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Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John Webster

Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

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Page 1: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Improved Fine Needle Aspiration Biopsy

Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal MarshekClient: Dr. Elizabeth BurnsideAdvisor: John Webster

Page 2: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Problem Statement

GOAL: To modify the needle used during a Fine Needle Aspiration (FNA) procedure. The modification should not drastically change the FNA procedure and still increase the amount of tissue removed for cytological testing. It should also minimize the time (by collecting an adequate sample size on the first attempt) and discomfort caused to the patient during the procedure.

Page 3: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

What is FNA?

Technique used to extract cells; no incision neededSeveral insertions are usually required to ensure an adequate sample sizeSamples are sent to pathologist to be analyzed National Breast Cancer Center,

http://www.NBCC.org

Page 4: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Fine Needle Aspiration (FNA)

A.D.A.M., http://www.adam.com

Page 5: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Product Design Specifications

Removes adequate number of cells for diagnosis. Should not cause more discomfort than current FNA procedure. Constrained to standard 20-25-gauge needle, client prefers 23-gauge.

Page 6: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Micro-Drill Bit Insert

Draws cells up drill fluting into needleFits inside 23-gauge needle Outer Diameter: 0.0145 inches

Currently too short Length: approximately 1 inch Needs to be lengthened

Easy to obtain

Page 7: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Needle Manufacturer

Drill Bit ContactsResponsesWork in Progress

Page 8: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

ME Shop/Process

WeldingSolderingBrazing

Page 9: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Sample Size

Comparison Old vs. New Techniques

Histological analysisCell Quantification

Page 10: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Testing

Tissues AvailableFuture Testing

Page 11: Improved Fine Needle Aspiration Biopsy Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal Marshek Client: Dr. Elizabeth Burnside Advisor: John

Future Work

Prototype developmentResearch into appropriate materials to be used (stainless steel, Co-Cr, Ti)Develop protocol for quantifying testingTest on tissue similar to breast tissueQuantify sample needed for cytological evaluation