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HUMAN AGINDSYSTEM DIAGRAM
(HASD)RCAT – Research center
of advanced technologies
Imminst Conference-2010, 10-th October, 2010by Valerija Pride
http://www.sciencevsaging.org/
HistorySeptember 2008Medvedev D.
The goal
A systemic organization of accumulated knowledge
and determination of future directions to solve the problem of aging of
human organismФото: Corbis
A project of Russian Transhumanist Movement started in 2010Some of the projects it operates:
CAD software NanoInventor Human Aging System Diagram Telepresence robot “Teleput” “Path of upgrade” training center Industry report of the fight against aging field
RCAT – Research center of advanced technologies
Place
Gerontologists have their
puzzles too
Multidiscipline project HASD – is a multidiscipline project between gerontology and cognitive science
1. Геронтологи, молекулярные биологии иные специалисты
обладают знанием предмета
2. Методологи-когнитивщики обладают знанием о знании
как получить знания от специалистов как их оценить как организовать полученные знания
как сделать их доступными определить требуемую меру полноты
как получить новые знания и возможности
Specific
Three pillars in the basicof our results
1.
scie
nti
fic
meth
od
olo
gy
2.
meth
od
olo
gy o
f w
ork
ing
3.
vis
ual
meth
ods
Methodology
WHAT ?
1. Our diagram describes human aging. We ignore the aging of other species. At the same time we may extrapolate some data from laboratory animals to humans.
Comment: This is quite common in hot areas of science of human biology.
Scientific methodology
What ?2. We think it’s necessary to extract the cause-and-effect relationships between the aging processes (properly described), not all processes that happen in the organism. At the same time, constant processes, such as “digestion” are not included, but more specific processes, such as “decrease of gastric juice”, can be (if it’s related to aging).
Scientific HASD methodology
HOW ?3. So how do we describe aging? In the Human Aging System Diagram we have concentrated on describing the human aging processes. So the basic units of information are different processes connected to blocks.
So, HASD is not a diagram of metabolic pathways.
Scientific HASD methodology
HOW ?4. We describe aging starting at the top (natural primary causes) through cell disruption, decrease of function in tissues and organs and ending in pathologies and organism death (at the bottom). The entire process is one-directional (from top to bottom).
↓
Scientific HASD methodology
The initial aging-related HASD
HOW ?5. No feedback loops
Scientific methodology
Scientific methodology
6. The diagram should give sufficiently detailed elaboration of processes of ageing. The degree of elaboration is defined by internal logic of processes and the need to display sufficient details of aging process.
Additionally The diagram qualitatively describes, but
does not model the aging processes. In particular, the scheme is not equivalent to a computer model. Entering of numerical values into the diagram is supposed to happen at later stages of development of the project.
Other diagrams can be connected with HASD during the project.
Scientific methodology
Working methodology
Collecting knowledge (work with gerontologists and others)
expert interview using our methodology distributed work
Computer’s instruments CmapTools Get Satisfaction
Analysis TRIZ and other tools
HASD work methodology
CMAP Tools
GetSatisfaction
GetSatisfaction
Cognitive convenience and more
Visualization
Источник: www.math.yorku.ca/SCS/Gallery/
Visualization
“Report on the collapse of a bridge over the Rhone” in 1840 by visual engineer C. J. Minard:
Can you see why didthe bridge collapse?
Источник: VisualComplexity.com
Scientific evidence of effectiveness of modern supplements (for heart disease)
Visualization
HASD
HASD, var. № 50
meet
Top level diagram HASDFi
rst v
ersi
on
Second version
Our first experience in visualization
The authors1. The concept author & first director of the project:
Danila Medvedev, PhD, Research center for advanced technologies (RCAT), Moscow, Russia;
2. Artyuhov I.V., Institute of the Biology of Aging , Moscow, Russia;
3. Kaurov B.A., The Russian Roszdrav Research and Clinical Gerontological Center, Moscow, Russia;
4. Krementsova A.B., PhD, Institute of Biochemical Physics named after N.M. Emmanuel, Moscow, Russia;
5. Moskalev A.A., PhD, The Komi Institute of Biology of the Ural Region Research Center of the RF Academy of Sciences, Syktyvkar, The Komi Republic, Russia;
6. Mamayev V.B., PhD, Institute of Biochemical Physics named after N.M. Emmanuel, Moscow, Russia;
And…
6. Pasyukova E.H., PhD, Institute of Molecular Genetics, Moscow, Russia;
7. Sarvilina I.V., PhD, ООО «Medical Center «Novomeditcina», Rostov-on-Don, Russia;
8. Pride V., Research center for advanced technologies (RCAT), Moscow, Russia;
9. Yezhov M.D., Research center for advanced technologies (RCAT), Moscow, Russia;
10. Ilyin P.A., Research center for advanced technologies (RCAT), Moscow, Russia;
11. Maybe You ????;
Thank you for your attention!
Research center of advanced technologiesHuman Aging System [email protected]
Our Sponsor: Group «Rostok»www.grostock.ru , A. ChikunovRussian Transhumanism Movementwww.transhumanism-russia.ru
Valerija [email protected] +7 962 947-50-79
