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Improved outcomes and lower costs.

Improved outcomes and lower costs.. Drugs of abuse produce their effects by altering brain chemistry and structure. Neurotransmitters and associated

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Page 1: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Improved outcomes and lower costs.

Page 2: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Drugs of abuse produce their effects by altering brain chemistry and structure.

Neurotransmitters and associated receptors responsible for everyday functions are altered by the consumption of drugs.

When the drug being abused is an opiate, these changes can be very long lasting.

Page 3: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Heroin (opiate) addiction is a disease – a “metabolic disease” – of the brain with resultant behaviors of “drug hunger” and drug self-administration, despite negative consequences to self and others. Heroinaddiction is not simply a criminal behavior or due alone to antisocial personality or some other personality disorder.

(Dole, Nyswander and Kreek, 1966, 2006)

Page 4: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated
Page 5: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

After decades of research and clinical experience and after hundreds of peer

reviewed studies in scholarly journals the evidence is clear that the best clinical

outcomes for the chronic long-term opiate addict are achieved when addiction medicines are used as part of a comprehensive approach

to treatment. This is particularly true if the measure of success is long term abstinence

from illicit opiates.

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Page 6: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

When a provider (or treatment modality) claims to have a high degree of success in treating chronic, long-term, opiate addiction how can I decide if I should believe them?

Page 7: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

What not to believe:

•Anecdote•Testimonials & Rallies •Almost anything which begins ….”I can tell you from my personal experience…”.•So-called “data” which is self-generated and which has not been subject to academic and/or peer review, and which has not been published in respected scientific journals.

Page 8: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Real proof consists of:

•Peer-reviewed outcome studies published in scholarly journals.

•Repeated outcome studies by a wide-range of scientists over time which point to a continued and repeated result. Not “One and done”.

• Medication Assisted Treatment for opiate addiction meets this standard!

Page 9: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

The National Institutes on Health in 1997 concluded that Methadone “…combined with attention to medical, psychiatric, and socioeconomic issues, as well as drug counseling, has the highest probability of being effective…” in the treatment of opiate addiction.

Page 10: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Two Recent Studies in Support of Medication Assisted Treatment

•Assessing the Evidence: Medication Assisted Treatment with Methadone

•Assessing the Evidence: Medication Assisted Treatment with Buprenorphine

Page 11: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

To Find All Three Studies Go To:

www.compa-ny.org

Once on the website go to the “News” section and find each study under the heading “Research in Support of Medication Assisted Treatment”.

Page 12: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Number of patients currently in treatment:Number of patients currently in treatment:

◦ 212,000 (USA)212,000 (USA)◦ >500,000 (worldwide)>500,000 (worldwide)

Methadone is a medication: Methadone is a medication: used in the used in the detoxification & maintenance treatment of opioid detoxification & maintenance treatment of opioid addiction in conjunction addiction in conjunction with the appropriate with the appropriate social and medical servicessocial and medical services

Efficacy in “good” treatment programs Efficacy in “good” treatment programs using adequate doses (80 to 150mg/d):using adequate doses (80 to 150mg/d):◦ Voluntary retention in treatment (1+ year) = 50 – Voluntary retention in treatment (1+ year) = 50 –

80%80%◦ Continuing use of illicit heroin = 5 – 20%Continuing use of illicit heroin = 5 – 20%

Page 13: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

OTP Oversight & Regulation

•SAMHSA•DEA•OASAS•NYS DOH•LGUs

Page 14: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

What Services Can You Expect an OTP to

Provide?

Page 15: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Assessment & Intake

•Determine if patient is appropriate for OTP treatment (possible referral)•Intake Physical•Individual Treatment Plan (based on patient goals, not “cookie-cutter”

Page 16: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Medication:

•Methadone*• Suboxone (a.k.a. Buprenorphine)**• Vivitrol**

•Also – An important distinction between dispensing and prescribing.

* Provided by all OTPs** Provided by some OTPs

Page 17: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Counseling:

•Individual (brief & longer)

•Group

• As called for by individual treatment plan

Page 18: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Harm Reduction Interventions:

•HIV•HEP C•STDs

Page 19: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Services Provided by Some OTPs:

•Primary Care•Alternative to Inpatient Detox•Directly Observed Therapy•Social Service & Criminal Justice Supports

Page 20: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Typical Benefits of OTP Treatment:

•Retention in treatment•Reduction or elimination of illicit opiate use•Reduction or elimination of problematic secondary substance use•Reduction in rates of contracting both HIV and Hepatitis C•Reduction in rates of transmitting HIV, STDs, and Hepatitis C to others•Reduction in the rates of criminal behavior•Reduction in the rate of incarceration and re-incarceration•Reduction in overdose deaths•Reduction in both number and duration of hospital inpatient stays

Page 21: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Benefits of OTP Treatment (continued):

•Improvement in overall health (especially in pregnant women)•Improved engagement in primary care•Improvement in housing•Improvement in employment / productive engagement

Page 22: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Even More Benefits

•Lowest cost per successful outcome• Can most often be done in an outpatient

setting•Least disruptive to normal patient life – family & work responsibilities

Page 23: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

With the amazing success rate of medication assisted treatment why isn’t it being used

more widely?

Why does there continue to be resistance to this treatment?

Page 24: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Overcome “Data Resistance” (hiding from evidence).

Urgent need for good science to triumph over… – – SPAMSPAM – – Stigma, Prejudice, And “MythUnderstandings.”

Page 25: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Methadone was invented by the Nazis as a form of “chemical handcuffs”. As proof people say an early name for the drug “Dolophine” was a tribute to Adolf Hitler.

Page 26: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Methadone was invented in 1937 by the German pharmaceutical company IG Farben prior to World War II as a pain killer.

Beyond initial laboratory testing it was never used in Nazi Germany.

At the end of the war Eli Lilly obtained all the IG Farben facilities and patents and named the drug Dolophine as a combination of the Latin word dolor (pain) and the French word fin (end).

Page 27: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Patients on Methadone are getting high from the drug and it’s just substituting one drug for another.

Page 28: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

When a patient is properly stabilized on Methadone there is no “high”.

The drug is slow acting and it takes more than24 hours for the drug to be fully metabolized.

Virtually all drugs which produce a “high” are fast acting and achieve high levels in the blood stream quickly.

Methadone is not just replacing one drug for another since Methadone treats an imbalance which has been created in the brain from the extended use of short acting drugs like heroin.

Page 29: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Methadone patients are sedated, behave like “zombies” and are said to be “on the nod”. Thus they are incapable of productive engagement like work or school, and they should not be allowed to drive a car.

Page 30: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Once a patient is stabilized on Methadone there is no sedation or cognitive imparement.

There is no reason a Methadone patient should not be allowed to drive a car.

Page 31: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Methadone is harder to kick that heroin.

Page 32: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Once the brain has been altered by long term opiate addiction it is very difficult for many patients to achieve a “drug free” state without the use of addiction medicines.

Transitioning from Methadone to a “drug free” state is no more problematic than transitioning from illicit opiate addiction to a drug free state.

Page 33: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Methadone rots your bones, and produces a number of other negative Physical health consequences.

Page 34: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Just the opposite is true. The drug itself does no harm when taken correctly.

The patient in Methadone treatment pays more attention to their physical health and well being since they are no longer preoccupied by drug seeking behavior.

The result is a dramatic improvement in overall health.

Page 35: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Methadone is unsafe. This is proven by the fact that there has been a dramatic increase in Methadone related deaths and Methadone overdoses.

Page 36: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Methadone (like all opiates) can suppress respiration. Until an opiate tolerance is established a sufficient dose of Methadone can cause serious illness and death.

A GAO (General Accounting Office) report on Methadone deaths had two major finding:◦ Because of a lack of standardization in how deaths are

reported, a death may be called “Methadone related” if there was any Methadone in the post-mortem toxicology report. This does not prove Methadone was the cause of death.

Page 37: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

The vast majority of true Methadone overdose deaths involved patients who were prescribed Methadone for home use for pain management.

Patients were not properly informed of the dangers of the medication, or failed to use the drug as prescribed or to store it safely.

In very few cases was death linked to the use of Methadone for the purposes of opiate addiction management.

Page 38: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Methadone is a “crutch” for people too weak to go drug free.

Page 39: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

The physical changes in brain chemistry have nothing to do with strength of will.

Once addiction has occurred and the brain chemistry and physiology has been altered the brain will constantly seek an opiate drug to address this craving.

Addiction medication (Methadone, Buprenorphine, & Vivitrol) resolves this physical craving and dramatically reduces the likelihood of relapse to illicit opiate use.

Page 40: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Using Addiction Medicines is Against our Philosophy

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Page 41: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Etymology of “Philosophy”

Philo - loving

Sophia - wisdom

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Page 42: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

How is it possible to love wisdom and reject science?

Page 43: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Where can I find an OASAS licensed OTP near me?

Page 44: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

Go to the OASAS Website:

www.oasas.ny.gov/providerdirectory

•Click on “Treatment Providers”, then •Under “Provider Type” scroll down to “Methadone Treatment” *

* Of course it should say “Opioid Treatment Programs”!

Page 45: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated

For more information about Opioid Treatment & Opioid Treatment Programs, contact:

Allegra SchorrPresident COMPA (Committee of Methadone Program Administrators of New York State Inc.)911 Central Avenue, #322Albany, NY 12206

[email protected]

Page 46: Improved outcomes and lower costs..  Drugs of abuse produce their effects by altering brain chemistry and structure.  Neurotransmitters and associated