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Health Tech Showcase Silicon Valley Bank, 15 March 2017 @SVB_UK #SVBpitch

Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Page 1: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

Health Tech Showcase

Silicon Valley Bank, 15 March 2017

@SVB_UK #SVBpitch

Page 2: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

@SVB_UK #SVBpitch

Agenda: 15 March 2017

12.00 – 13.00 Lunch and networking

13.00 – 13.10 Welcome and overview of SVB/DIT commitment to the UK tech sector

Nooman Haque, Silicon Valley Bank Paul Morris, Department for International Trade (DIT)

13.10 – 13.35 Keynote speaker Dr Francesca Wuttke, Managing Director, Merck Global Health

13.35 – 14.15 Pitches from early stage health tech businesses 13.35 – 13.42 Touch Surgery 13.43 – 13.50 CareZapp 13.51 – 13.58 Intelesens 13.59 – 14.06 Medopad 14.07 – 14.14 Howz 14.15 – 14.22 Bodytrak 14.25 – 15.00 Tea and coffee break with networking 15.00 – 15.40 Pitches from growth stage health tech businesses 15.00 – 15.07 Ieso Digital Health 15.08 – 15.15 Cydar 15.16 – 15.23 Oxehealth 15.24 – 15.31 Lumeon 15.32 – 15.39 Perspectum Diagnostics 15.40 – 15.45 Closing remarks

15.45 – 17.00 Networking, one to one meetings and refreshments

Upcoming DIT and Silicon Valley Bank Pitch Showcase Events

Sector Location Date

Big Data/Analytics London: Silicon Valley Bank 05 July 2017

Virtual Reality & Artificial Intelligence

London: Silicon Valley Bank 27 September 2017

Cybersecurity

London: Silicon Valley Bank 22 November 2017

Page 3: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Nooman Haque Managing Director, Life Science and Healthcare, Silicon Valley Bank Nooman Haque is the Managing Director of Life Science & Healthcare with Silicon Valley Bank’s UK Branch. Nooman is responsible for developing new relationships, identifying lending opportunities and working with the global life sciences team to support companies with all aspects of their business. He is actively involved within the sector, sitting on the BIA’s Finance and Tax Committee, and is a frequent participant on panel and seminars.

Nooman joined Silicon Valley Bank from a venture capital firm in London and previously ran a sovereign wealth fund in Saudi Arabia largely focused on healthcare. His background includes strategic and financial advisory, debt and equity structuring and risk management. Nooman has a Bsc in psychology and Msc in economics, both from the University of London, and an MBA (finance) from Imperial College. He is a member of the British Psychological Society and the Royal Economic Society.

Paul Morris Department for International Trade (DIT) Paul Morris is a 20-year veteran of the Corporate Venture Capital industry. He set up and ran the CVC operation of Dow Chemical in Europe and has been at the forefront of new CVC initiatives for many years. He has invested over $100M in 35 direct deals and, as an LP, in 15 VC funds. During a 28-year career with Dow, Morris held senior business management roles across various geographies, including Head of New Businesses for EMEA.

Paul now consults for corporates, governments, start-ups and funds on CVC, investments and fundraising, and delivers training for Corporate VCs. He currently leads venture capital investor interactions for the UK government’s Venture Capital Unit. The VCU connects CVCs and VCs from around the world with pre-screened UK start-ups seeking funding.

Page 4: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Francesca Wuttke, Ph.D Managing Director Merck Global Health Innovation Fund

Francesca Domenech Wuttke, Ph.D is a Managing Director focused on identifying new investment opportunities in Europe for the Merck Global Health Innovation Fund, LLC. Dr. Wuttke brings with her broad drug development and healthcare expertise in both the US and Europe, with over 20 years of clinical, commercial, strategic and transactional experience. She has worked with diverse organisations including start-ups, consulting, large and specialty pharma, as well as academia.

Most recently Dr. Wuttke led Almirall’s Corporate Development Strategy team to transact on both medical device and pharma M&A opportunities with a new and targeted focus for the company.

Before that, Dr. Wuttke worked at Novartis where she was responsible for two Cell and Gene therapy opportunities that were successfully brought into the organisation, as well as managing the strategy and commercialisation for the existing portfolio of cell therapy assets.

Dr. Wuttke holds a Ph.D in Pharmacology from Weill Cornell Graduate School of Medical Sciences, and a BA from Cornell University College of Arts and Sciences.

About Merck Global Health Innovation Fund

Merck Global Health Innovation Fund (GHI) provides growth capital to healthcare technology companies worldwide while leveraging the vast R&D-based, global resources of Merck. The fund invests in breakthrough healthcare solutions that advance Merck’s mission to discover, develop and provide innovative products and services to save and improve lives.

Founded in 2010, the fund has made more than 30 investments in digital health and has $500 million under management. For more information, please visit www.merck.com/ghi.

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@SVB_UK #SVBpitch

About DIT Venture Capital Unit The UK is the number-one destination for foreign direct investment in Europe – second in the world only to the USA. A recent survey of international business leaders found investor confidence in the UK is the strongest in Europe1, whilst the World Bank has said it is easier to do business here than any other major economy in the continent. Put simply, the UK is one of the most attractive places to invest globally across diverse sectors. The DIT Venture Capital Unit helps promote and drive more investment into UK innovation, either through direct investments into UK companies, setting up a new UK-based fund, or investment into an existing UK fund.

Venture capital investment in the UK is growing rapidly with a record £3.5bn of investment in 20152. The VCU is building on this momentum and supports investors worldwide in capitalising on UK innovation opportunities. We do this by:

• Facilitating connections between investors and innovative UK companies seeking early and growth stage capital;

• Providing a bespoke service to investors who are poised to invest in the UK, through tailored investment opportunities and pitching events; and

• Marketing the UK as the venture capital destination of choice. DIT/VCU sends out a bimonthly newsletter to a targeted audience. This includes a case study, news, figures, upcoming events in the industry, and links. We invite investors to contact us if they wish to be added to our mailing list. In addition, our brochure can be accessed here: https://www.gov.uk/government/publications/ukti-venture-capital-unit. For further information on how the Venture Capital team at DIT can support you, please contact [email protected] or [email protected].

1 A.T. Kearney 2014, Foreign Direct Investment Confidence Index: Ready for Takeoff 2 http://www.cityam.com/231820/

Page 6: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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About Silicon Valley Bank

Page 7: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

@SVB_UK #SVBpitch

Early stage: Early revenues or Pre Series A

Touch Surgery has built a surgical simulation training platform used by over 1.7M people, making it the world’s largest online surgical community.

Learn more: www.touchsurgery.com

CareZapp is a collaborative platform for providers of home care and support, empowering a holistic network to enable more effective and affordable outcomes.

Learn more: www.carezapp.com

Intelesens has developed a portfolio of intelligent, wireless, non-invasive vital signs monitoring devices for hospital and home patient markets.

Learn more: www.intelesens.com

Medopad is transforming how healthcare providers, doctors and patients connect with each other, with remote patient monitoring apps and mobile technology.

Learn more: www.medopad.com

Howz is a new connected home system that measures a household’s usage of electricity to create a pattern of daily behaviour that can inform care networks.

Learn more: www.howz.com

Bodytrak is setting a new standard of wearable technologies monitoring vital signs and activity precisely in real time from one smart device worn in the ear.

Learn more: www.bodytrak.co

Page 8: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Growth stage: £1M+ revenues or Series A+

Ieso Digital Health provides evidence-based mental health therapy online, using an analytics platform to connect patients with practitioners.

Learn more: www.uk.iesohealth.com

Cydar uses high performance cloud computing to provide surgical guidance in the operating room, combining diagnostic scan with real-time imaging.

Learn more: www.cydarmedical.com

Oxehealth turns cameras into health monitors, allowing doctors to screen for previously unscreenable conditions.

Learn more: www.oxehealth.com

Lumeon is a digital health company that has defined the market for Care Pathway Management, automating the clinical and patient journey.

Learn more: www.lumeon.com

Perspectum Diagnostics was founded in partnership with the University of Oxford and has commercialised groundbreaking technology for liver disease. Learn more: www.perspectum-diagnostics.com

Page 9: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Company name: Touch Surgery Year founded: 2013 HQ location: London, United Kingdom Company website: https://www.touchsurgery.com/ Contact details: Lauren Temple ([email protected]) Presenter name and title: Dr. Andre Chow, Co-founder and CEO Company description: At TOUCH SURGERY we believe in building technologies to empower the global surgical community. We are working with leading surgical minds from around the world, to map and share the language of surgery. Our surgical simulation training platform is used by over 1.7m people. The app is currently free to download and available from both Apple’s App Store and Google’s Play Store. Over 60% of our current users are medical professionals, which makes us the world’s largest online surgical community. We generate revenue by partnering with medical device manufacturers who want to sponsor training modules on the Touch Surgery platform, showcasing their tools. Industry partners pay us a one-off fee for the build of specific modules as well as on-going monthly maintenance and data package fees. For our partners, the value in working with Touch Surgery lies in both the access to the audience on the platform and unique data that gets generated by users interacting with sponsored modules. Key customers: Johnson & Johnson/Ethicon, Stryker Orthopaedics, Smith & Nephew, Zimmer Biomet, Cardinal Health Key milestones achieved and growth:

• Research-validated platform for surgical training • 1.7M+ downloads • 380K+ module attempts and 16K+ hours of simulated surgery per month

Management team and key experience:

• CEO – Dr. Andre Chow, Dr. Jean Nehme • COO – Eric Collins • CTO – Paul Ryan • Head of R&D – Danail Stoyanov • Head of Engineering – James Kellerman

Funding to date: $12M What are you looking to get out of today? Connect with growth investors, raise awareness of the Touch Surgery product and company Funding required: Interested to speak with investors about future raises

Page 10: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Company name: CareZapp Year founded: 2014 HQ location: Dublin, Ireland Company website: http://www.carezapp.com/ Contact details: Andrew Macfarlane ([email protected]) Presenter name and title: Andrew Macfarlane – Co-Founder & CEO Company description: CareZapp is a new kind of collaborative platform for innovative providers of home care and support, empowering a holistic network to enable more effective and affordable outcomes. Working with innovative home care and support providers, CareZapp provides a holistic approach to new care models, empowering better care and greater independence. Connecting people across the formal and informal networks to help share the care. Enabling virtual care services by aggregating data from IoT devices, utilising our intelligence engine to better inform care 24/7. Key customers: IE: Myhomecare.ie / Myhomecare Connect / Leading home care provider in Ireland UK: Cornerstone / Largest third sector care provider in Scotland USA: Pilot project with Western Michigan University & Clark Retirement Communities Key milestones achieved and growth:

• Bank of Ireland Accelerator (Sep ’14) • TechCrunch Disrupt Finalists (Oct’14) • Enterprise Ireland CSF / Funding (Dec ’14) • Various paid trials/pilots in Ireland, UK and the USA (2015-16) • Enterprise Deal with Cornerstone, Scotland (Dec’16, ACV 100k+)

Management team and key experience:

• CEO – Andrew Macfarlane, Serial Health Tech Entrepreneur • CCO – Frank Mutel, Large scale projects in the EU and USA • CTO – Carl Flynn, Corporate web projects, Entrepreneur

Funding to date: $80k funding to date via the Founders ($25k), Accelerator / Enterprise Ireland ($55k) What are you looking to get out of today? Follow up meetings with potential investors with a keen interest in the sector / opportunity Potential partnerships opportunities related to technology, utility or care partners Funding required: Looking to raise $850k seed round, closing Q2 2017 Current commitments of $200k via EI HSPU

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Company Name: Intelesens Limited Year founded: 2009 (Pivot and relaunch) HQ location: 17 Heron Road, Belfast, BT3 9LE Company website: www.intelesens.com Contact details: Aidan Langan ([email protected]) Presenter name and title: Aidan Langan, CEO Company description: Intelesens was founded and spun out of Ulster University by the late Prof John Anderson and Prof Jim McLaughlin. Intelesens is an established medical technology company that has developed a portfolio of intelligent, wearable, non-invasive, wireless vital signs monitoring devices for the hospital and home patient monitoring markets. Building on proprietary high sensitivity arrhythmia and respiratory algorithms and software developed in collaboration with research and clinical partners, the company has created a robust technology platform that is increasingly being used to improve patient care, reduce diagnosis times, provide re-assurance to patients and help deliver significant healthcare savings. Our products are unobtrusive for patients, intuitive for nurses and effortless for clinicians. Independent market research predicts that the patient monitor market will grow from $11 billion in 2015 to $26 billion by 2022 driven by increasing reliance on multi-parameter patient monitors in every bed of every hospital, in multiple areas of specialised clinics and in many rehab centres. Intelesens products are regulatory approved in the EU and USA and are currently deployed in both the hospital and home settings. Key customers: South Eastern Health and Social Care Trust – Ulster Hospital Hospital Corporation of America – TriStar Centennial Medical Centre Key milestones achieved and growth:

• FDA Approval • First Successful sale to NHS hospital July 2015 • First deployment in US Hospital June 2016

Management team and key experience:

• Chairman – David Ataide, Chief Marketing Officer, Philips Healthcare • CEO – Aidan Langan, ex CEO of Enterprise Equity • CFO – Deirdre Francis ex FD of Minready solutions • CTO – Prof Jim McLaughlin, Founder and Director of NIBEC

Funding to date: Various rounds £6 million What are you looking to get out of today? Currently fundraising for £2.5 million target. Also seeking a strategic partner to build hospital sales worldwide. Funding required: £2.5 million

Page 12: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Company name: Medopad Ltd. Year founded: 2011 HQ location: 78 Buckingham Gate, Buckingham Court, St. James Park, SW1E 6PE London Company website: www.medopad.com Contact details: [email protected] Presenter name and title: Dr Rich Khatib - CEO Company description: Medopad transform how healthcare providers, doctors and patients connect with each other. The company’s remote patient monitoring apps, mobile technology and advanced analytics unite to deliver a personalised, more efficient care experience. Headquartered in London, Medopad is CE approved and FDA registered. Clients include Barts Health NHS Trust, Royal Free London NHS, HCA, Bayer, national healthcare providers and global pharmaceutical organisations. Medopad’s AI division is leveraging the latest machine learning technologies to address the challenges associated with disease detection, preventative healthcare and patient misdiagnosis. Key customers:

• National Health Service • HCA International • UMG • Bayer

Key milestones achieved and growth:

• $100bn+ Size of digital health market 2026 • 30% QoQ Total average value of won contracts • $1.5m+ Projects signed in the past 6 months • International scaling EU, US, China

Management team and key experience:

• CEO – Rich Khatib • CTO – Dan Vahdat

Funding to date: US$6m What are you looking to get out of today? Investment and networking Funding required: A Round US$6m

Page 13: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Company name: Howz Year founded: Intelesant Ltd incorporated September 2012 HQ location: Manchester Science Park, Manchester Company website: www.howz.com Contact details: Jonathan Burr, [email protected], 07768 005740 Presenter name and title: Jonathan Burr, Founder & CEO Company description: Howz is a new connected home system that measures a household’s usage of electricity and combines this with information from a series of sensors that detect door movement, temperature and light levels in a person’s home, to build up a pattern of daily behaviour. Howz uses statistical principles and machine learning to identify unusual activity or trends and notify a person’s care network, using predictive analytics and a knowledge of frailty and functional decline to give early warning of trends that could develop into a serious situation. Predominantly aimed at elderly people, typically living alone, the system has been created to empower the individual to let their care network know they are safe, warm and well. The rollout of 53 million smart meters offers a way to deploy Howz at national scale at low cost by working with the energy sector. Howz is very actively involved in research with the NHS including: 2 NHS Test Beds: TIHM Surrey (dementia) and LCIA Lancashire (COPD); the Christie (prostate and blood cancers); Greater Manchester AHSN (stroke); and Salford Royal FT (frailty). Key customers: EDF Energy, Manchester City Council, Bolton City Council, Surrey & Borders Partnership NHS FT, Lancashire Care NHS FT, Christie NHS FT Key milestones achieved and growth:

• February 2017 - Winner EDF Energy Pulse Award for Connected Home and Business • April 2016 - GM AHSN research grant - stroke • January 2016 - Surrey and Lancashire Test Beds • November 2015 - Finalist Pitch @ Palace

Management team and key experience:

• Jonathan Burr (CEO) 18 years’ experience in finance, key account sales, business development, mergers and acquisitions (Avis, GE Capital). Formerly Chief Operating Officer at ITIS Holdings plc and developed the world’s first commercial floating car data system. Jonathan is a chartered accountant.

• Louise Rogerson (Clinical and Operations) 18 years’ experience of working in the NHS in clinical, operational and commissioning roles. Louise is a chartered neurophysiotherapist.

• Nina Embleton (Technology and Data Science) Nina has a BSc in Mathematics (First Class Honours) from Newcastle University, an MSc in Applied Mathematics (Distinction) from Herriot-Watt University and a PhD in Applied Mathematics from Birmingham University.

Funding to date: £1.4m What are you looking to get out of today? Create further awareness and meet potential investors Funding required: £2M

Page 14: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Year founded: 2013 HQ location: London (Innovation Warehouse, 1 East Poultry Avenue, London EC1A 9PT) Company website: www.bodytrak.co Contact details: [email protected], 07500 012635 Presenter name and title: Leon Marsh, Founder & CEO Company description: Bodytrak® is the next generation in wearable technology. With the steady decline of sales in wrist-based wearables, the ear is the new location set to transform the industry with a growth of over 2500% annually. With a much better signal-to-noise ratio than the wrist, significant improvements can be made to reliability and accuracy. Bodytrak is the first solution to implement precision physiology monitoring into a compact earpiece providing automated real-time data and powerful cloud-based analytics, utilising both machine learning and intelligent algorithms to give unrivalled real-time insights to enable marginal gains and greater success as well as early intervention to reduce risk and associated insurance premiums. It is the only device to be able to measure core body temperature unobtrusively and as accurately as medical devices. This provides significant advances in the monitoring of elite athletes, industrial workforces, fire fighters, soldiers and patients. Bodytrak also measures heart rate and motion and provides two-way communications, which means Bodytrak can determine, for example, when someone has fallen and how urgent a recovery is, whilst enabling a response team to communicate with the user directly. The largely enterprise focused model will be monetised through a subscription PaaS model via direct and partner channels. Key customers:

• Professional sports teams in premiership football, rugby and cycling, who are trialling Bodytrak. • A major oil & gas provider and a utility company who will both trial the technology in 2017. • Scott Safety, who have ~50% US market share of the first response and industrial sectors for

breathing apparatus. The team at Bodytrak is invited to join Scott for a US expo to demonstrate the technology to their customers.

• The MOD, who have funded development work and who will be trialling the technology • Racal Acoustics (supplier of communication headsets). Bodytrak intends to produce a

demonstrator with Racal to take to their customers. • Ultra & Fujitsu. Bodytrak has already participated in providing a demonstrator for defence use. • Fire & Rescue Services, who are trialling Bodytrak.

Key milestones achieved and growth:

• £200k revenue from MOD development contracts, £650k grants • 22 field trials commencing with customers across all sectors – sport, defence, first response,

industrial, healthcare • Very successful PR launch at the Consumer Electronics Show in Las Vegas early January with an

award for ‘best performance tracker in show’ and over 50 international publications - Android Headlines, Wired, The Verge, Mobi Health News & Evening Standard

• Technology validation against medical gold standard devices by two universities • Pilot clinical trials kicking off with Chelsea & Westminster Hospital in Summer 2017, funded via

a grant

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• Partnered with Flextronics as sub-contract manufacturer • Full beta maturity of the hardware and platform, with design for manufacture underway • Worldwide patent granted and several others pending • Team of 8 (7 FT) with a further 2 identified, covering management, commercial and engineering,

and 3 key sector advisors in addition Management team and key experience:

• CEO - Leon Marsh (BSc) is the founder and driving force behind Inova and inventor of the technology. He spent 10 years as an Industrial Designer with Philips and Nokia, working across design, innovation, product development and manufacturing in the UK, mainland Europe and the Far East. He has raised over £2.6m through grants, contracts and investment, and developed relationships with multi-national and high profile corporations in sport, defence, industrial and healthcare sectors. His ambition is to deliver end-to-end solutions to Bodytrak users who will experience improvements to their health and well-being.

• CFO - Geoffrey Drage (OBE, FCA) trained as an investment banker in the City and has held directorships in private and government organisations for over 25 years, and was awarded an OBE in 2009 for services to intellectual property. He is now actively involved in technology commercialisation, corporate governance, finance and strategy, and undertakes mentoring of early stage technology ventures.

• CTO - Ed Ang (BEng, PhD) obtained a PhD from Imperial College London, specialising in biomedical signal processing and designing algorithms for automated patient monitoring in the healthcare context, and leads algorithm development for applications including sport, defence and healthcare. He has published in numerous journals and conference papers, including the British Medical Journal.

• CSO - Alec Creighton (BSc, MBA) has held senior management positions in both the private and public sectors in both the USA and the UK. In the private sector, Alec focused on developing, maintaining and farming key commercial accounts in the banking sector. In the public sector, Alec was responsible for three key services in primary care as well as developing business strategies for securing funding from multiple public domains.

Funding to date: £2.6m total: £1.7m investment (with a corporate investor as lead), £650k grants, £200k MOD development contracts, £60k Founder savings. What are you looking to get out of today? Investment, as outlined below. Funding required: £1.5m required in order to reach production, gain CE mark, complete the market validation phase (field trials with high profile customers), continue to grow the internal team, and gear up for an early growth round and international expansion (US initially).

Page 16: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Company name: Ieso Digital Health Year founded: 2011 HQ location: The Grange, High Street, Swavesey, Cambridgeshire, CB24 4QG Company website: http://uk.iesohealth.com Contact details: 01954 230066, [email protected] Presenter name and title: Dr Andy Blackwell, Chief Scientific Officer and President of EU Operations Company description: Ieso Digital Health provides evidence-based mental health therapy online. Only 15% of all people with anxiety and depression are able to access services and new approaches are needed. Our mission is to make high quality therapy available on demand to anyone who needs it.

Ieso uses a web-based therapy delivery and analytics platform to connect patients with fully trained and accredited practitioners. Based on objective assessment of clinical needs, patients are matched to a specific provider and evidence-based, recovery-focused, clinical protocol that is appropriate for the condition (and severity). The platform includes a clinical measurement framework and anonymised data are reported publically and also used to inform clinical supervision – helping providers to continuously improve the quality of care delivery.

Ieso is now the largest digital provider of mental health treatments in the UK (>10,000 patients treated in 2016) and has is currently rolling out operations in the USA.

Key customers: UK – NHS England (Clinical Commissioning Groups & Trusts) US – Leading Behavioural Health Provider with c.50m lives Key milestones achieved and growth: 2009: Clinical evidence published in The Lancet 2011: 1st fund raised - Early NHS pilot projects 2012: Commissioned NHS Surrey 2013: 2nd fund raised

2014: 3rd fund raise - Ieso clinical data show better recovery than the IAPT national average (52% vs 46%) and higher levels of therapy completion (60% vs 40%) achieved at 50% fewer sessions than face-to-face therapy.

2015: Appointment of Dr Andy Blackwell as CSO and Julian Coe as CFO. Referral volumes exceed 500 patients per month for first time. Letter of Intent signed with leading US Behavioural Health Provider with c.50m lives.

2016: Appointment of US behavioural health leader Dan Clark (formerly Optum, Humanna and Aetna) as Group Chief Executive. 10,000 patients now treated by Ieso patient volumes exceed 1,000 referrals per month in the UK. First contract in US commenced with 500 referrals. First AI driven product protocol introduced.

2017 ytd: Appointment of Mike McGreal, (formerly Beacon Health Options) as US Chief Operating Officer. Obtain ISO 27001 accreditation for Information Security Management for UK.

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Management team and key experience:

• Simon Cartmell OBE – Executive Chairman Simon Cartmell is a 35 year the life-sciences industry veteran. He has pharmaceutical, biotech and med-tech experience gained in commercial, product development, supply chain, strategic leadership and corporate executive roles. Simon is a serial entrepreneur in early stage healthcare businesses.

• Dan Clark, President & CEO Dan has a rich background in behavioural health. He is a mental health counsellor by training and has not only started two successful, technology-enabled healthcare service businesses, but has also led the scaling, innovation and growth of companies ranging from smaller seed-stage companies, to major Fortune 50 organisations.

• Dr Andy Blackwell, Chief Scientific Officer and President of EU Operations. Andy brings a unique combination of clinical and scientific expertise in mental health and neuroscience together with business acumen gained in the digital health sector in the UK and USA. Andy sits on the board of Cambridge Cognition Plc, holds a PhD in Cognitive Neuroscience from the University of St. Andrews and spent several years at the Department of Psychiatry at the University of Cambridge.

• Mike McGreal, Chief Operating Officer US Operations Mike McGreal is the former COO and EVP at Beacon Health Strategies, which recently merged with Value Options to create Beacon Health Options, a large managed behavioural healthcare leader in the US with 50 million members. As EVP and Chief Operating Officer for the majority of his tenure, he was responsible for business operations including operations strategy development and implementation for the company.

• Barnaby Perks, Founder & Exec VP of Corporate Development Barnaby joined Ieso Digital Health in January 2011 following publication of clinical trial data in the Lancet. He has developed the company from its beginning as a research project, to become a proven commercial platform operating at scale in the UK National Health Service (NHS).

• Julian Coe, Chief Financial Officer Julian has put in place the infrastructure for the company to scale and grow, looking at back office systems and processes and how the firm is organised financially and operationally to ensure maximum efficiency. From 2000-2007 he was first Financial Director and latterly Chief Executive of Altrix Healthcare plc which developed a range of innovative solutions for the public sector. Funding to date: Date Stage Company Valuation Invested 6/2011 Seed 1.081.000 € 590.000 € 6/2013 Seed 3.122.500 € 1.320.000 € 6/2014 Seed 5.091.000 € 1.045.000 € 11/2015 Expansion/Growth 10.084.000 € 4.128.500 € Shareholders/investors: Cambridge Angels / Imperial Innovations / Ananda Social Venture Fund What are you looking to get out of today? Connections with investors and commercial partners and the opportunity to explain our company differentiation. We hope to provide interested parties with insight on how digital health providers will succeed in penetrating existing markets and displacing traditional providers. Funding required: Series A – 15.000.000 €

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Company name: Cydar Year founded: 2012 HQ location: Cambridge Company website: www.cydarmedical.com Contact details: [email protected] Presenter name and title: Tom Carrell, CEO and Co-Founder Company description: Cydar is the first company in the world using high performance cloud computing to provide surgical guidance in the operating room. At its core, fully-automatic computer vision tracks patients during X-ray guided surgery: enabling it to combine diagnostic scan, planning information and real-time imaging with millimetre precision. With measurable impacts: reducing operating time, radiation exposure of patients and staff, and reducing use of kidney-toxic iodine compounds. The company is now scaling both geographically and into expanded clinical applications, as well as using its unique access to combined diagnostic, planning, guidance and surgical result data to provide new insights and value for health systems. Key customers: Duke University Medical Centre, US Royal Free Hospital, London Guy’s and St Thomas’ Hospitals, London Key milestones achieved and growth:

• First company to connect operating rooms imaging to the cloud, 2014 • FDA clearance of cloud computer vision powering 3D image fusion, 2016 • First US contract, 2017

Management team and key experience:

• CEO – Tom Carrell • CFO – Fiona Kinghorn • CTO – John Clarke • CSO – Graeme Penney (co-founder)

Funding to date: £4.3m What are you looking to get out of today? Meet investors active in both healthcare and cloud SaaS Funding required: £7.2M

Page 19: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Company name: Oxehealth Year founded: 2012 Company website: www.oxehealth.com HQ location: The Sadler Building, The Oxford Science Park, Heatley Road, Oxford, OX4 4GE Presenter name and title: Hugh Lloyd-Jukes, CEO ([email protected]) Company description: Oxehealth turns cameras into health monitors. The technology can be used to monitor traditional health markers (e.g. heart rate & breathing rate) totally contact free, through standard digital cameras, with medical grade accuracy. Oxehealth can also monitor human activity, behaviours and safety. New video health markers are being developed which will allow doctors to screen for previously unscreenable conditions. Oxehealth is building a unique deep learning-enabled big data platform. Cameras will become a critical “Internet of Things” sensor in delivering the Population Health solutions required to deal with the crisis in developed world health systems; Oxehealth’s technology will power these solutions. As one medical director remarked recently, “your technology will change the practice of medicine”. Our software is currently being deployed to monitor safety and health in police, mental health and hospital settings but it we see it being deployed in a wide range of settings including nursing & elderly care and community & home care. Venture Capital backed, Oxehealth was founded by the Head of Engineering at Oxford University, Professor Lionel Tarassenko. Key customers: Metropolitan Police Coventry & Warwickshire Partnership NHS Trust Key milestones achieved and growth:

• Clinical Studies 2012-2014 (John Radcliffe & Churchill Hospitals, Oxford) • Field Studies 2015 & 2016 (Broadmoor, Metropolitan Police) • First pilot sale December 2016 • First clinical development partnership January 2017

Management team and key experience:

• CEO – Hugh Lloyd-Jukes, serial entrepreneur, trained as strategy consultant • CFO/COO – Simon Hardman, Management Accountant, successful exits for PE & VC-backed

businesses, Shell trained • CTO – Ben Wensley-Stock, prominent technologist including leading role in delivering NHS Spine,

serial entrepreneur Funding to date: £4.7MM What are you looking to get out of today? Start relationship building for future funding requirements Funding required: Oxehealth will be looking to raise growth capital in the near future

Page 20: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Company name: Lumeon Year founded: 2005 HQ location: 10 Leake Street, London SE1 7NN Company website: www.lumeon.com Contact details: [email protected] Presenter name and title: Andrew Wyatt, COO Company description: Lumeon is a digital health company that has defined the market for Care Pathway Management (CPM).

Lumeon's Care Pathway Management platform orchestrates and automates the clinical and administrative patient journey across the care continuum. Its workflow automation can be configured to reduce readmissions and improve clinical and operational efficiencies which are vital to the transition to value-based care and bundled payment models.

Lumeon’s next generation digital patient engagement solutions (via email, app or web-based experiences) to help monitor and proactively support patient populations using intelligent automation.

Lumeon Analytics provides self-service analytics across any clinical or financial dimension of the care pathway, including PROMs (patient recorded outcome measures).

Today, the Lumeon CPM platform has been proven in a large number of large-scale healthcare organisations allowing real-time tracking of millions of patient journeys.

Key customers: Bupa Nuffield Health Alliance Medical HCA Optegra Synexus Newmedica One-Stop-Doctors Six Physio Key milestones achieved and growth:

• 2012 Bupa comes on board as a customer • 2015 6m B series funding • 2017 US office opening

Page 21: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Management team and key experience:

• CEO – Robbie Hughes Robbie is the founder and CEO of Lumeon. An engineer by training, he started Lumeon when he identified a need within the healthcare industry for a different approach to how healthcare software technology should be built. Under Robbie’s leadership, Lumeon has grown from his bedroom with a business funded by individual clients, to an enterprise-level solution that is currently in use by 65 major healthcare providers and growing.

• CFO – Andrew Wyatt Andrew has 25 years of leadership experience in global B2B software and has been instrumental in scaling numerous innovative businesses into highly successful enterprises. These include Lotus Development Corporation Inc., Paragon Software Ltd., Openwave Inc. and Apertio Ltd. Most recently, Andrew was VP of Strategy for BroadSoft Inc. (NASDAQ: BSFT).

• CTO – Kelvin Klibbon Kelvin has 17 years’ experience in technology and joined Lumeon from Powa Technologies, a leading e-commerce provider, where he was Head of Engineering and Implementation. He has led product commercialisation strategies, ensured successful roadmap delivery and managed teams across England, Hong Kong and Poland. Kelvin also held senior positions at Neverfail, Clearswift, Intuwave and Apertio.

• General Manager (US) Larry Roshfeld

An expert in business and product strategy, and experienced in growing start-ups and established companies, Larry heads Lumeon’s USA division. With more than 20 years’ experience in the technology sector, Larry has helped build start-ups including Riverbed Technologies, (acquired for $1.1 billion by Aether Systems) Approva, CorasWorks, CivicUS Research and Sonatype at CEO and VP level. He was an executive at Lotus Development and IBM, and co-founded Trigon Health, a provider of prescriptive analytics software for healthcare.

Funding to date:

• £4m A Series - Amadeus, Archimedia • £6m B Series - Amadeus, Archimedia Gilde Healthcare

What are you looking to get out of today? Like-minded investors who have a view to US expansion. Funding required: ~£8m C Series

Page 22: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Company name: Perspectum Diagnostics Year founded: 2011 HQ location: Oxford, UK (37 FTE) Raleigh NC, USA (4 FTE) Company website: perspectum-diagnostics.com Contact details: [email protected], +44 1865 261 457 Presenter name and title: Dr. Rajarshi Banerjee BM BCh, MA, MSc, MRCP, DPhil, Chief Executive Officer Company description: Perspectum Diagnostics is a medical imaging company founded by scientists and physicians from the University of Oxford. It has pioneered the use of quantitative magnetic resonance imaging (MRI) to accurately detect and measure biomarkers of liver disease. The Company’s proprietary technology and flagship product, LiverMultiScan, is available for clinical use in the USA and Europe and is offered as a Quantitative Analysis Service. Data collected from MRI scans across customer sites are sent securely to Perspectum’s dedicated reporting centre, analysed and returned as patient-friendly reports to physicians. Perspectum provides continuous support with regular quality checks and continuous access to its clinical applications team. The Company’s research tool, LiverMultiScan Discover, offers an advanced analytical platform that includes Perspectum’s proprietary metric, the Liver Inflammation and Fibrosis (LIF) score. LiverMultiScan Discover is currently supporting clinical studies, particularly in non-alcoholic steatohepatitis (NASH). Unlike the Company’s closest competitors, LiverMultiScan (Discover) works accurately on all patient types including the obese cohort, which are at the highest risk for developing serious liver complications. LiverMultiScan (Discover) is running across 5 continents, not only providing non-invasive and cost-effective solutions for physicians and pharmaceutical companies, but also improving patient welfare. Key customers: Pharma and Biotech (including Intercept, Novartis, Galectin, Tobira, AbbVie, Eli Lilly); CROs (including Quintiles, VirtualScopics, MedPace); over 50 hospitals globally

Page 23: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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Key milestones achieved and growth:

• LiverMultiScan is the only non-invasive liver test that predicts clinical outcomes • FDA clearance and CE-marking; invited into Transatlantic FDA/EMEA working group • US commercial operations established

Management team and key experience: CEO - Dr. Rajarshi Banerjee BM BCh, MA, MSc, MRCP, DPhil has pioneered quantitative liver imaging for clinical use. His medical research work in liver disease, as well as extensive experience in running clinical trials whilst working in multidisciplinary scientific teams to develop applications for cutting-edge imaging technology, ideally positions him to lead innovation in his field. During his PhD at the University of Oxford, he founded Perspectum Diagnostics along with Professor Sir Michael Brady, Professor Stefan Neubauer and Professor Matthew Robson.

CFO – Tracey Morton FCMA LLM is a Fellow of the Chartered Institute of Management Accountants (FCMA), as well as a Chartered Global Management Accountant (CGMA). She provides leadership for Finance, IT and Procurement functions within the organisations and her financial qualifications are supplemented by a Masters degree in Business Law.

Chairman - Professor Sir Michael Brady FRS FREng FMedSci is Professor of Oncological Imaging in the Department of Oncology at the University of Oxford, having retired as Professor of Information Engineering. Apart from his research in medical imaging, he is a serial entrepreneur, having founded Mirada Solutions, Guidance, Matakina, and Mirada Medical. He was a NED of Dexela Ltd, and is also Chairman of Acuitas Medical Ltd, IRISS Medical Ltd, Colwiz Ltd, and is Deputy Chairman of Oxford Instruments plc. In addition to his role as Chairman of Perspectum, Mike leads the image analysis team. Funding to date: $10m What are you looking to get out of today? Liver disease is big business, and a huge unmet need. Drug development is hampered by the lack of ways to determine efficacy and outcomes, and to find the patients who would benefit from the new drugs. Perspectum solves that problem. We want to be the mainstream clinical test for liver disease, available from your nearest hospital (MRIs are everywhere now, we are a cloud-based software add-on to an MRI scan). We want to find a strategic investor who is willing to put in part of $30m for us to finance a full penetration of the clinical (not pharma) North American market. Funding required: $30m

Page 24: Health Tech Showcase - Silicon Valley Bank Health Tech... · Big Data/Analytics London: Silicon Valley Bank 05 July 2017 Virtual Reality & Artificial ... Managing Director, Life Science

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