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How do we study brain/behavior relationships?. Populations: Animal Models: advantages:disadvantages:. Human Models. populations with injuries or disease normal populations. Humans. History: phrenology:. Non-invasive ways of viewing brain function. Assessment of Structure vs Function. - PowerPoint PPT Presentation
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Populations:
◦ Animal Models:
advantages:disadvantages:
populations with injuries or disease
normal populations
History:
◦ phrenology:
Assessment of Structure vs Function
CT or Cat Scan
CT Scan
CT or Cat Scan
◦3 D xrays
CT or Cat Scan
MRI's
magnetic resonance imaging
CT
MRI
EEG - electroencephalogram
EEG – electroencephalogram
◦ ERPs – evoked related potentials
PET scans◦ rCBF – regional cerebral blood flow
Premise – more blood flow means more (neuronal) activity
PET scans◦ rCBF
◦ 2DG – 2 deoxyglucose Premise – need for more sugar – need for more
energy – more (neuronal) activity
PET scans◦ rCBG
◦ 2DG
fMRIs
Histological analysis
Lesion studies ◦ Rationale – if an area is damaged and behavior
changes….. the neurons in that area play a role?
Electrical stimulation
◦ Rationale: if we stimulate an area and we produce or stop a particular behavior….the neurons in that region are important for that behavior
Delgado’s classic experiment
Electrical stimulation
Pharmacological manipulations◦ Use of drugs and various agents
Microdialysis- looks at the amount of neurotransmitter released in a region of the brain….