Genetics GameAutosomal Recessive Inheritance

Autosomal Dominant Inheritance

Sex-Linked Inheritance

1)Which choice(s) are examples of homozygous recessive genotypes?

1. TT 6. XY

2. Tall 7. gg

3. Hh 8. Dwarf

4. pp 9. yY

5. Wrinkled 10. hh

2) Name 3 out of 7 traits of pea plants Gregor Mendel studied?

3) What is the genotype of the child, assuming autosomal recessiveness?

4) What do you call a gene that is hidden?

5) Using below Punnett Square results, what is the chance a child would be born healthy (autosomal dominant disorder)?

H h

H

h

HH Hh

Hh hh

6) What are chromosomes 1-22 referred as?

7) Two part question:

a)Are men or women more likely to inherit sex-linked disorders

b)who do they usually inherit the disorder from?

8) Steve is a normal pigmented man with no history of albinism in his family, and he marries Anne, an albino woman. Albinism is an autosomal recessive disorder. Steve and Anne have a child. What is the probability that child will be an albino?

(Hint: Draw a Punnett Square if it would help.)

9) Three part question:

a)What does a shape with a dot in the middle signify?

b)What is the genotype of this person assuming autosomal recessive inheritance?

c)What is the genotype of this person assuming sex-linked inheritance?

10) Harry is color blind, which is a sex-linked disorder. He married Ginny who is not color blind but whose father was color blind. What is the probability their first born son will be color blind?

(Hint: Use a Punnett Square or pedigree to help figure out.)

11) Alternative versions of genes are called?

12) If you flip a coin:

a. What is the probability of getting heads?

b. What is the probability of getting HEADS four times in a row?

13) Aicardi Syndrome is a dominant disorder found on the X chromosome of males and females. Michelle is heterozygous for Aicardi syndrome, but her husband Jerry is completely healthy. List the genotypes in the F1 generation. (Use a Punnett Square.)

14) Selena is a carrier of PKU. Her parents were also both carriers of this recessive disorder. She marries Justin, who is heterozgyous for PKU. They have three kids, two boys and a girl. Their daughter has been showing signs of PKU. Draw a pedigree of their family, including genotypes.

2 Unknowns

15) Fill in the missing genotype and explain how you know.

16) Write out the two types of genotypes a male can have when referring to sex-linked disorders. (Use the letter H.)

17) What is the genotype of the child, assuming sex-linked inheritance?

18) Where was Gregor Mendel from and what was his profession?

19) Huntington’s Disease is an autosomal dominant disorder. Kelly had Huntington’s disease and before she died at the age of 38, she married and had 2 kids. Her husband, Fred, was completely healthy. What are the chances that both her children will be born with Huntington’s disease?

(Hint: Use a Punnett Square if needed to solve.)

20) Grab-Bag: Name 5 songs of Michael Jackson.

Exchange answers and correct.

1)Which choice(s) are examples of homozygous recessive genotypes?

1. TT 6. XY

2. Tall 7. gg

3. Hh 8. Dwarf

4. pp 9. yY

5. Wrinkled 10. hh

4, 7, 10

2) Name 3 out of 7 traits of pea plants Gregor Mendel studied?

Seed TextureSeed ColorPod ShapeFlowerPositionStem HeightPod ColorFlower Color

3) What is the genotype of the child?

hh

4) What do you call a gene that is hidden? RECESSIVE

5) Using below Punnett Square results, what is the chance a child would be born healthy (autosomal dominant disorder)?

H h

H

h

HH Hh

Hh hh

¼ or 25%

6) What are chromosomes 1-22 referred as? AUTOSOMES

7) Two part question:

a)Are men or women more likely to inherit sex-linked disorders

b)who do they usually inherit the disorder from?Men

Mother

8) Steve is a normal pigmented man with no history of albinism in his family, and he marries Anne, an albino woman. Albinism is an autosomal recessive disorder. Steve and Anne have a child. What is the probability that child will be an albino?

(Hint: Draw a Punnett Square if it would help.)

0%

9) Three part question:

a)What does a shape with a dot in the middle signify?

b)What is the genotype of this person assuming autosomal recessive inheritance?

c)What is the genotype of this person assuming sex-linked inheritance?

Person is a carrier.

Hh

XH Xh

10) Harry is color blind, which is a sex-linked disorder. He married Ginny who is not color blind but whose father was color blind. What is the probability their first born son will be color blind?

(Hint: Use a Punnett Square or pedigree to help figure out.)

½ or 50%

11) Alternative versions of genes are called? ALLELES

12) If you flip a coin:

a. What is the probability of getting heads?

b. What is the probability of getting HEADS four times in a row?

50% or ½

1/16

13) Aicardi Syndrome is a dominant disorder found on the X chromosome of males and females. Michelle is heterozygous for Aicardi syndrome, but her husband Jerry is completely healthy. List the genotypes in the F1 generation. (Use a Punnett Square.)

XHXh XhXh

XHY XhY

14) Selena is a carrier of PKU. Her parents were also both carriers of this recessive disorder. She marries Justin, who is heterozgyous for PKU. They have three kids, two boys and a girl. Their daughter has been showing signs of PKU. Draw a pedigree of their family, including genotypes.2 Unknowns

15) Fill in the missing genotype and explain how you know.

Hh, because in order for parents to have kid with disease, both must have a little h, and mom must also have big H since she is healthy.

16) Write out the two types of genotypes a male can have when referring to sex-linked disorders. (Use the letter H.)

XHYXhY

17) What is the genotype of the child, assuming sex-linked inheritance?

Xh Y

18) Where was Gregor Mendel from and what was his profession?

AUSTRIA MONK

19) Huntington’s Disease is an autosomal dominant disorder. Kelly had Huntington’s disease and before she died at the age of 38, she married and had 2 kids. Her husband, Fred, was completely healthy. What are the chances that both her children will be born with Huntington’s disease? (Hint: Use a Punnett Square if needed to solve.)

¼ or 25%

20) Grab-Bag: Name 5 songs of Michael Jackson. Thriller

BadBeat ItBillie JeanBlack and WhiteDirty DianaPYTRemember the TimeRock With YouMan in the MirrorSmooth CriminalJamScreamWanna Be Startin’ SomethingHuman NatureWorking Day & Night