High Efficiency Cardiac System for Cardiac Therapy

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    HIGH EFFICIENCY CARDIAC

    SYSTEM FOR CARDIAC THERAPY

    -AMOL PARAB

    -VIKRAMADITYA DANGI-KSHITIJ PAWAR

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    HUMAN HEART

    1)Muscular organ responsible for pumping blood through blood vessels byrepeated , rhythmic contractions.

    2) cardiac comes from Greek word KARDIA related to the heart

    3)Average human heart 72 BMP ( 2.5 billion times in 66 yrs)

    4) It is effectively a meshwork of cardiac muscle cells interconnected by

    contiguous cytoplasmic bridges

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    Need for Circulation

    1) To deliver food materials and oxygen to the

    tissues

    2) To remove waste products and heat

    3) Done by diffusion in small animals, but in largeanimals its a must

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    Functioning

    1) Right side collects deoxygenated blood in the right atrium

    and pumps it into the lungs via right ventricle

    2) CO2 , O2 by process of diffusion

    3) Left side -- collects oxygenated blood in the left atrium andpumps it back into the body via left ventricle

    4) Arteries supply the pure blood

    5) Veins collect impure blood

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    NEED FOR CARDIAC THERAPY

    To avoid :

    1) ARRHYTHMIAS

    2)MYOCARDIAL INFARCTION

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    ARRHYTHMIAS

    1)An arrhythmia is a problem with the speed or rhythm of the

    heartbeat.

    2) A heartbeat that is too fast is called tachycardia

    3) A heartbeat that is too slow is called bradycardia.

    4)Common among older adults

    5) Causes : heavy alcohol, smoking

    6) Symptoms : Shortness of breath

    Chest pain

    Arrhythmic palpitations

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    Myocardial Infarction

    1)Myocardial infarction, commonly referred to as a heart attack,

    occurs when one or more coronary arteries become suddenly

    blocked, resulting in heart muscle death.

    2) Myocardial infarction results from coronary artery disease (CAD),

    which is an accumulation of plaque inside the coronary blood vessels.

    3) When one of these plaques rupture, a clot forms rapidly at the site

    and causes a sudden obstruction of blood flow in the coronary artery.

    4)Symptoms : Shortness of breath and chest pain

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    TREATMENT

    1)Angioplasty is the technique of mechanically widening a narrowed or

    obstructed blood vessel

    2) An empty and collapsed balloon on a guide wire, known as a balloon

    catheter is passed into the narrowed locations and then inflated to a

    fixed size using water pressures some 75 to 500 times normal blood

    pressure (6 to 20 atmospheres).

    3) The balloon crushes the fatty deposits, opening up the blood vesselfor improved flow, and the balloon is then deflated and withdrawn.

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    Problems with traditional methods

    1) Large size

    2) Poor efficiency (less than 20 %)

    3) Away from surgical area

    4) Use of co-axial cables resulting in power losses of 6 dB

    5) Solid-state devices (smaller size) but generated heat

    These problems can be solved by using microwave devices whichgenerate less heat and only heat the desired tissue without affecting

    the surroundings .

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    MICROWAVE ENERGY GENERATOR

    CONCEPT

    1) Microwave energy sources for cardiac surgery must be

    capable of delivering up to 80 Watts at 2.54 GHz.

    2) The primary technology for these sources is vacuum-tube

    3) Artisan Laboratories Corporation has developed a new

    microwave source called Ultralight Microwave Energy Source

    for generating, amplifying, distributing and controlling

    high power microwave energy for cardiac surgery.

    4) In addition their concept allows for the use of optical fiber for

    distribution of control signals. Using a fiber optic cable for

    signal distribution has many benefits over coaxial cables

    including: low loss, high isolation, small size, improved

    flexibility.

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    Continued..

    1)The microwave input signal is compared against a

    reference signal in a pulse width modulator (PWM)

    generator.

    2)The output is a pulse-width modulated signal

    that drives an optical transmitter and is directed to a

    microwave photonic amplifier via a fiber optic cable.

    3)The optical PWM signal is used to drive the high efficiency

    microwave photonic amplifier that converts the signal back to

    microwaves

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    CONTINUED..

    1)The design and fabrication of the system consisted of building

    three main circuits: PWM Generator, Laser Transmitter andthe Microwave Photonic amplifier.

    2)The PWM generator uses a high speed comparator to convert the analog

    or microwave signal to a PWM.

    3) The PWM output is used to modulate a laser transmitter and the resultingsignal is transmitted over a fiber to the microwave photonic amplifier

    4) They achieved 80 % maximum efficiency with 55 %

    power added efficiency at a level of 100 mW.

    COMPUTER AIDED DESIGN OF

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    COMPUTER AIDED DESIGN OF

    MINIATURIZED ANTENNAS FOR

    MICROWAVE CARDIAC ABLATION

    1) In this methods of designing miniaturized antennas for the application

    of microwave ablation for the cure of cardiac arrhythmias.

    2) Finite Difference Time Domain and Finite Element methods are used to

    first design and optimize miniaturized antennas.

    3) The overall size of the antennas has 2.5mm outer diameter that is

    suitable for intravenous catheterization delivery.

    4) Bioheat transfer equation is solved using finite difference method and its

    predicted temperature results are compared with the results obtained from

    the experiments.

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    CONTINUED..

    1)Cardiac ablation refers to the procedure of destroying

    myocardial tissue that is responsible for causingarrhythmias.

    2)This procedure utilises external electromagnetic energy to raise

    the local temperature of the problematic site that originates the

    arrhythmia to produce a lesion so that the conduction of

    undesirable electrical signal is eliminated.

    3)Over the past years, the radio-frequency (RF) had become a

    popular mode of energy delivery system for cardiac ablation.

    4)However, one of the disadvantages of RF ablation is that it

    requires constant contact between the RF electrode and themyocardium tissue.

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    Continued..

    1) In contrast to RF energy, microwave energy causes dielectric heating by

    stimulating the oscillation of dipoles within the myocardium.

    2) Taking the advantage of this property, microwave antenna is capable

    of depositing energy deep within the myocardium and hence obtaining greater

    lesion depth than RF ablation.

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    Continued

    1) During the ablation procedure the temperature differences

    are usually more than 1 O"C, therefore, the temperature

    dependent nature of the myocardium tissue's dielectric

    constant is an important factor and must be

    considered during modelling.

    2)Once the near-Electric-field values of the antenna are

    obtained, the Specific Absorption Rate (SAR) is calculated.

    3)Using the calculated SAR, one is able to predict the

    temperature profile of the antenna by applying the Bio-HeatTransfer Equation (BHE) and solved by using the FD

    technique.

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    Continued..

    1)A novel coaxial slot array antenna is extensively analysed and tested using the

    FDTD technique.

    2)Overall, the CSA antenna is capable of generating temperatures of greater than

    55 degrees required forirreversible lesion formation in a very short period of time.

    3)The lesion sizes, in terms of width and depth, are controlled by varying the

    microwave energy and ablation duration. In relatively short periods of ablation

    time, the CSA antenna is capable of producing lesions of sufficient depth for

    transmural atrial ablation. In some cases, transmural ventricular ablation is also

    achieved.

    4) Thus optimum temperature can be obtained.

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    MICROWAVE TOMOGRAPHY

    1) Microwave tomography is a novel, early development stage imaging modality

    with a number of potentially attractive biomedical applications.

    2) A high contrast between properties of normal and diseased tissue

    is a great potential of this imaging modality.

    3)With microwave tomography tissues are differentiated and, consequentially,

    can be imaged, based on differences in dielectric properties.

    4)It has been proven in a number of studies that dielectric properties of biological

    tissues are a strong indicator of its functional and pathological

    conditions.

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    Continued..

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    Continued..

    1) The system operates at frequencies of 0.9-1.0GHz.

    2) The operation frequency can be changed within the optimum

    spectrum for tomographic imaging.

    3)The working chamber consists of a cylinder with diameter of 120cm and

    height of 135cm, filled with matching solution.

    4)In microwave tomographic experiments the object under study is placed

    into the central part of the working chamber, which is filled

    with matching solution.

    5) The major purpose of the matching solution is to decrease the high

    reflection of EM fields from the air-body boundary. Various types of

    matching solutions have been used: deionized water, saline and fattysolutions with dielectric constants varying in between 40-

    80 at room temperature.

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    DIATHERMY

    1) In the natural sciences the term diathermy means "electricallyinduced heat" and is commonly used for muscle relaxation.

    2) It is also a method of heating tissue electromagnetically or

    ultrasonically for therapeutic purposes in medicine.

    3) Surgical diathermyis usually better known as "electrosurgery

    4) Electrosurgery and surgical diathermy involve the use of high

    frequency A.C. electrical current in surgery as either a cutting

    modality, or else to cauterize small blood vessels to stop

    bleeding.

    5) This technique induces localized tissue burning and damage, the

    zone of which is controlled by the frequency and power of the

    device.

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    Continued..

    1) Diathermy involves current frequencies between 400KHz to 10MHz, thus

    allowing currents of 500mA to safely pass through patient (100mA at a

    household frequency of 50Hz will cause electrocution.

    2)Monopolar diathermy

    Electrical plate is placed on patient and acts as indifferent electrode

    Current passes between instrument and indifferent electrode

    As surface area of instrument is an order of magnitude less than that of

    the plate

    Localized heating is produced at tip of instrument

    Minimal heating effect produced at indifferent electrode

    3) Bipolar diathermy

    Two electrodes are combined in the instrument (e.g. forceps)

    Current passes between tips and not through patient

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    Microwave diathermy

    1) Its frequency is 27,120,000 cycles per second and the

    wavelength is 11 metre

    2) High frequency waves are generated by Magnetron

    1) Circuit Description: Diathermy machine consist o f two main

    circuits ;an oscillating circuit, which produces the high

    frequency current and a patient circuit which is

    connected to the oscillating circuit and through which the

    electrical energy is transferred to the patient.

    2) Uses: pain bacterial infection boils

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    Continued..

    More uses:

    1.Inflammation of shoulder joint

    2.Inflammation of Elbow Joint (Tennis Elbow)

    3.Degeneration of joints of neck (Cervical Spondylosis)

    4.Degeneration of joints like knee and hip (Osteoarthritis)

    5.Ligament Sprains in knee joint

    6.Low Back Ache

    7.Plantar fascitis (Heel Pain)

    8. Sinusitis

    SIE METHOD OF ANALYSING

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    SIE METHOD OF ANALYSING

    MICROWAVE FIELDS

    OF A 3D HEART MODEL1) There are several important factors when using microwaves devices

    (wavelengths of 10 cm to 1 mm) which will determine their successful

    application in medical procedures.

    2) The first factor is the wavelength of the microwave may be of the same order as the

    size of the tissue to be incinerated and permits us to eliminate only the unhealthy

    tissue.

    3)The second factor is the MC used for ablation is very minute and when using

    this procedure it greatly diminishes the risks of many complications as

    compared to traditional surgical operations.

    4) The third factor is that when doctors monitor a patient using microwaves devices

    like ours he can keep informed of the patients vital signs such as blood pressure

    and pulse

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    Continued..

    1 Our SIE method was used for the numerical analysis of a

    microwave electric field on a heart model when a MC was placed

    inside.

    2. We have seen that our SIE method enables one to optimal the size

    and shape of a MC when used to remove abnormal tissue in the

    heart.3. The imaginary parts of the permittivities of the heart media are

    quite large; this causes the attenuate of the microwave energy in

    the media. We see that the amplitude of the electric field decreases

    while moving away from the MC tip.

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    Continued

    4. We see that the microwave electric field distribution

    inside of the heart model depends on the shape and

    location of the microwave catheter.

    5. We discovered that the electric field distribution most

    suitable for microwave ablation is when a curved microwavecatheter is pressed against the top lateral surface of left

    heart cavity. In this case the electric field distribution in the

    transversal cross-section has only one maximum which

    means that the electric field is concentrated

    only on the tissue to be removed. Also the magnitudes of

    electrical field distribution in the longitudinal cross sectionof the heart model are less than in other cases

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