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HarmonyImaging and Analysis for Cytogenetics
EveryDiagnosisCounts
Chromosome Analysis and FISH Diagnostics
Automated workflows, digital analysis and full integration
maximize lab efficiencies
Optimized Productivity
Diagnostic Confidence
Multi Application
Superb image quality, powerful algorithms and feature rich software ensure results accuracy
A broad sample, staining and probe menu that meets the full range of Cytogenetic demands
"Harmony doubled our lab productivity in bone marrow karyotyping and tripled our productivity in blood sample karyotyping."
Nettie Rietema, University Medical Center Groningen, NL
"Harmony allows us to view much more cells than we would with a manual microscope, which leads to more accurate and reliable FISH results. Manual FISH analysis is also tedious
and leads to technologist fatigue but Harmony never gets tired."
Dr. Yarin Hadid, Bnai Zion Medical Center
Automatic Slide Scanning
Digital Karyotyping and FISH Analysis
View, Manage and Share
Uncompromising Image QualityStart & Walkaway Scanning
Feature Rich Review & Analysis
Increased Lab Productivity
Easy Separation and Boundary Editing
Advanced Onscreen Supervisor Review
High resolution 4MP camera sensor combined with a high quality 100x immersion oil objective
Broad Staining and Sample Menu
FISH
G-Band
Spectral
Q-Band
R-Band
R-Band
Free technologist time to where their expertise is needed most
“Magic Tool” combining 12 operations in a simple mouse click
Blood Bone Marrow Amniotic Fluid CVS
CountAccurate automatic
chormosome counting
Image GalleryDisplay of all case metaphases and karyotypes
AnalyzeFast and easy chromosome indexing and classification
Chromosome CompareAll captured cells and chromosomesside by side
KaryotypeEasy separation of chromosomes
and advanced image enhancement
Aberrant IdeogramChromosomes, cells, ideograms andannotations in an image generator
Digital Chromosome Analysis
Efficiency, Precision, Versatility
Traditional Karyotyping
HarmonyBone Marrow Amnio Blood
4,532
1,548
1,352
468
624
204
Overlap ExtendSplit Combine
Saves hundreds of mouse-clicks per
karyotype!
66% Technologist Time Savings (Hours / Month)
*FDA cleared for BandView, FISHView, CEP XY, UroVysion, ALK and HER2/neu FISH
Easy Classification & Review
Image Quality Driven to the Max! Increased Diagnostic Confidence
Workflow Efficiencies for Increasing Test Volumes
Wide Application Coverage
Any Sample
Any Probe
Digital Z-Stacking
Multi Layer Display
Signal Detection
Digital FISH DiagnosticsAccuracy, Consistency, Ease-of-Use
Over 55% Time Savings (Minutes / Case)
*FDA cleared for BandView, FISHView, CEP XY, UroVysion, ALK and HER2/neu FISH
HER2/neu (Breast)
Hematology Enumeration
ALK (Lung)
Hematology Fusion
UroVysion (Bladder)
“Digital FISH analysis provides more efficient and accurate results and better patient care in comparison to traditional FISH methods.”
Liew M, Rowe L, Clement PW, Miles RR, Salama ME., J Pathol Inform. 2016
AccuracyAutomated cell/ signal detection and classification for consistent reliable results
High image quality with digital Z-stack of each cell
Cell gallery for fast and easy classification review
Multi-layer view for each signal
Real time statistics
No More Dark Room!
Harmony
Manual FISH
ALK CLL AML
45
-78% -71%
-58%
10
50
21
45
13
Quality Control of Probe AssaysCell phenotyping and signal classificationMeasurment and display of multiple cellular and signal properties
Harmony for Research Applications
Circulating Tumor Cells Immuno Fluorescence
clgFISH Successive Staining
TelomeresSperm Cells
Automatic identification of translocations and chromosomal origins
Simultaneous detection of chromosomal aberrations in one hybridization
Measurement of entire spectrum at each point
Multi-Color FISH Analysis for Result Verification
Brain Tumor Ewing Sarcoma
HiSKY Probe KitChromosome paints for human, mouse and rat
HiSKYFISH Research
Gold Standard Spectral Karyotyping
MN ScoreMicronuclei imaging, scoring and analysis for measurement of DNA damage, cytostasis and cytotoxicity
Case Data Management (CDM)
GenASIs AnyWhere™ for Remote AccessLab Connectivity Anytime, Anywhere
Review, analyze and sign off case information from any location via a secured network
Data Management and ConnectivityModern Paperless Workflow
Central Portal and Database Easily Integrates with Lab LIS
LIS Connectivity
Performance
Security
Data Integrity
HIPAA Compliant
Advanced Reporting 1D/2D Barcode Reader
Efficient
Comprehensive
Eliminates human error
Remote access,review and analysis
Supervisor easy access
Director sign off from any location
GLOBAL ACCESS
User selected Fields of View
Semi Automated
High Cellular Density
User pre-configured scanning pattern and stop criteria
Fully Automated
High Cellular Density
DensityScan™ automatic detection and ranking of Fields of View
Fully Automated
Low Cellular Density
Automated WorkflowsKaryotyping and FISH in The Same Batch
Scanning Protocols for All Probes, Samples and Preparation Techniques
Fully Automated
Patient Database
Immediate Access
Automatic Barcode Reader Unattended Scanning Oil Dispenser Image Acquisition
Onscreen Analysis Advanced Supervisor Review Customized Reporting LIS Connectivity
www.spectral-imaging.com
North AmericaApplied Spectral Imaging Inc.Tel: +1 760 929 [email protected]
HeadquartersApplied Spectral Imaging Ltd.Tel: +1 817 886 [email protected]
Manual 1 Slide 9 Slide Motorized Stage 81 Slide Tray Loader HyperSpectral 1 Slide
Microscope Support BF and FL upright
microscopes
OLYMPUS BX61, OLYMPUS
BX63, ZEISS AxioImager Z2
OLYMPUS BX61, ZEISS
AxioImager Z2
BF and FL upright
microscopes
Objectives 10x, 60x (oil), 100x (oil) OLYMPUS:
4x, 10x, 40x, 60x (oil), 100x (oil)
ZEISS:
4x, 10x, 40x (oil), 63x (oil), 100x (oil)
OLYMPUS:
4x, 10x, 40x, 60x (oil), 100x (oil)
ZEISS:
4x, 10x, 40x (oil), 63x (oil), 100x (oil)
10x, 60x (oil), 100x (oil)
Camera 4MP Monochrome 4MP Monochrome 4MP Monochrome Spectral 1.3MP
Monochrome
Slide Capacity 1 slide (Manual or
Motorized)
9 slides 81 slides PLUS 1 slide (Manual or
Motorized)
Barcode Reader Handheld 1D/2D Handheld 1D/2D Integrated 1D/2D Handheld 1D/2D
Automated Oil Dispenser
N/A Optional Integrated N/A
Dimensions [WxDxH] 28cm x 44cm x 55cm 32cm x 54cm x 67cm 100cm x 56cm x 75cm 28cm x 44cm x 85cm
Weight 16kg 42kg 100kg 20kg
DOC000349 Rev. B