HPLC method development Chromatography productsfiles.pharmtech.com/alfresco_images/pharma/2014/08/...instrument holds as many as 12 microplates and has ... Plate cap mat and heating

Information location service

eLabNotebook is an applications-based service onBeckman Coulter’s web site that enables users tolocate information about applications for the com-pany’s life-science research products. Materials such asapplication bulletins, troubleshooting tips, andproduct specifications for specific applications aregrouped together. Beckman Coulter, Inc., Fullerton,CA.

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176 LCGC NORTH AMERICA VOLUME 20 NUMBER 2 FEBRUARY 2002 www.chromatographyonline.com

HPLC method developmentThe Cogent Mini-Scout HPLC methoddevelopment kit from MicroSolvTechnologyCorporationincludes five 75 mm� 4.6 mm HPLCcolumns, and ahand-tightenedcolumn coupler thatdoes not introduceextracolumnvolume. Usersreportedly cancustomize the kit by

choosing from 17 selectivities. MicroSolv TechnologyCorp., Long Branch, NJ.

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Fluorescence detector

The model 2475 Multi-1 fluorescence detector fromWaters is designed for quantitating low concen-trations of target compounds that are either naturallyfluorescent or derivatized with a fluorescent tag. Thedetector uses on-board wavelength accuracy verifi-cation based on comprehensive qualification methodsthat check excitation and emission gradients. WatersCorp., Milford, MA.

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Chromatography productsUpchurch Scientific’s2002 catalogdescribes more than100 products foranalytical and diag-nostic laboratoryapplications,including micro- andnanoscale functions.The publicationincludes photo-graphs and charts,application notes,technical infor-mation, andmaterial–solvent

compatibility. Upchurch Scientific, Oak Harbor, WA.

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LC–MS capillary columns

Vydac LC–MS capillary columns from Grace Vydac areavailable with 75-, 150-, 300-, and 500-�m innerdiameters and in lengths from 50 to 250 mm. Thecolumns are packed with the company’s 300-Å poresilica and are available with polymeric C4, C8, andC18; diphenyl; and monomeric C18 reversed-phaseadsorbents. Grace Vydac, Hesperia, CA.

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Flow-cell cleaner

Wyatt’s COMET flow-cell cleaning device can beintegrated with a flow-cell manifold of the company’sminiDawn and miniDawn Tristar light-scatteringinstruments. The device applies a radio frequencyultrasonic field that prevents cavitation bubbles fromforming. The company reports that the deviceremoves particles that have adhered to cell walls and,with periodic activation, can prevent adhesion of newparticles. Wyatt Technology, Santa Barbara, CA.

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Proteomics workstation

Thermo Finnigan’s ProteomeX system is a fully inte-grated, multidimensional capillary LC–MS workstationdesigned for proteomics analyses such as high-throughput protein and peptide identification. Thesystem includes the company’s LCQ Deca SP ion-trapmass spectrometer, Surveyor HPLC system, andTurboSequest and BioWorks postacquisition protein-analysis software. Thermo Finnigan, San Jose, CA.

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Laboratory glasswareA catalog fromKimble/Kontes listsproducts forchemistry and life-science laboratories.Featured productsinclude a range ofreusable anddisposableglassware. Thecatalog includes atechnical section.Kimble/Kontes,Vineland, NJ.

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Liquid-handling instrument

Gilson’s Constellation 1200 high-throughput liquid-handling instrument is designed for genomics,proteomics, and drug discovery applications. Theinstrument holds as many as 12 microplates and has12 dispensing channels for noncontact dispensing ofvolumes as small as 50 nL. Gilson, Inc., Middleton, WI.

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Chromatography software

ChromManager chromatography software fromAdvanced Chemistry Development features an appli-cations database with more than 2900 separations.Users can store chromatograms in a database that canbe searched by structure, substructure, chromato-graphic parameter, and user-defined data. AdvancedChemistry Development, Toronto, Ontario, Canada.

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Binary-gradient controller

Jones Chromatography’s GradMaster binary-gradientcontroller is designed for flash chromatography andlow-pressure LC purification in synthetic andbiological chemistry applications. The controller canbe used to mix solvents and form linear, step, andcombination gradients. Jones Chromatography, Inc.,Lakewood, CO.

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Chromatography productsRestek’s 2002 cat-alog describes thecompany’s chro-matographyproducts includinganalytical referencematerials, HPLC andGC columns andaccessories, gas-purification com-ponents, andsample preparationproducts. The 700-page publicationcontains more than500 chromatograms

as well as technical information of interest to chro-matographers. Restek Corp., Bellefonte, PA.

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www.chromatographyonline.com FEBRUARY 2002 LCGC NORTH AMERICA VOLUME 20 NUMBER 2 181

Plate cap mat and heating block

MicroLiter Analytical Supplies’ plate cap mat andanodized aluminum heating block are designed foruse with the company’s plate-sampling system. Theaccessories enable users to maintain a 96-well plateformat while moving glass inserts from the carrierplate to the heating plate. The cap mats are availablewith insert sample capacities ranging from 200 �L to2.2 mL. MicroLiter Analytical Supplies, Suwanee, GA.

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Capillary column

SGE’s SolGel-Wax capillary column is designed for theanalysis of essential oils, food additives, industrialchemicals, aromatic hydrocarbons, and fatty acidmethyl esters. The column comprises a bonded poly-ethylene glycol stationary phase encapsulated insynthetic glass that is bonded to the surface of afused-silica capillary. SGE, Inc., Austin, TX.

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Centrifugal chromatography system

Analtech’s Cyclo-graph II chroma-tography systemuses centrifugalforce to producethin-layer radialseparations. Thecentrifugal forceaccelerates capillaryaction of the sol-vent through anadsorbent layer andreduces fraction col-lection times to asshort as 20 min. Thesystem includes a

solvent pump, tubing, a UV lamp, and reusable drop-in rotors. Analtech Inc., Newark, DE.

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Method development software

LC Resources’ DryLabMDW method development wiz-ard is a component of the company’s DryLab 2000chromatography software. The wizard guides usersthrough a strategy for developing reversed-phaseHPLC methods. The wizard reportedly collects basicinformation about method requirements and priori-ties, and proposes conditions for calibration runs. LCResources Inc., Walnut Creek, CA.

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Capillary GC columnsA data sheet fromAlltech describes the company’s AT-AquaWax andAT-AquaWax-DAcapillary GC columnsfor splitless andaqueous injections.The publicationdiscusses the col-umns’ suitability foranalyses of flavorand odor compo-nents of alcoholicbeverages; underiv-atized free fatty

acids; and acidic organic compounds such as phenols.Alltech Associates, Inc., Deerfield, IL.

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Chromatography products and accessories

Optimize Technol-ogies’ 2002 catalogdescribes the com-pany’s componentsfor HPLC, LC–MS,and sample trap-ping and cleanup.The publicationincludes informationabout thecompany’s trapcartridges, low-

volume traps, and LC and LC–MS columns. Otherproducts listed include HPLC check valves, guardcolumns, and quick-connect hardware. OptimizeTechnologies, Oregon City, OR.

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GC accessory kit

Supelco’s CAP kit for gas chromatography includesone of the company’s capillary GC columns and aselection of high-performance accessories such asinlet liners, septa, ferrules, inlet seals, O-ring seals,and column nuts. The kit reportedly reduces instru-ment downtime. Supelco, Inc., Bellefonte, PA.

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Molecular proteomicsA data sheet fromESA describes anapproach for under-standing proteomicsat the cell and tissue levels. Thepublication dis-cusses the interfacebetween proteomicsand chemicalbiology and explains how toaccess informationcontained withinthe small molecularinventory of a cell.

ESA Inc., Chelmsford, MA.

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Desorption instrumentCDS Analytical’swafer desorber isdesigned for con-densable andcontaminationsampling of semi-conductor waferswith diameters aslarge as 300 mm.The device vola-tilizes contaminantsfrom the surface ofwafers and directsthe contaminants toan analytical instru-ment such as a

GC–MS system. CDS Analytical, Inc., Oxford, PA.

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Dual-plate autosampler

Alcott Chromatography’s 718ALD dual-plate auto-sampler is designed to deliver maximum throughputand efficient on-line sample preparation. Theautosampler includes a sampling-port flush featurethat reportedly can reduce sample-carryover levels tobelow LC–MS detection limits. Users can add a platechanger to increase dual microplate and vial traycapacity for high-throughput applications. AlcottChromatography, Norcross, GA.

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Capillary tubingLTSP light-guidingcapillary tubingfrom PolymicroTechnologies isdesigned forapplicationsincludingfluorescencedetection andcoaxial light-activatedchemistries. Thesilica capillarytubing is clad with a layer of fluorine-doped synthetic

fused silica and coated with polyimide to providefiber-optic light transmission properties similar tothose found in step-index multimode optical fibers.Polymicro Technologies, LLC, Phoenix, AZ.

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Nutraceutical analysisA brochure fromWaters describes thecompany’s instru-ments, columns, andsample preparationproducts for nutra-ceutical analyses.The brochure dis-cusses the com-pany’s HPLC, LC–MS,and autopurificationsystems, software,and detectortechnologies foranalyses of samplessuch as extracts,

contaminants, and adulterants. Waters Corp., Milford,MA.

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Chromatography suppliesA catalog fromDelta TechnicalProducts lists thecompany’s chroma-tography productsand supplies. Thecompany hasdesigned the cat-alog to be easilynavigable, withinstrument-specificproduct indexing.Products includeautosampler vials,HPLC–GC main-tenance supplies,

and fittings. Delta Technical Products, Des Plaines, IL.

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LC–MS system

Amersham Biosciences’ Ettan LC–MS system isdesigned for protein analysis. The integrated systemcombines the company’s electrospray-ionization time-of-flight MS system with a microbore or capillary LCsystem. The system uses Unicorn control software,which includes a feature that enables peptide-massfingerprinting and protein identification. AmershamBiosciences, Piscataway, NJ.

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Ion-exchange LC columns

Tosoh Biosep’s TSK–Gel BioAssist ion-exchange LCcolumns are designed for separating monoclonalantibodies and other proteins, enzymes, and plas-mids. The columns are available in 5 cm � 4.6 mmPEEK housings and can be used with HPLC or fast-protein LC systems. Tosoh Biosep LLC, Montgomery-ville, PA.

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SPE columnsIsolute HCX-Q SPEcolumns from Inter-national SorbentTechnology aredesigned for theextraction ofquaternary amineand other basicdrugs frombiological fluids. The columns areavailable in 96-well-plate and 1-mL single-columnformats, withsorbent bed masses

of 25, 50, and 100 mg. International SorbentTechnology, Hengoed, United Kingdom.

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HPLC column

The Prevail C18 HPLC column from Alltech is availablein a range of phases and hardware formats.According to the company, the column’s high carbonload allows it to retain nonpolar, hydrophobic mol-ecules in the presence of 100% organic mobilephases, and the bonding process stabilizes the columnin highly aqueous mobile phases. Alltech Associates,Inc., Deerfield, IL.

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Chromatography productsMacherey-Nagel’scatalog describesthe company’sproducts andaccessories for HPLC,GC, SPE, and TLC.The 392-pagepublication discussesproducts such asHPLC columns andcartridges, low-bleed and fused-silica GC columns,and derivatizationreagents. The cat-alog emphasizes

products designed for environmental, food, biochem-ical, clinical, and enantiomer analysis. Macherey-Nagel, Easton, PA.

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HPLC systemsA DVD–CD-ROMdisk set fromAgilentTechnologiespresents anoverview of thecompany’s 1100series modules andsystems, which aredesigned for arange of HPLC

applications. The 10-min video includes 3-Danimations that explain the systems’ modular designsand other features and includes interviews featuringcompany employees who explain the systems’ usesand applications. Agilent Technologies Inc., Palo Alto,CA.

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Valve self-washing systemLeap Technologies’valve self-washingaccessory isdesigned for usewith the company’sHTS and HTC PALautosamplers. Theaccessory enablesusers to performsyringe and valvecleaning stepssimultaneously. Thedevice reportedlyhelps increasethroughput, extendsyringe life, and

reduce carryover. Leap Technologies, Carrboro, NC.

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Column–compound indexHamilton’s 12-pagecolumn–compoundindex lists com-pounds that havebeen separatedusing the company’sHPLC columns. Morethan 1300 com-pounds are listedalphabetically. Thebrochure includes a form for orderingapplication chro-matograms.Hamilton Co., Reno,NV.

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Chemical sensor systemThe ChemSensor4440 from Gerstel is an MS-basedchemical sensorsystem designed forquality-controlapplications such asfood, flavor, andpolymer analyses.The instrumentincludes an auto-mated headspacesampling systemand multivariatechemometricssoftware. Gerstel,

Inc., Baltimore, MD.

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HPLC filters

Whatman’s Mini-Uniprep HPLC filters are designed tobe used in place of syringe-coupled filters and auto-sampler vials. The sample preparation filters includean ergonomically engineered compressor that canaccommodate as many as six of the filters simul-taneously. Applications include protein precipitationand solubility studies. Whatman, Inc., Clifton, NJ.

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Autosampler data sheetA data sheet fromJasco describes thecompany’s modelAS-1555 and AS-1555-10 sampleinjection systems,which are designedfor use either asstand-alone mod-ules or as part of anintegrated HPLCsystem. The publi-cation discussesfeatures of theautosamplers suchas nonadsorbent

tubing and random sample access. Jasco, Easton, MD.

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HPLC radioactivity detectorA brochure fromraytest describes theRamona Star HPLCradioactivity flowmonitor designedfor applicationsincluding metab-olism studies,pharmacokinetics,and radiochemicalpurity determi-nation. The bro-chure includestechnical data andgraphs illustratingdetector efficiency

based on particle size. raytest, Wilmington, NC.

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Gas and equipment catalogA catalog from ScottSpecialty Gases listspure and mixedgases for chroma-tography and otherlaboratory appli-cations. The publi-cation also lists gas-handling equipmentavailable from thecompany such asflowmeters andmanifolds.According to thecatalog, gases areavailable in high-

pressure cylinders or in the company’s nonreturnablecylinders. Scott Specialty Gases, Plumsteadville, PA.

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GC systemThermo Finnigan’sTrace gas chromato-graph includes acold on-columninjector for theanalysis of ther-mally labile com-pounds withoutsample discrim-ination. The instru-ment’s modularinjection systems,and interchangeableionization detectorsare designed toallow users to per-

form a range of GC applications. Thermo Finnigan,San Jose, CA.

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Hydrogen generatorQuadrex’s Peakhydrogen generatoris designed for GCflame ionization,carrier gas, andother industrialapplications. Thegenerator uses ion-exchange mem-branes to producehydrogen with99.9999% purity.According to thecompany, thegenerator’s max-imum output flow

rate ranges from 200 cc/min to 600 cc/min, dependingon the model. Quadrex Corp., Woodbridge, CT.

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Centrifugal partitionchromatography system

A brochure fromRichard Scientificdescribes the com-pany’s KromatonFCPC centrifugalpartition chroma-tography system.The publicationexplains how thesystem can be usedfor fractionation,purification,isolation, andextraction ofnatural and syn-thetic products. The

brochure includes an explanation of the principle ofcentrifugal partition chromatography. RichardScientific Inc., Novato, CA.

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Field-flow fractionation system

The Eclipse asymmetric field-flow fractionation systemfrom Wyatt Technology integrates with the com-pany’s multiangle light-scattering instruments toprovide absolute size and molar mass distributions.The company reports that the system allows sepa-rations of particles and molecules in the submicro-meter size range. Applications include molecularbiology and environmental analyses. WyattTechnology Corp., Santa Barbara, CA.

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HPLC columns

Acclaim 120 reversed-phase HPLC columns fromDionex come in two particle sizes, two stationary-phase chemistries, and 28 configurations. Thebonded-silica columns, which are designed for low-bleed LC–MS applications, are available in C18 and C8phases. Dionex Corp., Sunnyvale, CA.

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Test samplesA brochure fromAbsolute Standardsdescribes thecompany’sAbsoluteGrade PTsamples for labo-ratory proficiencytesting of com-pounds in matricessuch as water,wastewater, soil,and food. Thebrochure reportsthat the samplesmeet criteria forNational Institute of

Standards and Technology–National VoluntaryLaboratory Accreditation Program Code 200390-0,National Environmental Laboratory AccreditationCouncil, and protocols for all states. AbsoluteStandards, Inc., Hamden, CT.

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Chiral application guideThe 88-page ChiralHPLC ApplicationGuide III from Regiscontains more than500 chiral sepa-rations performedwith the company’sPirkle chiral station-ary phases. Theguide is indexed bycompound nameand by column type for cross-referencing. RegisTechnologies, Inc.,Morton Grove, IL.

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Optical microscopeThe PicoViewoptical microscopefrom New Objectiveis designed for usewith the company’sPicoSPM molecularimaging system. Thedevice has a user-configurable,modular mountingplatform and a tip-mounting systemthat attaches to ahigh-precision stagefor either junction-style or tip-style

high-voltage contact. Applications include high-performance proteomics and biomolecule analysis.New Objective, Inc., Woburn, MA.

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Liquid syringesHamilton hasdesigned threesyringes to be usedwith CTC/LEAPTechnologiesautosamplers. Thesyringes include theMicroliter syringe,the ModifiedMicroliter syringe,and the Gastightsyringe, which has aPTFE-tippedplunger. HamiltonCo., Reno, NV.

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Vacuum controllerA vacuum controllerfrom Orochem Tech-nologies includes a timer for uniform,repeatable vacuumapplication. A startbutton allows usersto control vacuumintensity electron-ically during sampleaddition, elution,and washing. Thecompany reportsthat the instru-ment’s universalpower input design

enables process control to be transferred between110 and 220 V. Orochem Technologies, Oak Brook, IL.

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Sample preparation module

Metrohm-Peak’s model 793 IC sample preparationmodule eliminates difficult sample matrices in IC byintegrating the sample preparation step into IC sys-tems. Matrix elimination reportedly occurs in-line andcartridge regeneration and rinsing occur simulta-neously off-line. Metrohm-Peak, Inc., Houston, TX.

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Analytical data managementeRecordManager2001 release 1 fromThermo LabSystemsis an Oracle-baseddata-managementand archiving soft-ware program thatis designed forstoring spectral andchromatographic

data from multiple data formats. The program issupported on Microsoft Windows 2000, NT4, and 98and is compliant with 21 CFR Part 11. ThermoLabSystems, Beverly, MA.

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GC system

The GC-2010 system from Shimadzu ScientificInstruments is designed for fast-GC applications suchas food, petrochemical, and pharmaceutical analyses.The system includes a self-diagnostic function, a fast-heating oven, and as many as four high-sensitivitydetectors. Shimadzu Scientific Instruments, Inc.,Columbia, MD.

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Validated HPLC columnsA technical reportfrom Mac-ModAnalytical discussesthe interpretationand significance oftest chromatogramssupplied with com-mercial HPLC col-umns. The reportalso includes anoverview of thehistory of column-to-column repro-ducibility and dis-cusses a method ofcolumn and batch

validation that calls for using a variety of acidic, basic,and neutral test probes under different mobile phaseconditions. Mac-Mod Analytical Inc., Chadds Ford, PA.

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GC accessoryThermo Orion’s EZFlash GC accessory isdesigned to converta conventional GCsystem to a fast-GCsystem. The acces-sory uses a GCsystem’s injection,detection, and datasystems and allowsthe capillary columnto be heated atrates as high as 20 °C/s, withambient tempera-ture control to

400 °C. Thermo Orion, Beverly, MA.

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Evaporative light-scattering detectorRichard Scientific’sSedex 75 evapora-tive light-scatteringdetector includes a nebulizer thatreportedly is opti-mized for LC–MSapplications inwhich low solventflow rates arenecessary and issuitable for aqueousand organic solventflow rates as high as4 mL/min. Appli-cations include

analysis of glycerides, lipids, polymers, andcarbohydrates. Richard Scientific, Inc., Novato, CA.

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Laboratory workstation

The Sonication workstation from Zymark is designedfor use with the company’s Prelude sample prep-aration system. The workstation can be used to dis-perse samples such as powders, tablets, creams, gels,and ointments. Users can select time, probe intensity,probe depth, and temperature for unattendedsample extraction. Zymark Corp., Hopkinton, MA.

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SPE phases

Strata Screen mixed-mode SPE sorbents fromPhenomenex are designed for extracting drugs ofabuse from biological fluids. The sorbents areavailable in straight-barrel tubes, 20-mL funnel-shaped tubes, and 96-well plates. Phenomenex Inc.,Torrance, CA.

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Polymer characterizationCirrus multidetectorsoftware fromPolymer Labo-ratories is designedfor polymercharacterization byGPC. The softwareallows users toacquire and analyzedata from GPCsystems fitted withas many as fourrefractive index,light-scattering, andviscosity detectors.Users can calculate

molecular weight, intrinsic viscosity, and radius ofgyration as a function of elution volume using avariety of data-fitting options. Polymer LaboratoriesInc., Amherst, MA.

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TLC abstractsCAMAG’s Bibli-ography Servicebrochure includes166 abstracts ofrecent publicationsabout planar andthin-layer chroma-tography (TLC). Theabstracts aregrouped into 37classificationsaccording to tech-nique, application,and sample com-pound. The bro-chure contains

application notes and a section of TLC hints. CAMAGScientific, Inc., Wilmington, NC.

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Flash chromatography system

The Flash 40 flash chromatography system fromLabAlliance consists of one or two pumps with amaximum flow rate of 40 mL/min, a fixed-wavelengthUV–vis detector with a preparative cell, an injector,and a keypad controller that can store 10 gradientmethods, link to a shut-down method, and receiveexternal commands. LabAlliance, State College, PA.

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Environmental wet chemistry analyzerEST Analytical’sKonelab analyzer isdesigned forautomated analysisof water andwastewater samplesin environmentalwet chemistrylaboratories. Asmany as 84 samplesand six prioritysamples can beloaded into theanalyzer withoutinterruptingongoing analyses.

The device’s software provides automatic dilutioncapability and enables users to run as many as 200tests/h. The instrument monitors reagent levels in realtime. EST Analytical, Cincinnati, OH.

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Spicy-food analysisAn application note from Restekdescribes using thecompany’s Ultra C18 HPLC columnfor determination ofcapsaicinoid contentin spicy foods. Fig-ures and chromato-grams illustrate thecolumn’s perform-ance during sep-aration and quanti-tation of threetarget capsaicinoids.The note discusses

the history of heat-level determination and explainsvarious uses for spicy foods and extracts. RestekCorp., Bellefonte, PA.

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Data management and reporting A brochure fromShimadzu describesthe VP Archive datamanagement systemand VP Office sys-tem for displaying,analyzing, andreporting data. Thepublication discussesfeatures such as VPArchive’s context-sensitive keys andVP Office’s dataformatting capa-bilities. The bro-chure lists

specifications and minimum requirements for the Microsoft Windows–based systems. ShimadzuScientific Instruments, Inc., Columbia, MD.

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GPC–SEC systemA brochure fromViscotek discussesthe company’s GPC–SEC system. Thepublication includesdescriptions of thesystem’s compo-nents, includingthree detectors — a light-scatteringdetector, a four-capillary differen-tial viscometer, anda differentialrefractometer — aswell as aqueous and

organic columns, standards, and Microsoft Windows–based software. Viscotek, Houston, TX.

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GC–MS system

Leco’s Pegasus 4D GC–time-of-flight MS system pro-vides mass spectral acquisition rates as high as 500 spectra/s. The instrument includes the company’sChromaTOF software, which provides mass spectraldeconvolution algorithms for identifying and quant-ifying target analyte data. Leco Corp., St. Joseph, MI.

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Power supply

The Constant Current power supply from DETectorEngineering is designed to provide heating currentand polarization voltages for ion sources used in GCnitrogen–phosphorus detection and thermionic ion-ization detectors. The module reportedly provides aheating current of 0–4 A and polarization voltages of 25, 215, and 245 V. DETector Engineering & Tech-nology, Inc., Walnut Creek, CA.

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Column selectorDesigned forcooling and heatingLC columns, thePower-Selectorautomated columnselector fromAnalytical Sales andService has amicroprocessor-based temperaturecontroller thatmaintains temper-atures within a 5–60 °C range withrepeatability pre-cision of �0.1 °C

and accuracy of �1 °C. Analytical Sales and Services,Mahwah, NJ.

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Ion analyzerThe DX80 ionanalyzer fromDionex is designedfor analyses of ionsand cations. Theanalyzer includes amanual injectionport, a polymericflow path, a heatedcell, and continuoussuppression capa-bility using thecompany’s MMS IIIsuppressor. Thedevice’s recipro-cating PEEK pump

has a single set of check valves and seals to minimizemaintenance costs. Dionex Corp., Sunnyvale, CA.

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HPLC autosamplerD-Star’s DAS-10HPLC autosamplerhas four modes ofoperation: manual,automated, auto-mated manualtrigger, and timed.Programmingoptions enable usersto enter samplesize, number andposition of samplesin the carrousel, andnumber of injec-tions for each vialposition. D-Star

Instruments, Inc., Manassas, VA.

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Microwave digestion system

PerkinElmer’s Multiwave 3000 is designed for high-throughput, microwave-assisted sample preparation.The system’s software includes a methods library withU.S. Environmental Protection Agency procedures andprocess control, data collection, and calibrationfunctions. PerkinElmer Instruments, Norwalk, CT.

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Data-management software

NuGenesis Technologies’ SDMS version 5.2 data-management software includes an archival tooldesigned to enhance integration with existing data-base security and maintenance protocols. Accordingto the company, users can access the path of dataprogression without limitations from different filetypes or multiple locations. NuGenesis TechnologiesCorp., Westborough, MA.

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A/D conversion moduleScientific Software’s SS420x analog-to-digital (A/D)conversion module provides remote acquisition for asmany as four channels of data. The instrument hasfour triggers and eight relays for programmableswitching applications. LED status indicators on theinstrument show start-up, data acquisition,reprogramming, and error status. Scientific Software,Inc., Pleasanton, CA.

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Chromatography productsA catalog from Wheaton Science Products lists thecompany’s laboratory products. Chromatographyproducts include columns, autosampler andheadspace vials, vial selectors, crimpers anddecappers, mobile-phase reservoirs, and TLCglassware. Wheaton Science Products, Millville, NJ.

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GPC softwareViscotek’s TriSECversion 3.0 softwareis designed for usewith the company’striple-detectorsystem for GPC.Available modulesinclude conven-tional calibration,GPC–viscometry for universal cali-bration, light-scattering–tripledetection, co-polymer analysis,

and automation and batch processing. Viscotek,Houston, TX.

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HPLC systemA brochure fromHitachi Instrumentsdescribes the com-pany’s LaChromHPLC system, whichincludes a gradientpump, a program-mable autosampler,a column oven, adiode-array detec-tor, and softwarepackages designedfor research anddevelopment. Thepublication includesinformation about

the company’s System Manager software for instru-ment control, Validation Manager software for sys-tem validation, and ChromSword Auto software forautomatic method development. Hitachi Instruments,Inc., San Jose, CA.

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LC–MS columnsA brochure fromAnsys Technologiesdiscusses the com-pany’s Polaris LC–MScolumns. Accordingto the publication,the columns arestable in 100%aqueous conditionsand are availablefor applicationsranging from high-throughputscreening to prepa-rative-scale sepa-rations. Ansys

Technologies, Inc., Lake Forest, CA.

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Capillary column data sheetA data sheet fromVICI Gig Harbordiscusses the com-pany’s VB-1 capillaryGC column, which isdesigned for theanalysis of amines,flavors and frag-rances, hydro-carbons, and sulfurcompounds. Thepublication includesa chart that listsavailable innerdiameters, filmthicknesses, and

temperature limits for the three available columnlengths. VICI Gig Harbor Group Inc., Gig Harbor, WA.

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Ion-mobility spectrometerBarringer’s Ionscan-LS ion-mobilityspectrometer isdesigned foridentifying andquantifying tracechemicals inpharmaceutical andchemical labo-ratories. The high-throughput instru-ment selectivelyionizes organiccompounds andseparates them bytime of flight.

Typical analysis time is 6–20 s, and new targetanalyses reportedly can be programmed into theinstrument within minutes. Barringer Instruments,Warren, NJ.

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HPLC productsA catalog fromZirChrom discussesthe company’szirconia-based HPLCproducts. The pub-lication includes adescription of thecompany’sDiamondBond HPLCcolumns and acomparison guide toHPLC columns andcolumn efficiencies.ZirChrom Sepa-rations, Inc., Anoka,MN.

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Syringe filters

Cameo syringe filters from Osmonics are availablewith nylon, PTFE, and polypropylene membranefilters in polypropylene housings. The filters areavailable in pore sizes of 0.10, 0.22, 0.45, 1.2, and 5.0�m. Osmonics Laboratory Products, Minnetonka, MN.

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HPLC system

Shimadzu’s model LC-2010A HPLC system is designedfor high-throughput applications. The integrated sys-tem includes a high-speed autosampler, a columnoven, and a 190–600 nm UV–vis detector. ShimadzuScientific Instruments, Inc., Columbia, MD.

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DNA control samplesAmbion’s ArrayControl system is a set of DNA controlsamples used for printing and controlling RNAtranscripts for hybridization. The system is designedto normalize and validate gene array data. Users canmonitor reverse transcription, cDNA labeling,hybridization stringency, and background. Ambion,Inc., Austin, TX.

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Microplate sealing systemThe MicroMat CLR 96- and 384-well microplatesealing system from Sun International is made ofclear, chemically resistant silicone. The resealablesystem, which is designed to resist coring and tearing,is available with preslit penetration areas for samplepipetting that reportedly reduce the formation of avacuum in microplate wells. Sun International,Wilmington, NC.

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Microwave GC column oven

A microwave GC column oven from Antek Instru-ments is designed to perform simulated distillation of light distillates in less than 3 min and can be usedwith columns as long as 60 m. The oven is compatiblewith laboratory and process GC systems. AntekInstruments, Inc., Houston, TX.

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Reversed-phase HPLC columns

Supelco’s Discovery HS reversed-phase HPLC columnswith 3-, 5-, and 10-�m dp media are designed forpharmaceutical analysis and purification. Availablephases include a nonpolar C18 phase for LC–MS, apolyethylene glycol phase for phenolic compoundanalysis, and a pentafluorophenyl phase for analyzingbasic and halogenated compounds. Supelco, Inc.,Bellefonte, PA. �

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Documents

HPLC method development Chromatography productsfiles.pharmtech.com/alfresco_images/pharma/2014/08/...instrument holds as many as 12 microplates and has ... Plate cap mat and heating