Otsuka Holdings was established on July 8, 2008 as a holding company for the Otsuka Group to improve overall Group corporate

value. Otsuka Holdings will support the sustainable growth of Group companies, maximize the Group’s synergies by integrating

management resources, increase management efficiency, and empower employees and organizations.

Established in 1964, Otsuka Pharmaceutical is a total healthcare company. In keeping with its corporate philosophy of “Otsuka-people creating new products for better health worldwide,” the company aims to care for people's overall health not only by treating illness, but also by sustaining day-to-day well-being. Otsuka Pharmaceutical operates a pharmaceutical business to provide new therapeutic agents, as well as a nutraceutical business to provide products that help people lead healthier and more active lives.

Established in 1963, Taiho Pharmaceutical is a pioneer in the field of oral anti-cancer agents and is known in Japan as “Taiho, the anti-cancer drug maker.” The company has also been developing unique and novel drugs in the fields of allergies, immunology and urology. In the consumer healthcare field, Taiho Pharmaceutical’s product brands have been loved by consumers for decades. Based on its corporate philosophy, “We strive to improve human health and contribute to a society enriched by smiles,” Taiho Pharmaceutical aspires to be an agile specialty pharmaceutical company that is trusted the world over.

Otsuka Pharmaceutical Co., Ltd. Taiho Pharmaceutical Co., Ltd.

Group Structure & Overview of Main Operating CompaniesOtsuka-people creating new products for better health worldwide

Group structure(as of December 31, 2014)

Otsuka Holdings

Otsuka Pharmaceutical

Otsuka Pharmaceutical Factory

Taiho Pharmaceutical

Otsuka Warehouse

Otsuka Chemical

Otsuka Medical Devices

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In addition to providing product storage and logistics within the Group, Otsuka Warehouse distributes products to market for the Otsuka Group as well as for other firms. In recent years, Otsuka Warehouse has increased the percentage of its non-Group sales to over 50% through its strategy of promoting a common distribution platform for the three product areas of pharmaceuticals, food and beverages, and daily necessities. The company has also been forming partnerships with firms such as a leading instant noodle manufacturer and a pharmaceutical company. As a result of these efforts of this kind, the company received the Logistics Grand Prize (Management Innovation Award) in 2013, the most prestigious accolade in the Japanese logistics industry.

Otsuka Chemical has been developing a range of businesses since 1950. These include operations in hydrazine-related business such as foaming agents, a fine chemicals business handling materials such as pharmaceutical intermediates, and a materials business that supplies titanate and engineering plastics compounds. Its corporate philosophy is, “Trusted by individuals, Trusted by the company, Trust is the dream of our society. Building trust with technology and commitment. Spreading trust with the people around the world.” True to this philosophy, Otsuka Chemical is working creatively with customers to realize the full potential of chemical materials.

Otsuka Medical Devices was established in 2011 to oversee the Otsuka Group’s medical device businesses. One such enterprise is JIMRO, which manufactures and sells Adacolumn, an apheresis device for granulocyte adsorption in inflammatory bowel disease. Other businesses include Achieva Medical and Microport Scientific, both located in Shanghai, China, as well as Era Endoscopy based in Pisa, Italy. Then there is KiSCO, which focuses on orthopedic implant devices for spinal disease. Otsuka Medical Devices is expanding its businesses globally, and aspires to become one of the Group's core businesses.

Otsuka Pharmaceutical Factory, Inc.

Otsuka Warehouse Co., Ltd.

Otsuka Chemical Co., Ltd.

Otsuka Medical Devices Co., Ltd.

Founded in 1921, Otsuka Pharmaceutical Factory is the original company of the Otsuka Group and meets a wide range of needs with its innovative products, including intravenous solutions, rehydration beverages, and medical foods. It also operates a consignment business that makes use of its proprietary intravenous solution technologies. The company is taking on the challenge of developing global markets, especially in Asia. With the aim of being the best partner for people worldwide in the field of clinical nutrition, the company constantly seeks to take on new challenges. Otsuka Pharmaceutical Factory will continue to deliver a stable supply of safe, high-quality products to patients and healthcare professionals.

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