Gianluca Iacobellis MD PhD - Physicians Database Loginphydatabase.med.miami.edu/documents/cv/Iacobellis.Gianluca_95878...Dr Iacobellis CV December 2016 1 Curriculum Vitae Gianluca

Dr Iacobellis CV December 2016

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Curriculum Vitae

Gianluca Iacobellis MD PhD

� PERSONAL

Name Gianluca Iacobellis

Date and place of birth May 6, 1970, Rome, Italy

Languages English, Italian, Spanish

Business Address 1400 NW 10th, Avenue, suite 804, Miami, FL 33136

Tel 305 243 6249 FAX 305 243 9487

Email: [email protected]

Current Academic Rank Professor of Clinical Medicine, Division of Endocrinology,

Diabetes and Metabolism, Department of Medicine , University

of Miami, Miller School of Medicine, Miami, FL

Director of the University of Miami Hospital (UMH) Diabetes

Service, University of Miami, FL

Director of the Jackson Memorial Hospital Diabetes Clinic,

� EDUCATION

03/2001-03/2004 PhD, Endocrinological & Metabolic Science,

“University of Rome “La Sapienza”, Rome Italy

09/1995-01/2001 Specialist in Endocrinology and Metabolic Disorders,

University of Rome “La Sapienza”, Rome, Italy

09/1988- 07/1994 MD degree, Medicine, “University of Rome “La Sapienza”,

Rome, Italy

09/1983-07/1988 High School Diploma, Maturita’ Classica, Liceo Giulio Cesare,

Rome Italy


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� MEDICAL LICENSES, CERTIFICATION

08/2015-present Florida Medical License ME125273

08/2010-8/2016 Florida Medical Faculty Certificate MFC1663

2007 –2010 College of Physicians and Surgeons of Ontario (CPSO) License

Active Member, (Registration # 83759), Canada

1995 -present Medical License Certification

College of Italian Physicians and Surgeons in Rome Italy (Active

Member Registration # M 46563)

� ACADEMIC APPOINTMENTS

2013-present Professor of Clinical Medicine, Division of Endocrinology, Diabetes and

Metabolism, University of Miami, Miller School of Medicine, USA

2010-2013 Associate Professor of Clinical Medicine, Division of Endocrinology,

Diabetes and Metabolism, University of Miami, USA

2006-2010 Associate Professor of Endocrinology Department of Medicine,

McMaster University, Hamilton, ON, Canada

� FELLOWSHIPS

09/2005 – 09/2006 Clinical Fellowship Cardiovascular Obesity Research and Management

Department of Medicine, McMaster University, Hamilton, ON, Canada

Supervisor: Prof. Arya M Sharma

01/2004 – 05/2005 Clinical Research Fellowship, Endocrinology and Clinical Nutrition, Centre

for Human, Nutrition, University of Texas, Southwestern Medical Centre

of Dallas, Dallas, Texas, USA Supervisor: Prof. Scott M Grundy

3/1999- 6/1999 Research Fellowship, Centrum for Metabolism & Endocrinology,

Karolinska Institutet, Stockholm, Sweden, Supervisor: Prof. Peter Arner


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� INTERNSHIPS

07/2005–07/2006 Post-graduate Internship, Endocrinology and Metabolism, McMaster

University, Hamilton, ON, Canada Supervisor: Prof. Hertzel Gerstein

03/2001 – 03/2004 Post-graduate Internship, Endocrinology and Metabolic Disorders,


09/1995 – 12/2000 Residency, Endocrinology, Diabetology and Metabolic Disorders,


07/1994 – 07/1995 Post-graduate Internship, General Internal Medicine, University of Rome

“La Sapienza”, Rome, Italy

� HOSPITAL APPOINTMENTS

2013-present Director of the University of Miami Hospital (UMH) Diabetes Service

University of Miami, FL

2010-present Director of the Ambulatory Clinical Care (ACC) Diabetes Clinic, Jackson

Memorial Hospital, University of Miami, FL

2008 - 2010 Director of the Bariatric Endocrinology Service

St. Joseph’s Hospital, Hamilton, ON, Canada

2008 -2010 Consultant Endocrinologist, Centre of Excellence for Bariatric Surgery, St.

Joseph’s Hospital, McMaster University, Hamilton, ON, Canada

2006- 2010 Responsible Endocrinology-Diabetes Out-Patient Service St. Joseph’s

Hospital, McMaster University, Hamilton, ON, Canada

� ADMINISTRATIVE EXPERIENCES

2013-present Director of the University of Miami Hospital (UMH) Diabetes Service

University of Miami, FL

2010-present Director of the Ambulatory Clinical Care (ACC) Diabetes Clinic, Jackson

Memorial Hospital, University of Miami, FL

2008 - 2010 Director of the Bariatric Endocrinology Service

St. Joseph’s Hospital, Hamilton, ON, Canada


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� PUBLICATIONS

Current h-index: 35

Citations: 4871 (source Scopus)

Journal Articles

1. Iacobellis G, Mohseni M, Bianco S, Banga P. Liraglutide causes large and rapid Epicardial Fat

reduction Obesity 2016 in press

2. Iacobellis G Epicardial fat: a new cardiovascular therapeutic target. Curr Opin Pharmacol.

2016 Feb 2;27:13-18

3. Lima-Martínez MM, Arrau C, Jerez S, Paoli M, González-Rivas JP, Nieto-Martínez R, Iacobellis

G. Relationship between the Finnish Diabetes Risk Score (FINDRISC), vitamin D levels, and

insulin resistance in obese subjects. Prim Care Diabetes. 2016: S1751-9918(16)30121-8

4. Petramala L, Iacobellis G, Carnevale R, Marinelli C, Zinnamosca L, Concistrè A, Galassi M,

Iannucci G, Lucia P, Pignatelli P, Ciardi A, Violi F, De Toma G, Letizia C. Enhanced Soluble Serum

CD40L and Serum P-Selectin Levels in Primary Aldosteronism. Horm Metab Res. 2016 Apr 21

5. Iacobellis G. Local and Systemic effects of the multifaceted Epicardial Adipose Tissue Depot.

Nature Reviews Endocrinology 2015;11:363-371

6. McAninich E, Bianco AC and Iacobellis G. Epicardial Adipose Tissue Has a Unique

Transcriptome that is Downregulated in Severe Coronary Artery Disease. Obesity, 2015;

23:1267-78.

7. Letizia, C, Iacobellis G. Leptin and adiponectin mRNA expression from the adipose tissue

surrounding the adrenal neoplasia. Journal of Clinical Endocrinology Metabolism 2015;

100:E101-4

8. Iacobellis G, Petramala L, Marinelli C, Calvieri C, Zinnamosca L, Concistrè A, Iannucci G, De

Toma G, Letizia C. Epicardial Fat Thickness and Primary Aldosteronism. Horm Metab Res.

2016 Apr;48(4):238-41


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9. Lima-Martínez MM, Paoli M, Rodney M, Balladares N, Contreras M, D'Marco L, Iacobellis G

Effect of sitagliptin on epicardial fat thickness in subjects with type 2 diabetes and obesity: a

pilot study. Endocrine. 2015 Aug 2

10. Elisha, Taleb S, Bernard, Iacobellis G, Rabasa-Lhoret R. Body composition and epicardial fat in

type 2 diabetes patients following insulin detemir versus insulin glargine initiation. Hormone

Metabolic Research 2015 Sep 4. [Epub ahead of print]

11. Iacobellis G. Is Epicardial Fat A Modifiable Cardiovascular Risk Factor and an Emerging

Therapeutic Target?" Circulation: Cardiovascular Imaging eLetter June 4, 2015 URL:

http://circimaging.ahajournals.org/cgi/eletters/8/3/e003156#3896

12. Iacobellis G et al Diseases of the Adrenal Glands Int J Endocrinology, 2015 Volume 2015,

Article ID 403521, http://dx.doi.org/10.1155/2015/403521

13. Corsi MM, Iacobellis G, Locati M. Interplay of Inflammation, Immunity, and Organ-Specific

Adiposity with Cardiovascular Risk. Mediators of Inflammation 2014:340847

14. Lima-Martínez MM, Campo E, Salazar J, Paoli M, Maldonado I, Acosta C, Rodney M, Contreras

M, Cabrera-Rego JO, Iacobellis G. Epicardial fat thickness as cardiovascular risk factor and

therapeutic target in patients with rheumatoid arthritis treated with biological and

nonbiological therapies. Arthritis. 2014; 782850

15. Iacobellis G, Xu C, Campo RE, De La Cruz-Munoz NF. Predictors of Short-Term Diabetes

Remission After Laparoscopic Roux-en-Y Gastric Bypass. Obes Surg. 2014 Nov 1

16. Kargi A, Iacobellis G Adipose tissue and adrenal glands: novel pathophysiological mechanisms

and clinical applications International Journal of Endocrinology, 2014:614074

17. Angeli F, Verdecchia and Iacobelllis G. Usefulness of QRS Voltage Correction by Body Mass

Index to Improve Electrocardiographic Detection of Left Ventricular Hypertrophy in Patients

with Systemic Hypertension. American Journal of Cardiology, 2014;114:427-32

18. Iacobellis G, Garcia A, Zaki M, Willens H, Epicardial Fat in Atrial Fibrillation and Heart Failure.

Hormones Metabolic Research 2014: 46: 1-4

19. Xu C, Iacobellis G. Perivascular Fat and its Role in Vascular Disease, Insulin Resistance and

Diabetes. Curr Cardiovasc Risk Rep 2014; 8: 370


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20. Iacobellis G, Mendez A, Diaz S, Goldberg R Increased Epicardial Fat and Plasma Leptin in

Type 1 Diabetes independently of Obesity Nutrition, Metabolism and Cardiovascular

Diseases 2014;24: 725-9

21. Iacobellis et al Epicardial Fat Thickness and Nonalcoholic Fatty Liver Disease in Obese

Subjects. Obesity 2014;22:332-6

22. Cabrera-Rego, Iacobellis G et al. Epicardial Fat Thickness correlates with Carotid Intima-

Media Thickness, Arterial stiffness and Cardiac Geometry in Children and Adolescents

Pediatric Cardiology 2014 ;35: 450-6

23. Iacobellis G. Epicardial adipose tissue in endocrine and metabolic diseases. Endocrine. 2013

44: 532-6

24. Iacobellis G et al. Brown fat expresses adiponectin in humans International Journal of

Endocrinology, 2013; 2013: 126571

25. Iacobellis G, Petramala L, Barbaro G, Kargi AY, Serra V, Zinnamosca L, Colangelo L, Marinelli

C, Ciardi A, De Toma G, Letizia C. Epicardial fat thickness and left ventricular mass in

subjects with adrenal incidentaloma. Endocrine. 2013;44: 532-6

26. Pierdomenico S. Iacobellis g. Metaanalysis of the Relation of Echocardiographic Epicardial

Adipose Tissue Thickness and the Metabolic Syndrome Am J Cardiol 2013;111:73-8

27. Lima-Martínez MM, Blandenier C, Iacobellis G Cut-off point of epicardial adipose tissue

thickness for predicting metabolic syndrome in Venezuelan population Endocrinol Nutr

2013 Jun 20. pii: S1575-0922

28. Lima-Martínez MM, Blandenier C, Iacobellis G. Epicardial adipose tissue: more than a simple

fat deposit?Endocrinol Nutr. 2012 Oct 29

29. Verdecchia P, Dagenais, Healey J, Gao P, Dans AL, Chazovae I, Binbrek AS, Iacobellis G, Yusuf

S, on behalf of Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint

Trial/Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with

cardiovascular Disease Investigators Blood Pressure and Other Determinants of New-Onset

Atrial Fibrillation in Patients at High Cardiovascular Risk in the ONTARGET/TRANSCEND

Studies Journal of Hypertension 2012: 30: 1004-1014

30. Iacobellis G, Bianco AB. Epicardial Adipose Tissue: emerging physiological, pathophysiological

and clinical features. Trends in Endocrinology and Metabolism. 2011; 22: 450-7


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31. Iacobellis G, Malavazos AE, Corsi MM Epicardial fat: from the biomolecular aspects to the

clinical practice. Int J Biochem Cell Biol. 2011;43: 1651-4

32. Ferrante E, Malavazos AE, Giavoli C, Ermetici F, Coman C, Bergamaschi S, Profka E, Briganti S,

Ronchi CL, Passeri E, Corbetta S, Lania AG, Spada A, Iacobellis G, Ambrosi B, Beck-Peccoz P

Epicardial fat thickness significantly decreases after short-term growth hormone (GH)

replacement therapy in adults with GH deficiency. Nutr Metab Cardiovasc Dis. 2013 ;23:459-

65

33. Torres C, Lima-Martínez MM, Rosa FJ, Guerra E, Paoli M, Iacobellis G, Rodney M, Romero-

Vecchione E, Luisa Saadtjian M, Zagala M, Rodney H. Epicardial adipose tissue and its

association to plasma adrenomedullin levels in patients with metabolic syndrome.

Endocrinol Nutr. 2011; 58: 401-8.

34. Rego JO, Iacobellis G, Sarmientos JC, Mustelier JV, Aquiles EW, Rodríguez VM, Rojas NA

Epicardial fat thickness correlates with ApoB/ApoA1 ratio, coronary calcium and carotid

intima media thickness in asymptomatic subjects. Int J Cardiol. 2011;151: 234-6

35. Iacobellis G, Iorio M, Napoli N, Cotesta D, Zinnamosca L, Marinelli C, Petramala L, Minisola S,

D'Erasmo E, Letizia C. Relation of adiponectin, visfatin and bone mineral density in patients

with metabolic syndrome. J Endocrinol Invest. 2011;34:e12-5

36. Iacobellis G, Lonn E, Lamy A, Singh N, Sharma AM Epicardial fat thickness and coronary

artery disease correlate independently of obesity. Int J Cardiol. 2011;146: 452-4

37. Iacobellis G, Malavazos AE Letter to Editor “Pericardial adipose tissue, atherosclerosis, and

cardiovascular disease risk factors: the Jackson heart study”. Diabetes Care 2010;33:e127

38. Iacobellis, Letizia C, et al. Adipokines and Cardiometabolic profile in Primary Aldosteronism.

Journal Clinical Endocrinology and Metabolism, 2010;95: 2391-8

39. Malavazos A, Iacobellis G, et al. Relation of Echocardiographic Epicardial Fat Thickness and

Myocardial Fat. Am J Cardiol. 2010; 105:1831-5.

40. Iacobellis G. Relation of Epicardial Fat Thickness to Right Ventricular Cavity Size in Obese

Subjects. American Journal of Cardiology 2009; 104: 1601-2.

41. Iacobellis G et al. Epicardial Adipose Tissue and Intracoronary Adrenomedullin levels in

Coronary Artery Disease. Hormone and Metabolic Research 2009;41:855-60

42. Iacobellis G, Willens H l. Echocardiographic epicardial fat: research and clinical applications.

Journal of American Society of Echocardiography 2009; 22:1311-9.


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43. Iacobellis G. Epicardial and Pericardial Fat: Close but very different. Obesity 2009:17; 625.

44. Iacobellis G et al. Intracoronary adiponectin levels rapidly increase after coronary

revascularization. International Journal of Cardiology 2009 Jan 26 (epub ahead of print)

45. Iacobellis G et al. Epicardial adipose tissue adiponectin expression is related to

intracoronary adiponectin levels. Hormone and Metabolic Research 2009; 41: 227-31.

46. Barbaro G and Iacobellis G. Metabolic syndrome associated with HIV and highly active

antiretroviral therapy. Curr Diab Rep. 2009; 9:37-42.

47. Iacobellis G, Willens H, Sharma AM. Threshold of high risk echocardiographic epicardial fat

thickness. Obesity 2008: 16; 887-92.

48. Iacobellis G, et al. Relation of epicardial fat and alanine aminotransferase in subjects with

increased visceral fat. Obesity 2008 16: 179-183.

49. Iacobellis G, Sharma AM, Wharton S, Singh N. Substantial changes in epicardial fat thickness

after weight loss in severely obese subjects. Obesity 2008; 16:1693-7.

50. Iacobellis G. Echocardiographic epicardial fat: A new tool in the white coat pocket. Nutr

Metab Cardiovasc Dis. 2008; 18: 519-22.

51. Iacobellis G et al. The double role of Epicardial Adipose Tissue as Pro and Anti-Inflammatory

Organ. Hormone and Metabolic Research 2008; 40:442-5.

52. Iacobellis G, Gerstein HC. Relationship of epicardial fat thickness and Impaired Fasting

Glucose. International Journal of Cardiology 2008; 128:424-6.

53. Iacobellis G, Gao YJ, Sharma AM. Does Cardiac and perivascular adipose tissue play a role in

atherosclerosis? Current Diabetes Reports 2008; 8: 20-4.

54. H Willens, , Goldberg R and Iacobellis G. Comparison of Epicardial and Pericardial Fat

Thickness Assessed by Echocardiography in non-Hispanic White and African-American Men.

Ethnicity & Diseases 2008; 18: 311-6.

55. Petramala L, Iacobellis G, et al Metabolic Alterations in Patients with Primary Aldosteronism

(PA): Role of Adipokines. High Blood Pressure & Cardiovascular Prevention 2008: 15; 239

56. Petramala L, Iacobellis G, et al Cardiac Modifications in Patients with Primary Aldosteronism

Before and After Specific Treatment High Blood Pressure & Cardiovascular Prevention 2008:

15; 273


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57. Iacobellis G et al. Small dense low density lipoprotein and c-reactive protein in obese

subjects with and without other criteria for the metabolic syndrome. Journal of Clinical

Lipidology 2007; 1: 599-604.

58. Iacobellis G et al Relationship of subepicardial adipose tissue with carotid intima media

thickness in HIV-infected patients Am J Cardiol 2007; 99: 1470-2.

59. Iacobellis G, AM Sharma Epicardial adipose tissue as new cardio-metabolic risk marker and

potential therapeutic target in the metabolic syndrome Current Pharmaceutical Design

2007:13: 2180-4.

60. Iacobellis G, G Barbaro Targeting the fat and fatty organ: perspective of novel therapeutic

strategies Current Pharmaceutical Design 2007: 13: 2146-7.

61. Iacobellis G et al. Epicardial adipose tissue is related to carotid intima media thickness and

visceral adiposity in HIV-infected patients with highly active antiretroviral therapy-

associated metabolic syndrome Current HIV Research 2007; 5:275-9.

62. Portincasa P, Moschetta A, Iacobellis G Non Alcoholic Fatty liver disease in the metabolic

syndrome Current Pharmaceutical Design 2007;13:2193-8.

63. Iacobellis G, AM Sharma. Obesity and the heart: redefinition of the relationship Obesity

Reviews 2007 8, 35–39.

64. Iacobellis G, Singh N, AM Sharma Cardiac adiposity and cardiovascular risk: potential role of

epicardial adipose tissue Curr Card Reviews 2007:13:11-4.

65. Iacobellis G, AM Sharma Hypertension in lean and obese individuals: An evenly or unevenly

dangerous condition. Nutr Metab Cardiovasc Dis. 2007; 17: 243-6.

66. Singh N, Arthur HM, Worster A, Iacobellis G, Sharma AM. Emergency department

equipment for obese patients: perceptions of adequacy J Adv Nurs 2007; 59:140-5.

67. Iacobellis G, Singh N, Leonetti F, AM Sharma Relationship of epicardial adipose tissue with

atrial dimensions and diastolic function in morbidly obese subjects International Journal of

Cardiology 2007;115:272-3.

68. Iacobellis G et al. Aminotransferase activity in morbid and uncomplicated obesity: Predictive

role of fasting insulin Nutr Metab Cardiovasc Dis. 2007; 17 442-7.


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69. Singh N, Singh H, Khanijoun HK, Iacobellis G. Echocardiographic assessment of epicardial

adipose tissue - a marker of visceral adiposity. Mcgill J Med. 2007; 10: 26-30.

70. Iacobellis and Sharma AM Treatment of obesity: a challenging task in Contrib Nephrol.

2006; 151:212-20.

71. Iacobellis G, CM Pond, AM Sharma Different weight of cardiac and general adiposity in

predicting left ventricle morphology Obesity 2006;14:1679-84.

72. Petrone, Iacobellis G Association of beta (2) adrenergic receptor polymorphisms and related

haplotypes with triglyceride and LDL-cholesterol levels Eur J Hum Genet.2006 14:94-100.

251.

73. S Balducci , Iacobellis G, L Parisi , N Di Biase, E Calandriello , F Leonetti , F Fallucca. Long-

term aerobic exercise training delays the onset of peripheral neuropathy in diabetic

patients. Journal of Diabetes and its complications 2006; 20:216-23.

74. Iacobellis G, Petrone A, Leonetti F, Buzzetti R. Increased Left Ventricular Mass in

Uncomplicated Obese Subjects Carrying the 276 G/G Single Nucleotide Polymorphism of the

Adiponectin Gene Obesity 2006; 14:368-372.

75. Iacobellis G, AM Sharma Adiposity of the heart Ann Intern Med. 2006; 145:554-5.

76. Iacobellis G, D Corradi, AM Sharma. Epicardial adipose tissue: anatomical, biomolecular and

clinical relation to the heart Nature Clinical Practice Cardiovascular Medicine 2005; 2: 536-

43.

77. Iacobellis G, F Leonetti. Epicardial adipose tissue and insulin resistance in obese subjects J

Clin Endocrinol Metab 2005; 90:6300-2.

78. Iacobellis G, MC Ribaudo, A Zappaterreno, F Leonetti Prevalence of uncomplicated obesity

in an Italian obese population: the Obesity Research 2005; 13:1116-22.

79. Iacobellis G Imaging of Visceral Adipose Tissue: An Emerging Diagnostic Tool and

Therapeutic Target Current Drug Target Cardiovascular & Haematological Disorders 2005

5;4: 345-353.

80. Iacobellis G Is obesity a risk factor for atrial fibrillation? Nature Clinical Practice

Cardiovascular Medicine 2005; 2: 134-5.


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81. Iacobellis G, D Pistilli , M Gucciardo, F Leonetti, F Miraldi, G Brancaccio , P Gallo, C di Gioia.

Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with

coronary artery disease Cytokine. 2005; 29:251-5.

82. Iacobellis G, Kemp W Cardiomyocyte apoptosis in cocaine-induced myocarditis with

involvement of bundle of His and left bundle branch International Journal of Cardiology

2005 Nov 11.

83. Iacobellis G, Cristina Ribaudo M, Zappaterreno A, Valeria Iannucci C, Leonetti F. Relationship

of thyroid function with body mass index, leptin, insulin sensitivity and adiponectin in

euthyroid obese women. Clin Endocrinol (Oxf). 2005;62: 487-91.

84. Iacobellis G, Moschetta A, MC Ribaudo, A Zappaterreno, F Leonetti Normal serum alanine

aminotransferase activity in uncomplicated obesity World Journal of Gastroenterology

2005; 11: 6018-6021.

85. C Letizia, Iacobellis G, C Caliumi, F Leonetti, D Cotesta, MC Ribaudo, M Celi, , E D’Erasmo, U

Di Mario. Plasma adrenomedullin concentrations in acute hyperinsulinemia in

uncomplicated obesity Exp Clin End& Diab 2005; 113:171-5.

86. Iacobellis G, M Curione, S Di Bona, M C Ribaudo, A Zappaterreno, E Vecci, U Di Mario F

Leoetti. No effect of acute hyperinsulinemia on QTc interval and QTc dispersion in

uncomplicated obesity. International Journal of Cardiology 2005; 99:161-3 765.

87. Silecchia S, Boru C, Pecchia A, Iacobellis G, Greco F, Rizzello M, Basso N. Prevalence of

Cancer in Italian Obese Patients Referred for Bariatric Surgery. Obesity Surgery 2005; 15:

1171-6.

88. F Leonetti, Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario. Insulin sensitivity

assessment in uncomplicated obesity: comparison of indices from fasting and oral glucose

load with euglycemic hyperinsulinemic clamp Nutrition Metabolism Cardiovascular Diseases

2004; 14:366-72.

89. Iacobellis G, R Cipriani, A Gabriele, U Di Mario, S Morano. Vascular Endothelial Growth

Factor (VEGF) is related to a better systolic function in diabetic hypertensive patients

Cytokine 2004 27; 25-30.

90. Iacobellis G , Iacobellis G A rare and asymptomatic case of mitral valve tophus associated

with severe gouty tophaceous artrhitis J Endo Investigation 2004 ;27:965-6.


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91. Iacobellis G Huge and Asymptomatic Mediastinal Goiter: Image in Thyroidology Thyroid

2004;14:635

92. F Leonetti, Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario. Acute insulin infusion

decreases plasma ghrelin levels in uncomplicated obesity. Regulatory Peptides 2004;

122:179-83.

93. Iacobellis G, Iacobellis G Combined treatment with tranexamic acid and oral contraceptive

pill causes coronary ulcerated plaque and acute myocardial infarction. Cardiovascular Drugs

and Therapy 2004: 8; 241-2. 624.

94. Iacobellis G, MC Ribaudo, A Zappaterreno, F Leonetti Adapted changes in left ventricular

structure and function in severe uncomplicated obesity. Obesity Research 2004; 12: 1616-

21.

95. Iacobellis G, MC Ribaudo, A Zappaterreno, F Leonetti. Relation between epicardial adipose

tissue and left ventricular mass American Journal of Cardiology 2004; 94:1084-7.

96. Iacobellis G True uncomplicated obesity is not related to increased left ventricular mass and

systolic dysfunction. Journal of American College of Cardiology 2004: 44:2257.

97. C Coscelli, Iacobellis G, C Calderini, R Carleo, M Gobbo, U Di Mario, F Leonetti et al.

Importance of premeal injection time in insulin therapy: Humalog MIX25 is convenient for

an improved postprandial glycemic control in type 2 diabetic patients with italian dietary

habits Acta Diabetologica 2003;40:187-92.

98. Iacobellis G, F Assael, MC Ribaudo, A Zappaterreno, U Di Mario F Leonetti

Echocardiographic epicardial adipose tissue is related to anthropometric and clinical

parameters of metabolic syndrome. A new indicator of cardiovascular risk J Clin Endocrinol

Metab 2003; 88:11.

99. Iacobellis G, F Assael, MC Ribaudo, A Zappaterreno, G Alessi, U Di Mario F Leonetti.

Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction

Obesity Research, 11; 304-310: 2003.

100. Iacobellis G, E Vecci, MC Ribaudo, A Zappaterreno, U Di Mario, F Leonetti. Relationship

of insulin sensitivity and left ventricular mass in uncomplicated obesity Obesity Research

2003 11; 518-524.

101. Iacobellis G. Uncomplicated obesity: more functional than morphological cardiac

changes Heart 7 October 2003.


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102. F Leonetti, G Silecchia, Iacobellis G, M C Ribaudo, A Zappaterreno, C Tiberti, C V

Iannucci, N Perrotta, V Bacci, MS Basso, N Basso U Di Mario Different plasma ghrelin levels

after gastric banding and gastric bypass in severe obesity J Clin Endocrinol Metab 2003 88:

4227-4231.

103. C Lepore, Iacobellis G, D Merante, G Antonucci. Inadequacy of therapeutic education: a

risk factor of hypoglycemia Diab Res Clin Pract 2003; 62/1: 61-62.

104. Iacobellis G, U Di Mario, F Leonetti. Massive epicardial adipose tissue indicating severe

visceral obesity Clin Cardiol 2003; 26:237.

105. F Leonetti, Iacobellis G, A Zappaterreno, U Di Mario. Clinical, physiopathological and

dietetic aspects of metabolic syndrome Digestive Liver Disease 2002; 34:S134-9.

106. Iacobellis G, M Puletti, A Vitarelli. Worm-shaped thrombus mimicking Chiari’s network in

a cocaine user Heart 88:4; 2002.

107. Iacobellis G. GH-producing pituitary macroadenoma, multiple epidermoid cysts and right

atrial myxoma: an unusual case of Carney Complex The Endocrinologist 2001;11: 4.

108. Iacobellis G, CRT di Gioia, G Tamburrano Asymptomatic right atrial myxoma in

acromegalic man: a case of Carney Complex. Heart; 2001; 85:86.

109. Iacobellis G, MC Ribaudo, E Vecci, G Leto, A Zappaterreno, U Di Mario, F Leonetti.

Influence of excess fat on cardiac morphology and function: study in uncomplicated obesity

Obesity Research 10; 767-773, 2002.

110. R Baldelli, E Ferretti, ML Jaffrain- Rea, Iacobellis G, G Minniti, B Caracciolo, C Moroni, R

Cassone, A Gulino, G Tamburrano. Cardiac effects of slow-release Lanreotide, a slow-release

somatostatin analog, in acromegalic patients J Clin Endocrinol Metab 1999; 84: 527-532.

111. P Gargiulo, Iacobellis G, V Vaccari, D Andreani. Diabetic cardiomyopathy:

Pathophysiological and clinical aspects Diab Nutr Metab 1998; 11: 336-346.

Books and Monographs

1. Iacobellis G. Obesity and Cardiovascular Diseases, Cardiology Oxford University Press, UK,

September 2009.

2. Iacobellis G. Drug-drug Interactions in the metabolic syndrome Nova Publishers, USA, 2006.


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Books Chapters

1. Iacobellis G. Epicardial fat thickness as a biomarker in cardiovascular disease in Biomarkers

in Disease: Methods, Discoveries and Applications. Biomarkers in Cardiovascular Disease,

edited by Victor R. Preedy and Vinood B. Patel. Springer, 2015 in press

2. Lima-Martínez M and Iacobellis G Book Title: Metabolic Syndrome: Classification, Risk

Factors and Health Impact Chapter Title: Cardiac Adiposity: Epicardial And Pericardial Fat,

Atherosclerosis, Insulin Resistance, And Other Partners In Crime Nova Science Publishers,

Inc .NY, 2012

3. Iacobellis G. Adipokines and heart damage in “Modern Insights into Disease: Adipokines”

Science Publishers USA. 2010

4. Iacobellis G and Sharma AM Obesity and Cardiovascular Diseases (chapter 12) in Obesity:

Science to Practice Wiley & Sons, 2009.

5. Iacobellis G and Sharma AM Hypertension Management in diabetic obese patient Harrison’s

Principles of Internal Medicine 2006, McGraw Hill, USA.

6. Iacobellis G and Sharma AM Treatment of obesity: a challenging task in Obesity and the

kidney, Karger Publisher, 2006; 151: 212-20.

7. Iacobellis G Cardiovascular complications related to acute and chronic cocaine abuse: from

pathogenic mechanisms to echocardiographic findings in “Cocaine Abuse: New Research”.

Nova Science Publishers, Inc.NY 2005.

8. Iacobellis G, U Di Mario. Il rischio cardiovascolare nell’obesità.IV rapporto italiano

sull’obesita’ (Istituto Auxologico Italiano) 2003 Angeli Ed.

9. Iacobellis G. Valutazioni Preliminari all’esercizio fisico.in Diabete ed esercizio: dalla teoria

alla prescrizione terapeutica ( Balducci S et al). 2003.

10. Iacobellis G. Il rischio cardiovascolare nel diabete in “Diabete ed esercizio: dalla teoria alla

prescrizione terapeutica “( Balducci S et al). 2003

11. .F Leonetti, MC Ribaudo, Iacobellis G Diabete e Chirurgia. In D Andreani, G Tamburrano

Manuale di terapia delle malattie endocrine e metaboliche. Delfino Editore 2000; 411-419.

12. M Trappolini, Iacobellis G. Classificazione delle aritmie. Cap 2 pp 9-25. In: M Trappolini, M

Comin Fibrillazione Atriale 1994 CESI editore.


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Other works, publications and abstracts

Journal Abstracts

1. Iacobellis G, Mohseni M, Bianco S. Liraglutide Causes Massive and Rapid Reduction of

Cardiac Fat Independent of Weight Loss in Type 2 Diabetes. 75th American Diabetes

Association (ADA) Scientific Sessions, 104- LB, 2015 Boston, MA

2. Poggioli R, Kim, B, Iacobellis G. Epicardial Fat Thickness Is Related To Left Ventricle

Geometry In Subjects With Coronary Artery Disease ENDO Society 94th Annual Meeting

Houston, TX, 2012

3. Iacobellis G and HC Gerstein Echocardiographic Epicardial Fat Thickness predicts the

Metabolic Syndrome Diabetes Suppl ADA San Francisco, CA, USA, 2008.

4. Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario F Leonetti Echocardiographic

epicardial adipose tissue as a new indicator of cardiovascular risk and metabolic syndrome.

Diabetes Suppl 63rd ADA 2003.

5. F Leonetti, M C Ribaudo, Iacobellis G, A Zappaterreno, C Tiberti, C V Iannucci, A Pecchia, V

Bacci, MS Basso, M Rizzello, U Di Mario. Low plasma ghrelin levels after laparoscopic gastric

banding and gastric by pass in morbid obese subjects Diabetes Suppl 63rd ADA 2003.

6. Iacobellis G, G.Silecchia, M.. Ribaudo, F Leonetti, M. S. Basso, U. Elmore, A. Pecchia, M.

Rizzello, V. Bacci, U. Di Mario. Low plasma ghrelin levels after laparoscopic gastric banding

and gastric by pass in morbid obese subjects. Obesity Surgery, 2003; 13: 487-510.

7. Iacobellis G, MC Ribaudo, F Leonetti, U Di Mario. Systolic, diastolic and related

morphological changes and not left ventricular hypertrophy in uncomplicated obesity: role

of insulin resistance. Journal of the American College of Cardiology: 39 (9) Suppl B 441B

2002.

8. Iacobellis G, D Cucinotta, A Giancaterini, S Leotta, MR Nardone, S Di Pietro. Dianeo

Project:an epidemiological study on 2674 type 2 diabetic patients at the time of diagnosis.

Diabetes 51 Suppl ,A229, 2002.

9. F Leonetti, Iacobellis G, MC Ribaudo, F Leonetti, U Di Mario. No linear correlation between

insulin sensitivity and body mass index in mild and intermediate uncomplicated obesity.

Diabetes 51 Suppl ,A604, 2002.


16

10. Iacobellis G. Movimento sistolico anteriore della corda tendinea mitralica (cSAM):curiosità

ecocardiografica o malattia della mitrale? Ital Heart J Vol 2-Suppl 6 2001.

11. Iacobellis G, MC Ribaudo, F Leonetti, U Di Mario. Energy expenditure and cardiac work. J

Endocrinol Invest 2001: Suppl n 7; P 180.

12. Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario, F Leonetti. Correlation between

insulin resistance and left ventricular mass in uncomplicated obesity. Diabetologia 2001 44:

Suppl 1:A1-A325.

13. R Cipriani, Iacobellis G, A Gabriele, C Bianchi, F Pantellini, U Di Mario, S Morano. Vascular

Endothelial Growth Factor and ventricular remodeling in patient with type 2 diabetes and

hypertension. Diabetologia 2001 44: Suppl 1:A1-A325.

14. R Cipriani, Iacobellis G, A Gabriele, A Gatti, E Mandosi, S Morano, U Di Mario. Ventricular

remodeling in patients with type 2 diabetes and hypertension: role of VEGF. J Endocrinol

Invest 2001: Suppl n 7; P 44.

15. Iacobellis G, MC Ribaudo, A Zappaterreno, F Leonetti, U Di Mario. Effects of insulin

sensitivity and not of body fat distribution on cardiac morphology and function in

uncomplicated obesity. Diabetes 50, Suppl 2. 2001.

16. F Leonetti, Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario. Insulin sensitivity index

obtained from OGTT and glucose clamp in uncomplicated obesity. Diabetes 50, Suppl 2.

2000.

17. E Ferretti, R Baldelli, ML Jaffrain-Rea, Iacobellis G, B Moneti, G Minniti, D Pietrobono, E

D’Amico, G Tamburrano. Growth hormone deficiency in adults: effects of low dose rhGH

replacement therapy on cardiac performance and cardiovascular risk. J Endocrinol Invest

1999; 22 (Suppl 4): 47.

18. P Gargiulo, Iacobellis G, V Vaccari, D Andreani. Diabetic cardiomyopathy: Pathophysiological

and clinical aspects. Diab Nutr Metab 1998; 11: 336-346.

19. Iacobellis G, R Baldelli, E Ferretti, G Minniti, ML Jaffrain-Rea, B Moneti, G Tamburrano. Role

of growth hormone in inducing myocardial hypertrophy. European Heart Journal 1998; 19:

267.

20. Iacobellis G, A De Santis. Geometria del ventricolo sinistro nell’ipertensione arteriosa in una

popolazione adulta. Cardiologia 1998; 43 (Suppl 3): 86.


17

21. R Baldelli, E Ferretti, G Minniti, Iacobellis G, A Bultrini, ML Jaffrain-Rea, G Tamburrano.

Effects of a 6 months (slow-release) Lanreotide treatment on cardiac mass in acromegaly:

correlation with changes in the GH/IGF-I axis. J Endocrinol Invest 1997; 20 ( Suppl 7).

22. Iacobellis G, G Tamburrano, G Minniti, MC Ribaudo, P Staropoli, M Puletti. Cardiomiopatia

ipertrofica ostruttiva in un giovane acromegalico: possibili fattori di crescita comuni.

Cardiologia 1997; 42 (Suppl 4): 127.

23. R Pellecchia, A De Padova, DC Zampino, R Rotunno, MC Ribaudo, R Di Placido, R Di Matteo,

N Zavatteri, A Dofcaci, K Paknejad, Iacobellis G. Telemedicina, Elettrocardiografia trans-

telefonica.Metodica in evoluzione: esperienza sul territorio. Cardiologia 1997; 42 ( Suppl 4):

120.

24. R Baldelli, E Ferretti, Iacobellis G, ML Jaffrain-Rea, G Minniti, A Bultrini, V Esposito, G

Tamburrano. Cardiological effects of a slow release lanreotide in normotensive and

hypertensive acromegalic patients. Annales d’Endocrinologie 1997; 58 ( Suppl 1):57.

25. R Baldelli, G Minniti, Iacobellis G, A Bultrini, A Paoloni, G Tamburrano. Effects of lanreotide

theraphy on echocardiographic parameters in acromegalic patients. J Endocrinol Invest

1997; 20 ( Suppl 4):56

Presentations at Meetings

Invited Presentations

26. Iacobellis G. Interplay of inflammation, immunity, and organ-specific adiposity with

cardiovascular risk. American Heart Association (AHA) Scientific Session 2015, Orlando, FL,

November 2015

27. Iacobellis G. Fat of the Heart. European Congress of Obesity (ECO 11) Istanbul 25-28 May

2011

28. Iacobellis G. Epicardial fat as new diagnostic tool and therapeutic target Italian Society of

Obesity (SIO). May 2008. Florence, Italy.

29. Iacobellis G. Morphological and functional cardiac changes in uncomplicated, metabolically

healthy obese subject. ISOH. October, 2007. International Society of Hypertension. Berlin,

Germany.


18

30. Iacobellis G. Hamilton Research in the City, New Insights from the Fatty Heart, January

2007. City of Hamilton. Hamilton, Ontario.

Oral and Poster Presentations

31. Iacobellis G, Mohseni M, Liraglutide Causes Massive and Rapid Reduction of Cardiac Fat and

Left Ventricular Mass in Type 2 Diabetes. ENDO Society Meeting OR 2016 Boston, MA

32. Iacobellis G, Mohseni M, Bianco S. Liraglutide Causes Massive and Rapid Reduction of

Cardiac Fat Independent of Weight Loss in Type 2 Diabetes. 75th American Diabetes

Association (ADA) Scientific Sessions, 104- LB, 2015 Boston, MA

33. Iacobellis G and Gerstein HC. Echocardiographic Epicardial Fat Thickness predicts the

Metabolic Syndrome. 2008. American Diabetes Association (ADA). San Francisco, California.

34. Iacobellis G and Sharma AM. Effects of Weight Loss on Epicardial Fat in Severely Obese

Subjects. 2007. North American Association for Obesity (NAASO). New Orleans.

35. Iacobellis G et al. Echocardiographic Epicardial Fat Thickness and Metabolic Syndrome SIC.

2007. Italian Society of Cardiology. Rome, Italy.

36. Iacobellis G, Willens H et al. Ethnic Differences in Echocardiographic Epicardial Fat

Thickness. 2007. American College of Cardiology (ACC). New Orleans.

37. Iacobellis G and Sharma AM. Epicardial Adipose Tissue; Anatomy and Clinical Role. 2006.

North American Association for Obesity (NAASO). Boston, Massachusetts.

38. Iacobellis G. Uncommon low metabolic and cardiovascular risk profile in Italian obese

population: The prevalence of uncomplicated obesity. 2004. North American Association for

Obesity (NAASO). Las Vegas, Nevada.

39. Iacobellis G , F Leonetti, F Miraldi, C di Gioia. ADA Annual Meeting. Adiponectin expression

in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease.

2004. American Diabetes Association (ADA). Orlando, Florida.

40. Iacobellis G , F Leonetti, F Miraldi, C di Gioia. Adiponectin expression in human epicardial

adipose tissue in vivo is lower in patients with coronary artery disease. SID Meeting. May,

2004. Italian Society of Diabetes. Rome, Italy.


19

41. Iacobellis G, MC Ribaudo, A Zappaterreno, C V Iannucci , F Leonetti, U Di Mario. Plasma

adiponectin is related to epicardial adipose tissue in uncomplicated obesity.18th

International Diabetes Annual Meeting, August, 2003. International Diabetes (IDF). Paris,

France.

42. 6Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario F Leonetti Echocardiographic

epicardial adipose tissue as a new indicator of cardiovascular risk and metabolic syndrome.

63rd American Diabetes Association Annual Meeting, 2003. American Diabetes Association.

United States.

43. F Leonetti, M C Ribaudo, Iacobellis G, A Zappaterreno, C Tiberti, C V Iannucci, A Pecchia, V

Bacci, MS Basso, M Rizzello, U Di Mario. Low plasma ghrelin levels after laparoscopic gastric

banding and gastric by-pass in morbid obese subjects 63rd ADA 2003. American Diabetes

Association (ADA). United States.

44. Iacobellis G, MC Ribaudo, A Zappaterreno, CV Iannucci , F Leonetti, U Di Mario.

Echocardiographic epicardial adipose tissue as a new indicator of cardiovascular risk and

metabolic syndrome XXX SIE. September 2003 Milan,. Italian Society of Endocrinology. Italy.

45. Iacobellis G, MR Nardone, S Di Pietro. Gestione informatizzata dell’assistenza alle

complicanze invalidanti della malattia diabetica XIII Congresso Nazionale AMD Torino 9-12

Maggio 20. Italian Society of Diabetes. Italy. 2003.

46. MR Nardone, Iacobellis G, P Borboni, S De cosmo, G De Mattia, N Dozio, G Ghirlanda, G

Pugliese, F Purrello, S Dipietro. Progetto EDI: epidemiologia diabete informatica XIII

Congresso Nazionale AMD Torino 9-12 Maggio 20. Italian Society of Diabetes. Italy. 2003.

47. C Coscelli, D Cucinotta, S Di pietro, C Giorda, Iacobellis G, MR Nardone. Progetto Dianeo:

dati preliminari su 635 diabetici tipo 2 neodiagnosticati XIII Congresso Nazionale AMD

Torino 9-12 Maggio 20. Italian Society of Diabetes. Italy. 2003.

48. Iacobellis G, M. Curione, MC. Ribaudo, P. Francia, S. Di Bona, S. Missori, A. Zappaterreno, U.

Di Mario, F. Leonetti. Acute hyperinsulinemia induces sympathetic shift of autonomic

balanceand not QT interval prolongation in uncomplicated obesity. May, 2002. European

Group Insulin Resistance (EGIR). Greece.

49. Iacobellis G, MC Ribaudo, F Leonetti, U Di Mario. Systolic, diastolic and related

morphological changes and not left ventricular hypertrophy in uncomplicated obesity: role

of insulin resistance 2002 World Congress of Cardiology, Sidney Australia. Sidney, Australia.


20

50. Iacobellis G, MC Ribaudo, A Zappaterreno, F Assael, F Leonetti, U Di Mario. Epicardial fat

detection by echocardiography: a new reliable imaging method for the assessment of

visceral adipose tissue 2002 62nd ADA, USA. American DIabetes Association (ADA). United

States.

51. Iacobellis G, D Cucinotta, A Giancaterini, S Leotta, MR Nardone, S Di Pietro. Dianeo Project:

an epidemiological study on 2674 type 2 diabetic patients at the time of diagnosis. Italian

Society of Diabetes. Italy. 2002.

52. F Leonetti, Iacobellis G, MC Ribaudo, F Leonetti, U Di Mario. No linear correlation between

insulin sensitività and body mass index in mild and intermediate uncomplicated obesity

2002 62nd ADA, USA. American Diabetes Association (ADA). United States.

53. Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario, F Leonetti. L’ecocardiografia come

facile e riproducibile metodica per l’individuazione del tessuto adiposo viscerale:studio del

grasso epicardio. SIC. Rome, Italy. 2002. Italian Society of Cardiology.

54. Iacobellis G, M Curione, MC Ribaudo, S Di Bona, A Zappaterreno, U Di Mario, F Leonetti.

Effetti dell’insulinizzazione acuta sull’equilibrio simpato-vagale e non sull’intervallo QT

nell’obesità non complicata SIC. 2002, Rome, Italy.

55. Iacobellis G, Cipriani R, Mandosi E, Pantellini F, Sensi M, Di Mario U, Morano S. IlVEGF è

correlato al rimodellamento ventricolare sinistro, ma non alla funzione renale in pazienti

con diabete di tipo 2 ed ipertensione arteriosa. 19° Congresso SID, Verona 22-25 Maggio

2002. Italian Society of Diabetes. Italy.

56. Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario, F Leonetti. Studio del grasso

epicardio con l’ecocardiografia: una nuova e riproducibile metodica per la valutazione del

tessuto adiposo viscerale. 19° Congresso SID, Verona 22-25 Maggio 2002. Italy.

57. Iacobellis G, A Giancaterini, MR Nardone, S Di Pietro. Come si curano e cosa si aspettano e

temono del futuro i pazienti diabetici in Italia: risultati di unb questionario multicentrico 19°

Congresso SID, Verona 22-25 Maggio 2002. Italian Society of Diabetes (SID). Italy.

58. F Leonetti, Iacobellis G, MC Ribaudo, F Leonetti, U Di Mario. Il BMI costituisce un parametro

predittivo dell’insulinoresistenza solo nell’obesità di grado severo 19° Congresso SID,

Verona 22-25 Maggio 2002. Italy.

59. Iacobellis, MC. Ribaudo, A. Zappaterreno, S. Missori, U. Di Mario. Correlation between

insulin sensitivity and leptin in uncomplicated obesity: role of body mass index EGIR Annual

Meeting 10-12 May Santorini (Greece) 2002.


21

60. F Leonetti, Iacobellis G, MC Ribaudo, F Leonetti, U Di Mario. Variabilità della sensibilità

insulinica nell’obesità non complicata. I° Congresso SIO , Verona 17-20 Aprile 2002. Italian

Society of Obesity (SIO). Italy.

61. Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario, F Leonetti. Studio del grasso

epicardio con l’ecocardiografia: una nuova e riproducibile metodica per la valutazione del

tessuto adiposo viscerale. I° Congresso SIO , Verona 17-20 Aprile 2002. Italy.

62. Iacobellis G Movimento sistolico anteriore della corda tendinea mitralica (cSAM):curiosità

ecocardiografica o malattia della mitrale? SIC 2001

63. Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario, F Leonetti. Correlation between

insulin resistance and left ventricular mass in uncomplicated obesity EDS 2001. European

Society of Diabetes. Italy.

64. R Cipriani, Iacobellis G, A Gabriele, C Bianchi, F Pantellini, U Di Mario, S Morano. Vascular

Endothelial Growth Factor and ventricular remodeling in patient with type 2 diabetes and

hypertension. EDS 2001. Italy.

65. F Leonetti ,Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario Insulin resistance and left

ventricular morphology in uncomplicated obesity EGIR Goteborg, Svezia 18-19 Maggio

2001. Sweden.

66. R Cipriani, Iacobellis G, A Gabriele, A Gatti, E Mandosi, S Morano, U Di Mario. Ventricular

remodeling in patients with type 2 diabetes and hypertension: role of VEGF SIE 2001. Italian

Society of Endocrinology (SIE). Italy.

67. Iacobellis G, MC Ribaudo, A Zappaterreno, F Leonetti, U Di Mario. Effects of insulin

sensitivity and not of body fat distribution on cardiac morphology and function in

uncomplicated obesity. ADA 2001. Pennsylvania, United States.

68. F Leonetti, Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario. Insulin sensitivity index

obtained from OGTT and glucose clamp in uncomplicated obesity. American Diabetes

Association, 2001. ADA. United States.

69. Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario, F Leonetti. Energy expenditure is not

related to cardiac performance in uncomplicated obesity 5th European Congress of

Endocrinology. Torino 9-13 Giugno 2001. European Congress of Endocrinology. Italy.


22

70. Iacobellis G, MC Ribaudo, A Zappaterreno, U Di Mario, F Leonetti. Severe uncomplicated

obesity does not worsen left ventricular mass and function. Torino 9-13 Giugno 2001. 5th

European Congress of Endocrinology.

71. F Leonetti, A Zappaterreno, MC Ribaudo, Iacobellis G, U Di Mario. Indice di sensibilità

insulinica ottenuto con l’OGTT comparato con il glucose clamp nel soggetto obeso. XIII

Congresso Nazionale AMD Torino 9-12 Maggio 2001. Italian Diabetes Association (AMD).

Italy.

72. Iacobellis G, R Cipriani, A Gabriele, C Bianchi, F Pantellini, U Di Mario, S Morano . VEGF e

rimodellamento ventricolare sinistro nel diabete senza ipertensione XIII Congresso

Nazionale AMD Torino 9-12 Maggio 2001. Italy.

73. Iacobellis G. Correlazioni tra la massa ventricolare sinistra e la massa magra nell’obesità

semplice X Congresso Nazionale della Società Italiana di Ecocardiografia Milano 20-23

Giugno 2001. Italian Society of Echocardiography. Italy.

74. Iacobellis, MC. Ribaudo, A. Romiti, A. Zappaterreno, F. Leonetti, U. Di Mario. Morfologia e

funzione cardiaca nell’obesita’ severa non complicata da ipertensione arteriosa. SIC 2001.

Italy.

75. R Baldelli, A Colao, E Ferretti, P Marzullo, D Ferone, Iacobellis G, G Tamburrano, G Lombardi.

Role of GH/IGF-I excess, systemic hypertension and abnormalities of glucose tolerance on

acromegalic cardiomyopathy: an echocardiographic study on 105 patients , . June 12-15,

1999 San Diego, California. ENDO ’99, the Endocrine society’s 81st annual meeting.

California, United States.

76. E Ferretti, R Baldelli, ML Jaffrain-Rea, Iacobellis G, B Moneti, G Minniti, D Pietrobono, E

D’Amico, G Tamburrano. Growth hormone deficiency in adults: effects of low dose rhGH

replacement therapy on cardiac performance and cardiovascular risk. SIE 1999. Italian

Society of Endocrinology (SIE). Italy.

77. MC Ribaudo, M Merli, O Riggio, V Valeriano, M D’adamo, Iacobellis G, A Zappaterreno, F

Leonetti. Valutazione della leptina plasmatica nel paziente cirrotico. Atti del 100° Congresso

Nazionale della Societa’ Italiana di Medicina Interna 18 –22 Ottobre 1999, Roma. Italian

Society of Internal Medicine (SIMI). Italy.

78. Iacobellis G, A Vitarelli, M Puletti. Trombo serpiginoso simulante la rete di Chiari in un

giovane cocainomane. Atti del IX Congresso Nazionale della Societa’ Italiana di

Ecocardiografia Cardiovascolare 20-23 Aprile 1999, Milano. Italian Society of

Echocardiography. Italy.


23

79. Iacobellis G, L Cipollone, A Camagna. Insolita localizzazione di linfoma non-Hodgkin. Atti del

IX Congresso Nazionale della Societa’ Italiana di Ecocardiografia Cardiovascolare 20-23

Aprile 1999, Milano. Italian Society of Echocardiography. Italy.

80. Iacobellis G, S Morano, G Tamburrano. Diagnosi ecocardiografica di aortite luetica. Atti del

VIII Congresso Nazionale della Societa’ Italiana di Ecocardiografia Cardiovascolare 21-24

Aprile 1999, Milano. Italian Society of Echocardiography. Italy.

81. Iacobellis G , E Ferretti, R Baldelli, G Minniti, ML Jaffrain-Rea, A Bultrini, G Tamburrano.

Valutazione ecocardiografica dell’efficacia di un farmaco long-acting, Lanreotide, nella

cardiopatia acromegalica. Atti del VIII Congresso Nazionale della Societa’ Italiana di

Ecocardiografia Cardiovascolare 21-24 Aprile 1999, Milano. Italian Society of

Echocardiography. Italy.

82. Iacobellis G, R Baldelli, E Ferretti, G Minniti, ML Jaffrain-Rea, B Moneti, G Tamburrano. Role

of growth hormone in inducing myocardial hypertrophy ESC 1998; Wien, Austria. European

Society of Cardiology (ESC).

83. Iacobellis G, A De Santis. Geometria del ventricolo sinistro nell’ipertensione arteriosa in una

popolazione adulta SIC 1998, Rome, Italy.

84. Iacobellis G, R Baldelli, E Ferretti, G Minniti, ML Jaffrain-Rea, B Caracciolo, A Bultrini, G

Tamburrano. L’ecocardiografia nello studio della cardiomiopatia acromegalica. II° Workshop

neuroendocrinologica multidisciplinare 17-18 Aprile 1998, Padova. Italy.

85. G Tamburrano, Iacobellis G, R Baldelli, E Ferretti, G Minniti, ML Jaffrain-Rea, B Caracciolo, A

Bultrini. Eziopatogenesi della cardiomiopatia acromegalica. II° Workshop

neuroendocrinologica multidisciplinare 17-18 Aprile 1998, Padova.

86. Iacobellis G, M Mellozzi, A Balduzzi, R Baldelli, G Tamburrano. Possibile azione Ca-

antagonista di un analogo della somatostatina: lanreotide. Atti del 99° Congresso nazionale

della Societa’ Italiana di Medicina Interna 10-14 Novembre 1998, Bari. SIMI. Italy.

87. Iacobellis G, G Tamburrano, R Baldelli, E Ferretti, M Puletti. Movimento sistolico anteriore

(SAM) della mitrale in un giovane acromegalico: una causa in più di SAM . Atti del 99°

Congresso nazionale della Societa’ Italiana di Medicina Interna 10-14 Novembre 1998, Bari.

SIMI. Italy.


24

88. R Baldelli, Iacobellis G, E Ferretti, ML Jaffrain-Rea, P Sbraccia, G Tamburrano. Short- term

effects of Lanreotide injection on echocardiographic parameters in acromegaly. ENDO ’97,

79th Annual Meeting, June 11-14 , 1997 Minneapolis, Minnesota. ENDO ’97, the Endocrine

Society 79th Annual Meeting. United States.

89. R Baldelli, E Ferretti, G Minniti, Iacobellis G, A Bultrini, ML Jaffrain-Rea, G Tamburrano.

Effects of a 6 months (slow-release) Lanreotide treatment on cardiac mass in acromegaly:

correlation with changes in the GH/IGF-I axis SIE 1997. Italy.

90. Iacobellis G, G Tamburrano, G Minniti, MC Ribaudo, P Staropoli, M Puletti. Cardiomiopatia

ipertrofica ostruttiva in un giovane acromegalico: possibili fattori di crescita comuni. SIC

1997, Rome, Italy.

91. R Pellecchia, A De Padova, DC Zampino, R Rotunno, MC Ribaudo, R Di Placido, R Di Matteo,

N Zavatteri, A Dofcaci, K Paknejad, Iacobellis G. Telemedicina, Elettrocardiografia trans-

telefonica. Metodica in evoluzione: esperienza sul territorio SIC 1997, Rome, Italy.

92. R Baldelli, E Ferretti, Iacobellis G, ML Jaffrain-Rea, G Minniti, A Bultrini, V Esposito, G

Tamburrano. Cardiological effects of a slow release lanreotide in normotensive and

hypertensive acromegalic patients , Paris 1997. European Society of Endocrinology. France.

93. R Baldelli, G Minniti, Iacobellis G, A Bultrini, A Paoloni, G Tamburrano. Effects of lanreotide

theraphy on echocardiographic parameters in acromegalic patients SIE 1997. Italy.

94. Iacobellis G, R Baldelli, E Ferretti, G Minniti, A Bultrini, ML Jaffrain Rea, G Tamburrano.

Effetti del trattamento con SR-Lanreotide sulla massa ventricolare sinistra nell’acromegalia:

correlazioni tra ipertrofia miocardica e fattori di crescita . Atti del 98° Congresso nazionale

della Societa’ Italiana di Medicina Interna 27-31 Ottobre 1997, Roma. SIMI. Italy.

95. A Napoli, A Sabbatini, E Borrello, N Di Biase, RM Marceca, Iacobellis G, F Fallucca .

Ambulatory blood pressure monitoring in diabetic pregnancy Joint International Meeting on

Diabetes and Pregnancy in the mediterranean areas 24-26 June 1996, Roma. Italy.

96. Iacobellis G, F Medici, A Gabriele, R Cipriani, L Guidobaldi, S Morano. Alterazioni

ecocardiografiche in corso di diabete mellito tipo 2: influenza della durata di malattia e del

controllo metabolico. Il Diabete 1996; 8 (Suppl 1 ): 106. SID. Italy.

97. A Sabbatini, E Borrello, MG Russo, Iacobellis G, A Napoli, A Maldonato, F Fallucca.

Valutazione critica di differenti schemi di terapia insulinica nel diabete IDDM-tipo 1 seguiti

presso il Servizio di Diabetologia del Policlinico Umberto I dell’ Universita’ “ La Sapienza “ di

Roma . Il Diabete 1996; 8 (Suppl 1 ): 217. SID. Italy.


25

Grand Round Presentations

98. Iacobellis G. Cardiology Grand Rounds: Epicardial fat: the cardiology and endocrinology

connnection University of Miami. April 2016. Miami, Florida

99. Iacobellis G. Medical Grand Rounds: Uncontrolled type 2 diabetes: would you primarily

target the glucose or the fat? University of Miami. February 2016. Miami, Florida

100. Iacobellis G. Medical Grand Rounds: Epicardial fat: clinical and research implications.

University of Miami. November 2010. Miami, Florida

101. Iacobellis G. Grand Rounds: New insights in Obesity and Cardiometabolic Risk.

University of Miami. February 2009. Miami, Florida.

102. Iacobellis G. Epicardial Fat in Cardio-Metabolic Research and Clinical Practice. Institute

Clinical Research Montreal (IRCM). Montreal, Quebec. Oct 2009.

103. Iacobellis G. New Insights in Obesity and Cardiometabolic Risk University of Miami.

Miami, Florida. Feb 2009.

104. Iacobellis G. Epicardial Fat and Cardiovascular Disease. The Ottawa Heart Institute,

Ottawa, Ontario. Sep 2008.

105. Iacobellis G. Endocrine Rounds: Epicardial Fat. McMaster University. Hamilton, Ontario.

May 2008.

106. Iacobellis G. Endocrine Grand Rounds: Epicardial Fat. University of Miami. March 2007.

University of Miami. MIami, Florida.

107. Iacobellis G. Endocrine Rounds: Role of Epicardial Fat in Cardiometabolic Disease.

University of Miami. Miami, Florida. Mar 2007.

108. Iacobellis G. Obesity and Cardiovascular Diseases. McMaster Regional and

Research Rounds. 2005. McMaster University. Hamilton, Ontario.


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� GRANTS

Funded Research Performed

Grants Peer Reviewed

2016-present R24 Grant

Novel substrate stabilization therapy for atrial fibrillation

Role: co-PI

Status: under review

Sponsor: NIH-NHLBI

Funding: $695,000

2015-present Initiated Investigator Study (IIS)

Clinical Trial: NCT01919489

Liraglutide Discharge Trial

Role: Principal Investigator

Status: funded

Sponsor: Novo Nordisk

Funding: $136,500


Clinical Trial: NCT 02235298

Effects of Dapglifozin On Epicardial Fat In subjects with Type 2

Diabetes


Status: funded, enrolling

Sponsor: Astra Zeneca

Funding: $ 235,000


Clinical Trial: NCT 2014740

Effects of Liraglutide On Epicardial Fat In Type 2 Diabetic Subjects


Status: enrolling


Funded: $ 285,000


27

2013-present University of Miami, Pilot Study

Epicardial Fat as Brown Fat in Coronary Artery Disease


Status: completed

Funded: This study was funded with support from the National

Institute of Diabetes and Digestive and Kidney Diseases

2011-present NIH funded study PI Dr Carrasquillo

Miami Healthy Heart Initiative (MHHI)

Role: co-investigator

Status: enrolling

Funds: hospital (UMH/JMH) collaborative study

2010-2013 University of Miami, Clinical Trial #20090234

“High HDL in type 1 diabetes”

Dr Goldberg PI, Role: Iacobellis G co-Investigator

Status: completed

2008 -2010 St. Joseph’s Healthcare, McMaster University, Clinical Trial, Anti-

depressants and regional fat distribution,

Dr Taylor PI, Role: Iacobellis G Co-Investigator

Status: completed

Funded: $9,000.00

2008 - 2013 Novo-Nordisk Global, Collab/Partnerships Research -

Effect of Insulin Detemir on Epicardial Adipose Tissue Thickness in

type 2 diabetic subjects” Investigator initiated trial (ITT)


Status: completed


Funded: $35,000

2007 - 2010 Clinical Trial

Clinical Trial: NCT00428571,

Laparoscopic Bariatric Surgery to Treat Type 2 Diabetes in Obese

Patients,

Dr Anvari, PI; Role: Iacobellis G, co-investigator

Status: completed

Funded: $30,000


28

2007 Educational Grant of for Excellence in Clinical and Educational

Service in Obesity and Diabetes, Abbott Canada, Education

Research,


Status: completed

funded: $45,000.00

2006 - 2007 Cardiovascular Obesity Research Management, Clinical Trial

Grant,

Effect of weight loss on epicardial fat thickness in severely obese

subjects,


Status: completed

funded: $30,000.00

2000 - 2002 Controlled Randomized Clinical Trial, Humalog MIX in diabetic

obese subjects, All Categories, Eli Lilly, Collab/Partnerships

Research - Collaborative - General,

Role:, co-Investigator

Status: completed

Sponsor: Eli Lilly

Funded: $10,000.00

Editorial responsibilities

Executive Positions

2008 - present Editor-in-Chief “Journal of EndoCardiology

2016-present Associate Editor “CardioRenal Medicine”

Editorial Boards

2015-present American Diabetes Association (ADA) Referee

2014-present Endocrine, Springer

2013-present International Journal Endocrinology

2009 - present Journal of Obesity

2007 - 2010 Current Pharmaceutical Design

2006 - 2010 Recent Patents on Endocrine, Metabolic & Immune Drugs


29

Journal Referee

Journal of Clinical Endocrinology & Metabolism

International Journal of Obesity

Journal American Society of Echocardiography

Clinical Endocrinology

Hormones and Metabolic Research

Circulation

Nutrition Metabolic and Cardiovascular Disease

Journal of American College of Cardiology

International Journal of Cardiology

American Journal of Cardiology

Obesity

Endocrinology

Annals of Nutrition

Endocrine

Journal of Endocrinology Investigation

Cancer Prevention Research

Pediatric Endocrinology

Diabetes Obesity and Metabolism

Honors and Awards

2006 - 2009 Internal Career Award, McMaster University, $90,000

2008 Abbott Pharmaceuticals, Educational Grant for Excellence in Clinical and

Educational Service in Obesity and Diabetes, $45,000

2008 Italian Ministry of University Research (MIUR), Rientro dei Cervelli (Brain

Gain)

2002 Pfizer Competitive Awards Program for Cardiovascular Proposals

Professional and Honorary Organizations

2012-present American Society of Echocardiography (ASE), invited member

2005 - present Canadian Obesity Network (CON), member

2000 - present Italian Society of Endocrinology (SIE), member


30

2000 - present Italian Society of Diabetology (SID), member

2000 - present Italian Society of Cardiology (SIC), member

2000 - present European Group for the study of Insulin Resistance (EGIR), member

Advisory Boards

2016 Reviewer for the American Diabetes Association (ADA)'s 75th Scientific Sessions

2015 Advisory Board Jansen-Jansen

2015 Reviewer for the American Diabetes Association (ADA)'s 75th Scientific Sessions

2007 Scientific Advisory Board International Academy of Cardiology

2007 - 2009 Advisory Board Member Abbott Canada

2008 Levemir, Advisory Board Member Novo-Nordisk Global

2008 Diabetes in Obesity Advisory Board Member Novo-Nordisk Global

2008 Liraglutide Advisory Board Member Novo-Nordisk Global


31

� TEACHING

Postgraduate Teaching

2015 Mentor of University of Miami Endocrine Fellow, Dr Mahshid

Mohseni MD, who published 1 ADA abstract under my guidance

2014 Mentor of University of Miami Endocrine Fellow, Dr Elizabeth

McAninch MD, who achieved career advancement (appointed

assistant professor at Rush University) and published 1 peer-

reviewed publication under my guidance.

2014 Mentor of University of Miami Endocrine Fellow, Dr Chengy Xu

MD who published 2 peer-reviewed publications under my

guidance

2012 Mentor of University of Miami Endocrine Fellow, Dr Raffaella

Poggioli MD , who published 1 peer-reviewed publication under

my guidance

2011-present Research supervisor 2nd year Endocrine Fellow , Endocrinology

fellowship program, University of Miami

2010- present Supervisor of Endocrine Fellows at ACC Diabetes Clinic JMH,

University of Miami

2010-present Core Lectures Series, Endocrine Fellows at ACC Diabetes Clinic

JMH, University of Miami

2009-2010 Mentor of McMaster University Fellow, Dr Navneet Singh , who

published 3 peer-reviewed publications under my guidance

2009l - 2010 Advisor, Research, Endocrinology McMaster University

2009 - 2010 Presenter, Academic Half-Day “Clinical Management of Obese

Patients” McMaster University

2009 - 2010 Presenter, Clinical Teaching Unit “Discussion of Clinical Cases on

Obesity” McMaster University


32

2009 - 2010 Clinical Supervisor, Endocrinology Outpatient Clinics McMaster

University

2006 - 2009 Supervisor, Clinical, Elective Block, McMaster University

2006 - 2007 Supervisor, Clinical Rotation, McMaster University

2006 - 2010 Research Supervisor, McMaster University

Undergraduate Medical

2011-present Tutor, 2nd year Medical School Students Small-group in

Endocrinology, University of Miami, Miller School of Medicine

2011-present Supervisor Visiting Students Endocrine Service Rotation University

of Miami, Miller School of Medicine

2009 Jul - 2010 Jun Tutor, MF2 McMaster University Medical Foundations

“Endocrinology, Gastroenterology, Nutrition”

2004 - 2005 Biochemistry Laboratory Practicum, University of Texas

Southwestern Medical Centre, TX, USA

2000 - 2003 Endocrinology and Metabolism, University of Rome, La Sapienza,

Italy


33

Speaker at Continuing Medical Education (CME)

November 2012 Speaker: CME Division of the Miller School of Medicine and the

Division of Endocrinology, Diabetes and Metabolism Treatment

April 2012 Speaker: CME symposium Primary Care Update.

“Obesity: Achieving Lean Body Mass in Diabetes”

February, 2012 Speaker: Current Clinical Issues in Primary Care, Ask the Expert

Harvard University/ University of Miami, Pri-MED south

May, 11, 2011 Speaker: Medical Grand Rounds “Epicardial fat: research and

Clinical applications” University of Miami

2007 Jul - 2008 Jun Speaker - “New Insights in Diabetes Treatment” (Canadian

Endocrine Update);

2006 Jul - 2007 Jun Speaker - “Fatty Hearts: What are the Consequences of Obesity”

(Health Research in the City); “Canadian Endocrine Update”

(University of London)

Other

Silver and Bronze Medalist at the Italian Swimming Juvenile championships in 1984 and 1985

Married with Matilde PhD Biologist in Aquaculture; two daughters, Lavinia & Lucrezia

Documents

Gianluca Iacobellis MD PhD - Physicians Database Loginphydatabase.med.miami.edu/documents/cv/Iacobellis.Gianluca_95878...Dr Iacobellis CV December 2016 1 Curriculum Vitae Gianluca