HC70A Winter 2006Genetic Engineering in

Medicine, Agriculture, and Law

Professor Bob Goldberg

Class Announcements 2/14/06

Crisis in US Science & Technology

HC70AL Spring 2006Gene Discovery Laboratory

Professor Bob GoldbergM 6-8

TTh 2-6

Send Me An Email Indicating That You Would Like To

Take the Lab and HaveA “Real-Life” Science Experience

Go Tohttp://www.mcdb.ucla.edu/Research/Goldberg/

HHMI_Program/hc70al.html

Take-Home Exam& Oral Mid-Term Exam

•Exam Out - Today

•Questions Due - 3/2

•Mid-Term Oral - 3/2

•Rules & Fail Safe

Discussion Tomorrow

•Play -When Science Takes the Witness Stand -- DNA Testing & Criminal Cases

Law School

Murphy Hall

Review of Last Lecture

•How Do DNA & Genes Replicate?

•Genetic Engineering & The PCR Revolution!

•Kerry Mullis & PCR - The Movie!

•The Double Helix

Text Reading

•Chapter 2 - Genes & Gene Activity

•Chapter 4 - Proteins

•Chapter 11 - Medical Biotechnology

Handout Reading

•The Molecular Genetics of Hemophilia**

•Your Genes Your Choices

•Genomes.Org - The Human Genome Project Information

•Should We Make a Fuss? A Case for Social Responsibility in Science

•Rising Above the Gathering Storm & Is America Flunking Science?

Today•Mutations, Pedigrees, & Genetic

Diversity•Genes To Proteins

•Gene Activity in Bacteria & Eukaryotes

•One Gene-Many Proteins-Relevance to Humans & Chimps!

•The Genetic Code & Genetic Engineering•DNA vs. RNA

•Yo-It’s All in the Sequences!-Modules & Genetic Engineering!

•From Pedigree To Gene To Drug-A Case Study-Hemophilia