Text of Hemophilia A By Marissa Miuccio. Hemophilia A Also known as Factor VIII Deficiency is the most...
Hemophilia A By Marissa Miuccio
Hemophilia A Also known as Factor VIII Deficiency is the most common type of hemophilia It is a disorder of your blood-clotting system Clotting is the process which your blood changes from a liquid to a solid state It is largely an inherited disorder in which one of the proteins needed to form blood clots is missing or reduced. In about 30% of cases, there is no family history of the disorder and the condition is the result of a spontaneous gene mutation.
Hemophilia A When a person with hemophilia is injured, he does not bleed harder or faster than a person without hemophilia, he bleeds longer. Small cuts or surface bruises are usually not a problem, but more traumatic injuries may result in serious problems and potential disability (called "bleeding episodes").
Normal plasma levels of FVIII range from 50% to 150% There are different levels of hemophilia: mild, moderate, and severe, depending on the amount of clotting factor in the blood: People with mild hemophilia have 6% up to 49% of the normal clotting factor in their blood. Most patients usually have problems with bleeding only after serious injury, trauma or surgery. In many cases, mild hemophilia is not diagnosed until an injury, surgery or tooth extraction results in prolonged bleeding. The first episode may not occur until adulthood. Women with mild hemophilia often experience menorrhagia, heavy menstrual periods, and can hemorrhage after childbirth.
Continued People with moderate hemophilia about, 15% of the hemophilia population, have 1% up to 5% of the normal clotting factor in their blood. They tend to have bleeding episodes after injuries and some without obvious cause. These are called spontaneous bleeding episodes. People with severe hemophilia about 60% of the hemophilia population, have