Improving Cancer Outcomes for African Americans

Update for RTOG in Tampa

Feb 2, 2007

Patrick D. Maguire, MD

New Hanover Regional (NHRMC)

Update for NHRMCFeb 2, 2007

I. Radiotherapy (RT) Clinical Trials

II. Publications

III. Partnership & Telesynergy

IV. Patient Navigation & Outreach

RT Clinical Trials at NHRMC

CALGB 30407 – NSCLC

RTOG 0214 – PCI, Advanced NSCLC

RTOG 9804 – Good Risk DCIS (closed)

NSABP-B35 – Tam vs. AI, DCIS (closed)

CALGB 99809 – B + EB, Prostate (closed)

RTOG 0232 – B + EB, Prostate

RTOG 9811 – Anus (closed)

RT Clinical Trialsat NHMRC

S – screened & eligible

E – enrolled

U – underserved (AA &/or poor)

RT Clinical Trials Accrual 2006

Trial S E U

NSCLC 8 3 0

PCI, NSCLC 5 0(2 pend) 0

DCIS, 9804 3 1 0

DCIS, B35 9 2 1

RT Clinical TrialsAccrual 2006

Trial S E U

Prostate, 0232 7 1(2pend) 1

H&N, Z0204 12 11 2

RT Clinical Trial Accrual

S EU

2003-05 60 27 122006 44 18 4

Total 104 45 16

Publications: ManuscriptsMaguire, Meyerson, Neal, et al, Toxic Cure: hyperfractionated radiotherapy with concurrent cisplatin and fluorouracil for stage III and IVa head and neck cancer in the community. IJROBP 58: 698-704, 2004.Hamann, Kotwall, & Maguire, The role of an AHEC in developing a model program to reduce cancer disparities. National AHEC Bulletin XXI: 39-40, 2005.Johnson, Race, health, and anti-white prejudice: the influence of chronic and temporary accessibility of anti-white stereotypes on black healthcare responses. J Person Soc Psych, manuscript under review.Hamann & Bost, Black-white differences in the influence of cancer experiences on religious beliefs and healthcare satisfaction. Manuscript in preparation.

Publications: AbstractsHamann, Maguire, Bost, et al. Interactions of race, cancer knowledge and beliefs, religious beliefs, and perceived racism an cancer treatment decisions. ASTRO, Denver, 10/05Hamann, Bost, Johnson, et al. Measuring the influence of cultural and social factors on cancer treatment decisions. Am Eval Assoc, Toronto, 10/05Bost & Hamann. Effects of cancer on cultural and social beliefs. Intercultural Cancer Council, Washington DC, 4/06Maguire & Rosenman. Bridging academic and community radiation oncology treatment planning. Am Telemed Assoc, San Diego, 5/06Maguire & Honaker. A Year of Telesynergy in Southeastern North Carolina. Am Telemed Assoc, San Diego, 5/06.

Publications: Abstracts

Hamann MS, Johnson J, Maguire PD, Effects of Cancer on Cultural Beliefs. ASTRO, Philadelphia, 10/06

Maguire PD, Neal CR, Menon RP, et al. Prostate Cancer in Southeastern North Carolina: It’s Not All Black & White. ASTRO, Philadelphia, 10/06

Partnership with UNC-CH& Telesynergy

Relationship solid; visits Q4-6 months

Telesynergy IMRT planning (infrequent)H&N Tumor Board -Qwk

ZCC 00204 Trial – complete soon!

Cyberknife – trials??

Patient Navigation & Outreach 2006

Navigator - LaSonia MelvinAsst Navigator – Ursula Wilson

Patients Navigated: 2006 = 78 Total = 126

Outreach Sessions: 2006 = 28 Total = 53