Ground Glass Lesions

• Fibrous Dysplasia• Chronic Sclerosing

Osteomyelitis• Osteitis Deformans (early

phases)• Hyperparathyroidism• Osteopetrosis

Fibrous Dysplasia

• Childhood Onset• Growth cessation at Puberty• Expansile, Nondemarcated• Bone panel is normal• Cosmetic Osseous Contouring• Monostotic or Polyostotic

Fibrous Dysplasia

• Monostotic• Polyostotic• McCune-Albright

– Polyostotic– Endocrinopathies– Café au Lait Pigmentation– Mutation with Lyonization

Fibrous Dysplasia

Fibrous Dysplasia

FD - diffuse margins

Fibrous Dysplasia

Fibrous Dysplasia

Chronic Sclerosing Osteomyelitis

• Childhood onset• Bacterial infection

– anaerobic• ? Source – odontogenic• Poorly marginated• Episodic Pain• Culture/Sensitivity

Chronic Sclerosing Osteomyelitis

Chronic Sclerosing Osteomyelitis

Osteitis Deformans (Paget’s)

• Elderly• Polyostotic Lesions• Progressive Opacification• Cranial Nerve Deficits• Alkaline Phosphatase• Normal Calcium• Giant Cell Tumors• Sarcomas

Osteitis Deformans

Osteitis Deformans

Osteitis Deformans• Mosaic Bone

Hyperparathyroidism

• Primary Parathyroid Adenoma• Secondary to Renal Disease• Diffuse, Poorly Marginated• Loss of Lamina Dura• Hypercalcemia, Calciuria• Brown Tumors• Urolithiasis

HyperparathyroidismRenal Osteodystrophy

Osteopetrosis (Marble Bone)Albers-Shonberg Disease

A diverse group of diseases genotypically with a commonPhenotype

Defective osteoclastic resorption

Inherited as automsomal dominant or recessive

Mutations in Carbonic anhydrase II, subunit of vacuolar protein pump of the brush border, cathepsin K (Pycnodysostosis)

Diffuse ground glass opacification that may obscure theImage of teeth radiographically

Myelophthisic anemia with thrombocytopenia

Osteopetrosis