalence of

dental fluorosis of 37 countries was 9.42%,

in which 31 counties meet the Control

Standards (dental fluorosis prevalence <

30%), 26 countries the Eliminate

Standard(dental fluorosis prevalence

<15%).It is concluded that Guizhou has

effectively controlled the endemic fluorosis,

and the elimination target has been

achieved, from which about 13 million

people benefit.

28

Dr. Amir HosseinMahvi, Iran

Dr. Amir HosseinMahvi, Department of

Environmental Health Engineering, School

of Public Health, Tehran University of

Medical Sciences; Tehran, Iran presented a

paper on the“Fluoride Concentration of

Drinking Water and Prevalence of Dental

Fluorosis”. He demonstrated that a

comprehensive study was carried out using

4 electronic databases including PubMed,

Scopus, SID and IranMedex. Inclusion

criteria were predefined and some articles

met them. Study validity was assessed with

some checklists. Surveys were conducted

to ascertain dental fluorosis prevalence

among individuals. The findings of this

study provide researches with a

comprehensive outlook on the literature of

fluoride concentration of drinking water and

prevalence of dental fluorosis.

29

Dr. PradeepSaxena, India

Dr. PradeepSaxena, Additional DDG,

Dte.General Health Services,M/o Health &

F.W., Govt of India, New DelhiIndia

presented a paper on “CURRENT STATUS

OF IMPLEMENTATION OF NATIONAL

PROGRAMME FOR PREVENTION AND

CONTROL FLUOROSIS (NPPCF) IN

INDIA.” He explained that the main

components of the programme are

surveillance of fluorosis cases in the

community; capacity building in the form of

training and manpower support;

establishment of laboratory diagnostic

facilities at the district level to test water and

urinary fluoride levels; health education;

management of fluorosis cases including

surgery and rehabilitation. Efforts are made

for close collaboration with the Ministry of

30

Drinking Water and Sanitation to provide

safe drinking water in the affected areas.

31

Symposium IV: Associated Factors and Fluorosis

Mr. Gayen, India presented a paper

on“CLIMATOLOGICAL CONTROL OVER

DISPERSAL OF FLUORIDE IN

GROUNDWATER IN CONSOLIDATED

AQUIFERS – A STUDY IN ATTAPPADY

TRIBAL AREA, PALGHAT DISTRICT,

KERALA, INDIA”. His present study on

fluoride contamination in surface water and

groundwater in and around Attappady tribal

area of Palghat district, Kerala state, India

reveals that fluoride dispersal is primarily

controlled by source rocks and their

structures. Additional controlling factors are

hydrogeomorphology, drainage network and

climatic condition prevailing in the area.

32

Dr. PandithMadhnure, India

Dr. PandithMadhnure, Central Ground

Water BoardMinistry of Water

Resources,River Development & Ganga

Rejuvenation India presented a paper

on“OCCURRENCE OF HIGH FLUORIDE &

ITS HYDROCHEMICAL

CHARACTERISTICS IN

GROUNDWATERS IN SOUTHERN PERI-

URBAN PART OF HYDERABAD CITY,

TELANGANA STATE.”He explained that

theartificial recharge structures like

percolation tanks and check dams in 177

km2 areas where thick weathered and de-

saturated zone is available, de-silting of

existing tanks under “Mission Kakatiya” (90

minor and 1 medium) and supplying of

surface water under “Mission Bhagiratha”

are recommended.

33

Dr. P.D. Sreedevi, India

Dr. P.D. Sreedevi, Central Ground Water

BoardMinistry of Water Resources,River

Development & Ganga Rejuvenation India

presented a paper on“GROUNDWATER

QUALITY IS ON THE BRIM WITH

REFERENCE TO FLUORIDE IN RURAL

AREAS OF ANANTAPUR DISTRICT,

ANDHRA PRADESH, AND SOUTH

INDIA”. She explained thatthe

concentration of F- in groundwater ranges

from 0.8 to 3.8 mg/l and 0.9 to 4.1 mg/l

mean of 2.1 and 2.3 mg/l in both the seasons. It is observed that 78% and 83% of

groundwater samples are exceeding the maximum permissible limits (1.5 mg/l) of

drinking water standards in both the seasons.F-has shown anegative correlation with

Ca2+and the positive correlation with pH, HCO3- and Na+. Enrichment of F-in the

groundwater is due to increase the dissolution/solubility of F-bearing minerals,

leading to F-leaching into groundwater it is totally geogenicactivityin the study area.

34

Mr. Kanagaraj Vishnu Vignesh

Mr. Kanagaraj Vishnu Vignesh, DST-SERB-

JRFMolecular Toxicology LabDepartment

of Biotechnology,

BharahtiarUniveristyIndia presented a

paper on“FLUORIDE INDUCED

CYTOSKELETAL PROTEIN CHANGES IN

RAT GASTROCNEMIUS MUSCLE-

PROTECTIVE ROLE OF

PROTOCATECHUIC ACID METHYL ESTER”.He demonstrated that the chronic

exposure to fluoride to soft tissue such as skeletal muscle causes deleterious effect

is a well-established fact. Cytoskeletal proteins desmin and vimentin which are

predominately found in the skeletal muscle are the major structural and functional

support during the process of contraction and relaxation. The chronic exposure of

fluoride in the gastrocnemius muscle causes changes in biochemical as well as

molecular level expression of both desmin and vimentin.

35

Mr. SrinivasChekuri, India

Mr. SrinivasChekuri, India presented a

paper on “INTEGRATED INSTITUTIONAL

RESPONSE TO TACKLE FLUOROSIS:

EXPERIENCES FROM NALGONDA,

BALASORE AND NAGAON IN INDIA”. He

demonstrated thatin 3 year experience now

of Nalgonda, few more examples have now

followed, most notably those at Balasore in

Odisha and Nagaon in Assam. All these

institutions are at an early stage and they all

show very interesting mix of government

convergence aided by a local, regional and national ecosystem of actors put together

as a network of institutions working on the fluorosis issue. The experiences coming

out from these field experiments which all are attempting an integrated response to

Fluorosis, is critical in planning further such expansion of the basic idea. The

potential of this idea seems vast and promising till now

36

Dr. A.G.S. Reddy,India

Dr. A.G.S. Reddy presented a paper on

EVALUATION OF FLUORIDE

ENRICHMENT PROCESSES IN

GROUNDWATER OF CHIMAKURTHY

GRANITIC PLUTON COMPLEX,

PRAKASAM DIST, AP, INDIA. HE

DEMONSTRATED THAT THE F-

concentration of rock-soil-groundwater does

not synchronize depicting latter enrichment

of F- into formation water. Ratios, indices

and plots indicate multiple mechanisms

were responsible in F- absorption into

groundwater. Water-rock interactions, ion

exchange followed by evapotranspiration

have facilitated the F- mineralization of

groundwater.

37

Dr. A. S. Narayana, India

Dr. A. S. Narayana, Padmasri

Awardee,India presented a paper

on“Integrated Development Program

inMadhavaYadavalli, A Fluoride affected

village”. He explained about the

household, villagers, anganwadicentre,

primary schools etc in the villages. He also

explained about the registered

symptoms,socio-economic symptoms of

fluorosis in the villages etc.

38

Symposium V: Fluorosis Mitigation

Dr. Sunderrajan Krishnan, India

Dr. Sunderrajan Krishnan, India presented a

paper on“COMBINING WATER AND

NUTRITION TO HELP RECOVER YOUNG

FLUOROSIS PATIENTS.”He explained

that the condition of juvenile skeletal

fluorosis is unique in that it is a mix of both

high Fluoride entering the body, as well as

Malnutrition. For addressing such cases,

one needs a combined approach for both

safe water and good nutrition. As a result of all these approaches, there has been a

recovery of bone deformities in 5 children and many improvements in others. The

programmes have now been scaled to 28 villages in Jhabua with similar results. This

approach shows a unique way of tackling Juvenile Skeletal Fluorosis and helping

children recover from deformity.

Nilesh of Jashoda Khumji– May-2010

Nilesh of Jashoda Khumji – Dec-2012

39

Dr. PerumalEkambaram

Dr. PerumalEkambaram, Assistant

ProfessorMolecular Toxicology Laboratory

Department of Biotechnology Bharathiar

University Coimbatore – 641 046,

Tamilnadu, India presented a paper

on“ROLE OF TAMARIND SEED COAT IN

FLUOROSIS MITIGATION”. He

demonstrated thattill date there is no

effective therapeutics available for fluorosis.

Plants and their secondary metabolites

seem to reduce fluoride toxicity. Hence, the

beneficial effects of tamarind seed coat

against fluoride toxicity were assessed in

vitro - A549 cells andin vivo - rat lungs.

Tamarind seed coat supplementation

decreased fluoride accumulation in A549

cells and in rat lung tissues.

40

Dr. VarshaDhurvey, India

Dr.VarshaDhurvey, P.G.T.D. Zoology, Rtm

Nagpur University, Nagpur (M.S.) India

presented a paper on“AMELIORATION OF

SODIUM FLUORIDE TOXICITY THROUGH

TAMARIND SEED POWDER (TSP) ON

ANTIOXIDANT ENZYMES OF OVARY IN

ALBINO RATS”. She explained thatthe

ameliorative effect of combined treatment

(NaF+TSP – tamarind seed powder)

showed restoration in ovarian antioxidant

enzymes. It concluded that combined

treatment recovered or altered potent

antioxidants reduced oxidative stress and

regained the antioxidant homeostasis of

ovary.

41

Dr. JitendraIngole, India

Dr. JitendraIngole, MD Internal Medicine,

Professor, Dept of Medicine SKN Medical

College, Pune,India presented a paper

on“TEACHING FLUOROSIS TO

UNDERGRADUATES, INTERNS AND

RESIDENTS; LACUNA IN THE PRESENT

MEDICAL AND DENTAL EDUCATION:

THE WAY FORWARD”. He explained that

the fluorosis is neglected entity in

community as well as amongst medical

fraternity. Textbooks may not offer detailed

coverage of fluorosis. The minds of medical students are not being impressed upon

with the fluorosis epidemiology, clinical effects & prevention. The very fact that there

no active treatment or any drug; discourages interest of practicing clinicians in this

area. The vicious circle needs to be broken. There is equal need of reawakening for

medical students (undergraduate & postgraduate), medical teachers, authors,

medical/dental universities for better awareness and treatment of fluorosis.

42

Dr. S. Dobaradaran, Iran

Dr. S. Dobaradaran, The Persian Gulf Marine

Biotechnology Medicine Research Center,

Bushehr University of Medical Sciences,

Bushehr,Iran presented a paper on“A

COMPARATIVE STUDY OF

ENVIRONMENTAL FRIENDLY

BIOSORBENTS FOR REMOVAL OF

FLUORIDE FROM AQUEOUS

SOLUTIONS”.He explained that

theefficiency of different biosorbents in

removal

of F from aqueous solutions was evaluated in batch system at room temperature

with considering various biosorptionparameters.Thebiosorbents can be used as

environmental friendly, effective and low cost biosorbents for removal of F from

industrial effluent containing high level of F as well as water especially in rural and

remote areas.

43

Dr. Eli Dahi, Tanzania

Dr. Eli Dahi, Defluoridation Technology

Project, Tanzania presented a paper on

“AFRICA’SU-TURN IN

DEFLUORIDATIOPOLICY: FROM

NALGONDA TO BONE CHAR.”He

demonstrated that during the recent years

Tanzania, Kenya and Ethiopia are on the

lead with respect to implementation of

defluoridation of water and they all count on

the bone char process as the process of

choice in mitigation of fluorosis in the

affected parts of the Rift valley. Some of the

experiences that led to this African U-turn in

defluoridation policy are presented.

.

44

Dr. R. Shanbhog, India

Dr. R. Shanbhog, Associate Professor Dept

of Pedodontics JSS Dental College &

Hospital JSS University Mysore,

Karnataka, Indiapresented a paper

on“EFFECT OF ORAL CARE PRODUCTS

WITH VARYING FLUORIDE

CONCENTRATIONS ON SURFACE

MICRO-HARDNESS OF FLUOROSED

ENAMEL COMPARED WITH NON

FLUORIDATED CONTROLS - AN IN-

VITRO STUDY.” He explained thatCPP-

ACPF is more effective in increasing the surface micro-hardness of fluorosed enamel

followed by 1400 ppm fluoridated dentifrice, 1000 ppm fluoridated dentifrice, non-

fluoridated dentifrice and theobromine containing dentifrice.

45

POSTER PRESENTATIONS

POSTER SESSION - I

Theme: BIOLOGICAL AND MOLECULAR ASPECTS OF FLUOROSIS

Date:10.11.2016 Time: 10.00 am to 12.00Noon Venue:Gopalan Block Lounge

Sl.

No.

Name Title Poster

No.

1. MoutushiMandi Sodium fluoride inducedalterations in the

reproductive structures of drosophila melanogaster

MBP2

2. Salma Khatun Sodium fluoride: it‟s effect on larval and adult

behavior in drosophila melanogaster

MBP3

3. ArshiIram Effect of fluoride stress on morphology and enzyme

activity ofabelmoschusesculentusseedlings

MBP4

4. MahaboobBasha P Fluoride aggravates the diabetic induced

reproductive toxicity in maleswiss mice: protective

role of ginseng and banaba

MBP5

5. Shinto Francis

Thekkudan

Voriconazole induced skeletal fluorosis in an

allogenic hematopoietic stem cell transplant

recipient

MBP6

6. GaminiSahu Genetic damage index due to chronic exposure of

arsenic and fluoride and their interaction in Asian

catfish Clariasbatrachus

MBP7

7. F Yur The effects of resveratrol on apoptosis and

oxidative DNA damage in liver and kidney tissues of

rats with experimental fluorosis

MBP9

8. VandanaPatil Influence of sodium fluoride on thyroid gland in

albino rat

MBP10

9. Dushyant Singh

Chauhan

Fluoride induced alteration in hypothalamic

testicular axis hormones and deterioration in

antioxidants status in fluorotic patients

MBP12

10. RuchiKhedia Effect of fluoride on seed germination and seedling

growth of vignaradiata

MBP13

46

POSTER SESSION – II

Theme: EPIDEMIOLOGY OF FLUOROSIS

Date: 10.11.2016 Time: 14.00-16.00hrs Venue:Gopalan Block Lounge

Sl.

No.

Name Title Poster

No.

1. Prof.UshaM.

Khandale

Prevalence of dental fluorosis in jivati tehsil of

chandrapur district

EP1

2. Dr.Nuzhat Sultana Prevalence and risk factors of fluorosis among

urban and rural population of Aurangabad

District

EP2

3 S.Dobaradaran Daily fluoride intake in bushehr port, Iran based

on drinking water consumption prepared by

household desalinators

EP8

4. A.Meghe Skeletal fluorosis and dental fluorosis in

endemic areas of fluorosis in central India

EP10

5. MsMinakshiArora, Increasing fluoride in ground water: a

perspective & (role of water resources

management)

EP12

6. MahaboobBasha P Extent of thyroid derangements in fluoride

endemic children of ChikballapurDistrict, India:

a cumulative study

EP13

7. B Ramesh Fluoride levels in Manair river water and

ground water in selected villages of

KarimnagarDistrict in Telangana, India

EP14

8. Naveen Kumar

Boiroju

Association of dental caries and dental

fluorosis with nutritional status

EP15

9. Vidyavati Ugran1 Possible ground water fluoride contamination in

Vijayapura District (Karnataka) - it‟s health

impact on rural population

EP16

10. SuneethaSapur Fluorosis and stunting: some new evidences

from India

EP19

11. Dr VK Gupta Prevalence of dental fluorosis among primary

school children in rural areas of Lucknow

EP24

12. K. Umamaheshwar A view on the fluoride levels in ground water

and foods cultivated in PrakasamDistrict, AP,

India

EP25

47

POSTER SESSION – III Theme: MITIGATION OF FLUOROSIS

Date: 10-11-2016 Time: 10.00-12.00hrs Venue: Gopalan Block Lounge

Sl.

No.

Name Title Poster

No.

1. MoumitaGouraie Moringa leaf-based biochar for mitigation of

fluoride menace in Odisha

MP1

2. S Dobaradaran The role of decentralized municipal

desalination plants in removal of fluoride from

drinking water: A case study in Bushehr, Iran

MP4

3. S Dobaradaran Fluoride level and fluoride to chloride ratio in

the ballast water in commercial ships entering

bushehr port, along the persian gulf

MP5

4. S Dobaradaran Isotherm and kinetic studies on fluoride

biosorption from aqueous solution by using

cuttlebone obtained from the persian gulf

MP6

5. S Dobaradaran Fluoride content of the persian popular herbal

distillates

MP7

6. S Dobaradaran Biosorption of fluoride from aqueous

phaseontoprosopis cineraria:evaluation of

biosorption kinetics and isotherms

MP8

7. S Dobaradaran1 Biosorption of fluoride from aqueous

phaseontosyzygiumcumini:evaluation of

biosorption kinetics and isotherms

MP9

8. S Dobaradaran Biosorption of fluoride from aqueous

phasebyziziphus leaf: evaluation of biosorption

kinetics and isotherms

MP10

9. M. Raghavendra Influence of arthrospiraplatensis as a food

supplementagainst sodium fluoride induced

toxicity on soft tissues (heart, liver and kidney)

and bone

MP12

10. AnadiGayen Assessment of fluoride contamination and

mitigation in consolidated aquifers,

BirbhumDistrict, West Bengal, India

MP13

11. ShettyPrernaShreepa

thi

Effect of two dentifrices with different fluoride

concentrations on streptococcus mutans and

lactobaccilus acidophilus – an in-vitro study

MP14

12. Sarasadathosseini Modified eggshell powder as an adsorbent for

removal of fluoride from aqueous solution

MP16

13. MangalaThakare Histological changes in ovary of rat exposed to

sodium fluoride and amelioration through

tamarind seed powder (tsp)

MP20

14. NidhiRana

Patiala

Potentiometric analysis of fluoride content in

skeletal muscles of fluorosed rats by using

ion – selective electrode

MP21

15. K.S.L.Ramya Krishna Potential of Bacillus subtilis for fluoride

removal from aqueous solutions

MP23

48

49

NilouferChinoy award Distribution

NilouferChinoy award winners

Oral

I prize - Dr. Shivananad Reddy

II Prize - Ms. SonaliDhawas

50

III Prize - Ms. S. Gupta

51

Poster

I Prize - Mr. DushyanthChauhan

II Prize - Ms. MoumitaGouriae

52

III Prize - Ms. S.M. Saumya

53

PANEL DISCUSSION

The Panel discussion was held at 4.00 -6.00 pm on 10th November 2016 during the 33rd

Conference of the International Society for Fluoride Research. The subject ofPanel

Discussion was“Intervention Strategies for Fluorosis Mitigation and policies” The

members of the panel were

Program Coordinator - Dr. Raja Reddy (Neurosurgeon and Former Director,

Nizams Institute of Medical sciences , Hyderabad )

Dr. A.K. Susheela (Executive Director of India‟s Fluorosis Research and Rural

Development Foundation, Delhi), -

Dr. A.S. Narayana, former Prof. Niloufer Hospital, Hyderabad and Padmasri awardee

and Dental Surgeon

Dr. Eli Dahi, Professor of Environmental Engineering Resident in Tanzania and Principal of

the Defluoridation Technology Project, Tanzania,

Dr.SunderRajan Krishnan -

PradeepSaxena, Additional Dy.Director General (Nutrition & IDD Cell), Directorate General

of Health Services, Ministry of Health & Family Welfare (Govt of India), New Delhi.

Dr. Arjun L. Khandare- Scientist F and Organizing secretary of ISFR

Educating people regarding importance of safe drinking water and hazards of

excessive fluoride in drinking water.

Health education activities like health talks, lectures, health screening camps,

demonstration of defluoridation techniques etc.

Multi sectoral approach: Involvement of public health dentist along with PWD, Public

Health Engineering Department, Chemists, Local Governing bodies such as

municipal corporation, Water Department etc.

Community participation

Establishment of water fluoride testing laboratories in rural areas in chemistry

laboratories of local colleges in that area

Establishing of a data base on fluoride levels in drinking water for entire country

Motivating people to adapt safe drinking water and food practices where needed

Follow up of the services provide

Publish newsletters books, folders, pamphlets

Develop website and mobile app.

The activation requires efforts from Ministry of Health, Environment in collaboration

with State Government. Therefore the time has come that Government takes this as

a major concern and intervention at the time which is appropriate.

54

The members of Panel discussion discussed on the following topics.

Program Coordinator - Dr. Raja Reddy

Fluorosis: Indian Prospective - Dr. A.K.Susheela

Dental Fluorosis and Impact - Dr. A.S. Narayana

International Agencies and Fluorosis - Dr. Eli Dahi

Role of NGO‟s in Identifying Fluorosis - Dr. Sunder Rajan Krishnan

View of counting fluorosis - Dr. PradeepSaxena

Presentation of Policy Papers - Dr. Arjun L Khandare.

GENERAL BODY MEETING

55

Photo

General Body meeting

56

GALA DINNER

The Gala dinner was organized on 10-11-2016 at Jubilee Hills International Centre

VALEDICTORY SESSION

57

LIST OF DELEGATES for the XXXIII Conference of the International Society for

Fluoride Research

Oral

1. Dr. S.L. Choubisa

2. Dr. Kenji Akiniwa,

3. Dr. Maya Ramesh

4. Dr. Sumedha Roy

5. Dr. SandeepTripathi

6. Dr. A. Ghosh

7. Dr. M Tsunoda,

8. Dr. P MahaboobBasha

9. Dr. Arjun L Khandare

10. Dr. Semiha DEDE

11. Dr. Lakshmi KanthanPannerselvam

12. K. Sudhakar,

13. M. Nageshwar

14. S Gupta

15. SonaliDhawas

16. Dr. Shivanand Reddy

17. Nisith Kumar Mondal

18. A.K. Susheela,

19. Doug Cragoe

20. Chowdappa,

21. Li Dasheng,

22. Amir HosseinMahvi

23. P. Saxena,

24. Gayen,

25. PandithMadhnure

26. P.D. Sreedevi

27. Kanagaraj Vishnu Vignesh,

28. SrinivasChekuri

29. A.G.S. Reddy,

30. A.S. Narayana,

31. Sunderrajan Krishnan

32. PerumalEkambaram

33. VarshaDhurvey

34. JitendraIngole

35. S Dobaradaran

36. Eli Dahi

37. R Shanbhog

Poster

1. MoutushiMandi

2. Salma Khatun

3. ArshiIram

4. Shinto Francis Thekkudan

5. GaminiSahu

6. F Yur

7. VandanaPatil

8. Dushyant Singh Chauhan

9. RuchiKhedia

10. Prof. Usha M. Khandale

11. Dr. Nuzhat Sultana

12. S. Dobaradaran

13. A.Meghe

14. MsMinakshiArora,

15. MahaboobBasha P

16. B Ramesh

17. Naveen Kumar Boiroju

18. VidyavatiUgran

19. SuneethaSapur

20. Dr VK Gupta

21. K. Umamaheshwar

22. MoumitaGouraie

23. M. Raghavendra

24. AnadiGayen

25. ShettyPrernaShreepathi

26. SarasadatHosseini

27. MangalaThakare

28. NidhiRana Patiala

29. K.S.L.Ramya Krishna

58

Participants

1. Amar Rathi

2. Ashok Tukaram

3. Jingupta Ashok Gachche

4. Dr.PotdarPralhadSureshrao

5. AuqifIrfan

6. DhanduSrinivas

7. GarimaMathur

8. Mr. Karan DevJamwal

9. KishoriLalVerma

10. Mabel Varghese

11. Mahendra Kumar Jaiswal

12. Devendra Kumar Chaudhary

13. Mahesh Mittal

14. Manish Kumar

15. Ajay Choudhary

16. Manish Soni

17. Satish Chand Gupta

18. JetendraHarchandani

19. Arvind Kumar Jaiswal

20. Arvind Kumar Meena

21. N.V. SrinivasRao

22. Shankar Babu

23. Sadguru Prasad

24. Bimal Prasad Pandia

25. K.Subhash

26. Avinash Krishnamurthy

27. Ghanshyam Sheet

28. Soujanya Kumar

29. RabindraNath Jena

30. Kesar Singh

31. A.B.Paul

32. DharaniSaikia

33. ArvindSinghj

34. RajnarayanIndu

35. Sunderrajan Krishnan

36. VikasRatanjee

37. SachinVani

38. KalpanaBilwal

39. Kiran Kumar

40. Shreyas .S

41. MoumitaGorai

42. Dr.Sukumar Shiva Charan

43. DibyenduDutta

44. MahasinMandal

45. ParthaSarathiKarmakar

46. ShailajaPatilDr

47. JitendraRajendra

48. RamyaKrishn

49. A K.S.L.

50. Mani Pagidipalli

51. Rama Mohan Reddy T

52. RaghuveerYadav P.

53. Monica Singh

54. RajaniGodara

55. Santosh Kumar Nagar

56. PriyaKalra

57. SapnaChaudhary

58. Devendra Sharma

59. Deepak Chaudhary

60. Sunil Kumar Bishnot

61. MeenuKumari

62. A.RajeshDr

63. B.Bhavani Prasad Dr

64. VijayaSarathiDr

65. K.Vamshi Krishna Dr

66. Dr.M.Lakshmi Surya Prabha

67. Dr.Sofia Noor

68. Dr.S.VijayaKumari

69. Dr.S.Prabhavathi

70. Dr.P.Kalyani

71. Dr.B.SivaGopal

72. Dr.K.ShanthaKumari

73. Dr.U.Venkateswarlu

74. Ratan Singh Mangawa

75. HiraLalTabiyar

76. Shruthi

77. K.Deepika

78. G.Shwetha

79. G.Soumya

59

Conference in Press

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66

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