Just published: Volume 25ANNUAL REVIEW OF

BIOCHEMISTRYApprox. 800 pages

CONTRIBUTORS:B. S. PlattA. MeisterJ. S. Frutonand M. J. Mycek

E. J. Bourneand R. Stephens

F. B. ShorlandC. E. CarterF. W. PutnamS. Bergstromand B. Borgstrom

W. C. Schneiderand G. Hogeboom

H. Raistrickand C. E. Stickings

S. F. Velick

H. Fraenkel-ConratH. A. ItanoE. A. Adelbergand M. Rabinovitz

J. J. Pfiffnerand 0. D. Bird

E. E. Snelland D. E. Metzler

G. W. E. Plautand J. J. Betheil

E. Kod'icekW. H. GriffithC. HeidelbergerMf. Friedman, S. 0. Byers,and S. St. George

M. HeidelbergerW. H. FishmanS. Korkes

Vols. 13, 16 to 24 also available

$7.00 postpaid (U.S.A.); $7.50 postpaid (elsewhere)

ANNUAL REVIEWS, INC.GRANT AVE., PALO ALTO, CALIFORNIA

HIGH VACUUM WORK

APIEZON®OILS, GREASES, WAXESApiezon products have therecognition of leading sci- A*IEZokentists who accord themtop preference for highvacuum work. A bulletinjust off the press describesthe physical characteristicsof a variety of special oils,greases and waxes for oil-diffusion pumps, sealing joints, stop cocks,etc. You should have a copy to augment

your store of knowledge on the subject.Mailed free; simply ask for Bulletin 43-S.

~~PERSONNEL PLACEMENT

|||||||||||POSITIONS WANTED |111111111Biochemist, Ph.D. 1952. Research experience onenzyme synthesis, drug resistance, experimentalpathology. Box 179, SCIENCE. X

Botanist, Plant Physiologist, M.A., Ph.D. sum-mer 1956, woman, Canadian, experience in lec-turing elementary botany, demonstrating biol-ogy, plant physiology. Desires teaching positionin these or related fields. Available for interviewat Storrs. Box 176, SCIENCE. 7/20, 27

Chemist; Ph.D.; 7 years as senior chemist andproduction superintendent in industry; 5 yearsas director of research, pharmaceutical company.Medical Bureau (Burneice Larson, Director),Palmolive Building, Chicago. X

138

I||||||||||||||J|||1111 POSITIONS OPEN |Clinical Investigation-Opportunity for interest-ing career dealing with new medical develop-ments of front-rank ethical pharmaceutical houselocated Midwest. Desired qualifications: Amer-ican training and licensure, background in basicresearch or Board qualified, age below 40. ApplyBox 178, SCIENCE. 7/27

(a) Faculty members in anatomy, bacteriology,chemistry, microbiology, physiology, immunol-ogy, immunochemistry, virology, ecology, mathe-matics, physics, pharmacology, microbial physi-ology. (b) Assistant director, excellentlyequipped laboratories for scientific criminal in-vestigation; Ph.D., trained in physiology, phar-macology, human anatomy, pathology. (c) Ana-lytical chemist; control department, pharmaceu-tical company; $7800; West. (d) Medical direc-tor; medical advertising agency. (e) Physicianor Ph.D. in microbiology or biochemistry;duties principally research; $12,000; West. (f)Chief biochemist affiliated university medicalschool; capable of initiating and coordinating re-search program both on clinical and basic level;$7500-$8900; South. S7-3 -Medical Bureau(Burneice Larson, Director), Palmolive Build-ing, Chicago. X

Opening for Fish and Crab Culturist withComm. of Tidewater Fisheries in Annapolis.Requires bachelor's deree in biology or bio-chemistry, and 3 years experience in fisheriesbiology work or biochemistry work; or master'sdegree and 1 year's experience. Salary $5021-$6021 with increase of $260 on or after 1 Oct.File application by 31 July with Commissionerof Personnel, 31 Light St., Baltimore 2, Md. X

SCIENCE, VOL. 124

POSITIONS WANTED 1111111111111111111CLASSIFIED: 18¢ per word, minimumcharge $3.60. Use of Box Numbercounts as 10 additional words.

COPY for classified ads must reachSCIENCE 2 weeks before date of issue(Friday of every week).

DISPLAY: Rates listed below - nocharge for Box Number. Monthlyinvoices will be sent on a chargeaccount basis-provided that satis-factory credit is established.

Single insertion $22.00 per Inch13 times in 1 year 21.00 per Inch26 times in 1 year 20.00 per Inch52 times in 1 year 19.00 per inch

For PROOFS on display ads, copy mustreach SCIENCE 4 weeks before dateof issue (Friday of every week).

Pathologist, 40. Certified clinical and anatomicalpathology. Associate Professor. Extensive surgi-cal pathology and cancer research. More than 50publications. Pennsylvania, Florida, Californialicenses. Category IV. Box 161, SCIENCE.

7/6, 13, 20

Zoologist, Ph.D., Harvard 1954. Research andteaching, histology, parasitology, invertebrateand vertebrate anatomy. Available 1 September.Box 172, SCIENCE. 7/20

IIIIIlIIIliIIIIIIIIIPO lPOSIMIONS OPENIIIIIIIIIIAIII VII VIII

Assistant Professor of Anatomy: Ph.D. orM.D. State medical school, Southwest. Open-ing for histological-embryologist with researchinterests. Ample time and facilities for investi-gative work. Salary dependent on past record.Box 162, SCIENCE. X

Bacteriological Technician, interesting work.40-hour week, no night calls. Pleasant environ-ment, air-conditioned. Write Personnel, Chil-dren's Hospital, Cincinnati 29, Ohio. 7/6, 13, 20

Instructorship for 1956-57 in a small liberal artscollege in central New York. To teach generalbotany and general bacteriology and assist withanother course. Box 115, SCIENCE. 7/20

-

lw_-Ivoz

LL

ERSONNELILACEMENU

Ph.D. with Research Background in Agricul-ture, B.S. in entomology or plant pathology; tohead research with privately owned agriculturaichemical concern. Give biographical sketch.Salary open. P.O. Box 727, Salinas, Calif.

7/13, 20, 27

Pharmacologist-Research division of prominentpharmaceutical manufacturer has opening forpharmacologist to conduct research on the phar-macodynamic action of drugs. Salary commen-surate with training, experience, and ability.Eastern location. In reply state age, education,experience, and salary desired. Our staff knowsof this advertisement. Box 174, SCIENCE.

7/20, 27; 8/3

I

Statisticians for statistical group at atomic powerlaboratory. Will serve as consultants to engi-neers, physicists, chemists, and metallurgists inthe design of experiments. Requires a minimumeduational level of master of science degree witha broad theoretical background in statistics.Write: Mr. A. M. Johnston, Dept. C-39, West-inghouse Bettis Plant, P.O. Box 1468, Pitts-burgh 30, Pa. X

Writers, for free lance writing in anthropology,biology, geology, and natural history. Ph.D. orequivalent training. Experienced writers only.Send background details. Box 158, SCIENCE.

7/6, 13, 20

FIhe MARKET PLACEABOOKS * SERVICES * SUPPLIES * EQUIPMENT

JJJ111jfJ11JfBOOKSAND MAGAZINES|||||||||||||

PURN E. .. Sets and runs, foreignSCIENTIFICand domestic. Entire

PERIODICALS libraries and smallerand BOOK S collections wanted.

WALTER Z. JOHNSON, INC.125 E. 23rd St., New York 10, N. Y.

Your sets and files ofscientific journals

are needed by our library and institutional cus-tomers. Please send us lists and description ofperiodical files you are willing to sell at high mar-ket prices. Write Dept. A3S, J. S. CANNER, Inc.

Boston 19, Massachusetts

SCIENTIFIC JOURNALS WANTEDSets, Runs and Volumes bought at top prices.

Your wants supplied fromour Back Files of over 3,000,000 periodicals.Abrahams Magazine Service; N. Y. 3, N. Y.

| SUPPLIES AND EQUIPMENT ||||||

ALBINO ATSOur mass production methods insuregreatest uniformity and consistency

Price list on requestDAN ROLFSMEYER CO. Ph. 6-6149

Route 3, Syen. Road, Madison, Wisconsin

20 JULY 1956

|||||||||SUPPLIES AND EQUIPMENT ||||||I| 1|||||||SUPPLIES AND EQUIPMENT|||||||

CONSISTENT RATS & MICE

BUDD MT. RODENT FARMCHESTER, N. 1.

Breeders of a recognized strainof Wistar rats and W.S. mice

l

"Wanted: A second hand, medium quartz orlarge Littrow spectrograph (Bausch and Lombor Hilger), if available at reasonable cost, tobe used for college instruction. Please reply toBert L. Vallee, M.D., Peter Bent Brigham Hos-pital, Boston, Mass."

SEND FOR DETAILS

ON THE NEW,ULTRA-COMPACT

GME-LARDY WARBURGAPPARATUS

* "From the hand oj

albino rats Shtoerearch"Hypophysectoemzed

*Descendants of the -Y Ii1SpragW-Daey ead

Wistar Strains0

HENRY L. FOSTER, D.V.M.President and Director

THE CHARLES RIVER BREEDING LABS.Dept. B, Wilmington, Mass.

STAINS-GURR'S-INDICATORSFREE PRICE LIST

ESBE LABORATORY SUPPLIES459 Bloor St., W. Toronto, Canada

Jj1111fj1 PROFESSIONAL SERVICES !lhilIII

Projects, Consultation, and Pro.AW ^ duction Control Services In

*ESEHI Biochemistry, Chemistry, Bacteri-EfOIRIDATN ology, Toxicology- Insecticide

Testing and Screening.

oTRUSDAILLaboratories, Rop W. TrndlaIl, Ph.D.,

Inc. Presdentc. E. P. Jelrys, Ph.D.,Chemists-Engineers Technleal Direeter

Bacteriologists

LaWall & HarrissonW.S. 1921W*d SL, PMbidb Pa

*

I

139

MY -

Openings at B.S., M.S., and Ph.D. levels fortheoretical and experimental physicists interestedin reactor physics. Atomic power research labora-tory offers wide variety of challenging work.WTrite: Mr. A. M. Johnston, Dept. C-38, West-inghouse Bettis Plant, P.O. Box 1468, Pitts-burgh 30, Pa. X

Spectroscopist Analyst: Research analytical lab-oratory of East Coast pharmaceutical manufac-turer seeks Ph.D. in chemistry; 25-35, withseveral years' postdoctoral experience, qualifiedin both ultraviolet and infrared spectroscopy andpreferably with experience in chemical analysis.Liberal benefit program. Send complete personaldata. Box 173, SCIENCE. 7/20, 27; 8/3

DISPLAY: Rates listed below - nocharge for Box Number. Monthlyinvoices will be sent on a chargeaccount basis-provided that satis-factory credit is established.

Single insertion $22.00 per inch13 times in 1 year 21.00 per inch26 times in 1 year 20.00 per inch52 times in 1 year 19.00 per inch

For PROOFS on display ads, copy mustreach SCIENCE 4 weeks before dateof issue (Friday of every week).

E.

HOLTZMAN RAT CO.Proven excellent incancer research

Rt. 4, Box 205 Madison 4, Wisc.Phone Alpine 6-5573

m mommaI..- .............. I., .1 ....... -1 ........

POSITIONS OPEN

.........

II

a

t

PO-SITIONS OPEN IllOSITIONS OP&N111111111111

GET YOUR ADVANCEi COPY

of the General Program-Directoryof the AAAS New York Meeting

by first class mail - early in December

The General Program-Directory of the 123rd Meeting of the AAAS in New York City, Dec.26-31, 1956, will be available to anyone, at cost, within the first week in December-whether he canattend the Meeting or not. You will want the General Program-Directory for your reference shelf.

Program content1. The two-session general symposium, "Moving Frontiers of

Science," arranged by the Committee on AAAS Meet-ings.

2. The six sessions of the Conference on Scientific and Tech-nical Editorial Problems.

3. Details of the anniversary celebrations of the AAAS-Gordon Research Conferences, Botanical Society of Amer-ica, Freud et al.

4. Programs of the 18 AAAS sections (symposia and con-tributed papers).

5. Programs of the more than 80 participating societies.6. The Special Sessions: AAAS, Academy Conference, Con-

ference on Scientific Manpower, National GeographicSociety, Phi Beta Kappa, RESA, Sigma Xi.

7. Details of the Hotel Statler-center of the Meeting-andother hotels and session sites.

8. Titles of the latest foreign and domestic scientific filmsto be shown in the AAAS Science Theatre.

9. Exhibitors in the 1956 Annual Exposition of Science andIndustry and descriptions of their exhibits.

Directory content1. AAAS officers, staff, committees for 1956.

2. Complete roll of AAAS presidents and their fields.

3. The more than 265 affiliated organizations.

4. Historical sketch and organization of the Association;the 1955 revised Constitution and Bylaws.

5. Publications of the Association.

6. AAAS Awards and Grants-including all past winners.

7. Membership figures by sections.

8. Section committees (Council members) in detail.

9. Local committees.

10. Future Meetings of the AAAS through 1962.

11. New and current activities of the AAAS.

Advance RegistrationAdvance registration has these decided advantages: 1)You avoid delay at the Registration Center upon arrival; 2)You

receive the General Program-Directory in ample time to decide, unhurriedly, which events and sessions you particularly wish toattend; 3 )Your name is posted in the Visible Directory as the Meeting opens.

The following coupon may be used both by advance registrants and by those who wish onlythe advance copy of the General Program-Directory.

THIS IS YOUR COUPON FOR AN ADVANCE COPY OF THE GENERAL PROGRAM-DIRECTORY

la. E Enclosed is $3.00 for my advance Registration Fee which brings me the Program-Directory, Convention Badge, and allprivileges of the Meeting.

lb. Ol Enclosed is $2.00 for only the Program-Directory. (It is understood that, if I should attend the Meeting later, theBadge-which is necessary for all privileges of the Meeting-will be secured for $1.00 more.)

(Check one)

2. FULL NAME (Dr., Miss, etc.) ................................................................................(Please print or typewrite) (Last) (First) (Initial)

3. ACADEMIC, PROFESSIONAL, ORBUSINESS CONNECTION ...................................................................................

4. OFFICE OR HOME ADDRESS ...............................................................................(For receipt of Program-Directory)

5. YOUR FIELD OF INTEREST ...............................................................................

6. CONVENTION ADDRESS ..............(May be added later, after arrival)

Please mail this Coupon and your check or money order for $3.00 or $2.00 to theAMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE

1515 Massachusetts Avenue, N.W., Washington 5, D.C.140 SCIENCE, VOL. 124

APPLICATION FOR HOTEL RESERVATIONS123rd AAAS MEETINKG

New York City, December 26-31, 1956The list of hotels and their rates and the reservation coupon below are for your convenience in making your

hotel room reservation in New York. Please send your application, not to any hotel directly, but to the AAASHousing Bureau in New York and thereby avoid delay and confusion. (Members of the American AstronomicalSociety who wish reservations at uptown hotels should correspond directly with the Hayden Planetarium.) Theexperienced Housing Bureau will make assignments promptly; a confirmation will be sent you in two weeks or less.As in any city, single-bedded rooms may become scarce; double rooms for single occupancy cost more; fora lower rate, share a twin-bedded room with a colleague. Most hotels will place comfortable rollaway beds inrooms or suites at 2.50 or 3.00 per night. Mail your application now to secure your first choice of desired accommo-dations. All requests for reservations must give a definite date and estimated hour of arrival, and also probable dateof departure.

AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCERates for Rooms with Bath *

All hotels have sessions in their public rooms. For a list of headquarters of each participating society and section, pleasesee Science, July 20, or The Scientific Monthly for August.

Hotel Single Double Bed Twin Bed SuiteGovernor Clinton $7.00-11.00 $10.00-13.00 $11.00-17.00 $20.00-35.00Martinique 5.00- 9.00 8.00-14.00 8.00-14.00 16.00-38.00New Yorker 7.00-10.00 10.00-14.00 11.50-17.00 25.00 and upSheraton-McAlpin 6.75- 9.75 9.75-12.75 10.75-13.75 20.00 and upStatler 8.00-12.00 11.00-15.00 11.50-18.00 31.00-33.00

* Subject to 5% New York City tax on hotel rooms.

-.-.-.-.-.-.--THIS IS YOUR HOUSING RESERVATION COUPON.AAAS Housing Bureau90 East 42nd Street Date of Application .......................................New York 17, N. Y.Please reserve the following accommodations for the 123rd Meeting of the AAAS in New York City, Dec. 26-31, 1956:

TYPE OF ACCOMMODATION DESIRED

Single Room.Desired Rate.Maximum Rate............Double-Bedded Room .Desired Rate .......... Maximum Ratet............. Number inparty .

Twin-Bedded Room.Desired Rate .......... Maximum Rate.

Suite ...................... Desired Rate .......... Maximum Rate ............. Sharing this room will be:(Attach list if this space is insufficient. The name and address of each person, including yourself, must be listed.)

.................................................................-..............................................

First Choice Hotel................ SecondChoiceHotel..............HThird Choice Hotel..

DATE OF ARRIVAL ............... DEPARTURE DATE .(These must be indicated-add approximate hour, a.m. or p.m.)

NAME .........................................................................................................(Individual requesting reservation) (Please print or type)

ADDRESS ......................................................................................................(Street) (City and Zone) (State)

Mail this now to the Housing Bureau. Rooms will be assigned and confinned in order of receipt of reservation.20 JULY 1956 141

Lippich Type Polarimeter(Schmidt & Haensch)

A precision instrument for measuring the rotation of theplane of polarization of all optically active substances.Big advantage is its glass circle instead of a metal circle.The scale on glass, instead of on metal, in conjunctionwith a micrometer plate, permits direct reading withoutvernier, resulting in greater speed and precision ofreading. Glass circle is rigidly connected with theanaly zer and carries two scales, an angular scale indegrees arc and a scale in international sugar degrees.Sodium vapor lamp is an integral part of the instrumentand is alwaN-s in alignment and ready for use.

-iodel .4 sith receiving trough for tubes up to a length of 220 mm.

lIode I B ith receiving trouiglh foi tubes up to a lerigtli of 400 mni.

Bulletin SH-344 on request

FISH-SCHURMAN CORPORATION74 Portman Road New Rochelle, N. Y.

u, mA

?+ SCIENCE-1955195ON MICROCARDS

-K The response to the AMicrocard edition has *encouragec us to insake volumes 121 and 122 *

K of SCIENCE available in this form. *jc ~~~~~~~~~~*-K Seventy-seven 3" x 5" cards contain 2337 *

-K pages of SCIENCE for the year 1955. *Jc ~~~~~~~~~~*

-K The space saviing is considerable-25 sets *-K of MAicrocards take up approximately the *

same space as a single bound volume ofSCIENCE covering the same period. The *bother and expense of binding are conm-

-+ pletely eliminated. In spite of the increase *-K in format, the price remnains unclhanged: *

Jc ~~~~~~~~~~*-K Microcard edition of SCIENCE, 1953 $15.00 *

'of SCIENCE, 1954 $15.00 *

-K " " of SCIENCE, 1955 $15.00 *

-' Second half of 1955 only ........ $ 7.50 *

AAAS1515 Mass. Ave., NW *

Kt Washington 5, D.C. *

142SCIENCE, VOL. 124

KLETTELECTROPHORESIS

CUSTOM MADE

TOOL FOR THE ANALYSISOF COMPLEX COLLOID SYSTEMS, AND FORTHE CONTROL OF PRODUCTION OFPURIFIED PROTEINS, ENZYMES, HORMONES

KLETT MANUFACTURING CO.179 EAST 87TH STREETNEW YORK, N. Y.

I li I i M--M.

I.ok

142 SCIENCE, VOL. 124

CHROMATOGRAPHY

Before After

LKB 3348 Composite Column for ChromatographyBoth curves are from displacement chromatographic separationsof 10-mg Glucose, 10-mg Saccharose, and 30-mg Raffinose inwater, a 0.5%o Ephedrine solution being used as displacer. Equalamounts of adsorbent, Carboraffin Supra, were used. The only dif-erence between the two experiments-besides, of course, the verysuperior sharpness of the zones in the curve to the right-was thetype of column used: in the case shown to the left, one singlecolumn; in the case to the right, a 3-component column accordingto Hagdahl. Write for bulletin SC-79C.

Also of interest to workers in Electrophoresis and Chromatography:LKB 3340 Column Electrophoresis Appara-tus-for preparative work with both powderand density gradient columns.

LKB 3276 Paper Electrophoresis Equip-ment-for micro analysis, for example inclinics. Unrivalled resolving power.

LKB 3391 Grycksbo Chromatographic Fil-ter Paper Column-converts paper chroma-tography into a large-scale preparativemethod.I.K 3346 Fraction Collector-an accessoryapparatus for all fractionation by electro-phoresis and chromatography.

MANUFACTURER: LKB-PRODUKTER FABRIKSAKTIEBOLAG P. 0. Box 12035, Stockholm, Sweden

IN THE UNITED STATES AND CANADA, INQUIRIES FOR ALL LKB LABORA-TORY INSTRUMENTS SHOULD BE DIRECTED TO THE SOLE DISTRIBUTORS:

han SOrval Inc.0 Norwalk . ConnecticutP. 0. Box 230

RARE EARTHS AS CATALYSTS

An application which offers intriguing possibilities

a report by LINDSAY

EVER tried to burn a cube ofsugar? It can't be done, youknow-unless you use a cat-

alyst . in this case cigarette ashes.Dust the cube with ashes, apply amatch and presto-you have a juniorinferno.Of course, you're not vitally inter-

ested in burning cubes of sugar-aside from amazing your non-tech-nical friends. We mention this littleexperiment to focus attention on theuse of rare earths as catalysts.Cerium and cerium oxide are be-

ing used for this purpose in severalindustries. And it is highly probablethat among the other rare earths,you will find some that have impor-tant commercial possibilities in youroperations.

Interest in the rare earths as cat-alysts is gaining momentum. .-l-though we, at Lindsay, do not makecatalysts ourselves, we do supplyrare earth materials for this use.Here are some of the operationswhere rare earths may have a placein your industiy. Ammonia Synthesisand Oxidation, Combustion andOxidation, Dehydration, Dehydro-genation and Hydrogenation,Fischer-Tropsch Reaction, Haloge-nation, Metharol Synthesis, Poly-merization, Crude Oil Cracking,Paint Driers.

If any of these processes play apart in your plant operations, youmay find it richly rewarding to

investigate rare earths as catalysts.This is only one of the many, many

applications of these unique metals.Here at Lindsay, we have been refin-ing and developing rare earths forover 50 years and almost every daywe hear of new uses for them. Sci-entists in more and more industriesare turning to the rare earths in theirsearch for ways to improve theirproducts and processes.Take Lindsay's cerium oxide, for

example. It has revolutionized glasspolishing practices and is also usedin colorizing and decolorizing glass.

Lindsay's rare earth chloride (a

natural mixture of the chlorides ofcerium, lanthanum, neodymium andpraseodymium and some other rareearths) is used extensively in the tex-tile industry, the metal industry andin the manufacture of paint and ink.You'd be surprised at the diverse

uses of rare earths in today's indus-trial technology. It seems as if everytime you turn around, some re-searcher has found a new and prac-tical application for one or more ofthese amazing metals. That's whywe would like to suggest that youlook at the rare earths with an eyetoward their use as catalysts in youroperations.Some technical people have

tended to overlook the irare earths,believing them to be unavailable incommercial quantities. This is nottrue. Lindsay is engaged in largescale production of cerium, rareearth and thorium chemicals, andoffers them for prompt shipment inquantities from a gram to a carload.To aid you, the accumulated data

and the advice of Lindsay's tech-nical staff is at your service. Yourinquiry is invited.

PLEASE T ~ YURVIT (TITA T

ADDRESS INQUI RIES TO: LINDSAY 1HEMrICAL (OMPANY280 ANN STREET, WEST CHICAGO, ILL.