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Gliwice Scientific Meetings

Twenty Years

1997-2016

Dear Friends and Colleagues,

This year we celebrate the twentieth anniversary of the Gliwice Scientific Meetings. The prehistory of this series of annual conferences includes irregular scientific meetings organized in the 60s, 70s and 80s by Prof. Mieczysław Chorąży and his team from the Department of Tumor Biology at the Institute of Oncology in Gliwice. In 1997, Prof. Joanna Rzeszowska-Wolny and her team from the newly established Department of Experimental and Clinical Radiobiology at the Institute of Oncology decided to continue this tradition of scientific meetings. From the beginning, the organizational and financial backbone for these events was provided by the Association for the Support of Cancer Research, an entity founded by researchers from the Institute of Oncology and colleagues from the Silesian University of Technology. Today the Gliwice Scientific Meetings are organized jointly by the Institute of Oncology and the Silesian University of Technology the two major scientific centers located in Gliwice. More recently, the Polish Group of the EACR also contributes to the scientific program of the conference.

The Gliwice Scientific Meetings are focused on different aspects of cancer research, molecular and cellular biology, and medicine, biotechnology and bioinformatics. During the last twenty years more than 350 lecturers from all parts of the world have contributed to the scientific excellence of our conference. The conference has hosted about 1500 participants who presented about 1000 posters. We believe that during these years the Gliwice Scientific Meeting established a solid scientific reputation, and became a recognizable event not only for Polish researchers.

On the occasion of the twentieth anniversary we would like to express our warm gratitude to all participants, co-organizers and sponsors of the conference. But the story will be continued, and hence we also invite you to future Gliwice Scientific Meetings.

Yours sincerely,

Prof. Joanna Rzeszowska-Wolny Prof. Piotr Widłak

Organizers of Gliwice Scientific Meetings:

Association for the Support of Cancer Research, Gliwice

Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch

Silesian University of Technology, Gliwice

Co-organizers and Patronage of Gliwice Scientific Meetings in years 1997-2016

Gliwice Municipal Office

Silesian Voivodship Marshal’s Office

Ministry of Science and Higher Education

Polish Academy of Sciences

European Association for Cancer Research

* * *

Mayor of Gliwice

Marshal of Silesian Voivodship

Rector of Silesian University of Technology

Director of MSC Cancer Center and Institute of Oncology, Gliwice Branch

Members of Scientific Committees of Gliwice Scientific Meetings in years 1997-2016

Peter Bannasch (Heidelberg)

Andrzej Bednarek (Łódź)

Wojciech Cholewa (Gliwice)

Mieczysław Chorąży (Gliwice)

Franck Delaunay (Nice)

Jan Filipski (Paris)

Zbigniew Grzywna (Gliwice)

Ron Hancock (Quebec)

Kari Hemminki (Heidelberg)

Jőrg Hoheisel (Heidelberg)

Roman Jaksik (Gliwice)

Barbara Jarząb (Gliwice)

Bożena Kamińska (Warszawa)

Andrzej Karbownik (Gliwice)

Marek Kimmel (Houston)

Stanisław Kochowski (Gliwice)

Witold Konopka (Warszawa)

Zdzisław Krawczyk (Gliwice)

Marek Los (Linköping)

Bogusław Maciejewski (Gliwice)

Danuta Mielżyńska (Sosnowiec)

Korneliusz Miksch (Gliwice)

Carmel Mothersill (Hamilton)

Andrzej Polański (Gliwice)

Jarosław Polański (Katowice)

Joanna Polańska (Gliwice)

Joanna Rzeszowska-Wolny (Gliwice)

Jerzy Rutkowski (Gliwice)

Martin Simard (Quebec)

Stanisław Szala (Gliwice)

Wiesław Szeja (Gliwice)

Krzysztof Szyfter (Poznań)

Dorota Ścieglinska (Gliwice)

Andrzej Świerniak (Gliwice)

Maciej Ugorski (Wrocław)

Piotr Widłak (Gliwice)

Ryszard Wilk (Gliwice)

Members of Organizing Committees of Gliwice Scientific Meetings in years 1997-2016

Alicja Bebel-Baron

Beata Bęben

Artur Cieślar-Pobuda

Iwona Domińczyk

Sylwia Drzewiecka

Agnieszka Dudło

Agnieszka Gdowicz-Kłosok

Jakub Hanus

Robert Herok

Roman Jaksik

Dorota Janicka

Magdalena Kalinowska-Herok

Izabela Kołodziejczyk

Anna Lalik

Jolanta Leonarczyk

Joanna Łanuszewska

Halina Miazgowicz

Aleksandra Miodońska

Aneta Oprzondek

Monika Pietrowska

Wojciech Pigłowski

Lucyna Ponge

Jacek Rogoliński

Joanna Rzeszowska-Wolny

Aleksandra Szczerbik

Magdalena Skonieczna

Aleksander Sochanik

Sebastian Student

Katarzyna Szołtysek

Anna Walaszczyk

Piotr Widłak

Elżbieta Zielińska-Król

1997

2016

GSM „pre-conference” in Srebrna Góra

GSM-2016, ACK Mrowisko

GSM-2016: Piotr Widłak and Joanna Rzeszowska Joanna Rzeszowska, Mieczysław Chorąży, Piotr Widłak

Scientific Programs of

Gliwice Scientific Meetings

in years 1997-2016

(I) Gliwickie Spotkania Naukowe 1997 Oddziaływania białko – DNA

21-22.11.1997

Modelowanie układów biologicznych

Bogdan Lesyng: Jak modelować układy biomolekularne; od miareczkowania do dynamiki kwantowej.

Andrzej Polański: Niesymetryczna segregacja w modelach genetyki popularnej.

Rafał Tarnawski: Modele radiobiologiczne stosowane w praktyce klinicznej.

Oddziaływania białko-DNA w procesach transkrypcji i replikacji

Ewa Bartnik: TBP - Struktura i rola w transkrypcji

Grzegorz Węgrzyn: Rola podjednostki alfa polimerazy RNA E. coli w inicjacji i antyterminacji transkrypcji.

Jolanta Zakrzewska: Oddziaływania białka DnaA z regionem inicjującym replikację

DNA.

Jarosław Marszałek: Rola nukleotydów adeninowych w oddziaływaniach białka inicjatorowego DnaA z DNA.

Jerzy Majka: Badanie oddziaływania białka DnaA z regionem inicjującym replikację DNA za pomocą techniki SPR.

Igor Konieczny: Oddziaływania białek replikacyjnych a zmiany konformacji DNA podczas inicjacji replikacji plazmidu RK2.

Dagmara Jakimowicz: Izolacja regionu oriC

za pomocą chromatografii powinowactwa.

Chromatyna i białka jądrowe

Anna Goc: Gen hydroksylazy tyrozynowej - okolica i sąsiedzi.

Eliza Wyszko: Białka specyficznie wiążące DNA i RNA.

Małgorzata Giel-Pietraszyk: Oddziaływanie peptydowych palców cynkowych z kwasami nukleinowymi.

Ewa Markiewicz: Nadekspresja białka 14-3-3 w komórkach bakteryjnych i ziemniaku.

Grzegorz Wilczyński: Technologia antysensu w badaniach fizjologicznej funkcji białek 14-3-3.

Uszkadzanie i śmierć komórek

Ewa Sikora: Mechanizmy śmierci komórek indukowanej kurkuminą (składnik curry); udział czynników transkrypcyjnych.

Krzysztof Szyfter: Ryzyko genetyczne w raku krtani określone na podstawie rozkładu genotypów baterii enzymów odpowiedzialnych za metabolizm kacerogenów.

Marcin Kruszewski: Rekombinacja homologiczna DNA w komórkach ssaków upośledzonych w naprawie uszkodzeń DNA.

Nowe techniki

Wojciech Markiewicz: Syntetyczne oligonukleotydowe biblioteki kombinatoryczne i ich zastosowanie.

Valentin Shick: Analysis of DNA and protein microchips.

(II) Gliwice Scientific Meetings 1998 Structure and Function of the Genome

50th Anniversary of Institute of Oncology in Gliwice

27-28.11.1998

Mathematical Models in Biology

Jerzy Nakielski: Tensorial model of growth and cell divisions in the root apex

Andrzej Polański: DNA statistics and the history of the population.

Andrzej Świerniak Control of aminoacids concentration in cell populations as a potential technique of cancer cell-specific therapy.

Chromatin Structure and Gene Expression

Wolfgang Henning: Histone replacement variants.

Andrzej Jerzmanowski: Chromatin structures in transcriptional regulation.

Krzysztof Staroń: Eukaryotic topoisomerase I.

Ryszard Rzepecki: Interactions of D. melanogaster karyoskeletal proteins - lamins and topoisomerase II with nucleic acids in vivo.

Wolf H. Strätling: The nuclear protein ARBP/MeCP2.

Jan Filipski: Nuclease hypersensitive sites and meiotic double-strand breaks in human DNA cloned in yeast.

Genetic Polymorphism and Cancer

Jerzy Ihnatowicz: The quantitative analysis of cancer epidemiology problems.

Barbara Jarząb: Mutations of protooncogene RET and medullary thyroid carcinoma.

Marek Rusin: Polymorphism of DNA repair genes.

Maria Wideł: Individual radiosensitivity and DNA damage.

DNA Damage, Repair and Cellular Death

Regen Drouin: UV – induced DNA damage distribution at the DNA sequence level.

Ryszard Oliński: Oxidatively damaged DNA bases - relevance to mutagenesis and cancer.

Anna Kulma: Generation of transgenic potato plans differing in carbohydrate level by manipulation of 14-3-3 protein expression.

Magdalena Milcarz: Apoptotic-like effect of 14-3-3 protein overexpression in E. coli.

Piotr Widłak: DFF, human endonuclease activated during apoptosis.

(III) Gliwickie Spotkania Naukowe 1999 Struktura i funkcje genomu

26-27.11.1999

Uszkodzenia i naprawa DNA: Mechanizmy

Małgorzata Zdzienicka: Radiowrażliwość a naprawa dwuniciowych pęknięć DNA.

Ryszard Oliński: Indukcja i reperacje oksydacyjnych uszkodzeń DNA.

Marcin Kruszewski: Liczba wywoływanych przez H2O2 uszkodzeń DNA zależy od poziomu wolnych jonów żelaza.

Wanda Baer-Dubowska: Addukty policyklicznych węglowodorów aromatycznych z DNA i ich modyfikacja przez potencjalne czynniki chemo-prewencyjne.

Barbara Tudek: Lokalizacja cyklicznych adduktów zasad DNA w obrębie ludzkiego genu p53.

Krzysztof Szyfter: Charakterystyka zmian liczby kopii DNA na poziomie chromosomowym w guzach pierwotnych i przerzutach w płaskonabłonkowym raku krtani.

Maria Grąziewicz: Fapy-adenina; wpływ oksydacyjnej pochodnej adeniny na replikację DNA i jej właściwości mutagenne.

Joanna Rzeszowska-Wolny: Białka rozpoznające uszkodzony DNA.

Dorota Butkiewicz: Polimorfizm genów NER i ryzyko zachorowania na niedrobnokomórkowego raka płuc.

Uszkodzenia i naprawa DNA: Efekty biologiczne

Marek Gniazdowski: Leki przeciwnowotworowe a czynniki transkrypcyjne.

Andrzej Pawlak: Genetyczna podatność na raka płuca i związane z nim mutacje somatyczne.

Marek Rusin: Nowe polimorfizmy genów naprawy DNA-MGMT i MPG.

Antonina Cebulska-Wasilewska: Porównanie uszkodzeń DNA i chromosomowych oraz podatność na promieniowanie UV i X w limfocytach ludzi zdrowych i pacjentów z nowotworem skóry.

Maria Wideł: Uszkodzenia DNA indukowane promieniami jonizującymi w limfocytach chorych na raka szyjki macicy i nowotwory głowy i szyi.

Ryszard Rzepecki: Regulacja aktywności topoizomerazy II i jej wiązanie do kwasów nukleinowych podczas cyklu komórkowego.

Bogdan Smołka: Metoda kometkowa; nowy sposób analizy obrazu.

Zastosowanie biologii molekularnej w medycynie

Jan Lubiński: Stan obecny i perspektywy diagnostyki molekularnej w medycynie.

Włodzimierz Krzyżosiak: Strategie wykrywania mutacji w genach.

Marek Mirowski: Zastosowanie mikroprocesorów genetycznych w diagnostyce raka tarczycy.

Janusz Limon: Znaczenie techniki FISH w diagnostyce białaczek oraz litych guzów nowotworowych człowieka.

Barbara Jarząb: Onkogen RET; znaczenie w patogenezie i diagnostyce raka tarczycy.

(IV) Gliwickie Spotkania Naukowe 2000 Współczesna terapia nowotworów: od badań molekularnych do zastosowań klinicznych

24-25.11.2000

Biologia komórek nowotworowych

Kazimierz Dux: Biologia nowotworów.

Mieczysław Chorąży: Genetyka nowotworów - udział genów w nowotworzeniu.

Jan Steffen: Dziedziczne predyspozycje do rozwoju nowotworu.

Wenancjusz Domagała: Biologia komórki nowotworowej: czym różni się komórka nowotworowa od prawidłowej?

Przemysław Janik: Angiogeneza w nowotworach.

Czesław Radzikowski: Powstawanie przerzutów.

Uszkodzenia i śmierć komórki

Józefa Wesierska-Gadek: Role of poly (ADP - ribose) polymerase-1 in the regulation of p35 response to genotoxic stimuli.

Ryszard Oliński: Analiza zawartości 8-okso-deoksyguanozyny i 8-okso-guaniny w moczu człowieka; czy ich poziom odzwierciedla aktywność enzymów reperacyjnych?

Ewa Sikora: Kurkumina jako czynnik indukujący nietypową apoptozę komórek prawidłowych i nowotworowych.

Andrzej Pawlak: Wzajemne oddziaływania niedotlenienia i ekspozycji na policykliczne węglowodory aromatyczne.

Barbara Jarząb: Analiza ekspresji genu tyreoglobuliny: zastosowanie w monitorowaniu chorych na raka tarczycy.

Genome Structure and Regulation of Gene Expression

Nicolai Sjakste: Two-directional transcription of the chicken alpha-globin gene domain.

Jean-Marc Matter: Functional interactions between bHLH transcription factors regulate neural determination in the CNS.

Wojciech Makałowski: Organizacja i ewolucja genomu człowieka.

Janusz Siedlecki: Rola 3' niekodującej części

RNA w ekspresji genów.

Piotr Widłak: Białka chromatyny rozpoznające uszkodzony DNA.

Modele matematyczne w biologii i medycynie

Marek Kimmel: Wczesna detekcja raka płuc w oparciu o tomografię komputerową i analizę biomarkerów.

Andrzej Płucienniczak: Wykorzystanie zjawiska supresji PCR, czyli patelnie w biologii molekularnej.

Krzysztof Fujarewicz: Klasyfikacja w oparciu o analizę ekspresji genów.

Andrzej Polański: Analiza stabilności bi-liniowego modelu chemioterapii nowotworów uwzględniającego fazoczułość leków.

(V) Gliwice Scientific Meetings 2001 Molecular Biology and Cancer Research

23-24.11.2001

Chromatin structure and function

Ronald Hancock: Molecular crowding and assembly of nuclear compartments.

Nocolais Sjakste: Proteasome role in pathology, first studies on proteasome gene polymorphism.

Jan Filipski: Localization of the hot spots of recombination in segments of human DNA cloned in YACs.

Jiri Fajkus: Chromatin structure of plant telomeres and subtelomeres.

Cellular stress and death

Irena Szumiel: The celluar response to DNA damage; the importance of being p35 positive.

Maciej Żylicz: Role of the heat shock proteins in cell transformation.

Ewa Nino: Oxidized low density lipoproteins in the process of atherosclerosis.

Józefa Gadek-Wesierski: Inducion of apoptosis in human cervix carcinoma cells during therapy by cisplatin.

Andrzej Pawlak: Mutations of aryl hydrocarbon responsive elements (AHRE) determine the tissue specific genotoxic consequences of PAH exposure.

Tatiana Kałuża: Real - Time PCR.

Mathematical modelling of biological processes

Marek Kimmel: SNP haplotypes and cancer.

Bogdan Lesyng: Modelling of biomolecular systems and processes using microscopic and mezoscopic approaches.

Mirosław Lachowicz: Mathematical modeling of non-local phenomena in tumor development.

Krzysztof Fujarewicz: Improved classification of microarray gene expression data using support vector machine.

Cezary Labuda: New trends in molecular diagnostics.

DNA damage and repair

Jacques Nino: Mutation strategies.

Ryszard Oliński: Oxidative stress and cancer development.

Krzysztof Szyfter: A link between chromosome instability, DNA damage and repair capacity and cancer risk factor.

Piotr Widłak: Nucleases engaged in cell death.

Marek Rusin: DNA damage recognition protein XPA – regulation of its expression and function.

Dorota Dziadkowiec: DNA repair and mating type switching in Schizosaccharomyces pombe.

(VI) Gliwice Scientific Meetings 2002

22-23.11.2002

New Trends in Cancer Therapy

Beata Utracka-Hutka: Chemotherapy - where are you going? Principles, new targets, challenges for the future.

Jan Walewski: Therapy for lymphoma: current concepts and new approaches.

Jerzy Konopa: Mechanisms of action as a basis for the development of new antitumor compounds.

Maciej Siewiński: Inhibitorotherapy of cancer.

Rafał Tarnawski: How molecular biology may improve outcome of radiation oncology interactions.

Transgenic Organisms in Agrobiotechnology and Medicine

Mieczysław Chorąży: Genetically modified organisms - introduction.

Marcin Łukaszewicz: Transgenic plants overexpressing biologically active compounds.

Agnieszka Sirko: The potential of transgenic plants for subunit vaccine production.

Jerzy Jurka: Transposable elements: horizontal transfer and mechanisms of integration.

Genomics in Medicine

Helena Sztajer: Genomics and proteomics as a tools for analysis of phospholipid hydroperoxide glutathione peroxidase expression and transformation during spermatogenesis.

Włodzimierz Krzyżosiak: Translational regulation of the BRCA1 gene.

Marek Figlerowicz: Discovery of RNAi phenomenon - turning-point in functional genomics.

Catharina Larsson: Positional cloning of tumor suppressor genes in parathyroid tumorigenesis.

Patrick Gaudray: Deciphering Menin's interaction networks as a tool to tackle its biological role.

Barbara Jarząb: Expression profiling by DNA microarray in endocrine - related cancer.

DNA Repair, Radiobiology and Medicine

Marcel Blaese: Role of cytoplasmic retinoic acid binding proteins CRABPI and II in regulating sensitivity of tumor cells to retinoids and ionizing radiation.

Kai Rothkamm: Cell-cycle-dependent contribution of non-homologous end joining and homologous recombination to the repair of radiation-induced DNA double-strand breaks in mammalian cells.

Ingo Brammer: Individual radiosensitivity: molecular mechanisms and clinical impact.

Elisabeth Ortmann: Modulation of radiation induced apoptosis by antioxidant vitamins.

Antonina Cebulska-Wasilewska: Predictive assays - comparison between various biological end-point and various doses.

Nadzeya Rabakon: Genetic efficiency of low-dose ionizing radiation in small mammals under chronic irradiation.

Barbara Tudek: Long-chain adducts of fatty acids derivatives to DNA bases, mutations and repair.

Krzysztof Szyfter: Phenotypic and genotypic indications for an impaired DNA repair capacity in laryngeal cancer subjects.

Ryszard Oliński: Oxidative DNA damage and repair; insight from determination of 8-oxoguanine and 8-oxo-2'-deoxoguanosine in extracellular fluids.

Grażyna Motykiewicz: DNA repair capacity in lymphoblasts from sisters discordant for breast cancer.

Miscellanea

Ludmila Drobot: Ruk adaptor proteins - structural and functional features.

Wiesława Widłak: Why spermatogenic cells are sensitive to elevated temperature. The role of heat shock proteins.

Dorota Rybaczek: Premature mitosis (PCC) – a preserved ability of chromatin to replicate the DNA.

Olgierd Unold: Towards DNA based computer – the initial state.

Sergey Razin: Chicken domain of alpha-globin genes: organization and regulation of globin genes expression.

(VII) Gliwice Scientific Meetings 2003

21-22.11.2003

Structure and Functions of the Genome

Sergey Razin: Domain organization of human dystrophin gene.

Jan Filipski: Mapping of the hot spots of recombination in human DNA cloned in S.cerevisiae.

Elena Youdinkova: Organization of the chicken domain of alpha-globin genes.

Vlada Philmonienko: Nuclear myosin I and actin are required for transcription of ribosomal genes.

Maria Malanga: Poly(ADP-ribose) reactivates stalled DNA topoisomerase I: relevance to genomic stability and cancer therapy.

Marek Gniazdowski: Covalent binding of amidine analogues of anthracyclines to DNA.

Transgenic Organisms in Agrobiotechnology and Medicine - Centre of Excellence PAGEN Workshop on Modifications of commercially Valuable Plants

Bernd Müller-Röber: Transcription factor function search: combining genomics and single-gene approaches to discover new regulatory networks in plant biology.

Holger Hesse: Transgenic plants as a tool to improve sulfur amino acid content in plants.

Urte Schlüter: Manipulation of flax for improved fibre extractability.

Jan Szopa: Flax engineering for fiber improvement.

Marcin Łukaszewicz: The antioxidant potential of transgenic plants.

Jacek Hennig: Functional analysis of gluB gene in Solanum tuberosum plants.

Janusz Zimny: Transgenic crops in the world.

Modern Trends in Diagnosis and Therapy of Cancer

Beata Utracka-Hutka: Targeted therapy.

Adam Maciejewski, Bogusław Mąka: Reconstructive surgery.

Rafał Tarnawski: Radiosurgery.

Brygida Białas: Real-time brachytherapy of prostate cancer.

Barbara Jarząb: Expression profiles in papillary thyroid cancer analysed by DNA microarrays.

Maciej Małecki, Przemysław Janik: Angiogenic gene therapy: a bicistronic strategy.

Małgorzata Wierzbicka: Biological implications of failures in solid tumours treatment.

DNA repair and their role in carcinogenesis

Ryszard Oliński: The molecular links between oxidative damage to DNA and cancer.

Marcin Kruszewski: Labile iron pool, oxidative DNA damage and carcinogenesis.

Miroslav Chovanec: DNA double-strand break repair and its implication in cancer.

Rosa Goncharova: Some aspects of applying antimutagens as anticarcinogens.

Joanna Rzeszowska-Wolny: Nucleotide excision repair – new role in oxidative damage repair?

Marek Rusin: DNA repair genes; polymorphisms and risk of cancer.

Mathematical Models of in Biology and Medicine

Jacek Leluk: Wrong assumptions and misinterpretations in molecular biology, biochemistry and bioinformatics.

Aleksander Masny, Andrzej Płucienniczak: PCR performed at low denaturation temperatures – PCR melting.

Joanna Polańska: Using Gaussian mixtures to infer structure in microarray data.

Tomasz Magdziarz: Designing drugs by docking ligands into proteins - chemical problems and technical challenges.

Marcin Pacholczyk: Analysis of differences in protein substitution patterns based on statistical tests.

Satellite workshop: Cytogenetic Markers in Assessment of Human Exposure to Carcinogenic Substances

Maria Sąsiadek: Chromosomal aberrations and cancer risk.

Maria Dušinská: Assessment of biomarkers of exposure, effect and individual susceptibility in workers exposed to mineral fibres.

Francesca Marcon, Riccardo Crebelli: Can current biomarkers be applied in the monitoring of low environmental exposures? Results from an investigation on traffic wardens of Rome city.

Grażyna Motykiewicz: Application of cytogenetic markers in the polluted region of Upper Silesia.

Elżbieta Skrzydlewska: Green tea in cancer prevention.

(VIII) Gliwice Scientific Meetings 2004

19-20.11.2004

Mathematical Models in Genomics and Cancer Biology Session supported by Apple IMC Poland SAD

Michał Dąbrowski: Identification of potential cis-regulatory features associated with a mode of gene expression common to neuronal differentiation and hippocampal development.

Krzysztof Fujarewicz: Identification of models of cell signaling pathways.

Piotr Formanowicz: Isothermic sequencing by hybridisation.

Krzysztof Simek: SVD as a tool for pattern discovery in gene expression data.

Bogdan Smołka: Fast denoising of cDNA microarray images.

Structure and Function of the Genome

Sergey Razin: The spatial organization of DNA in eukaryotic cell nuclei plays an important role in determining positions of recombination hot-spots.

Jan Filipski: Epigenetic regulation of transcription and the origin of isochors.

Piotr Widłak: The other face of histone H1.

Vasyl F. Chekhun: New trends in experimental oncology in Ukraine.

New concepts and methods

Lise L. Hansen: PCR amplification of highly GC-rich templates. An efficient tool in the search for new prognostic markers in cancer.

Janusz M. Bujnicki: Protein structure prediction by consensus fold recognition and assembly of fragments.

Gabriel Wcisło: From molecular studies to clinical practice. An EGFR (epidermal growth factor receptor) story.

DNA Repair Mechanisms and their Role in Carcinogenesis

Antonina Cebulska-Wasilewska: Response to challenging dose of x-rays as biomarker of susceptibility in molecular epidemiology.

Wolfgang Goedecke: The fate of DNA double-strand breaks: aspects of mitotic and meiotic cells.

Andrzej Wójcik: Do interindividual differences in lymphocyte chromosome radiosensitivity exist?

Ulla Kasten-Pisula: Molecular mechanisms of the individual radiosensitivity: impact on DNA repair.

Paweł Jałoszyński: Fidelity or survival? How unrepaired DNA is replicated when polymerases encounter problems.

Barbara Tudek: Processing of lipid peroxidation-derived DNA adducts by repair enzymes and DNA polymerases.

Miroslav Chovanec: Repair of DNA double-strand breaks of different origin in Saccharomyces cerevisiae.

Cellular Stress, Signaling Pathways and Cancer Session supported by Committee for Human Genetics and Molecular Pathology, PAS

Maciej Żylicz: Hsp70 and MDM2 are important for the transcriptional activity of wild type p53.

Joanna Rzeszowska-Wolny: Gene expression profiles and cellular stress.

Svetlana Sidorenko: CD150-mediated signaling.

Lyudmila Sidorik: The role of molecular chaperons in cancer.

Jekaterina Erenpreisa: Expression of meiotic genes and phenotype by irradiated tumour cells.

Functional Genomics in Medicine Session supported by State Committee for Scientific Research (Grant PBZ-KBN-040/PO4/2001)

Barbara Jarząb: Genomic approach to thyroid cancer.

Małgorzata Wiench: RET protooncogene and gene expression profile of thyroid cancer.

Joanna Polańska: Applications of mixture models to gene expression profiles.

Katarzyna Lisowska: Gene expression profiling in hereditary breast cancer; preliminary results.

Michał Jarząb: From microarray data to the biological relevance.

(IX) Gliwice Scientific Meetings 2005 The 80th Anniversary of Professor Mieczysław Chorąży

18-19.11.2005

Structure and Function of the Genome - Epigenetic Mechanisms

William T. Garrard: Mechanisms of activation and silencing of the immunoglobulin kappa locus.

Andrzej Jerzmanowski: Chromatin remodeling and linker histones in plant development.

Sergey Razin: Assembly of nuclear matrix - bound protein complexes involved in non-homologous end joining is induced by inhibition of DNA topoisomerase II.

Harry Sherthan: Satellite DNA, meiotic telomeres and chromosome evolution.

Jan Barciszewski: Diagnosis and therapy of brain tumors.

Response to Stress and Alterations of Genome and Transcriptome in Cellular Pathology

Lise Lotte Hansen: Genomic instability of the HCP region in somatic breast cancer.

Ryszard Oliński: Clinical significance of oxidative DNA damage.

Krzysztof Szyfter: Progression of head and neck cancer studied by molecular cytogenetics.

Stanisław Cebrat: The role of crossing-over in the computer simulated populations.

Protein Sciences in Biology and Medicine

Alfred Pingoud: Engineering of meganucleases.

Janusz M. Bujnicki: Protein structure prediction by combination of fold-recognition and de novo holding.

Jerzy Ostrowski: Strengths and limitations of microarray- and mass spectrometry-based methods in clinical research.

Michał Dadlez: Application of mass spectrometry for the studies of proteomes.

Krzysztof Puszyński: Logical analysis of proteomic data.

Marcin Pacholczyk: Some algorithms of molecular docking.

Therapeutic Strategies and Mathematical Models in Contemporary Oncology

Pedro de Campos-Lima: New strategies in therapy of virus-caused tumors

Marek Los: Apoptin - a novel, cancer-selective killer

Andrzej Świerniak: Antiangiogenic therapy as a control problem

Anna Marciniak-Czochra: A simple mathematical model for cell signaling in radiation experiment

Piotr Czerski: Sekwencjonowanie i synteza DNA

Sympozjum satelitarne:

Nowe leki i strategie terapeutyczne we współczesnej onkologii

Piotr Wysocki: Efekt przeciwnowotworowy kaptoprilu – druga strona medalu.

Elżbieta Pajtasz-Piasecka: Aktywność przeciwnowotworowa szczepionki na bazie komórek dendrytycznych transdukowanych genami mysiej IL-12 lub IL-2 u myszy z zaawansowanym nowotworem MC38.

Dominika Nowis: Badanie mechanizmów niszczenia komórek nowotworowych przez terapię fotodynamiczną oraz próby potęgowania jej efektywności.

Danuta Duś: Białka oporności wielolekowej w komórkach macierzystych krwi.

Maciej Ugorski: Wykorzystanie RNAi do hamowania ekspresji glikozylotransferaz.

Joanna Wietrzyk: Toksyczność nowych analogów witaminy D i ich aktywność in vitro w terapii kombinowanej z cytostatykami w modelu raka gardła.

Katarzyna Szczaurska: Aktywność przeciwnowotworowa bakteriofagów w terapii skojarzonej z cytostatykami.

Janusz Boratyński: Koniugaty metotreksat – nośnik – właściwości chemiczne i biologiczne.

Aleksandra Rusin: Przeciwnowotworowe i przeciwzapalne właściwości nowych koniugatów niesteroidowych leków przeciwzapalnych i oligomerów 3-hydroksymaślanu.

Tomasz Cichoń: Kombinacja cyklofosfamid z cytokinami indukowanymi przez sekwencje CpG DNA w hamowaniu wzrostu doświadczalnych przerzutów czerniaka B16(F10) w płucach myszy.

(X) Gliwice Scientific Meetings 2006 The 10th Anniversary of Gliwice Scientific Meetings

17-18.11.2006

Cell Signaling and Responses to Stress

Carmel Mothersill: Radiation induced bystander effects in vivo – are they protective or destructive?

Maciej Żylicz: Role of molecular chaperones in cell transformation.

Anna von Mikecz: Quality control in the cell nucleus by the ubiquitin-proteasome system.

Ryszard Oliński: Oxidative DNA damage; cause or consequence of cancer?

Barbara Tudek: Modulation of oxidative DNA damage repair by oxidative stress and neoplastic transformation.

Jolanta Barańska: Nucleotide receptors and their role in cellular signaling in glioma C6 cells.

Joanna Rzeszowska-Wolny: Intercellular communication in X-irradiated cells and its influence on gene expression profiles.

Jarosław Śmieja: What mathematical modeling can help with in analysis of signaling pathways? (Lessons from modeling

of IFN- pathway).

Cell Death and Aging

Ding Xue: Coordination of apoptotic DNA degradation and cell corpse engulfment in C. elegans.

Ewa Sikora: What if not apoptosis?

Andrzej M. Składanowski: Too many ways to die: cell death-cell survival dilemma in cancer chemotherapy.

Gregor Meiss: Structure-function relationships in DNA-fragmentation factor.

Piotr Widłak: Does active DFF need regulation? (How many steps for regulation of apoptotic nucleases?)

Modern Trends in Cancer Diagnostics and Therapy

Barbara Jarząb: Cancer transcriptome: factors determining gene expression profiles.

Marek Jakóbisiak: Prospects of cancer immunotherapy.

Marek Los: Hijacking cell survival pathways to selectively kill cancer cells.

Hanna Rokita: Immunotherapy of neuroblastoma with peptide vaccines based on molecular mimicry of GD2 gangliosides.

Aleksander Sieroń: Zinc-dependent metalloproteases and their inhibitors in biology and diagnostics of cancer.

Rafał Tarnawski: Modern radio-oncology.

Frank Koltrowitz: The experimental power of MACSmolecular gene expression analysis products.

Biotechnologia w Polsce – perspektywy rozwoju i problemy dydaktyczne

Technologia:

Andrzej Pilc: Nowe leki antypsychotyczne

Stanisław Bielecki: Możliwości zewnętrznego i wewnętrznego stosowania celulozy mikrobiologicznej w medycynie

Andrzej Płócienniczak: Produkcja ludzkiego hormonu wzrostu

Jan Szopa: Genetyczne modyfikacje roślin uprawnych

Bernard Korzeniewski: Analiza kontroli metabolicznej a biotechnologia

OLYMPUS Optical: FluoView 1000 – nowa jakość w mikroskopii konfokalnej

Edukacja:

Jacek Leluk: Zdalne nauczanie wczoraj, dziś i jutro.

Amalia Guzdek: Biotechnologia w Uniwersytecie Jagiellońskim - dekada nauczania.

Andrzej C. Składanowski: Patologia molekularna - jak są nauczani studenci Międzyuczelnianego Wydziału Biotechnologii Uniwersytetu Gdańskiego i Akademii Medycznej w Gdańsku - analiza SWOT

Perspektywy:

Korneliusz Miksch: Rola biotechnologii w zrównoważonym rozwoju województwa śląskiego

Ludwik Tomiałojć: Ekologiczne i ekonomiczne źródła obaw przed szybkim wprowadzaniem upraw GMO

Mieczysław Chorąży: Modyfikacje genetyczne – nadzieje i obawy

XIth Gliwice Scientific Meetings 2007 Molecular Biology and Bioinformatics in Cancer Diagnostics and Therapy

16-17.11.2007

Modeling and Synthetic Approaches in Drug Discovery

Johann Gasteiger: Explorations into biochemical pathways.

Beata Walczak: A start-to-end approach to the analysis of proteomic data.

Jaroslaw Polanski: The design and discovery of HIV integrase inhibitors.

Alicja Ratuszna: The new photosensitizers and their application in Photodynamic Therapy.

Timothy Madden: An approach to drug development in an academic environment.

Waldemar Priebe: Design and development of novel anticancer drugs for treatment of brain tumors.

Bogdan Lesyng: Oncogenic JAK/STAT signalling pathways and design of JAK-kinase inhibitors.

Grzegorz Grynkiewicz: Sugars in new drug design – a lesson from natural products with anticancer activity.

Wiesław Szeja: Glycoconjugates. Development of a new biologically active compounds.

New Trends in Cancer Diagnostics and Therapy

Thoralf Christoffersen: Mechanisms integrating signalling from G protein-coupled receptors and EGF receptors in normal and malignant gastrointestinal cells.

Dagny Sandness: Role of different prostanoid receptors in the growth-stimulatory effects of prostaglandins.

Barbara Tudek: DNA repair in the pathology of lung and colon cancer.

Carmel Mothersill: Harnessing low dose radiation responses for radiation protection.

Colin Seymour: Natural products as radiation response modifiers.

Raisa Smolyakova: Prognostic molecular biologic markers in breast cancer.

Walter Mier: The potential of endoradiotherapy for the development of highly specific cytostatics.

Dariusz Iżycki: Genetic antimelanoma vaccines - promises and obstacles.

Marek Los: Targeted cancer therapies using derivates of natural products – Brevinin-2R and Apoptin as examples.

Maciej Giefing: Array-GCH based identification of oncogenes and tumor suppressor genes involved in laryngeal cancer.

Maria Obolenskaya: Novel approach in the study of IFN alpha activity.

Krzysztof Puszyński: Deterministic model of p53|Mdm2 signaling pathway.

Ion Channels in Biology and Medicine

Mustafa B. A. Djamgoz: Voltage-gated Na channel upregulation and potentiation of cellular behaviours in metastatic disease.

Zbigniew Grzywna: Wound healing as a diffusional sorption process.

Steven White: Making sense of voltage sensors.

Jerzy Mozrzymas: Pharmacokinetic description of GABAergic current modulation by benzodiazepines in neurons.

Maria Mycielska: Metabolic pathways in human prostate cancer cells: regulation by voltage-gated Na channel activity.

Krzysztof Dołowy: Ion channels and genetic disorders – the cystic fibrosis case.

Genomics and Proteomics in Medicine

Adam Godzik: Metagenomics provides new perspectives on human health.

Daria Handkiewicz-Junak: Molecular PET imaging and gene expression profiling of malignant tumors.

Krzysztof Fujarewicz: Monte Carlo methods for genomic data analysis.

Piotr Widłak: Mass Spectrometry analyses of the serum proteome - an important tool of clinical proteomics.

Joanna Polańska: Application of the Gaussian mixture model to proteomic MALDI-ToF mass spectra.

Tomasz Bieńkowski: Discovery and validation of biomarkers by Mass Spectrometry.

Jacek Leluk: Theoretical background and utility of commonly used sequence multiple alignment tools.

David Hulmes: Controlling the assembly of the cellular microenvironment and applications in tissue regeneration and repair.

Aleksander Sieroń: Genetic engineering of ECM compounds for regenerative medicine.

Marek Kowalczuk: Biopolyesters and their synthetic analogues of controlled structure at the molecular level for regenerative medicine.

Anna Szydło: Copolymers of synthetic biodegradable scaffold with collagen type I.

Ksymena Urbanek: Characterization of nonadherent rat bone marrow stem cells (VSEL cells).

XIIth Gliwice Scientific Meetings 2008

21-22.11.2008

Responses to Ionizing Radiation and DNA Damage

Kevin Prise: New insights on bystander signalling: The role of DNA damage sensing and repair.

Carmel Mothersill: Bystander effects and adapative responses induced by radiation exposure.

Marie Boyd: Bystander effects and targeted radiotherapy for gliomas.

Joanna Rzeszowska-Wolny: Transcription profile change after irradiation or in bystander cells; differences between cell lines.

Rachel Martin: Characterizing protein post translational modifications using MALDI mass spectrometry.

Beata Walczak: Proteomics: automated electro-phoregram analysis.

Chryso Kanthou: Response of the tumour vasculature to radiation and vascular disrupting agents.

Walter Mier: The targeting of melanoma for endoradiotherapy.

Micheline Giphart-Gassler: Towards a gene expression profile to classify patients for normal tissue toxicity.

Molecular Channels

Mustafa B.A. Djamgoz: Voltage-gated ion channels as mediators of growth factor effects in metastatic disease.

Adam Szewczyk: Mitochondrial potassium channels.

Maria Mycielska: Citrate transport in human prostate cancer cells: regulation by functional voltage-gated Na+ channel expression.

Krzysztof Dołowy: The role of mitochondrial ion channels in ischemic preconditioning.

Systems Biology, Bioinformatics and Signaling Pathways

Miguel Rubi: Somatic exocytosis of serotonin mediated by molecular motors.

Jerzy Mozrzymas: Impact of acidosis on modulation of GABAergic IPSCs by benzodiazepine receptor agonists.

Jerzy Jurka: Mobile DNA elements throughout evolution.

Maria Obolenskaya: Folate-related metabolism in human placenta.

Jan Poleszczuk: Tumor development model under angiogenic signaling with dependence on vessel impairment.

New Drugs and Treatments

Ryszard Oliński: Oxidative processes and cancer.

Jean Francois Mouscadet: in silico study suggests that Raltegravir-resistant mutations modify the DNA recognition properties of HIV-1 integrase.

Marek Los: Apoptin and its derivatives as molecular templates for the development of Bcr-Abl kinase inhibitors.

Alexa Schieck: Identification of the determinant of hepatitis B virus liver tropism and its implications for hepatocyte-specific drug targeting.

Martin Dolezal: Biologically active pyrazines, the past and the future.

Experimental Biotechnology

Wiesław Szeja: Synthetic glycomix for mining natural products as drug leads. Part I.

Grzegorz Grynkiewicz: Synthetic glycomix for mining natural products as drug leads. Part II.

Aleksandra Rusin: Genistein derivatives and their biological activity.

Krystiana Krzysko: Binding of genisteine derivatives to abl and lck protein kinases, and to microtubules - modelling studies.

Andrzej Gamian: Glycation of proteins as their modification in physiology and disease.

Olena Palyvoda: Molecular organization in self-assembled monolayers used for neuronal cell growth.

Joanna Polańska: Statistical processing of DNA microarray data - detecting subtle changes of gene expressions.

XIIIth Gliwice Scientific Meetings 2009

20-21.11.2009

2nd Polish-German Cancer Workshop

Molecular Epidemiology of Cancer

Kari Hemminki: Genetic basis of familial aggregation of cancer.

Jan Lubiński: The latest advances in clinical genetics of tumors including gastric cancer.

Ute Hamann: Search for modifiers of hereditary breast cancer risk.

Asta Försti: Evidence for genetic basis in breast cancer survival.

Ewa Grzybowska: Molecular epidemiology of hereditary breast and ovary cancer in Silesia, clinical course of breast and ovary cancer in respect to polymorphisms of PGR and MDR1 genes.

Annekatrin Lukanova: Pregnancy hormones and maternal cancer.

Dorota Butkiewicz: Genetic influences on survival in lung cancer.

Federico Canzian: Genome-wide studies in cancer.

Krzysztof Szyfter: Identification of laryngeal cancer-related genes using high resolution array-CGH technique.

Functional Genomics in Cancer Research

Stefan Wiemann: Modeling and testing of cell cycle regulation via the ErbB protein and miRNA network in breast cancer.

Aurelio Teleman: Identification of a phosphatase regulating insulin signaling.

Marcin Szaumkessel: Pyrosequencing-based DNA methylation profiling of Fanconi anemia/BRCA pathway genes in head and neck squamous cell carcinoma.

Sandra Steinbrink: Genome-wide functional screens to identify novel factors in cancer pathways.

Joanna Polańska: New mathematical approaches in analyses of genomic and proteomic data.

Barbara Jarząb: Thyroid carcinoma as a model for gene expression profiling of cancer.

Jörg Hoheisel: Functional genomics and proteomics in pancreatic cancer research.

Jolanta Kupryjańczyk: Prognostic and predictive factors in ovarian cancer – results of verification of DNA microarray data.

Magdalena Skrzypczak, Jerzy Ostrowski: Potential and challenges of microarray data

analyses for predicting oncogenic signaling in colon tumors.

Anna Fiszer-Kierzkowska: Molecular profiling of histopatologically normal prostate tissue adjacent to cancer.

Piotr Widłak: MALDI-TOF MS-based serum proteome pattern analysis in molecular diagnostics of breast cancer.

Molecular Biology, Biotechnology and Bioinformatics in Cancer Diagnostics and Therapy.

Bystander Mechanisms as Targets for Cancer Radiotherapy

Carmel Mothersill: Targeting bystander signalling and response pathways for cancer drug development.

Marie Boyd: Bystander effects elicited by different radiation qualities - therapeutic opportunities?

Elisabeth Schueltke: Synchrotron radiotherapy for human glioma: role of bystander mechanisms.

Mansoor Ahmed: High-dose lattice radiation therapy: clinical, physics and biological perspective of bystander effects.

Wojciech Jurczak: Haematologic toxicity of radioimmunotherapy.Colin Seymour: Radiation-induced bystander effects in vivo: possible novel targets.

James Murphy: Low LET radiation and bystander factor damage to mammalian mitochondria.

Bruce C. McKay: Targeting transcription-coupled repair as an anti-cancer strategy.

Anna Marciniak-Czochra: Characterization of the hematopoietic stem cells using mathematical models.

Krzysztof Puszyński: Crosstalk between p53 and nuclear factor-kappaB systems: pro- and anti-apoptotic functions of NF-kB.

Joanna Rzeszowska-Wolny: Blood cells, can they be important in bystander effects?

Ion Channels and Cancer

Miquel Rubi: A thermodynamic description of active transport through channel proteins.

Walter Stühmer: A potassium channel involved in cancer.

Maria Mycielska: Cloning and characterization of citrate transporter and its K regulatory component in prostate and prostate cancer.

XIVth Gliwice Scientific Meetings 2010

26-27.11.2010

Stress Response Mechanisms and Their Usefulness in Prediction of Cancer Response to Therapy

Luciene Zanchetta: Simulated sunlight-induced damage to mitochondria and mtDNA in human skin cells.

Geza Sáfrány: Low dose radiation induced transcriptional alterations in bystander primary human fibroblast cells.

Carmel Mothersill: Issues in the interpretation of low dose effects in radiobiology and environmental radiation protection.

Colin Seymour: Update on communication of bystander signals between organisms.

Rob Mairs: Potent bystander effects are induced by targeted radionuclides.

Joanna Rzeszowska-Wolny: Oxidative stress and bystander effect.

Lyudmila Drobot: The oncogenic potential of adaptor protein Ruk/CIN85 in human breast adenocarcinoma.

New Drugs and Treatments

Ross Hannan: Transcription by RNA polymerase I as target for anticancer therapy.

Wiesław Szeja: Synthesis and biological activity of genistein glycosides and glycoconjugates.

Ilona Wandzik: Synthesis of complex derivatives of uridine as potential inhibitors of glycosyltransferases.

Aleksandra Rusin: Biological activities of synthetic genistein derivatives.

Molecular Modeling and Bioinformatics Tools

Andrzej Polanski: Large scale searching for exact tandem repeats in genomes based on the Burrows - Wheeler transform algorithm.

Krzysztof Fujarewicz: Genomic data analysis with bootstrapping.

Jacek Koronacki: A reliable and simple approach to feature selection and interdependency discovery in supervised classification.

Mateusz Gałuszka: CLC bio-specialized software solutions for genetics and genomics.

William Amos: Exploring patterns of non-randomness in human mutations.

Olivier Lichtarge: Evolution: a guide to protein function and its redesign.

Marek Kimmel: Patterns of evolution of human genetic disease with implications for deep sequencing methods.

XVth Gliwice Scientific Meetings 2011

18-19.11.2011

Mechanisms of Metastasis session co-organized by EACR members

Claudine Kieda: Tumour angiogenesis normalization in the prevention of metastasis.

Angels Sierra: Brain metastasis proteins and their interactions: a rational predictive biomarkers research.

Ingeborg Tinhofer: Incidence and prognostic role of circulating tumor cells in squamous cell carcinoma of the head and neck region.

Lyudmila B. Drobot: The biological role of adaptor/scaffold protein ruk/cin85 in breast carcinogenesis.

Marek Los: Attempts to target cancer stem cells. Salinomycin as an example.

Maciej Ugorski: The role of ceramide galactosy-ceramide (UGT8), a new molecular marker of breast cancer malignancy, in cancer progression.

Regulation of Gene Expression at the Transcript Level

Martin Simard: Understanding RNA silencing pathways through the Argonaute proteins.

Gunter Meister: Analysis of Argonaute interactions in mammalian cells.

Petr Svoboda: Unique regulation of small RNAs during oocyte-to-embryo transition in mammals.

Anna Kurzyńska-Kokorniak, Marek Figlerowicz: Modulation of microRNA biogenesis by using short oligo-RNA molecules.

Krystian Jażdżewski: The role of microRNA sequence variation in thyroid cancer.

Witold Konopka: Hypothalamic miRNA suppresses obesity in mice.

Ana Kozomara: The miRbase and the deep-sequencing data.

Kathrin Leppek: Roquin promotes rapid TNF mRNA degradation via a stem-loop recognition element.

Joanna Rzeszowska-Wolny: MicroRNA and RNA oxidative damage.

Genes and Response to Radiation: Low Doses, Bystander Effects

Carmel Mothersill: Emerging issues in radio-biology – the impact of non-targeted effects.

Marek K. Janiak: Antineoplastic effects of low-level exposures to ionizing radiation.

Marek Kimmel: Spatial and stochastic effects in models of cell interaction

Andrzej Świerniak: Bystander effect modeling using evolutionary games.

Tomasz Wojdyła: Investigating the genealogical relationship among Slavs, Balts and Finns using demographic network model.

Maria Wideł: Protective bystander effect.

Piotr Widłak: Radiation-related changes in serum proteome profiles detected by MS in blood of patients treated with RT due to larynx cancer.

Colin Seymour: The Ego, The Id, and Radiotherapy.

Polish-German-American Workshop on Progress in Neurooncology: From the Bench to the Clinic

Brain tumours biology

Bożena Kamińska-Kaczmarek: Glioma initiating cells and immune microenvironment of gliomas.

Marcel Kool: Integrated genomics on molecular subtypes in medulloblastoma.

Stanisław Szala: Tumor vasculature in malignant gliomas.

Frank Winkler: New insights into brain tumor biology by intravital microscopy.

Klaus-Rudiger Trott: Why gliomas are radioresistant?

Amir Abdollahi: Next Generation NeuroRadioOncology.

Diagnostics and Therapy

David Capper: Visualizing mutations: application of IDH1 and BRAF mutation specific antibodies in neuropathology.

Barbara Bobek-Billewicz: Brain tumor properties to be identified by MRI - not always a success story.

Henryk Majchrzak: Progress in surgical treatment of low grade gliomas.

Pawel Nauman: Different aspects of surgery for primary brain tumours.

Volker Budach: Radiosurgery and fractionated radiotherapy of benign brain tumours.

Rafał Tarnawski: Prophylactic cranial irradiation with dose reduction in regions of active neurogennesis - a pilot study for SCLC patients with metastases in brain.

Novel Therapeutic Modalities

Volker Budach: Nano-Thermo-Radiotherapy or recurrent gliomas – results of a new therapeutic modality.

Timothy Madden: Translating innovative therapies for CNS malignancies - overcoming impediments.

Charles Conrad: Oncolytic adenovirus therapy for brain tumors: a guide for development from the bench to the bedside in the academic setting.

Waldemar Priebe: Discovery and development of novel therapies for brain cancer.

XVIth Gliwice Scientific Meetings 2012

16-17.11.2012

Structure of the Nucleus and Regulation of Gene Expression

Jan Brzeski: Maize in the maze: a rough guide to the puzzling epigenetics of paramutation.

Sergey Razin: Folded chromatin domain instead of an active chromatin hub: a model based on reconsidered essentials of the chromosome conformation capture procedure.

Sławomir Kumala: The influence of chromatin topology on the accessibility of DNA to damage.

Ronald Hancock: New models of the nucleus and chromosomes.

Cellular Responses to Ionizing Radiation and Stressing Factors session co-organized by EACR members

Mary Helen Barcellos-Hoff: Microenvironment matters: contributions to radiation carcinogenesis.

Carmel Mothersill: Transmission of signals from irradiated rats to cage mates: an inter-animal bystander effect.

Colin Seymour: The first cut is the deepest.

Barbara Tudek: Repair of oxidative DNA damage during development of colon cancer.

Selectively Cytotoxic Proteins

Mathieu H. Noteborn: Apoptin induces cell death by targeting various tumor processes.

Mahvash Tavassoli: Human Gyrovirus Apoptin shows a similar function to VP3/Apoptin.

Stian Knappskog: Inactivation of the TP53 gene or the p53 regulators Chk2 / ATM predicts resistance to anthracyclines in breast cancer.

Marek Los: Modeling of interaction between BCR-ABL and apoptin - novel way for argeting the deregulated Abelson kinase activity.

Proteomics session co-organized by Polish Society of Proteomics

Andreas Rőmpp: High resolution mass spectrometry imaging – comprehensive and specific histological information at cellular resolution.

Jacek R. Wiśniewski: Quantitative study of colorectal cancer to a depth of 10,000 proteins using laser microdissected formalin fixed and paraffin embedded tissue.

Marcus Macht: Proteomics through integrated MALDI and ESI.

Jerzy Silberring: Rapid analysis of drugs of abuse as an initial step towards predictive toxicology.

Łukasz Marczak: Mass spectrometry based analysis of protein N-homocysteinylation.

Joanna Polańska: Detection and quantification of MALDI ToF spectral peaks by using Gaussian mixture decomposition.

Piotr Widłak: Mass profiling of cancer serum proteome - does it provide any useful information?

Systems Biology

Mieczysław Chorąży: The systems biology: introductory remarks.

Izabela Makałowska: Retrogenes – trash or treasure?

Marek Rusin: Cross-talk between p53 and Akt kinase pathways.

Joanna Janiszewska: microRNAs and their importance in laryngeal carcinoma.

Marek Kimmel: Variability and homeostasis in cycling cell populations.

Andrzej Świerniak: Extended model of interaction between tumour cells.

XVIIth Gliwice Scientific Meetings 2013

15-16.11.2013

Regulation of Gene Expression and Replication

Anke van den Berg: The role of microRNAs in B cell Hodgkin and non-Hodgkin lymphoma.

Joost Kluiver: Long noncoding (lnc)RNAs: novel players in B-cell lymphoma.

Małgorzata Czyż: Heterogeneity of melanospheres: therapeutic implications.

Krzysztof Puszyński: Dynamics of intracellular processes.

Cellular Pathways Driven by Reactive Oxygen Species

Sebastian Student: Reactive oxygen species in the nucleus and cell death.

Carmel Mothersill: Radiation-induced non-targeted effects: horizontal and vertical transmission of genetic change mediated by oxidative stress?

Barbara Tudek: Lipid peroxidation modulates DNA repair and sensitizes cells to genotoxic factors.

Natasha Kopitar: Deletion of stefin B gene enhances mitochondrial ROS formation and Nlrp3 inflammasome activation.

DNA Repair in Aging and Cancerogenesis

Leon H Mullenders: Spot on the DNA damage response: from lesion recognition to human disease and therapy.

Wojciech Niedźwiedź: BLM collaborates with TOPBP1 in promoting checkpoint activation and replication fork stability.

Miroslav Pirsel: DNA repair helicase – the story with an unexpected end.

Grażyna Mosieniak: DNA damage response in cancer cell senescence.

Cancer Proteomics and Metabolomics session co-organized by Polish Society of Proteomics

Corinna Henkel: MALDI imaging in clinical research: searching for the Holy Grail.

Angels Sierra: Proteins and protein-protein interacting motifs to therapeutic target of metastasis.

Tone F. Bathen: Metabolic profiling of breast cancer.

André Goffeau: Targeting selectively the unique energy metabolism of cancer with a small molecule inhibitor.

Andrzej Swinarew: The instrumental analysis of novel polymeric materials for bioapplications.

Dietary Factors in Cancer Prevention session co-organized by EACR members

Wanda Baer-Dubowska: Diet and cancer: from epidemiological data to mechanism-based cancer prevention.

Adriana Albini: The tumor microenvironment as target for cancer therapy and prevention by dietary components.

Karen Brown: Development of resveratrol for cancer chemoprevention.

Albena Dinkova-Kostova: Chemoprevention against cancer by isothiocyanates.

Jędrzej Antosiewicz: Chemoprevention of prostate cancer by organosulfur compounds from garlic.

Wim Van den Berghe: Promises & challenges in epigenetic remodeling of breast cancer metastasis by natural withanolides from Withania somnifera (Ashwagandha).

Agnieszka Bartoszek: Discoveries of experimental chemoprevention - how to exploit them in rational design of health quality and therapeutic foods.

Cancer Killing

Sun Xiao-Feng: Biomarkers in colorectal cancer.

Marek Los: Salinomycin – experimental drug with preferred toxicity towards cancer stem cells, the role of autophagy in salinomycin toxicity.

Nikolaos Sfakianakis: Numerical study of cancer invasion of extracellular matrix.

Katrina Erenpreisa: Senescence, polyploidy, and stemness – three components of the response of tumour cells to DNA damage.

Kourosh Lotfi: P-glycoprotein transport of the active imatinib metabolite, CGP-74588, in chronic myeloid leukemia cells.

Jerzy Pieczykolan: Evaluation of novel, anticancer, targeted fusion biomolecule with high antiangiogenic and cytotoxic activity – summary of preclinical findings.

XVIIIth Gliwice Scientific Meetings 2014

21-22.11.2014

Transcriptional Responses to Stress

Allan R. Brasier: NF-kB signaling and the innate immune response.

Neil D. Perkins: Regulation of cancer cell proliferation and survival by NF-kB.

Bożena Kamińska: Transcriptional and epigenetic mechanisms controlling inflammation.

Marek Kimmel: Simplicity and complexity in models of cell signaling.

Tomasz Lipniacki: NF-kB and IRF3 crosstalk signaling in MEFs.

Mariusz Hartman: Immediate and long-term molecular response of melanoma cells to changes in microenvironment.

Biomaterials and Nanomedicine

Mehrdad Rafat: Bioengineered collagen constructs for cell-based regeneration of the cornea.

Katerina Chlichlia: Magnetic and biogenic nanoparticles for cancer therapy.

Ramunas Valiokas: Biopatterning techniques in tissue engineering.

Łukasz Zarodkiewicz: AFM-IR: Combining atomic force microscopy and infrared spectroscopy for multifunctional measurements – nanoscale chemical characterization.

Glycobiology in Medicine

Anna Lityńska: The role of aberrant glycosylation in human melanoma progression to more malignant phenotype.

Marcin Czerwiński: Glycosyltranferases and blood group antigens.

Wojciech Jachymek: Bacterial glycomics: new approach to vaccine production.

Yanusz Wegrowski: Matrix proteoglycans as regulators of tumor progression.

Bioinformatics and Regulatory Mechanisms

session co-organized by EACR members

Till Bretschneider: Image-based modeling of cell motility.

Sascha Ott: Analysis of DNase-seq data.

Franck Delaunay: Multispectral fluorescent single live cell imaging to analyse the cell cycle and the circadian clock dynamics.

Carmel Mothersill: Radiation-induced bystander signals: evidence for a role of secondary UVA emission in the generation of oxidative stress and bystander effects by beta irradiation of human keratinocytes.

Piotr Formanowicz: Petri net based approach for modeling and analysis of selected aspects of atherosclerosis.

Krzysztof Kucharczyk: Minor genetic variants discovery and detection down to 0,1% level at the heterogenic tumor material by the MSSCP method.

Michal Braczkowski: Application of ROCHE Diagnostics products for gene expression studies.

Satellite Workshop:

Genes – Environment Interactions

Maria Dusińska: Challenges with gene-environment interactions: Where we are and where we need to go?

Sofia Pavanello: Monitoring of exposures to carcinogens: Does the procedure need a rethink?

Karin Broberg-Palmgren: Epigenetics of metals.

Natalia Pawlas: Genetic susceptibility to metals.

Süreyya Meriç Pagano: Multi-bioassay toxicity evaluation of a mixture of different group of pharmaceuticals.

Norbert Kreuzinger: Wastewater treatment plants as a hub between clinical and environmental antibiotic resistance.

Aneta Łuczkiewicz: Human-associated bacteria and their mobile genetic elements - important minority in wastewater and wastewater impacted ecosystems.

Aleksandra Ziembińska-Buczyńska: Antibiotics and their resistance genes in the environment – bacterial opportunity or threat?

XIXth Gliwice Scientific Meetings 2015

20-21.11.2015

Intra-Tumor Heterogeneity and Evolution

session co-organized by EACR members

Urszula Hibner: Cancer and evolution.

Anna Golebiewska: Clonal evolution meets cancer stem cells: in-depth analysis of genetic and phenotypic heterogeneity in glioblastoma.

Gareth Wilson: Deciphering cancer genome evolution and intra-tumour heterogeneity.

Trevor Graham: Intra-tumour heterogeneity as a pan-cancer prognostic biomarker.

Bożena Kamińska-Kaczmarek: Cancer stem cells and immune microenvironment.

Anke van den Berg: Genomic inter- and intra-tumor heterogeneity in primary lung cancer and its metastasis.

Kathrina Erenpreisa: Sub-cellular heterogeneity and asymmetry in fate choice of irradiated HeLa and etoposide-treated ovarian teratocarcinoma PA1 cells.

Marek Los: Generation of limbal epithelial cell progenitors by two methods: by differentiation from iPS cells and by direct trans-differentiation from human dermal fibroblasts.

Radiation Biology

Serge Candeias: Effects of low dose radiation on the T lymphocyte repertoire in the mouse: analysis from a TCR point of view

Ingeborg Tinhofer-Keilholz: Mutational profiling using next-generation sequencing reveals distinct molecular mechanisms of radioresistance in HPV+ and HPV- head and neck cancer.

Piotr Widłak: Signature of serum proteome in patients exposed to ionizing radiation.

Karol Jelonek: Characterization of exosomes released from irradiated cells.

Andrzej Swinarew: MALDI-ToF and UHPLC in peptide and protein characterization - potential application in radiation research.

Bioinformatics

Jacek Koronacki: Discovering interdependencies of features in disease-related genomic data.

Jan Komorowski: Genes causing many cancers are located near tumor-mutated motifs for the CTCF and other transcription factors.

Marek Kimmel: Modeling lung cancer drivers based on the cancer genome atlas data.

Klaus H. Maier-Hein: Data-driven oncologic image analysis.

David P. Kreil: Power and limitations of RNA-Seq: findings from the SEQC consortium.

Roles of Noncoding RNAs

Gunter Meister: RNA-binding proteins as regulators of coding and non-coding gene expression.

Joanna Rzeszowska-Wolny: X-ray induced changes in RNA interference suggest independent modulation of mRNA and protein levels.

Joost Kluiver: Non-coding RNAs as oncogenic components of the MYC regulatory network in Burkitt lymphoma.

Gabor Szabo: DNA/RNA hybrids in the chromatin.

Mitochondrial Channels and Reactive Oxygen Species

Adam Szewczyk: What we don't know about mitochondrial potassium channels.

Krzysztof Dołowy: Ion channels in mitochondria: the matter of life and death.

Piotr Bednarczyk: Regulation of mitochondrial potassium channels.

Przemysław Borys: Estimation of the maximum flux through ion channel.

Magdalena Skonieczna: Inhibition of the voltage-dependent anion channels and their influence on cell functioning.

Jakub Hanus: Induction of necroptosis by oxidative stress in retinal pigment epithelial cells.

Katarzyna Szołtysek: Role of reactive oxygen species in crosstalk between UV and cytokine activated signaling.

Szymon Borek: Modification in modern tools for cell based assays including mitochondria and reactive oxygen species analysis.

XXth Gliwice Scientific Meetings 2016

18-19.11.2016

Crosstalk between the Heat Shock Response and Cancer

Gabrielle Multhoff: Heat shock response and NK mediated immunity in cancer therapy.

Lea Sistonen: Transcriptional re-programming of genes in cell stress and cancer - synergistic and opposite effects of heat shock factors, HSFs

Michael Y. Sherman: Targeting Hsp70 in cancer.

Maciej Żylicz: Chaperone mediated cancer cell chemoresistance.

Wiesława Widłak: HSF1 contribution to cancer cell phenotype.

Dorota Ścieglińska: HSPA2 - cytoprotective or regulatory protein?

Molecular and Numerical Gears of Circadian Clocks

Hans Reinke: Crosstalk of stress response pathways and the circadian clock in mammals.

ncis Lévi: Personalising cancer treatments through systems chronotherapeutics.

Elham Farshaid: The circadian clock proteins BMAL1 and CLOCKcontrol G2/M cell cycle transition.

Celine Feillet: The circadian clock-cell cycle connection.

Joanna Rzeszowska-Wolny: Reactive oxygen species and circadian rhythms.

Krzysztof Psium-Maksymowicz: Platform for remote testing and analyzing of biomedical data.

Marek Zurawski: Microscale thermophoresis: quantitative interaction analysis and beyond.

Chromatin Structure and Modulation of Transcription session co-organized by EACR members

Marcelo Alda: WWOX, the FRA16D chromosomal fragile site gene, at the crossroads of cancer and CNS pathology.

Rami Aqeilan: Role of tumour suppressor WWOX, the gene product of common fragile site FRA16D, in human diseases.

Andrzej Bednarek: The role of Notch signaling pathway in regulation of gene expression in cancer.

Sergey Razin: Self-organization of a chromatin fiber.

Regulatory RNA

Angel Barco: Interplay of transcriptional and epigenetic mechanisms in neuronal activity-driven gene expression.

Włodzimierz Krzyżosiak: Small RNAs in Triplet Repeat Diseases. (25’)

Krzysztof Chylinski: Sharpening the knives of CRISPR/Cas9.

Marek Los: MicroRNAs, regulators of cell proliferation and (cancer) cell stemless - miR-301a as an example.

Krzysztof Fujarewicz: A model for the effects of ionizing radiation on microRNA-mediated regulation of mRNA levels in cells.

Witold Konopka: Neuronal RNA processing in memory formation.

Biomaterials and Medical Biotechnology

Mehrdad Rafat: Artificial corneas, clinical trials - example of a successful bioengineering of an organ.

Judith Staerk: Lamin B1-mediated gene regulation during human hematopoiesis.

Emilia Wiechec: Rate-limiting energy enzyme in carbohydrate metabolism PFKFB3 - differential expression iniPS and in cancer stem cells.

Jacek Kubiak: Preventive measures against chronic rejection of heart transplants.

Anna Mielańczyk: Polymethacrylates as drug carriers - structure vs cell viability in MCF-7 cell lines.

Lecturers that contributed to Gliwice Scientific Meetings in years 1997-2016

Abdollahi, Amir German Cancer Research Center, Heidelberg

Albini, Adriana IRCCS MutiMedica, Milan

Aldaz, Marcelo University of Texas, MD Anderson Cancer Center, Houston

Amos, William Cambridge University, Cambridge

Antosiewicz, Jędrzej Medical University of Gdansk, Gdańsk

Aqeilan, Rami Hebrew University, Jerusalem

Baer-Dubowska, Wanda Poznan University of Medical Sciences, Poznań

Barańska, Jolanta Marceli Nencki Institute of Experimental Biology, PAS, Warszawa

Barcellos-Hoff, Mary Helen New York University School of Medicine, New York

Barciszewski, Jan Institute of Bioorganic Chemistry, PAS, Poznań

Barco, Angel Miguel Hernandez University, Alicante

Bartnik, Ewa University of Warsaw, Warszawa

Bartoszek, Agnieszka Medical University of Gdansk, Gdańsk

Bathen, Tone F. Norwegian University of Science and Technology, Trondheim

Bednarczyk, Piotr Warsaw University of Life Sciences, Warszawa

Bednarek, Andrzej Medical University of Lodz, Łódź

Bielecki Stanisław Technical University of Lodz, Łódź

Blaese, Marcel University of Tubingen, Tubingen

Bobek-Billewicz, Barbara MSC Cancer Center and Institute of Oncology, Gliwice

Borys, Przemysław Silesian University of Technology, Gliwice

Boyd, Marie Cancer Research UK, Glasgow

Brammer, Ingo University of Hamburg, Hamburg

Brasier, Allan R. University of Texas, Medical Branch, Galveston

Bretschneider, Till Warwick Systems Biology Centre, Coventry

Broberg-Palmgren, Karin Karolinska Institutet, Lund

Brown, Karen University of Leicester, Leicester

Brzeski, Jan Copernicus Science Center, Warszawa

Budach, Volker Charite University, Berlin

Bujnicki, Janusz M. International Institute of Molecular and Cellular Biology, Warszawa

Butkiewicz, Dorota MSC Cancer Center and Institute of Oncology, Gliwice

Campos-Lima, Pedro Laval University, Quebec

Candeias, Serge CEA, Grenoble

Canzian, Federico German Cancer Research Center, Heidelberg

Capper, David German Cancer Research Center, Heidelberg

Cebrat, Stanisław University of Wroclaw, Wrocław

Cebulska-Wasilewska, Antonina Institute of Nuclear Physics, PAS, Kraków

Chekhun, Vasyl F. Institute of Experimental Pathology and Oncology, Kiev

Chlichlia, Katerina Democritus University of Thrace, Alexandroupolis

Chorąży, Mieczysław MSC Cancer Center and Institute of Oncology, Gliwice

Chovanec, Miroslaw Cancer Research Institute, Bratislava

Christoffersen, Thoralf University of Oslo, Oslo

Chyliński, Krzysztof CRISP-Lab, VBCF ProTech, Vienna

Conrad, Charles University of Texas, MD Anderson Cancer Center, Houston

Crebelli Riccardo Istituto Supriore di Sanita, Rome

Czerwiński, Marcin Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław

Czyż, Małgorzata Medical University of Lodz, Łódź

Dadlez, Michał Institute of Biochemistry and Biophysics, PAS, Warszawa

Dąbrowski, Michał Marceli Nencki Institute of Experimental Biology, PAS, Warszawa

Delaunay, Franck Universite Nice Sophia Antipolis, Nice

Dinkova-Kostova, Albena University of Dundee, Dundee

Djamgoz, Mustafa B.A. Imperial College, London

Dolezal Martin Charles University, Prague

Dołowy, Krzysztof Warsaw University of Life Sciences, Warszawa

Domagala, Wenancjusz Pomeranian Medical University, Szczecin

Drobot, Ludmila B. Palladin Institute of Biochemistry, NASU, Kyiv

Drouin, Regen Laval University, Quebec

Dusińska, Maria Norwegian Institute for Air Research, Kjeller

Dux, Kazimierz MSC Cancer Center and Institute of Oncology, Warszawa

Dziadkowiec, Dorota University of Wroclaw, Wrocław

Erenpreisa, Katrina University of Riga, Riga

Fajkus, Jiri Institute of Biophysics, Brno

Figlerowicz, Marek Institute of Bioorganic Chemistry, PAS, Poznań

Filipski, Jan Institute of Jacques Monod, Paris

Fiszer-Kierzkowska, Anna MSC Cancer Center and Institute of Oncology, Gliwice

Farshaid, Elham Erasmus Medical Center, Rotterdam

Feillet, Celine Universite Nice Sophia Antipolis, Nice

Formanowicz, Piotr Poznan University of Technology, Poznań

Försti, Asta German Cancer Research Center, Heidelberg

Fujarewicz, Krzysztof Silesian University of Technology, Gliwice

Gamian Andrzej Medical University of Wroclaw, Wrocław

Garrard, William T. UT Southwestern Medical Center, Dallas

Gasteiger, Johann Computer-Chemie-Centre, Erlangen-Nurnberg

Gaudray, Patrick CNRS, Nice

Getto Philippe Technische Universitat Dresden, Dresden

Giefing, Maciej Institute of Human Genetics, PAS, Poznań

Giel-Pietraszyk, Małgorzata Institute of Bioorganic Chemistry, PAS, Poznań

Giphart-Gassler, Micheline Leiden University Medical Center, Leiden

Gniazdowski, Marek Medical University of Lodz, Łódź

Goc, Anna Nicolaus Copernicus University, Toruń

Godzik, Adam Joint Center for Structural Genomics, La Jolla

Goedecke, Wolfgang University of Essen, Essen

Goffeau, André Institut des Sciences de la Vie, Louvain-la-Neuve

Golebiewska Anna Luxembourg Institute of Health, Luxembourg

Goncharova, Rose Institute of Genetics and Cytology, Minsk

Graham, Trevor Queen Mary University of London, London

Grąziewicz, Maria Institute of Biochemistry and Biophysics, PAS, Warszawa

Grynkiewicz, Grzegorz Pharmaceutical Research Institute, Warszawa

Guzdek Amalia Jagiellonian University, Kraków

Grzybowska, Ewa MSC Cancer Center and Institute of Oncology, Gliwice

Grzywna, Zbigniew Silesian University of Technology, Gliwice

Hamann, Ute German Cancer Research Center, Heidelberg

Hancock, Ronald Laval University Cancer Research Centre, Québec

Handkiewicz-Junak, Daria MSC Cancer Center and Institute of Oncology, Gliwice

Hannan, Ross Research Division, Peter MacCallum Cancer Centre, Melbourne

Hansen, Lise L. University of Aarhus, Aarhus

Hanus, Jakub Tulane University, New Orleans

Hartman, Mariusz Medical University of Lodz, Łódź

Hemminki, Kari German Cancer Research Center, Heidelberg

Henkel, Corinna Ruhr University, Bochum

Hennig, Jacek Institute of Biochemistry and Biophysics, PAS, Warszawa

Hennig, Wolfgang Shanghai Institutes for Biological Sciences, Shanghai

Hesse, Holger Max-Planck-Institute, Golm

Hibner, Urszula University of Montpellier, Montpellier

Hoheisel, Jörg German Cancer Research Center, Heidelberg

Hulmes, David Institut de Biologie et Chimie des Protéines, CNRS, Lyon

Iżycki, Dariusz Poznan University of Medical Sciences, Poznań

Jachymek, Wojciech Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław

Jakimowicz, Dagmara Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław

Jakóbisiak, Marek Medical University of Warsaw, Warszawa

Jałoszyński, Paweł Institute of Human Genetics, PAS, Poznań

Janiak, Marek K. Military Institute of Hygiene and Epidemiology, Warszawa

Janik, Przemysław MSC Cancer Center and Institute of Oncology, Warszawa

Janiszewska, Joanna Institute of Human Genetics, PAS, Poznań

Jarząb, Barbara MSC Cancer Center and Institute of Oncology, Gliwice

Jarząb, Michał MSC Cancer Center and Institute of Oncology, Gliwice

Jażdżewski, Krystian Comprehensive Cancer Center, Columbus

Jelonek, Karol MSC Cancer Center and Institute of Oncology, Gliwice

Jerzmanowski, Andrzej Institute of Biochemistry and Biophysics, PAS, Warszawa

Jerzy Ostrowski MSC Cancer Center and Institute of Oncology, Warszawa

Jurczak, Wojciech Jagiellonian University, Kraków

Jurka, Jerzy Genetic Information Research Institute, Mountain View

Kaminska, Bozena Marceli Nencki Institute of Experimental Biology, PAS, Warszawa

Kanthou, Chryso Sheffield University, Sheffield

Kasten-Pisula, Ulla Eppendorf University, Hamburg

Kieda, Claudine Centre for Molecular Biophysics, UPR 4301 CNRS, Orleans

Kimmel, Marek Rice University, Houston, Silesian University of Technology, Gliwice

Kluiver, Joost University of Groningen, Groningen

Knappskog, Stian University of Bergen, Bergen

Komorowski, Jan Uppsala University, Uppsala

Konieczny, Igor University of Gdansk, Gdańsk

Konopa, Jerzy Gdansk University of Technology, Gdańsk

Konopka, Witold German Cancer Research Center, Heidelberg

Kool, Marcel German Cancer Research Center, Heidelberg

Kopitar, Natasha Josef Stefan Institute, Ljubljana

Koronacki, Jacek Institute of Computer Science, PAS, Warszawa

Korzeniewski Bernard Jagiellonian University, Kraków

Kowalczuk, Marek Centre of Polymer and Carbon Materials, PAS, Zabrze

Kozomara, Ana University of Manchester, Manchestr

Kreil, David P. University of Natural Resources and Life Sciences, Vienna

Kreuzinger, Norbert Vienna University of Technology, Vienna

Kruszewski, Marcin Institute Nuclear Chemistry and Technology, Warszawa

Krzysko Krystiana University of Warsaw, Warszawa

Krzyżosiak, Włodzimierz Institute of Bioorganic Chemistry, PAS, Poznań

Kubiak, Jacek CNRS, Paris

Kubicarowa, T. Institute of Biophysics, Brno

Kujawski, Maciej Institute of Human Genetics, PAS, Poznań

Kulma Anna University of Wroclaw, Wrocław

Kumala, Sławomir McGill University, Montreal

Kupryjańczyk, Jolanta MSC Cancer Center and Institute of Oncology, Warszawa

Kurzyńska-Kokorniak, Anna Institute of Bioorganic Chemistry, PAS, Poznań

Lachowicz, Mirosław University of Warsaw, Warszawa

Larsson, Catharina Pharmacology Biovitrum, Stockholm

Leluk, Jacek University of Zielona Góra, Zielona Góra

Leppek, Kathrin German Cancer Research Center, Heidelberg

Lesyng, Bogdan University of Warsaw, Warszawa

Lévi, Francis Warwick University Medical School, Coventry

Lichtarge, Olivier Baylor College of Medicine, Houston

Limon, Janusz Medical University of Gdansk, Gdańsk

Lipniacki, Tomasz Institute of Fundamental Technological Research, PAS, Warszawa

Lityńska, Anna Jagiellonian University, Kraków

Los, Marek Linkoping University, Linkoping

Lotfi, Kourosh Linkoping University, Linkoping

Lubiński, Jan Pomeranian Medical University, Szczecin

Lukanova, Annekatrin German Cancer Research Center, Heidelberg

Łuczkiewicz, Aneta Gdansk University of Technology, Gdańsk

Łukaszewicz, Marcin University of Wroclaw, Wrocław

Macht, Marcus Bruker Daltonics, Bremen

Madden, Timothy University of Texas MD Anderson Cancer Center, Houston

Magdziarz Tomasz University of Silesia, Katowice

Maier-Hein, Klaus H. German Cancer Research Center, Heidelberg

Mairs, Rob UK Beatson Laboratories, Glasgow

Majchrzak, Henryk Silesian Medical University, Katowice

Majka, Jerzy Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław

Makałowska, Izabela Adam Mickiewicz University, Poznań

Makałowski, Wojciech Pennsylvania State University, University Park

Malanga, Maria Institute for Veterinary Pharmacology and Toxicology, Zurich

Małecki, Maciej MSC Cancer Center and Institute of Oncology, Warszawa

Mansoor, Ahmed University of Miami, Miami

Marciniak-Czochra, Anna University of Heidelberg, Heidelberg

Marcon, Francesca Istituto Supriore di Sanita, Rome

Marczak, Łukasz Institute of Bioorganic Chemistry, PAS, Poznań

Markiewicz, Ewa University of Wroclaw, Wrocław

Markiewicz, Wojciech Institute of Bioorganic Chemistry, PAS, Poznań

Martin Rachel Shimadzu Biotech Kratos Analytical

Marszałek, Jarosław University of Gdańsk, Gdańsk

Masny, Aleksander Institute of Biotechnology and Antibiotics, Warszawa

Matter, Jean-Marc University of Lausanne, Lausanne

McKay, Bruce C. Ottawa Hospital Research Institute, Ottawa

Meiss, Gregor Justus Liebig University, Giessen

Meister, Gunter Regensburg University, Regensburg

Meriç Pagano, Süreyya Namik Kemal University, Tekirdag

Mielanczyk, Anna Silesian University of Technology, Gliwice

Mier, Walter Universitätsklinikum Heidelberg, Heidelberg

Milcarz, Magdalena University of Wroclaw, Wrocław

Mirowski, Marek Medical University of Lodz, Łódź

Mosieniak, Grażyna Marceli Nencki Institute of Experimental Biology, PAS, Warszawa

Mothersill, Carmel McMaster University, Hamilton

Mouscadet, Jean Francois Ecole Normale Supérieure de Cachan CNRS, Cachan

Motykiewicz, Grażyna MSC Cancer Center and Institute of Oncology, Gliwice

Mozrzymas, Jerzy Wrocław Medical University, Wrocław

Mullenders, Leon H. Leiden University, Leiden

Muller-Rober, Bernd University of Potsdam, Potsdam

Multhoff, Gabrielle Technical University of Munich, Munich

Murphy, James Institute of Technology Sligo, Ballinode Sligo

Mycielska, Maria Imperial College, London

Nakielski, Jerzy University of Silesia, Katowice

Nauman, Paweł Institute of Psychiatry and Neurology, Warszawa

Niedźwiedź, Wojciech Oxford University, Oxford

Nino, Ewa INSERM, Curie University, Paris

Nino, Jacques Ecole Normale Superieure, Paris

Noteborn, Mathieu H. Biological Chemistry, Leiden University, Leiden

Obolenskaya, Maria Institute of Molecular Biology and Genetics, NAS, Kiev

Oliński, Ryszard Nicolaus Copernicus University, Bydgoszcz

Ortmann, Elisabeth University of Vienna, Vienna

Ostrowski, Jerzy MSC Cancer Center and Institute of Oncology, Warszawa

Ott, Sascha University of Warwick, Coventry

Palyvoda, Olena Wayne State University, Detroit

Pavanello, Sofia University of Padova, Padova

Pawlak, Andrzej Institute of Human Genetics, Poznań

Pawlas, Natalia Institute of Occupational Medicine and Environmental Health, Sosnowiec

Perkins, Neil D. Newcastle University, Newcastle

Philmonienko, Vlada Institute of Experimental Medicine, Prague

Pilc, Andrzej Institute of Pharmacology, PAS, Kraków

Pingoud, Alfred Justus Liebig University, Giessen

Pirsel, Miroslav Cancer Research Institute, SAS, Bratislava

Płucienniczak, Andrzej Institute of Biotechnology and Antibiotics, Warszawa

Polanski, Andrzej Silesian University of Technology, Gliwice

Polanski, Jaroslaw University of Silesia, Katowice

Polańska, Joanna Silesian University of Technology, Gliwice

Poleszczuk, Jan University of Warsaw, Warszawa

Priebe, Waldemar University of Texas, MD Anderson Cancer Center, Houston

Prise, Kevin Gray Cancer Institute, Northwood

Psiuk-Maksymowicz, Krzysztof Silesian University of Technology, Gliwice

Rabakon Nadzeya Institute of Genetics and Cytology, Minsk

Puszyński, Krzysztof Silesian University of Technology, Gliwice

Radzikowski, Czesław Institute of Immunology and Experimental Therapy, Wrocław

Rafat, Mehrdad Linköping University, Linköping

Ratuszna, Alicja University of Silesia, Katowice

Razin, Sergey Institute of Gene Biology, RAS, Moscow

Reinke, Hans Medical University, Dusseldorf

Rokita, Hanna Jagiellonian University, Kraków

Rőmpp, Andreas Justus Liebig University, Giessen

Rothkamm, Kai University of Saar, Homburg

Rubi, Miguel Universitat de Barcelona, Barcelona

Rybaczek Dorota Universityof Lodz, Lódź

Rubi, Miquel Universitat de Barcelona, Barcelona

Rusin, Aleksandra MSC Cancer Center and Institute of Oncology, Gliwice

Rusin, Marek MSC Cancer Center and Institute of Oncology, Gliwice

Rzepecki, Ryszard University of Wroclaw, Wrocław

Rzeszowska-Wolny, Joanna Silesian University of Technology, Gliwice

Sáfrány, Geza National Research Institute for Radiobiology and Radiohygiene, Budapest

Sandness, Dagny University of Oslo, Oslo

Sąsiadek, Maria Medical University of Wroclaw, Wrocław

Schieck, Alexa Universitätsklinikum Heidelberg, Heidelberg

Schluter, Urte Riso National Laboratory, Copenhagen

Schueltke, Elisabeth Albert Ludwigs University, Freiburg

Seymour, Colin McMaster University, Hamilton

Sfakianakis, Nikolaos University of Mainz, Mainz

Sherman Michael Y. Boston University School of Medicine, Boston

Sherthan, Harry Institute of Radiobiology, Muenhen

Shieck, Valentin Institute of Molecular Biology, RAS, Moscov

Sidorenko, Svetlana Institute of Experimental Pathology and Oncology, Kiev

Sidorik, Lyudmila Institute of Molecular Biology and Genetics, Kiev

Siedlecki, Janusz MSC Cancer Center and Institute of Oncology, Warszawa

Sieroń, Aleksander Medical University of Silesia, Katowice

Sierra, Angels Bellvitge Biomedical Research Institute, IDIBELL, Barcelona

Siewiński, Maciej Medical University of Wroclaw, Wrocław

Sikora, Ewa Marceli Nencki Institute of Experimental Biology, Warszawa

Silberring, Jerzy AGH University of Science and Technology, Kraków

Simard, Martin Laval University, Quebec

Simek, Krzysztof Silesian University of Technology, Gliwice

Sirko, Agnieszka Institute of Biochemistry and Biophysics, PAS, Warszawa

Sistonen, Lea Abo Academi University, Turku

Sjakste, Nicolai University of Latvia, Riga

Składanowski, Andrzej M. Medical University of Gdańsk, Gdańsk

Skonieczna, Magdalena Silesian University of Technology, Gliwice

Skrzydlewska, Ewa Medical University of Bialystok, Białystok

Skrzypczak, Magdalena MSC Cancer Center and Institute of Oncology, Warszawa

Smolyakova, Raisa Alexandrov Research Institute of Oncology and Medical Radiology, Minsk

Smołka, Bogdan Silesian University of Technology, Gliwice

Staerk, Judith University of Oslo, Oslo

Staroń, Krzysztof University of Warsaw, Warszawa

Steffen, Jan MSC Cancer Center and Institute of Oncology, Warsaw

Steinbrink, Sandra German Cancer Research Center, Heidelberg

Strätling, Wolf H. Eppendorf University, Hamburg

Student, Sebastian Silesian University of Technology, Gliwice

Stühmer, Walter Max-Planck Institute of Experimental Medicine, Göttingen

Svoboda, Petr Institute of Molecular Genetics, ASCR, Prague

Swinarew, Andrzej University of Silesia, Katowice

Sykorowa, Ewa Institute of Biophysics, Brno

Szabo, Gabor University of Debrecen, Debrecen

Szala, Stanisław MSC Cancer Center and Institute of Oncology, Gliwice

Szaumkessel, Marcin Institute of Human Genetics, PAS, Poznan

Szeja, Wiesław Silesian University of Technology, Gliwice

Szewczyk, Adam Marceli Nencki Institute of Experimental Biology, PAS, Warszawa

Szołtysek, Katarzyna MSC Cancer Center and Institute of Oncology, Gliwice

Szopa, Jan University of Wroclaw, Wrocław

Sztajer, Helena Technical University of Braunschweig, Braunschweig

Szumiel, Irena Institute Nuclear Chemistry and Technology, Warszawa

Szydło, Anna Medical University of Silesia, Katowice

Szyfter, Krzysztof Institute of Human Genetics, PAS, Poznań

Ścieglińska, Dorota MSC Cancer Center and Institute of Oncology, Gliwice

Świerniak, Andrzej Silesian University of Technology, Gliwice

Tarnawski, Rafał MSC Cancer Center and Institute of Oncology, Gliwice

Tavassoli, Mahvash King's College London, Guy's Hospital Campus, London

Teleman, Aurelio German Cancer Research Center, Heidelberg

Tinhofer-Keilholz, Ingeborg Charite University, Berlin

Tomiałojć, Ludwik University of Wroclaw, Wroclaw

Trott, Klaus-Rudiger Technical University of Munich, Munich

Tudek, Barbara Institute of Biochemistry and Biophysics, PAS, Warszawa

Ugorski, Maciej Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław

Unold, Olgierd Technical University of Wroclaw, Wrocław

Urbanek, Ksymena Medical University of Silesia, Katowice

Valiokas, Ramunas Center for Physical Sciences and Technology, Vilnius

Van den Berg, Anke University of Groningen, Groningen

Van den Berghe, Wim University Antwerp, Antwerp

Von Mikecz, Anna Heinrich Heine University, Dusseldorf

Walczak, Beata University of Silesia, Katowice

Walewski, Jan MSC Cancer Center and Institute of Oncology, Warsaw

Wcisło, Gabriel Military Medical Institute, Warszawa

Wandzik, Ilona Silesian University of Technology, Gliwice

Wegrowski, Yanusz CNRS MEDyC, Reims University, Reims

Węgrzyn, Grzegorz Gdańsk University of Technology, Gdańsk

Wesierski-Gadek, Józefa Medical University of Vienna, Vienna

White, Steven University of California, Irvine

Wideł, Maria Silesian University of Technology, Gliwice

Widłak, Piotr MSC Cancer Center and Institute of Oncology, Gliwice

Widłak, Wiesława MSC Cancer Center and Institute of Oncology, Gliwice

Wiecheć, Emilia Linkoping University, Linkoping

Wiemann, Stefan German Cancer Research Center, Heidelberg

Wierzbicka, Małgorzata Institute of Human Genetics, PAS, Poznań

Wilczyński, Grzegorz University of Wroclaw, Wrocław

Wilson, Gareth Cancer Research UK, London Research Institute London, London

Winkler, Frank German Cancer Research Center, Heidelberg

Wiśniewski, Jacek R. Max-Planck-Institute for Biochemistry, Martinsried

Wojdyła, Tomasz Silesian University of Technology, Gliwice

Wójcik, Andrzej Stockholms Universitet, Stockholm

Wróbel, Magdalena University of Wrocław, Wrocław

Wyszko, Eliza Institute of Bioorganic Chemistry, PAS, Poznań

Youdinkova, Elena Institute of Gene Biology, RAS, Moscow

Xiao-Feng, Sun Linkoping University, Linkoping

Xue, Ding University of Colorado, Boulder

Zakrzewska, Jolanta Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław

Zanchetta, Luciene Institute of Technology SligoAsh Lane, Sligo

Zdzienicka, Margaret University of Leiden, Leiden

Ziembińska-Buczyńska, Aleksandra Silesian University of Technology, Gliwice

Zimny, Janusz A. Plant Breeding and Aclimatization Institute, Radzików

Żurawski, Marek NonoTemper Technologies, Munich

Żylicz, Maciej International Institute of Molecular and Cellular Biology, Warszawa

Best Poster Presentations Awards of the Association for the Support of Cancer Research

2016 - Ewa Marek, Anna Lalik, Roman Jaksik: Stability of reference gene expression in cells exposed to stressing factors

2015 - Kristine Salmina, Anda Huna, Jekaterina Erenpreisa: Role of autophagy in survival of embryonal carcinoma cells treated with etoposide

2014 - Jolanta Guz, Daniel Gackowski, Marek Foksinski, Rafal Rozalski, Tomasz Dziaman, Ewelina Zarakowska, Anna Szpila, Ryszard Olinski: 5-methylcytosine, 5-hydroxymethylcytosine and 5-hydroxy-methyluracil in human leukocytes and sperm as epigenetic marks – comparison of the absolute level

2013 - Jadwiga Pietkiewicz, Urszula Bazylińska, Joanna Rossowska, Anna Choromańska, Andrzej Gamian, Kazimiera Anna Wilk: Biocompatibility of nanoparticles loaded with photosensibilizers for practical use in support of anticancer therapy

2012 - Karol Ruszel, Paweł Kowalczyk, Agnieszka Maciejewska, Jarosław Kuśmierek: The effect of chloracetaldehyde on M13MP18 phage replicated in Escherichia coli JM 105 ALKB strain

2011 - Małgorzata Sekuła, Katarzyna Miękus, Marcin Majka: SDF-1/ITAC – CXCR7 axis in biology of cervical carcinoma

2010 - Marek Żurawski: Generation of induced pluripotent stem cells from human mesenchymal and hematopoietic cells

2009 - Andriy Slonchak, Agata Chwieduk, Jhoanna Rzerzowska-Wolny, Maria Obolenska: Regulation of the human glutathione s-transferase P1 gene transcription

2008 - Wojciech Pigłowski, Piotr Filipczak, Zdzisław Krawczyk, Dorota Ścieglińska: Analysis of intracellular localization of the human HspA2 protein in cancer cells

2007 - Paweł Kowalczyk, Jolanta Jaworek, Michalina Kot, Beata Sokołowska, Aleksandra Bieleń, Beata Janowska, Jarosław M. Cieśla, Grzegorz Szparecki, Benita Sadom, Barbara Tudek: Inflammation increases oxidative DNA damage repair and stimulates preneoplastic changes in colons of newborn rats

2006 - Subbareddy Maddika, Emilia Wiechec, Lise-Lotte Hansen, Marek Los: Pro-apoptotic role of PI3-K/AKT pathway during apoptosis induced by selected anti-cancer drugs

2005 - Halina Waś, Tomasz Cichoń, Anna Ratajska, Anna Grochot, Barbara Węgiel, Agnieszka Łoboda, Agnieszka Jaźwa, Józef Dulak, Alicja Józkowicz: Effect of heme oxygenase-1 on proliferation, viability and angiogenic potential of melanoma cells in mice

2004 - Magdalena Kalinowska, Wojciech Garncarz, Monika Pietrowska, Piotr Widłak: Regulation of the human apoptotic nuclease endonuclease G

2003 - Ewa Ciesielska, Kazimierz Studzian, Elżbieta Żyner, Justyn Ochocki, Leszek Szmigiero: Cisplatin with aminoflavone wings as an improved apoptosis inducer of cancer cells

2002 - Wiesława Widłak, Witold Konopka, Anna Zborek, Dorota Ścieglińska, Zdzisław Krawczyk: GFP fluorescence in somatic cells of transgenic mice containing EGFP reporter gene under the control of the rat testis-specific hst70 gene promoter

2001 - Paweł Kowalczyk, Jarosław M. Cieśla, Maria-Anna Grąziewicz, Jarosław T. Kuśmierek, Barbara Tudek: DNA damage in P53 gene by chloroacetaldehyde and trans-4-hydroxy-2-nonenal

2000 - Olena Palyvoda, Piotr Widłak: Characterization of DFF40/CAD endonuclease - mediated pathway of apoptotic chromatin condensation

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