HEPATITIS B SURFACE ANTIGEN PREVALENCE IN THE OUTPATIENT

ADULT HIV POPULATION IN

GABORONE, BOTSWANA

Premal Patel MD MSc, Stephanie Davis MD,

Michael Tolle MD MPH, Vincent Mabikwa,

Gabriel Anabwani MD

Baylor International Pediatric AIDS Initiative

Botswana-Baylor Children’s Clinical Centre of

Excellence Gaborone, Botswana

Background

• Hepatitis B and HIV Coinfection

• Hepatitis B Prevalence in SSA

• Botswana HIV Treatment Guidelines

Methods

• Retrospective review of the EMR

• Patients between the ages of 18 to 80 were screened for Hepatitis B (HBsAg) from 2005 to 2009

• HBSAg results from 268 patients

Results

1 3 5 7 9 11 130

20

40

60

80

100

120

Transaminases in HbSAg + Patients

AST

ALT

Patient Number

Un

its/

L

• Overall HBsAg Prevalence: 5.2%• Transaminitis: 3/14 (21.4%)

Conclusion• Limitations

– Retrospective Study– HBsAg testing only– Female Predominance

• Botswana-Specific Context:– Significant Prevalence– Access to resources– Availability of TDF/FTC in public sector (1st line)

• Routine HBsAg screening as part of the Botswana National HIV Guidelines

AcknowledgementsPatients and Staff at the BBCCOE

Stephanie Davis MD

Michael Tolle MD MPH

Vincent Mabikwa

Gabriel Anabwani MD

Matthew Dacso MD MSc

Parth Mehta MD

Baylor International Pediatric AIDS Initiative

Pediatric AIDS Corps

Baylor College of Medicine