Guide for Self-Injectionwith WhisperJECT™

Autoinjector (Rx Only)

INDICATIONGLATIRAMER ACETATE INJECTION is a prescription medicine used for the treatment of people with relapsing forms of multiple sclerosis (MS).

IMPORTANT SAFETY INFORMATIONDo not take GLATIRAMER ACETATE INJECTION if you are allergic to glatiramer acetate or mannitol. Some patients report a short-term reaction right after injecting glatiramer acetate. This reaction can involve flushing (feeling of warmth and/or redness), chest tightness or pain with heart palpitations, anxiety, and trouble breathing.

Please see additional Important Safety Information on the back cover. Please see the full Prescribing Information, including Patient Information Leaflet and Instructions for Use. Please see the Instructions for Use provided with your WhisperJECT™ Autoinjector device.

This self-injection guide does not take the place of talking with your doctor about your medical condition or treatment.

Features of the The WhisperJECT™ Autoinjector is intended for use with FDA-approved drug products with non-viscous (aqueous) liquid formulations, which are presented in a 1.0 mL BD®, pre-filled, glass syringe with staked needle, containing a fixed needle of 27G to 29G. The WhisperJECT™ Autoinjector is a reusable injection device for the subcutaneous injection of certain FDA-approved drugs.

The WhisperJECT™ Autoinjector device has features that have been designed by patients, for patients.

Textured handle designed for a good grip and steady injection

Large viewing windows on front and back to give you a visual confirmation when your injection is complete

Needle shield that hides the needle during injection

Please see the Instructions for Use provided with your WhisperJECT™ Autoinjector device.

The WhisperJECT™ Autoinjector is available by Rx only.

7 Possible Injection AreasThere are 7 possible injection areas. Select a different area each time you inject.

Each injection area contains multiple sites for you to choose from. Avoid injecting in the same site more than 1 time each week.

Glatiramer Acetate Injection is for under the skin (subcutaneous) injection only; do not inject into your veins (intravenously).

*Stomach area around the belly button.

Please see additional Important Safety Information on the back cover. Please see the full Prescribing Information, including Patient Information Leaflet and Instructions for Use. Please see the Instructions for Use provided with your WhisperJECT™ Autoinjector device.

Back of Upper

Right Arm

Back of Upper

Right Hip(below waist)

Front of Right Thigh

(above knee)

Back of Upper

Left Arm

Abdomen*

Back of Upper

Left Hip(below waist)

Front of Left Thigh

(above knee)

Our patient website was created to help you learn more about your medication and the support services available to you:

• Medication and autoinjector information

• Patient support program and co-pay assistance eligibility details

• Self-injection information and resources

• Mylan Smart Injection Tracker™ app

• Rotation Plan to record injection details

• Injection Preparation Mat for your supplies

• Links to MS community resources

Start learning more at GlatiramerAcetate.com.

All patients enrolled in the Mylan MS Advocate™program will receive a Welcome Pack that

includes an instructional DVD.

To view this instructional video online, visit GlatiramerAcetate.com

Additional online resources View the instructional video

Guide for Self-injectionwith WhisperJECT™ Autoinjector Rx Only

Mylan MS Advocate™ is your patient support program to help you with your Mylan’s Glatiramer Acetate Injection therapy.

MS-experienced nurses work with you one-on-one to:

• Go through the injection process step by step to help you learn proper injection techniques

• Help you adjust your routine based on lifestyle changes such as changes in weight

• Provide you with tips regarding preparation, administration, storage and disposal of your medicine

• Offer you tools for tracking self-injections

• Connect you to supportive MS resources and encourage you to participate in the MS community

• Assist you in connecting to a support network

For more information about your patient support program, refer to Mylan’s Glatiramer Acetate Injection Patient Brochure in your Mylan MS Advocate™ Welcome Pack.

Here when you need us!

1.844.MylanMS (1.844.695.2667)

• Keeping a record of your injection sites helps avoid injecting in the same sites more than once each week

• You may choose to record the day and injection site on your mobile Mylan Smart Injection Tracker™. Please visit GlatiramerAcetate.com for more information on the app, or to download the PDF of the Rotation Plan

• See additional information in the enclosed self-injection training DVD and in the Injection Help section of the GlatiramerAcetate.com website

Please see additional Important Safety Information on the back cover. Please see the full Prescribing Information, including Patient Information Leaflet and Instructions for Use. Please see the Instructions for Use provided with your WhisperJECT™ Autoinjector device.

Recording the Day and Injection SiteVisit the App StoreSM or Google Play™ to download your free Mylan Smart Injection Tracker™ to record your injections with Mylan’s Glatiramer Acetate Injection.

Mylan MS Advocate™, WhisperJECT™, Mylan Smart Injection Tracker™, and Mylan’s Glatiramer Acetate Injection logo are trademarks of Mylan Pharmaceuticals Inc.. The Mylan logo is a registered trademark of Mylan Inc. BD® is a registered trademark of Becton, Dickenson and Company. App StoreSM is a service mark of Apple Inc. Google Play™ is a trademark of Google Inc.

©2017 Mylan Pharmaceuticals Inc. All rights reserved. GA-2017-0019

IMPORTANT SAFETY INFORMATIONDo not take GLATIRAMER ACETATE INJECTION if you are allergic to glatiramer acetate or mannitol.

Some patients report a short-term reaction right after injecting glatiramer acetate. This reaction can involve flushing (feeling of warmth and/or redness), chest tightness or pain with heart palpitations, anxiety, and trouble breathing. These symptoms generally appear within minutes of an injection, last about 15 minutes, and do not require specific treatment. There have been reports of patients with similar symptoms who received emergency medical care. If symptoms become severe, call the emergency phone numbers in your area.

Call your doctor right away if you develop hives, skin rash with irritation, dizziness, sweating, chest pain, trouble breathing, or severe pain at the injection site. If any of the above occurs, do not give yourself any more injections until your doctor tells you to begin again.

Chest pain may occur either as part of the immediate post-injection reaction or on its own. This pain should only last a few minutes. You may experience more than one such episode, usually beginning at least one month after starting treatment. Tell your doctor if you experience chest pain that lasts for a long time or feels very intense.

A permanent indentation under the skin (lipoatrophy and, rarely, death of your skin tissue also referred to as necrosis) at the injection site may occur due to local destruction of fat tissue. Be sure to follow proper injection technique and inform your doctor of any skin changes.

The most common side effects in studies of GLATIRAMER ACETATE INJECTION are redness, pain, swelling, itching, or a lump at the site of injection, flushing, rash, shortness of breath, and chest pain. These are not all of the possible side effects of GLATIRAMER ACETATE INJECTION. For a complete list, ask your doctor or pharmacist. Tell your doctor about any side effects that you have while taking GLATIRAMER ACETATE INJECTION.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information, Patient Information Leaflet and Instructions for Use for GLATIRAMER ACETATE INJECTION 20 mg/mL or GLATIRAMER ACETATE INJECTION 40 mg/mL.