GMFs Final Presentation

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    Genetically Modified FooTolulope Awolusi, Alicia Brown, Jamesa Hogges, Brittny Thoma

    ENVH 7234 Term ro!ect resentation"all 2#$4

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    Outline

    I. IntroductionII.Exposure scenarios and adverse healt

    effects associated with GMOsIII.PH ImplicationsIV.Grant ProposalV. ummary

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    !hat are GMOs"GMFs#

    $hrou%h the use ofrecom&inant '()technolo%y* or%anisms+%enetic material can &ealtered and transferred from

    one or%anism to another,chep-er* /01. $hisprocess yields %eneticallymodified or%anisms ,GMOs1.

    http://mediad.publicbroadcasting.net/p/nhpr/files/201211/EarthTalkPro

    osition37alifornia.!P"

    0234 5ecom&inant

    027/4 First GMO Pa

    0274 F') )pproved

    o Humulin

    02284 GMO Introdu

    6ommercial Mar-et

    o 9Flavr avr: tom

    02224 GMOs )dopte

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    !hy are GMFs made#

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    How GMFs are made#

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    6urrent ; Potential

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    Humans

    Allergenicity Immune system falsely identifies allergens as a xenobiotic and induce allergic re Foreign genes in GM crops may create a new allergen or cause an allergic respons

    susceptible individuals.o Ex: the decrease in glutelin levels in rice has been associated with an incre

    levels prolamins.

    wo main areas of concern is

    antibiotic resistance

    and al

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    Humans

    wo main areas of concern is

    antibiotic resistance

    and al

    Antibiotic !esistance" Antibiotics are gradually losing their medical effectivenessdue to the increas

    of diseases that are becoming resistant

    " If bacteria carrying antibiotic resistance genes were to cause an infection# it wo

    very difficultfor doctors to treat using traditional antibiotics.

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    ?a&elin%

    = (ot reDuired in the

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    t cotton ,Bacillusthuringiensis1o economic %rowth*

    employment* povertyreduction

    o decreased use ofpesticides

    = Golden rice Vitamin ) dvisual pr

    other dis 'isadvanta%

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    5e%ulations ; 6ontrovers

    5e%ulations= 6aseC&yCcase approach

    to ris- assessment,F')" EP)1

    = )uthoriation permit forenvironmental release ofGMOs ,)PHI1

    = ?a&ellin% ,(ot to &eimposedCF')"

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    Pu&lic Health Implication

    Pu&lic )wareness)ccordin% to a survey conducted &y $he Food Policy Institute ,FPI1awareness of GM food consumption is currently low in the

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    Pu&lic Health Implication

    How do we avoid GMOs# >uy or%anic products >uy products that are la&eled

    nonCGMO )void atCris- in%redients >uy products listed on a nonC

    GMO hoppin% Guide

    Visit4www. (onGMOhoppin%Guide.com

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    Grant Proposal Title of the Proposed Project:Genetically Modified Foods

    Potential Funding Source:

    o (ational Institute of Health ,(IH1o Food ; 'ru% )dministration ,F')1o

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    Grant Proposal 6ontinued

    Specific Aims: $hrou%hout this proect* studies will &e conducted on determine whether GMOs exposure adversely affects human health.

    Significance:!e anticipate that this proect would &e si%nificant due

    to uncover the &enefits and disadvanta%es revealed in current research a

    what remains un-nown. GMOs can &e viewed positively &ecause they ca

    eliminate food insecurity &ut they can also &e viewed ne%atively &ecause

    potential harm they may cause re%ardin% &iodiversity and livin% or%anis

    proposal with help to raise awareness to the field of pu&lic health &ecau

    usa%e is increasin% and the field of research is constantly pro%ressin%.

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    Grant Proposal 6ontinued

    = Approach

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    Sustaina#ility Measures:)lthou%h the proect is set for a tenCyear study* we

    continue this research for lon%er if possi&le.

    o !hy#

    increase -nowled%e of potential health effects from lon% term exposu

    to evaluate new trans%enic %enes that may &e developed in the future

    it is possi&le that more %rants will have to &e applied for

    %ettin% consumers* trade associations* and possi&ly policyma-ers inv

    %enerate money for this research

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    Grant Proposal 6ontinued $!aluation Plan

    Evaluations would &e %iven &iannually to monitor the pro%ress of the propose

    well as su&ect participation Budget & ustification !lan

    Items Annual

    Cost

    Total Cost

    (10 years)

    Laboratory

    Testing

    $%''' $%&'#'''

    Researchers () $%'(#''' $%#'('#''

    '

    !ub"ect

    Incentives

    $''' $&'#'''

    #ood$

    %& crops

    'rganic

    $)(#*''

    $%&*#*('

    $)(*#'''

    $%#&**#('

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    5eferences )min* ?.* )&ul* B.* Gausmian* M. H.* ul-ifi* F. ,/081. 'eterminants of pu&lic attitude to %enetica

    [email protected] %ne &,01.

    )n%eli-e* H.* Matthias* M.* or%* 5.* tephan* .* Hanchan* $.* ; >eatrix* $. ,/001. Environmenta%enetically modified plantsC concepts and controversies.En'ironmental (ciences Europe, 23,001.

    >oyce* . ).* )ssaad* ).* >ur-s* ). !.* ones* . M.* ampson* H. ).* !ood* 5. ).* . . . chwanin%er* . Guidelines for the 'ia%nosis and Mana%ement of Food )ller%y in the .* Gil&ertson* ?. ).* tau&* . M.* >annon* G. ).* Goodman* 5. E.* ... ; ilvanHuman safety and %enetically modified plants4 a review of anti&iotic resistance mar-ers and future traselection technolo%ies.Journal o) Applie* /icro0iology* &&,01* 3CA.

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    5eferences 6ontinued a-u&* B. ,//21. Genetically modified a&ominations4 widespread opposition to GMOs mi%ht have

    causes.European /olecular Biology %rgani1ation, $#,001.

    Ma%aLaCGme* .* ; 6aldern de la >arca* ). ,//21. 5is- assessment of %enetically modified crops fhealth.Nutrition e'iews* 7,01* 0C0@.

    Marmiroli* (.* Maestri* E.* GullN* M.* Malcevschi* ).* Peano* 6.* >ordoni* 5.* ; 'e >ellis* G. ,//71. Meof GMOs in food and feed. )nalytical ; >ioanalytical 6hemistry* A2,A1* A@2CA78. doi40/.0//3"s//0@

    Morisset* '.* (ova-* P.* upanic* '.* Gruden* B.* ?avrac* (.* ; el* . ,/01. GMOsee-4 a user friendlyGMO testin%.B/+ Bioin)ormatics* 0J* 0C0A.

    Pamela* 5. ,/001. Plants* %enetics* sustaina&le a%riculture and %lo&al food security. Genetic ociety of0/.0JA8" %enetics.000. 07JJA.

    aim* M. ,/0/1. >enefits of %enetically modified crops for the poor4 household income* nutrition* andBiotechnology* 27,J1* JJCJJ3. doi40/.0/0@".n&t./0/./3.//2

    chep-er* B. ,/01. GMO $ruths* 6onseDuences* and the 5i%ht to Bnow. Holistic rimary +are* $3,8 in%h* O.* Ghai* .* Paul* '.* ; ain* 5. ,//@1. Genetically modified crops4 uccess* safety assessment

    Appl /icro0iol Biotechnol,7$* J27C@/3. $heresa* P.* ; Phillips* $. ,//71. Genetically modified or%anisms ,GMOs14 $rans%enic 6rops and

    Nature E*ucation* $,0140A. Valeria* . ,//@1. $he ethical dilemma of %enetically modified foods. The Journal o) En'ironmental H Vinceno* P.* oanna* P.* 5iccardo* G. ,/001. From ris- assessment to inCcontext traectory evaluation

    social implications.En'ironmental (ciences Europe, 23,A1.

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    uestions#