Good health starts in the gut

Consumers are discovering that a healthy gut is much more than good digestion. The DuPont Digestive Health Platform delivers targeted solutions for the growing gut health marketIf there is one thing that health-conscious consumers are increasingly aware of, it’s that good health and wellbeing often starts in the gut. The rise in food product launches with a digestive health claim also reflects the general consumer preference for naturally functional foods and beverages to meet their nutritional needs. For food manufacturers, the gut health market represents a vast opportunity to explore. Euromonitor insights predict the global digestive health market will continue to maintain a 5.7% CAGR in retail value up to 2023 and beyond.

The biggest potential lies with products that are enriched with probiotics and fiber and are free from ingredients that can cause intolerance, such as gluten and lactose. This would allow products to align with consumers’ perceptions of what

a gut-friendly diet looks like, one that can relieve digestive discomfort, improve immune health, and support overall weight management. An increasing amount of studies also point to the connection between gut health and cognitive health as a future growth area in the market.

To take advantage of these opportunities, you need the right product development partner. That’s where DuPont Nutrition & Biosciences comes in. Our Digestive Health Platform offers the ingredient solutions, application knowhow and regulatory support you need to capture market share. The key to your success is that consumers can feel a difference. By drawing on our nutritional, scientific, regulatory and functional capabilities, that’s a promise your brand can keep.

Your Daily Challenges

• Providing real benefits for

consumer wellbeing

• Ensuring stable and appealing

tastes and textures

• Enhancing the naturally healthy

image of your brand

Benefits and gains

Your business gains Your product benefits Our proven solution

•Leveragethehealthyimageofyour

brand

• Achieve premium positioning

•Benefitfromextensivetechnicaland

regulatory support

•Reduceyourtimetomarket

•Clinicallydocumentedingredients

•Appealingtastesandtextures

•Free-fromlactose/gluten

opportunities

•Stabilitythroughoutshelflife

•Premiumprobiotics

•Startercultures

•Prebioticfibers(polydextrose,

human milk oligosaccharides)

•Functionalsystems,emulsifiers,

enzymes & hydrocolloids

Solutions overview for food and beverage applications

Digestive health food and beverage

segments

Food application Gut health

Health benefits obtained via the gut

Immune health Weight management

Probiotic fermented dairy

Yogurt,Drinking yogurt

Bifido B. lactis HN019™, documented for gut comfort

Dophilus L. acidophilus NCFM®, documented for well-being & gut comfortYO-MIX® PRO seriesSingleprobioticstrains“All in One” yogurt cultures with probiotic species

Protect Adult, B. lactis Bl-04™, documented for immune health

Probiotic fermented plant-based food and beverages

Plant-based dairy alternatives, Fermented juices, Tea etc.

Danisco® VEGE Cultures, including Dophilus

and Bifido VEGE

Other probiotic food and beverages

Bars, Beverages, Cereals

BifidoB. lactis HN019™

Dophilus L. acidophilus NCFM®

Protect Adult, B. lactis Bl-04™

Protect EarlylifeL. Rhamnosus HN001™

ShapeB. lactis B420™

Fibers/prebioticsFood, Beverages, Formula

CARE4U™ Human Milk OligosaccharidesLitesse®polydextroseDuPont™ Danisco® Nurica™ FIBRIM®SoyFiberFORTEFIBER™SolubleDietaryFiber

CARE4U™ Human Milk Oligosaccharides

Litesse®polydextrose

FORTEFIBER™ SolubleDietaryFiber

Lactose-free Dairy, FormulaDuPont™ Danisco® Bonlacta™ GODOYNL-2Lactase

Gluten-freeBakedgoods

WELLENCE™GF321,POWERFlex®GF 4201, PowerBake® GF 101, FunctionalSystems,Hydrocolloids, Enzymes,Emulsifiers,SoyProteins, Peanuggets,Litesse® polydextrose, FORTEFIBER™ SolubleDietaryFiber,XIVIA® Xylitol, Fermentates

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4-1 Nutrition & Biosciences

www.food.dupont.com

DuPont™, the DuPont Oval Logo, and all trademarks and service marks denoted with ™, SM or ® are owned by affiliates of DuPont de Nemours, Inc. unless otherwise noted. © 2019 DuPont. The information contained herein is based on data known to DuPont or its affiliates at the time of preparation of the information and believed by them to be reliable. This is business-to-business information intended for food, beverage and supplement producers, and is not intended for the final consumer of a finished food, beverage or supplement product. The information is provided “as is” and its use is at the recipient’s sole discretion and risk. It is the recipient’s sole responsibility to determine the suitability and legality of its proposed use of DuPont products for its specific purposes. Information and statements herein shall not be construed as licenses to practice, or recommendations to infringe, any patents or other intellectual property rights of DuPont or others. DUPONT HEREBY EXPRESSLY DISCLAIMS (I) ANY AND ALL LIABILITY IN CONNECTION WITH SUCH INFORMATION, INCLUDING, BUT NOT LIMITED TO, ANY LIABILITY RELATING TO THE ACCURACY, COMPLETENESS, OR USEFULNESS OF SUCH INFORMATION, AND (II) ANY AND ALL REPRESENTATIONS OR WARRANTIES, EXPRESS OR IMPLIED, WITH RESPECT TO SUCH INFORMATION, OR ANY PART THEREOF, INCLUDING ALL REPRESENTATIONS AND WARRANTIES OF TITLE, NONINFRINGEMENT OF COPYRIGHT OR PATENT RIGHTS OF OTHERS, MERCHANTABILITY, FITNESS OR SUITABILITY FOR ANY PURPOSE, AND WARRANTIES ARISING BY LAW, STATUTE, USAGE OF TRADE OR COURSE OF DEALING.

Application supportAll our solutions for digestive health have been developed and tested in the DuPont application centers. This, together with our extensive global presence and knowledge of food products, processes and regulations, make us a strong partner for your product development needs.

is a line of clinically mastered probiotic solutions from the leading industry experts at DuPontHOWARU® premium probiotics are offered as single strains or pre-formulated blends, all validated by gold-standard clinical trials. Each robust strain or strain-combination provides an array of benefits sure to meet your manufacturing needs and that of your unique customer.

The Human Microbiome VentureThe human microbiome comprises all the microbes that live in and on the body. In fact, there are more microbes living in the human as there are cells in the human body. These microbes produce thousands of different metabolites and are responsible for as much as 30% of the metabolites found in human blood. Academic research over the past 10 years or so has demonstrated the significant role the microbiome plays in human health and disease.

To spearhead the development of new microbiome science-based solutions, DuPont Nutrition & Biosciences has establishedtheHumanMicrobiomeVenture(HMV).ThisteamwillcomplementandbuildupontheexistingleadershipofDuPontintheareasofprobioticsandprebiotics,includinghumanmilkoligosaccharides(HMOs),todelivernovel intervention options that can modulate the microbiome and exert a beneficial or even a therapeutic effect. The HMV team is also engaging in strategic partnerships with other microbiome leaders in academia and in the healthcare industry to accelerate product development and future commercialization of these products.

THE MICROBIOME BY NUMBERS:

Tens Of TrillionsOf Microbial Cells

A Complex Microbial Ecosystem>1000 Species

Millions Of Microbial Genes

Producing Over 500,000Different Metabolites

30% Of The Metabolites Found In Your Blood Are

Coming From The Microbiome

The Scientific Community Has Been Studying

The Microbiome For over 20 Years