HumaStar 100 and 200 - Human In Afghanistan · HumaStar 100/200 • Low water consumption 2nd cleaning solution . Page 36 ... Mindray BS-200 Biosystems A25 Landwind C200i Open/closed

HumaStar 100

HumaStar 200

Key advantages

Competition

Product features

Rev. 08d 07.09.2015

Scope of supply

The slides provided in this section are concerned with availability, scope of supply and registration

of the products.

Scope of delivery

Page 5

• Wash Add

• Special Wash

Solution (NaOH)

• Cuvette Clean

(turbidimetry)

Included:

Instrument UPS

Accessory Kit

Not included:

Computer & Monitor

(necessary for operation)

Printer

Wash Solutions (necessary for operation)

Key advantages at a glance

Page 18

Reliable results and flexibility

Reagents and instruments from one supplier

Page 19

• Reliable results

• HUMAN methods pre-installed and validated

• Reagent cooling

Reliable results, less application work, less

supports, less cost

• Flexibility (Open analyzer)

• Substrates, enzymes, turbidimetry, electrolytes

Flexible to use other reagents

Reliable methods

Page 20

More testing than for any other open instrument

• Validation on 4 analyzers running for almost 1 year

• More than 140.000 tests

• Recovery (8 different controls)

• Precision (intra-assay and inter-assay 5 days, 3 levelsfor each)

• Limit of linearity

• Limit of detection

• Calibration stability

• Onboard stability

• Method comparison (internal and/or external AU400)

Pre-installed methods

Page 21

The laboratory has reliable results without doing

any application work by themselves.

Clinical Chemistry

Page 22

Last updated: 02.01.2015

ACID PHOSPHATASE HbA1c liquidirect

ALBUMIN liquicolor HDL CHOLESTEROL liquicolor

ALKALINE PHOSPHATASE liquicolor HOMOCYSTEINE liquiUV

ALKALINE PHOSPHATASE opt. liquicolor IRON liquicolor

alpha-AMYLASE liquicolor IRON TPTZ liquicolor

auto-BILIRUBIN-D liquicolor LDH SCE mod. liquiUV

auto-BILIRUBIN-T liquicolor LDL CHOLESTEROL liquicolor

auto-CREATININE liquicolor LIPASE liquicolor

CALCIUM liquicolor MAGNESIUM liquicolor

CHLORIDE liquicolor PANCREAS-AMYLASE liquicolor

CHOLESTEROL liquicolor PHOSPHORUS liquirapid

CK NAC liquiUV POTASSIUM liquiUV

CK-MB liquiUV SODIUM liquicolor

CREATININE (enzym) liquicolor TOTAL PROTEIN liquicolor

gamma-GT liquicolor TRIGLYCERIDES liquicolor

GLUCOSE liquicolor UREA liquiUV

GLUCOSE liquiUVmono URIC ACID liquicolor

GOT (ASAT) IFCC mod. liquiUV URIC ACID liquicolor plus

GPT (ALAT) IFCC mod. liquiUV

Immunoturbidimetry

Page 23

Last updated: 20.01.2015

anti-STEPTOLYSIN-O (ASO) CYSTATIN-C liquidirect

APOLIPOPROTEIN A1 (APO A1) IMMUNOGLOBULINS direct IgA

APOLIPOPROTEIN B (APO B) IMMUNOGLOBULINS direct IgG

COMPLEMENT C3 IMMUNOGLOBULINS direct IgM

COMPLEMENT C4 MICROALBUMIN

CRP-hs TRANSFERRIN

Intuitive user software

Page 26

Optimized for touch screen

Reliable results

and easy creation of new methods

Complete reaction curve for EVERY test

Page 27

Reliable results

Statistics for every sample - not only QC

Page 28

Page 29

0

20

40

60

80

50 100 150 200 250 300

Sam

ple

po

sit

ion

s

Throughput max. [t/h]

Long walk-away time

High number of sample positions assures long walk-away time

Efficient workflow

Ready for automation of modern laboratories

Page 30

• LIS with standard

Ethernet cable

• Full random-access,

free choice of

execution order

• Continuous loading

and STAT

• Primary tubes• Internal barcode

reader included

1 2

3 4

• Bi-directional LIS

• LIS standardized

according ASTM

Maximum flexibility

Wide choice of sample and reagent vials

Page 31

50 ml bottles

20 ml bottles

5 ml tubes 1 ml

cups

Reagents

5 ml tubes

Primary tubes

1 ml cups

3 ml tubes

Up to 16x100mm, 10 ml

7 ml tubes 3.5 ml

cups

Samples

Unique and recognizable design

Page 32

Page 33

0 t/h

100 t/h

200 t/h

Mindray BS-120 HumaStar 100 Biosystems A15 HumaStar 200

High typical throughput

HumaStar 100 has a constant throughput

for 1- and 2-shot methods

Double Shot Methods

Maximum - Single Shot

Typical Mix

Thro

ugh

pu

t

100 t/h 64 t/h

95 t/h 127 t/h

Page 34

Economic and efficient operation

Cuvette Wash Station

• Very low carry-over

• 8-step wash cycle

• 2nd cleaning solution

• Extra washing definable in method

• Automatic monitoring of cuvettes

Page 35

• 30.000 tests with 80 cuvettes

Low consumable cost

Price per test on instruments

without wash station can be

more than double the price on

HumaStar 100/200

• Low water consumption

2nd cleaning solution

Page 36

Available on HUMAN homepage:

SERVICE > FAQ Cost per test calculation

Reduce expenses

New clinical chemistry family (low to medium throughput)

HumaStar 100

(March 2013)

HumaStar 200

(Mai 2013)

HumaStar 300SR

(2017)

• Identical user software

• Identical hardware components

Page 37

Reduce expenses

• Identical user software

Reduced staff training

Reduced end-user training

Reduced support

• Identical hardware components

Reduced spare part stock

Reduced training for service engineers

Faster repair

Page 38

Modern and easy connection

USB

Ethernet cable

Windows 7 or XP *

(32- or 64-bit)

Page 39

No old RS-232 cable

* Windows 8 compatibility in evaluation

No result will be lost

Failure proof connection

Page 41

Easy maintenance

Monitoring of lifetime

Page 42

Pumps

Lamp Filters

Cuvettes

Easy maintenance

Access to lamp and pumps

Page 43

Pumps

Lamp

• High quality components

• High production depth

• Made in Europe

• Extensive testing

Reliable quality

Page 44

Competitive

advantages

0

20

40

60

80

50 100 150 200 250 300

Sam

ple

po

sit

ion

s

Throughput max. [t/h]

Page 46

BS-120

A15

Page 47

A25

Pentra C200

Cobas C111 BS-200 C200i

C200iplus

C100

C100plus

HumaStar 100 – Feature comparison 1

Human

HumaStar 100

Horiba

Pentra C200

Mindray

BS-120

Biosystems

A15

Roche

Cobas C111

Open/closed Open Closed Open Open Closed

Throughput max. 100 t/h const. 90 t/h const. 100 t/h 150 t/h 60 t/h

Reagent cooling Yes Yes Yes No Yes

Wash station Yes No No No No

Sample pos. 60 15 8 48 8

Reagent pos. 30 15x2 *1 28 20 14x2 *1

Barcode Internal Internal External ? Smp. & Rgt.

Primary tubes 16x100 mm Yes Yes 15x100 mm 16x100 mm

LIS ASTM Yes Yes Yes ASTM

Weight 51 kg 95 kg 75 kg 45 kg 35 kg

Water consumpt. < 1 l/h < 2.1 l/h 2.5 l/h 0.5 l/h < 2 l/day

ISE No Optional Optional No Optional

Cuvettes 80 washable 192 disposable 40 disposable 120 disposable 60 disposable

Page 48

*1 Nbr. of methods X Reag. per method


Human

HumaStar 100

Landwind

C100

Vital Scientific

Pro XS

Human

HumaStar 80

Open/closed Open Open Open Open

Throughput max. 100 t/h const. 150 t/h 75 t/h 80 t/h

Reagent cooling Yes Yes Optional No

Wash station Yes No No No

Sample pos. 60 40 25 54

Reagent pos. 30 40 30 20

Barcode Internal External External External

Primary tubes 16x100 mm Yes Yes No

LIS ASTM Yes LIS-2A Yes

Weight 51 kg 50 kg 67 kg 42 kg

Water consumpt. < 1 l/h 3.5 l/h (C100plus) 0.25 l/h

ISE None Optional No No

Cuvettes 80 washable 81 disposable 48 disposable 144 disp.

Comments

C100plus with Wash

station Batch, Flow-Cell

Page 49


Human

HumaStar 100

ISE Logotech

Miura One

Open/closed Open Open

Throughput max. 100 t/h const. 120 t/h

Reagent cooling Yes Yes

Wash station Yes Yes

Sample pos. 60 15

Reagent pos. 30 19

Barcode Internal Optional

Primary tubes 16x100 mm 13x85 mm

LIS ASTM Yes

Weight 51 kg 42 kg

Water consumpt. < 1 l/h < 2 l/h

ISE None Optional

Cuvettes 80 washable 80 washable

Comments

Page 50


HumaStar

200

Mindray

BS-200

Biosystems

A25

Landwind

C200i


Throughput max. 200 t/h 200 t/h 240 t/h 225 t/h

Reagent cooling Yes Yes Yes Yes

Wash station Yes (2 sol.) No No No

Sample pos. 60 40 72 60


Barcode Internal Internal ? Optional

Primary tubes 16x100 mm Yes 15x100 mm Yes

LIS ASTM Yes Yes HL7


Water consumpt. < 2 l/h 3.5 l/h (BS-200E) 1 l/h < 1,5 l/h

ISE No Optional No Optional

Cuvettes 80 washable 80 disposable 120 disposable 81 disposable

Comments

BS-200E with wash

station

C200iplus with wash

station

Page 51


HumaStar

200

Elitech

Flexor EL80

Elitech

Flexor EL150

Elitech

Flexor EL200



Reagent cooling Yes Optional Yes Yes

Wash station Yes (2 sol.) No Yes Yes

Sample pos. 60 25 25 80


Barcode Internal Optional external Internal Internal

Primary tubes 16x100 mm 13x75 mm 13x75 mm 13x75 mm

LIS ASTM LIS-2A LIS-2A LIS-2A


Water consumpt. < 2 l/h 250 ml/h 950 ml/h 500 ml/h

ISE No Optional Optional Optional

Cuvettes 80 washable 48 disposable 48 washable 48 washable

Comments Integraded PC Integrated PC

Page 52


HumaStar

200

Roche

Cobas C311

DiaSys

Respons 910

DiaSys

Respons 920

Open/closed Open Closed Closed Closed


Reagent cooling Yes Yes No Yes

Wash station Yes (2 sol.) Yes No Yes

Sample pos. 60 110 30 30

Reagent pos. 30 42 (casseettes) 30 (x2) 30 (x2)

Barcode Internal Internal Internal Internal

Primary tubes 16x100 mm 16x100 mm 16x100 mm ?

LIS ASTM Yes (RS 232) Yes Yes


Water consumpt. < 2 l/h 12 l/h < 1 l/h < 7.5 l/h

ISE No Yes No Yes

Cuvettes 80 washable Washable 105 disposable 45 washable

Comments

Page 53


HumaStar 200 FUJIFILM NX 500 Miura 200 Pictus 200

Open/closed Open Closed Open Open


Reagent cooling Yes Not necessary Yes No

Wash station Yes (2 sol.) Not necessary Yes (2 sol.) No

Sample pos. 60 1 49 48

Reagent pos. 30 ? 44 48

Barcode Internal Optional (extern) Optional (Smp&Rgt) Optional

Primary tubes 16x100 mm 16x100 mm 13x100 mm 13x100 mm

LIS ASTM Yes Yes ASTM

Weight 51 kg 25 kg ? 50 kg

Water consumpt. < 2 l/h None < 2 l/h <0.5 l/h

ISE No Yes Optional No

Cuvettes 80 washable Not necessary 80 washable 80 disposable

Comments POCT, dry chem. 1 arm

Page 54


HumaStar 200

Elitech

Selectra Pro M

Open/closed Open Open

Throughput max. 200 t/h 180 t/h

Reagent cooling Yes

Wash station Yes (2 sol.)

Sample pos. 60

Reagent pos. 30

Barcode Internal

Primary tubes 16x100 mm

LIS ASTM

Weight 51 kg

Water consumpt. < 2 l/h

ISE No

Cuvettes 80 washable

Comments

Page 55

vs.

Page 56

A15 HumaStar 100

HS100 vs. Biosystems A15

Page 57

Item Advantage Human Advantage Biosystems A15

Features • Wash Station (vs. disposable cuvettes)• Reagent refrigeration• UPS included• Sample barcode (especially interesting for LIS)• Crash detection of needle• Nbr. sample positions (60 vs. 48)• Nbr. reagent positions (30 vs. 20)• Show complete reaction curve

• 4 flexible racks for reagents and samples

Equivalent • No ISE• Primary tubes (16mm vs. 15mm)

• European origin• Open instrument

• 100 t/h constant vs. 150 t/h max (= ~95 t/h typical)

Methods/ Reagents

• Methods validated• One supplier for reagent and instrument

• Pre-filled in A15 reagent bottles (vs. MPR)


Page 58

Explanation

Advantage HumaStar The main advantages of HumaStar 100 are the wash station and reagent refrigeration. The wash station saves money and time. Money: A15 has consumable cost for disposable cuvettes. HumaStar can run 30.000 tests with only 80 cuvettes. Time: On A15 manual changing of cuvettes is necessary after a test was run. Reagent refrigeration leads to reliable results, longer on-board and calibration stability. On A15 the user either has to place the reagent in the refrigerator after every run, but he will loose time doing this. If he leaves the reagent on the instrument he will waste reagent when it gets warm and he has to throw it away - he is loosing money. A15 has flexible tray for reagents and samples. However the total number of samples and reagents that the user can place on the instrument is higher on HumaStar. UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost.

Equivalent Throughput: A15 has a maximum throughput which is 150 t/h, whereas HumaStar 100 can only reach a maximum of 100 t/h. But the throughput of HumaStar 100 is constant for 1- and 2-shot methods. In a typical mix A15 will only reach 95 t/h. => The throughput is equivalent on both instruments. Biosystems and Human both offer instruments, reagents, and validated methods “out of one hand”.

Advantage A15 Biosystems sells the reagent in bottles that can be placed directly on the instrument.

vs.

Page 59

Cobas C111 HumaStar 100/200

HS100/200 vs. Roche Cobas C111

Page 60

Item Advantage Human Advantage Roche Cobas C111

Features • Wash Station (vs. disposable cuvettes)• Big screen• A4 printing• Nbr. sample positions (60 vs. 8)• Up to 30 reagents/methods (vs. 14)

• Name and reputation of Roche• Small integrated PC, screen and printer• ISE (optional)

Equivalent • Reagent cooling• Primary tubes

• Sample barcode reader

Methods/ Reagents

• Pre-installed and validated methods

• Open instrument • Barcoded reagents in pre-filled bottles• 1-5 open channels (optional)

Throughput • 100 or 200 t/h (vs. 60 t/h)

HS100/200 vs. Roche Cobas C111

Page 61

Explanation

Advantage HumaStar The main difference is that Cobas C111 is a closed instrument. HumaStar 100/200 are open instruments. The user of HumaStar is not limited in the reagents and methods he wants to use on the instrument. Because Human has also pre-installed and validated methods, Cobas C111 does not have an advantage in that respect. There are three other massive advantages of HumaStar: -On HumaStar the user can place up to 60 samples, whereas only 8 samples can be placed on Cobas C111. This leads to a much a higher walk-away time on HumaStar. -The HumaStar has a wash station, which is much more cost and time efficient than disposable cuvettes on Cobas C111 (for explanation also see Biosystems A15). -HumaStar 100 and 200 are much faster than Cobas C111. The throughput of Cobas is only 60 t/h and much closer to HumaStar 80 than HumaStar 100 or 200.

Equivalent The possibility of automation of the laboratory workflow is equivalent on both instruments. HumaStar and Cobas C111 both can use primary tubes, they both have a built in sample barcode reader, both instruments have a standardized (ASTM) LIS protocol, and both instrument support continuous loading.

Advantage Cobas Roche reagents are ready to use in prefilled and barcode labeled bottles. Handling of reagent bottles is easier. The reputation of Roche is very good.

vs.

Page 62

Cobas C311 HumaStar 200

HS200 vs. Roche Cobas C311

Page 63

Item Advantage Human Advantage Roche Cobas C311

Features • Price of instrument and reagents • Low water consumption (<2 vs. 12 l/h) • Low energy consumption (<200 vs. 1500 VA) • Small footprint (width 69 vs. 134cm) • Low weight (51 vs. 270 kg) • LIS via RJ-45 (vs. RS-323) • No fixed water connection needed

• Name and reputation of Roche • ISE (optional) • Loading STAT and reagents without opening

instrument • Clot detection • More sample positions (110 vs. 60)

Equivalent • Reagent cooling • Primary tubes

• Sample barcode reader • Cuvette wash station

Methods/ Reagents


• Open instrument (50 methods programmable: Human or open channels)

• Barcoded reagents in pre-filled bottles • Master-Curve calibration on reagents • 42 reagent cassette positions

(vs. 30 bottles on HumaStar)

Throughput • 300 t/h (vs. 200 t/h) photometric • 180 t/h ISE

HS200 vs. Roche Cobas C311

Page 64

Explanation

Advantage HumaStar The main difference is that Cobas C311 is a closed instrument. HumaStar 100/200 are open instruments. No limitations regarding reagents and methods he wants to use. There are three main advantages of HumaStar: -Price of the instrument itself is much lower than C311. -Price of multi-purpose reagents on HumaStar 100/200 is lower than reagents for C311. -No need of a fixed water connection (deionized water)*. -Lower consumption of water. -Lower consumption of energy and takes up less room in the laboratory.

Equivalent Both instruments offers pre-installed and validated methods, which assure reliable results.

Advantage Cobas Roche reagents are ready to use in prefilled and barcode labeled bottles. Handling of reagent bottles and loading of STAT is easier. Throughput of C311 is higher and it can load more reagents (parameters) at the same time. The reputation of Roche is very good. Cobas C311 can benefit most of its advantages an a high throughput laboratory.

* Roche also uses water to reconstitute the reagent (high quality necessary)

vs.

Page 65

Pentra C200 HumaStar 100

HS100 vs. Horiba Pentra C200

•Pentra C200 has192 cuvettes in stock

•*1 Reagent cassete with R1 and R2

Page 66

Item Advantage Human Advantage Pentra C200

Features • Wash Station (vs. disposable cuvettes*)• Nbr. reagent positions (30 vs. 15x2*1)• Nbr. sample positions (60 vs. 15)• Less weight (51 vs. 95 kg)

• ISE (optional)• Integrated computer and screen• Cooled sample tray

Equivalent • Fixed cycle (const. throughput) 100 vs. 90 t/h• Reagent cooling

• Intuitive touch screen user software• Sample barcode included• Shock detection of needle

• Primary tubes

Methods/ Reagents


• Open instrument • Barcoded reagents in pre-filled bottles


Page 67

Explanation

Advantage HumaStar The main difference is that Pentra is a closed instrument. HumaStar 100/200 are open instruments. The user of HumaStar is not limited in the reagents and methods he wants to use on the instrument. Because Human has also pre-installed and validated methods, Pentra does not have an advantage in that respect. There are two other advantages of HumaStar: -On HumaStar the user can place up to 60 samples, whereas only 15 samples can be placed on Pentra . This leads to a much a higher walk-away time on HumaStar. -The HumaStar has a wash station, which is much more cost and time efficient than disposable cuvettes on Pentra (for explanation also see Biosystems A15).

Equivalent HumaStar 100 and Pentra both have a constant throughput which is approximately equivalent. Reagent cooling, primary tubes, sample barcode reader, and a shock detector are also present on both instruments.

Advantage Pentra Horiba offers reagents that are ready to use in prefilled and barcode labeled bottles. Handling of reagent bottles is easier. PC and monitor are integrated and do not need to be purchased separately.


Page 68

Customer claims… Possible reply!

“Pentra has an separate mixing unit. It should be faster.”

Pentra and HS100 both work with a fixed cycle. Thus having a fixed throughput for 1- and 2-shot reagents. HumaStar 100 has a 36 sec. cycle:

1 hour/36 sec. = 100 t/h Pentra C 200 has a 40 sec. cycle:

1 hour/40 sec. = 90 t/h => HS100 is even slightly faster than Pentra C200

“Because Pentra has disposable cuvettes, there is no carry over in the cuvettes. HumaStar 100/200 have washable cuvettes, which will lead to carry over.”

The washing procedure of HumaStar 100/200 is so sophisticated that carry over is comparable to disposable cuvettes. There are several measures to assure this: • 8- step washing of every single cuvette• Normal Systemic and a Special Wash solution are connected to the instrument (most

other instrument only have one type of wash solution).• A third wash solution „Cuvette Clean“ can be programmed in the methods settings if

necessary (e.g. turbidimetry).• The intensity of the washing can be increased from 1 (normal) to 4 (extended) in the

method settings if necessary.• The needle is washed internally and externally.• Incompatibilities can be defined in the method settings. This will prevent the

consecutive execution of parameters that could influence each other in one cuvette.=> In practice carry over is comparable on HumaStar and Pentra. HumaStar has the advantage of lower consumable cost (cuvettes).

vs.

Page 69

BS-120 HumaStar 100

HS100 vs. Mindray BS-120

Page 70

Item Advantage Human Advantage Mindray

Features • Wash Station• 60 sample positions (vs. 8)• Throughput 100 t/h const. (vs. 100 t/h max)• Internal sample barcode reader• Made in Europe• Intuitive touch screen user software

• Optional ISE

Equivalent • Reagent cooling• Nbr. reagent positions (30 vs. 28)

Methods/ Reagents

• Pre-installed and validated method• Reagents and instruments from one source

Service • Technical service available in most countries• Human offers local trainings

Comments


Page 71

Explanation

Advantage HumaStar

There are 5 massive advantages of HumaStar 100. -The wash station saves money and time. Money: BS-120 has consumable cost for disposable cuvettes. HumaStar can run 30.000 tests with only 80 cuvettes. Time: manual changing of cuvettes is necessary after a test has been run in a cuvette. -HumaStar 100 is much faster than BS-120. The max. throughput of BS-120 is 100 t/h, but the typical throughput will only be at approx. 60 t/h , because it is not constant for 1- and 2-shot methods. -On HumaStar the user can place up to 60 samples, whereas only 8 samples can be placed on BS-120. This leads to a much a higher walk-away time on HumaStar. -HumaStar is made in Europe. -HumaStar has pre-installed and validated methods. Users can be sure about the results. On BS-120 lots of time needs to be spend to reach a precision and performance of parameters as we have on HumaStar 100. Sometimes it will be impossible to reach the performance of HumaStar, because Human has the possibility to adapt the hardware and the software of the instrument to match the reagents. The user in the laboratory does not have this possibility. UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. The modern user software of HumaStar is easier to use and offers more features than Mindray.


Page 72

Explanation

Equivalent Reagent cooling. Number of reagent position is approximately equivalent.

Advantage BS-120

Optional ISE. However HumaStar can measure all electrolytes using chemical reagents. ISE modules often require high maintenance if the number of samples that are measured per day is not sufficient.

vs.

Page 73

Miura One HumaStar 100

HS100 vs. Miura One

Page 74

Item Advantage Human Advantage Miura One

Features • 60 sample positions (vs. 15)• 30 reagent positions (vs. 19)• Throughput 100 t/h constant

(vs. 150 t/h max., 76 typical)• Intuitive touch screen user software• UPS included• Primary tubes 16x100mm (vs. 13x85mm)

• Optional ISE• Optional internal reagent barcode reader

Equivalent • Wash Station• Reagent cooling• Made in Europe• Open instrument

• Needle crash detection• Internal sample barcode included

Methods/ Reagents

• Barcoded reagents

Service

Comments

vs.

Page 75

Kroma HumaStar 200

HS200 vs. Linear Kroma

Page 76

Item Advantage Human Advantage Miura One

Features • 60 sample positions (vs. 15)• 30 reagent positions (vs. 20)• Throughput 200 t/h (vs. 150)• Intuitive touch screen user software• UPS included• Primary tubes 16x100mm (vs. 13x100mm)

• Optional ISE• Internal reagent barcode reader

Equivalent • Wash Station• Reagent cooling• Made in Europe• Open instrument

• Needle crash detection• Internal sample barcode included

Methods/ Reagents

• Barcoded reagents

Service

Comments

vs.

Page 77

respons 910 HumaStar 200

HS200 vs. DiaSys respons 910

Page 78

Item Advantage Human Advantage respons 910

Features • Wash Station (vs. disposable cuvettes) • UPS included (end user value € 720) • Reagent refrigeration • Open instrument • Nbr. sample positions (60 vs. 30)

• Nbr. reagent positions (30 vs. 30x2) • STAT can be loaded without opening the cover

Equivalent • No ISE module • Barcoded primary tubes (16x100mm)

• European origin

Methods/ Reagents

• Methods validated • One supplier for reagent and instrument

• Pre-filled in respons reagent bottles (vs. MPR) • Internal reagent barcode reader

Throughput • Slightly higher (200 vs. 150 t/h)


Page 79

Explanation

Advantage HumaStar The main advantages of HumaStar 200 is the wash station. The wash station saves money and time. Money: respons 910 has consumable cost for disposable cuvettes. HumaStar can run 30.000 tests with only 80 cuvettes. Depending on your price per disposable cuvette of respons 910, the price per test can be twice as high as on HumaStar 200. Time: manual changing of cuvettes is necessary after a test has been run in a cuvette. UPS is included in the standard offer of HumaStar at no extra cost. HumaStar 200 is an open instruments. The user of HumaStar is not limited in the reagents and methods he wants to use on the instrument. Because Human has also pre-installed and validated methods, respons does not have an advantage in that respect. Reagent refrigeration leads to reliable results, longer on-board and calibration stability. On respons the user either has to place the reagent in the refrigerator after every run, but he will loose time doing this. If he leaves the reagent on the instrument he will waste reagent when it gets warm and he has to throw it away - he is loosing money. Throughput of HumaStar 200 is 50 t/h higher than respons 910. This is difference can make a difference in laboratories with a higher number of samples per day. User can also place 60 samples on HumaStar at the same time. On respons 910 user can only place half of that (30 samples), making HumaStar 200 faster and more suitable if the laboratory has a higher number of samples per day.


Page 80

Explanation

Equivalent DiaSys and Human both offer instruments, reagents, and validated methods “out of one hand”.

Advantage respons 910

DiaSys sells the reagent in bottles that can be placed directly on the instrument and are recognized by an internal barcode reader. On respons 910 user can place up to 30 different parameters, each of them can use up to two reagents. On HumaStar the user can place 30 different bottles. If a parameter uses two reagents it will occupy two positions, thus limiting the number of parameters loaded on the instrument. STAT samples can be loaded on respons 910 without opening the cover. On HumaStar 200 the user needs to press pause and wait for approx. 20 seconds before he can open the cover and place the STAT sample.

vs.

Page 81

respons 920 HumaStar 200


Page 82

Item Advantage Human Advantage respons 920

Features • Water consumption (2 vs. 7.5 l/h) • UPS included (end user value € 720) • Open instrument • Nbr. sample positions (60 vs. 30) • Weight (51 vs. 110 kg)

• Nbr. reagent positions (30 vs. 30x2) • Optional ISE module • Constant throughput of 200 t/h •

Equivalent • Cuvette wash station • Reagent refrigeration

• European origin

Methods/ Reagents

• Methods validated • One supplier for reagent and instrument

• Pre-filled in respons reagent bottles (vs. MPR) • Internal reagent barcode reader


Page 83

Explanation

Advantage HumaStar HumaStar 200 is an open instruments. The user of HumaStar is not limited in the reagents and methods he wants to use on the instrument. Users might be limited using respons 920, if they want to measure parameters that are not available from Diasys or reagents cannot be supplied on time. Because Human has also pre-installed and validated methods for its Multi Purpose Reagents, respons does not have an advantage in that respect. User can place 60 samples on HumaStar at the same time. On respons 920 user can only place half of that (30 samples), making HumaStar 200 more suitable if the laboratory has a high number of samples per day. HumaStar 200 is slightly smaller and its weight is only half the weight of respons 920. The water consumption of HumaStar 200 is much lower (< 2 l/h) than the water consumption of respons 920 (< 7.5 l/h)


Page 84

Explanation

Equivalent HumaStar 200 and respons 920 are very similar instruments. Human and DiaSys both supply instrument and validated reagents out of one hand. Thus the user can be sure, to get reliable results. Both instruments have a cuvette wash station and reagent cooling. Both instruments are of European origin, thus having a good reputation in the market.

Advantage respons 920

DiaSys sells the reagent in bottles that can be placed directly on the instrument and are recognized by an internal barcode reader. On respons 910 user can place up to 30 different parameters, each of them can use up to two reagents. On HumaStar the user can place 30 different bottles. If a parameter uses two reagents it will occupy two positions, thus limiting the number of parameters loaded on the instrument. Respons 920 has an optional ISE module for Na, K, Cl, Li.

vs.

Page 85

A25 HumaStar 200


Page 86

Item Advantage Human Advantage Biosystems A25

Features • Wash Station (vs. disposable cuvettes)• UPS included (end user value € 720)• Sample barcode included (value > € 500)

(especially interesting for LIS)• Shock detection of needle• Show complete reaction curve• Intuitive touch screen user software

• 3 independent sample racks

Equivalent • Nbr. sample positions (60 vs. 72), nbr. reagent positions (30 vs. 30)• No ISE

• Primary tubes (16mm vs. 15mm)• European origin

• Reagent refrigeration• Open instrument

Methods/ Reagents


• Pre-filled in A25 reagent bottles (vs. MPR)

Throughput • Slightly higher (200 vs. 240 t/h)


Page 87

Explanation

Advantage HumaStar The main advantages of HumaStar 200 is the wash station. The wash station saves money and time. Money: A25 has consumable cost for disposable cuvettes. HumaStar can run 30.000 tests with only 80 cuvettes. Time: manual changing of cuvettes is necessary after a test has been run in a cuvette. UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. The modern user software of HumaStar is easier to use and more intuitive (see screen shots on next slide).

Equivalent Biosystems and Human both offer instruments, reagents, and validated methods “out of one hand”. Number of samples and reagents are approximately equivalent. On HumaStar you can place primary tubes up to 16 mm, on A25 you can place primary tubes up to 15 mm.

Advantage A25 Biosystems sells the reagent in bottles that can be placed directly on the instrument. Throughput of A25 is 20% higher than HumaStar 200. However, in routine use this difference will not be noticed by the user.


Page 88

vs.

Page 89

BS-200 HumaStar 200


Page 90

Item Advantage Human Advantage Mindray

Features • Cuvette Wash Station• 60 sample positions (vs. 40)• UPS included• Made in Europe• Easy to use software• Less weight (51 vs. 116 kg)• Less water consumption (< 2 l/h vs. 3.5 l/h)

• Optional ISE• 40 reagent positions (vs. 30)

Equivalent • Throughput 200 t/h (even though Mindray has extra mixer)• Reagent cooling

Service • Technical service available in most countries• Human offers local trainings

Methods/ Reagents


Comments • BS-200E with Wash Station


Page 91

Explanation

Advantage HumaStar -If competing against BS-200 (not BS-200E): The wash station saves money and time. (see also A15 for explanation). If competing against BS-200E: The water consumption on HumaStar is lower. -On HumaStar the user can place up to 60 samples, whereas only 40 samples can be placed on BS-200. -HumaStar is made in Europe. -HumaStar has pre-installed and validated methods. (see also BS-120 for explanation) -UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. -The modern user software of HumaStar is easier to use and offers more features than Mindray. -The weight of HumaStar is only half the weight of BS-200.

Equivalent Throughput: The throughput on both instruments is approximately the same. Reagent cooling.

Advantage BS-200 Optional ISE. However HumaStar can measure all electrolytes using chemical reagents. ISE modules often require high maintenance if the number of samples that are measured per day is not sufficient. Number of reagent position is slightly higher. However multiple reagent trays can be handled (saved) by HumaStar.

vs.

Page 92

LW C200i HumaStar 200

HS200 vs. Landwind C200i

Page 93

Item Advantage Human Advantage Landwind C200i

Features • Cuvette wash station • Barcode scanner included • UPS included • Easy to use software • Made in Europe • Less weight (51 vs. 116 kg)

• Optional ISE • 60 reagent positions (vs. 30) • Slightly higher throughput (225 vs. 200 t/h)

Equivalent • Reagent cooling • 60 sample positions

Service • Human can offer technical service in most countries • Human offers local trainings

Methods/ Reagents

• Pre-installed and validated method • Reagents and instruments from one source

Comments • C200iplus with wash station (6 l/h)

HS200 vs. Landwind C200i

Page 94

Explanation

Advantage HumaStar -If competing against C200i (not C200iplus): The wash station saves money and time. (see also A15 for explanation). If competing against C200iplus: The water consumption on HumaStar is lower. -HumaStar is made in Europe. -HumaStar has pre-installed and validated methods. (see also BS-120 for explanation) -UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. -The modern user software of HumaStar is easier to use and offers more features than Landwind. Landwind software is very difficult to use. -The weight of HumaStar is only half the weight of C200i.

Equivalent Reagent cooling. Number of sample positions.

Advantage BS-200 The throughput is slightly higher on C200i. Optional ISE. However HumaStar can measure all electrolytes using chemical reagents. ISE modules often require high maintenance if the number of samples that are measured per day is not sufficient. Number of reagent position is higher. However multiple reagent trays can be handled (saved) by HumaStar.

vs.

Page 95

NX 500 HumaStar 200

HS200 vs. FUJIFILM NX 500

Page 96

Item Advantage Human Advantage NX 500

Features • Open instrument• A4 printout• 60 sample positions (vs. 1)• Lower price per test

• No calibration necessary• No water consumption• Compact and light weight• Optional plasma filter (whole blood)

Equivalent

Service

Methods/ Reagents

• More than 40 Human parameters pre-installed • Can be used with other reagents that areavailable on the market

• 28 + 3 parameters• FUJIFILM dri-chem reagent slides ONLY

Comments • Suited for central or hospital laboratories • Dry chemistry• POCT suited for physician's offices

HS200 vs. FUJIFILM NX 500

Page 97

Explanation

Advantage HumaStar -The HumaStar is an instrument suited for a central or hospital laboratory. It can load and run up to 60 samples at once. NX 500 can only run one sample at a time. NX 500 is a designated POCT instrument for physician’s offices or similar operation areas which run only very few samples. HumaStar also has an internal sample barcode reader, NX 500 only has an optional handheld scanner. -Price per test is much lower on HumaStar than on NX 500. NX 500 is optimized for easy operation, not for low cost or higher throughput. On NX 500 disposable consumables are used for plasma separation and pipetting (-> waste and cost). -HumaStar comes with more pre-installed parameters than NX 500. Some parameters, such as HbA1c are not available on NX 500. HumaStar is also an open system, you can use most clinical chemistry reagents that are available on the market. On NX500 you can only run the dry reagent slides which are provided by Fujifilm.

Equivalent

Advantage NX 500 -Easy operation: No on-site calibration necessary, no centrifugation of sample necessary. -Small footprint and low weight: Integrated computer and thermal printer.

vs.

Page 98

Pictus 200 HumaStar 200

HS200 vs. Pictus 200

Page 99

Item Advantage Human Advantage Pictus

Features • Wash Station (vs. disposable cuvettes)• UPS included (end user value € 720)• Reagent refrigeration• Primary tubes up to 16x100 mm (optional)• Sample barcode included (value > € 500)

(especially interesting for LIS)

• Nbr. reagent positions (30 vs. 48)

Equivalent • No ISE module• European origin

Methods/ Reagents


• Pre-filled reagent bottles (vs. MPR)

Throughput • Up to 200 t/h

HS200 vs. Diatron Pictus 200

Page 100

Explanation

Advantage HumaStar The main advantages of HumaStar 200 is the wash station. The wash station saves money and time. Money: Pictus 200 has consumable cost for disposable cuvettes. HumaStar can run 30.000 tests with only 80 cuvettes. Depending on your price per disposable cuvette of Pictus 200, the price per test can be twice as high as on HumaStar 200. Time: manual changing of cuvettes is necessary on Pictus 200 after a test has been run in a cuvette. UPS is included in the standard offer of HumaStar at no extra cost. Reagent refrigeration leads to reliable results, longer on-board and calibration stability. On Pictus 200 the user either has to place the reagent in the refrigerator after every run, but he will loose time doing this. If he leaves the reagent on the instrument he will waste reagent when it gets warm and he has to throw it away - he is loosing money.

Equivalent The throughput of both instruments is identical. Both instruments are of European origin. Both instruments offer validated applications for their reagents.

Advantage Pictus 200 -Users can load more reagents on board. (However these reagents must not stay on Pictus 200 for a long time, because it is not cooling the reagents.)

vs.

Page 101

Miura 200 (one arm) HumaStar 200

HS200 vs. Miura 200

Page 102

Item Advantage Human Advantage Miura 200

Features • Nbr. of sample positions (60 vs. 49)• More compact, less width on the desk (69 vs. 93cm)• Extractable reagent and samples trays• 4 types of reagent bottles (vs. 2)• 2 types of sample trays (4 types of tubes and cups)• Primary tubes up to 16x100 mm (optional)• Vitro-ceramic internally + externally coated probe (vs. no coating)• Internal + external needle wash• Continuous run, never stop, with rapid execution of urgent tests• Repetition of the calibration with recalculation of the results with the

new valid calibration• Multiple dyamic worklists (WL sheets)• LIS operating on dedicated WL sheets• Autodilution of the calibration including concentration of the sample

(dilution rate < 1)• Electronics easy accessible and separated from the hydraulics• Water consumption (mono-reagent 200 t/h) 1.5 l/h (vs. 3-4 l/h)• UPS included (end user value €720)• Sample barcode included (value>€500; especially interesting for LIS)

• Optional ISE module• Nbr. reagent positions (30

vs. 30/43)• Host query LIS• Optional internal reagent

barcode reader

HS200 vs. Miura 200

Page 103

Item Advantage Human Advantage Miura 200

Equivalent • Reagent cooling• Made in Europe• Open instrument

• Needle crash detection• Cuvette wash station

• Bi-directional LIS

Methods/ Reagents


• Pre-filled reagent bottles (vs. MPR)

Throughput • Up to 200 t/h (photometric)

HS200 vs. Logotech ISE Miura 200

Page 104

Explanation

Advantage HumaStar •UPS is included in the standard offer of HumaStar at no extra cost. •Sample barcode reader is included in the standard offer of HumaStar at no extra cost. •HumaStar 200 is more flexible in the type of reagent bottles you can use. You can use up to 4 different reagent containers (low dead volume = less reagent is wasted). •HumaStar 200 is more flexible in the type of sample tubes/cups you can use. On HumaStar 200 you have the choice between two different and extractable sample trays. You can also use 4 different sample tubes or cups and tubes up to 16mm diameter. •On HumaStar 200 you have internal AND external needle wash, minimizing shifted results due to needle carry-over. •HumaStar consumes less water than the Miura 200. •Imagine you have calibrated your instrument and you have finished running your patient tests. Then you find out that the calibration was not valid. On most instruments (including Miura 200) you would have to run all tests again. On HumaStar 200 you can just repeat the calibration and the recalculate all patient tests using the valid calibration. Thus your are saving a lot of reagent and time. •On HumaStar 200 electronic and hydraulic components are strictly separated. If there is a leakage in the hydraulics, the electronic components are protected from being destroyed by the water.

HS200 vs. Logotech ISE Miura 200

Page 105

Explanation

Equivalent •HumaStar 200 and Miura 200 are two very similar instruments. Some components areeven shared by both instruments. •Both instruments are of European origin.•Both instruments offer validated applications for their reagents.•Both instruments have a cuvette wash station and reagent refrigeration.•Photometric (without ISE) test throughput is 200 tests per hour on both instruments.

Advantage Miura 200 •Users can load more reagents on board. (However on HumaStar 200 it is possible towork with multiple extractable reagent trays.) •There is an optional ISE module for Na, K, Cl, Li available. (However Na, K, Cl areavailable for HS200 as liquid reagents.) •There are an optional internal reagent barcode reader and barcoded reagentsavailable. •Higher test throughput if ISE is included.

Product features

HumaStar 100 & 200

Product features

1. Design

2. Technology

• Main Features

• Hardware and Software

• Service and Maintenance

Page 109

Our Pioneers for a new Line of Instruments

HumaStar 100 & 200

Our Pioneers for a new Line of Instruments

Page 110

HumaStar 100 & 200

1. Design

2. Technology

• Main Features



Page 111

Product features

0 t/h

100 t/h

200 t/h

HumaStar 80 HumaStar 100 HumaStar 180 HumaStar 200

HumaStar 100 & 200

Throughput


Thro

ughput

Ma

xim

um

100 t/h

180 t/h

200 t/h

80 t/h

Page 112

0 t/h

100 t/h

200 t/h


HumaStar 100 & 200

Throughput Double Shot Reagents


100 t/h

Thro

ugh

pu

t D

ou

ble

Sh

ot

100 t/h

Page 113

0 t/h

100 t/h

200 t/h


HumaStar 100 & 200

Throughput

* independent of single- or double shot methods

Double Shot Reagents


Typical Mix

Thro

ugh

pu

t T

yp

ica

l

100 t/h

40 t/h

115 t/h 127 t/h

Page 114

HumaStar 100 & 200

Features • Open random-access

• Multi-step wash station

• Primary tubes (16x100 mm)

• Sample cups

• Reagent cooling

• 30 reagent and 60 sample positions

• Internal sample barcode reader

• Needle shock detector

• Bi-directional LIS (ASTM)

• Continuous loading

Page 115

HumaStar 100 & 200

1. Design

2. Technology

• Main Features



Page 116

Product features

HumaStar 100 & 200

Wash Station

• 8-step wash cycle

• 2nd cleaning solution

• Level sensors for all containers

• Difference HumaStar 100 vs. 200

• 6 vs. 8 cleaning needles

• Water consumption only 8 ml per test

Page 117

HumaStar 100 & 200

Samples

• Removable sample tray

• Primary tubes and cups

• 60 positions up to 12.5x100 mm

• Optional tray: 20+20 positions up to 16x100 mm

• Internal barcode reader included

Page 118

• HUMAN methods pre-installed and validated

• Substrates, enzymes, turbidimetry, electrolytes

• Open analyzer

• Removable reagent tray

• Reagent cooling

• 30 positions (one used for diluent)

• 4 different reagent vials

HumaStar 100 & 200

Reagents

Page 119

HumaStar 100 & 200

1. Design

2. Technology

• Main Features



Page 121

Product features

HumaStar 100 & 200

User Interface and Features

Page 122

HumaStar 100 & 200


• Easy to use

• Touch screen

Page 123

HumaStar 100 & 200


• Easy to use

• Touch screen

• 5 main tabs

• One software -

Complete analyzer line

Page 124

HumaStar 100 & 200

Extensive Information

• Reaction charts

Page 125

HumaStar 100 & 200


• Reaction charts

• Quality control charts

Page 126

HumaStar 100 & 200


• Reaction charts

• Quality control charts

• Method statistics

Page 127

HumaStar 100 & 200

LIS

Ext. Computer and LIS

HumaStar

• PC via USB

• ASTM standard

• Bi-Directional

Page 128

HumaStar 100 & 200

1. Design

2. Technology

• Main Features


• Usability and Safety


Page 129

Product features

HumaStar 100 & 200

Minimum Maintenance

• Monitoring of life time

• Pumps

Page 130

HumaStar 100 & 200

Minimum Maintenance


• Pumps

• Filters

• Lamp

Page 131

HumaStar 100 & 200

Minimum Maintenance


• Pumps

• Filters

• Lamp

• Cuvettes

Page 132

• Quality

• High quality components

• High production depth

• Made in Europe

• Extensive testing

• Easy access

HumaStar 100 & 200

Minimum Service

Page 133

HumaStar 100 & 200

Minimum Service

• Quality

• Easy access

• Lamp

Page 134

HumaStar 100 & 200

Minimum Service

• Quality

• Easy access

• Lamp

• Peristaltic pumps

Page 135

HumaStar 100 & 200

Minimum Service

• Quality

• Easy access

• Lamp


• Remove top cover

Page 136

HumaStar 100 & 200

Minimum Service

• Quality

• Easy access

• Lamp


• Remove top cover

• Remove complete cover

Page 137

HumaStar 100 & 200

Size and Weight

51 kg

76 cm

69 cm

52 c

m

169 cm

Page 138

The end

“Get in the race and ask

for more information

about HumaStar 100

and 200.“

Page 141

Documents

HumaStar 100 and 200 - Human In Afghanistan · HumaStar 100/200 • Low water consumption 2nd cleaning solution . Page 36 ... Mindray BS-200 Biosystems A25 Landwind C200i Open/closed