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GDME0156MAR / Published APR 2012 Page 1 Mobile Health Devices and Applications - Global Market Briefing to 2018 © GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form Mobile Health Devices and Applications - Global Market Briefing to 2018 Reference Code: GDME0156MAR Publication Date: April 2012 The Global Market for Mobile Health (mHealth) is Forecast to Grow at a Compound Annual Growth Rate (CAGR) of XX% from 2010-2018 mHealth Market, Global, Revenue ($bn), 2010-2018 2010 2018 Revenue ($bn) CAGR(2010-2018): XX% Source: GlobalData, Annual Reports, SEC Filings, Investor Presentations, Earning Call Transcripts, News and Press Releases, Scientific Journals, Trade Associations, Interviews with Industry Experts and Key Opinion Leaders (KOLs) The global market for Mobile Health (mHealth) technology, estimated to be valued at about $XX billion in 2010, is forecast to grow at a Compound Annual Growth Rate (CAGR) of XX% to exceed $XX billion by 2018. This market includes mHealth devices and peripherals and mHealth applications and services. The exponential growth of this market can be attributed to the significant impetus provided by stakeholders across the healthcare spectrum. Mobile technologies have shown in recent years to be capable of enhancing healthcare delivery and management while limiting the burden they impose on the economy. They have been proven to improve patient and physician convenience, enable remote monitoring and improvise care-coordination among providers, patients, public health systems and payors. The Rapid Emergence of Mobile Health (mHealth) Technology is Expected to Revolutionize Health Delivery and Management in the Future The use of mobile technology to enhance healthcare delivery and management has evolved significantly in the past five to seven years. During this period, the adoption of mobile technology in all facets of day-to-day life as well as business activities has emerged rapidly. On the other hand, the same period saw the global healthcare industry address concerns related to cost efficiency, improvement in clinical outcomes and expansion of access to care through the adoption of advanced technologies. The digitalization of medical information and exchange of this information through a connected healthcare infrastructure are key changes which have seen rapid uptake in this market space. Mobile health or mHealth can be said to be an outcome of this convergence of technological advancements and the ongoing effort towards overhauling the healthcare industry. mHealth technologies have shown they have the potential to address key shortcomings in healthcare delivery. They have proven effective in the remote monitoring and management of chronic illnesses, in the emergence of consumer-centric medical care and in the reduction of overall health expenses. Governments all around the world have gauged the potential of this technology and have adopted it to implement public health pilots and small-scale projects. Public health systems have resorted to mHealth to drive new initiatives in promoting connected healthcare delivery and management. For instance, mHealth has been used in minimizing the burden imposed on economic and healthcare resources by chronic conditions such as diabetes, obesity, hypertension and the rapidly aging population. Amongst other key healthcare stakeholders, providers see mHealth technologies as a means of improving their productivity and enhancing care-coordination among physicians and patients. Consumers, on the other hand, have consciously or unconsciously resorted to mHealth to fill gaps in care and integrate their health choices with their lifestyle. A successful health technology at the convenience of the consumer’s hands is proposition for a profitable business opportunity for vendors. Increasing product development activity, market consolidation and the emergence of health- related business ventures demonstrate the impact of mHealth on vendors in the healthcare spectrum. Key players in the telecom and Information Technology (IT) sectors have only recently entered this emerging and significant potential market space. Technology start-ups and venture capital firms have also exhibited interest in capitalizing on opportunities in this market. Given these trends, the mHealth market is expected to significantly revolutionize health care delivery and management in the future.

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GDME0156MAR / Published APR 2012 Page 1 Mobile Health Devices and Applications - Global Market Briefing

to 2018 © GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form

Mobile Health Devices and Applications - Global Market Briefing to 2018

Reference Code: GDME0156MAR Publication Date: April 2012

The Global Market for Mobile Health (mHealth) is Forecast to Grow at a Compound Annual Growth Rate (CAGR) of XX% from 2010-2018

mHealth Market, Global, Revenue ($bn), 2010-2018

2010 2018

Rev

enue

($bn

)

CAGR(2010-2018): XX%

Source: GlobalData, Annual Reports, SEC Filings, Investor Presentations, Earning Call Transcripts, News and Press Releases, Scientific Journals, Trade Associations, Interviews with Industry Experts and Key Opinion Leaders (KOLs)

The global market for Mobile Health (mHealth) technology, estimated to be valued at about $XX billion in 2010, is forecast to grow at a Compound Annual Growth Rate (CAGR) of XX% to exceed $XX billion by 2018. This market includes mHealth devices and peripherals and mHealth applications and services. The exponential growth of this market can be attributed to the significant impetus provided by stakeholders across the healthcare spectrum. Mobile technologies have shown in recent years to be capable of enhancing healthcare delivery and management while limiting the burden they impose on the economy. They have been proven to improve patient and physician convenience, enable remote monitoring and improvise care-coordination among providers, patients, public health systems and payors.

The Rapid Emergence of Mobile Health (mHealth) Technology is Expected to Revolutionize Health Delivery and Management in the Future

The use of mobile technology to enhance healthcare delivery and management has evolved significantly in the past five to seven years. During this period, the adoption of mobile technology in all facets of day-to-day life as well as business activities has emerged rapidly. On the other hand, the same period saw the global healthcare industry address concerns related to cost efficiency, improvement in clinical outcomes and

expansion of access to care through the adoption of advanced technologies.

The digitalization of medical information and exchange of this information through a connected healthcare infrastructure are key changes which have seen rapid uptake in this market space. Mobile health or mHealth can be said to be an outcome of this convergence of technological advancements and the ongoing effort towards overhauling the healthcare industry.

mHealth technologies have shown they have the potential to address key shortcomings in healthcare delivery. They have proven effective in the remote monitoring and management of chronic illnesses, in the emergence of consumer-centric medical care and in the reduction of overall health expenses. Governments all around the world have gauged the potential of this technology and have adopted it to implement public health pilots and small-scale projects. Public health systems have resorted to mHealth to drive new initiatives in promoting connected healthcare delivery and management. For instance, mHealth has been used in minimizing the burden imposed on economic and healthcare resources by chronic conditions such as diabetes, obesity, hypertension and the rapidly aging population.

Amongst other key healthcare stakeholders, providers see mHealth technologies as a means of improving their productivity and enhancing care-coordination among physicians and patients. Consumers, on the other hand, have consciously or unconsciously resorted to mHealth to fill gaps in care and integrate their health choices with their lifestyle.

A successful health technology at the convenience of the consumer’s hands is proposition for a profitable business opportunity for vendors. Increasing product development activity, market consolidation and the emergence of health-related business ventures demonstrate the impact of mHealth on vendors in the healthcare spectrum. Key players in the telecom and Information Technology (IT) sectors have only recently entered this emerging and significant potential market space. Technology start-ups and venture capital firms have also exhibited interest in capitalizing on opportunities in this market.

Given these trends, the mHealth market is expected to significantly revolutionize health care delivery and management in the future.

GDME0156MAR / Published APR 2012 Page 2 Mobile Health Devices and Applications - Global Market Briefing

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1 Table of Contents 1 Table of Contents ............................................................................................................................ 2

1.1 List of Tables............................................................................................................................. 3 1.2 List of Figures............................................................................................................................ 3

2 Mobile Health Devices and Applications ........................................................................................... 4 2.1 Introduction ............................................................................................................................... 4 2.2 Mobile Health, Global Market Characterization ........................................................................... 6

2.2.1 Mobile Health Market, Global, Revenue ($bn), 2010-2018.................................................. 6 2.2.2 Mobile Health Market, the US, Revenue ($bn), 2010-2018................................................. 7

2.3 Mobile Health, Global, Market Dynamics .................................................................................... 8 2.3.1 Market Drivers.................................................................................................................. 8 2.3.2 Market Restraints ........................................................................................................... 15

2.4 Key Players and mHealth Products .......................................................................................... 17 2.5 Key Deals ............................................................................................................................... 20

3 Appendix....................................................................................................................................... 22 3.1 Definitions............................................................................................................................... 22

3.1.1 Mobile Health (mHealth) ................................................................................................. 22 3.2 Acronyms................................................................................................................................ 23 3.3 Sources .................................................................................................................................. 24 3.4 Research Methodology............................................................................................................ 24 3.5 Secondary Research ............................................................................................................... 25 3.6 Primary Research.................................................................................................................... 25 3.7 Models.................................................................................................................................... 25 3.8 Forecasts................................................................................................................................ 26 3.9 Expert Panels.......................................................................................................................... 26 3.10 GlobalData Consulting............................................................................................................. 26 3.11 Contact Us .............................................................................................................................. 26 3.12 Disclaimer ............................................................................................................................... 26

GDME0156MAR / Published APR 2012 Page 3 Mobile Health Devices and Applications - Global Market Briefing

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1.1 List of Tables Table 1: Mobile Health Market, Global, Revenue ($bn), 2010-2018* .................................................... 6 Table 2: Mobile Health Market, The US, Revenue ($bn), 2010-2018*................................................... 7 Table 3: Remote Patient Monitoring Market, Global, by Segment, Revenue ($m), 2004-2018............... 8 Table 4: Venture Capital Investments in Mobile Health ($m), 2010-2011............................................ 14 Table 5: Mobile Health Ventures of Key Players in the Medical Imaging Information Systems (MIS)

Market, 2011 ...................................................................................................................... 17 Table 6: Number of Health Applications, by Vendor Store, 2010 ........................................................ 18 Table 7: Top Health Apps, Apple App Store, 2011............................................................................. 19 Table 8: Mobile Health Market, Key Deals, 2011-2012* ..................................................................... 20

1.2 List of Figures Figure 1: Mobile Health, Market Overview............................................................................................ 4 Figure 2: Mobile Health Market, Global, Revenue ($bn), 2010-2018* .................................................... 6 Figure 3: Mobile Health Market, The US, Revenue ($bn), 2010-2018*................................................... 7 Figure 4: Remote Patient Monitoring Market, Global, by Segment, Revenue ($m), 2004-2018............... 8 Figure 5: Physician Interest In Mobile Technology, By Provider*, 2011................................................ 10 Figure 6: Total Wireless Broadband Subscriptions, The US and Global*, 2010-2011 ........................... 11 Figure 7: Wireless Broadband Subscriptions, by Technology, Global*, June 2011 ............................... 12 Figure 8: Venture Capital Investments in Mobile Health, Net Value ($m), 2010-2011 ........................... 14 Figure 9: Key Barriers to Mobile Technology in Healthcare, 2011........................................................ 16 Figure 10: Number of Health Applications, by Vendor Store, 2010 ........................................................ 18

GDME0156MAR / Published APR 2012 Page 4 Mobile Health Devices and Applications - Global Market Briefing

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2 Mobile Health Devices and Applications

2.1 Introduction Mobile Health, or mHealth refers to the utilization of portable technologies for the purpose of healthcare delivery and/or management. These technologies generally require a hand-held device such as a smartphone, a tablet or a wireless-enabled monitor/sensor. mHealth technologies can refer to products or services, and range from portable ECG monitors to web-based fitness and health applications or SMS-based management of treatment plans for chronic conditions.

At the 2010 mHealth summit of the Foundation for the National Institutes of Health (FNIH), mHealth was defined as “the delivery of healthcare services via mobile communication devices”. According to the World Health Organization (WHO) Global Observatory for eHealth (GOe), mHealth can be defined as “medical and public health practice supported by mobile devices, such as mobile phones, patient monitoring devices, Personal Digital assistants (PDAs), and other wireless devices”.

The 2011 mHealth summit of the FNIH demonstrated that mHealth, as a delivery mechanism is rapidly pushing the penetration of affordable healthcare access to larger segments of the population. At the same time, mHealth is also enhancing the capacity of public health systems to provide quality healthcare. As emphasized om the WHO’s GOe mobile health survey, mHealth necessitates connectivity of hand-held devices with core connectivity-based services such as General Packet Radio Services (GPRS), third and fourth generation mobile telecommunications (3G and 4G systems), Wi-Fi, Global Positioning Systems (GPS), or Bluetooth technology.

Since mHealth essentially requires a simple hand held device, it outscores several alternate consumer-centric channels for healthcare delivery. The viability of this technology lies in that it virtually connects stakeholders across the healthcare market space, including public health systems, providers, payors and vendors, with their consumers.

Figure 1: Mobile Health, Market Overview

Device Examples

-Portable hand-held monitoring devices such as ECG heart monitors, pocket-sized ultrasound devices

-Embedded sensor-based devices and peripherals such as arm bands, smart shirts. These usually connect to smartphones/tablets through applications

mHealth Market

mHealth Devices and Peripherals

mHealth Applications (Apps) and Services

Consumer-Oriented Mobile Apps

Medical Professional Oriented Mobile Apps

Apps Examples

-Patient communicator-based services

-Apps to connect with electronic medical records and image management systems

-Apps for remote diagnosis and consultation

-Clinical decision support-based apps

Apps Examples

-Fitness and wellness apps

-Clinical information-based apps such as assessment of symptoms

-Scheduling and appointment apps

-Medication adherence apps

-Chronic condition or monitoring apps

Source: GlobalData, Interviews with Industry Experts and Key Opinion Leaders (KOLs)

GDME0156MAR / Published APR 2012 Page 7 Mobile Health Devices and Applications - Global Market Briefing

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2.2.2 Mobile Health Market, the US, Revenue ($bn), 2010-2018

Figure 3: Mobile Health Market, The US, Revenue ($bn), 2010-2018*

2010 2011 2012 2013 2014 2015 2016 2017 2018

Rev

enue

($bn

)

Source: GlobalData, Annual Reports, SEC Filings, Investor Presentations, Earning Call Transcripts, News and Press Releases, Scientific Journals, Trade Associations, Interviews with Industry Experts and Key Opinion Leaders (KOLs) *- Market Sizing data from 2012-2018 are estimated forecasts

Table 2: Mobile Health Market, The US, Revenue ($bn), 2010-2018*

2010 2011 2012 2013 2014 2015 2016 2017 2018 CAGR (2010-2018)

mHealth Market

Source: GlobalData, Annual Reports, SEC Filings, Investor Presentations, Earning Call Transcripts, News and Press Releases, Scientific Journals, Trade Associations, Interviews with Industry Experts and Key Opinion Leaders (KOLs) *- Market Sizing data from 2012-2018 are estimated forecasts

The US mHealth market, valued at approximately $XX billion in 2010 is forecast to grow at a CAGR of about XX% during the period 2010-2018, to exceed $XX billion by 2018. Favorable growth prospects in this region can be attributed to the ongoing healthcare reforms and the mounting pressure to improve cost efficiency in healthcare delivery and offer enhanced outcomes. mHealth is expected to enable the US federal agencies to build a platform for connected, consumer-centric healthcare, while allowing them to control the ever-increasing government expenditure in this domain. In addition, the proliferation of baby boomers and a growing patient-base with chronic diseases such as diabetes will continue to enhance the demand for mHealth in this region.

The US currently attributes to about 60% of the global mHealth market. Although this market is poised to grow at a substantial rate, the penetration of mHealth technologies in alternate geographies is expected to bring this share down to XX% by 2016.

GDME0156MAR / Published APR 2012 Page 8 Mobile Health Devices and Applications - Global Market Briefing

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2.3 Mobile Health, Global, Market Dynamics 2.3.1 Market Drivers 2.3.1.1 Mobile Health Technologies Enhance Remote Patient Monitoring and Management;

Push Patient and Provider Adoption

mHealth is expected to enhance quality of care by enabling targeted, timely care based on real-time collection and/or communication of relevant health data, as well as new care possibilities that are enabled through continuous monitoring, wireless communication and/or rich new databases of disease conditions. Approximately XX% of healthcare spending is on patients suffering from one or more chronic diseases, namely diabetes, obesity, heart disease, lung disease, high blood pressure and cancer. Using mHealth solutions to monitor these chronic-disease patients improves disease management, which improves patients’ quality of life and reducing the need for hospital visits.

Figure 4: Remote Patient Monitoring Market, Global, by Segment, Revenue ($m), 2004-2018

2004 2011 2018

Rev

enue

($m

)

External Remote Patient Monitoring Devices Implantable Remote Patient Monitoring Devices

Source: GlobalData, Annual Reports, SEC Filings, Investor Presentations, Earning Call Transcripts, News and Press Releases, Scientific Journals, Trade Associations, Interviews with Industry Experts and Key Opinion Leaders (KOLs)

Table 3: Remote Patient Monitoring Market, Global, by Segment, Revenue ($m), 2004-2018

2004 2011 2018 CAGR (2004-2011)

CAGR (2011-2018)

External Remote Patient Monitoring Devices

Implantable Remote Patient Monitoring Devices

Source: GlobalData, Annual Reports, SEC Filings, Investor Presentations, Earning Call Transcripts, News and Press Releases, Scientific Journals, Trade Associations, Interviews with Industry Experts and Key Opinion Leaders (KOLs)

GDME0156MAR / Published APR 2012 Page 10 Mobile Health Devices and Applications - Global Market Briefing

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2.3.1.2 Improved Patient and Physician Convenience and Wider Healthcare Access Drive the Need for Mobile Health

Mobile health has proven to be a competent technology to address key concerns regarding healthcare delivery associated with patient and physician convenience. Simultaneously, the adoption of mHealth also expands the outreach of quality healthcare access to larger, under-served segments of the population. These capabilities drive the need to adopt and efficiently implement mHealth technologies.

Improving Physician and Patient Convenience

Figure 5: Physician Interest In Mobile Technology, By Provider*, 2011

Many Clinicians Express Interest

Few Clinicians Express Interest

Don't KnowNo Clinicians Express

Interest

Source: GlobalData, HIMSS Mobile Technology Survey 2011 * - About 164 Respondents (Provider Organizations/ Facilities)

According to a 2011 mobile technology survey conducted by the Healthcare Information and Management Systems Society (HIMSS), as many as XX% of the provider organizations/facilities responding to the survey claimed that a majority of their clinicians are interested to use mHealth technologies. Convenience in handling large patient volumes and the ability to delivery faster healthcare through the instant access to patient health information were cited by clinicians as major reasons to adopt mHealth technologies. While these technologies play a significant role in physician convenience, they also assist in enhancing patient convenience and expanding the outreach of healthcare.

Mobile health solutions intrinsically enhance patient-physician engagement and connectivity. By enhancing the provision of consumer-centric health care, mHealth technologies allow physicians to improve productivity. The ability to engage with their patients remotely through their smartphones and tablets allow clinicians to cater to a larger population conveniently. Moreover, access to rich databases, clinical decision support systems and case-based reasoning systems allow clinicians to treat patients while continuing with their own lifestyles. The importance of mobile health technologies is also substantiated by the growing disproportion between the growing patient population and the number of physicians.

GDME0156MAR / Published APR 2012 Page 22 Mobile Health Devices and Applications - Global Market Briefing

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3 Appendix The data and analysis within this report is driven by Medical eTrack

Medical eTrack gives you the key information to drive sales, investment and deal making activity in your business. It includes the following information:

15,000+ Market size data tables across 740 medical equipment segments and 39 countries with historic data from 2004 forecast to 2018

6,000+ Primary expert interviews conducted per annum for ensuring data and report quality

1,100+ Conferences on medical equipment covered

1,000+ Industry leading reports per annum covering growing sectors, market trends, investment opportunities and competitive landscape

600+ Analysis reports covering market and pipeline product analysis reports by indication, medical equipment trends and issue reports and investment and M&A trend reports worth over $3 Million

43,000+ Medical equipment companies profiled

1,500+ Private, emerging and technology start-up company profiles

1,500+ Medical equipment manufacturers in China and India

1,500+ Medical equipment companies in Japan

700+ Companies with revenue splits and market shares by category

1,500+ Quarterly and annual medical equipment company financials

700+ Medical equipment company SWOT’s

9,000+ Pipeline product profiles

8,000+ Marketed product profiles

14,000+ Clinical trials

15,000+ Trial investigators

13,000+ New product patents

3,300+ Companies with products in development

17,000+ Deals in the medical equipment industry

1,100+ Surgical and diagnostic procedures by therapy area

40+ Key healthcare indicators by country

For more information or to receive a free demo of the service visit http://www.medicaletrack.com/contactus.aspx?RD=Demo=

3.1 Definitions 3.1.1 Mobile Health (mHealth) Mobile Health or mHealth refers to the utilization of portable technologies for the purpose of healthcare delivery and/or management. mHealth technologies can refer to products or services and range from portable ECG monitors to web-based fitness and health applications or SMS-based management of treatment plans for chronic conditions.

3.1.1.1 mHealth Devices and Peripherals

mHealth devices and peripherals refer to a wide range of portable, pocket-sized devices or sensors which can be used for point-of-care diagnosis, monitoring and medical management. These devices are equipped with some kind of broadband connectivity such as wireless or Bluetooth connectivity.

GDME0156MAR / Published APR 2012 Page 23 Mobile Health Devices and Applications - Global Market Briefing

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3.1.1.2 mHealth Applications and Services

mHealth apps and services are software applications and broadband-based services which may assist in healthcare delivery and consumer-centric health management. mHealth applications can be consumer-oriented or medical professional oriented; whereas mHealth services include SMS/MMS based broadband-communication services.

3.2 Acronyms ACO: Accountable Care Organizations

App: Application

CAGR: Compounded Annual Growth Rate

CMS: Center for Medicare and Medicaid Services

EHR: Electronic Health Record

e-PHI: electronic Protected Health Information

EU: European Union

FDA: Food and Drug Administration

GOe: Global Observatory for eHealth

GPS: Global Positioning System

HHS: Department of Human and Health Services

HIE: Health Information Exchange

HIMSS: Healthcare Information and Management Systems Society

HIPAA: Health Insurance Portability and Accountability Act

HIS: Hospital Information System

IT: Information Technology

mHealth: Mobile Health

MHRA: Medicines and Healthcare products Regulatory Agency

NIH: National Institute of Health

PACS: Picture Archiving and Communication Systems

PDA: Personal Digital Assistants

RPM: Remote Patient Monitoring

R&D: Research and Development

RSNA: Radiological Society of North America

GDME0156MAR / Published APR 2012 Page 24 Mobile Health Devices and Applications - Global Market Briefing

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3.3 Sources Government Sources, Journals and Trade Publications

Healthcare Information and Management Systems Society (2011). HIMSS 2011 Mobile Technology Survey - December 2011. Available from: http://www.mhimss.org/resource/2011-mhimss-mobile-technology-survey (Accessed date: March 6, 2012)

World Health Organization (2011). Global Observatory for eHealth, Publications Volume 1-3 - June 2011. Available from: http://www.who.int/goe/en/ (Accessed date: March 7, 2012)

Rick Krohn, David Metcalf (2012). mHealth: From Smartphones to Smart Systems - January 2012. Available from: http://www.mhimss.org/resource/mhealth-smart-phones-smart-systems (Accessed Date: March 7, 2012)

Organization for Economic Co-operation and Development (2011). OECD Broadband Portal - June 2010-2011. Available from: http://www.oecd.org/sti/ict/broadband (Accessed Date: March 19, 2012)

Company Websites, Annual Reports, Quarterly Reports, SEC Filings, Investor Presentations, Product Websites GE Healthcare. Available from: www.gehealthcare.com/

Siemens Healthcare. Available from: www.medical.siemens.com/

Cerner Corporation. Available from: www.cerner.com/

Allscripts Healthcare Solutions. Available from: www.allscripts.com/

Apple Corporation. Available from: http://www.itunes.com/appstore

Intel Corporation. Available from: http://www.intel.com/about/companyinfo/healthcare/index.htm

Google, Inc. Available from: https://play.google.com/store

Online Sources:

Healthcare IT News. Available from: http://www.healthcareitnews.com

mHIMSS. Available from: http://www.mhimss.org/

Healthcare Finance News. Available from: http://www.healthcarefinancenews.com

Mobile Health Watch. Available from: http://www.mhealthwatch.com

MobiThinking. Available from: http://mobithinking.com/

iMedicalApps. Available from: www.imedicalapps.com/

Fierce Mobile Healthcare. Available from: www.fiercemobilehealthcare.com

Information Week. Available from: www.informationweek.com

Mobile Health Insight. Available from: http://www.mhealthinsight.com

EHR Watch. Available from: http://www.ehrwatch.com/

3.4 Research Methodology GlobalData’s dedicated research and analysis teams consists of qualified professionals with experience in marketing, market research, consulting background in the medical devices industry and advanced statistical expertise.

GlobalData adheres to the codes of practice of the Market Research Society (www.mrs.org.uk) and the Society of Competitive Intelligence Professionals (www.scip.org).

All GlobalData databases are continuously updated and revised. The following research methodology is followed for all databases and reports.

GDME0156MAR / Published APR 2012 Page 25 Mobile Health Devices and Applications - Global Market Briefing

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3.5 Secondary Research The research process begins with exhaustive secondary research on internal and external sources being carried out to source qualitative and quantitative information relating to each market.

The secondary research sources that are typically referred to include, but are not limited to:

Company websites, annual reports, financial reports, broker reports, investor presentations and SEC Filings;

Company websites, annual reports, financial reports, broker reports, investor presentations and SEC Filings;

Industry trade journals, scientific journals and other technical literature;

Internal and external proprietary databases;

Relevant patent and regulatory databases;

National government documents, statistical databases and market reports;

Procedure registries; and

News articles, press releases and web-casts specific to the companies operating in the market.

3.6 Primary Research GlobalData conducts hundreds of primary interviews a year with industry participants and commentators in order to validate its data and analysis. A typical research interview fulfills the following functions:

It provides first-hand information on market size, market trends, growth trends, competitive landscape and future outlook;

Helps in validating and strengthening the secondary research findings; and

Further develops the analysis team’s expertise and market understanding.

Primary research involves e-mail interactions, telephonic interviews as well as face-to-face interviews for each market, category, segment and sub-segment across geographies.

The participants who typically take part in such a process include, but are not limited to:

Industry participants: CEOs, VPs, marketing/product managers, market intelligence managers and national sales managers;

Hospital stores, laboratories, pharmacies, distributors and paramedics;

Outside experts: investment bankers, valuation experts, research analysts specializing in specific medical equipment markets; and

Key opinion leaders: physicians and surgeons specializing in different therapeutic areas corresponding to different kinds of medical equipment.

3.7 Models Where no hard data is available, GlobalData uses modeling and estimates in order to produce comprehensive data sets. The following rigorous methodology is adopted:

Available hard data is cross-referenced with the following data types to produce estimates on:

Demographic data on population segments;

Macro-economic indicators such as GDP, inflation rate;

Healthcare indicators such as health expenditure, physician base, healthcare infrastructure and facilities; and

Selected epidemiological and procedure statistics.

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3.8 Forecasts GlobalData uses proprietary forecast models. The following four factors are utilized in the forecast models:

Historic growth rates;

Macro-indicators such as population trends and healthcare spending;

Forecast epidemiological data; and

Qualitative trend information and assumptions.

The data is then cross-checked by the expert panel.

3.9 Expert Panels GlobalData uses a panel of experts to cross-verify its databases and forecasts.

GlobalData’s expert panel comprises marketing managers, product specialists, international sales managers from medical device companies; academics from research universities, KOLs from hospitals, consultants from venture capital funds and distributors/suppliers of medical equipment and supplies etc.

Historic data and forecasts are relayed to GlobalData’s expert panel for feedback and adjusted in accordance with their feedback.

3.10 GlobalData Consulting We hope that the data and analysis in this brief will help you make informed and imaginative business decisions. If you have further requirements, GlobalData’s consulting team may be able to help you. GlobalData offers tailor-made analytical and advisory services to drive your key strategic decisions.

3.12 Disclaimer All Rights Reserved.

No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form by any means, electronic, mechanical, photocopying, recording or otherwise without the prior permission of the publisher, GlobalData.