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Global Measles and Rubella Update November 2018

Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

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Page 1: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Global Measles and Rubella UpdateNovember 2018

Page 2: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles

Page 3: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Number of Reported Measles Cases by WHO Regions

2018

RegionMember States*

Suspected cases

Measles cases

Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov DecDate

Received

AFR 42/47 44749 25494 12955 6897 5642 2998 4295 5058 3533 2547 1543 1564 1121 1399 1436 0 0 2018-11

AMR 32/35 24627 10342 0 0 10342 3 16 84 152 291 216 410 138 779 8253 0 0 2018-11

EMR 20/21 35676 19384 3975 6812 8597 2234 1744 2660 2710 3129 2245 2403 1157 996 106 0 0 2018-11

EUR 53/53 63873 54354 30579 2008 21767 5647 6589 7376 7658 8703 7037 5307 3611 2411 15 0 0 2018-11

SEAR 11/11 80556 61273 49884 8828 2561 7787 7600 12074 10789 10079 4786 2849 2983 2099 227 0 0 2018-11

WPR 26/27 52221 18545 10757 483 7305 1921 2478 3386 3232 2941 2098 1348 550 540 51 0 0 2018-11

Total 184/194 301702 189392 108150 25028 56214 20590 22722 30638 28074 27690 17925 13881 9560 8224 10088 0 0

2017

RegionMember States*

Suspected cases

Measles cases

Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov DecDate

Received

AFR 43/47 51565 24838 11007 8845 4986 3216 2896 3648 2370 2026 1859 1475 1412 1519 1695 1315 1407 2018-11

AMR 31/35 10886 895 0 0 895 1 8 19 13 5 0 0 1 1 0 0 847 2018-11

EMR 20/21 36139 12777 1918 693 10166 1103 1080 1296 1280 1460 1057 1061 812 706 941 950 1031 2018-11

EUR 53/53 31134 24592 4427 6059 14106 1422 1873 3004 2885 2921 2572 1380 868 965 1327 2352 3023 2018-11

SEAR 11/11 99722 79368 56164 17492 5712 8572 9758 13139 10343 7564 4627 3888 4412 3846 3167 5011 5041 2018-11

WPR 26/27 53130 10296 2692 107 7497 778 894 1501 1222 1120 800 772 700 725 770 617 397 2018-11

Total 184/194 282576 152766 76208 33196 43362 15092 16509 22607 18113 15096 10915 8576 8205 7762 7900 10245 11746

Notes: Based on data received 2018-11 - This is surveillance data, hence for the last month, the data may be incomplete. * Member States

Reporting / Total Member States in Region

Page 4: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

2018

RegionMember States*

Suspected cases

Measles cases

Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov DecDate

Received

AFR 42/47 44749 25494 12955 6897 5642 2998 4295 5058 3533 2547 1543 1564 1121 1399 1436 0 0 2018-11

AMR 32/35 24627 10342 0 0 10342 3 16 84 152 291 216 410 138 779 8253 0 0 2018-11

EMR 20/21 35676 19384 3975 6812 8597 2234 1744 2660 2710 3129 2245 2403 1157 996 106 0 0 2018-11

EUR 53/53 63873 54354 30579 2008 21767 5647 6589 7376 7658 8703 7037 5307 3611 2411 15 0 0 2018-11

SEAR 11/11 80556 61273 49884 8828 2561 7787 7600 12074 10789 10079 4786 2849 2983 2099 227 0 0 2018-11

WPR 26/27 52221 18545 10757 483 7305 1921 2478 3386 3232 2941 2098 1348 550 540 51 0 0 2018-11

Total 184/194 301702 189392 108150 25028 56214 20590 22722 30638 28074 27690 17925 13881 9560 8224 10088 0 0

Number of Reported Measles Cases by WHO Regions

Notes: Based on data received 2018-11 and 2017-11 - This is surveillance data, hence for the last month, the data may be incomplete. *

Member States Reporting / Total Member States in Region

2017

RegionMember States*

Suspected cases

Measles cases

Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov DecDate

Received

AFR 43/47 38479 17856 8587 5248 4021 3037 2674 3228 1893 1704 1383 929 1021 1173 814 0 0 2017-11

AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11

EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899 730 460 234 22 0 0 2017-11

EUR 52/53 17256 13713 2499 3485 7729 1092 1850 2919 1708 1869 1492 1281 807 691 4 0 0 2017-11

SEAR 11/11 71098 55940 42574 8200 5166 7344 8621 12151 9474 6884 3849 2803 3165 1506 143 0 0 2017-11

WPR 26/27 37444 8657 2533 74 6050 639 823 1461 1295 1174 846 784 803 832 0 0 0 2017-11

Total 182/194 199868 104975 56403 17672 30900 13206 14894 20747 15967 13312 8470 6530 6285 4460 1104 0 0

Page 5: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles case distribution by month and WHO Region (2014-2018)

20

14

-01

20

14

-02

20

14

-03

20

14

-04

20

14

-05

20

14

-06

20

14

-07

20

14

-08

20

14

-09

20

14

-10

20

14

-11

20

14

-12

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

0

5000

10000

15000

20000

25000

30000

35000

40000

Month of onset

Mea

sles

cas

es

(Lab

+Ep

i+C

linic

al)

WPRSEAREUREMRAMRAFR

Notes: Based on data received 2018-11 - Data Source: IVB Database - This is surveillance data, hence for the last month(s), the data may be

incomplete.

The clustering of cases in AMR at specific time points is an artifact of reporting

Page 6: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles Incidence Rate per Million(12M period)

Top 10**

Country Cases Rate

India 66794 50.44

Ukraine 34218 770.01

Philippines 12243 118.50

Yemen 9499 344.36

Nigeria 7299 39.24

Serbia 5725 649.09

China 4200 2.99

Pakistan 3721 19.26

DR Congo 3672 46.64

Indonesia 3476 13.31

Other countries with

high incidence rates***

Country Cases Rate

Albania 1396 477.05

Liberia 1902 412.24

Georgia 1471 374.74

Montenegro 203 322.93

Greece 3032 271.11

Lebanon 907 151.00

Notes: Based on data received 2018-11 and covering the period between 2017-10 and 2018-09 - Incidence: Number of cases / population* *

100,000 - * World population prospects, 2017 revision - ** Countries with the highest number of cases for the period - *** Countries with the

highest incidence rates (excluding those already listed in the table above)

Measles cases from countries with known discrepancies between case-based and aggregate surveillance, as reported by country

Country Year Cases Data Source

DR Congo 2017 45165 SITUATION EPIDEMIOLOGIQUE DE LA ROUGEOLE EN RDC, Week of 6/11/20182018 39496

Somalia 2017 23394 Somali EPI/POL Weekly Update Week 43

2018 8097

Page 7: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Disclaimer

This document contains data provided to WHO by member states. Note that some member states only

provide aggregate data to WHO, and for these, we are unable to generate a country profile. Some

member states report all cases at one time point for the entire year, and thus epidemiologic curves

generated are not accurate and a reporting artifact. For some countries, cases are reported by age

category, not by exact age in months and/or years. Thus, age distribution/incidence is approximate.

Cases classified as pending by countries are classified at WHO as clinically compatible at this time, and

thus numbers might different between data shown here and provided by the member state or WHO

country/regional offices.

*UN population data is used as the denominator for calculating incidence.

Page 8: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles case distribution (AFR), 2014-2018

20

14

-01

20

14

-02

20

14

-03

20

14

-04

20

14

-05

20

14

-06

20

14

-07

20

14

-08

20

14

-09

20

14

-10

20

14

-11

20

14

-12

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

0

2000

4000

6000

8000

Month of onset

Nu

mb

er o

f m

eas

les

case

s

Uganda

OthersNigeriaNiger

LiberiaGabon

EthiopiaEquatorial GuineaDR Congo

CameroonAngola

Notes: Based on data received 2018-11 - Data Source: IVB Database

DRC has experienced a nationwide epidemic that has affected all Provinces, however, only a small proportion of the measles cases in the IDSR

aggregate reporting system are reflected in the case based data. As of 27 May 2013, South Sudan has reassigned to the Africa region (AFR)

from the Eastern Mediterranean region (EMR). For data presentation and statistical purposes, South Sudan data is presented in AFR for all the

years.

Page 9: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles cases: Chad

0

100

200

300

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

Sub-national (9-59 M)

Cov: 112.4%Sub-national (9-59 M)

National SIA Sub-national SIA

0

50

100

150

200

250

300

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Chad age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

50

100

150

Inci

den

ce r

ate

per

1,0

00

,00

0

111.8132.1

69.154.7

39.8 31.810.4

YearConfirmed

Cases

2006 15

2007 65

2008 70

2009 632

2010 219

2011 156

2012 153

2013 217

2014 1251

2015 418

2016 168

2017 26

2018 814

Page 10: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles cases: Democratic Republic of the Congo

0

1000

2000

3000

40002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

Sub-national (6-59 M)

Cov: 103.5%

National SIA Sub-national SIA

0

500

1000

1500

2000

2500

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Democratic Republic of the Congo age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

50

100

150

200

Inci

den

ce r

ate

per

1,0

00

,00

0

151.7

188.8

69

13.4 4.6 2.4 0.4

YearConfirmed

Cases

2006 1012

2007 539

2008 214

2009 83

2010 208

2011 1651

2012 2332

2013 2527

2014 1649

2015 5029

2016 4932

2017 3621

2018 3445

Page 11: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles cases: Ethiopia

0

200

400

600

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

Sub-national (9 M-14 Y)

Cov: 96.3%

Sub-national (6-179 M)

Cov: 98%

National SIA Sub-national SIA

0

100

200

300

400

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Ethiopia age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

10

20

Inci

den

ce r

ate

per

1,0

00

,00

0

23.1 24.5

17

11.9

17.9

6.1

0.5

YearConfirmed

Cases

2006 1278

2007 1472

2008 3161

2009 2642

2010 6205

2011 3552

2012 4616

2013 6137

2014 14282

2015 17778

2016 4568

2017 1912

2018 967

Page 12: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles cases: Kenya

0

50

100

1502

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

20

40

60

80

100

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Kenya age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

10

20

Inci

den

ce r

ate

per

1,0

00

,00

0

17.4

14.1

6.6

3 3.81.8

0.6

YearConfirmed

Cases

2006 2350

2007 486

2008 34

2009 65

2010 105

2011 2462

2012 2380

2013 243

2014 390

2015 112

2016 124

2017 63

2018 374

Page 13: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles cases: Madagascar

0

200

400

600

800

10002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

10

20

30

40

50

60

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Madagascar age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

10

20

Inci

den

ce r

ate

per

1,0

00

,00

0

18.7

14.516.5

12.3

3.42.1

0.7

YearConfirmed

Cases

2006 2

2007 0

2008 12

2009 2

2010 1

2011 1

2012 3

2013 7

2014 1

2015 6

2016 17

2017 84

2018 974

Page 14: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles cases: Nigeria

0

1000

2000

30002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

Sub-national (6 M-10 Y) NA (9-59 M)

National SIA Sub-national SIA

0

2000

4000

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Nigeria age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

50

100

150

Inci

den

ce r

ate

per

1,0

00

,00

0

123.7

149.7

65.7

247.9 5.2 2.3

YearConfirmed

Cases

2006 1019

2007 3129

2008 10453

2009 1498

2010 9072

2011 19062

2012 6423

2013 55392

2014 6850

2015 12391

2016 17581

2017 11188

2018 6404

Page 15: Global Measles and Rubella Update November 2018 - WHO...AMR 30/35 8658 224 0 0 224 1 8 19 13 5 1 3 29 24 121 0 0 2017-11 EMR 20/21 26933 8585 210 665 7710 1093 918 969 1584 1676 899

Measles cases: Uganda

0

100

200

300

400

500

6002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

500

1000

1500

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Uganda age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

50

100

150

200

250

Inci

den

ce r

ate

per

1,0

00

,00

0

224.4 220.5

106.5

51.817.9 4.5 1.9

YearConfirmed

Cases

2006 1035

2007 291

2008 115

2009 86

2010 41

2011 132

2012 720

2013 460

2014 315

2015 466

2016 252

2017 892

2018 2311

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Measles case distribution (AMR), 2014-2018

20

14

-01

20

14

-02

20

14

-03

20

14

-04

20

14

-05

20

14

-06

20

14

-07

20

14

-08

20

14

-09

20

14

-10

20

14

-11

20

14

-12

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

0

500

1000

1500

2000

2500

3000

3500

4000

4500

5000

5500

6000

6500

7000

7500

8000

8500

9000

Month of onset

Nu

mb

er o

f m

eas

les

case

s

Venezuela (Bolivarian Republic of)

USAPeruOthersMexicoEcuador

ColombiaChileCanadaBrazilArgentina

Notes: Based on data received 2018-11 - Data Source: IVB Database

The clustering of cases at specific time points is an artifact of reporting

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Measles cases: Brazil

0

2000

4000

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

YearConfirmed

Cases

2008 0

2009 0

2010 68

2012 2

2013 192

2014 708

2015 214

2016 0

2017 0

2018 4299

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Measles cases: Venezuela (Bolivarian Republic of)

0

2000

4000

60002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

500

1000

1500

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Venezuela (Bolivarian Republic of) age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

500

1000

1500

Inci

den

ce r

ate

per

1,0

00

,00

0

1541.4

546

150.5 106.6 29.9 11.8 5.5

YearConfirmed

Cases

2008 0

2009 0

2010 0

2011 0

2012 1

2013 0

2014 0

2015 0

2016 0

2017 727

2018 5525

The clustering of cases at specific time points is an artifact of reporting

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Measles case distribution (EMR), 2014-2018

20

14

-01

20

14

-02

20

14

-03

20

14

-04

20

14

-05

20

14

-06

20

14

-07

20

14

-08

20

14

-09

20

14

-10

20

14

-11

20

14

-12

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

0

500

1000

1500

2000

2500

3000

Month of onset

Nu

mb

er o

f m

eas

les

case

s

YemenUnited Arab EmiratesSyrian Arab Republic

SudanSomaliaSaudi Arabia

PakistanOthersIraqEgyptAfghanistan

Notes: Based on data received 2018-11 - Data Source: IVB Database

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Measles cases: Libya

0

100

200

300

4002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

50

100

150

200

250

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Libya age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

500

1000

1500

Inci

den

ce r

ate

per

1,0

00

,00

0

1455.6

390.4

115.5 76.6 32 33.6 14.5

YearConfirmed

Cases

2006 38

2007 59

2008 8

2009 329

2010 54

2011 126

2012 325

2013 164

2014 176

2015 87

2016 28

2017 3

2018 622

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Measles cases: Sudan

0

200

400

600

800

10002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

500

1000

1500

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Sudan age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

100

200

300

400

500

Inci

den

ce r

ate

per

1,0

00

,00

0

454.4

270.6

71.232.8 38.4 31.7 4.9

YearConfirmed

Cases

2006 274

2007 483

2008 97

2009 68

2010 613

2011 5616

2012 8521

2013 2811

2014 676

2015 3585

2016 1767

2017 665

2018 2929

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Measles cases: Pakistan

0

500

1000

1500

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

500

1000

1500

2000

2500

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Pakistan age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

50

100

150

Inci

den

ce r

ate

per

1,0

00

,00

0

157.6

105.9

27.55.2 0.8 0.4 0

YearConfirmed

Cases

2006 35

2007 33

2008 53

2009 472

2010 1111

2011 2676

2012 8048

2013 8030

2014 1370

2015 1117

2016 2806

2017 6780

2018 2358

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Measles cases: Yemen

0

500

1000

1500

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

2000

4000

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Yemen age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

500

1000

1500

2000

Inci

den

ce r

ate

per

1,0

00

,00

0

1916.4

1525.7

611.7

143.4 36.1 45.9 8.1

YearConfirmed

Cases

2006 4989

2007 50

2008 53

2009 127

2010 372

2011 847

2012 2143

2013 571

2014 817

2015 465

2016 143

2017 2101

2018 8742

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Measles case distribution (EUR), 2014-2018

20

14

-01

20

14

-02

20

14

-03

20

14

-04

20

14

-05

20

14

-06

20

14

-07

20

14

-08

20

14

-09

20

14

-10

20

14

-11

20

14

-12

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

0

1000

2000

3000

4000

5000

6000

7000

8000

9000

Month of onset

Nu

mb

er o

f m

eas

les

case

s

UkraineSerbiaRussian FederationRomaniaOthersKyrgyzstan

ItalyGermanyGeorgia

FranceBosnia and Herzegovina

Notes: Based on data received 2018-11 - Data Source: IVB Database

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Measles cases: Israel

0

100

2002

01

6-1

1

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

50

100

150

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Israel age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

100

200

300

400

Inci

den

ce r

ate

per

1,0

00

,00

0

378.8

226.9166.1

65.532.6 29.9 18.9

YearConfirmed

Cases

2006 8

2007 539

2008 891

2009 5

2010 19

2011 46

2012 149

2013 57

2014 3

2015 80

2016 10

2017 16

2018 526

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Measles cases: Ukraine

0

2000

4000

60002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

2000

4000

6000

8000

<1 year 1-4 years 5-9 years 10-14 years 15-19 years 20-29 years 30+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Ukraine age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

1000

2000

3000

4000

Inci

den

ce r

ate

per

1,0

00

,00

0

3981.3

2950.6 2768.52239.1

773.3 543.4272.9

YearConfirmed

Cases

2006 945

2007 232

2008 41

2009 24

2010 42

2011 1313

2012 12744

2013 3308

2014 2326

2015 141

2016 90

2017 4782

2018 31312

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Measles case distribution (SEAR (excl. India)), 2014-2018

20

14

-01

20

14

-02

20

14

-03

20

14

-04

20

14

-05

20

14

-06

20

14

-07

20

14

-08

20

14

-09

20

14

-10

20

14

-11

20

14

-12

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

0

500

1000

1500

2000

2500

3000

3500

Month of onset

Nu

mb

er o

f m

eas

les

case

s

Timor-LesteThailandSri LankaNepalMyanmar

MaldivesIndonesiaDPR KoreaBhutanBangladesh

Notes: Based on data received 2018-11 - Data Source: IVB Database

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Measles cases: Indonesia

0

2000

4000

60002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

Sub-national (9 M-15 Y)

Cov: 100.5%

National SIA Sub-national SIA

0

100

200

300

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Indonesia age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

10

20

Inci

den

ce r

ate

per

1,0

00

,00

0

17.915.1

13.8

9

4.5

0.9 0.2

YearConfirmed

Cases

2006 21911

2007 20837

2008 16417

2009 21008

2010 23471

2011 23510

2012 16786

2013 10093

2014 9498

2015 6209

2016 7204

2017 11389

2018 2374

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Measles case distribution (SEAR, India), 2014-2018

20

14

-01

20

14

-02

20

14

-03

20

14

-04

20

14

-05

20

14

-06

20

14

-07

20

14

-08

20

14

-09

20

14

-10

20

14

-11

20

14

-12

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

0

5000

10000

15000

Month of onset

Nu

mb

er o

f m

eas

les

case

s

India

Notes: Based on data received 2018-11 - Data Source: IVB Database

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Measles cases: India

0

10000

20000

300002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

Rollover-Nat (9 M-15 Y)

National SIA Sub-national SIA

0

2000

4000

6000

8000

10000

12000

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

India age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

20

40

60

80

100

Inci

den

ce r

ate

per

1,0

00

,00

0

98.391.5

77.5

21.5

4.5 1.4 0.2

YearConfirmed

Cases

2014 80306

2015 83026

2016 70798

2017 60468

2018 55399

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Measles cases: Thailand

0

100

200

300

4002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

DiscardedClinicalEpi

Lab Month of onset

Nu

mb

er o

f ca

ses

0

100

200

300

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Thailand age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

50

100

150

200

250

Inci

den

ce r

ate

per

1,0

00

,00

0

209.2

77.6

27.5 14.8 25.9 20.70.8

YearConfirmed

Cases

2006 3962

2007 3517

2008 6339

2009 5272

2010 2273

2011 2873

2012 4072

2013 2056

2014 834

2015 190

2016 1009

2017 2032

2018 960

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Measles case distribution (WPR), 2014-2018

20

14

-01

20

14

-02

20

14

-03

20

14

-04

20

14

-05

20

14

-06

20

14

-07

20

14

-08

20

14

-09

20

14

-10

20

14

-11

20

14

-12

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

0

2000

4000

6000

8000

10000

12000

14000

16000

18000

20000

22000

Month of onset

Nu

mb

er o

f m

eas

les

case

s

Viet NamSingaporeRepublic of KoreaPhilippinesPapua New Guinea

Others

MongoliaMalaysiaJapan

ChinaAustralia

Notes: Based on data received 2018-11 - Data Source: IVB Database

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Distribution of measles genotypes(last 12 months)

Notes: Data Source: MeaNS database (Genotypes) and IVB Database (Incidence) as of 2018-11-08 and covering the period 2017-10-01 to

2018-09-30 - Pie charts proportional to the number of sequenced viruses

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Rubella

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Number of Reported Rubella Cases by WHO Regions

2018

RegionMember States*

Rubella cases

Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov DecDate

Received

AFR 42/47 2774 0 0 2774 337 362 562 357 352 253 236 196 101 18 0 0 2018-11

AMR 26/35 2 0 0 2 0 1 0 1 0 0 0 0 0 0 0 0 2018-11

EMR 20/21 928 111 48 769 104 116 160 128 131 92 111 75 10 1 0 0 2018-11

EUR 36/53 704 620 6 78 82 96 75 96 92 78 63 76 46 0 0 0 2018-11

SEAR 11/11 2245 0 557 1688 297 411 543 332 342 147 49 74 34 16 0 0 2018-11

WPR 15/27 2846 159 47 2640 113 104 290 507 750 337 252 226 266 1 0 0 2018-11

Total 150/194 9499 890 658 7951 933 1090 1630 1421 1667 907 711 647 457 36 0 0

2017

RegionMember States*

Rubella cases

Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov DecDate

Received

AFR 42/47 4569 0 0 4569 278 515 586 328 343 372 212 331 388 647 459 110 2018-11

AMR 26/35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2018-11

EMR 20/21 914 43 1 870 76 111 121 106 156 112 49 22 25 50 47 39 2018-11

EUR 30/53 703 570 17 116 59 60 87 69 85 58 54 47 38 54 46 46 2018-11

SEAR 11/11 7570 0 2080 5490 614 1092 1519 1132 810 361 329 511 345 367 256 234 2018-11

WPR 14/27 2287 258 162 1867 154 201 342 307 295 194 195 128 115 81 110 165 2018-11

Total 143/194 16043 871 2260 12912 1181 1979 2655 1942 1689 1097 839 1039 911 1199 918 594

Notes: Based on data received 2018-11 - This is surveillance data, hence for the last month, the data may be incomplete. * Member States

Reporting / Total Member States in Region

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Rubella Case Distribution by Month and WHO Region (2015-2018)

20

15

-01

20

15

-02

20

15

-03

20

15

-04

20

15

-05

20

15

-06

20

15

-07

20

15

-08

20

15

-09

20

15

-10

20

15

-11

20

15

-12

20

16

-01

20

16

-02

20

16

-03

20

16

-04

20

16

-05

20

16

-06

20

16

-07

20

16

-08

20

16

-09

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

0

500

1000

1500

2000

2500

3000

3500

4000

4500

5000

5500

Month of onset

Ru

bel

la c

ases

(La

b+E

pi+

Clin

ical

)

WPRSEAREUREMRAMRAFR

Notes: Based on data received 2018-11 - Data Source: IVB Database - This is surveillance data, hence for the last month(s), the

data may be incomplete.

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Rubella cases: AFR

0

200

400

6002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

Not introduced in EPIIntroduced <5 years ago (after 2012)

Introduced >=5 years ago (2012 and before)

Month of onset

Nu

mb

er

of

case

s(I

gM+

on

ly)

AFR Rubella Case Distribution (November 2016-October 2018)

0

200

400

600

0 1 2 3 4 5 6 7 8 91

01

11

21

31

41

51

61

71

81

92

02

12

22

32

42

52

62

72

82

93

03

13

23

33

43

53

63

73

83

94

04

14

24

34

44

54

6

Rubella vaccine not introduced before 1 January 2017 Rubella vaccine introduced before 1 January 2017

Age at onset (in years)

Nu

mb

er o

f ca

ses

(IgM

+ o

nly

)

AFR Age distribution of Rubella IgM+ cases by vaccine introduction status in the National EPI Programme (November 2017-October 2018)

Top 10 countries (last 12 M)

labelRCV in

RICases

% of Total

Ethiopia No 692 21

South Africa No 616 18

Nigeria No 454 14

Others - 386 12

DR Congo No 379 11

Uganda No 307 9

Cote d'Ivoire No 171 5

Mali No 95 3

Congo No 94 3

Mozambique No 90 3

Liberia No 59 2

Notes: Based on data received 2018-11 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31

Dec 2016.

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Rubella cases: EMR

0

50

100

1502

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

Not introduced in EPIIntroduced <5 years ago (after 2012)

Introduced >=5 years ago (2012 and before)

Month of onset

Nu

mb

er

of

case

s(l

ab +

ep

i-lin

ked

+ c

linic

al)

EMR Rubella Case Distribution (November 2016-October 2018)

0

50

100

0 1 2 3 4 5 6 7 8 91

01

11

21

31

41

51

61

71

81

92

02

12

22

32

42

52

62

72

82

93

03

13

23

33

43

53

63

73

83

94

04

14

24

34

44

54

6

Rubella vaccine not introduced before 1 January 2017 Rubella vaccine introduced before 1 January 2017

Age at onset (in years)

Nu

mb

er o

f ca

ses

(lab

+ e

pi-

linke

d +

clin

ical

) EMR Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (November 2017-October 2018)

Top 10 countries (last 12 M)

labelRCV in

RICases

% of Total

Sudan No 317 31

Yemen 2015 309 30

Pakistan No 199 20

Afghanistan No 42 4

Saudi Arabia 1991 35 3

Iran (Islamic Republic of)

2004 34 3

Others - 31 3

Tunisia 2004 20 2

United Arab Emirates

1985 10 1

Iraq 1995 9 1

Libya 1995 8 1

Notes: Based on data received 2018-11 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31

Dec 2016.

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Rubella cases: EUR

0

20

40

60

80

1002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

Not introduced in EPIIntroduced <5 years ago (after 2012)

Introduced >=5 years ago (2012 and before)

Month of onset

Nu

mb

er

of

case

s(l

ab +

ep

i-lin

ked

+ c

linic

al)

EUR Rubella Case Distribution (November 2016-October 2018)

0

100

200

0 1 2 3 4 5 6 7 8 91

01

11

21

31

41

51

61

71

81

92

02

12

22

32

42

52

62

72

82

93

03

13

23

33

43

53

63

73

83

94

04

14

24

34

44

54

6

Rubella vaccine not introduced before 1 January 2017 Rubella vaccine introduced before 1 January 2017

Age at onset (in years)

Nu

mb

er o

f ca

ses

(lab

+ e

pi-

linke

d +

clin

ical

) EUR Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (November 2017-October 2018)

Top 10 countries (last 12 M)

labelRCV in

RICases

% of Total

Poland 1988 438 55

Ukraine 2001 201 25

Germany 1991 54 7

Others - 24 3

Italy 1972 23 3

Austria 1973 18 2

Turkey 2006 12 2

Kyrgyzstan 2001 10 1

Romania 2002 6 1

Ireland 1971 5 1

Portugal 1984 5 1

Notes: Based on data received 2018-11 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31

Dec 2016. Spikes in age-distribution curve are an artifact of reporting by age bands ( 0=<1 yrs, 2=1-4 yrs, 7=5-9 yrs, 12=10-14 yrs, 17=15-19

yrs, 25=20-29 yrs, 45=30+yrs) instead of by age from some member states.

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Rubella cases: SEAR (excl. India)

0

200

400

6002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

Not introduced in EPIIntroduced <5 years ago (after 2012)

Introduced >=5 years ago (2012 and before)

Month of onset

Nu

mb

er

of

case

s(l

ab +

ep

i-lin

ked

+ c

linic

al)

SEAR (excl. India) Rubella Case Distribution (November 2016-October 2018)

0

50

100

150

0 1 2 3 4 5 6 7 8 91

01

11

21

31

41

51

61

71

81

92

02

12

22

32

42

52

62

72

82

93

03

13

23

33

43

53

63

73

83

94

04

14

24

34

44

54

6

Rubella vaccine not introduced before 1 January 2017 Rubella vaccine introduced before 1 January 2017

Age at onset (in years)

Nu

mb

er o

f ca

ses

(lab

+ e

pi-

linke

d +

clin

ical

) SEAR (excl. India) Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (November 2017-October 2018)

Top 10 countries (last 12 M)

labelRCV in

RICases

% of Total

Indonesia No 1171 77

Bangladesh 2012 291 19

Nepal 2013 34 2

Thailand 1993 11 1

Myanmar 2015 10 1

Timor-Leste 2016 5 0

Bhutan 2006 2 0

Notes: Based on data received 2018-11 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31

Dec 2016.

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Rubella cases: Bangladesh

0

20

40

602

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

ClinicalEpi

Lab

Month of onset

Nu

mb

er o

f ca

ses

SIA (9 M-<5 Y)

Cov: 101%

National SIA Sub-national SIA

0

20

40

60

80

100

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Bangladesh age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

5

10

15

20

Inci

den

ce r

ate

per

1,0

00

,00

0

19.4

6.54.3

2 1.4 0.4 0.2

YearConfirmed

Cases

2015 189

2016 165

2017 299

2018 264

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Rubella cases: India

0

200

400

600

800

10002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

ClinicalEpi

Lab

Month of onset

Nu

mb

er o

f ca

ses

SIA (9 M-15 Y)

National SIA Sub-national SIA

0

100

200

300

400

500

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

India age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

1

2

3

4

Inci

den

ce r

ate

per

1,0

00

,00

0

2.9 2.7

3.4

2.2

0.4 0.2 0

YearConfirmed

Cases

2015 3265

2016 9084

2017 2854

2018 1066

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Rubella cases: Indonesia

0

200

400

600

20

16

-10

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

ClinicalEpi

Lab

Month of onset

Nu

mb

er o

f ca

ses

SIA (9 M-15 Y)

Cov: 100.5%

National SIA Sub-national SIA

0

100

200

300

400

500

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Indonesia age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

5

10

15

20

Inci

den

ce r

ate

per

1,0

00

,00

0

13

9

19.6

15.5

5.9

20.4

YearConfirmed

Cases

2015 1379

2016 1170

2017 4349

2018 862

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Rubella cases: WPR

0

200

400

600

8002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

Not introduced in EPIIntroduced <5 years ago (after 2012)

Introduced >=5 years ago (2012 and before)

Month of onset

Nu

mb

er

of

case

s(l

ab +

ep

i-lin

ked

+ c

linic

al)

WPR Rubella Case Distribution (November 2016-October 2018)

0

50

100

0 1 2 3 4 5 6 7 8 91

01

11

21

31

41

51

61

71

81

92

02

12

22

32

42

52

62

72

82

93

03

13

23

33

43

53

63

73

83

94

04

14

24

34

44

54

6

Rubella vaccine not introduced before 1 January 2017 Rubella vaccine introduced before 1 January 2017

Age at onset (in years)

Nu

mb

er o

f ca

ses

(lab

+ e

pi-

linke

d +

clin

ical

) WPR (Excl. China) Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (November 2017-October 2018)

Top 10 countries (last 12 M)

labelRCV in

RICases

% of Total

China 2008 2800 90

Malaysia 1998 133 4

Philippines 2010 82 3

Viet Nam 2015 42 1

Japan 1989 30 1

Singapore 1990 13 0

Lao People's Democratic

Republic2012 12 0

Cambodia 2013 3 0

Republic of Korea 1982 3 0

Mongolia 2009 2 0

Others - 1 0

Notes: Based on data received 2018-11 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31

Dec 2016.

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Rubella cases: China

0

200

400

600

8002

01

6-1

0

20

16

-11

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

ClinicalEpi

Lab

Month of onset

Nu

mb

er o

f ca

ses

YearConfirmed

Cases

2014 11887

2015 8247

2016 4477

2017 1601

2018 2562

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Rubella cases: Japan

0

5

10

152

01

6-1

1

20

16

-12

20

17

-01

20

17

-02

20

17

-03

20

17

-04

20

17

-05

20

17

-06

20

17

-07

20

17

-08

20

17

-09

20

17

-10

20

17

-11

20

17

-12

20

18

-01

20

18

-02

20

18

-03

20

18

-04

20

18

-05

20

18

-06

20

18

-07

20

18

-08

20

18

-09

20

18

-10

20

18

-11

ClinicalEpi

Lab

Month of onset

Nu

mb

er o

f ca

ses

0

5

10

15

20

25

<1 year 1-4 years 5-9 years 10-14 years 15-24 years 25-39 years 40+ years

0 doses 1 dose 2+ doses Unknown

Age at onset

Nu

mb

er o

f ca

ses

Japan age distribution, vaccination status, and incidence, 2017-10 to 2018-09

0

0.5

1

Inci

den

ce r

ate

per

1,0

00

,00

0

0 0 0 0

0.2

0.9

0.1

YearConfirmed

Cases

2014 0

2015 2

2016 3

2017 5

2018 30

Japan is having a rubella outbreak but most cases are not reported to WHO

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Distribution of rubella genotypes(last 12 months)

Notes: Data Source: RubNS database (Genotypes) and IVB Database (Incidence) as of 2018-11-08 and covering the period 2017-10-01 to

2018-09-30 - Pie charts proportional to the number of sequenced viruses

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Laboratory

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Measles and Rubella IgM Data Summary

2017

RegionMember States*

Specimens received

Measles tested

Measles positive n(%)

Measles equivocal n(%)

Measles negative n(%)

Rubella tested

Rubella positive n(%)

Rubella equivocal n(%)

Rubella negative n(%)

AFR 40/47 35163 35163 4629 (13) 664 (2) 29870 (85) 29591 4962 (17) 1260 (4) 23369 (79)

AMR 27/35 7796 7449 618 (8) 46 (1) 6179 (83) 6661 308 (5) 85 (1) 5683 (85)

EMR 20/21 36251 34782 10561 (30) 127 (0) 24094 (69) 32726 1105 (3) 99 (0) 31522 (96)

EUR 38/53 42450 37192 13748 (37) 272 (1) 22642 (61) 26322 434 (2) 66 (0) 25736 (98)

SEAR 11/11 35379 32335 13177 (41) 781 (2) 20062 (62) 20383 4831 (24) 741 (4) 14804 (73)

WPR 27/27 16467 15211 2100 (14) 333 (2) 11952 (79) 12656 606 (5) 418 (3) 10748 (85)

Total 163/194 173506 162132 44833 (28) 2223 (1) 114799 (71) 128339 12246 (10) 2669 (2) 111862 (87)

2018

RegionMember States*

Specimens received

Measles tested

Measles positive n(%)

Measles equivocal n(%)

Measles negative n(%)

Rubella tested

Rubella positive n(%)

Rubella equivocal n(%)

Rubella negative n(%)

AFR 38/47 27213 27213 5376 (20) 648 (2) 21189 (78) 20507 3189 (16) 1142 (6) 16176 (79)

AMR 29/35 9356 8120 972 (12) 65 (1) 6670 (82) 6445 277 (4) 159 (2) 5630 (87)

EMR 20/21 31047 26469 9312 (35) 153 (1) 17004 (64) 23418 1198 (5) 385 (2) 21835 (93)

EUR 37/53 45831 41700 14012 (34) 241 (1) 27171 (65) 25500 584 (2) 57 (0) 24838 (97)

SEAR 11/11 22191 17899 6541 (37) 453 (3) 10895 (61) 12139 1805 (15) 361 (3) 9969 (82)

WPR 27/27 26809 20574 3643 (18) 441 (2) 10962 (53) 16244 487 (3) 319 (2) 9161 (56)

Total 162/194 162447 141975 39856 (28) 2001 (1) 93891 (66) 104253 7540 (7) 2423 (2) 87609 (84)

Notes: Based on data received 2018-11 - * Member States Reporting / Total Member States in Region

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Measles and Rubella IgM Data SummaryNotes: Based on data received 2018-11 - * Member States Reporting / Total Member States in Region

2017

RegionMember States*

Specimens received

Measles tested

Measles positive n(%)

Measles equivocal n(%)

Measles negative n(%)

Rubella tested

Rubella positive n(%)

Rubella equivocal n(%)

Rubella negative n(%)

AFR 37/47 26609 26609 3342 (13) 531 (2) 22736 (85) 22436 3562 (16) 912 (4) 17962 (80)

AMR 25/35 9646 9331 174 (2) 91 (1) 5692 (61) 8856 262 (3) 106 (1) 5523 (62)

EMR 20/21 27028 26227 7997 (30) 124 (0) 18106 (69) 24386 876 (4) 135 (1) 23375 (96)

EUR 37/53 30945 27219 11143 (41) 222 (1) 15492 (57) 18454 305 (2) 42 (0) 18042 (98)

SEAR 11/11 29452 26012 10970 (42) 553 (2) 14467 (56) 15971 3719 (23) 504 (3) 11743 (74)

WPR 27/27 12556 11686 1599 (14) 284 (2) 9792 (84) 9790 519 (5) 319 (3) 8875 (91)

Total 157/194 136236 127084 35225 (28) 1805 (1) 86285 (68) 99893 9243 (9) 2018 (2) 85520 (86)

Notes: Based on data received 2017-11 - * Member States Reporting / Total Member States in Region

2018

RegionMember States*

Specimens received

Measles tested

Measles positive n(%)

Measles equivocal n(%)

Measles negative n(%)

Rubella tested

Rubella positive n(%)

Rubella equivocal n(%)

Rubella negative n(%)

AFR 38/47 27213 27213 5376 (20) 648 (2) 21189 (78) 20507 3189 (16) 1142 (6) 16176 (79)

AMR 29/35 9356 8120 972 (12) 65 (1) 6670 (82) 6445 277 (4) 159 (2) 5630 (87)

EMR 20/21 31047 26469 9312 (35) 153 (1) 17004 (64) 23418 1198 (5) 385 (2) 21835 (93)

EUR 37/53 45831 41700 14012 (34) 241 (1) 27171 (65) 25500 584 (2) 57 (0) 24838 (97)

SEAR 11/11 22191 17899 6541 (37) 453 (3) 10895 (61) 12139 1805 (15) 361 (3) 9969 (82)

WPR 27/27 26809 20574 3643 (18) 441 (2) 10962 (53) 16244 487 (3) 319 (2) 9161 (56)

Total 162/194 162447 141975 39856 (28) 2001 (1) 93891 (66) 104253 7540 (7) 2423 (2) 87609 (84)

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Performance of Surveillance

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Surveillance sensitivity reporting rate of measles and rubella (12 months, discarded cases* per 100,000 population)

Notes: Based on data received 2018-11 and covering the period between 2017-10 and 2018-09 - Target: >= 2 discarded cases* / 100,000

population** - * Suspected cases investigated and discarded as non-measles non-rubella using laboratory testing and/or epidemiological linkage

to another etiology ** World population prospects, 2017 revision

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Supplementary Immunization Activities