Immunology & Medical Microbiology 1

Immunology & Medical MicrobiologyDegree Offered

• Bachelor of Science

IntroductionEvery day of our lives, we are exposed to microbes such as bacteria, viruses, and parasites. For the most part we suffer no disease or symptoms fromthese organisms, and they often go un-noticed. The single system in the body that allows life to continue in the face of these assaults is the immunesystem. The immune system is the network of cells and their biological processes that enable the body to recognize diseased cells or the invasion bymicroorganisms (bacteria, viruses, parasites, and prions) and eliminate them. The scientific discipline called Immunology is the study of this system,and Medical Microbiology is the study of the disease states induced by the invasion of microorganisms. Collectively, these two disciplines address howhumans and other mammals respond to infectious disease. These scientific disciplines have become the cornerstone for many industries - including thebiotechnology, pharmaceutical and medical and public health industries. These are all areas of particular emphasis and are being targeted for furtherdevelopment in West Virginia.

Educational ObjectivesThe Bachelor of Science degree in Immunology and Medical Microbiology will prepare students from diverse backgrounds to serve as professionalsthat are knowledgeable about the immune system of humans and other mammals, how the immune system functions, and the consequences of itsmalfunction on the health of the host. Knowledge of the immune system will be fully integrated with an excellent understanding of the diversity ofmicroorganisms that cause disease in humans and other mammals and mechanisms of disease pathogenesis. Graduates will possess the laboratoryskills and knowledge needed to assess the functional status of the immune system and to safely cultivate and identify microorganisms that causedisease in mammals. Graduates will be qualified to pursue several professional career paths in private industry, state and federal government, andacademic institutions. The degree can also provide a strong foundation to progress to advanced studies leading to a Masters or professional degree.

Relationship of the Objectives to the Mission of WVUThe Bachelor of Science degree in Immunology and Medical Microbiology directly fulfills many of the stated objectives in the Strategic Plan for WVU,the WVU Health Sciences Center and the WVU School of Medicine. It will be a financially viable, new, innovative and dynamic educational program thatprovides a unique opportunity to earn a degree in Immunology and Medical Microbiology for both in-state and out-of-state undergraduate students. Itslearner centered curriculum will integrate both classroom and hands-on laboratory experiences. Graduates of the program will provide the state of WestVirginia with a well-trained healthcare and research workforce who have the education and experience to work in a variety of occupations that requireknowledge in immunology, medical microbiology and related disciplines.

FACULTYCHAIR

• John B. Barnett - Ph.D. (University of Louisville)

ASSISTANT PROFESSORS• Mariette Barbier - Ph.D. (Universitat de les lles Balears)

• Kathy Brundage - Ph.D. (University of Pennsylvania)Technical Director of Flow Cytometry Core Facility

• Duaa Dakhlallah - Ph.D. (The Ohio State University)

• F. Heath Damron - Ph.D. (Marshall University)

• Meenal Elliott - Ph.D. (University of Alabama)

• Jennifer Franko - Ph.D. (Case Western Reserve University)

• Ivan Martinez - Ph.D. (University of Pittsburgh)

• Gordon Meares - Ph.D. (University of Alabama)

• Edwin Wan - Ph.D. (City of University of Hong Kong)

• Valerie Watson - M.S. (West Virginia University)

ASSOCIATE PROFESSORS• Tin Eubank - Ph.D. (The Ohio State University)

• Slawomir Lukomski - Ph.D. (University of Lodz, Poland)

• Karen Martin - Ph.D. (Duke University)

• Edmidio Pistilli - Ph.D.

2 Immunology & Medical Microbiology

(West Virginia University)

• Lisa Robinson - Ph.D. (Cornell University)

• Cory Robinson - Ph.D. (Miami University of Ohio)

• Rosana Schafer - Ph.D. (Temple University)

• James M. Sheil - Ph.D. (University of Kentucky)

ADJUNCT PROFESSORS• Don Beezhold - Ph.D. (University of Illinois Medical Center)

• John Noti - Ph.D. (Purdue University)

• David Weissman - M.D. (Northwestern University)

ADJUNCT ASSOCIATE PROFESSOR• David Klinke - Ph.D. (Northwestern University)

ADJUNCT ASSISTANT PROFESSORS• Stacey Anderson - Ph.D. (West Virginia Univeristy)

• Alexandra Elliott - Ph.D.

• Brett Green - Ph.D. (University of Sydney)

• Yong Qian - Ph.D. (West Virginia University)

Admission Requirements:Applicants must fulfill all requirements for admission to WVU and the IMMB program:

• ACT Math score of 26, or SAT Math score of 620, or place into Chemistry 115

• High school GPA of # 3.70

• Complete admissions information at http://admissions.wvu.edu/admissions/university-requirements

Click here to view the Suggested Plan of Study (p. 4)

GENERAL EDUCATION FOUNDATIONSPlease use this link to view a list of courses that meet each GEF requirement. (http://registrar.wvu.edu/gef)

NOTE: Some major requirements will fulfill specific GEF requirements. Please see the curriculum requirements listed below for details on which GEFsyou will need to select.

General Education Foundations

F1 - Composition & Rhetoric 3-6

ENGL 101& ENGL 102

Introduction to Composition and Rhetoricand Composition, Rhetoric, and Research

or ENGL 103 Accelerated Academic Writing

F2A/F2B - Science & Technology 4-6

F3 - Math & Quantitative Skills 3-4

F4 - Society & Connections 3

F5 - Human Inquiry & the Past 3

F6 - The Arts & Creativity 3

F7 - Global Studies & Diversity 3

F8 - Focus (may be satisfied by completion of a minor, double major, or dual degree) 9

Total Hours 31-37

Please note that not all of the GEF courses are offered at all campuses. Students should consult with their advisor or academic department regardingthe GEF course offerings available at their campus.

Degree RequirementsMinimum GPA of 2.75 is required in all coursework

First Year Studies Requirement

GEF Requirements 1, 4, 5, 6, and 7 18

Immunology & Medical Microbiology 3

IMMB 191 First-Year Seminar 1

BIOC 339 Introduction to Biochemistry 4

BIOL 115 Principles of Biology 4

BIOL 117 Introductory Physiology 4

BIOL 219 The Living Cell 4

BIOL 324 Molecular Genetics 3

Select one of the following sequences: 8

CHEM 115& CHEM 116

Fundamentals of Chemistryand Fundamentals of Chemistry

CHEM 117& CHEM 118

Principles of Chemistryand Principles of Chemistry

CHEM 233 Organic Chemistry 3

CHEM 234 Organic Chemistry 3

CHEM 235 Organic Chemistry Laboratory 1

CHEM 236 Organic Chemistry Laboratory 1

Select one of the following: 3

MATH 150 Applied Calculus

MATH 153 Calculus 1a with Precalculus

MATH 154 Calculus 1b with Precalculus

MATH 155 Calculus 1

MATH 156 Calculus 2

Select one of the following sequences: 8

PHYS 101& PHYS 102

Introductory Physicsand Introductory Physics

PHYS 111& PHYS 112

General Physicsand General Physics

STAT 211 Elementary Statistical Inference 3

or STAT 215 Introduction to Probability and Statistics

or ECON 225 Elementary Business and Economics Statistics

IMMB 150 Microbiology Colloquium 1 2

IMMB 200 Immunology Colloquium 1 2

IMMB 250 Microbiology Colloquium 2 2

IMMB 300 Immunology Colloquium 2 2

IMMB 301 Basic Medical Microbiology 4

IMMB 302 Principles of Immunobiology 3

IMMB 310 Bacterlal Pathogenesis 4

IMMB 320 Cellular Immunobiology 3

IMMB 400 Senior Colloquium 1 1

IMMB 405 Scientific Integrity 1

IMMB 410 Microbial Genetics 3

IMMB 420 Molecular Immunobiology 5

IMMB 494 Seminar 1

IMMB 450 Senior Colloquium 2 1

IMMB 460 Contemporary Issues for Majors 3

IMMB 470 Medical Virology 3

IMMB 484 Senior Thesis (fulfills Writing and Communication Skills and Capstone requirements) 3

Choose 9 credits from the following IMMB approved Electives 9

IMMB 327 Parasitology

IMMB 480 Vaccinology

IMMB 491 Professional Field Experience

IMMB 497 Research

AEM 341 General Microbiology

AEM 401 Environmental Microbiology

4 Immunology & Medical Microbiology

AEM 445& AEM 449

Food Microbiologyand Food Microbiology Lab

BIOL 302 Biometry

BIOL 310 Advanced Cellular/Molecular Biology

BIOL 315 Communicating Natural Science

BIOL 348 Neuroscience 1

BIOL 409 Biochemical Basis of Therapeutics

BIOL 413 Molecular Endocrinology

BIOL 415 Epigenetics

BIOL 418 Medical Genetics

BIOL 420 Genomics

BIOL 426 Molecular Biology of Cancer

BIOL 430 Bioinformatics

HN&F 348 Science of Food Preparation

HN&F 353 Food Service Systems Management

Total Hours 120

SUGGESTED PLAN OF STUDYFirst Year

Fall Hours Spring Hours

IMMB 191 1 ENGL 101 (GEF 1) 3

IMMB 150 2 CHEM 116 (GEF 2) 4

MATH 150 (GEF 3) 3 BIOL 117 4

CHEM 115 (GEF 8) 4 GEF 4, 5, 6, or 7 3

BIOL 115 (GEF 8) 4

GEF 4, 5, 6, or 7 3

17 14

Second Year

Fall Hours Spring Hours

CHEM 233 3 CHEM 234 3

CHEM 235 1 CHEM 236 1

BIOL 219 4 IMMB 200 2

IMMB 250 2 PHYS 102 (GEF 8) 4

PHYS 101 4 GEF 4, 5, 6, or 7 3

ENGL 102 (GEF 1) 3

17 13

Third Year

Fall Hours Spring Hours

BIOC 339 4 BIOL 324 3

IMMB 300 2 IMMB 310 4

IMMB 301 4 IMMB 320 3

IMMB 302 3 GEF 4, 5, 6, or 7 3

Elective (IMMB approved) 3 Elective (IMMB Approved) 3

16 16

Fourth Year

Fall Hours Spring Hours

STAT 211 3 IMMB 405 1

IMMB 400 1 IMMB 450 1

IMMB 410 3 IMMB 460 3

IMMB 420 5 IMMB 470 3

IMMB 494 1 IMMB 484 3

Immunology & Medical Microbiology 5

Elective (IMMB approved) 3

13 14

Total credit hours: 120

Major Learning OutcomesIMMUNOLOGY & MEDICAL MICROBIOLOGYGoal 1: The Bachelor of Science in Immunology and Medical Microbiology program is designed to provide students with a thorough understanding of thebasis of the mammalian immune system and how it functions to protect the body from infectious agents in conjunction with an in-depth knowledge andunderstanding of pathogens.

Goal 2: Students will be prepared to serve as professionals that are knowledgeable about the immune system of humans and other mammals, how theimmune system functions, and the consequences of its malfunction on the health of the host.

Goal 3: Students’ knowledge of the immune system will be fully integrated with an understanding of the diversity of microorganisms that cause diseasein humans and other mammals and mechanisms of disease pathogenesis.

Goal 4: Graduates of the program will provide a well-trained healthcare and research workforce who have the education and experience to work in avariety of occupations that require knowledge in immunology, medical microbiology, and related disciplines.

Goal 5: Graduates will possess the laboratory skills and knowledge needed to assess the functional status of the immune system and to safely cultivateand identify microorganisms that cause disease in mammals.

Goal 6: Graduates will be well-suited for various educational or career options. They will be qualified to work as immunologists or microbiologistsin many diverse fields – including biotechnology research and industry, the pharmaceutical industry, the medical industry, the public health arena,academia, and various state and federal government agencies.

Goal 7: Graduates will be well prepared for advanced graduate or professional school education and training including public health, medicine, dentistry,and pharmacy.

IMMB 150. Microbiology Colloquium 1. 2 Hours.Peer and faculty-led learning experiences to introduce students to the disciplines of immunology and medical mircobiology.

IMMB 200. Immunology Colloquium 1. 2 Hours.Peer and faculty-led learning experiences to introduce students to the discipline of immunology.

IMMB 250. Microbiology Colloquium 2. 2 Hours.PR: IMMB 150. Peer and faculty-led learning experiences to continue to introduce students to the discipline of medical microbiology.

IMMB 300. Immunology Colloquium 2. 2 Hours.PR: IMMB 200. Peer and faculty-led learning experiences to continue to introduce students to the discipline of immunology.

IMMB 301. Basic Medical Microbiology. 4 Hours.Combined lectures and laboratory exercises on the study of pathogenic microorganisms and clinical laboratoy techniques.

IMMB 302. Principles of Immunobiology. 3 Hours.Study of the basic concepts underlying the mechanisms of innate and adaptive immunity.

IMMB 310. Bacterlal Pathogenesis. 4 Hours.Pathogenic bacteiology with an emphasis on the mechanicms of pathogenesis. Topics include microbial adherence, motility, toxin production andmechanisms, and normal flora and disease.

IMMB 320. Cellular Immunobiology. 3 Hours.Emphasis on understanding the cellular elements that impact immune responses. This course builds on fundamental principles discussed in IMMB 302to address areas of current research in immunobiology.

IMMB 327. Parasitology. 2 Hours.(For medical tehnology students; other students with consent.) Study of animal parasites and disease wectors with empasis on disease manifestations,parasite biology, and laboratory diagnosis.

IMMB 350. Microbiology Colloquium 3. 2 Hours.PR: IMMB 250. Peer and faculty-led experiences to introduce students to the disciplines of medical microbiology.

IMMB 400. Senior Colloquium 1. 1 Hour.Review and discussion on current immunology and medical microbiology literarure. Seniors are required to lead one discussion session beforegraduation.

IMMB 405. Scientific Integrity. 1 Hour.Discussion and review of topics addressing fundamental issues in maintenance of scientific integrity in biomedical research.

6 Immunology & Medical Microbiology

IMMB 410. Microbial Genetics. 3 Hours.Molecular aspects of mutation, gene transfer mechanisms, genetic mapping, and genetic control using bactaria and bacteriophage systems as models.

IMMB 420. Molecular Immunobiology. 5 Hours.Study of the structure and function of the families of molecules employed by the immune system to recognize and initiate the immune response and thesignaling pathways within the cell involved in the immune system.

IMMB 450. Senior Colloquium 2. 1 Hour.Review and discussions on current immunology and medical microbiology literature. Seniors are required to lead one discussion session beforegraduation.

IMMB 460. Contemporary Issues for Majors. 3 Hours.Detailed coverage for major issues of contemporary research in immunobiology.

IMMB 470. Medical Virology. 3 Hours.Molecular biology of viruses that are important both biologically and medically. Includes a basic introduction to replication and genetics as well as currenttopics in moleclar virology.

IMMB 480. Vaccinology. 4 Hours.PR: IMMB 302 and IMMB 310 and IMMB 320 and IMMB 410 with a minimum grade of C- in each. Emphasis on understanding vaccinology in thecontexts of historical significance, vaccine models, pre-clinical to clinical development, human efficacy, and relationships with the public.

IMMB 484. Senior Thesis. 3 Hours.Essays and oral presentations by senior students covering contemporary topics in immunology and medical microbiology. Senior students are requiredto present one seminar before graduation.

IMMB 490. Teaching Practicum. 1-3 Hours.PR: Consent. Teaching practice as a tutor or assistant.

IMMB 491. Professional Field Experience. 1-18 Hours.PR: Consent. (May be repeated up to a maximum of 18 hours.) Prearranged experiential learning program, to be planned, supervised, and evaluated forcredit by faculty and field supervisors. Involves temporary placement with public or private enterprise for professional competence development.

IMMB 494. Seminar. 1-3 Hours.PR: Consent. Presentation and discussion of topics of mutual concern to students and faculty.

IMMB 496. Senior Thesis. 1-3 Hours.PR: Consent.

IMMB 497. Research. 1-6 Hours.Independent research projects.