Genetics of Schizophrenia Presenter : Dr Pavan Kumar Chairperson
: Dr Abhijeet
The risk of a disease in a type of relative compared to that in
the general population is often called . The relative risk to
siblings resulting from having a proband with the illness is called
s. Common disorders have a smaller s than rare disorders, even with
similar overall genetic effects.the s for major adult psychiatric
disorders of the adult typically are under 10 (s is ~10 for
schizophrenia).The risk for schizophrenia to a relative of an
affected proband decays much more rapidly than the proportion of
genes shared between them, which is also inconsistent with a simple
Mendelian model
