GCN4 SM SIR1 Hughes00 10.2 6.27E-11 188 · SKN7_H2O2Losas3D_taf1-ts2Durant06 9.21 6.07E-10 163 UME6_H2O2Hiume6_del Bernstein_00_affydeletions9.2 6.18E-10 98 GCN4_SM swi1_rich_medium_experimentSudarsanam00

TF Cohort NameCondition NamePublication NameKS score KS p-value Cohort SizeGCN4_SM SIR2 Hughes00 50.47 3.32E-51 189GCN4_RAPA HDA1 Hughes00 44.05 8.77E-45 160GCN4_SM HDA1 Hughes00 43.97 1.05E-44 189GCN4_RAPA SIR2 Hughes00 42.63 2.34E-43 160GCN4_RAPA ISW2 Hughes00 31.08 8.16E-32 159GCN4_SM SIR3 Hughes00 30.81 1.54E-31 189GCN4_SM ISW2 Hughes00 30.02 9.48E-31 188GCN4_RAPA SIR4 Hughes00 29.66 2.18E-30 160GCN4_SM SIR4 Hughes00 28.53 2.94E-29 189GCN4_YPD SIR2 Hughes00 27.09 8.00E-28 75GCN4_RAPA SIR3 Hughes00 27.08 8.15E-28 159GCN4_YPD HDA1 Hughes00 25.18 6.48E-26 74GCN4_SM HIR2 Hughes00 24.83 1.47E-25 189GCN4_RAPA HIR2 Hughes00 22.16 6.84E-23 160GCN4_SM HST3 Hughes00 21.68 2.08E-22 188NRG1_YPD TUP1_haploid Hughes00 20.86 1.35E-21 72GCN4_RAPA HST3 Hughes00 20.66 2.16E-21 160GCN4_SM ubp10sir4 Orlandi04 -20.55 2.76E-21 155HSF1_H2O2Hi DT_Null Chitikila_02 20.29 5.09E-21 118GCN4_RAPA ino80_+_0.1%_MMS_vs._ino80Attikum04 20.27 5.33E-21 142SWI4_YPD esa1-414 Durant06 19.66 2.16E-20 142GCN4_YPD ISW2 Hughes00 19.58 2.63E-20 74HSF1_H2O2LoDT_Null Chitikila_02 19.31 4.80E-20 97YAP7_H2O2Lo ino80_+_0.1%_MMS_vs._ino80Attikum04 18.57 2.68E-19 132NRG1_H2O2HiSSN6_haploid Hughes00 18.16 6.80E-19 122RPN4_H2O2Lospt3 Huisinga04 17.93 1.16E-18 95GCN4_YPD SIR4 Hughes00 17.68 2.05E-18 75NRG1_H2O2HiTUP1_haploid Hughes00 17.51 3.03E-18 123GCN4_SM Dpho23 Keogh05 17.34 4.48E-18 185GCN4_RAPA ubp10sir4 Orlandi04 -17.17 6.76E-18 126YAP7_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 16.88 1.29E-17 126GCN4_YPD SIR3 Hughes00 16.72 1.87E-17 75GCN4_RAPA arp8_+_0.1%_MMS_vs._arp8Attikum04 16.44 3.55E-17 145PHD1_BUT90 TUP1_haploid Hughes00 16.17 6.63E-17 106GCN4_YPD HIR2 Hughes00 15.92 1.20E-16 75GCN4_RAPA SWD2 Mnaimneh_04 15.91 1.21E-16 160YAP6_YPD TUP1_haploid Hughes00 15.86 1.37E-16 91GCN4_RAPA ume6 Fazzio01 15.85 1.41E-16 155HSF1_H2O2Hi esa1-414 Durant06 15.65 2.22E-16 113GCN4_SM ino80_+_0.1%_MMS_vs._ino80Attikum04 15.49 3.21E-16 165PHD1_BUT90 SSN6_haploid Hughes00 15.21 6.04E-16 105SKN7_H2O2Loesa1-414 Durant06 15.13 7.37E-16 174RIM101_H2O2LoTUP1_haploid Hughes00 15.02 9.35E-16 53GCN4_SM SWD2 Mnaimneh_04 15.01 9.76E-16 189CIN5_H2O2Lo TUP1_haploid Hughes00 14.84 1.43E-15 126GCN4_SM ISW1_ISW2 Hughes00 14.81 1.52E-15 189CIN5_YPD SSN6_haploid Hughes00 14.61 2.40E-15 149NRG1_YPD SSN6_haploid Hughes00 14.37 4.25E-15 72GCN4_RAPA SPT8 Ingvarsdottir05 14.11 7.67E-15 144SOK2_BUT14 SSN6_haploid Hughes00 14 9.95E-15 72HSF1_H2O2Lohtz1_sir2 Meneghini03 13.97 1.07E-14 100RPN4_H2O2Loino80_+_0.1%_MMS_vs._ino80Attikum04 13.54 2.86E-14 85

GCN4_SM IOC4 Hughes00 -13.46 3.41E-14 188YAP7_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 13.23 5.85E-14 125GCN4_SM esa1-414 Durant06 13.1 7.81E-14 173GCN4_SM ume6 Fazzio01 13.01 9.59E-14 183GCN4_RAPA ISW1_ISW2 Hughes00 13.01 9.67E-14 160GCN4_SM Drxt1 Keogh05 13.01 9.76E-14 187GCN4_SM SPT8 Ingvarsdottir05 12.93 1.15E-13 171HAP4_YPD DT_V161R_L Chitikila_02 -12.78 1.65E-13 66UME6_YPD ume6 Fazzio01 12.72 1.89E-13 125SOK2_BUT14 TUP1_haploid Hughes00 12.51 3.08E-13 72GCN4_RAPA Dpho23 Keogh05 12.48 3.28E-13 158ABF1_YPD EAF5 Krogan04 -12.47 3.32E-13 241HAP1_YPD esa1-414 Durant06 12.4 3.91E-13 138SKN7_H2O2LoWT_V161E Chitikila_02 -12.36 4.27E-13 166YAP7_H2O2Lo arp8_+_0.1%_MMS_vs._arp8Attikum04 12.33 4.61E-13 130HAP4_YPD hht2_K4G Martin04 12.27 5.36E-13 53CIN5_H2O2Lo SSN6_haploid Hughes00 12.24 5.75E-13 124RIM101_H2O2LoSSN6_haploid Hughes00 12.23 5.85E-13 53HSF1_H2O2Hi WT_TAF1_GCN5Huisinga04 -12.19 6.39E-13 121CIN5_YPD TUP1_haploid Hughes00 12.17 6.61E-13 150GCN4_YPD ubp10sir4 Orlandi04 -12.1 7.88E-13 62GCN4_RAPA PCH1 Hughes00 12.03 9.20E-13 155SUT1_YPD TUP1_haploid Hughes00 11.96 1.09E-12 69GCN4_SM arp8_+_0.1%_MMS_vs._arp8Attikum04 11.81 1.52E-12 166YAP6_H2O2Lo TUP1_haploid Hughes00 11.77 1.66E-12 57GCN4_YPD HST3 Hughes00 11.75 1.76E-12 75ASH1_BUT14 esa1-414 Durant06 11.63 2.30E-12 45GCN4_RAPA HAT2 Hughes00 -11.59 2.57E-12 160SKN7_H2O2LoWT_V71R Chitikila_02 -11.57 2.64E-12 163GCN4_RAPA IOC4 Hughes00 -11.57 2.66E-12 159MSN2_H2O2Hitaf1-ts2_gcn5 Huisinga04 11.55 2.80E-12 76HSF1_H2O2Loesa1-414 Durant06 11.54 2.86E-12 92PHD1_YPD SSN6_haploid Hughes00 11.47 3.35E-12 67SUT1_YPD SSN6_haploid Hughes00 11.44 3.58E-12 69HSF1_H2O2Hi htz1_sir2 Meneghini03 11.42 3.80E-12 123PHD1_YPD TUP1_haploid Hughes00 11.36 4.36E-12 67UME6_YPD rpd3_H3dN_v_H3dNSabet04 11.27 5.28E-12 129SKN7_H2O2LoTUP1_haploid Hughes00 11.24 5.64E-12 183SWI6_YPD esa1-414 Durant06 11.17 6.68E-12 142GCN4_SM ubp10 Orlandi04 -11.14 7.12E-12 150SKN7_H2O2LoSSN6_haploid Hughes00 10.92 1.19E-11 184GCN4_RAPA ubp10 Orlandi04 -10.91 1.23E-11 121HSF1_H2O2Hi htz1_del Mizuguch04 10.9 1.25E-11 124YAP6_YPD SSN6_haploid Hughes00 10.87 1.32E-11 91SKN7_H2O2Loesa1-414_taf1-ts2Durant06 10.84 1.44E-11 171HAP4_YPD taf1-ts2_25C Huisinga04 10.75 1.75E-11 63GCN4_RAPA swi1_rich_medium_experimentSudarsanam00 10.71 1.91E-11 160SKN7_H2O2LoVID21 Krogan04 10.69 2.01E-11 161SKN7_H2O2LoARP4 Mnaimneh_04 10.61 2.43E-11 186HSF1_H2O2Lohtz1_del Mizuguch04 10.55 2.81E-11 101GCN4_RAPA 0.1%_MMS Attikum04 10.51 3.03E-11 144SKN7_H2O2LoWT_V161R_K Chitikila_02 -10.34 4.50E-11 167MBP1_H2O2Higcn5 Huisinga04 -10.27 5.34E-11 128

GCN4_SM SIR1 Hughes00 10.2 6.27E-11 188GCN4_SM esa1-414_taf1-ts2Durant06 10.18 6.52E-11 177GCN4_SM Dsin3 Keogh05 10.15 6.96E-11 155SKN7_H2O2Lotaf1-ts2_GCN5Huisinga04 10.03 9.25E-11 171MBP1_H2O2Hi esa1-414 Durant06 9.99 1.01E-10 122SWI4_YPD WT_N69S Chitikila_02 -9.97 1.07E-10 143RPN4_H2O2Lohat1D_taf1-ts2Durant06 9.95 1.12E-10 89MSN2_H2O2Hiesa1-414_taf1-ts2Durant06 9.89 1.27E-10 72SKN7_H2O2LoEPL1 Mnaimneh_04 9.88 1.29E-10 186RPN4_H2O2Lohtz1_sir2 Meneghini03 9.82 1.49E-10 98SKN7_H2O2HiSSN6_haploid Hughes00 9.69 2.01E-10 97GCN4_YPD IOC4 Hughes00 -9.66 2.16E-10 75MSN2_H2O2Hisas3D_taf1-ts2Durant06 9.59 2.53E-10 73GCN4_SM PCH1 Hughes00 9.5 3.10E-10 185SWI4_YPD gcn5 Huisinga04 -9.5 3.14E-10 151HAP4_YPD hht2_K27G Martin04 9.5 3.16E-10 54MBP1_H2O2HiRPD3_haploid Hughes00 9.47 3.34E-10 133HAP4_YPD IES6 Hughes00 9.45 3.51E-10 67HSF1_H2O2Hi WT_TAF1_SPT3Huisinga04 -9.36 4.36E-10 122HAP4_YPD Rpd3_del Bernstein02 -9.31 4.80E-10 67UME6_H2O2Hirpd3_H3dN_v_H3dNSabet04 9.31 4.86E-10 99SWI4_YPD WT_N69R Chitikila_02 -9.3 5.01E-10 144NRG1_YPD Set1_del Bernstein02 9.29 5.02E-10 72HAP4_YPD isw2_sin3 Fazzio01 -9.25 5.60E-10 64SKN7_H2O2Losas3D_taf1-ts2Durant06 9.21 6.07E-10 163UME6_H2O2Hiume6_del Bernstein_00_affydeletions9.2 6.18E-10 98GCN4_SM swi1_rich_medium_experimentSudarsanam00 9.19 6.33E-10 189SKN7_YPD VID21 Krogan04 9.18 6.55E-10 60GCN4_SM Drpd3 Keogh05 9.16 6.77E-10 177MSN2_H2O2Hitaf1-ts2_GCN5Huisinga04 9.15 7.01E-10 74MBP1_H2O2HiHDA1 Hughes00 -9.14 7.14E-10 133RCS1_H2O2Lospt3 Huisinga04 9.13 7.34E-10 241SUM1_YPD rpd3_c.i. Fazzio01 -9.11 7.63E-10 59UME6_H2O2HiDsds3 Keogh05 9.1 7.84E-10 92SKN7_H2O2LoYNG2 Mnaimneh_04 9.04 8.95E-10 186YAP6_YPD Hda1_del Bernstein02 9.03 9.15E-10 90SWI6_YPD gcn5 Huisinga04 -8.97 1.07E-09 149HAP4_YPD WT_V71R Chitikila_02 -8.93 1.16E-09 63SKN7_H2O2LoWT_V71E Chitikila_02 -8.93 1.17E-09 155GCN4_YPD SPT8 Ingvarsdottir05 8.91 1.23E-09 65GCN4_YPD swi1_rich_medium_experimentSudarsanam00 8.91 1.23E-09 75MBP1_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 8.86 1.37E-09 126HSF1_H2O2Hi DT_WT Chitikila_02 8.82 1.51E-09 118SKN7_H2O2Logcn5D_taf1-ts2Durant06 8.8 1.55E-09 164GCN4_YPD HAT2 Hughes00 -8.8 1.57E-09 75CIN5_H2O2Hi TUP1_haploid Hughes00 8.78 1.65E-09 79PHD1_BUT90 Hda1_del Bernstein02 8.77 1.67E-09 105GCN4_RAPA esa1-414 Durant06 8.74 1.81E-09 150YAP6_H2O2Lo SSN6_haploid Hughes00 8.7 1.99E-09 57SKN7_H2O2LoWT_N69R Chitikila_02 -8.69 2.03E-09 166MSN4_H2O2Higcn5D_taf1-ts2Durant06 8.67 2.10E-09 66YAP7_H2O2Hi 0.1%_MMS Attikum04 8.67 2.10E-09 126UME6_H2O2Hiume6 Fazzio01 8.64 2.24E-09 98

UME6_YPD isw2_ume6 Fazzio01 8.6 2.49E-09 125NRG1_H2O2HiWT_V71E Chitikila_02 -8.55 2.80E-09 105MSN2_H2O2Higcn5D_taf1-ts2Durant06 8.5 3.10E-09 75HSF1_H2O2Hi rsc3-2 Angus-Hill_01 8.49 3.23E-09 123GCN4_YPD ubp10 Orlandi04 -8.48 3.25E-09 60SKN7_H2O2Hi esa1-414 Durant06 8.47 3.32E-09 94PHD1_YPD Hda1_del Bernstein02 8.44 3.55E-09 66GCN4_YPD esa1-414 Durant06 8.42 3.75E-09 69MSN2_H2O2Hiesa1-414 Durant06 8.41 3.87E-09 74GCN4_RAPA ZDS1 Hughes00 8.4 3.93E-09 159SKN7_YPD SSN6_haploid Hughes00 8.4 3.98E-09 66HAP4_YPD isw2_c.i._rpd3_c.i.Fazzio01 -8.38 4.15E-09 64HSF1_H2O2LoRSC8 Mnaimneh_04 8.32 4.69E-09 101CBF1_SM esa1-414 Durant06 8.31 4.84E-09 254SWI4_YPD VID21 Krogan04 8.28 5.16E-09 139RPN4_H2O2LoARD1 Hughes00 8.25 5.54E-09 98GCN4_SM ZDS1 Hughes00 8.24 5.67E-09 187ABF1_YPD gcn5D_taf1-ts2Durant06 8.24 5.70E-09 254RPN4_H2O2Lotaf1-ts2_GCN5Huisinga04 8.21 6.06E-09 92HAP1_YPD WT_F182V Chitikila_02 8.21 6.11E-09 131MSN2_H2O2HiDT_Null Chitikila_02 8.21 6.15E-09 75SWI4_YPD 0.1%_MMS Attikum04 -8.19 6.43E-09 122SWI4_YPD esa1-414_taf1-ts2Durant06 8.17 6.65E-09 142GCN4_SM IES6 Hughes00 -8.16 6.84E-09 189ABF1_YPD DT_V161E Chitikila_02 8.16 6.89E-09 243SKN7_YPD ARP4 Mnaimneh_04 8.15 6.92E-09 67GCN4_RAPA Dsin3 Keogh05 8.12 7.54E-09 133MSN2_H2O2Hitaf1-ts2_SPT3 Huisinga04 8.1 7.80E-09 76MBP1_YPD isw2_c.i._rpd3_c.i.Fazzio01 8.03 9.22E-09 123FKH2_YPD sin3 Fazzio01 8.01 9.76E-09 119GCN4_SM sir4 Orlandi04 -8 9.78E-09 153FKH2_H2O2Hi SIR2 Hughes00 -7.98 1.03E-08 106GCN4_YPD ume6 Fazzio01 7.98 1.04E-08 74YAP7_H2O2Lo 0.1%_MMS Attikum04 7.96 1.08E-08 131SWI4_YPD WT_V161E Chitikila_02 -7.95 1.10E-08 148YAP6_YPD spt3 Huisinga04 -7.95 1.10E-08 90ABF1_YPD spt3 Huisinga04 7.93 1.15E-08 252YAP6_H2O2Hi isw2_rpd3 Fazzio01 -7.91 1.23E-08 73MBP1_H2O2Hi isw2_sin3 Fazzio01 7.89 1.28E-08 126HSF1_H2O2LoWT_TAF1_GCN5Huisinga04 -7.88 1.30E-08 100SWI6_YPD SIN3 Hughes00 7.84 1.43E-08 151UME6_H2O2HiDrpd3 Keogh05 7.83 1.45E-08 93RPN4_H2O2Lo0.1%_MMS Attikum04 7.83 1.45E-08 87SKN7_H2O2LoWT_V161R_L Chitikila_02 -7.81 1.54E-08 179HAP4_YPD swr1 Meneghini03 7.79 1.59E-08 52MSN2_H2O2Hitaf1-ts2 Durant06 7.77 1.67E-08 78UME6_YPD ume6_del Bernstein_00_affydeletions7.75 1.74E-08 125GCN4_SM 0.1%_MMS Attikum04 7.75 1.75E-08 165SOK2_BUT14 Hda1_del Bernstein02 7.75 1.77E-08 71GCN4_YPD Dpho23 Keogh05 7.73 1.84E-08 73SKN7_YPD YNG2 Krogan04 7.72 1.89E-08 64HAP4_YPD TUP1_haploid Hughes00 7.71 1.94E-08 66RPN4_H2O2Loarp8_+_0.1%_MMS_vs._arp8Attikum04 7.69 2.02E-08 86

GCN4_RAPA IES6 Hughes00 -7.69 2.04E-08 160HAP4_YPD Dpho23 Keogh05 -7.67 2.12E-08 65GCN4_RAPA Drxt1 Keogh05 7.65 2.22E-08 160GCN4_YPD ISW1_ISW2 Hughes00 7.64 2.24E-08 75SWI6_YPD HDA1 Hughes00 -7.64 2.26E-08 152SKN7_H2O2Loelp3D_taf1-ts2Durant06 7.64 2.28E-08 144SUM1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -7.61 2.44E-08 59MBP1_H2O2Hi isw2_rpd3 Fazzio01 7.61 2.44E-08 126SKN7_H2O2Lotaf1-ts2_SPT3 Huisinga04 7.58 2.62E-08 172RPN4_H2O2Lotaf1-ts2_spt3_E240KHuisinga04 7.58 2.63E-08 93SOK2_BUT14 spt3 Huisinga04 -7.56 2.71E-08 71HAP4_YPD WT_V161R_L Chitikila_02 -7.55 2.79E-08 65NRG1_YPD Hda1_del Bernstein02 7.54 2.84E-08 72MSN2_H2O2Hihpa2D_taf1-ts2Durant06 7.54 2.85E-08 69SKN7_H2O2Lotaf1-ts2_gcn5 Huisinga04 7.53 2.93E-08 174SUM1_YPD Rpd3_del Bernstein02 -7.5 3.13E-08 56HAP4_YPD WT_N69R Chitikila_02 -7.49 3.23E-08 65SKN7_YPD esa1-414 Durant06 7.48 3.27E-08 64SKN7_H2O2LoDT_V161E Chitikila_02 -7.47 3.36E-08 172GCN4_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 7.45 3.51E-08 67HAP4_YPD WT_V161R_K Chitikila_02 -7.43 3.65E-08 63NRG1_H2O2HiWT_V161E Chitikila_02 -7.43 3.68E-08 113SWI4_YPD taf1-ts2_spt3 Huisinga04 -7.42 3.75E-08 151MSN4_H2O2Hiesa1-414 Durant06 7.4 3.95E-08 65GCN4_YPD SIR1 Hughes00 7.4 3.96E-08 75HSF1_H2O2LoWT_F182V Chitikila_02 7.39 4.06E-08 89SKN7_H2O2LoWT_N69S Chitikila_02 -7.34 4.50E-08 167SWI6_YPD WT_N69S Chitikila_02 -7.34 4.52E-08 139GCN4_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 7.3 4.95E-08 68YAP6_H2O2Hi isw2_c.i. Fazzio01 -7.29 5.12E-08 73SWI4_YPD WT_V161R_K Chitikila_02 -7.28 5.17E-08 147MBP1_H2O2Hi taf1-ts2_spt3 Huisinga04 -7.28 5.19E-08 124UME6_H2O2Hiisw2_sin3 Fazzio01 7.27 5.25E-08 98RPN4_H2O2Lotaf1-ts2_spt3 Huisinga04 7.27 5.36E-08 97UME6_H2O2Hiisw2_rpd3 Fazzio01 7.26 5.43E-08 98SKN7_H2O2Lohtz1_del Mizuguch04 7.24 5.68E-08 185GCN4_YPD esa1-414_taf1-ts2Durant06 7.22 5.94E-08 72SKN7_H2O2Lohat1D_taf1-ts2Durant06 7.21 6.07E-08 148SWI4_YPD WT_V71R Chitikila_02 -7.2 6.18E-08 145FKH2_H2O2Hi RPD3_haploid Hughes00 7.19 6.43E-08 106PUT3_H2O2Lo swr1_del Mizuguch04 7.18 6.52E-08 88HAP4_YPD hht2_K49141823GMartin04 7.16 6.84E-08 53NRG1_H2O2Hispt3_E240K Huisinga04 -7.14 7.08E-08 111HAP4_YPD ARP4 Mnaimneh_04 7.13 7.33E-08 67GCN4_RAPA sir4 Orlandi04 -7.1 7.81E-08 125HAP1_YPD isw2_c.i. Fazzio01 -7.1 7.85E-08 136HSF1_H2O2LoYNG2 Krogan04 7.1 7.93E-08 98HAP4_YPD htz1_sir2 Meneghini03 7.09 7.96E-08 63FKH2_YPD SIN3 Hughes00 7.09 8.11E-08 121SUT1_YPD Hda1_del Bernstein02 7.07 8.34E-08 69YAP6_H2O2Lo isw2_rpd3 Fazzio01 -7.06 8.66E-08 57SUM1_YPD Ddep1 Keogh05 -7.05 8.87E-08 49RPN4_H2O2Lohpa2D_taf1-ts2Durant06 7.04 9.00E-08 84

MSN4_H2O2Hiesa1-414_taf1-ts2Durant06 7.02 9.42E-08 64GCR2_SM esa1-414 Durant06 7.02 9.54E-08 50ABF1_YPD WT_V71E Chitikila_02 7 1.00E-07 231HSF1_H2O2Hi WT_F182V Chitikila_02 7 1.00E-07 112GCN4_RAPA SIR1 Hughes00 6.97 1.07E-07 160RPN4_H2O2Lospt10_del Xu05 6.97 1.07E-07 99HAP4_YPD rpd3 Fazzio01 -6.97 1.07E-07 63SWI6_YPD RPD3_haploid Hughes00 6.96 1.08E-07 152SKN7_H2O2Lotaf1-ts2 Durant06 6.95 1.12E-07 182RCS1_H2O2Lospt10 Eriksson05 -6.91 1.23E-07 259GCN4_RAPA esa1-414_taf1-ts2Durant06 6.9 1.25E-07 153ABF1_YPD Set1_del Bernstein02 -6.89 1.26E-07 264ABF1_YPD hos2_del Bernstein_00_affydeletions6.88 1.30E-07 253FKH2_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 6.88 1.30E-07 104HAP1_YPD ARP4 Mnaimneh_04 6.87 1.34E-07 141YAP7_H2O2Lo HST3 Hughes00 6.86 1.35E-07 149HSF1_H2O2Hi WT_V161E Chitikila_02 -6.84 1.44E-07 118MSN2_H2O2HiBUR6 Geisberg_01 6.83 1.45E-07 71HAP1_YPD WT_V161R_L Chitikila_02 -6.83 1.45E-07 140HAP4_YPD WT_V161E Chitikila_02 -6.83 1.46E-07 64HSF1_H2O2Losas3D_taf1-ts2Durant06 6.83 1.47E-07 89SWI6_YPD taf1-ts2_spt3 Huisinga04 -6.82 1.50E-07 149SKN7_YPD YNG2 Mnaimneh_04 6.79 1.59E-07 67ABF1_YPD DT_N69S Chitikila_02 6.79 1.62E-07 245MBP1_YPD taf1-ts2_gcn5 Huisinga04 -6.79 1.62E-07 123MSN2_H2O2HiWT_F182V Chitikila_02 6.78 1.63E-07 65MBP1_YPD isw2_sin3 Fazzio01 6.78 1.63E-07 123UME6_H2O2HiEPL1 Mnaimneh_04 6.78 1.64E-07 102SKN7_H2O2HiWT_V161E Chitikila_02 -6.75 1.76E-07 85STE12_BUT90 ARP4 Mnaimneh_04 6.75 1.76E-07 78STE12_Alpha Rpd3_del Bernstein02 -6.73 1.84E-07 111SWI4_YPD EPL1 Mnaimneh_04 6.7 1.95E-07 156UME6_YPD isw2_rpd3 Fazzio01 6.7 1.99E-07 125STE12_BUT14 htz1 Meneghini03 6.69 2.00E-07 125GCN4_SM Drxt2 Keogh05 6.69 2.01E-07 180SWI4_YPD DT_N69S Chitikila_02 -6.69 2.02E-07 145HSF1_H2O2Loesa1-414_taf1-ts2Durant06 6.69 2.03E-07 88SOK2_BUT14 hda1_del Bernstein_00_affydeletions6.67 2.13E-07 64NRG1_H2O2HiSet1_del Bernstein02 6.65 2.19E-07 124SUM1_YPD rpd3 Fazzio01 -6.64 2.25E-07 59RPN4_H2O2LoRAD6_haploid Hughes00 6.64 2.27E-07 99ABF1_YPD isw2_c.i. Fazzio01 6.61 2.42E-07 263MSN4_H2O2Hisas3D_taf1-ts2Durant06 6.6 2.50E-07 63HSF1_H2O2LoWT_TAF1_SPT3Huisinga04 -6.59 2.54E-07 99ABF1_YPD taf1-ts2_spt3 Huisinga04 6.59 2.55E-07 255AFT2_H2O2Lo swi1_rich_medium_experimentSudarsanam00 6.56 2.70E-07 98HAP1_YPD SSD1-V Kaeberlein04 6.56 2.70E-07 140YAP6_YPD isw2_c.i._rpd3_c.i.Fazzio01 -6.56 2.75E-07 87SKN7_H2O2Lohpa2D_taf1-ts2Durant06 6.55 2.77E-07 139MBP1_H2O2Loisw2_c.i._rpd3_c.i.Fazzio01 6.55 2.78E-07 54SWI4_YPD DT_V161E Chitikila_02 -6.55 2.79E-07 150HSF1_H2O2Hi htz1 Meneghini03 6.54 2.83E-07 122SUM1_YPD RPD3_haploid Hughes00 -6.54 2.86E-07 58

RPN4_H2O2Lotaf1-ts2_gcn5 Huisinga04 6.54 2.88E-07 93SWI6_YPD VID21 Krogan04 6.53 2.90E-07 142HSF1_H2O2Hi esa1-414_taf1-ts2Durant06 6.52 2.98E-07 112SWI4_YPD WT_V71E Chitikila_02 -6.51 3.05E-07 135FKH2_H2O2Hi 0.1%_MMS Attikum04 -6.5 3.11E-07 84RIM101_H2O2LoHda1_del Bernstein02 6.49 3.20E-07 53GCN4_RAPA ISW1 Hughes00 -6.48 3.27E-07 160UME6_YPD EPL1 Mnaimneh_04 6.47 3.37E-07 131STE12_BUT14 htz1_hmr Meneghini03 6.46 3.42E-07 127HAP1_YPD DT_V161E Chitikila_02 -6.45 3.49E-07 136GCN4_SM Rpd3_del Bernstein02 6.45 3.54E-07 189NRG1_H2O2HiYNG2 Mnaimneh_04 6.44 3.57E-07 126MSN2_H2O2Hihtz1_sir2 Meneghini03 6.44 3.62E-07 78SWI6_YPD WT_N69R Chitikila_02 -6.43 3.67E-07 140GCN4_SM sir2 Meneghini03 6.43 3.69E-07 183HAP4_YPD EPL1 Mnaimneh_04 6.42 3.76E-07 67GCN4_SM Dume1 Keogh05 6.42 3.77E-07 177SWI6_YPD sin3 Fazzio01 6.41 3.84E-07 148MBP1_YPD gcn5 Huisinga04 -6.41 3.84E-07 125UME6_H2O2Hiisw2_ume6 Fazzio01 6.4 3.93E-07 98STE12_YPD htz1 Meneghini03 6.38 4.11E-07 52YAP6_YPD hda1_del Bernstein_00_affydeletions6.38 4.12E-07 79SKN7_H2O2Hi esa1-414_taf1-ts2Durant06 6.36 4.28E-07 92YAP6_H2O2Hi UBP8 Ingvarsdottir05 6.36 4.35E-07 69MSN2_H2O2HiRpd3_del Bernstein02 6.35 4.37E-07 77YAP6_H2O2Lo rpd3 Fazzio01 -6.35 4.44E-07 57MBP1_H2O2Hi rpd3 Fazzio01 6.33 4.66E-07 126FKH2_H2O2Hi Ddep1 Keogh05 6.32 4.68E-07 100RIM101_H2O2Loisw2_c.i. Fazzio01 -6.32 4.78E-07 52MSN4_H2O2HiBUR6 Geisberg_01 6.3 4.90E-07 65MSN2_H2O2HiWT_V71R Chitikila_02 -6.3 4.94E-07 74YAP6_H2O2Hi sir2 Meneghini03 6.3 4.98E-07 78HAP1_YPD VID21 Krogan04 6.29 5.07E-07 134RCS1_H2O2Hi swr1_del Mizuguch04 6.29 5.09E-07 52RPN4_H2O2LoDT_V161R_L Chitikila_02 -6.29 5.09E-07 97MBP1_H2O2Hi sin3 Fazzio01 6.28 5.13E-07 126YAP6_YPD isw2_sin3 Fazzio01 -6.28 5.16E-07 88CIN5_H2O2Hi SSN6_haploid Hughes00 6.28 5.19E-07 78HAP1_YPD WT_V161R_K Chitikila_02 -6.28 5.20E-07 135HSF1_H2O2LoVID21 Krogan04 6.27 5.26E-07 91GCN4_SM SPT3 Ingvarsdottir05 6.27 5.32E-07 170HSF1_H2O2Hi RSC8 Mnaimneh_04 6.25 5.52E-07 124PHD1_BUT90 spt3 Huisinga04 -6.25 5.57E-07 102MSN2_H2O2HiWT_V161R_K Chitikila_02 -6.25 5.60E-07 76GCN4_SM hpa2D_taf1-ts2Durant06 6.24 5.71E-07 153FKH2_YPD RPD3_haploid Hughes00 6.24 5.71E-07 120UME6_YPD Dsds3 Keogh05 6.23 5.80E-07 117SKN7_H2O2HiVID21 Krogan04 6.22 5.96E-07 85MSN4_H2O2Hitaf1-ts2_gcn5 Huisinga04 6.22 6.02E-07 65HAP4_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -6.21 6.03E-07 48NRG1_YPD spt3 Huisinga04 -6.2 6.29E-07 71MBP1_YPD esa1-414 Durant06 6.19 6.40E-07 118NRG1_YPD isw2_rpd3 Fazzio01 -6.18 6.50E-07 70

GCN4_SM RAD6_haploid Hughes00 6.17 6.65E-07 188UME6_YPD Ddep1 Keogh05 6.16 6.84E-07 112PHD1_YPD isw2_rpd3_vs._rpd3Fazzio01 -6.15 6.93E-07 66XBP1_H2O2Lo SSN6_haploid Hughes00 6.15 6.99E-07 66STE12_BUT14 arp8 Attikum04 -6.14 7.17E-07 106SUT1_YPD sir2 Meneghini03 6.14 7.22E-07 65CIN5_H2O2Lo isw2_sin3 Fazzio01 -6.13 7.34E-07 125GCN4_RAPA taf1-ts2_SPT3 Huisinga04 6.13 7.40E-07 155HAP4_YPD spt3 Huisinga04 6.11 7.75E-07 66CIN5_YPD DM_vs._YPH250Rosaleny05 6.1 7.84E-07 134MSN4_H2O2Hitaf1-ts2 Durant06 6.1 7.86E-07 69RIM101_H2O2LoSet1_del Bernstein02 6.1 7.92E-07 52REB1_YPD spt3 Huisinga04 6.1 7.93E-07 133HAP1_YPD sas3D_taf1-ts2Durant06 6.09 8.00E-07 134DAL81_RAPA taf1-ts2 Durant06 6.08 8.14E-07 94MSN2_H2O2Hihat1D_taf1-ts2Durant06 6.08 8.18E-07 70SUT1_YPD spt3 Huisinga04 -6.06 8.57E-07 69RIM101_H2O2Lospt3 Huisinga04 -6.05 8.81E-07 53MSN2_H2O2Hielp3D_taf1-ts2Durant06 6.04 9.07E-07 68SWI4_YPD taf1-ts2_spt3_E240KHuisinga04 -6.04 9.10E-07 136GCN4_SM Dsap30 Keogh05 6.02 9.53E-07 179MSN2_H2O2HiWT_V161E Chitikila_02 -6.02 9.54E-07 76CIN5_H2O2Lo isw2_c.i. Fazzio01 -6.01 9.61E-07 125YAP7_H2O2Lo TUP1_haploid Hughes00 6.01 9.74E-07 149SKN7_H2O2LoRSC8 Mnaimneh_04 6 9.79E-07 186SWI6_YPD WT_V161E Chitikila_02 -6 9.80E-07 145HAP1_YPD WT_V161E Chitikila_02 -6 9.92E-07 134SUM1_YPD Drxt2 Keogh05 -5.99 1.00E-06 52GCN4_SM sas3D_taf1-ts2Durant06 5.98 1.03E-06 173GCN4_YPD SWD2 Mnaimneh_04 5.98 1.03E-06 75SKN7_YPD EPL1 Mnaimneh_04 5.97 1.05E-06 67SWI4_YPD WT_V161R_L Chitikila_02 -5.97 1.06E-06 150MSN2_H2O2Hiino80_+_0.1%_MMS_vs._ino80Attikum04 5.97 1.06E-06 64HSF1_H2O2Logcn5D_taf1-ts2Durant06 5.97 1.06E-06 93RIM101_H2O2Lorpd3_c.i. Fazzio01 -5.97 1.06E-06 52STE12_BUT14 htz1_del Mizuguch04 5.97 1.06E-06 127SWI6_YPD isw2_c.i._rpd3_c.i.Fazzio01 5.95 1.10E-06 148HAP4_YPD DT_V161E Chitikila_02 -5.95 1.10E-06 65STE12_YPD RAD6_haploid Hughes00 -5.95 1.12E-06 50UME6_H2O2HiSIN3 Hughes00 5.94 1.14E-06 101HSF1_H2O2Lohat1_vs.YPH250Rosaleny05 5.93 1.17E-06 98FKH2_YPD esa1-414 Durant06 5.93 1.17E-06 109GCN4_RAPA Drpd3 Keogh05 5.92 1.18E-06 148GCN4_YPD Drxt1 Keogh05 5.92 1.19E-06 75HSF1_H2O2Hi EPL1 Mnaimneh_04 5.91 1.21E-06 124RPN4_H2O2Loelp3D_taf1-ts2Durant06 5.91 1.21E-06 82NRG1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -5.91 1.21E-06 70MBP1_YPD taf1-ts2_spt3_E240KHuisinga04 -5.91 1.22E-06 114HSF1_H2O2Hi TAF2 Mnaimneh_04 5.91 1.23E-06 123STE12_YPD sap30_del Bernstein_00_affydeletions-5.89 1.28E-06 49RCS1_H2O2LoRAD6_haploid Hughes00 5.88 1.29E-06 254SKN7_H2O2Losir4 Orlandi04 -5.88 1.30E-06 117NRG1_YPD ino80_del Mizuguch04 5.88 1.30E-06 72

GCN4_SM taf1-ts2 Durant06 5.88 1.31E-06 187MBP1_H2O2Loisw2_sin3 Fazzio01 5.87 1.32E-06 54ABF1_YPD EAF7 Krogan04 -5.87 1.34E-06 245UME6_H2O2HiRPD3_haploid Hughes00 5.87 1.34E-06 100MSN2_H2O2Hiarp8_+_0.1%_MMS_vs._arp8Attikum04 5.86 1.35E-06 65SKN7_H2O2HiARP4 Mnaimneh_04 5.86 1.35E-06 98HSF1_H2O2LoDT_WT Chitikila_02 5.86 1.36E-06 97SWI6_YPD taf1-ts2_spt3_E240KHuisinga04 -5.86 1.37E-06 139HSF1_H2O2LoARP4 Mnaimneh_04 5.86 1.38E-06 101GCN4_SM taf1-ts2_SPT3 Huisinga04 5.85 1.39E-06 181DAL81_RAPA Drpd3 Keogh05 5.82 1.50E-06 85YAP6_H2O2Lo isw2_sin3 Fazzio01 -5.82 1.50E-06 57SKN7_H2O2LoDT_Null Chitikila_02 5.81 1.53E-06 178YAP1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 5.8 1.55E-06 62HAP1_YPD hht2_K27G Martin04 5.8 1.55E-06 118UME6_YPD sin3 Fazzio01 5.8 1.57E-06 125XBP1_H2O2Lo rpd3_c.i. Fazzio01 -5.8 1.57E-06 65SWI6_YPD DT_N69S Chitikila_02 -5.79 1.61E-06 144HSF1_H2O2LoEPL1 Mnaimneh_04 5.79 1.61E-06 101HSF1_H2O2Lorsc30_null Angus-Hill_01 -5.79 1.61E-06 98YAP6_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 -5.79 1.62E-06 72GCN4_SM ARD1 Hughes00 5.78 1.63E-06 186SKN7_H2O2Hi htz1_del Mizuguch04 5.78 1.63E-06 97STE12_YPD htz1_del Mizuguch04 5.78 1.65E-06 54DAL81_RAPA hpa2D_taf1-ts2Durant06 5.78 1.65E-06 75HSF1_H2O2Hi htz1_hmr Meneghini03 5.78 1.65E-06 122GCR2_SM WT_V161R_L Chitikila_02 -5.77 1.67E-06 52HSF1_H2O2Lohpa2D_taf1-ts2Durant06 5.76 1.70E-06 85MBP1_H2O2HiWT_WT Chitikila_02 -5.76 1.72E-06 126HAP1_YPD isw2_sin3_vs._sin3Fazzio01 -5.75 1.76E-06 136HSF1_H2O2LoTAF2 Mnaimneh_04 5.75 1.77E-06 100ABF1_YPD WT_V161E Chitikila_02 5.74 1.79E-06 240FKH2_H2O2Hi Dpho23 Keogh05 5.74 1.80E-06 104DAL81_RAPA esa1-414_taf1-ts2Durant06 5.73 1.85E-06 87PUT3_H2O2Lo SSN6_haploid Hughes00 5.73 1.86E-06 88GCN4_SM elp3D_taf1-ts2Durant06 5.72 1.88E-06 155MBP1_YPD WT_N69R Chitikila_02 -5.72 1.89E-06 117STE12_YPD rpd3_c.i. Fazzio01 -5.71 1.92E-06 54HSF1_H2O2Lohtz1 Meneghini03 5.71 1.94E-06 100HSF1_H2O2LoWT_V161E Chitikila_02 -5.71 1.94E-06 96SOK2_BUT14 spt3_E240K Huisinga04 -5.71 1.94E-06 65DAL81_RAPA sas3D_taf1-ts2Durant06 5.7 1.96E-06 84CIN5_H2O2Lo Set1_del Bernstein02 5.69 2.01E-06 127NRG1_YPD rpd3_c.i. Fazzio01 -5.69 2.03E-06 70GCN4_SM _SWC2_(VPS72)Krogan04 5.67 2.09E-06 174NRG1_YPD isw2_c.i. Fazzio01 -5.67 2.09E-06 70STE12_YPD htz1_hmr Meneghini03 5.67 2.10E-06 52HSF1_H2O2Lorsc3-2 Angus-Hill_01 5.67 2.10E-06 98STE12_BUT14 YAF9 Krogan04 5.67 2.13E-06 125NDD1_YPD esa1-414 Durant06 5.67 2.13E-06 78YAP6_H2O2Lo isw2_c.i._rpd3_c.i.Fazzio01 -5.66 2.14E-06 56HAP4_YPD rpd3_H3dN_v_H3dNSabet04 -5.66 2.14E-06 62SKN7_H2O2Lorsc30_null Angus-Hill_01 -5.66 2.17E-06 184

SWI4_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -5.66 2.18E-06 119GCN4_SM HAT2 Hughes00 -5.65 2.19E-06 189GCR2_SM esa1-414_taf1-ts2Durant06 5.65 2.19E-06 50HSF1_H2O2Hi YNG2 Krogan04 5.65 2.21E-06 121STE12_Alpha RAD6_haploid Hughes00 -5.65 2.22E-06 112FKH2_H2O2Hi isw2_sin3 Fazzio01 5.64 2.27E-06 104STE12_BUT14 ARP4 Mnaimneh_04 5.64 2.28E-06 128RCS1_H2O2Hi ISW1 Hughes00 -5.63 2.31E-06 51HAP4_YPD rpd3_H4KQ_v_H4KQSabet04 -5.63 2.34E-06 62NRG1_H2O2Hiesa1-414_taf1-ts2Durant06 5.62 2.35E-06 111SKN7_YPD RSC8 Mnaimneh_04 5.62 2.36E-06 67SKN7_H2O2Hi EPL1 Mnaimneh_04 5.62 2.37E-06 98FKH2_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 -5.61 2.40E-06 84STE12_Alpha htz1_del Mizuguch04 5.6 2.47E-06 115NRG1_YPD Rpd3_del Bernstein02 -5.6 2.51E-06 71SUM1_YPD isw2_sin3 Fazzio01 -5.59 2.52E-06 59SWI4_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -5.59 2.55E-06 121HAP1_YPD isw2 Fazzio01 -5.58 2.60E-06 136FKH2_H2O2Hi sin3 Fazzio01 5.58 2.61E-06 104RPN4_H2O2Lotaf1-ts2 Durant06 5.58 2.62E-06 96RPN4_H2O2Losas3D_taf1-ts2Durant06 5.58 2.62E-06 91SOK2_BUT14 ISW1 Hughes00 5.57 2.66E-06 72MBP1_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 -5.56 2.75E-06 115YAP7_H2O2Lo HDA1 Hughes00 5.56 2.75E-06 150HSF1_H2O2Hi rsc30_null Angus-Hill_01 -5.55 2.76E-06 123GCR2_SM spt10 Eriksson05 -5.55 2.77E-06 54SKN7_H2O2Hi TUP1_haploid Hughes00 5.55 2.78E-06 97PUT3_H2O2Lo ISW1 Hughes00 -5.54 2.83E-06 87CIN5_YPD isw2_c.i. Fazzio01 -5.54 2.86E-06 148SWI6_YPD DT_V161E Chitikila_02 -5.54 2.88E-06 145GCN4_SM ume6_del Bernstein_00_affydeletions5.53 2.91E-06 184NRG1_YPD RPD3_haploid Hughes00 -5.52 2.96E-06 72FKH2_H2O2Hi gcn5 Huisinga04 -5.52 2.99E-06 103RCS1_H2O2Hi SSN6_haploid Hughes00 5.52 2.99E-06 52MBP1_H2O2Hi taf1-ts2_gcn5 Huisinga04 -5.51 3.05E-06 123HAP1_YPD esa1-414_taf1-ts2Durant06 5.51 3.08E-06 132STE12_Alpha rpd3_del Sabet04 -5.5 3.11E-06 109CBF1_SM sir2 Meneghini03 5.49 3.23E-06 271MBP1_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 -5.48 3.24E-06 117GCN4_RAPA ARD1 Hughes00 5.48 3.25E-06 158ABF1_YPD DT_V71E Chitikila_02 5.48 3.28E-06 261GCN4_YPD ISW1 Hughes00 -5.48 3.28E-06 75UME6_YPD Rpd3_del Bernstein02 5.48 3.31E-06 129UME6_H2O2Hirpd3 Fazzio01 5.46 3.43E-06 98STE12_BUT90 htz1_hmr Meneghini03 5.46 3.44E-06 76SWI6_YPD YNG2 Krogan04 5.45 3.53E-06 151UME6_H2O2HiDsin3 Keogh05 5.44 3.55E-06 82CIN5_H2O2Lo Hda1_del Bernstein02 5.44 3.57E-06 127YAP7_H2O2Hi IOC4 Hughes00 -5.43 3.67E-06 141ASH1_BUT14 esa1-414_taf1-ts2Durant06 5.43 3.69E-06 48NRG1_YPD sin3 Fazzio01 -5.43 3.69E-06 70FKH2_YPD isw2_c.i._rpd3_c.i.Fazzio01 5.43 3.70E-06 119GCR2_SM WT_N69R Chitikila_02 -5.43 3.71E-06 50

SWI6_YPD SIR2 Hughes00 -5.41 3.82E-06 153ASH1_BUT14 ARP4 Mnaimneh_04 5.41 3.85E-06 50HAP4_YPD sin3 Fazzio01 -5.4 3.98E-06 64YAP7_H2O2Hi HST3 Hughes00 5.39 4.00E-06 139FKH2_YPD Rpd3_del Bernstein02 5.38 4.12E-06 120YAP6_YPD sin3 Fazzio01 -5.38 4.16E-06 88GCN4_SM WT_V161E Chitikila_02 -5.37 4.26E-06 177MSN2_H2O2HiWT_V71E Chitikila_02 -5.37 4.26E-06 76GCN4_YPD IES6 Hughes00 -5.36 4.27E-06 75RCS1_H2O2Lospt3_E240K Huisinga04 5.36 4.32E-06 235CIN5_H2O2Lo isw2_c.i._rpd3_c.i.Fazzio01 -5.36 4.33E-06 124NRG1_YPD isw2_sin3 Fazzio01 -5.36 4.33E-06 70ABF1_YPD swi1_rich_medium_experimentSudarsanam00 -5.36 4.34E-06 267HSF1_H2O2Hi ARP4 Mnaimneh_04 5.36 4.36E-06 124SWI6_YPD WT_V71R Chitikila_02 -5.35 4.37E-06 141CIN5_H2O2Lo sin3 Fazzio01 -5.35 4.37E-06 125GLN3_RAPA SIR2 Hughes00 5.35 4.41E-06 68GCN4_SM WT_N69R Chitikila_02 -5.34 4.48E-06 178NRG1_YPD Dpho23 Keogh05 -5.34 4.48E-06 71GCN4_YPD PCH1 Hughes00 5.34 4.57E-06 73SKN7_H2O2HiWT_V71E Chitikila_02 -5.33 4.60E-06 80PHD1_BUT90 esa1-414_taf1-ts2Durant06 5.33 4.64E-06 94GCN4_RAPA SPT3 Ingvarsdottir05 5.32 4.76E-06 143SWI4_YPD spt3 Huisinga04 -5.32 4.78E-06 151GCN4_RAPA RAD6_haploid Hughes00 5.31 4.84E-06 159CIN5_YPD IES6 Hughes00 -5.31 4.85E-06 149DAL81_RAPA DM_vs._YPH250Rosaleny05 5.31 4.86E-06 89HSF1_H2O2Lohos2_del Bernstein_00_affydeletions5.31 4.89E-06 97RPN4_H2O2Lospt3_E240K Huisinga04 5.3 4.97E-06 89ABF1_YPD ARD1 Hughes00 5.29 5.04E-06 264CIN5_YPD esa1-414_taf1-ts2Durant06 5.29 5.04E-06 130AFT2_H2O2Lo sir2 Meneghini03 5.29 5.04E-06 95SWI4_YPD DT_WT Chitikila_02 -5.29 5.08E-06 150MBP1_YPD WT_N69S Chitikila_02 -5.28 5.14E-06 118SWI6_YPD EPL1 Mnaimneh_04 5.28 5.15E-06 153HSF1_H2O2Lohtz1_hmr Meneghini03 5.28 5.16E-06 100RIM101_H2O2Loisw2_sin3 Fazzio01 -5.28 5.17E-06 52HSF1_H2O2Lotaf1-ts2_spt3 Huisinga04 5.27 5.34E-06 97YAP1_YPD HIR2 Hughes00 5.27 5.35E-06 72HAP1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -5.27 5.35E-06 114STE12_Alpha sap30_del Bernstein_00_affydeletions-5.27 5.37E-06 105UME6_YPD ARP4 Mnaimneh_04 5.26 5.39E-06 131SUM1_YPD sin3 Fazzio01 -5.26 5.45E-06 59MBP1_YPD DT_N69S Chitikila_02 -5.25 5.58E-06 120YAP6_H2O2Lo SIN3 Hughes00 -5.23 5.78E-06 58HAP4_YPD elp3D Durant06 -5.23 5.78E-06 57MSN4_H2O2Hihpa2D_taf1-ts2Durant06 5.23 5.80E-06 59CIN5_H2O2Lo rpd3_c.i. Fazzio01 -5.22 5.97E-06 125RLM1_YPD VID21 Krogan04 5.22 5.98E-06 50AFT2_H2O2Lo SWD2 Mnaimneh_04 5.22 6.00E-06 98HSF1_H2O2Lotaf1-ts2_gcn5 Huisinga04 5.21 6.07E-06 94SKN7_H2O2Lohht2_K27G Martin04 5.21 6.14E-06 143UME6_YPD SIN3 Hughes00 5.2 6.24E-06 128

ASH1_BUT14 YAF9 Krogan04 5.2 6.27E-06 45MSN4_H2O2HiWT_F182V Chitikila_02 5.2 6.28E-06 62UME6_H2O2HiDdep1 Keogh05 5.19 6.38E-06 87GLN3_RAPA WT_V161E Chitikila_02 -5.18 6.53E-06 65GCN4_RAPA elp3D_taf1-ts2Durant06 5.17 6.61E-06 130HSF1_H2O2LoYNG2 Mnaimneh_04 5.17 6.66E-06 101YAP6_H2O2Hi isw2_sin3 Fazzio01 -5.17 6.67E-06 73MSN4_H2O2Higcn5D Durant06 5.16 6.78E-06 60HSF1_H2O2Hi rpd3_H3dN_v_H3dNSabet04 5.16 6.80E-06 121YAP7_H2O2Hi H3_1-28 Sabet04 5.15 7.06E-06 138MSN4_H2O2HiWT_V71E Chitikila_02 -5.14 7.14E-06 66SOK2_BUT14 H4KQ Sabet04 5.14 7.24E-06 65AFT2_H2O2Lo SSN6_haploid Hughes00 5.13 7.32E-06 96SWI5_YPD hat1_vs.YPH250Rosaleny05 5.13 7.36E-06 93GCN4_SM taf1-ts2_GCN5Huisinga04 5.11 7.59E-06 176MSN2_H2O2Higcn5D Durant06 5.11 7.68E-06 68GCN4_SM HTZ1 Krogan04 5.11 7.72E-06 168YAP7_H2O2Hi HIR2 Hughes00 5.1 7.88E-06 140HAP4_YPD DT_N69R Chitikila_02 -5.1 7.91E-06 64SWI4_YPD YNG2 Mnaimneh_04 5.09 8.01E-06 156RCS1_H2O2Hi ISW1_ISW2 Hughes00 -5.09 8.04E-06 52PHD1_BUT90 ARP4 Mnaimneh_04 5.09 8.10E-06 106MBP1_YPD taf1-ts2_spt3 Huisinga04 -5.08 8.13E-06 123NRG1_YPD MOT1-14 Dasgupta02 5.08 8.27E-06 72NRG1_H2O2Hispt3 Huisinga04 -5.08 8.29E-06 120STE12_Alpha htz1 Meneghini03 5.08 8.31E-06 114GCN4_SM isw2_sin3_vs._sin3Fazzio01 -5.07 8.37E-06 183FKH2_H2O2Hi DT_Null Chitikila_02 5.07 8.38E-06 95HSF1_H2O2Loubp10 Orlandi04 5.07 8.50E-06 74GCN4_RAPA _SWC2_(VPS72)Krogan04 5.06 8.60E-06 147RIM101_H2O2Loisw2_rpd3 Fazzio01 -5.06 8.66E-06 52GCN4_RAPA gcn5_KQL Huisinga04 -5.05 8.81E-06 142DAL81_RAPA ubp10sir4 Orlandi04 -5.04 8.97E-06 70SUM1_YPD Set1_del Bernstein02 5.04 9.02E-06 57PHD1_YPD Set1_del Bernstein02 5.04 9.07E-06 66HSF1_H2O2Hi SSN6_haploid Hughes00 5.02 9.41E-06 122HAP1_YPD EPL1 Mnaimneh_04 5.02 9.43E-06 141PHD1_YPD spt3 Huisinga04 -5.01 9.56E-06 67MSN2_H2O2HiH4_2-26 Sabet04 5.01 9.61E-06 74MSN2_H2O2HiH4KQ Sabet04 5 9.80E-06 74FKH1_YPD HDA1 Hughes00 -5 9.85E-06 141NRG1_H2O2HiVID21 Krogan04 5 9.86E-06 109MSN4_H2O2HiDT_Null Chitikila_02 5 9.96E-06 70NRG1_YPD rpd3 Fazzio01 -4.99 1.01E-05 70FKH2_H2O2Hi Drpd3 Keogh05 4.99 1.02E-05 101CIN5_H2O2Lo hat1D Durant06 -4.98 1.04E-05 88PUT3_H2O2Lo taf1-ts2_gcn5_KQLHuisinga04 4.98 1.04E-05 79XBP1_H2O2Lo MOT1-14 Dasgupta02 4.98 1.04E-05 66NRG1_H2O2HiWT Durant06 -4.97 1.05E-05 118SOK2_BUT14 Set1_del Bernstein02 4.97 1.05E-05 71SUT1_YPD isw2_c.i. Fazzio01 -4.97 1.06E-05 69YAP6_YPD isw2_c.i. Fazzio01 -4.97 1.07E-05 87GCN4_SM WT_Null_L Chitikila_02 4.97 1.07E-05 177

AFT2_H2O2Lo RPD3_haploid Hughes00 4.97 1.07E-05 98HAP4_YPD Drxt1 Keogh05 -4.97 1.07E-05 67MBP1_H2O2HiSIN3 Hughes00 4.95 1.10E-05 132ABF1_YPD spt10 Eriksson05 -4.95 1.11E-05 265NRG1_H2O2HiWT_N69R Chitikila_02 -4.95 1.12E-05 114SKN7_H2O2LoTAF2 Mnaimneh_04 4.94 1.13E-05 186UME6_YPD rpd3 Fazzio01 4.94 1.14E-05 125HSF1_H2O2Hi HTZ1 Krogan04 4.93 1.15E-05 113XBP1_H2O2Lo Hda1_del Bernstein02 4.93 1.15E-05 68HSF1_H2O2Hi sas3D_taf1-ts2Durant06 4.93 1.16E-05 110YAP6_H2O2Hi TUP1_haploid Hughes00 4.93 1.16E-05 78YAP6_H2O2Hi Set1_del Bernstein02 4.93 1.17E-05 79GCR2_SM taf1-ts2 Durant06 4.92 1.18E-05 53FKH2_H2O2Hi SIN3 Hughes00 4.92 1.19E-05 106MSN4_H2O2HiHST3 Hughes00 4.92 1.19E-05 69NDD1_YPD ARP4 Mnaimneh_04 4.92 1.20E-05 85MBP1_H2O2HiWT_N69S Chitikila_02 -4.91 1.21E-05 123NRG1_H2O2Hisas3D_taf1-ts2Durant06 4.91 1.21E-05 111GCR2_SM isw2_sin3_vs._sin3Fazzio01 -4.91 1.22E-05 52CIN5_YPD isw2_c.i._rpd3_c.i.Fazzio01 -4.9 1.24E-05 147SWI6_YPD isw2_sin3 Fazzio01 4.9 1.25E-05 148PHD1_BUT90 DT_WT Chitikila_02 -4.89 1.27E-05 99MSN4_H2O2HiWT_V71R Chitikila_02 -4.88 1.30E-05 64UME6_YPD isw2_sin3 Fazzio01 4.87 1.32E-05 125GCN4_SM rpd3_H3dN_v_H3dNSabet04 4.87 1.34E-05 185HSF1_H2O2Lohat1D Durant06 4.86 1.38E-05 77HAP4_YPD WT_V71E Chitikila_02 -4.85 1.39E-05 61GCN4_SM snf2_rich_medium_experimentSudarsanam00 4.85 1.40E-05 187PHD1_BUT90 rpd3_H4KQ_v_H4KQSabet04 -4.85 1.41E-05 96PHD1_BUT90 isw2_rpd3_vs._rpd3Fazzio01 -4.83 1.45E-05 103GCN4_SM htz1_sir2 Meneghini03 4.82 1.50E-05 183GCN4_SM sin3 Fazzio01 4.82 1.51E-05 183HSF1_H2O2Hi YNG2 Mnaimneh_04 4.81 1.53E-05 124MBP1_H2O2Lohat2_vs._hat1Rosaleny05 -4.8 1.55E-05 55GCN4_YPD elp3D_taf1-ts2Durant06 4.8 1.57E-05 62SUT1_YPD isw2_rpd3 Fazzio01 -4.8 1.58E-05 69SKN7_H2O2LoBUR6 Geisberg_01 4.79 1.59E-05 175HAP4_YPD VID21 Krogan04 4.79 1.59E-05 56NRG1_YPD hda1_del Bernstein_00_affydeletions4.79 1.59E-05 56DAL82_RAPA Rpd3_del Bernstein02 -4.79 1.60E-05 55SKN7_H2O2HiWT_V71R Chitikila_02 -4.78 1.65E-05 84SWI4_YPD HDA1 Hughes00 -4.76 1.71E-05 156GCN4_RAPA WT_Null_L Chitikila_02 4.76 1.72E-05 151HAP4_YPD WT_F182V Chitikila_02 4.76 1.72E-05 59CIN5_YPD Hda1_del Bernstein02 4.76 1.73E-05 148GCN4_RAPA hpa2D_taf1-ts2Durant06 4.76 1.73E-05 129RIM101_H2O2Loswr1 Meneghini03 -4.76 1.73E-05 42STE12_BUT90 htz1_del Mizuguch04 4.76 1.73E-05 77UME6_YPD Dsin3 Keogh05 4.75 1.74E-05 110SWI4_YPD elp3D_taf1-ts2Durant06 4.75 1.76E-05 130GCN4_YPD ZDS1 Hughes00 4.75 1.76E-05 74GCR2_SM WT_WT Chitikila_02 -4.75 1.77E-05 53MBP1_H2O2Hi isw2_c.i. Fazzio01 4.74 1.78E-05 126

MSN4_H2O2Hielp3D_taf1-ts2Durant06 4.74 1.78E-05 60SUM1_YPD H4_2-26 Sabet04 4.74 1.79E-05 54YAP6_YPD RPD3_haploid Hughes00 -4.74 1.79E-05 91SWI4_YPD UBP8 Hughes00 4.74 1.80E-05 155GCN4_RAPA rpd3_H3dN_v_H3dNSabet04 4.73 1.82E-05 157SKN7_H2O2Hi taf1-ts2_GCN5Huisinga04 4.73 1.82E-05 90AFT2_H2O2Lo ISW2 Hughes00 -4.73 1.82E-05 98YAP6_H2O2Hi Hda1_del Bernstein02 4.73 1.83E-05 79REB1_YPD spt10 Eriksson05 -4.73 1.86E-05 145DIG1_BUT14 ARP4 Mnaimneh_04 4.72 1.87E-05 63GCR2_SM gcn5D_taf1-ts2Durant06 4.72 1.89E-05 50STE12_Alpha taf1-ts2_GCN5Huisinga04 4.72 1.90E-05 107GCN4_YPD SPT3 Ingvarsdottir05 4.72 1.90E-05 65FKH2_H2O2Hi isw2_c.i. Fazzio01 4.71 1.92E-05 104GCN4_YPD Drxt2 Keogh05 4.71 1.93E-05 70PHD1_YPD Drxt1 Keogh05 -4.71 1.94E-05 66STE12_YPD taf1-ts2_GCN5Huisinga04 4.7 1.95E-05 49SWI4_YPD SIN3 Hughes00 4.7 1.95E-05 153UME6_YPD RPD3_haploid Hughes00 4.7 1.95E-05 127SUT1_YPD spt3_E240K Huisinga04 -4.7 1.98E-05 59UME6_H2O2HiRpd3_del Bernstein02 4.7 1.98E-05 100YAP6_H2O2Hi isw2 Fazzio01 -4.68 2.05E-05 73RIM101_H2O2Loisw2_c.i._rpd3_c.i.Fazzio01 -4.68 2.05E-05 52MSN2_H2O2HiSSN6_haploid Hughes00 4.68 2.06E-05 77SWI6_YPD WT_V161R_L Chitikila_02 -4.68 2.07E-05 149YAP1_YPD IOC4 Hughes00 -4.68 2.07E-05 72NRG1_H2O2Hiisw2_c.i. Fazzio01 -4.68 2.08E-05 123RLM1_YPD YNG2 Krogan04 4.67 2.13E-05 55FKH2_H2O2Hi taf1-ts2_spt3 Huisinga04 -4.67 2.13E-05 103YAP6_H2O2Hi SSN6_haploid Hughes00 4.66 2.15E-05 75DAL81_RAPA WT_V161E Chitikila_02 -4.66 2.17E-05 89CIN5_H2O2Hi isw2_c.i. Fazzio01 -4.65 2.19E-05 79SKN7_H2O2Hi sas3D_taf1-ts2Durant06 4.65 2.19E-05 90SKN7_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 -4.65 2.19E-05 92MCM1_Alpha _SWC2_(VPS72)Krogan04 4.65 2.19E-05 102GCN4_SM gcn5_KQL Huisinga04 -4.65 2.23E-05 164HSF1_H2O2Hi VID21 Krogan04 4.65 2.23E-05 112MBP1_YPD DT_V71E Chitikila_02 -4.65 2.23E-05 123PUT3_H2O2Lo taf1-ts2_25C Huisinga04 -4.64 2.25E-05 84SWI4_YPD YNG2 Krogan04 4.64 2.27E-05 151STE12_Alpha htz1_hmr Meneghini03 4.64 2.29E-05 114SUM1_YPD isw2_rpd3 Fazzio01 -4.63 2.30E-05 59PUT3_H2O2Lo EAF5 Krogan04 4.63 2.30E-05 81DAL81_RAPA H4KQ Sabet04 4.63 2.33E-05 94YAP6_YPD isw2_rpd3 Fazzio01 -4.62 2.35E-05 87YAP6_YPD ARD1 Hughes00 -4.62 2.36E-05 91SWI4_YPD SIR2 Hughes00 -4.61 2.41E-05 155HAP4_YPD SPT8 Ingvarsdottir05 -4.61 2.44E-05 60SWI6_YPD YNG2 Mnaimneh_04 4.6 2.47E-05 153NDD1_YPD TAF2 Mnaimneh_04 4.6 2.47E-05 85SKN7_H2O2HiDrpd3 Keogh05 4.6 2.49E-05 87AFT2_H2O2Lo RSC8 Mnaimneh_04 4.6 2.49E-05 98PUT3_H2O2Lo ino80_+_0.1%_MMS_vs._ino80Attikum04 4.6 2.50E-05 67

MSN2_H2O2Hihtz1_del Mizuguch04 4.59 2.57E-05 77YAP7_H2O2Lo IOC4 Hughes00 -4.58 2.59E-05 151XBP1_H2O2Lo isw2_sin3 Fazzio01 -4.58 2.60E-05 65MSN4_H2O2Hitaf1-ts2_GCN5Huisinga04 4.58 2.61E-05 64YAP6_H2O2Lo sin3 Fazzio01 -4.58 2.61E-05 57SUM1_YPD rpd3_H4KQ_v_H4KQSabet04 -4.57 2.64E-05 54FKH2_YPD gcn5 Huisinga04 -4.57 2.68E-05 116CIN5_YPD DT_V161E Chitikila_02 -4.56 2.71E-05 142HSF1_H2O2Hi WT_V71E Chitikila_02 -4.56 2.72E-05 112MSN4_H2O2HiWT_V161R_K Chitikila_02 -4.56 2.72E-05 64GLN3_RAPA SIR4 Hughes00 4.55 2.76E-05 68SKN7_H2O2LoHda1_del Bernstein02 4.54 2.83E-05 182YAP7_H2O2Lo hht2_K914182327GMartin04 4.54 2.83E-05 126MBP1_H2O2HiSIR2 Hughes00 -4.54 2.84E-05 132GCN4_RAPA Dume1 Keogh05 4.54 2.85E-05 148UME6_H2O2Hisin3 Fazzio01 4.54 2.85E-05 98FKH2_YPD isw2_sin3 Fazzio01 4.54 2.86E-05 118SWI6_YPD WT_V161R_K Chitikila_02 -4.54 2.87E-05 141GCN4_SM spt3 Huisinga04 -4.53 2.89E-05 184PHD1_BUT90 Drxt1 Keogh05 -4.53 2.89E-05 104YAP6_YPD rpd3 Fazzio01 -4.53 2.90E-05 88GCN4_SM ISW1 Hughes00 -4.53 2.90E-05 189SOK2_BUT14 WT Durant06 -4.53 2.93E-05 69SWI6_YPD gcn5_KQL Huisinga04 -4.52 2.97E-05 132HSF1_H2O2Hi sir2 Meneghini03 4.51 3.05E-05 123NRG1_YPD isw2_ume6 Fazzio01 4.51 3.07E-05 70HSF1_H2O2Lotaf1-ts2 Durant06 4.51 3.08E-05 99MBP1_YPD isw2_rpd3 Fazzio01 4.5 3.14E-05 122HAP4_YPD ino80_del Mizuguch04 4.49 3.17E-05 67STE12_BUT14 RAD6_haploid Hughes00 -4.49 3.19E-05 127HAP4_YPD esa1-414 Durant06 4.49 3.20E-05 61MBP1_H2O2HiWT_TAF1_GCN5Huisinga04 -4.49 3.22E-05 132YAP6_H2O2Lo isw2_c.i. Fazzio01 -4.48 3.24E-05 57HSF1_H2O2Lorpd3_H3dN_v_H3dNSabet04 4.48 3.26E-05 98SKN7_H2O2LoUBP8 Ingvarsdottir05 4.48 3.28E-05 170REB1_YPD ARD1 Hughes00 4.48 3.31E-05 142MSN4_H2O2HiTAF2 Mnaimneh_04 4.48 3.31E-05 69NDD1_YPD EPL1 Mnaimneh_04 4.47 3.32E-05 85ROX1_YPD spt3 Huisinga04 -4.47 3.34E-05 66STE12_YPD Dsap30 Keogh05 -4.47 3.35E-05 53SWI4_YPD hht2_K27G Martin04 4.47 3.36E-05 125GCN4_SM WT_V161R_K Chitikila_02 -4.47 3.36E-05 176MBP1_H2O2HiDsds3 Keogh05 4.47 3.36E-05 126MGA1_YPD RSC8 Mnaimneh_04 -4.47 3.37E-05 63FKH2_YPD Drpd3 Keogh05 4.46 3.40E-05 112HAP4_YPD arp8 Attikum04 4.46 3.44E-05 48YAP1_YPD SIR2 Hughes00 4.46 3.45E-05 72HSF1_H2O2Losir2 Meneghini03 4.46 3.45E-05 100SWI6_YPD taf1-ts2_gcn5 Huisinga04 -4.45 3.47E-05 149SKN7_H2O2LoSSD1-V Kaeberlein04 4.45 3.54E-05 184HSF1_H2O2Lotaf1-ts2_GCN5Huisinga04 4.44 3.55E-05 95MBP1_YPD gcn5_KQL Huisinga04 -4.44 3.56E-05 109GCN4_RAPA taf1-ts2 Durant06 4.44 3.57E-05 159

SKN7_H2O2LoSWC6_(VPS71)Krogan04 4.44 3.58E-05 163CIN5_YPD arp8 Attikum04 -4.44 3.60E-05 116GCN4_RAPA sas3D_taf1-ts2Durant06 4.44 3.60E-05 146RIM101_H2O2Lorpd3 Fazzio01 -4.44 3.63E-05 52AFT2_H2O2Lo ISW1 Hughes00 -4.43 3.64E-05 96GCN4_SM YNG2 Mnaimneh_04 4.43 3.71E-05 189MSN2_H2O2HiWT_N69R Chitikila_02 -4.42 3.73E-05 73HSF1_H2O2Lospt10_del Xu05 4.42 3.74E-05 100UME6_YPD Drpd3 Keogh05 4.42 3.76E-05 121SKN7_H2O2Lohda1_del Bernstein_00_affydeletions4.42 3.79E-05 168YAP7_H2O2Lo hht2_K27G Martin04 4.41 3.82E-05 126GCN4_YPD arp8 Attikum04 -4.41 3.88E-05 65HAP1_YPD UBP8 Ingvarsdottir05 4.41 3.88E-05 127HSF1_H2O2Lohat1D_taf1-ts2Durant06 4.41 3.89E-05 87SWI4_YPD SWC6_(VPS71)Krogan04 4.4 3.91E-05 137YAP6_H2O2Hi ISW2 Hughes00 -4.4 3.91E-05 78YAP6_YPD UBP8 Ingvarsdottir05 4.4 3.94E-05 87SKN7_H2O2Lotaf1-ts2_gcn5_KQLHuisinga04 4.4 3.94E-05 152GCN4_RAPA WT_N69R Chitikila_02 -4.39 4.01E-05 151GCN4_RAPA Drxt2 Keogh05 4.39 4.01E-05 153HAP4_YPD ISW1 Hughes00 4.39 4.02E-05 67SWI4_YPD isw2_sin3_vs._sin3Fazzio01 -4.38 4.09E-05 152GCN4_RAPA snf2_rich_medium_experimentSudarsanam00 4.38 4.09E-05 158SUM1_YPD ISW1_ISW2 Hughes00 4.38 4.13E-05 59MBP1_H2O2HiDdep1 Keogh05 4.38 4.13E-05 127HAP1_YPD DT_V161R_L Chitikila_02 -4.37 4.19E-05 136GCR2_SM MED2_haploid Hughes00 -4.37 4.21E-05 54MBP1_YPD SIN3 Hughes00 4.36 4.28E-05 128NRG1_H2O2HiHda1_del Bernstein02 4.36 4.30E-05 124PHD1_BUT90 taf1-ts2_spt3 Huisinga04 -4.36 4.30E-05 103STE12_BUT90 htz1 Meneghini03 4.36 4.35E-05 76ASH1_BUT14 YNG2 Mnaimneh_04 4.35 4.41E-05 50MBP1_YPD HDA1 Hughes00 -4.35 4.41E-05 129SOK2_BUT14 esa1-414_taf1-ts2Durant06 4.34 4.49E-05 62PHD1_BUT90 esa1-414 Durant06 4.34 4.49E-05 96YAP7_H2O2Hi SIR2 Hughes00 4.34 4.50E-05 140ABF1_YPD gcn5D Durant06 4.34 4.53E-05 230CIN5_YPD sin3_del Bernstein_00_affydeletions-4.34 4.55E-05 139RPN4_H2O2Lohos3_del Bernstein_00_affydeletions4.34 4.56E-05 98HSF1_H2O2Logcn5D Durant06 4.34 4.57E-05 91HSF1_H2O2Losap30_del Bernstein_00_affydeletions4.33 4.58E-05 96ASH1_BUT14 VID21 Krogan04 4.33 4.58E-05 43SWI4_YPD SSD1-V Kaeberlein04 4.33 4.59E-05 154SUM1_YPD H3_1-28 Sabet04 4.33 4.62E-05 54MBP1_YPD taf1-ts2_gcn5_KQLHuisinga04 -4.33 4.65E-05 109HSF1_H2O2Lohos3_del Bernstein_00_affydeletions4.33 4.67E-05 95YAP6_H2O2Lo RPD3_haploid Hughes00 -4.32 4.69E-05 57SWI4_YPD ARP4 Mnaimneh_04 4.32 4.70E-05 156HAP1_YPD 0.1%_MMS Attikum04 -4.32 4.70E-05 116MBP1_YPD sin3 Fazzio01 4.32 4.71E-05 123SOK2_BUT14 ino80_del Mizuguch04 4.32 4.75E-05 72PHD1_BUT90 isw2_sin3 Fazzio01 -4.32 4.75E-05 103MGA1_YPD rpd3_H3dN_v_H3dNSabet04 -4.31 4.80E-05 61

GCN4_YPD 0.1%_MMS Attikum04 4.31 4.83E-05 67FKH1_YPD sin3 Fazzio01 4.31 4.86E-05 139HAP4_YPD H4KQ Sabet04 4.31 4.87E-05 62GCR2_SM sas3D_taf1-ts2Durant06 4.31 4.89E-05 49CIN5_YPD rpd3_c.i. Fazzio01 -4.29 5.04E-05 148GCN4_YPD WT_Null_L Chitikila_02 4.29 5.06E-05 72DAL81_RAPA taf1-ts2_GCN5Huisinga04 4.29 5.08E-05 91RCS1_H2O2LoARD1 Hughes00 4.29 5.12E-05 256SKN7_H2O2LoYNG2 Krogan04 4.28 5.17E-05 174XBP1_H2O2Lo isw2_c.i._rpd3_c.i.Fazzio01 -4.28 5.21E-05 65PHD1_BUT90 HDA1 Hughes00 4.28 5.23E-05 105HAP1_YPD taf1-ts2_GCN5Huisinga04 4.28 5.23E-05 133ASH1_BUT14 sas3D_taf1-ts2Durant06 4.28 5.24E-05 46YAP7_H2O2Hi HDA1 Hughes00 4.27 5.28E-05 139GCR2_SM taf1-ts2_GCN5Huisinga04 4.27 5.31E-05 53PUT3_H2O2Lo SWD2 Mnaimneh_04 4.27 5.36E-05 88NRG1_YPD ISW1_ISW2 Hughes00 4.26 5.41E-05 72NRG1_YPD HDA1 Hughes00 4.26 5.42E-05 72RPN4_H2O2LoWT_V161E Chitikila_02 4.25 5.51E-05 93XBP1_H2O2Lo TUP1_haploid Hughes00 4.25 5.53E-05 66AFT2_H2O2Hi ino80_del Mizuguch04 4.25 5.58E-05 61RPN4_H2O2Lohht2_K27G Martin04 4.25 5.59E-05 88PHD1_YPD sin3 Fazzio01 -4.25 5.60E-05 66DAL81_RAPA elp3D_taf1-ts2Durant06 4.25 5.62E-05 76GLN3_RAPA ubp10sir4 Orlandi04 -4.24 5.65E-05 51SWI6_YPD DT_WT Chitikila_02 -4.24 5.71E-05 147HAP1_YPD RPD3_haploid Hughes00 4.24 5.71E-05 137HAP4_YPD WT_WT Chitikila_02 4.24 5.72E-05 65YAP6_YPD hat1D_taf1-ts2Durant06 -4.24 5.73E-05 72RPN4_H2O2Logcn5D_taf1-ts2Durant06 4.24 5.75E-05 94MSN2_H2O2Hisir2 Meneghini03 4.23 5.77E-05 78SUM1_YPD spt3_E240K Huisinga04 -4.23 5.80E-05 51SWI4_YPD taf1-ts2_GCN5Huisinga04 4.23 5.86E-05 148HAP1_YPD delta_ssd1 Kaeberlein04 4.22 5.93E-05 141PHD1_BUT90 Set1_del Bernstein02 4.22 5.97E-05 106MBP1_YPD RPD3_haploid Hughes00 4.22 5.98E-05 130PUT3_H2O2Lo swi1_rich_medium_experimentSudarsanam00 4.21 6.06E-05 88CBF1_SM delta_ssd1 Kaeberlein04 4.21 6.07E-05 277HSF1_H2O2Lohat2_vs._hat1Rosaleny05 -4.21 6.14E-05 98SKN7_H2O2Lorpd3_H4KQ_v_H4KQSabet04 -4.21 6.14E-05 177YAP6_YPD taf1-ts2_SPT3 Huisinga04 -4.21 6.15E-05 85PUT3_H2O2Lo htz1_del Mizuguch04 4.2 6.18E-05 87NRG1_H2O2HiDT_V161E Chitikila_02 -4.2 6.22E-05 111YAP7_H2O2Lo HIR2 Hughes00 4.2 6.23E-05 152ACE2_YPD SIR3 Hughes00 4.2 6.24E-05 80ASH1_BUT14 hht2K9131823GMartin04 4.2 6.29E-05 41SKN7_YPD TUP1_haploid Hughes00 4.19 6.33E-05 66RLM1_YPD ARD1 Hughes00 -4.19 6.38E-05 55YAP6_H2O2Lo isw2 Fazzio01 -4.19 6.41E-05 57FKH2_YPD gcn5_KQL Huisinga04 -4.19 6.43E-05 104SKN7_H2O2LoH4KQ Sabet04 4.19 6.44E-05 177MSN2_H2O2HiTAF2 Mnaimneh_04 4.18 6.47E-05 77AFT2_H2O2Lo isw2_c.i. Fazzio01 -4.18 6.48E-05 95

FKH2_H2O2Hi Dsap30 Keogh05 4.18 6.51E-05 104UME6_YPD MOT1-14 Dasgupta02 4.18 6.52E-05 131SKN7_YPD taf1-ts2_GCN5Huisinga04 4.18 6.54E-05 67HAP1_YPD TAF2 Mnaimneh_04 4.17 6.62E-05 141SKN7_H2O2HiWT_N69S Chitikila_02 -4.17 6.71E-05 85ACE2_YPD esa1-414 Durant06 4.17 6.72E-05 73NRG1_YPD H4KQ Sabet04 4.17 6.75E-05 60RIM101_H2O2Losin3 Fazzio01 -4.16 6.79E-05 52MSN4_H2O2HiWT_V161E Chitikila_02 -4.16 6.81E-05 64PHD1_YPD Rpd3_del Bernstein02 -4.16 6.85E-05 65CIN5_YPD spt3 Huisinga04 -4.16 6.87E-05 145SKN7_H2O2LoWT_F182V Chitikila_02 4.15 6.93E-05 152SWI5_YPD taf1-ts2_gcn5 Huisinga04 4.15 6.94E-05 95NRG1_H2O2HiWT_V71R Chitikila_02 -4.15 6.95E-05 115SKN7_H2O2Lorpd3_c.i. Fazzio01 -4.15 6.95E-05 181XBP1_H2O2Lo YNG2 Mnaimneh_04 4.15 6.98E-05 68RPN4_H2O2Lohos2_del Bernstein_00_affydeletions4.15 7.03E-05 98RIM101_H2O2LoHDA1 Hughes00 4.14 7.11E-05 52MSN4_H2O2Hirsc30_null Angus-Hill_01 -4.14 7.17E-05 70GCR2_SM elp3D_taf1-ts2Durant06 4.14 7.18E-05 50DAL81_RAPA swi1_minimal_medium_experimentSudarsanam00 -4.13 7.26E-05 95HSF1_H2O2Hi _SWC2_(VPS72)Krogan04 4.13 7.26E-05 114DAL81_RAPA IOC4 Hughes00 -4.13 7.28E-05 94PUT3_H2O2Lo ISW2 Hughes00 -4.13 7.28E-05 88STE12_Alpha snf2_minimal_medium_experimentSudarsanam00 -4.13 7.28E-05 114MSN4_H2O2Hitaf1-ts2_SPT3 Huisinga04 4.13 7.30E-05 68SOK2_BUT14 isw2_c.i. Fazzio01 -4.13 7.30E-05 71YAP6_YPD sir4 Orlandi04 -4.13 7.31E-05 50MBP1_H2O2HiWT_N69R Chitikila_02 -4.13 7.34E-05 118SKN7_YPD esa1-414_taf1-ts2Durant06 4.13 7.39E-05 64XBP1_H2O2Lo hda1_del Bernstein_00_affydeletions4.12 7.50E-05 55SKN7_H2O2Hi elp3D_taf1-ts2Durant06 4.12 7.51E-05 73XBP1_H2O2Lo UBP8 Ingvarsdottir05 4.12 7.51E-05 65YAP1_YPD Dume1 Keogh05 4.12 7.58E-05 66PUT3_H2O2Lo H4_2-26 Sabet04 4.11 7.59E-05 85YAP6_YPD taf1-ts2 Durant06 -4.11 7.67E-05 89FKH2_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 -4.11 7.68E-05 96MBP1_YPD isw2_c.i. Fazzio01 4.1 7.92E-05 123FKH1_YPD taf1-ts2_spt3_E240KHuisinga04 -4.1 7.93E-05 127SWI4_YPD ubp10sir4 Orlandi04 -4.1 7.94E-05 107CBF1_SM IOC4 Hughes00 -4.09 7.95E-05 276SWI5_YPD BUR6 Geisberg_01 4.09 7.97E-05 94MGA1_YPD EPL1 Mnaimneh_04 -4.09 8.06E-05 62HSF1_H2O2LoHAT2 Hughes00 4.09 8.07E-05 99HAP1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -4.08 8.13E-05 136UME6_YPD esa1-414 Durant06 4.08 8.17E-05 116HSF1_H2O2LoSSN6_haploid Hughes00 4.08 8.19E-05 100RCS1_H2O2Hi ISW2 Hughes00 -4.08 8.27E-05 52NRG1_YPD isw2 Fazzio01 -4.08 8.27E-05 70GLN3_RAPA swi1_minimal_medium_experimentSudarsanam00 -4.08 8.28E-05 67SUM1_YPD H3KQ Sabet04 4.07 8.40E-05 54RLM1_YPD ubp10sir4 Orlandi04 -4.07 8.45E-05 37GCN4_RAPA sin3 Fazzio01 4.07 8.46E-05 155

ACE2_YPD SIR1 Hughes00 4.06 8.54E-05 78YAP1_YPD rpd3_H3dN_v_H3dNSabet04 4.06 8.60E-05 70MBP1_H2O2Hihht2K9131823GMartin04 4.06 8.67E-05 113MSN2_H2O2HiRSC8 Mnaimneh_04 4.05 8.72E-05 77GCN4_YPD Dsin3 Keogh05 4.05 8.74E-05 61HSF1_H2O2LoHTZ1 Krogan04 4.05 8.77E-05 91GCR2_SM hda1_del Bernstein_00_affydeletions4.05 8.78E-05 51PHD1_BUT90 isw2_c.i._rpd3_c.i.Fazzio01 -4.05 8.78E-05 102SKN7_YPD SWC6_(VPS71)Krogan04 4.05 8.81E-05 58GCR2_SM rpd3_H4KQ_v_H4KQSabet04 -4.05 8.83E-05 54GCR2_SM WT_V71R Chitikila_02 -4.05 8.87E-05 52SUT1_YPD WT Durant06 -4.04 8.93E-05 63DIG1_Alpha htz1 Meneghini03 4.04 8.93E-05 59SWI4_YPD htz1_del Mizuguch04 4.04 9.07E-05 156MBP1_H2O2Hi rpd3_c.i. Fazzio01 4.04 9.12E-05 126PUT3_H2O2Lo Rpd3_del Bernstein02 4.04 9.12E-05 88UME6_YPD YNG2 Mnaimneh_04 4.03 9.26E-05 130HAP4_YPD isw2_rpd3 Fazzio01 -4.03 9.26E-05 64UME6_YPD YNG2 Krogan04 4.03 9.30E-05 124NDD1_YPD SWC6_(VPS71)Krogan04 4.03 9.30E-05 76RPN4_H2O2Losnf2_minimal_medium_experimentSudarsanam00 4.02 9.38E-05 100MSN2_H2O2Hitaf1-ts2_gcn5_KQLHuisinga04 4.02 9.41E-05 65HAP1_YPD WT_N69R Chitikila_02 -4.02 9.47E-05 136MSN2_H2O2HiWT_V161R_L Chitikila_02 -4.02 9.48E-05 76PHD1_YPD swr1_del Mizuguch04 -4.01 9.57E-05 66GCN4_SM WT_V71E Chitikila_02 -4.01 9.66E-05 166HAP4_YPD RSC8 Mnaimneh_04 4.01 9.71E-05 67GLN3_RAPA HDA1 Hughes00 4 9.79E-05 68RTG3_RAPA ZDS1 Hughes00 4 9.89E-05 50HAP1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -4 9.91E-05 115ABF1_YPD RAD6_haploid Hughes00 3.99 0.0001 262ABF1_YPD YNG2 Mnaimneh_04 -3.99 0.0001 265ABF1_YPD isw2_rpd3 Fazzio01 3.99 0.0001 263ABF1_YPD taf1-ts2_gcn5 Huisinga04 3.99 0.0001 249PHD1_YPD ISW1 Hughes00 3.99 0.0001 67PHD1_YPD Dpho23 Keogh05 -3.99 0.0001 65RLM1_YPD esa1-414 Durant06 3.99 0.0001 48RLM1_YPD ume6_del Bernstein_00_affydeletions3.99 0.0001 47ROX1_YPD Set1_del Bernstein02 3.99 0.0001 66SKN7_YPD htz1_del Mizuguch04 3.99 0.0001 67SKN7_YPD rsc30_null Angus-Hill_01 -3.99 0.0001 67SKN7_YPD DT_Null Chitikila_02 3.99 0.0001 66STE12_YPD ARP4 Mnaimneh_04 3.99 0.0001 54STE12_YPD isw2_sin3 Fazzio01 -3.99 0.0001 54STE12_YPD Rpd3_del Bernstein02 -3.99 0.0001 52SUM1_YPD sas3D Durant06 -3.99 0.0001 42SUM1_YPD Dsap30 Keogh05 -3.99 0.0001 52SUT1_YPD isw2_rpd3_vs._rpd3Fazzio01 -3.99 0.0001 69SUT1_YPD WT_V161E Chitikila_02 -3.99 0.0001 65SWI4_YPD UBP8 Ingvarsdottir05 3.99 0.0001 143SWI4_YPD RPD3_haploid Hughes00 3.99 0.0001 156SWI4_YPD taf1-ts2 Durant06 3.99 0.0001 152SWI4_YPD sas3D_taf1-ts2Durant06 3.99 0.0001 142

SWI4_YPD DT_V161R_L Chitikila_02 -3.99 0.0001 148SWI5_YPD gcn5_KQL Huisinga04 3.99 0.0001 85SWI5_YPD taf1-ts2_gcn5_KQLHuisinga04 3.99 0.0001 81SWI6_YPD DM_vs._YPH250Rosaleny05 3.99 0.0001 144SWI6_YPD SAP30 Hughes00 3.99 0.0001 151SWI6_YPD ISW1 Hughes00 3.99 0.0001 153SWI6_YPD esa1-414_taf1-ts2Durant06 3.99 0.0001 141SWI6_YPD isw2_c.i. Fazzio01 3.99 0.0001 148SWI6_YPD isw2_rpd3 Fazzio01 3.99 0.0001 148SWI6_YPD htz1_del Mizuguch04 3.99 0.0001 153SWI6_YPD spt3 Huisinga04 -3.99 0.0001 148UME6_YPD sas3D_taf1-ts2Durant06 3.99 0.0001 113UME6_YPD Dsap30 Keogh05 3.99 0.0001 124YAP1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 3.99 0.0001 61YAP1_YPD SSD1-V Kaeberlein04 3.99 0.0001 70YAP6_YPD isw2 Fazzio01 -3.99 0.0001 88YAP6_YPD rpd3_c.i. Fazzio01 -3.99 0.0001 88YAP6_YPD Set1_del Bernstein02 3.99 0.0001 90CIN5_YPD esa1-414 Durant06 3.99 0.0001 137CIN5_YPD hat1D Durant06 -3.99 0.0001 106CIN5_YPD isw2_sin3 Fazzio01 -3.99 0.0001 148CIN5_YPD taf1-ts2_gcn5 Huisinga04 3.99 0.0001 144CBF1_SM htz1_sir2 Meneghini03 3.99 0.0001 272GCN4_SM UBP8 Ingvarsdottir05 -3.99 0.0001 177GCN4_SM WT_TAF1_GCN5Huisinga04 3.99 0.0001 187GCR2_SM hpa2D_taf1-ts2Durant06 3.99 0.0001 48GCR2_SM WT_F182V Chitikila_02 3.99 0.0001 51DAL81_RAPA snf2_minimal_medium_experimentSudarsanam00 -3.99 0.0001 95DAL81_RAPA isw2_rpd3_vs._rpd3Fazzio01 -3.99 0.0001 91DAL81_RAPA htz1_del Mizuguch04 3.99 0.0001 95DAL81_RAPA WT_WT Chitikila_02 -3.99 0.0001 93DAL81_RAPA taf1-ts2_gcn5 Huisinga04 3.99 0.0001 92DAL81_RAPA spt3 Huisinga04 -3.99 0.0001 91GCN4_RAPA WT_V161E Chitikila_02 -3.99 0.0001 151GCN4_RAPA hht2_K4914182327GMartin04 3.99 0.0001 137GCN4_RAPA taf1-ts2_GCN5Huisinga04 3.99 0.0001 150GLN3_RAPA snf2_minimal_medium_experimentSudarsanam00 -3.99 0.0001 67GLN3_RAPA IOC4 Hughes00 -3.99 0.0001 68AFT2_H2O2Hi swi1_rich_medium_experimentSudarsanam00 3.99 0.0001 61CIN5_H2O2Hi Set1_del Bernstein02 3.99 0.0001 80FKH2_H2O2Hi spt10_del Xu05 -3.99 0.0001 105FKH2_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 -3.99 0.0001 83FKH2_H2O2Hi HDA1 Hughes00 -3.99 0.0001 106FKH2_H2O2Hi SAP30 Hughes00 3.99 0.0001 106FKH2_H2O2Hi esa1-414 Durant06 3.99 0.0001 92FKH2_H2O2Hi Rpd3_del Bernstein02 3.99 0.0001 104HSF1_H2O2Hi hat1D Durant06 3.99 0.0001 94HSF1_H2O2Hi sas3D Durant06 3.99 0.0001 100MBP1_H2O2HiRpd3_del Bernstein02 3.99 0.0001 131MSN2_H2O2Hi0.1%_MMS Attikum04 3.99 0.0001 64MSN4_H2O2Hihat1_vs.YPH250Rosaleny05 3.99 0.0001 67MSN4_H2O2HiSSN6_haploid Hughes00 3.99 0.0001 69MSN4_H2O2Hihat1D_taf1-ts2Durant06 3.99 0.0001 59

MSN4_H2O2Hihtz1_sir2 Meneghini03 3.99 0.0001 70MSN4_H2O2HiWT_N69R Chitikila_02 -3.99 0.0001 62NRG1_H2O2Hihda1_del Bernstein_00_affydeletions3.99 0.0001 113SKN7_H2O2Hi taf1-ts2_SPT3 Huisinga04 3.99 0.0001 89SKN7_H2O2Hi YNG2 Mnaimneh_04 3.99 0.0001 98SKN7_H2O2Hi hpa2D_taf1-ts2Durant06 3.99 0.0001 71SKN7_H2O2Hi isw2_sin3 Fazzio01 -3.99 0.0001 95SKN7_H2O2HiWT_V161R_K Chitikila_02 -3.99 0.0001 85SKN7_H2O2HiWT_N69R Chitikila_02 -3.99 0.0001 86UME6_H2O2HiDsap30 Keogh05 3.99 0.0001 95YAP6_H2O2Hi rpd3_c.i. Fazzio01 -3.99 0.0001 73YAP7_H2O2Hi isw2_ume6 Fazzio01 3.99 0.0001 137YAP7_H2O2Hi Set1_del Bernstein02 3.99 0.0001 140YAP7_H2O2Hi hht2_K27G Martin04 3.99 0.0001 122YAP7_H2O2Hi H3KQ Sabet04 3.99 0.0001 138AFT2_H2O2Lo ubp10sir4 Orlandi04 3.99 0.0001 59CIN5_H2O2Lo HDA1 Hughes00 3.99 0.0001 124CIN5_H2O2Lo RPD3_haploid Hughes00 -3.99 0.0001 126CIN5_H2O2Lo htz1_hmr Meneghini03 -3.99 0.0001 124CIN5_H2O2Lo swr1 Meneghini03 -3.99 0.0001 109CIN5_H2O2Lo spt3 Huisinga04 -3.99 0.0001 124HSF1_H2O2LoWT_V71E Chitikila_02 -3.99 0.0001 91MBP1_H2O2Lotaf1-ts2_gcn5_KQLHuisinga04 -3.99 0.0001 50PUT3_H2O2Lo ubp10sir4 Orlandi04 3.99 0.0001 57PUT3_H2O2Lo ISW1_ISW2 Hughes00 -3.99 0.0001 88RIM101_H2O2Loisw2 Fazzio01 -3.99 0.0001 52RIM101_H2O2Logcn5 Huisinga04 3.99 0.0001 47RPN4_H2O2Lotaf1-ts2_SPT3 Huisinga04 3.99 0.0001 98RPN4_H2O2Loelp3D Durant06 3.99 0.0001 82RPN4_H2O2LoSet1_del Bernstein02 -3.99 0.0001 100RPN4_H2O2LoH3KQ Sabet04 -3.99 0.0001 98SKN7_H2O2Loubp10sir4 Orlandi04 -3.99 0.0001 121SKN7_H2O2LoSWR1 Krogan04 3.99 0.0001 173SKN7_H2O2Lo_SWC2_(VPS72)Krogan04 3.99 0.0001 174SKN7_H2O2LoMED2_haploid Hughes00 -3.99 0.0001 183SKN7_H2O2Loisw2_c.i. Fazzio01 -3.99 0.0001 181SKN7_H2O2Losap30_del Bernstein_00_affydeletions3.99 0.0001 166XBP1_H2O2Lo MOT1-42 Dasgupta02 3.99 0.0001 67YAP6_H2O2Lo hat1D Durant06 -3.99 0.0001 39YAP6_H2O2Lo spt3 Huisinga04 -3.99 0.0001 57YAP7_H2O2Lo spt10_del Xu05 3.99 0.0001 145YAP7_H2O2Lo H3_1-28 Sabet04 3.99 0.0001 147YAP7_H2O2Lo H3KQ Sabet04 3.99 0.0001 147DIG1_Alpha htz1_del Mizuguch04 3.99 0.0001 60MCM1_Alpha ISW1_ISW2 Hughes00 3.99 0.0001 106STE12_Alpha isw2_c.i. Fazzio01 3.99 0.0001 112ASH1_BUT14 htz1 Meneghini03 3.99 0.0001 48ASH1_BUT14 taf1-ts2_GCN5Huisinga04 3.99 0.0001 47SOK2_BUT14 DT_V161E Chitikila_02 -3.99 0.0001 66SOK2_BUT14 hht2K9131823GMartin04 3.99 0.0001 48SOK2_BUT14 rpd3_H4KQ_v_H4KQSabet04 -3.99 0.0001 65SOK2_BUT14 gcn5 Huisinga04 3.99 0.0001 68STE12_BUT14 sin3_del Bernstein_00_affydeletions-3.99 0.0001 118

STE12_BUT14 spt3_E240K Huisinga04 -3.99 0.0001 116PHD1_BUT90 0.1%_MMS Attikum04 -3.99 0.0001 76PHD1_BUT90 ino80_+_0.1%_MMS_vs._ino80Attikum04 -3.99 0.0001 73PHD1_BUT90 rpd3 Fazzio01 -3.99 0.0001 103FKH2_YPD taf1-ts2_spt3_E240KHuisinga04 -3.99 0.0001 104FKH2_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -3.99 0.0001 97FKH2_YPD HDA1 Hughes00 -3.99 0.0001 121FKH2_YPD SIR2 Hughes00 -3.99 0.0001 121FKH2_YPD htz1 Meneghini03 3.99 0.0001 119HAP1_YPD isw2_sin3 Fazzio01 -3.99 0.0001 136HAP1_YPD ume6_del Bernstein_00_affydeletions3.99 0.0001 135HAP1_YPD WT_V71E Chitikila_02 -3.99 0.0001 128HAP1_YPD WT_TAF1_SPT3Huisinga04 3.99 0.0001 140HAP4_YPD htz1_hmr Meneghini03 3.99 0.0001 63HAP4_YPD H4_2-26 Sabet04 -3.99 0.0001 62MBP1_YPD SIR2 Hughes00 -3.99 0.0001 130MBP1_YPD rpd3 Fazzio01 3.99 0.0001 123MBP1_YPD WT_V71R Chitikila_02 -3.99 0.0001 117MBP1_YPD DT_WT Chitikila_02 -3.99 0.0001 124MGA1_YPD RPD3_haploid Hughes00 -3.99 0.0001 61MGA1_YPD Rpd3_del Bernstein02 -3.99 0.0001 61MGA1_YPD H4KQ Sabet04 -3.99 0.0001 61NDD1_YPD RPD3_haploid Hughes00 3.99 0.0001 84NDD1_YPD WT_V161R_K Chitikila_02 -3.99 0.0001 81NDD1_YPD WT_N69R Chitikila_02 -3.99 0.0001 77ABF1_YPD SSN6_haploid Hughes00 -3.69 0.0002 263ABF1_YPD H4KQ Sabet04 -3.69 0.0002 261PHD1_YPD HDA1 Hughes00 3.69 0.0002 67PHD1_YPD rpd3 Fazzio01 -3.69 0.0002 66PHD1_YPD rpd3_c.i. Fazzio01 -3.69 0.0002 66PHD1_YPD isw2_sin3 Fazzio01 -3.69 0.0002 66PHD1_YPD DT_WT Chitikila_02 -3.69 0.0002 64PHD1_YPD rpd3_H4KQ_v_H4KQSabet04 -3.69 0.0002 62REB1_YPD RAD6_haploid Hughes00 3.69 0.0002 141REB1_YPD spt3_E240K Huisinga04 3.69 0.0002 133ROX1_YPD RAD6_haploid Hughes00 3.69 0.0002 67SKN7_YPD WT Durant06 -3.69 0.0002 63SKN7_YPD hda1_del Bernstein_00_affydeletions3.69 0.0002 56SKN7_YPD WT_V161E Chitikila_02 -3.69 0.0002 64SKN7_YPD YAF9 Krogan04 3.69 0.0002 62SUT1_YPD rpd3 Fazzio01 -3.69 0.0002 69SWI4_YPD sir4 Orlandi04 -3.69 0.0002 101SWI4_YPD ARD1 Hughes00 -3.69 0.0002 156SWI4_YPD rpd3_H4KQ_v_H4KQSabet04 -3.69 0.0002 151SWI4_YPD gcn5_KQL Huisinga04 -3.69 0.0002 129SWI5_YPD esa1-414_taf1-ts2Durant06 3.69 0.0002 88SWI5_YPD gcn5D_taf1-ts2Durant06 3.69 0.0002 89SWI6_YPD htz1 Meneghini03 3.69 0.0002 151SWI6_YPD WT_V71E Chitikila_02 -3.69 0.0002 132SWI6_YPD DT_V71E Chitikila_02 -3.69 0.0002 147SWI6_YPD YAF9 Krogan04 3.69 0.0002 149YAP6_YPD sas3D_taf1-ts2Durant06 -3.69 0.0002 77YAP6_YPD sin3_del Bernstein_00_affydeletions-3.69 0.0002 78

CIN5_YPD ARD1 Hughes00 -3.69 0.0002 149GCN4_SM taf1-ts2_spt3 Huisinga04 -3.69 0.0002 182GCR2_SM WT_V161R_K Chitikila_02 -3.69 0.0002 52DAL81_RAPA SIR2 Hughes00 3.69 0.0002 95DAL81_RAPA WT_N69S Chitikila_02 -3.69 0.0002 89GCN4_RAPA ume6_del Bernstein_00_affydeletions3.69 0.0002 156GCN4_RAPA spt3_E240K Huisinga04 3.69 0.0002 144GLN3_RAPA H4KQ Sabet04 3.69 0.0002 66GLN3_RAPA taf1-ts2_GCN5Huisinga04 3.69 0.0002 62FKH2_H2O2Hi isw2_rpd3 Fazzio01 3.69 0.0002 104HSF1_H2O2Hi arp8 Attikum04 -3.69 0.0002 100HSF1_H2O2Hi elp3D Durant06 3.69 0.0002 108HSF1_H2O2Hi gcn5D_taf1-ts2Durant06 3.69 0.0002 113HSF1_H2O2Hi hpa2D_taf1-ts2Durant06 3.69 0.0002 105HSF1_H2O2Hi H4KQ Sabet04 3.69 0.0002 122MBP1_H2O2HiWT_V71E Chitikila_02 -3.69 0.0002 111MSN2_H2O2Hihtz1 Meneghini03 3.69 0.0002 77MSN4_H2O2Hihtz1_del Mizuguch04 3.69 0.0002 69NRG1_H2O2Hiesa1-414 Durant06 3.69 0.0002 111NRG1_H2O2Hitaf1-ts2_GCN5Huisinga04 3.69 0.0002 113RCS1_H2O2Hi sir2 Meneghini03 3.69 0.0002 50RCS1_H2O2Hi hmr Meneghini03 3.69 0.0002 49RCS1_H2O2Hi H4_2-26 Sabet04 3.69 0.0002 50RCS1_H2O2Hi taf1-ts2_25C Huisinga04 -3.69 0.0002 49SKN7_H2O2HiUBP8 Ingvarsdottir05 3.69 0.0002 88SKN7_H2O2HiWT_V161R_L Chitikila_02 -3.69 0.0002 96UME6_H2O2HiARP4 Mnaimneh_04 3.69 0.0002 102YAP6_H2O2Hi spt3 Huisinga04 -3.69 0.0002 75YAP7_H2O2Hi hht2_K914182327GMartin04 3.69 0.0002 121AFT2_H2O2Lo snf2_minimal_medium_experimentSudarsanam00 3.69 0.0002 98CIN5_H2O2Lo MOT1-14 Dasgupta02 3.69 0.0002 127CIN5_H2O2Lo hda1_del Bernstein_00_affydeletions3.69 0.0002 112HSF1_H2O2Lotaf1-ts2_SPT3 Huisinga04 3.69 0.0002 98HSF1_H2O2Lo_SWC2_(VPS72)Krogan04 3.69 0.0002 94MBP1_H2O2Loisw2_rpd3 Fazzio01 3.69 0.0002 54RIM101_H2O2LoUBP8 Ingvarsdottir05 3.69 0.0002 52RIM101_H2O2LoRPD3_haploid Hughes00 -3.69 0.0002 52SKN7_H2O2Lohtz1_sir2 Meneghini03 3.69 0.0002 184SKN7_H2O2Loume6_del Bernstein_00_affydeletions3.69 0.0002 171SKN7_H2O2Logcn5_KQL Huisinga04 3.69 0.0002 151SKN7_H2O2Lospt3_E240K Huisinga04 -3.69 0.0002 157YAP6_H2O2Lo Rpd3_del Bernstein02 -3.69 0.0002 57ASH1_BUT14 htz1_del Mizuguch04 3.69 0.0002 50DIG1_BUT14 isw2_c.i. Fazzio01 3.69 0.0002 63DIG1_BUT14 YAF9 Krogan04 3.69 0.0002 62FKH1_YPD SIR2 Hughes00 -3.69 0.0002 139SOK2_BUT14 rpd3 Fazzio01 -3.69 0.0002 71STE12_BUT14 Drxt1 Keogh05 -3.69 0.0002 127STE12_BUT90 EPL1 Mnaimneh_04 3.69 0.0002 78ACE2_YPD WT_F182V Chitikila_02 3.69 0.0002 69GCN4_YPD sir4 Orlandi04 -3.69 0.0002 61GCN4_YPD taf1-ts2 Durant06 3.69 0.0002 74GCN4_YPD sas3D_taf1-ts2Durant06 3.69 0.0002 71

GCN4_YPD isw2_sin3_vs._sin3Fazzio01 -3.69 0.0002 74GCN4_YPD gcn5_KQL Huisinga04 -3.69 0.0002 70HAP1_YPD rpd3_c.i. Fazzio01 -3.69 0.0002 136HAP1_YPD isw2_rpd3_vs._rpd3Fazzio01 -3.69 0.0002 136HAP1_YPD WT_V71R Chitikila_02 -3.69 0.0002 134HAP4_YPD DT_V71R Chitikila_02 -3.69 0.0002 65HAP4_YPD hht2_K914182327GMartin04 3.69 0.0002 54MBP1_YPD htz1 Meneghini03 3.69 0.0002 129MBP1_YPD DT_V161E Chitikila_02 -3.69 0.0002 123MGA1_YPD HIR2 Hughes00 -3.69 0.0002 62NDD1_YPD htz1 Meneghini03 3.69 0.0002 84NDD1_YPD Rpd3_del Bernstein02 3.69 0.0002 84NRG1_YPD swr1 Meneghini03 -3.69 0.0002 52ABF1_YPD sas3D_taf1-ts2Durant06 3.52 0.0003 243PHD1_YPD RPD3_haploid Hughes00 -3.52 0.0003 67PHD1_YPD IES6 Hughes00 3.52 0.0003 67PHD1_YPD isw2_c.i. Fazzio01 -3.52 0.0003 66RLM1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -3.52 0.0003 38RLM1_YPD EAF7 Krogan04 3.52 0.0003 52RLM1_YPD YNG2 Mnaimneh_04 3.52 0.0003 55RLM1_YPD isw2_sin3 Fazzio01 -3.52 0.0003 54SKN7_YPD MOT1-14 Dasgupta02 3.52 0.0003 66SKN7_YPD Hda1_del Bernstein02 3.52 0.0003 65STE12_YPD 0.1%_MMS Attikum04 -3.52 0.0003 41STE12_YPD Drxt1 Keogh05 -3.52 0.0003 54SUM1_YPD spt10 Eriksson05 3.52 0.0003 56SUM1_YPD ISW1 Hughes00 3.52 0.0003 59SUT1_YPD esa1-414_taf1-ts2Durant06 3.52 0.0003 60SWI4_YPD hat1D_taf1-ts2Durant06 3.52 0.0003 126SWI4_YPD WT_F182V Chitikila_02 3.52 0.0003 129SWI5_YPD ARP4 Mnaimneh_04 3.52 0.0003 102SWI5_YPD H4KQ Sabet04 3.52 0.0003 93SWI6_YPD ARD1 Hughes00 -3.52 0.0003 152SWI6_YPD rpd3 Fazzio01 3.52 0.0003 148SWI6_YPD isw2_sin3_vs._sin3Fazzio01 -3.52 0.0003 148SWI6_YPD hht2_K4914182327GMartin04 3.52 0.0003 131UME6_YPD isw2_c.i._rpd3_c.i.Fazzio01 3.52 0.0003 124YAP1_YPD esa1-414 Durant06 3.52 0.0003 67YAP6_YPD ISW1 Hughes00 3.52 0.0003 91YAP6_YPD isw2_rpd3_vs._rpd3Fazzio01 -3.52 0.0003 87CIN5_YPD ARP4 Mnaimneh_04 3.52 0.0003 150CBF1_SM WT_F182V Chitikila_02 3.52 0.0003 232GCN4_SM swr1_del Mizuguch04 3.52 0.0003 188GCN4_SM hht2_K4914182327GMartin04 3.52 0.0003 166GCR2_SM ubp10sir4 Orlandi04 -3.52 0.0003 43GCR2_SM isw2_ume6 Fazzio01 -3.52 0.0003 52GCR2_SM sap30_del Bernstein_00_affydeletions3.52 0.0003 51DAL81_RAPA taf1-ts2_gcn5_KQLHuisinga04 3.52 0.0003 83GCN4_RAPA swi1_minimal_medium_experimentSudarsanam00 -3.52 0.0003 160GCN4_RAPA WT_V161R_K Chitikila_02 -3.52 0.0003 147GCN4_RAPA Dsap30 Keogh05 3.52 0.0003 151GLN3_RAPA taf1-ts2_SPT3 Huisinga04 3.52 0.0003 65GLN3_RAPA rpd3_c.i. Fazzio01 -3.52 0.0003 67

FKH2_H2O2Hi ARD1 Hughes00 -3.52 0.0003 105FKH2_H2O2Hi Dsin3 Keogh05 3.52 0.0003 87HSF1_H2O2Hi ubp10 Orlandi04 3.52 0.0003 91MBP1_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 3.52 0.0003 126MSN4_H2O2Hiino80_+_0.1%_MMS_vs._ino80Attikum04 3.52 0.0003 60MSN4_H2O2HiMOT1-14 Dasgupta02 3.52 0.0003 70NRG1_H2O2HiARD1 Hughes00 -3.52 0.0003 125NRG1_H2O2Hiswi1_rich_medium_experimentSudarsanam00 3.52 0.0003 124NRG1_H2O2HiWT_N69S Chitikila_02 -3.52 0.0003 114NRG1_H2O2Hirpd3_H4KQ_v_H4KQSabet04 -3.52 0.0003 120RCS1_H2O2Hi ubp10sir4 Orlandi04 3.52 0.0003 30HSF1_H2O2LoHDA1 Hughes00 -3.52 0.0003 100HSF1_H2O2LoDT_V161R_L Chitikila_02 3.52 0.0003 96RCS1_H2O2LoSSN6_haploid Hughes00 -3.52 0.0003 252RPN4_H2O2LoWT_V161R_L Chitikila_02 -3.52 0.0003 95RPN4_H2O2Logcn5 Huisinga04 3.52 0.0003 96SKN7_H2O2LoWT Durant06 -3.52 0.0003 173SKN7_H2O2Logcn5D Durant06 3.52 0.0003 161SKN7_H2O2Loino80_del Mizuguch04 3.52 0.0003 186YAP6_H2O2Lo SPT8 Ingvarsdottir05 -3.52 0.0003 50MCM1_Alpha isw2_c.i. Fazzio01 3.52 0.0003 104MCM1_Alpha DT_Null Chitikila_02 3.52 0.0003 104MCM1_Alpha YAF9 Krogan04 3.52 0.0003 101STE12_Alpha taf1-ts2_SPT3 Huisinga04 3.52 0.0003 111ASH1_BUT14 taf1-ts2 Durant06 3.52 0.0003 49ASH1_BUT14 htz1_sir2 Meneghini03 3.52 0.0003 48ASH1_BUT14 WT_N69R Chitikila_02 -3.52 0.0003 47FKH1_YPD SIN3 Hughes00 3.52 0.0003 141PHD1_BUT90 isw2_c.i. Fazzio01 -3.52 0.0003 103PHD1_BUT90 spt3_E240K Huisinga04 -3.52 0.0003 93FKH2_YPD ARD1 Hughes00 -3.52 0.0003 120ACE2_YPD SWR1 Krogan04 3.52 0.0003 74ACE2_YPD SWD2 Mnaimneh_04 3.52 0.0003 80GCN4_YPD htz1_sir2 Meneghini03 3.52 0.0003 73GCN4_YPD sir2 Meneghini03 3.52 0.0003 73HAP1_YPD hpa2D_taf1-ts2Durant06 3.52 0.0003 120HAP1_YPD isw2_ume6 Fazzio01 -3.52 0.0003 136HAP4_YPD taf1-ts2_spt3_E240KHuisinga04 3.52 0.0003 63HAP4_YPD 0.1%_MMS Attikum04 -3.52 0.0003 48HAP4_YPD isw2_sin3_vs._sin3Fazzio01 -3.52 0.0003 64HAP4_YPD htz1_del Mizuguch04 3.52 0.0003 67MBP1_YPD ISW1 Hughes00 3.52 0.0003 130NRG1_YPD ISW1 Hughes00 3.52 0.0003 71NRG1_YPD YNG2 Mnaimneh_04 3.52 0.0003 72NRG1_YPD MOT1-42 Dasgupta02 3.52 0.0003 72NRG1_YPD swi1_rich_medium_experimentSudarsanam00 3.52 0.0003 72NRG1_YPD Drxt1 Keogh05 -3.52 0.0003 70ABF1_YPD TUP1_haploid Hughes00 -3.39 0.0004 263ABF1_YPD esa1-414 Durant06 -3.39 0.0004 248ABF1_YPD spt3_E240K Huisinga04 3.39 0.0004 244ROX1_YPD taf1-ts2_SPT3 Huisinga04 -3.39 0.0004 64ROX1_YPD Hda1_del Bernstein02 3.39 0.0004 67SKN7_YPD UBP8 Hughes00 3.39 0.0004 66

SKN7_YPD WT_N69R Chitikila_02 -3.39 0.0004 63SUM1_YPD DT_V71E Chitikila_02 -3.39 0.0004 54SUT1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -3.39 0.0004 68SWI4_YPD DM_vs._YPH250Rosaleny05 3.39 0.0004 143SWI4_YPD TAF2 Mnaimneh_04 3.39 0.0004 156SWI6_YPD 0.1%_MMS Attikum04 -3.39 0.0004 128SWI6_YPD UBP8 Hughes00 3.39 0.0004 152SWI6_YPD DT_V161R_L Chitikila_02 -3.39 0.0004 146UME6_YPD Drxt1 Keogh05 -3.39 0.0004 130YAP6_YPD ubp10sir4 Orlandi04 -3.39 0.0004 54YAP6_YPD spt3_E240K Huisinga04 -3.39 0.0004 82CIN5_YPD SIR2 Hughes00 3.39 0.0004 149CIN5_YPD Set1_del Bernstein02 3.39 0.0004 147CBF1_SM SIR2 Hughes00 3.39 0.0004 278GCR2_SM UBP8 Ingvarsdottir05 3.39 0.0004 47GCR2_SM sir4 Orlandi04 -3.39 0.0004 43GCR2_SM WT_N69S Chitikila_02 -3.39 0.0004 48DAL81_RAPA HDA1 Hughes00 3.39 0.0004 94DAL81_RAPA YNG2 Mnaimneh_04 3.39 0.0004 95GLN3_RAPA taf1-ts2 Durant06 3.39 0.0004 66MSN4_RAPA SIN3 Hughes00 -3.39 0.0004 54FKH2_H2O2Hi Dsds3 Keogh05 3.39 0.0004 99HSF1_H2O2Hi HAT2 Hughes00 3.39 0.0004 122HSF1_H2O2Hi Hda1_del Bernstein02 3.39 0.0004 124MSN2_H2O2Hihat1_vs.YPH250Rosaleny05 3.39 0.0004 76MSN2_H2O2Hisap30_del Bernstein_00_affydeletions3.39 0.0004 69SKN7_H2O2HiSPT8 Ingvarsdottir05 -3.39 0.0004 86YAP6_H2O2Hi rpd3 Fazzio01 -3.39 0.0004 73YAP6_H2O2Hi swr1_del Mizuguch04 -3.39 0.0004 79AFT2_H2O2Lo swr1 Meneghini03 -3.39 0.0004 78CIN5_H2O2Lo isw2_rpd3 Fazzio01 -3.39 0.0004 125HSF1_H2O2LoSIR1 Hughes00 3.39 0.0004 99HSF1_H2O2LoWT_V161R_K Chitikila_02 -3.39 0.0004 91HSF1_H2O2LoWT_N69R Chitikila_02 -3.39 0.0004 93HSF1_H2O2LoWT_V71R Chitikila_02 -3.39 0.0004 95MBP1_H2O2LoSWC6_(VPS71)Krogan04 3.39 0.0004 54SKN7_H2O2LoDrpd3 Keogh05 3.39 0.0004 165YAP6_H2O2Lo SPT3 Ingvarsdottir05 -3.39 0.0004 50YAP6_H2O2Lo hda1_del Bernstein_00_affydeletions3.39 0.0004 50YAP7_H2O2Lo H4_2-26 Sabet04 3.39 0.0004 146DIG1_Alpha sas3D Durant06 -3.39 0.0004 43STE12_Alpha htz1_sir2 Meneghini03 -3.39 0.0004 114STE12_Alpha Dsap30 Keogh05 -3.39 0.0004 111STE12_Alpha spt3_E240K Huisinga04 -3.39 0.0004 98ASH1_BUT14 WT_V161E Chitikila_02 -3.39 0.0004 47SOK2_BUT14 ino80 Attikum04 3.39 0.0004 50STE12_BUT14 sir2 Meneghini03 -3.39 0.0004 127STE12_BUT14 sap30_del Bernstein_00_affydeletions-3.39 0.0004 120PHD1_BUT90 taf1-ts2_gcn5 Huisinga04 3.39 0.0004 104STE12_BUT90 spt3_E240K Huisinga04 -3.39 0.0004 67FKH2_YPD htz1_hmr Meneghini03 3.39 0.0004 117ACE2_YPD SSD1-V Kaeberlein04 3.39 0.0004 80ACE2_YPD H4KQ Sabet04 3.39 0.0004 77

HAP1_YPD snf2_minimal_medium_experimentSudarsanam00 3.39 0.0004 141HAP1_YPD htz1_sir2 Meneghini03 3.39 0.0004 134HAP4_YPD rpd3_c.i. Fazzio01 -3.39 0.0004 64HAP4_YPD htz1 Meneghini03 3.39 0.0004 63MBP1_YPD EPL1 Mnaimneh_04 3.39 0.0004 130MBP1_YPD WT_V161R_L Chitikila_02 -3.39 0.0004 124MGA1_YPD SIR3 Hughes00 -3.39 0.0004 62NDD1_YPD htz1_hmr Meneghini03 3.39 0.0004 83NRG1_YPD sas3D Durant06 -3.39 0.0004 50NRG1_YPD gcn5 Huisinga04 3.39 0.0004 65PHD1_YPD taf1-ts2_spt3 Huisinga04 -3.3 0.0005 65PHD1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -3.3 0.0005 65PHD1_YPD isw2_ume6 Fazzio01 3.3 0.0005 66PHD1_YPD htz1_del Mizuguch04 -3.3 0.0005 67STE12_YPD rpd3_H4KQ_v_H4KQSabet04 -3.3 0.0005 51STE12_YPD Drpd3 Keogh05 -3.3 0.0005 51SWI4_YPD spt10_del Xu05 -3.3 0.0005 153SWI4_YPD Deaf3 Keogh05 3.3 0.0005 146SWI6_YPD ARP4 Mnaimneh_04 3.3 0.0005 153UME6_YPD gcn5D_taf1-ts2Durant06 3.3 0.0005 118YAP1_YPD UBP8 Hughes00 3.3 0.0005 72YAP6_YPD Rpd3_del Bernstein02 -3.3 0.0005 91YAP6_YPD YNG2 Krogan04 3.3 0.0005 86DAL81_RAPA SWD2 Mnaimneh_04 3.3 0.0005 95DAL81_RAPA esa1-414 Durant06 3.3 0.0005 86DAL81_RAPA WT_V161R_K Chitikila_02 -3.3 0.0005 91DAL82_RAPA SIR2 Hughes00 3.3 0.0005 56GLN3_RAPA isw2_sin3 Fazzio01 -3.3 0.0005 67RTG3_RAPA taf1-ts2_SPT3 Huisinga04 3.3 0.0005 50AFT2_H2O2Hi sap30_del Bernstein_00_affydeletions3.3 0.0005 53FKH2_H2O2Hi rpd3 Fazzio01 3.3 0.0005 103HSF1_H2O2Hi H3_1-28 Sabet04 -3.3 0.0005 122MBP1_H2O2Hihtz1 Meneghini03 3.3 0.0005 131MSN2_H2O2HiH3KQ Sabet04 3.3 0.0005 74MSN4_H2O2HiEPL1 Mnaimneh_04 3.3 0.0005 70MSN4_H2O2HiRSC8 Mnaimneh_04 3.3 0.0005 70NRG1_H2O2Hi_SWC2_(VPS72)Krogan04 3.3 0.0005 116NRG1_H2O2HiHST3 Hughes00 3.3 0.0005 123NRG1_H2O2HiWT_V161R_K Chitikila_02 -3.3 0.0005 114UME6_H2O2Hiisw2_c.i._rpd3_c.i.Fazzio01 3.3 0.0005 97UME6_H2O2HiYNG2 Krogan04 3.3 0.0005 94UME6_H2O2HiDrxt2 Keogh05 3.3 0.0005 91AFT2_H2O2Lo WT_TAF1_SPT3Huisinga04 3.3 0.0005 93CIN5_H2O2Lo UBP8 Ingvarsdottir05 3.3 0.0005 117CIN5_H2O2Lo MOT1-42 Dasgupta02 3.3 0.0005 127PUT3_H2O2Lo VID21 Krogan04 3.3 0.0005 81RPN4_H2O2Lohht2_K49141823GMartin04 3.3 0.0005 87SKN7_H2O2LoRPD3_haploid Hughes00 3.3 0.0005 181XBP1_H2O2Lo sin3_del Bernstein_00_affydeletions-3.3 0.0005 53DIG1_Alpha rpd3_del Sabet04 -3.3 0.0005 56MCM1_Alpha ISW1 Hughes00 3.3 0.0005 106STE12_Alpha arp8 Attikum04 -3.3 0.0005 87STE12_Alpha rpd3_H4KQ_v_H4KQSabet04 -3.3 0.0005 109

ASH1_BUT14 WT_V161R_L Chitikila_02 -3.3 0.0005 47SOK2_BUT14 ARP4 Mnaimneh_04 3.3 0.0005 72SOK2_BUT14 VID21 Krogan04 3.3 0.0005 67STE12_BUT14 0.1%_MMS Attikum04 -3.3 0.0005 108PHD1_BUT90 delta_ssd1 Kaeberlein04 3.3 0.0005 105PHD1_BUT90 Drxt2 Keogh05 -3.3 0.0005 101STE12_BUT90 isw2_sin3_vs._sin3Fazzio01 -3.3 0.0005 76FKH2_YPD 0.1%_MMS Attikum04 -3.3 0.0005 97ACE2_YPD MED2_haploid Hughes00 -3.3 0.0005 80HAP1_YPD Hda1_del Bernstein02 3.3 0.0005 140HAP1_YPD Drxt1 Keogh05 -3.3 0.0005 140HAP4_YPD swr1_del Mizuguch04 -3.3 0.0005 66MBP1_YPD WT_V161E Chitikila_02 -3.3 0.0005 124MBP1_YPD YNG2 Krogan04 3.3 0.0005 127MCM1_YPD isw2_c.i. Fazzio01 3.3 0.0005 73NRG1_YPD RAD6_haploid Hughes00 3.3 0.0005 72PHD1_YPD ume6 Fazzio01 3.22 0.0006 66PHD1_YPD ino80_del Mizuguch04 3.22 0.0006 67RLM1_YPD UBP8 Ingvarsdottir05 3.22 0.0006 52SUM1_YPD sap30_del Bernstein_00_affydeletions-3.22 0.0006 41SWI4_YPD _SWC2_(VPS72)Krogan04 3.22 0.0006 149SWI5_YPD taf1-ts2 Durant06 3.22 0.0006 98SWI5_YPD sas3D_taf1-ts2Durant06 3.22 0.0006 88SWI6_YPD SSD1-V Kaeberlein04 3.22 0.0006 150SWI6_YPD Rpd3_del Bernstein02 3.22 0.0006 151UME6_YPD TUP1_haploid Hughes00 3.22 0.0006 130UME6_YPD H4KQ Sabet04 3.22 0.0006 129CIN5_YPD WT_V71E Chitikila_02 -3.22 0.0006 127GCN4_SM WT_N69S Chitikila_02 -3.22 0.0006 174DAL81_RAPA IES6 Hughes00 -3.22 0.0006 94DAL81_RAPA isw2_c.i. Fazzio01 -3.22 0.0006 91DAL81_RAPA isw2_sin3_vs._sin3Fazzio01 -3.22 0.0006 91DAL81_RAPA htz1_sir2 Meneghini03 3.22 0.0006 91GCN4_RAPA UBP8 Ingvarsdottir05 -3.22 0.0006 149MSN4_RAPA Rpd3_del Bernstein02 -3.22 0.0006 54HSF1_H2O2Hi swr1_del Mizuguch04 3.22 0.0006 124MBP1_H2O2HiDT_N69S Chitikila_02 -3.22 0.0006 121MSN2_H2O2Hiisw2_sin3_vs._sin3Fazzio01 -3.22 0.0006 75MSN4_H2O2HiUBP8 Hughes00 3.22 0.0006 69NRG1_H2O2HiWT_V161R_L Chitikila_02 -3.22 0.0006 115RCS1_H2O2Hi swr1 Meneghini03 -3.22 0.0006 41YAP6_H2O2Hi Drco1 Keogh05 3.22 0.0006 77YAP6_H2O2Hi Drxt1 Keogh05 -3.22 0.0006 78HSF1_H2O2LoRpd3_del Bernstein02 3.22 0.0006 101MBP1_H2O2LoRPD3_haploid Hughes00 3.22 0.0006 57MBP1_H2O2LoHda1_del Bernstein02 -3.22 0.0006 57PUT3_H2O2Lo SPT3 Ingvarsdottir05 3.22 0.0006 69RIM101_H2O2Loisw2_rpd3_vs._rpd3Fazzio01 -3.22 0.0006 52SKN7_H2O2LoDM_vs._YPH250Rosaleny05 3.22 0.0006 171YAP6_H2O2Lo Hda1_del Bernstein02 3.22 0.0006 57YAP7_H2O2Lo rpd3 Fazzio01 -3.22 0.0006 148STE12_Alpha sir2 Meneghini03 -3.22 0.0006 114STE12_Alpha H4_2-26 Sabet04 -3.22 0.0006 109

ASH1_BUT14 taf1-ts2_SPT3 Huisinga04 3.22 0.0006 49ASH1_BUT14 EPL1 Mnaimneh_04 3.22 0.0006 50FKH1_YPD HST3 Hughes00 -3.22 0.0006 141PHD1_BUT90 UBP8 Ingvarsdottir05 3.22 0.0006 98PHD1_BUT90 ISW1 Hughes00 3.22 0.0006 106PHD1_BUT90 hda1_del Bernstein_00_affydeletions3.22 0.0006 90HAP1_YPD taf1-ts2 Durant06 3.22 0.0006 141HAP4_YPD sir2 Meneghini03 3.22 0.0006 62NRG1_YPD taf1-ts2 Durant06 -3.22 0.0006 69PHD1_YPD hda1_del Bernstein_00_affydeletions3.15 0.0007 60SKN7_YPD SSD1-V Kaeberlein04 3.15 0.0007 67CBF1_SM HIR2 Hughes00 3.15 0.0007 274GCN4_SM DM_vs._YPH250Rosaleny05 3.15 0.0007 175GCN4_SM sap30_del Bernstein_00_affydeletions3.15 0.0007 182GCR2_SM DT_V161R_K Chitikila_02 -3.15 0.0007 53DAL82_RAPA isw2_c.i._rpd3_c.i.Fazzio01 -3.15 0.0007 54GCN4_RAPA snf2_minimal_medium_experimentSudarsanam00 -3.15 0.0007 160GCN4_RAPA WT_V71E Chitikila_02 -3.15 0.0007 142MSN4_RAPA SSD1-V Kaeberlein04 -3.15 0.0007 54RTG3_RAPA SIR2 Hughes00 3.15 0.0007 52FKH2_H2O2Hi Drxt2 Keogh05 3.15 0.0007 103HSF1_H2O2Hi hpa2D Durant06 -3.15 0.0007 102MSN2_H2O2HiARP4 Mnaimneh_04 3.15 0.0007 78MSN2_H2O2HiYNG2 Krogan04 3.15 0.0007 75MSN4_H2O2Hi_SWC2_(VPS72)Krogan04 3.15 0.0007 64REB1_H2O2Hi spt3 Huisinga04 3.15 0.0007 56SKN7_H2O2Hi hat1_vs.YPH250Rosaleny05 3.15 0.0007 92SKN7_H2O2Hi hat2_vs._YPH250Rosaleny05 3.15 0.0007 93YAP7_H2O2Hi ISW2 Hughes00 3.15 0.0007 141AFT2_H2O2Lo ino80_+_0.1%_MMS_vs._ino80Attikum04 3.15 0.0007 73AFT2_H2O2Lo rsc3-2 Angus-Hill_01 3.15 0.0007 96MBP1_H2O2Lotaf1-ts2_gcn5 Huisinga04 -3.15 0.0007 54PUT3_H2O2Lo HDA1 Hughes00 3.15 0.0007 88RCS1_H2O2Lohos2_del Bernstein_00_affydeletions3.15 0.0007 247XBP1_H2O2Lo WT Durant06 -3.15 0.0007 66XBP1_H2O2Lo sin3 Fazzio01 -3.15 0.0007 65STE12_Alpha isw2_sin3 Fazzio01 -3.15 0.0007 112ASH1_BUT14 RSC8 Mnaimneh_04 3.15 0.0007 50ASH1_BUT14 taf1-ts2_gcn5_KQLHuisinga04 3.15 0.0007 38FKH1_YPD TUP1_haploid Hughes00 -3.15 0.0007 139SOK2_BUT14 YNG2 Mnaimneh_04 3.15 0.0007 72PHD1_BUT90 hat2_vs._YPH250Rosaleny05 3.15 0.0007 98ACE2_YPD EPL1 Mnaimneh_04 3.15 0.0007 80MGA1_YPD isw2_rpd3 Fazzio01 -3.15 0.0007 60NRG1_YPD sir2 Meneghini03 3.15 0.0007 71NRG1_YPD sap30_del Bernstein_00_affydeletions-3.15 0.0007 54RLM1_YPD taf1-ts2_spt3 Huisinga04 -3.09 0.0008 53SKN7_YPD delta_ssd1 Kaeberlein04 3.09 0.0008 67SKN7_YPD RPD3_haploid Hughes00 3.09 0.0008 65STE12_YPD hht2_K4914182327GMartin04 -3.09 0.0008 43SUM1_YPD Dsin3 Keogh05 -3.09 0.0008 49UME6_YPD taf1-ts2 Durant06 3.09 0.0008 130CBF1_SM SSD1-V Kaeberlein04 3.09 0.0008 278

CBF1_SM SIR3 Hughes00 3.09 0.0008 279CBF1_SM WT_V161R_K Chitikila_02 -3.09 0.0008 253CBF1_SM Dsds3 Keogh05 3.09 0.0008 242GCR2_SM hat1D_taf1-ts2Durant06 3.09 0.0008 45GCR2_SM taf1-ts2_gcn5 Huisinga04 3.09 0.0008 52GLN3_RAPA hpa2D_taf1-ts2Durant06 3.09 0.0008 50MSN4_H2O2HiRpd3_del Bernstein02 3.09 0.0008 69MSN4_H2O2Hirpd3_H4KQ_v_H4KQSabet04 -3.09 0.0008 65SKN7_H2O2Hi YNG2 Krogan04 3.09 0.0008 91AFT2_H2O2Lo Rpd3_del Bernstein02 3.09 0.0008 97HSF1_H2O2Loarp8 Attikum04 -3.09 0.0008 84HSF1_H2O2LoH4KQ Sabet04 3.09 0.0008 98PUT3_H2O2Lo swr1 Meneghini03 -3.09 0.0008 72RIM101_H2O2LoIES6 Hughes00 3.09 0.0008 53XBP1_H2O2Lo spt3 Huisinga04 -3.09 0.0008 65YAP6_H2O2Lo isw2_rpd3_vs._rpd3Fazzio01 -3.09 0.0008 57YAP7_H2O2Lo Set1_del Bernstein02 3.09 0.0008 150DIG1_Alpha htz1_hmr Meneghini03 3.09 0.0008 59DIG1_Alpha Rpd3_del Bernstein02 -3.09 0.0008 57DIG1_Alpha spt3_E240K Huisinga04 -3.09 0.0008 47ASH1_BUT14 H4KQ Sabet04 3.09 0.0008 47FKH1_YPD Dpho23 Keogh05 3.09 0.0008 141FKH2_YPD spt10_del Xu05 -3.09 0.0008 120FKH2_YPD HST3 Hughes00 -3.09 0.0008 120MBP1_YPD DT_N69R Chitikila_02 -3.09 0.0008 121MGA1_YPD Dsds3 Keogh05 -3.09 0.0008 55MGA1_YPD Dsin3 Keogh05 -3.09 0.0008 56NDD1_YPD _SWC2_(VPS72)Krogan04 3.09 0.0008 81NRG1_YPD isw2_rpd3_vs._rpd3Fazzio01 -3.09 0.0008 70PHD1_YPD hht2K9131823GMartin04 3.04 0.0009 47RLM1_YPD isw2_c.i. Fazzio01 -3.04 0.0009 54YAP6_YPD UBP8 Hughes00 3.04 0.0009 91CIN5_YPD spt3_E240K Huisinga04 -3.04 0.0009 128DAL81_RAPA taf1-ts2_SPT3 Huisinga04 3.04 0.0009 93DAL81_RAPA DT_WT Chitikila_02 -3.04 0.0009 92DAL82_RAPA sap30_del Bernstein_00_affydeletions-3.04 0.0009 50DAL82_RAPA WT_TAF1_GCN5Huisinga04 -3.04 0.0009 56GLN3_RAPA WT_V71E Chitikila_02 -3.04 0.0009 62MSN4_H2O2HiARP4 Mnaimneh_04 3.04 0.0009 70NRG1_H2O2HiHDA1 Hughes00 3.04 0.0009 126RCS1_H2O2Hi hht2_K4G Martin04 -3.04 0.0009 36REB1_H2O2Hi hht2_K914182327GMartin04 3.04 0.0009 50SKN7_H2O2Hi _SWC2_(VPS72)Krogan04 3.04 0.0009 94YAP6_H2O2Hi spt3_E240K Huisinga04 -3.04 0.0009 70YAP7_H2O2Hi TUP1_haploid Hughes00 3.04 0.0009 139SKN7_H2O2Loswi1_minimal_medium_experimentSudarsanam00 -3.04 0.0009 185XBP1_H2O2Lo rpd3_H4KQ_v_H4KQSabet04 -3.04 0.0009 56YAP6_H2O2Lo WT Durant06 -3.04 0.0009 52YAP7_H2O2Lo SSN6_haploid Hughes00 3.04 0.0009 150ASH1_BUT14 ZDS1 Hughes00 3.04 0.0009 50ASH1_BUT14 WT_V161R_K Chitikila_02 -3.04 0.0009 47FKH1_YPD Rpd3_del Bernstein02 3.04 0.0009 140SOK2_BUT14 sap30_del Bernstein_00_affydeletions-3.04 0.0009 59

STE12_BUT90 SIN3 Hughes00 3.04 0.0009 78STE12_BUT90 esa1-414 Durant06 3.04 0.0009 75FKH2_YPD taf1-ts2_spt3 Huisinga04 -3.04 0.0009 115HAP4_YPD TAF2 Mnaimneh_04 3.04 0.0009 67HAP4_YPD hht2K9131823GMartin04 -3.04 0.0009 54NDD1_YPD DT_Null Chitikila_02 3.04 0.0009 82NRG1_YPD DT_V161E Chitikila_02 -3.04 0.0009 64ABF1_YPD UBP8 Hughes00 -2.99 0.001 265ROX1_YPD taf1-ts2 Durant06 -2.99 0.001 65SKN7_YPD taf1-ts2_gcn5_KQLHuisinga04 2.99 0.001 58SUM1_YPD spt10_del Xu05 -2.99 0.001 58SUM1_YPD MED2_haploid Hughes00 2.99 0.001 59SUT1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -2.99 0.001 46SUT1_YPD YNG2 Mnaimneh_04 2.99 0.001 67SWI5_YPD EPL1 Mnaimneh_04 2.99 0.001 102YAP1_YPD HDA1 Hughes00 2.99 0.001 72YAP1_YPD htz1_sir2 Meneghini03 2.99 0.001 67CBF1_SM RSC8 Mnaimneh_04 2.99 0.001 279GCN4_SM snf2_minimal_medium_experimentSudarsanam00 -2.99 0.001 189GCN4_SM DT_WT Chitikila_02 -2.99 0.001 181DAL81_RAPA isw2_sin3 Fazzio01 -2.99 0.001 91GLN3_RAPA H3_1-28 Sabet04 2.99 0.001 66MSN4_RAPA sap30_del Bernstein_00_affydeletions-2.99 0.001 50RTG3_RAPA sas3D_taf1-ts2Durant06 2.99 0.001 44HSF1_H2O2Hi hos2_del Bernstein_00_affydeletions2.99 0.001 119MSN2_H2O2HiYNG2 Mnaimneh_04 2.99 0.001 77MSN2_H2O2HiDpho23 Keogh05 2.99 0.001 77MSN4_H2O2HiYNG2 Krogan04 2.99 0.001 66NRG1_H2O2HiDT_WT Chitikila_02 -2.99 0.001 119AFT2_H2O2Lo YNG2 Mnaimneh_04 2.99 0.001 96CIN5_H2O2Lo SGF11 Ingvarsdottir05 2.99 0.001 107CIN5_H2O2Lo sap30_del Bernstein_00_affydeletions-2.99 0.001 110HSF1_H2O2LoSPT3 Ingvarsdottir05 2.99 0.001 90HSF1_H2O2Losin3_del Bernstein_00_affydeletions2.99 0.001 96RPN4_H2O2LoWT_F182V Chitikila_02 2.99 0.001 92RPN4_H2O2LoH3_1-28 Sabet04 -2.99 0.001 98SKN7_H2O2LoSIR1 Hughes00 2.99 0.001 184SKN7_H2O2Lotaf1-ts2_25C Huisinga04 2.99 0.001 159XBP1_H2O2Lo DT_V161R_L Chitikila_02 2.99 0.001 63FKH2_YPD isw2_rpd3 Fazzio01 2.99 0.001 119HAP1_YPD BUR6 Geisberg_01 2.99 0.001 135HAP1_YPD WT_N69S Chitikila_02 -2.99 0.001 132HAP4_YPD DM_vs._YPH250Rosaleny05 -2.99 0.001 60MBP1_YPD WT_V161R_K Chitikila_02 -2.99 0.001 119MBP1_YPD WT_TAF1_GCN5Huisinga04 -2.99 0.001 128NDD1_YPD taf1-ts2_25C Huisinga04 2.99 0.001 80PHD1_YPD DT_V161E Chitikila_02 -2.95 0.0011 63SKN7_YPD taf1-ts2 Durant06 2.95 0.0011 67SWI5_YPD ino80 Attikum04 2.95 0.0011 79SWI6_YPD _SWC2_(VPS72)Krogan04 2.95 0.0011 145SWI6_YPD WT_F182V Chitikila_02 2.95 0.0011 125CIN5_YPD gcn5D_taf1-ts2Durant06 2.95 0.0011 134CIN5_YPD hpa2D_taf1-ts2Durant06 2.95 0.0011 112

DAL81_RAPA WT_V161R_L Chitikila_02 -2.95 0.0011 94GCN4_RAPA hat2_vs._YPH250Rosaleny05 -2.95 0.0011 154GCN4_RAPA swr1_del Mizuguch04 2.95 0.0011 159CIN5_H2O2Hi Hda1_del Bernstein02 2.95 0.0011 80HSF1_H2O2Hi WT_V161R_K Chitikila_02 -2.95 0.0011 113HSF1_H2O2Hi taf1-ts2_gcn5 Huisinga04 2.95 0.0011 116MSN2_H2O2Hihat2_vs._hat1Rosaleny05 -2.95 0.0011 76MSN4_H2O2HiDpho23 Keogh05 2.95 0.0011 70NRG1_H2O2Hirpd3_H3dN_v_H3dNSabet04 2.95 0.0011 120SKN7_H2O2Hi taf1-ts2 Durant06 2.95 0.0011 97SKN7_H2O2HiDT_V161E Chitikila_02 -2.95 0.0011 88UME6_H2O2HiDpho23 Keogh05 2.95 0.0011 100YAP6_H2O2Hi YNG2 Mnaimneh_04 2.95 0.0011 79YAP6_H2O2Hi Rpd3_del Bernstein02 -2.95 0.0011 79YAP6_H2O2Hi rsc30_null Angus-Hill_01 -2.95 0.0011 77AFT2_H2O2Lo H4_2-26 Sabet04 2.95 0.0011 92HSF1_H2O2Loelp3D_taf1-ts2Durant06 2.95 0.0011 85HSF1_H2O2Loswr1_del Mizuguch04 2.95 0.0011 101MBP1_H2O2LoWT_TAF1_SPT3Huisinga04 -2.95 0.0011 53PUT3_H2O2Lo rpd3_H3dN_v_H3dNSabet04 2.95 0.0011 85PUT3_H2O2Lo gcn5 Huisinga04 2.95 0.0011 85RCS1_H2O2LoTUP1_haploid Hughes00 -2.95 0.0011 250RCS1_H2O2Lohht2_K4914182327GMartin04 2.95 0.0011 227RIM101_H2O2Lohht2_K27G Martin04 -2.95 0.0011 31YAP6_H2O2Lo UBP8 Ingvarsdottir05 2.95 0.0011 55SOK2_BUT14 sir2 Meneghini03 2.95 0.0011 70GCN4_YPD taf1-ts2_GCN5Huisinga04 2.95 0.0011 70NDD1_YPD WT_V161R_L Chitikila_02 -2.95 0.0011 82PHD1_YPD hht2_K4914182327GMartin04 2.92 0.0012 47ROX1_YPD TUP1_haploid Hughes00 2.92 0.0012 67SKN7_YPD rpd3_H3dN_v_H3dNSabet04 2.92 0.0012 62STE12_YPD ino80_del Mizuguch04 -2.92 0.0012 54SWI6_YPD hht2_K27G Martin04 2.92 0.0012 127YAP6_YPD HDA1 Hughes00 2.92 0.0012 91YAP6_YPD WT_V71R Chitikila_02 2.92 0.0012 85CIN5_YPD YNG2 Mnaimneh_04 2.92 0.0012 150CIN5_YPD DT_N69S Chitikila_02 -2.92 0.0012 136DAL81_RAPA WT_N69R Chitikila_02 -2.92 0.0012 90DAL81_RAPA Dsin3 Keogh05 2.92 0.0012 84GLN3_RAPA esa1-414_taf1-ts2Durant06 2.92 0.0012 62HSF1_H2O2Hi spt10 Eriksson05 -2.92 0.0012 123HSF1_H2O2Hi taf1-ts2 Durant06 2.92 0.0012 122MBP1_H2O2Hihht2_K4914182327GMartin04 2.92 0.0012 113NRG1_H2O2Hiino80_del Mizuguch04 2.92 0.0012 126YAP6_H2O2Hi WT_N69R Chitikila_02 2.92 0.0012 73AFT2_H2O2Lo gcn5 Huisinga04 2.92 0.0012 95MBP1_H2O2Lohht2K9131823GMartin04 2.92 0.0012 47PUT3_H2O2Lo RPD3_haploid Hughes00 2.92 0.0012 88PUT3_H2O2Lo sir2 Meneghini03 2.92 0.0012 86RCS1_H2O2Loswr1 Meneghini03 2.92 0.0012 211RIM101_H2O2LoDM_vs._YPH250Rosaleny05 2.92 0.0012 46RPN4_H2O2LoMOT1-14 Dasgupta02 -2.92 0.0012 100RPN4_H2O2Lohht2_K4G Martin04 2.92 0.0012 87

DIG1_Alpha sap30_del Bernstein_00_affydeletions-2.92 0.0012 53MCM1_Alpha ARP4 Mnaimneh_04 2.92 0.0012 105ASH1_BUT14 elp3D_taf1-ts2Durant06 2.92 0.0012 44ASH1_BUT14 YNG2 Krogan04 2.92 0.0012 46PHD1_BUT90 sas3D_taf1-ts2Durant06 2.92 0.0012 95STE12_BUT90 ARD1 Hughes00 -2.92 0.0012 78FKH2_YPD EPL1 Mnaimneh_04 2.92 0.0012 121GCN4_YPD UBP8 Ingvarsdottir05 -2.92 0.0012 67HAP1_YPD SSN6_haploid Hughes00 2.92 0.0012 140HAP1_YPD taf1-ts2_gcn5_KQLHuisinga04 2.92 0.0012 116MBP1_YPD ARD1 Hughes00 -2.92 0.0012 129NDD1_YPD ISW1_ISW2 Hughes00 2.92 0.0012 84NRG1_YPD rpd3_H4KQ_v_H4KQSabet04 -2.92 0.0012 60ABF1_YPD WT_N69R Chitikila_02 2.88 0.0013 238SUT1_YPD ino80_del Mizuguch04 2.88 0.0013 69SUT1_YPD YNG2 Krogan04 2.88 0.0013 65SWI5_YPD spt10_del Xu05 2.88 0.0013 99SWI5_YPD taf1-ts2_GCN5Huisinga04 2.88 0.0013 93SWI6_YPD SWC6_(VPS71)Krogan04 2.88 0.0013 138UME6_YPD esa1-414_taf1-ts2Durant06 2.88 0.0013 117CIN5_YPD ubp10sir4 Orlandi04 -2.88 0.0013 95CIN5_YPD Drco1 Keogh05 2.88 0.0013 139GCN4_SM WT_V71R Chitikila_02 -2.88 0.0013 172DAL81_RAPA WT_V71R Chitikila_02 -2.88 0.0013 89MSN2_H2O2HiHST3 Hughes00 2.88 0.0013 76NRG1_H2O2Hitaf1-ts2 Durant06 2.88 0.0013 122NRG1_H2O2Hiisw2_rpd3 Fazzio01 -2.88 0.0013 123RCS1_H2O2Hi swi1_rich_medium_experimentSudarsanam00 2.88 0.0013 52YAP7_H2O2Hi rpd3 Fazzio01 -2.88 0.0013 137YAP7_H2O2Hi rpd3_del Sabet04 2.88 0.0013 138PUT3_H2O2Lo taf1-ts2_spt3 Huisinga04 2.88 0.0013 84RIM101_H2O2LoDT_V161R_K Chitikila_02 2.88 0.0013 52XBP1_H2O2Lo Drxt1 Keogh05 -2.88 0.0013 66YAP6_H2O2Lo Set1_del Bernstein02 2.88 0.0013 57ASH1_BUT14 spt3 Huisinga04 -2.88 0.0013 48DIG1_BUT14 sir2 Meneghini03 -2.88 0.0013 63SOK2_BUT14 rpd3_c.i. Fazzio01 -2.88 0.0013 71SOK2_BUT14 isw2_rpd3 Fazzio01 -2.88 0.0013 71SOK2_BUT14 WT_V161E Chitikila_02 -2.88 0.0013 66HAP4_YPD spt10 Eriksson05 -2.88 0.0013 63NRG1_YPD hht2_K27G Martin04 -2.88 0.0013 31ABF1_YPD H4_2-26 Sabet04 -2.85 0.0014 261ABF1_YPD taf1-ts2_25C Huisinga04 2.85 0.0014 250STE12_YPD Dume1 Keogh05 -2.85 0.0014 52SUM1_YPD SIN3 Hughes00 -2.85 0.0014 58SUT1_YPD ino80 Attikum04 2.85 0.0014 50SWI6_YPD hpa2D Durant06 -2.85 0.0014 123CIN5_YPD HIR2 Hughes00 2.85 0.0014 150CIN5_H2O2Hi hat1D Durant06 -2.85 0.0014 48MBP1_H2O2HiSAP30 Hughes00 2.85 0.0014 130MBP1_H2O2Higcn5_KQL Huisinga04 -2.85 0.0014 110MSN2_H2O2Hirpd3_H4KQ_v_H4KQSabet04 -2.85 0.0014 74SKN7_H2O2Hi rsc30_null Angus-Hill_01 -2.85 0.0014 98

RPN4_H2O2Loume6_del Bernstein_00_affydeletions2.85 0.0014 98YAP7_H2O2Lo ino80 Attikum04 2.85 0.0014 126FKH1_YPD ISW2 Hughes00 -2.85 0.0014 140STE12_BUT14 Dsap30 Keogh05 -2.85 0.0014 124PHD1_BUT90 DT_V161E Chitikila_02 -2.85 0.0014 100STE12_BUT90 YNG2 Krogan04 2.85 0.0014 75MGA1_YPD Drpd3 Keogh05 -2.85 0.0014 58NDD1_YPD delta_ssd1 Kaeberlein04 2.85 0.0014 85NRG1_YPD WT_Null_K Chitikila_02 -2.85 0.0014 67ABF1_YPD SIR4 Hughes00 2.82 0.0015 263SKN7_YPD sas3D_taf1-ts2Durant06 2.82 0.0015 62SWI4_YPD WT_WT Chitikila_02 -2.82 0.0015 153GCR2_SM spt10_del Xu05 -2.82 0.0015 53DAL81_RAPA SIR1 Hughes00 2.82 0.0015 94DAL81_RAPA MOT1-14 Dasgupta02 2.82 0.0015 92DAL81_RAPA DT_V161E Chitikila_02 -2.82 0.0015 92FKH2_H2O2Hi SWC6_(VPS71)Krogan04 2.82 0.0015 94FKH2_H2O2Hi EAF7 Krogan04 2.82 0.0015 98YAP6_H2O2Hi sin3 Fazzio01 -2.82 0.0015 73AFT2_H2O2Lo Drco1 Keogh05 2.82 0.0015 88HSF1_H2O2LoH4_2-26 Sabet04 2.82 0.0015 97RPN4_H2O2LoMED2_haploid Hughes00 2.82 0.0015 98RPN4_H2O2Losas3D Durant06 2.82 0.0015 83SKN7_H2O2LoSPT8 Ingvarsdottir05 -2.82 0.0015 168SKN7_H2O2LoHST3 Hughes00 2.82 0.0015 184SKN7_H2O2Loisw2_sin3 Fazzio01 -2.82 0.0015 181XBP1_H2O2Lo rpd3 Fazzio01 -2.82 0.0015 65MCM1_Alpha htz1_hmr Meneghini03 2.82 0.0015 106ASH1_BUT14 WT_V71E Chitikila_02 -2.82 0.0015 43ASH1_BUT14 hht2_K49141823GMartin04 2.82 0.0015 39FKH2_YPD SAP30 Hughes00 2.82 0.0015 119ACE2_YPD YNG2 Krogan04 2.82 0.0015 76GCN4_YPD hpa2D_taf1-ts2Durant06 2.82 0.0015 62GCN4_YPD Drpd3 Keogh05 2.82 0.0015 68MBP1_YPD DT_V161R_L Chitikila_02 -2.82 0.0015 126NDD1_YPD YNG2 Krogan04 2.82 0.0015 81OAF1_YPD Rpd3_del Bernstein02 2.82 0.0015 59ABF1_YPD UBP8 Ingvarsdottir05 -2.79 0.0016 242RLM1_YPD hda1_del Bernstein_00_affydeletions2.79 0.0016 47STE12_YPD Ddep1 Keogh05 -2.79 0.0016 49STE12_YPD Dsin3 Keogh05 -2.79 0.0016 41YAP6_YPD DT_V161E Chitikila_02 -2.79 0.0016 84CIN5_YPD gcn5 Huisinga04 2.79 0.0016 141GCN4_SM RPD3_haploid Hughes00 2.79 0.0016 188GCR2_SM hos3_del Bernstein_00_affydeletions2.79 0.0016 51DAL81_RAPA WT_V71E Chitikila_02 -2.79 0.0016 80AFT2_H2O2Hi WT_TAF1_SPT3Huisinga04 2.79 0.0016 57HSF1_H2O2Hi taf1-ts2_GCN5Huisinga04 2.79 0.0016 114NRG1_H2O2Hitaf1-ts2_gcn5_KQLHuisinga04 2.79 0.0016 110RCS1_H2O2Hi htz1_del Mizuguch04 2.79 0.0016 52MBP1_H2O2Lorpd3 Fazzio01 2.79 0.0016 54MBP1_H2O2Losin3 Fazzio01 2.79 0.0016 54RCS1_H2O2LoEAF5 Krogan04 -2.79 0.0016 238

XBP1_H2O2Lo ARD1 Hughes00 -2.79 0.0016 67SOK2_BUT14 taf1-ts2_spt3 Huisinga04 -2.79 0.0016 67PHD1_BUT90 swi1_minimal_medium_experimentSudarsanam00 2.79 0.0016 106PHD1_BUT90 gcn5D_taf1-ts2Durant06 2.79 0.0016 95STE12_BUT90 ZDS1 Hughes00 2.79 0.0016 78FKH2_YPD YNG2 Mnaimneh_04 2.79 0.0016 121FKH2_YPD isw2_c.i. Fazzio01 2.79 0.0016 119GCN4_YPD DM_vs._YPH250Rosaleny05 2.79 0.0016 70MBP1_YPD WT_V71E Chitikila_02 -2.79 0.0016 113MBP1_YPD spt3 Huisinga04 -2.79 0.0016 122MGA1_YPD rpd3 Fazzio01 -2.79 0.0016 60NDD1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -2.79 0.0016 73NRG1_YPD Dsap30 Keogh05 -2.79 0.0016 71ABF1_YPD MOT1-14 Dasgupta02 -2.76 0.0017 262ABF1_YPD taf1-ts2 Durant06 2.76 0.0017 263PHD1_YPD isw2_rpd3 Fazzio01 -2.76 0.0017 66PHD1_YPD sap30_del Bernstein_00_affydeletions-2.76 0.0017 57PHD1_YPD Drxt2 Keogh05 -2.76 0.0017 61SKN7_YPD taf1-ts2_SPT3 Huisinga04 2.76 0.0017 65SUM1_YPD Drpd3 Keogh05 -2.76 0.0017 52UME6_YPD taf1-ts2_GCN5Huisinga04 2.76 0.0017 117GCN4_SM DT_V71R Chitikila_02 2.76 0.0017 180GCN4_RAPA HTZ1 Krogan04 2.76 0.0017 145HSF1_H2O2Hi SPT3 Ingvarsdottir05 2.76 0.0017 112MSN2_H2O2Hitaf1-ts2_spt3_E240KHuisinga04 2.76 0.0017 68NRG1_H2O2HiIOC4 Hughes00 -2.76 0.0017 125YAP6_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 -2.76 0.0017 73YAP6_H2O2Hi hda1_del Bernstein_00_affydeletions2.76 0.0017 68AFT2_H2O2Lo WT_TAF1_GCN5Huisinga04 2.76 0.0017 97RCS1_H2O2LoUBP8 Hughes00 -2.76 0.0017 256RIM101_H2O2LoYNG2 Mnaimneh_04 2.76 0.0017 54RIM101_H2O2LoMOT1-14 Dasgupta02 2.76 0.0017 54SKN7_H2O2LoUBP8 Hughes00 2.76 0.0017 183XBP1_H2O2Lo ubp10sir4 Orlandi04 -2.76 0.0017 31YAP7_H2O2Lo esa1-414_taf1-ts2Durant06 2.76 0.0017 138MCM1_Alpha hht2K9131823GMartin04 2.76 0.0017 90DIG1_BUT14 sin3_del Bernstein_00_affydeletions-2.76 0.0017 60ACE2_YPD taf1-ts2_GCN5Huisinga04 2.76 0.0017 74GCN4_YPD _SWC2_(VPS72)Krogan04 2.76 0.0017 66HAP1_YPD swi1_minimal_medium_experimentSudarsanam00 2.76 0.0017 141MBP1_YPD Drxt1 Keogh05 -2.76 0.0017 129NRG1_YPD UBP8 Ingvarsdottir05 2.76 0.0017 65NRG1_YPD H4_2-26 Sabet04 2.76 0.0017 60PHD1_YPD taf1-ts2_SPT3 Huisinga04 -2.74 0.0018 66SKN7_YPD SWD2 Mnaimneh_04 2.74 0.0018 67STE12_YPD taf1-ts2_SPT3 Huisinga04 2.74 0.0018 48SUM1_YPD HIR2 Hughes00 2.74 0.0018 57SWI4_YPD EAF7 Krogan04 2.74 0.0018 144UME6_YPD Drxt2 Keogh05 2.74 0.0018 119AFT2_H2O2Hi SGF11 Ingvarsdottir05 2.74 0.0018 52FKH2_H2O2Hi htz1 Meneghini03 2.74 0.0018 105MSN2_H2O2HiDM_vs._YPH250Rosaleny05 2.74 0.0018 75SKN7_H2O2HiRSC8 Mnaimneh_04 2.74 0.0018 98

AFT2_H2O2Lo 0.1%_MMS Attikum04 2.74 0.0018 73MBP1_H2O2Lorpd3_c.i. Fazzio01 2.74 0.0018 54YAP6_H2O2Lo taf1-ts2 Durant06 -2.74 0.0018 57DIG1_Alpha taf1-ts2_gcn5 Huisinga04 2.74 0.0018 54STE12_BUT14 taf1-ts2_GCN5Huisinga04 2.74 0.0018 121ACE2_YPD htz1_sir2 Meneghini03 2.74 0.0018 80GCN4_YPD taf1-ts2_SPT3 Huisinga04 2.74 0.0018 71HAP4_YPD PCH1 Hughes00 2.74 0.0018 63NDD1_YPD WT_F182V Chitikila_02 2.74 0.0018 78PHD1_YPD hht2_K914182327GMartin04 2.72 0.0019 45STE12_YPD SPT8 Ingvarsdottir05 -2.72 0.0019 51STE12_YPD gcn5D Durant06 -2.72 0.0019 43SWI4_YPD isw2_c.i. Fazzio01 2.72 0.0019 152GCN4_RAPA TUP1_haploid Hughes00 2.72 0.0019 160GCN4_RAPA spt3 Huisinga04 -2.72 0.0019 157CIN5_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 -2.72 0.0019 78MBP1_H2O2Hi spt3 Huisinga04 -2.72 0.0019 125AFT2_H2O2Lo Set1_del Bernstein02 2.72 0.0019 97CIN5_H2O2Lo WT_V71E Chitikila_02 -2.72 0.0019 110CIN5_H2O2Lo DT_N69S Chitikila_02 -2.72 0.0019 117HSF1_H2O2Lospt10 Eriksson05 -2.72 0.0019 101RPN4_H2O2Logcn5_KQL Huisinga04 2.72 0.0019 91DIG1_Alpha htz1_sir2 Meneghini03 -2.72 0.0019 59STE12_Alpha 0.1%_MMS Attikum04 -2.72 0.0019 86DIG1_BUT14 htz1_del Mizuguch04 2.72 0.0019 62GCN4_YPD DT_N69S Chitikila_02 2.72 0.0019 74GCN4_YPD Dume1 Keogh05 2.72 0.0019 68SKN7_YPD ubp10sir4 Orlandi04 -2.69 0.002 43STE12_YPD sin3_del Bernstein_00_affydeletions-2.69 0.002 49SUM1_YPD UBP8 Hughes00 2.69 0.002 58DAL81_RAPA Dpho23 Keogh05 2.69 0.002 94DAL82_RAPA TUP1_haploid Hughes00 2.69 0.002 55DAL82_RAPA spt3_E240K Huisinga04 -2.69 0.002 52FKH2_H2O2Hi taf1-ts2_25C Huisinga04 2.69 0.002 91XBP1_H2O2Lo sap30_del Bernstein_00_affydeletions-2.69 0.002 53YAP6_H2O2Lo sin3_del Bernstein_00_affydeletions-2.69 0.002 50STE12_Alpha RPD3_haploid Hughes00 -2.69 0.002 114STE12_Alpha DT_WT Chitikila_02 -2.69 0.002 110FKH1_YPD Hda1_del Bernstein02 -2.69 0.002 140SOK2_BUT14 sin3_del Bernstein_00_affydeletions-2.69 0.002 60HAP1_YPD hht2K9131823GMartin04 -2.69 0.002 122NRG1_YPD spt3_E240K Huisinga04 -2.69 0.002 64OAF1_YPD Dsin3 Keogh05 2.69 0.002 50PHD1_YPD hos2_del Bernstein_00_affydeletions-2.67 0.0021 57RLM1_YPD sas3D_taf1-ts2Durant06 2.67 0.0021 49SWI4_YPD swi1_minimal_medium_experimentSudarsanam00 -2.67 0.0021 155GCR2_SM VID21 Krogan04 2.67 0.0021 49DAL81_RAPA hat1D_taf1-ts2Durant06 2.67 0.0021 71DAL81_RAPA rpd3_c.i. Fazzio01 -2.67 0.0021 90DAL81_RAPA rpd3_H3dN_v_H3dNSabet04 2.67 0.0021 94MSN4_H2O2HiHIR2 Hughes00 2.67 0.0021 69PUT3_H2O2Lo arp8_+_0.1%_MMS_vs._arp8Attikum04 2.67 0.0021 69PUT3_H2O2Lo rsc3-2 Angus-Hill_01 2.67 0.0021 87

RIM101_H2O2Lohda1_del Bernstein_00_affydeletions2.67 0.0021 40RPN4_H2O2Lohtz1 Meneghini03 2.67 0.0021 98RPN4_H2O2LoDT_V161R_K Chitikila_02 -2.67 0.0021 98SKN7_H2O2LoWT_Null_K Chitikila_02 -2.67 0.0021 176DIG1_Alpha taf1-ts2_25C Huisinga04 2.67 0.0021 56STE12_Alpha spt3 Huisinga04 -2.67 0.0021 107SOK2_BUT14 snf2_rich_medium_experimentSudarsanam00 2.67 0.0021 71PHD1_BUT90 rpd3_c.i. Fazzio01 -2.67 0.0021 103STE12_BUT90 _SWC2_(VPS72)Krogan04 2.67 0.0021 73ACE2_YPD gcn5D Durant06 2.67 0.0021 68NDD1_YPD sin3 Fazzio01 2.67 0.0021 80NRG1_YPD DT_WT Chitikila_02 -2.67 0.0021 64SWI4_YPD htz1_sir2 Meneghini03 2.65 0.0022 153SWI6_YPD taf1-ts2 Durant06 2.65 0.0022 151SWI6_YPD taf1-ts2_gcn5_KQLHuisinga04 -2.65 0.0022 123UME6_YPD MOT1-42 Dasgupta02 2.65 0.0022 131DAL81_RAPA SIR4 Hughes00 2.65 0.0022 95GLN3_RAPA ubp10 Orlandi04 -2.65 0.0022 49MSN2_H2O2Hispt10_del Xu05 2.65 0.0022 76RCS1_H2O2Hi 0.1%_MMS Attikum04 2.65 0.0022 36REB1_H2O2Hi htz1_del Mizuguch04 -2.65 0.0022 59CIN5_H2O2Lo esa1-414_taf1-ts2Durant06 2.65 0.0022 107RCS1_H2O2Logcn5D Durant06 2.65 0.0022 217XBP1_H2O2Lo ISW1 Hughes00 2.65 0.0022 67MCM1_Alpha 0.1%_MMS Attikum04 -2.65 0.0022 90FKH1_YPD isw2_rpd3 Fazzio01 2.65 0.0022 139PHD1_BUT90 spt10_del Xu05 -2.65 0.0022 104ACE2_YPD isw2_rpd3_vs._rpd3Fazzio01 -2.65 0.0022 72MBP1_YPD SWC6_(VPS71)Krogan04 2.65 0.0022 115NRG1_YPD WT Durant06 -2.65 0.0022 67PHD1_YPD spt3_E240K Huisinga04 -2.63 0.0023 60SWI6_YPD sap30_del Bernstein_00_affydeletions2.63 0.0023 142CIN5_YPD sir4 Orlandi04 -2.63 0.0023 90CIN5_YPD hda1_del Bernstein_00_affydeletions2.63 0.0023 138DAL81_RAPA isw2_c.i._rpd3_c.i.Fazzio01 -2.63 0.0023 91GCN4_RAPA sir2 Meneghini03 2.63 0.0023 158FKH2_H2O2Hi _SWC2_(VPS72)Krogan04 2.63 0.0023 102MBP1_H2O2Hi sas3D Durant06 -2.63 0.0023 107MSN2_H2O2HiDrpd3 Keogh05 2.63 0.0023 71MSN4_H2O2HiEAF5 Krogan04 2.63 0.0023 61NRG1_H2O2Hihtz1_sir2 Meneghini03 2.63 0.0023 123REB1_H2O2Hi WT_N69R Chitikila_02 2.63 0.0023 55RPN4_H2O2Losir4 Orlandi04 -2.63 0.0023 80MCM1_Alpha isw2_rpd3_vs._rpd3Fazzio01 2.63 0.0023 104STE12_Alpha gcn5D Durant06 -2.63 0.0023 94SOK2_BUT14 Deaf3 Keogh05 2.63 0.0023 65PHD1_BUT90 UBP8 Hughes00 2.63 0.0023 106PHD1_BUT90 Rpd3_del Bernstein02 -2.63 0.0023 105GCN4_YPD HTZ1 Krogan04 2.63 0.0023 66NDD1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -2.63 0.0023 74NDD1_YPD SSD1-V Kaeberlein04 2.63 0.0023 84RLM1_YPD sir4 Orlandi04 -2.61 0.0024 37SUT1_YPD isw2 Fazzio01 -2.61 0.0024 68

SUT1_YPD hda1_del Bernstein_00_affydeletions2.61 0.0024 65SUT1_YPD Set1_del Bernstein02 2.61 0.0024 69SWI6_YPD rpd3_c.i. Fazzio01 2.61 0.0024 148CIN5_YPD sir2 Meneghini03 2.61 0.0024 147DAL82_SM HDA1 Hughes00 2.61 0.0024 55GLN3_RAPA WT_N69S Chitikila_02 -2.61 0.0024 64MSN4_H2O2HiMOT1-42 Dasgupta02 2.61 0.0024 70UME6_H2O2HiYNG2 Mnaimneh_04 2.61 0.0024 101UME6_H2O2Hitaf1-ts2_gcn5 Huisinga04 2.61 0.0024 98YAP7_H2O2Lo ino80_del Mizuguch04 2.61 0.0024 152DIG1_Alpha gcn5D Durant06 -2.61 0.0024 48FKH1_YPD isw2_c.i. Fazzio01 2.61 0.0024 139SOK2_BUT14 IES6 Hughes00 2.61 0.0024 72HAP1_YPD gcn5D_taf1-ts2Durant06 2.61 0.0024 134HAP4_YPD Dume1 Keogh05 -2.61 0.0024 63NDD1_YPD Dsds3 Keogh05 2.61 0.0024 81SUT1_YPD DT_N69R Chitikila_02 2.6 0.0025 65SWI6_YPD sir4 Orlandi04 -2.6 0.0025 106UME6_YPD HTZ1 Krogan04 2.6 0.0025 121YAP6_YPD isw2_sin3_vs._sin3Fazzio01 -2.6 0.0025 88YAP6_YPD hht2_K27G Martin04 -2.6 0.0025 61CIN5_YPD sin3 Fazzio01 -2.6 0.0025 148CIN5_YPD DT_Null Chitikila_02 2.6 0.0025 147GCN4_SM spt3_E240K Huisinga04 2.6 0.0025 166GLN3_RAPA taf1-ts2_gcn5_KQLHuisinga04 2.6 0.0025 65FKH2_H2O2Hi WT_V161E Chitikila_02 -2.6 0.0025 92MSN4_H2O2HiYNG2 Mnaimneh_04 2.6 0.0025 70NRG1_H2O2HiBUR6 Geisberg_01 2.6 0.0025 113SKN7_H2O2HiSWC6_(VPS71)Krogan04 2.6 0.0025 87SKN7_H2O2HiWT_TAF1_GCN5Huisinga04 -2.6 0.0025 97YAP7_H2O2Hi PCH1 Hughes00 2.6 0.0025 139RIM101_H2O2LoWT Durant06 -2.6 0.0025 51XBP1_H2O2Lo DT_V161R_K Chitikila_02 2.6 0.0025 67HAP4_YPD spt3_E240K Huisinga04 2.6 0.0025 62RLM1_YPD esa1-414_taf1-ts2Durant06 2.58 0.0026 49SKN7_YPD TAF2 Mnaimneh_04 2.58 0.0026 67YAP6_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -2.58 0.0026 63DAL82_RAPA Dpho23 Keogh05 -2.58 0.0026 55HSF1_H2O2Hi DT_V161R_L Chitikila_02 2.58 0.0026 119YAP7_H2O2Hi esa1-414_taf1-ts2Durant06 2.58 0.0026 130PUT3_H2O2Lo rpd3_c.i. Fazzio01 -2.58 0.0026 86RCS1_H2O2Lohda1_del Bernstein_00_affydeletions2.58 0.0026 248RPN4_H2O2Loesa1-414_taf1-ts2Durant06 2.58 0.0026 92YAP7_H2O2Lo taf1-ts2_gcn5_KQLHuisinga04 2.58 0.0026 133DIG1_Alpha taf1-ts2_GCN5Huisinga04 2.58 0.0026 56STE12_BUT14 swr1_del Mizuguch04 2.58 0.0026 128FKH2_YPD WT_V161E Chitikila_02 -2.58 0.0026 110MBP1_YPD rpd3_c.i. Fazzio01 2.58 0.0026 123NDD1_YPD swr1 Meneghini03 2.58 0.0026 71RLM1_YPD spt3 Huisinga04 -2.56 0.0027 54SUT1_YPD isw2_sin3 Fazzio01 -2.56 0.0027 69SWI6_YPD elp3D_taf1-ts2Durant06 2.56 0.0027 130GCN4_SM gcn5D_taf1-ts2Durant06 2.56 0.0027 174

GCR2_SM IES6 Hughes00 -2.56 0.0027 54GCR2_SM DT_V161R_L Chitikila_02 -2.56 0.0027 53RTG3_RAPA taf1-ts2_GCN5Huisinga04 2.56 0.0027 47CIN5_H2O2Hi arp8 Attikum04 -2.56 0.0027 58CIN5_H2O2Hi MOT1-42 Dasgupta02 2.56 0.0027 80HSF1_H2O2Hi taf1-ts2_spt3 Huisinga04 2.56 0.0027 119NRG1_H2O2HiMOT1-14 Dasgupta02 2.56 0.0027 124NRG1_H2O2Hihht2_K914182327GMartin04 -2.56 0.0027 81SKN7_H2O2Hi hat1D_taf1-ts2Durant06 2.56 0.0027 81YAP6_H2O2Hi Drxt2 Keogh05 -2.56 0.0027 75MBP1_H2O2Logcn5 Huisinga04 -2.56 0.0027 54SKN7_H2O2LoEAF7 Krogan04 2.56 0.0027 169SKN7_H2O2Loisw2_sin3_vs._sin3Fazzio01 -2.56 0.0027 181ASH1_BUT14 Ddep1 Keogh05 2.56 0.0027 49SOK2_BUT14 ISW1_ISW2 Hughes00 2.56 0.0027 72SOK2_BUT14 gcn5D_taf1-ts2Durant06 2.56 0.0027 61HAP4_YPD DT_V71E Chitikila_02 -2.56 0.0027 64MBP1_YPD swr1 Meneghini03 2.56 0.0027 112MGA1_YPD DM_vs._YPH250Rosaleny05 -2.56 0.0027 57NRG1_YPD hat1D_taf1-ts2Durant06 -2.56 0.0027 53ABF1_YPD SPT3 Ingvarsdottir05 2.55 0.0028 234STE12_YPD arp8 Attikum04 -2.55 0.0028 41SWI4_YPD htz1 Meneghini03 2.55 0.0028 153GCN4_SM swi1_minimal_medium_experimentSudarsanam00 -2.55 0.0028 189GCN4_SM Ddep1 Keogh05 2.55 0.0028 176DAL81_RAPA gcn5D_taf1-ts2Durant06 2.55 0.0028 91DAL82_RAPA isw2_rpd3 Fazzio01 -2.55 0.0028 54HSF1_H2O2Hi hat1D_taf1-ts2Durant06 2.55 0.0028 108MSN4_H2O2Hihat2_vs._hat1Rosaleny05 -2.55 0.0028 67MSN4_H2O2HiDrpd3 Keogh05 2.55 0.0028 65YAP7_H2O2Lo isw2_c.i._rpd3_c.i.Fazzio01 -2.55 0.0028 148MBP1_YPD DT_V161R_K Chitikila_02 -2.55 0.0028 126MBP1_YPD WT_WT Chitikila_02 -2.55 0.0028 123NDD1_YPD isw2_c.i._rpd3_c.i.Fazzio01 2.55 0.0028 80NRG1_YPD htz1_hmr Meneghini03 -2.55 0.0028 71NRG1_YPD WT_V71R Chitikila_02 2.55 0.0028 66PHD1_YPD swr1 Meneghini03 -2.53 0.0029 55STE12_YPD isw2_sin3_vs._sin3Fazzio01 -2.53 0.0029 53SUM1_YPD Dsds3 Keogh05 -2.53 0.0029 55GCN4_SM TUP1_haploid Hughes00 2.53 0.0029 188DAL82_RAPA Drxt2 Keogh05 -2.53 0.0029 54MSN2_H2O2HiMOT1-14 Dasgupta02 2.53 0.0029 78UME6_H2O2HiMOT1-42 Dasgupta02 2.53 0.0029 101YAP7_H2O2Lo isw2_rpd3 Fazzio01 -2.53 0.0029 148STE12_Alpha Drxt1 Keogh05 -2.53 0.0029 113HAP1_YPD ISW1 Hughes00 2.53 0.0029 141MGA1_YPD ARP4 Mnaimneh_04 -2.53 0.0029 63STE12_YPD rpd3 Fazzio01 -2.52 0.003 53SUM1_YPD DT_V161E Chitikila_02 -2.52 0.003 48YAP6_YPD elp3D_taf1-ts2Durant06 -2.52 0.003 62YAP6_YPD htz1 Meneghini03 -2.52 0.003 89CIN5_YPD MOT1-14 Dasgupta02 2.52 0.003 149DAL82_RAPA rpd3_H3dN_v_H3dNSabet04 -2.52 0.003 53

UME6_H2O2HiDT_V71R Chitikila_02 2.52 0.003 93HSF1_H2O2Lo ino80 Attikum04 -2.52 0.003 86XBP1_H2O2Lo swi1_minimal_medium_experimentSudarsanam00 2.52 0.003 68FKH1_YPD taf1-ts2_gcn5_KQLHuisinga04 -2.52 0.003 123ACE2_YPD taf1-ts2 Durant06 2.52 0.003 78HAP4_YPD UBP8 Hughes00 -2.52 0.003 66NRG1_YPD elp3D_taf1-ts2Durant06 -2.52 0.003 44NRG1_YPD hht2K9131823GMartin04 2.52 0.003 34RLM1_YPD SSN6_haploid Hughes00 2.5 0.0031 53SKN7_YPD WT_V71R Chitikila_02 -2.5 0.0031 64STE12_YPD isw2_c.i. Fazzio01 2.5 0.0031 54STE12_YPD isw2_c.i._rpd3_c.i.Fazzio01 -2.5 0.0031 54DAL81_RAPA swi1_rich_medium_experimentSudarsanam00 2.5 0.0031 95GCN4_RAPA DT_WT Chitikila_02 -2.5 0.0031 156GLN3_RAPA H4_2-26 Sabet04 2.5 0.0031 65MSN4_H2O2HiWT_V161R_L Chitikila_02 -2.5 0.0031 70NRG1_H2O2HiSIR3 Hughes00 2.5 0.0031 126RCS1_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 2.5 0.0031 47CIN5_H2O2Lo sin3_del Bernstein_00_affydeletions-2.5 0.0031 112MBP1_H2O2LoDM_vs._YPH250Rosaleny05 2.5 0.0031 53MBP1_H2O2LoHDA1 Hughes00 -2.5 0.0031 58PUT3_H2O2Lo ARD1 Hughes00 2.5 0.0031 88RCS1_H2O2Lohht2_K4G Martin04 2.5 0.0031 218SKN7_H2O2LoSIR2 Hughes00 -2.5 0.0031 184SKN7_H2O2LoISW1 Hughes00 2.5 0.0031 184XBP1_H2O2Lo WT_V71R Chitikila_02 2.5 0.0031 59SOK2_BUT14 H4_2-26 Sabet04 2.5 0.0031 65ACE2_YPD htz1_del Mizuguch04 2.5 0.0031 80HAP1_YPD UBP8 Hughes00 2.5 0.0031 141MGA1_YPD taf1-ts2 Durant06 -2.5 0.0031 60SKN7_YPD taf1-ts2_gcn5 Huisinga04 2.49 0.0032 65SUT1_YPD taf1-ts2_gcn5_KQLHuisinga04 2.49 0.0032 63SWI6_YPD HTZ1 Krogan04 2.49 0.0032 140CIN5_YPD elp3D_taf1-ts2Durant06 2.49 0.0032 108CIN5_YPD gcn5D Durant06 2.49 0.0032 123DAL82_RAPA Dsap30 Keogh05 -2.49 0.0032 54RTG3_RAPA HST3 Hughes00 2.49 0.0032 52HSF1_H2O2Hi WT_N69R Chitikila_02 -2.49 0.0032 115HSF1_H2O2LoBUR6 Geisberg_01 2.49 0.0032 94PUT3_H2O2Lo hmr Meneghini03 2.49 0.0032 84RCS1_H2O2LoDT_Null Chitikila_02 2.49 0.0032 240RIM101_H2O2Lohos2_del Bernstein_00_affydeletions-2.49 0.0032 39RIM101_H2O2Lospt3_E240K Huisinga04 -2.49 0.0032 48RPN4_H2O2Losap30_del Bernstein_00_affydeletions2.49 0.0032 98YAP7_H2O2Lo H4KQ Sabet04 2.49 0.0032 147DIG1_Alpha sir2 Meneghini03 -2.49 0.0032 59STE12_Alpha isw2 Fazzio01 -2.49 0.0032 112DIG1_BUT14 ZDS1 Hughes00 2.49 0.0032 63SOK2_BUT14 YNG2 Krogan04 2.49 0.0032 70SWI4_YPD spt3_E240K Huisinga04 -2.48 0.0033 132SWI5_YPD rpd3_H4KQ_v_H4KQSabet04 -2.48 0.0033 93CIN5_YPD YNG2 Krogan04 2.48 0.0033 142GCR2_SM DT_Null Chitikila_02 2.48 0.0033 54

GCN4_RAPA hat1_vs.YPH250Rosaleny05 -2.48 0.0033 153GLN3_RAPA ISW2 Hughes00 2.48 0.0033 68MSN4_RAPA DT_V161R_K Chitikila_02 2.48 0.0033 52AFT2_H2O2Hi IES6 Hughes00 2.48 0.0033 61NRG1_H2O2Hispt10_del Xu05 -2.48 0.0033 121UME6_H2O2Hiisw2_rpd3_vs._rpd3Fazzio01 2.48 0.0033 98YAP7_H2O2Hi sap30_del Bernstein_00_affydeletions2.48 0.0033 137YAP7_H2O2Hi Dume1 Keogh05 2.48 0.0033 134AFT2_H2O2Lo TAF2 Mnaimneh_04 2.48 0.0033 98AFT2_H2O2Lo Hda1_del Bernstein02 2.48 0.0033 97YAP7_H2O2Lo YNG2 Mnaimneh_04 2.48 0.0033 152STE12_BUT14 ZDS1 Hughes00 2.48 0.0033 127GCN4_YPD snf2_rich_medium_experimentSudarsanam00 2.48 0.0033 73SWI4_YPD isw2_rpd3 Fazzio01 2.46 0.0034 152SWI6_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -2.46 0.0034 124YAP1_YPD ubp10sir4 Orlandi04 -2.46 0.0034 55YAP1_YPD 0.1%_MMS Attikum04 2.46 0.0034 62HSF1_H2O2Hi SIR1 Hughes00 2.46 0.0034 121MBP1_H2O2HiWT Durant06 2.46 0.0034 127MSN2_H2O2HiSIR3 Hughes00 2.46 0.0034 77MSN4_H2O2HiHTZ1 Krogan04 2.46 0.0034 66XBP1_H2O2Lo Set1_del Bernstein02 2.46 0.0034 68SOK2_BUT14 ume6 Fazzio01 2.46 0.0034 71HAP1_YPD spt10 Eriksson05 -2.46 0.0034 140SUT1_YPD gcn5D Durant06 2.45 0.0035 61SWI6_YPD taf1-ts2_GCN5Huisinga04 2.45 0.0035 145YAP6_YPD 0.1%_MMS Attikum04 -2.45 0.0035 65CBF1_SM arp8 Attikum04 -2.45 0.0035 229GLN3_RAPA esa1-414 Durant06 2.45 0.0035 61MSN4_H2O2Hitaf1-ts2_gcn5_KQLHuisinga04 2.45 0.0035 58SKN7_H2O2Hi taf1-ts2_gcn5 Huisinga04 2.45 0.0035 90UME6_H2O2Higcn5D_taf1-ts2Durant06 2.45 0.0035 95YAP6_H2O2Hi DT_N69S Chitikila_02 -2.45 0.0035 68DIG1_Alpha taf1-ts2_gcn5_KQLHuisinga04 2.45 0.0035 51MCM1_Alpha isw2_sin3 Fazzio01 2.45 0.0035 104ACE2_YPD esa1-414_taf1-ts2Durant06 2.45 0.0035 69HAP4_YPD DT_N69S Chitikila_02 -2.45 0.0035 63PHD1_YPD BUR6 Geisberg_01 2.44 0.0036 60RLM1_YPD 0.1%_MMS Attikum04 -2.44 0.0036 40STE12_YPD rpd3_del Sabet04 -2.44 0.0036 51SWI5_YPD MED2_haploid Hughes00 -2.44 0.0036 100SWI5_YPD MOT1-42 Dasgupta02 2.44 0.0036 100UME6_YPD H4_2-26 Sabet04 2.44 0.0036 129YAP1_YPD SGF11 Ingvarsdottir05 2.44 0.0036 65CBF1_SM rpd3_H3dN_v_H3dNSabet04 2.44 0.0036 271AFT2_H2O2Lo taf1-ts2_gcn5_KQLHuisinga04 2.44 0.0036 88MBP1_H2O2Lohat2_vs._YPH250Rosaleny05 -2.44 0.0036 54RPN4_H2O2Lotaf1-ts2_gcn5_KQLHuisinga04 2.44 0.0036 89DIG1_BUT14 SSD1-V Kaeberlein04 2.44 0.0036 63STE12_BUT14 MED2_haploid Hughes00 -2.44 0.0036 125HAP1_YPD taf1-ts2_gcn5 Huisinga04 2.44 0.0036 137YAP1_YPD TAF2 Mnaimneh_04 2.43 0.0037 71CBF1_SM SPT3 Ingvarsdottir05 2.43 0.0037 246

GCN4_RAPA DT_V71R Chitikila_02 2.43 0.0037 156MBP1_H2O2HiSIR3 Hughes00 -2.43 0.0037 133HSF1_H2O2LoUBP8 Hughes00 2.43 0.0037 99XBP1_H2O2Lo sas3D_taf1-ts2Durant06 -2.43 0.0037 55DIG1_Alpha RAD6_haploid Hughes00 -2.43 0.0037 57DIG1_BUT14 htz1_hmr Meneghini03 2.43 0.0037 63PHD1_BUT90 taf1-ts2_gcn5_KQLHuisinga04 2.43 0.0037 89ACE2_YPD gcn5D_taf1-ts2Durant06 2.43 0.0037 72MBP1_YPD htz1_hmr Meneghini03 2.43 0.0037 130NRG1_YPD htz1 Meneghini03 -2.43 0.0037 71ROX1_YPD hht2_K27G Martin04 -2.42 0.0038 41STE12_YPD sir2 Meneghini03 -2.42 0.0038 52SWI4_YPD sin3 Fazzio01 2.42 0.0038 152CBF1_SM DT_V161R_K Chitikila_02 -2.42 0.0038 265GCN4_RAPA DM_vs._YPH250Rosaleny05 2.42 0.0038 150GCN4_RAPA RPD3_haploid Hughes00 2.42 0.0038 159GCN4_RAPA H3KQ Sabet04 2.42 0.0038 157RTG3_RAPA SIN3 Hughes00 -2.42 0.0038 52AFT2_H2O2Hi ubp10 Orlandi04 2.42 0.0038 36MSN2_H2O2HiDrco1 Keogh05 2.42 0.0038 72RCS1_H2O2Lotaf1-ts2_spt3 Huisinga04 2.42 0.0038 246RIM101_H2O2LoHIR2 Hughes00 2.42 0.0038 53STE12_Alpha taf1-ts2_gcn5 Huisinga04 2.42 0.0038 108ACE2_YPD Drxt1 Keogh05 -2.42 0.0038 80HAP4_YPD SSN6_haploid Hughes00 2.42 0.0038 66MBP1_YPD SAP30 Hughes00 2.42 0.0038 128RLM1_YPD ARP4 Mnaimneh_04 2.4 0.0039 55ROX1_YPD swi1_rich_medium_experimentSudarsanam00 2.4 0.0039 66SKN7_YPD swi1_minimal_medium_experimentSudarsanam00 -2.4 0.0039 67SKN7_YPD gcn5_KQL Huisinga04 2.4 0.0039 54SWI4_YPD DT_V71E Chitikila_02 -2.4 0.0039 149YAP1_YPD WT_F182V Chitikila_02 2.4 0.0039 63GCN4_RAPA WT_V71R Chitikila_02 -2.4 0.0039 148MBP1_H2O2HiHIR2 Hughes00 -2.4 0.0039 130MBP1_H2O2HiARD1 Hughes00 -2.4 0.0039 133MSN2_H2O2Hispt3_E240K Huisinga04 2.4 0.0039 60MSN4_H2O2Hisir2 Meneghini03 2.4 0.0039 70REB1_H2O2Hi DT_N69S Chitikila_02 2.4 0.0039 53RCS1_H2O2Lodelta_ssd1 Kaeberlein04 2.4 0.0039 255XBP1_H2O2Lo Dsds3 Keogh05 -2.4 0.0039 57STE12_BUT14 elp3D Durant06 -2.4 0.0039 111STE12_BUT14 isw2_sin3 Fazzio01 -2.4 0.0039 127ACE2_YPD DM_vs._YPH250Rosaleny05 2.4 0.0039 74NDD1_YPD 0.1%_MMS Attikum04 -2.4 0.0039 74RLM1_YPD Hda1_del Bernstein02 2.39 0.004 53SUM1_YPD sir2 Meneghini03 2.39 0.004 55SWI4_YPD hpa2D Durant06 -2.39 0.004 121CBF1_SM isw2_sin3_vs._sin3Fazzio01 -2.39 0.004 272DAL81_RAPA sas3D Durant06 -2.39 0.004 79AFT2_H2O2Lo VID21 Krogan04 2.39 0.004 86CIN5_H2O2Lo DT_V161E Chitikila_02 -2.39 0.004 121HAP1_YPD sir2 Meneghini03 2.39 0.004 132HAP1_YPD DT_N69R Chitikila_02 -2.39 0.004 137

NDD1_YPD ISW1 Hughes00 2.39 0.004 85RLM1_YPD rpd3_c.i. Fazzio01 -2.38 0.0041 53RTG3_RAPA elp3D_taf1-ts2Durant06 2.38 0.0041 39HSF1_H2O2Hi hat2_vs._hat1Rosaleny05 -2.38 0.0041 119YAP6_H2O2Hi taf1-ts2_SPT3 Huisinga04 -2.38 0.0041 73YAP7_H2O2Hi MOT1-42 Dasgupta02 2.38 0.0041 140AFT2_H2O2Lo ino80_del Mizuguch04 2.38 0.0041 98SOK2_BUT14 esa1-414 Durant06 2.38 0.0041 61SOK2_BUT14 isw2_c.i._rpd3_c.i.Fazzio01 -2.38 0.0041 70ACE2_YPD _SWC2_(VPS72)Krogan04 2.38 0.0041 76HAP4_YPD Drpd3 Keogh05 -2.38 0.0041 62HAP4_YPD gcn5 Huisinga04 -2.38 0.0041 61PHD1_YPD sin3_del Bernstein_00_affydeletions-2.37 0.0042 58UME6_YPD WT_V71R Chitikila_02 -2.37 0.0042 113YAP1_YPD sir4 Orlandi04 -2.37 0.0042 53YAP6_YPD SIR3 Hughes00 2.37 0.0042 91CIN5_YPD WT_F182V Chitikila_02 2.37 0.0042 127DAL82_SM sap30_del Bernstein_00_affydeletions-2.37 0.0042 48DAL81_RAPA snf2_rich_medium_experimentSudarsanam00 2.37 0.0042 94DAL82_RAPA TAF2 Mnaimneh_04 -2.37 0.0042 56CIN5_H2O2Hi IES6 Hughes00 -2.37 0.0042 78SKN7_H2O2HiSSD1-V Kaeberlein04 2.37 0.0042 98RPN4_H2O2Losin3 Fazzio01 -2.37 0.0042 97YAP6_H2O2Lo htz1_hmr Meneghini03 -2.37 0.0042 58STE12_Alpha isw2_c.i._rpd3_c.i.Fazzio01 -2.37 0.0042 111SOK2_BUT14 Rpd3_del Bernstein02 -2.37 0.0042 71STE12_BUT14 SSD1-V Kaeberlein04 2.37 0.0042 127MGA1_YPD ISW1_ISW2 Hughes00 -2.37 0.0042 62NDD1_YPD htz1_sir2 Meneghini03 2.37 0.0042 84SKN7_YPD hht2_K27G Martin04 2.36 0.0043 51SWI4_YPD MED2_haploid Hughes00 -2.36 0.0043 156UME6_YPD sir4 Orlandi04 -2.36 0.0043 70GCR2_SM rsc3-2 Angus-Hill_01 -2.36 0.0043 52YAP6_H2O2Lo rpd3_c.i. Fazzio01 -2.36 0.0043 57DIG1_BUT14 htz1 Meneghini03 2.36 0.0043 62STE12_BUT90 RSC8 Mnaimneh_04 2.36 0.0043 78ACE2_YPD ino80 Attikum04 2.36 0.0043 65HAP1_YPD SPT8 Ingvarsdottir05 -2.36 0.0043 128MCM1_YPD hda1_del Bernstein_00_affydeletions-2.36 0.0043 69SKN7_YPD MED2_haploid Hughes00 -2.35 0.0044 66YAP6_YPD hos2_del Bernstein_00_affydeletions-2.35 0.0044 77CIN5_YPD rpd3_H3dN_v_H3dNSabet04 2.35 0.0044 144MSN4_H2O2HiDsin3 Keogh05 2.35 0.0044 64HSF1_H2O2LoHIR2 Hughes00 2.35 0.0044 100MBP1_H2O2LoSSD1-V Kaeberlein04 2.35 0.0044 57RCS1_H2O2LoSet1_del Bernstein02 -2.35 0.0044 252RPN4_H2O2LoHST3 Hughes00 2.35 0.0044 99YAP6_H2O2Lo ISW2 Hughes00 -2.35 0.0044 58YAP6_H2O2Lo sir2 Meneghini03 2.35 0.0044 58STE12_Alpha taf1-ts2_gcn5_KQLHuisinga04 2.35 0.0044 96SOK2_BUT14 WT_V71E Chitikila_02 -2.35 0.0044 58STE12_BUT14 isw2_c.i._rpd3_c.i.Fazzio01 -2.35 0.0044 127MBP1_YPD DT_V71R Chitikila_02 -2.35 0.0044 126

MGA1_YPD sin3 Fazzio01 -2.35 0.0044 60DAL81_RAPA _SWC2_(VPS72)Krogan04 2.34 0.0045 89GCN4_RAPA htz1_sir2 Meneghini03 2.34 0.0045 158MBP1_H2O2HiDT_V71E Chitikila_02 -2.34 0.0045 123MBP1_H2O2HiYNG2 Krogan04 2.34 0.0045 128YAP6_H2O2Hi htz1_hmr Meneghini03 -2.34 0.0045 78PUT3_H2O2Lo Set1_del Bernstein02 2.34 0.0045 88STE12_Alpha H3_1-28 Sabet04 -2.34 0.0045 109FKH2_YPD Dpho23 Keogh05 2.34 0.0045 121ACE2_YPD taf1-ts2_gcn5_KQLHuisinga04 2.34 0.0045 65NRG1_YPD htz1_del Mizuguch04 -2.34 0.0045 71PHO4_YPD EAF5 Krogan04 -2.33 0.0046 69SKN7_YPD IES6 Hughes00 2.33 0.0046 66SKN7_YPD WT_V71E Chitikila_02 -2.33 0.0046 58SUT1_YPD WT_V71E Chitikila_02 -2.33 0.0046 60SUT1_YPD WT_V161R_K Chitikila_02 -2.33 0.0046 64SWI5_YPD hpa2D_taf1-ts2Durant06 2.33 0.0046 76YAP1_YPD Dpho23 Keogh05 2.33 0.0046 72CIN5_YPD UBP8 Ingvarsdottir05 2.33 0.0046 138FKH2_H2O2Hi rpd3_c.i. Fazzio01 2.33 0.0046 104MBP1_H2O2Hidelta_ssd1 Kaeberlein04 2.33 0.0046 132MSN4_H2O2Hitaf1-ts2_spt3 Huisinga04 2.33 0.0046 67NRG1_H2O2Hihos2_del Bernstein_00_affydeletions-2.33 0.0046 112HSF1_H2O2Losas3D Durant06 2.33 0.0046 84XBP1_H2O2Lo H4KQ Sabet04 2.33 0.0046 56YAP7_H2O2Lo taf1-ts2_GCN5Huisinga04 2.33 0.0046 136DIG1_Alpha Drxt1 Keogh05 -2.33 0.0046 59STE12_Alpha hht2_K4914182327GMartin04 -2.33 0.0046 90ASH1_BUT14 hat1D_taf1-ts2Durant06 2.33 0.0046 39ASH1_BUT14 hpa2D Durant06 -2.33 0.0046 39PHD1_BUT90 swr1_del Mizuguch04 -2.33 0.0046 105PHD1_YPD Dsap30 Keogh05 -2.32 0.0047 64SWI6_YPD hat1D_taf1-ts2Durant06 2.32 0.0047 128CIN5_YPD sas3D_taf1-ts2Durant06 2.32 0.0047 131GCR2_SM ARD1 Hughes00 -2.32 0.0047 53GLN3_RAPA SIN3 Hughes00 -2.32 0.0047 68MBP1_H2O2HiEAF5 Krogan04 2.32 0.0047 115NRG1_H2O2Hisin3 Fazzio01 2.32 0.0047 123REB1_H2O2Hi DT_V161E Chitikila_02 2.32 0.0047 55SKN7_H2O2Hi sir4 Orlandi04 -2.32 0.0047 60AFT2_H2O2Lo swi1_minimal_medium_experimentSudarsanam00 2.32 0.0047 98AFT2_H2O2Lo hht2_K914182327GMartin04 2.32 0.0047 68CIN5_H2O2Lo taf1-ts2_25C Huisinga04 -2.32 0.0047 118RPN4_H2O2LoWT_V71R Chitikila_02 -2.32 0.0047 94SKN7_H2O2Losir2 Meneghini03 2.32 0.0047 183DIG1_BUT14 delta_ssd1 Kaeberlein04 2.32 0.0047 63PHD1_BUT90 isw2_rpd3 Fazzio01 -2.32 0.0047 103PHD1_BUT90 isw2_ume6 Fazzio01 2.32 0.0047 103HAP4_YPD EAF7 Krogan04 -2.32 0.0047 58PHD1_YPD htz1_hmr Meneghini03 -2.31 0.0048 66CIN5_YPD ino80_del Mizuguch04 -2.31 0.0048 150DAL81_RAPA RAD6_haploid Hughes00 2.31 0.0048 94GLN3_RAPA elp3D_taf1-ts2Durant06 2.31 0.0048 55

MBP1_H2O2HiSWR1 Krogan04 2.31 0.0048 125MBP1_H2O2HiWT_V161E Chitikila_02 -2.31 0.0048 122NRG1_H2O2Hihpa2D_taf1-ts2Durant06 2.31 0.0048 91YAP6_H2O2Hi RPD3_haploid Hughes00 -2.31 0.0048 78MBP1_H2O2Logcn5D Durant06 -2.31 0.0048 48SKN7_H2O2Loubp10 Orlandi04 2.31 0.0048 111XBP1_H2O2Lo ume6 Fazzio01 2.31 0.0048 64SOK2_BUT14 swi1_rich_medium_experimentSudarsanam00 2.31 0.0048 72SOK2_BUT14 Drxt1 Keogh05 -2.31 0.0048 69STE12_BUT14 WT_V71E Chitikila_02 -2.31 0.0048 107PHD1_BUT90 arp8_+_0.1%_MMS_vs._arp8Attikum04 -2.31 0.0048 79STE12_BUT90 SSD1-V Kaeberlein04 2.31 0.0048 77SWI6_YPD Deaf3 Keogh05 2.3 0.0049 147YAP1_YPD HST3 Hughes00 2.3 0.0049 71FKH2_H2O2Hi hht2_K4914182327GMartin04 2.3 0.0049 88UME6_H2O2Hitaf1-ts2 Durant06 2.3 0.0049 101YAP6_H2O2Hi sap30_del Bernstein_00_affydeletions-2.3 0.0049 68AFT2_H2O2Lo hat2_vs._YPH250Rosaleny05 2.3 0.0049 86RIM101_H2O2Lohat1D Durant06 -2.3 0.0049 39SKN7_H2O2LoSIR4 Hughes00 -2.3 0.0049 185SKN7_H2O2Lohos3_del Bernstein_00_affydeletions2.3 0.0049 162RLM1_YPD SIR1 Hughes00 2.3 0.005 53SKN7_YPD spt3_E240K Huisinga04 -2.3 0.005 59STE12_YPD HTZ1 Krogan04 2.3 0.005 50STE12_YPD ARD1 Hughes00 -2.3 0.005 54SUM1_YPD swr1 Meneghini03 -2.3 0.005 39SWI4_YPD isw2_c.i._rpd3_c.i.Fazzio01 2.3 0.005 151SWI6_YPD htz1_hmr Meneghini03 2.3 0.005 150CBF1_SM taf1-ts2_GCN5Huisinga04 2.3 0.005 261DAL82_RAPA taf1-ts2_gcn5_KQLHuisinga04 2.3 0.005 51GCN4_RAPA YNG2 Mnaimneh_04 2.3 0.005 160AFT2_H2O2Hi gcn5 Huisinga04 2.3 0.005 59CIN5_H2O2Hi elp3D Durant06 -2.3 0.005 67NRG1_H2O2Hiswi1_minimal_medium_experimentSudarsanam00 -2.3 0.005 124NRG1_H2O2HiUBP8 Ingvarsdottir05 2.3 0.005 116SKN7_H2O2Hi gcn5D_taf1-ts2Durant06 2.3 0.005 86SKN7_H2O2Hi isw2_rpd3 Fazzio01 -2.3 0.005 95SKN7_H2O2Loisw2_c.i._rpd3_c.i.Fazzio01 -2.3 0.005 180SKN7_H2O2LoDT_N69S Chitikila_02 -2.3 0.005 171XBP1_H2O2Lo esa1-414 Durant06 2.3 0.005 58YAP6_H2O2Lo gcn5D_taf1-ts2Durant06 -2.3 0.005 50YAP7_H2O2Lo isw2_sin3 Fazzio01 -2.3 0.005 148ASH1_BUT14 hda1_del Bernstein_00_affydeletions2.3 0.005 44DIG1_BUT14 esa1-414_taf1-ts2Durant06 2.3 0.005 59SOK2_BUT14 isw2_ume6 Fazzio01 2.3 0.005 71HAP1_YPD elp3D_taf1-ts2Durant06 2.3 0.005 122HAP1_YPD swr1 Meneghini03 2.3 0.005 108HAP4_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -2.3 0.005 48MCM1_YPD YAF9 Krogan04 2.3 0.005 73YAP1_YPD rsc30_null Angus-Hill_01 -2.29 0.0051 71CBF1_SM TAF2 Mnaimneh_04 2.29 0.0051 277GCR2_SM ume6 Fazzio01 -2.29 0.0051 52DAL81_RAPA gcn5 Huisinga04 2.29 0.0051 93

CIN5_H2O2Hi SWC6_(VPS71)Krogan04 -2.29 0.0051 69PUT3_H2O2Lo SSD1-V Kaeberlein04 2.29 0.0051 87PHD1_BUT90 ume6_del Bernstein_00_affydeletions2.29 0.0051 93FKH2_YPD taf1-ts2_gcn5 Huisinga04 -2.29 0.0051 112ACE2_YPD DT_V71E Chitikila_02 -2.29 0.0051 77HAP1_YPD TUP1_haploid Hughes00 2.29 0.0051 140HAP4_YPD taf1-ts2_spt3 Huisinga04 2.29 0.0051 64MBP1_YPD EAF5 Krogan04 2.29 0.0051 119NDD1_YPD H4KQ Sabet04 2.29 0.0051 83NRG1_YPD ino80 Attikum04 2.29 0.0051 38NRG1_YPD IES6 Hughes00 2.29 0.0051 72REB1_YPD rsc3-2 Angus-Hill_01 2.28 0.0052 140SUM1_YPD DT_Null Chitikila_02 -2.28 0.0052 51UME6_YPD WT_F182V Chitikila_02 2.28 0.0052 100DAL81_RAPA SIR3 Hughes00 2.28 0.0052 94GLN3_RAPA rpd3 Fazzio01 -2.28 0.0052 67GLN3_RAPA isw2_c.i._rpd3_c.i.Fazzio01 -2.28 0.0052 67MSN4_RAPA ISW1 Hughes00 -2.28 0.0052 54MBP1_H2O2HiSWC6_(VPS71)Krogan04 2.28 0.0052 120MBP1_H2O2Hihpa2D Durant06 -2.28 0.0052 109NRG1_H2O2HiH4_2-26 Sabet04 2.28 0.0052 120AFT2_H2O2Lo TUP1_haploid Hughes00 2.28 0.0052 98STE12_Alpha Ddep1 Keogh05 -2.28 0.0052 106GCN4_YPD taf1-ts2_25C Huisinga04 2.28 0.0052 69NRG1_YPD delta_ssd1 Kaeberlein04 -2.28 0.0052 72ABF1_YPD WT Durant06 2.27 0.0053 244PHD1_YPD hht2_K49141823GMartin04 2.27 0.0053 48SWI4_YPD SAP30 Hughes00 2.27 0.0053 156DAL82_RAPA isw2_sin3 Fazzio01 -2.27 0.0053 54DAL82_RAPA rpd3_H4KQ_v_H4KQSabet04 -2.27 0.0053 53FKH2_YPD swi1_minimal_medium_experimentSudarsanam00 -2.27 0.0053 121FKH2_YPD IOC4 Hughes00 2.27 0.0053 121HAP4_YPD isw2_c.i. Fazzio01 -2.27 0.0053 64UME6_YPD spt10_del Xu05 -2.26 0.0054 128CBF1_SM esa1-414_taf1-ts2Durant06 2.26 0.0054 258GCR2_SM Hda1_del Bernstein02 2.26 0.0054 54DAL81_RAPA spt10_del Xu05 -2.26 0.0054 95DAL81_RAPA Hda1_del Bernstein02 2.26 0.0054 94HSF1_H2O2Hi spt10_del Xu05 2.26 0.0054 122HSF1_H2O2Hi EAF5 Krogan04 2.26 0.0054 111NRG1_H2O2HiSPT8 Ingvarsdottir05 -2.26 0.0054 117NRG1_H2O2Hielp3D Durant06 -2.26 0.0054 101YAP6_H2O2Hi WT Durant06 -2.26 0.0054 73YAP6_H2O2Hi WT_V71R Chitikila_02 2.26 0.0054 69YAP7_H2O2Lo hat1_vs.YPH250Rosaleny05 2.26 0.0054 147DIG1_Alpha rpd3_c.i. Fazzio01 -2.26 0.0054 59ASH1_BUT14 DT_N69S Chitikila_02 -2.26 0.0054 48SOK2_BUT14 hht2_K4914182327GMartin04 2.26 0.0054 48STE12_BUT14 rpd3_H4KQ_v_H4KQSabet04 -2.26 0.0054 122ACE2_YPD isw2_sin3_vs._sin3Fazzio01 -2.26 0.0054 74HAP1_YPD RSC8 Mnaimneh_04 2.26 0.0054 141YAP1_YPD WT_V71E Chitikila_02 -2.25 0.0055 65YAP6_YPD Drco1 Keogh05 2.25 0.0055 84

GCN4_SM hat1D_taf1-ts2Durant06 2.25 0.0055 166GCR2_SM spt3 Huisinga04 -2.25 0.0055 53FKH2_H2O2Hi SSD1-V Kaeberlein04 2.25 0.0055 106FKH2_H2O2Hi gcn5_KQL Huisinga04 -2.25 0.0055 85NRG1_H2O2Hiisw2 Fazzio01 -2.25 0.0055 122SKN7_H2O2Lorsc3-2 Angus-Hill_01 -2.25 0.0055 184YAP6_H2O2Lo swr1 Meneghini03 -2.25 0.0055 48DIG1_Alpha HDA1 Hughes00 -2.25 0.0055 60HAP4_YPD YNG2 Krogan04 2.25 0.0055 57MCM1_YPD SIN3 Hughes00 2.25 0.0055 77NRG1_YPD swr1_del Mizuguch04 -2.25 0.0055 72ABF1_YPD _SWC2_(VPS72)Krogan04 2.25 0.0056 246CIN5_YPD UBP8 Hughes00 2.25 0.0056 150DAL81_RAPA swr1_del Mizuguch04 2.25 0.0056 95DAL82_RAPA rpd3_c.i. Fazzio01 -2.25 0.0056 54GLN3_RAPA TUP1_haploid Hughes00 2.25 0.0056 67RTG3_RAPA hpa2D_taf1-ts2Durant06 2.25 0.0056 39MBP1_H2O2Hi spt10_del Xu05 -2.25 0.0056 129MBP1_H2O2HiWT_Null_K Chitikila_02 2.25 0.0056 126MSN2_H2O2Hi_SWC2_(VPS72)Krogan04 2.25 0.0056 72SKN7_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 2.25 0.0056 82RIM101_H2O2LoSIR2 Hughes00 2.25 0.0056 53YAP6_H2O2Lo HDA1 Hughes00 2.25 0.0056 58YAP6_H2O2Lo rpd3_H4KQ_v_H4KQSabet04 -2.25 0.0056 51PHD1_BUT90 sin3 Fazzio01 -2.25 0.0056 103ACE2_YPD taf1-ts2_gcn5 Huisinga04 2.25 0.0056 75SUT1_YPD sas3D_taf1-ts2Durant06 2.24 0.0057 59SUT1_YPD Dpho23 Keogh05 -2.24 0.0057 66YAP1_YPD SIR3 Hughes00 2.24 0.0057 72MSN2_H2O2HiH3_1-28 Sabet04 2.24 0.0057 74STE12_Alpha SWD2 Mnaimneh_04 -2.24 0.0057 115SOK2_BUT14 H3KQ Sabet04 2.24 0.0057 65PHD1_BUT90 WT_Null_L Chitikila_02 2.24 0.0057 103HAP1_YPD hos3_del Bernstein_00_affydeletions2.24 0.0057 133ABF1_YPD SPT8 Ingvarsdottir05 2.23 0.0058 244SWI5_YPD esa1-414 Durant06 2.23 0.0058 95CBF1_SM taf1-ts2 Durant06 2.23 0.0058 269FKH2_H2O2Hi taf1-ts2_gcn5 Huisinga04 -2.23 0.0058 97HSF1_H2O2Hi gcn5D Durant06 2.23 0.0058 110HSF1_H2O2Hi gcn5 Huisinga04 -2.23 0.0058 115NRG1_H2O2HiYNG2 Krogan04 2.23 0.0058 122RCS1_H2O2Hi gcn5 Huisinga04 2.23 0.0058 49SKN7_H2O2Hi EAF7 Krogan04 2.23 0.0058 88YAP6_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 -2.23 0.0058 71MBP1_H2O2LoSWR1 Krogan04 2.23 0.0058 54SKN7_H2O2Lohtz1 Meneghini03 2.23 0.0058 184XBP1_H2O2Lo isw2_ume6 Fazzio01 2.23 0.0058 65STE12_Alpha rpd3_c.i. Fazzio01 -2.23 0.0058 112STE12_BUT14 sir4 Orlandi04 -2.23 0.0058 90GCN4_YPD Dsap30 Keogh05 2.23 0.0058 69REB1_YPD taf1-ts2_spt3 Huisinga04 2.22 0.0059 136RLM1_YPD SPT8 Ingvarsdottir05 -2.22 0.0059 51SKN7_H2O2Hi spt3_E240K Huisinga04 -2.22 0.0059 82

PUT3_H2O2Lo YNG2 Mnaimneh_04 2.22 0.0059 88MCM1_Alpha isw2_rpd3 Fazzio01 2.22 0.0059 103SOK2_BUT14 WT_N69R Chitikila_02 -2.22 0.0059 67PHD1_BUT90 YNG2 Mnaimneh_04 2.22 0.0059 106STE12_BUT90 sas3D_taf1-ts2Durant06 2.22 0.0059 69GCN4_YPD hat1D Durant06 -2.22 0.0059 57ROX1_YPD UBP8 Ingvarsdottir05 2.22 0.006 63SKN7_YPD SIR1 Hughes00 2.22 0.006 66SWI6_YPD WT_WT Chitikila_02 -2.22 0.006 148MSN4_RAPA WT_TAF1_SPT3Huisinga04 -2.22 0.006 53AFT2_H2O2Hi ino80 Attikum04 2.22 0.006 44MSN4_H2O2Hispt3_E240K Huisinga04 2.22 0.006 55YAP6_H2O2Hi SGF11 Ingvarsdottir05 2.22 0.006 67YAP6_H2O2Hi WT_V161R_K Chitikila_02 2.22 0.006 72CIN5_H2O2Lo ino80_+_0.1%_MMS_vs._ino80Attikum04 2.22 0.006 89RPN4_H2O2LoSPT8 Ingvarsdottir05 2.22 0.006 92RPN4_H2O2LoSSD1-V Kaeberlein04 2.22 0.006 100RPN4_H2O2Loisw2_c.i. Fazzio01 2.22 0.006 97SKN7_H2O2Lospt3 Huisinga04 -2.22 0.006 178HAP1_YPD SIR1 Hughes00 2.22 0.006 137SWI5_YPD IES6 Hughes00 2.21 0.0061 98SWI6_YPD EAF7 Krogan04 2.21 0.0061 144YAP1_YPD Dsin3 Keogh05 2.21 0.0061 61DAL82_RAPA RPD3_haploid Hughes00 -2.21 0.0061 55RTG3_RAPA hat1D_taf1-ts2Durant06 2.21 0.0061 45MBP1_H2O2Hi esa1-414_taf1-ts2Durant06 2.21 0.0061 127MSN2_H2O2Hirsc30_null Angus-Hill_01 -2.21 0.0061 77MSN4_H2O2Hihht2K9131823GMartin04 2.21 0.0061 63NRG1_H2O2Hitaf1-ts2_gcn5 Huisinga04 2.21 0.0061 116SKN7_H2O2Hi ino80_del Mizuguch04 2.21 0.0061 98YAP7_H2O2Hi htz1_sir2 Meneghini03 2.21 0.0061 137AFT2_H2O2Lo RAD6_haploid Hughes00 2.21 0.0061 97PUT3_H2O2Lo DT_V71R Chitikila_02 2.21 0.0061 84PHD1_BUT90 MOT1-14 Dasgupta02 2.21 0.0061 106OAF1_YPD RSC8 Mnaimneh_04 2.21 0.0061 59ABF1_YPD rpd3_c.i. Fazzio01 2.2 0.0062 263SUM1_YPD H4KQ Sabet04 2.2 0.0062 54HSF1_H2O2Hi SPT8 Ingvarsdottir05 2.2 0.0062 116MBP1_H2O2HiWT_V161R_L Chitikila_02 -2.2 0.0062 123RCS1_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 2.2 0.0062 36YAP6_H2O2Hi sir4 Orlandi04 -2.2 0.0062 37HSF1_H2O2Losnf2_minimal_medium_experimentSudarsanam00 2.2 0.0062 101XBP1_H2O2Lo Rpd3_del Bernstein02 -2.2 0.0062 68SOK2_BUT14 ARD1 Hughes00 -2.2 0.0062 72MCM1_YPD hht2K9131823GMartin04 2.2 0.0062 63ABF1_YPD WT_V161R_K Chitikila_02 2.2 0.0063 243REB1_YPD EAF5 Krogan04 -2.2 0.0063 131ROX1_YPD taf1-ts2_spt3 Huisinga04 -2.2 0.0063 63CIN5_YPD taf1-ts2_GCN5Huisinga04 2.2 0.0063 139GCR2_SM swr1 Meneghini03 2.2 0.0063 46GLN3_RAPA SIR3 Hughes00 2.2 0.0063 66HSF1_H2O2Hi ino80 Attikum04 -2.2 0.0063 103REB1_H2O2Hi SIR2 Hughes00 2.2 0.0063 58

YAP6_H2O2Hi swr1 Meneghini03 -2.2 0.0063 63YAP7_H2O2Hi SIR3 Hughes00 2.2 0.0063 141YAP7_H2O2Hi MOT1-14 Dasgupta02 2.2 0.0063 137AFT2_H2O2Lo gcn5_KQL Huisinga04 2.2 0.0063 89RIM101_H2O2Loino80_del Mizuguch04 2.2 0.0063 54YAP7_H2O2Lo rpd3_del Sabet04 2.2 0.0063 147STE12_BUT14 gcn5 Huisinga04 -2.2 0.0063 123MBP1_YPD Ddep1 Keogh05 2.2 0.0063 124RLM1_YPD Rpd3_del Bernstein02 -2.19 0.0064 53SUM1_YPD MOT1-14 Dasgupta02 2.19 0.0064 57SUT1_YPD VID21 Krogan04 2.19 0.0064 61SWI5_YPD MOT1-14 Dasgupta02 2.19 0.0064 99GCR2_SM htz1_sir2 Meneghini03 2.19 0.0064 52FKH2_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 2.19 0.0064 104MSN2_H2O2Hiubp10 Orlandi04 2.19 0.0064 49MSN2_H2O2HiSIR1 Hughes00 2.19 0.0064 77HSF1_H2O2LoEAF5 Krogan04 2.19 0.0064 90SKN7_H2O2LoIES6 Hughes00 2.19 0.0064 185YAP6_H2O2Lo hat1_vs.YPH250Rosaleny05 2.19 0.0064 54ASH1_BUT14 hht2_K914182327GMartin04 2.19 0.0064 42STE12_BUT14 taf1-ts2 Durant06 2.19 0.0064 125PHD1_BUT90 gcn5D Durant06 2.19 0.0064 88UME6_YPD htz1_sir2 Meneghini03 2.18 0.0065 127YAP6_YPD taf1-ts2_spt3 Huisinga04 -2.18 0.0065 84DAL82_RAPA VID21 Krogan04 2.18 0.0065 47GLN3_RAPA isw2_sin3_vs._sin3Fazzio01 -2.18 0.0065 67SKN7_H2O2Hi rpd3 Fazzio01 -2.18 0.0065 95AFT2_H2O2Lo hht2_K27G Martin04 2.18 0.0065 68RCS1_H2O2LoDT_WT Chitikila_02 2.18 0.0065 239GCN4_YPD ume6_del Bernstein_00_affydeletions2.18 0.0065 73ROX1_YPD SSN6_haploid Hughes00 2.18 0.0066 67GCN4_SM hat1_vs.YPH250Rosaleny05 -2.18 0.0066 180DAL81_RAPA Dsap30 Keogh05 -2.18 0.0066 90FKH2_H2O2Hi esa1-414_taf1-ts2Durant06 2.18 0.0066 94NRG1_H2O2HiDrxt1 Keogh05 -2.18 0.0066 125RPN4_H2O2LoSSN6_haploid Hughes00 2.18 0.0066 99RPN4_H2O2Loesa1-414 Durant06 -2.18 0.0066 92YAP7_H2O2Lo PCH1 Hughes00 2.18 0.0066 150STE12_Alpha taf1-ts2_spt3 Huisinga04 -2.18 0.0066 107PHD1_BUT90 ume6 Fazzio01 2.18 0.0066 103HAP1_YPD YNG2 Mnaimneh_04 2.18 0.0066 139SKN7_YPD HIR2 Hughes00 2.17 0.0067 64SWI5_YPD UBP8 Hughes00 2.17 0.0067 99YAP6_YPD taf1-ts2_GCN5Huisinga04 -2.17 0.0067 87GCR2_SM UBP8 Hughes00 2.17 0.0067 54GLN3_RAPA MOT1-14 Dasgupta02 2.17 0.0067 66YAP7_H2O2Lo isw2_ume6 Fazzio01 2.17 0.0067 148ASH1_BUT14 ume6_del Bernstein_00_affydeletions2.17 0.0067 44DIG1_BUT14 sap30_del Bernstein_00_affydeletions-2.17 0.0067 61MGA1_YPD Deaf3 Keogh05 -2.17 0.0067 57NDD1_YPD WT_WT Chitikila_02 -2.17 0.0067 83SWI6_YPD UBP8 Ingvarsdottir05 2.16 0.0068 145GCR2_SM sas3D Durant06 2.16 0.0068 50

GCR2_SM WT_Null_K Chitikila_02 2.16 0.0068 54DAL81_RAPA WT_F182V Chitikila_02 2.16 0.0068 77FKH2_H2O2Hi RAD6_haploid Hughes00 2.16 0.0068 105HSF1_H2O2Hi taf1-ts2_SPT3 Huisinga04 2.16 0.0068 121MSN2_H2O2HiDT_V161E Chitikila_02 -2.16 0.0068 76YAP6_H2O2Hi UBP8 Hughes00 2.16 0.0068 78MCM1_Alpha Ddep1 Keogh05 2.16 0.0068 102ASH1_BUT14 isw2_rpd3 Fazzio01 2.16 0.0068 49PHD1_BUT90 BUR6 Geisberg_01 2.16 0.0068 99ABF1_YPD hat1D_taf1-ts2Durant06 2.16 0.0069 225RLM1_YPD YAF9 Krogan04 2.16 0.0069 51ROX1_YPD ino80_del Mizuguch04 2.16 0.0069 65SUM1_YPD rpd3_H3dN_v_H3dNSabet04 -2.16 0.0069 53UME6_YPD RAD6_haploid Hughes00 2.16 0.0069 129UME6_YPD taf1-ts2_gcn5 Huisinga04 2.16 0.0069 125STP1_SM htz1_sir2 Meneghini03 2.16 0.0069 64GCN4_RAPA WT_TAF1_GCN5Huisinga04 2.16 0.0069 159AFT2_H2O2Lo Dsin3 Keogh05 2.16 0.0069 74RPN4_H2O2LoDT_N69R Chitikila_02 -2.16 0.0069 95XBP1_H2O2Lo ARP4 Mnaimneh_04 2.16 0.0069 68XBP1_H2O2Lo sir2 Meneghini03 2.16 0.0069 67FKH1_YPD rpd3 Fazzio01 2.16 0.0069 138HAP1_YPD hat1_vs.YPH250Rosaleny05 2.16 0.0069 135NDD1_YPD WT_V71R Chitikila_02 -2.16 0.0069 79NRG1_YPD ISW2 Hughes00 -2.16 0.0069 72CBF1_SM sin3 Fazzio01 2.15 0.007 272GCR2_SM hos2_del Bernstein_00_affydeletions2.15 0.007 51FKH2_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 -2.15 0.007 106SKN7_H2O2Hi hht2_K49141823GMartin04 2.15 0.007 73CIN5_H2O2Lo HST3 Hughes00 2.15 0.007 125STE12_Alpha hht2_K27G Martin04 -2.15 0.007 91ASH1_BUT14 gcn5D_taf1-ts2Durant06 2.15 0.007 44GCN4_YPD ARD1 Hughes00 2.15 0.007 75HAP4_YPD RAD6_haploid Hughes00 2.15 0.007 67HAP4_YPD taf1-ts2_GCN5Huisinga04 2.15 0.007 62STE12_YPD spt3_E240K Huisinga04 -2.14 0.0071 45UME6_YPD taf1-ts2_gcn5_KQLHuisinga04 2.14 0.0071 108GCN4_RAPA Rpd3_del Bernstein02 2.14 0.0071 160UME6_H2O2Hisas3D Durant06 2.14 0.0071 74RPN4_H2O2Loswi1_minimal_medium_experimentSudarsanam00 2.14 0.0071 100XBP1_H2O2Lo isw2_c.i. Fazzio01 -2.14 0.0071 65ASH1_BUT14 swi1_rich_medium_experimentSudarsanam00 2.14 0.0071 50FKH2_YPD Dsin3 Keogh05 2.14 0.0071 99ACE2_YPD ARP4 Mnaimneh_04 2.14 0.0071 80RLM1_YPD ZDS1 Hughes00 2.14 0.0072 55STE12_YPD MOT1-14 Dasgupta02 2.14 0.0072 52SUM1_YPD DT_V161R_L Chitikila_02 2.14 0.0072 50YAP6_YPD htz1_hmr Meneghini03 -2.14 0.0072 89FKH2_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 -2.14 0.0072 105SOK2_BUT14 ubp10 Orlandi04 2.14 0.0072 40SOK2_BUT14 sas3D_taf1-ts2Durant06 2.14 0.0072 61FKH2_YPD Ddep1 Keogh05 2.14 0.0072 115ROX1_YPD MED2_haploid Hughes00 2.13 0.0073 64

STE12_YPD sin3 Fazzio01 -2.13 0.0073 54SWI5_YPD Dsin3 Keogh05 2.13 0.0073 81DAL82_SM hat1_vs.YPH250Rosaleny05 2.13 0.0073 49CIN5_H2O2Hi DT_N69S Chitikila_02 -2.13 0.0073 74MSN4_H2O2Hispt10_del Xu05 2.13 0.0073 66HSF1_H2O2Loelp3D Durant06 2.13 0.0073 87RIM101_H2O2LoDT_V161R_L Chitikila_02 2.13 0.0073 50XBP1_H2O2Lo DT_V71R Chitikila_02 2.13 0.0073 66YAP7_H2O2Lo sir4 Orlandi04 -2.13 0.0073 99YAP7_H2O2Lo SIR2 Hughes00 2.13 0.0073 152DIG1_Alpha SWC6_(VPS71)Krogan04 2.13 0.0073 53HAP1_YPD hda1_del Bernstein_00_affydeletions2.13 0.0073 134SUT1_YPD taf1-ts2_spt3 Huisinga04 -2.13 0.0074 62CIN5_YPD taf1-ts2_gcn5_KQLHuisinga04 2.13 0.0074 117DAL81_RAPA Drco1 Keogh05 2.13 0.0074 90MBP1_H2O2HiEPL1 Mnaimneh_04 2.13 0.0074 133UME6_H2O2HiDrxt1 Keogh05 -2.13 0.0074 100YAP7_H2O2Hi Dsap30 Keogh05 2.13 0.0074 133AFT2_H2O2Lo YNG2 Krogan04 2.13 0.0074 88HSF1_H2O2Lospt3 Huisinga04 2.13 0.0074 96RCS1_H2O2Lohht2_K49141823GMartin04 2.13 0.0074 216YAP7_H2O2Lo htz1_sir2 Meneghini03 2.13 0.0074 146HAP1_YPD EAF5 Krogan04 2.13 0.0074 125PHO4_YPD sir4 Orlandi04 2.12 0.0075 47RLM1_YPD EPL1 Mnaimneh_04 2.12 0.0075 55STP1_SM sap30_del Bernstein_00_affydeletions-2.12 0.0075 64MSN4_H2O2Hisnf2_minimal_medium_experimentSudarsanam00 2.12 0.0075 70NRG1_H2O2HiPCH1 Hughes00 2.12 0.0075 124RPN4_H2O2LoDsin3 Keogh05 -2.12 0.0075 89XBP1_H2O2Lo DM_vs._YPH250Rosaleny05 2.12 0.0075 55STE12_BUT90 DT_V161R_L Chitikila_02 -2.12 0.0075 70FKH2_YPD SWC6_(VPS71)Krogan04 2.12 0.0075 108HAP4_YPD Ddep1 Keogh05 -2.12 0.0075 59NRG1_YPD snf2_minimal_medium_experimentSudarsanam00 2.12 0.0075 72NRG1_YPD Drxt2 Keogh05 -2.12 0.0075 68ABF1_YPD MOT1-42 Dasgupta02 -2.11 0.0076 265ABF1_YPD DT_N69R Chitikila_02 2.11 0.0076 248GCN4_SM arp8 Attikum04 -2.11 0.0076 157GLN3_RAPA HIR2 Hughes00 2.11 0.0076 67GLN3_RAPA Dpho23 Keogh05 -2.11 0.0076 68AFT2_H2O2Lo ubp10 Orlandi04 2.11 0.0076 54ASH1_BUT14 Set1_del Bernstein02 2.11 0.0076 48STE12_BUT14 rpd3_del Sabet04 -2.11 0.0076 122FKH2_YPD WT_WT Chitikila_02 -2.11 0.0076 118GCN4_YPD SIN3 Hughes00 -2.11 0.0076 75HAP1_YPD sas3D Durant06 2.11 0.0076 129ABF1_YPD taf1-ts2_GCN5Huisinga04 2.11 0.0077 248PHO4_YPD WT_V161R_L Chitikila_02 2.11 0.0077 70STE12_YPD DT_WT Chitikila_02 -2.11 0.0077 47SWI4_YPD ISW1 Hughes00 2.11 0.0077 156SWI6_YPD DT_V71R Chitikila_02 -2.11 0.0077 149UME6_YPD SWC6_(VPS71)Krogan04 2.11 0.0077 110CIN5_YPD hht2_K4G Martin04 -2.11 0.0077 114

GCN4_SM DT_N69S Chitikila_02 2.11 0.0077 178DAL81_RAPA sir2 Meneghini03 2.11 0.0077 92GLN3_RAPA Drpd3 Keogh05 2.11 0.0077 63HSF1_H2O2Hi WT_V71R Chitikila_02 -2.11 0.0077 115HSF1_H2O2Hi DT_N69S Chitikila_02 2.11 0.0077 119XBP1_H2O2Lo rpd3_del Sabet04 -2.11 0.0077 56PHD1_BUT90 snf2_minimal_medium_experimentSudarsanam00 2.11 0.0077 106FKH2_YPD sir4 Orlandi04 -2.11 0.0077 82SWI6_YPD delta_ssd1 Kaeberlein04 2.1 0.0078 150GCR2_SM WT_V161E Chitikila_02 -2.1 0.0078 49DAL82_RAPA SIN3 Hughes00 -2.1 0.0078 55MBP1_H2O2Logcn5_KQL Huisinga04 -2.1 0.0078 52ASH1_BUT14 EAF7 Krogan04 2.1 0.0078 45ASH1_BUT14 hht2_K4914182327GMartin04 2.1 0.0078 41PHD1_BUT90 VID21 Krogan04 2.1 0.0078 96YAP1_YPD SIR4 Hughes00 2.1 0.0079 71CIN5_YPD rpd3 Fazzio01 -2.1 0.0079 148GCN4_SM WT_V161R_L Chitikila_02 -2.1 0.0079 183HSF1_H2O2Hi rpd3_del Sabet04 -2.1 0.0079 122MBP1_H2O2Hi ino80_del Mizuguch04 -2.1 0.0079 133MSN4_H2O2Hispt3 Huisinga04 2.1 0.0079 66RCS1_H2O2Lohht2_K27G Martin04 2.1 0.0079 219DIG1_BUT14 rpd3_H3dN_v_H3dNSabet04 -2.1 0.0079 63PHD1_BUT90 hht2_K914182327GMartin04 2.1 0.0079 78GCN4_YPD WT_N69R Chitikila_02 -2.1 0.0079 71HAP4_YPD hos2_del Bernstein_00_affydeletions2.1 0.0079 57MCM1_YPD _SWC2_(VPS72)Krogan04 2.1 0.0079 74ABF1_YPD WT_V161R_L Chitikila_02 2.09 0.008 252ABF1_YPD WT_V71R Chitikila_02 2.09 0.008 243PHD1_YPD htz1 Meneghini03 -2.09 0.008 67SKN7_YPD WT_Null_L Chitikila_02 2.09 0.008 64YAP6_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -2.09 0.008 67RTG3_RAPA SSD1-V Kaeberlein04 -2.09 0.008 52FKH2_H2O2Hi WT_WT Chitikila_02 -2.09 0.008 99CIN5_H2O2Lo sir4 Orlandi04 -2.09 0.008 65PHD1_BUT90 taf1-ts2_GCN5Huisinga04 2.09 0.008 101ABF1_YPD rsc3-2 Angus-Hill_01 2.09 0.0081 261GCN4_RAPA WT_N69S Chitikila_02 -2.09 0.0081 148MBP1_H2O2Hi IES6 Hughes00 -2.09 0.0081 133MSN4_H2O2HiSAP30 Hughes00 2.09 0.0081 69REB1_H2O2Hi DT_V71E Chitikila_02 2.09 0.0081 58YAP7_H2O2Hi spt10_del Xu05 2.09 0.0081 136PHD1_BUT90 sin3_del Bernstein_00_affydeletions-2.09 0.0081 87SWI4_YPD EAF5 Krogan04 2.08 0.0082 139GCR2_SM rpd3 Fazzio01 -2.08 0.0082 52GCR2_SM WT_V71E Chitikila_02 -2.08 0.0082 51MSN2_H2O2HiDsds3 Keogh05 2.08 0.0082 71YAP6_H2O2Hi swi1_rich_medium_experimentSudarsanam00 2.08 0.0082 79SKN7_H2O2LoEAF5 Krogan04 2.08 0.0082 160DIG1_Alpha BUR6 Geisberg_01 2.08 0.0082 55STE12_BUT14 WT_TAF1_GCN5Huisinga04 2.08 0.0082 127NDD1_YPD gcn5 Huisinga04 -2.08 0.0082 83SKN7_YPD WT_F182V Chitikila_02 2.08 0.0083 55

YAP6_YPD DM_vs._YPH250Rosaleny05 2.08 0.0083 80YAP6_YPD DT_N69S Chitikila_02 -2.08 0.0083 81AFT2_H2O2Hi Set1_del Bernstein02 2.08 0.0083 61YAP7_H2O2Hi taf1-ts2_GCN5Huisinga04 2.08 0.0083 129CIN5_H2O2Lo WT_V161E Chitikila_02 -2.08 0.0083 118PUT3_H2O2Lo PCH1 Hughes00 2.08 0.0083 87RIM101_H2O2LoDume1 Keogh05 -2.08 0.0083 52STE12_Alpha swr1_del Mizuguch04 2.08 0.0083 115STE12_BUT14 BUR6 Geisberg_01 2.08 0.0083 121STE12_BUT14 DT_WT Chitikila_02 -2.08 0.0083 123FKH2_YPD DT_WT Chitikila_02 -2.08 0.0083 115ACE2_YPD Drco1 Keogh05 2.08 0.0083 75NRG1_YPD SWR1 Krogan04 -2.08 0.0083 66SUT1_YPD WT_N69R Chitikila_02 -2.07 0.0084 64UME6_YPD ubp10 Orlandi04 2.07 0.0084 66SKN7_H2O2Hi IES6 Hughes00 2.07 0.0084 97YAP6_H2O2Hi Dsap30 Keogh05 -2.07 0.0084 75AFT2_H2O2Lo isw2_sin3_vs._sin3Fazzio01 -2.07 0.0084 95RCS1_H2O2LoRPD3_haploid Hughes00 2.07 0.0084 251MCM1_Alpha taf1-ts2_GCN5Huisinga04 2.07 0.0084 103ASH1_BUT14 htz1_hmr Meneghini03 2.07 0.0084 48SOK2_BUT14 taf1-ts2_gcn5 Huisinga04 2.07 0.0084 71FKH2_YPD rpd3 Fazzio01 2.07 0.0084 119GCN4_YPD WT_TAF1_GCN5Huisinga04 2.07 0.0084 74MGA1_YPD ume6_del Bernstein_00_affydeletions-2.07 0.0084 60MBP1_H2O2Lohat1_vs.YPH250Rosaleny05 2.07 0.0085 54XBP1_H2O2Lo rsc3-2 Angus-Hill_01 2.07 0.0085 67YAP6_H2O2Lo MOT1-14 Dasgupta02 2.07 0.0085 58MCM1_Alpha htz1 Meneghini03 2.07 0.0085 106STE12_BUT90 delta_ssd1 Kaeberlein04 2.07 0.0085 77NRG1_YPD swi1_minimal_medium_experimentSudarsanam00 2.07 0.0085 72NRG1_YPD hos3_del Bernstein_00_affydeletions-2.07 0.0085 52HSF1_H2O2Hi EAF7 Krogan04 2.06 0.0086 116MSN4_H2O2HiH4KQ Sabet04 2.06 0.0086 65UME6_H2O2Hitaf1-ts2_25C Huisinga04 2.06 0.0086 98YAP6_H2O2Hi isw2_sin3_vs._sin3Fazzio01 -2.06 0.0086 73PHD1_BUT90 Dpho23 Keogh05 -2.06 0.0086 103STE12_BUT90 SIR2 Hughes00 -2.06 0.0086 77ACE2_YPD IOC4 Hughes00 -2.06 0.0086 80NDD1_YPD ARD1 Hughes00 -2.06 0.0086 85STE12_YPD VID21 Krogan04 2.06 0.0087 45SUT1_YPD H4_2-26 Sabet04 2.06 0.0087 66CIN5_YPD WT_V161E Chitikila_02 -2.06 0.0087 143CBF1_SM gcn5D Durant06 2.06 0.0087 234DAL82_SM spt3 Huisinga04 -2.06 0.0087 53GCR2_SM delta_ssd1 Kaeberlein04 2.06 0.0087 54GCN4_RAPA hht2_K49141823GMartin04 2.06 0.0087 134RTG3_RAPA ISW1 Hughes00 -2.06 0.0087 52HSF1_H2O2Hi hat1_vs.YPH250Rosaleny05 2.06 0.0087 118MSN4_H2O2HiH3_1-28 Sabet04 2.06 0.0087 65SKN7_H2O2Hi ubp10sir4 Orlandi04 -2.06 0.0087 62MCM1_Alpha UBP8 Hughes00 -2.06 0.0087 106STE12_YPD rsc30_null Angus-Hill_01 -2.05 0.0088 51

CIN5_YPD hos3_del Bernstein_00_affydeletions-2.05 0.0088 138GCR2_SM ume6_del Bernstein_00_affydeletions2.05 0.0088 52DIG1_BUT14 swi1_rich_medium_experimentSudarsanam00 -2.05 0.0088 63FKH1_YPD isw2_c.i._rpd3_c.i.Fazzio01 2.05 0.0088 138GCN4_SM H3KQ Sabet04 2.05 0.0089 185GLN3_RAPA UBP8 Hughes00 2.05 0.0089 68MSN2_H2O2HiMOT1-42 Dasgupta02 2.05 0.0089 78AFT2_H2O2Lo arp8_+_0.1%_MMS_vs._arp8Attikum04 2.05 0.0089 72SOK2_BUT14 Ddep1 Keogh05 -2.05 0.0089 70PHD1_BUT90 hht2_K4G Martin04 -2.05 0.0089 80MGA1_YPD Drco1 Keogh05 -2.05 0.0089 62SKN7_YPD rpd3_H4KQ_v_H4KQSabet04 -2.04 0.009 62UME6_YPD hpa2D_taf1-ts2Durant06 2.04 0.009 95RTG3_RAPA snf2_rich_medium_experimentSudarsanam00 2.04 0.009 51CIN5_H2O2Hi rpd3_c.i. Fazzio01 -2.04 0.009 79PUT3_H2O2Lo SGF11 Ingvarsdottir05 2.04 0.009 71YAP6_H2O2Lo Dpho23 Keogh05 -2.04 0.009 58HAP4_YPD esa1-414_taf1-ts2Durant06 2.04 0.009 58HAP4_YPD WT_N69S Chitikila_02 -2.04 0.009 64MGA1_YPD SIR1 Hughes00 -2.04 0.009 61ROX1_YPD DM_vs._YPH250Rosaleny05 2.04 0.0091 58STE12_YPD Set1_del Bernstein02 -2.04 0.0091 52SWI4_YPD taf1-ts2_gcn5 Huisinga04 -2.04 0.0091 151GCN4_SM MED2_haploid Hughes00 -2.04 0.0091 187REB1_H2O2Hi hht2_K4914182327GMartin04 2.04 0.0091 51CIN5_H2O2Lo Drxt1 Keogh05 -2.04 0.0091 126FKH2_YPD WT_N69S Chitikila_02 -2.04 0.0091 108FKH2_YPD WT_V161R_L Chitikila_02 -2.04 0.0091 116HAP1_YPD sap30_del Bernstein_00_affydeletions2.04 0.0091 134MCM1_YPD ISW1_ISW2 Hughes00 2.04 0.0091 77RLM1_YPD taf1-ts2 Durant06 2.03 0.0092 52PHD1_BUT90 taf1-ts2_spt3_E240KHuisinga04 -2.03 0.0092 95MGA1_YPD SIN3 Hughes00 -2.03 0.0092 62REB1_H2O2Hi WT_V161E Chitikila_02 2.03 0.0093 56MBP1_H2O2Lotaf1-ts2_spt3 Huisinga04 -2.03 0.0093 55RCS1_H2O2Logcn5D_taf1-ts2Durant06 2.03 0.0093 240MCM1_Alpha isw2_c.i._rpd3_c.i.Fazzio01 2.03 0.0093 104ABF1_YPD snf2_rich_medium_experimentSudarsanam00 -2.02 0.0094 267DAL81_RAPA Rpd3_del Bernstein02 2.02 0.0094 93DAL82_RAPA spt3 Huisinga04 -2.02 0.0094 53MSN4_H2O2Hisap30_del Bernstein_00_affydeletions2.02 0.0094 63MSN4_H2O2HiH4_2-26 Sabet04 2.02 0.0094 65MSN4_H2O2HiDeaf3 Keogh05 2.02 0.0094 64FKH1_YPD isw2_sin3 Fazzio01 2.02 0.0094 139SOK2_BUT14 gcn5_KQL Huisinga04 2.02 0.0094 63PHD1_YPD swi1_rich_medium_experimentSudarsanam00 2.02 0.0095 67ROX1_YPD spt3_E240K Huisinga04 -2.02 0.0095 61SWI6_YPD Drpd3 Keogh05 2.02 0.0095 144DAL81_RAPA SSD1-V Kaeberlein04 2.02 0.0095 95DAL82_RAPA Ddep1 Keogh05 -2.02 0.0095 54NRG1_H2O2HiWT_F182V Chitikila_02 2.02 0.0095 104RCS1_H2O2Hi SPT3 Ingvarsdottir05 2.02 0.0095 40MBP1_H2O2LoWT_N69R Chitikila_02 -2.02 0.0095 51

STE12_Alpha ARP4 Mnaimneh_04 2.02 0.0095 115ASH1_BUT14 DT_V161E Chitikila_02 -2.02 0.0095 48STE12_BUT14 swi1_rich_medium_experimentSudarsanam00 -2.02 0.0095 128FKH2_YPD TUP1_haploid Hughes00 -2.02 0.0095 120RLM1_YPD rpd3_H4KQ_v_H4KQSabet04 -2.01 0.0096 50SKN7_YPD EAF7 Krogan04 2.01 0.0096 58SKN7_YPD WT_Null_K Chitikila_02 -2.01 0.0096 67GLN3_RAPA PCH1 Hughes00 2.01 0.0096 67MSN2_H2O2Hihht2_K27G Martin04 2.01 0.0096 63NRG1_H2O2HiUBP8 Hughes00 2.01 0.0096 123NRG1_H2O2Hiisw2_rpd3_vs._rpd3Fazzio01 -2.01 0.0096 123YAP6_H2O2Hi MOT1-14 Dasgupta02 2.01 0.0096 79YAP6_H2O2Hi DT_V161E Chitikila_02 -2.01 0.0096 73YAP6_H2O2Lo Dsin3 Keogh05 -2.01 0.0096 53STE12_Alpha H3KQ Sabet04 -2.01 0.0096 109ASH1_BUT14 WT_V71R Chitikila_02 -2.01 0.0096 44NDD1_YPD taf1-ts2_GCN5Huisinga04 2.01 0.0096 82SUT1_YPD sin3_del Bernstein_00_affydeletions-2.01 0.0097 60YAP6_YPD Drxt1 Keogh05 -2.01 0.0097 89GLN3_RAPA taf1-ts2_spt3_E240KHuisinga04 2.01 0.0097 63FKH2_H2O2Hi WT_V71E Chitikila_02 -2.01 0.0097 89UME6_H2O2Hisap30_del Bernstein_00_affydeletions2.01 0.0097 98AFT2_H2O2Lo ume6 Fazzio01 2.01 0.0097 94CIN5_H2O2Lo YNG2 Mnaimneh_04 2.01 0.0097 127STE12_Alpha SWR1 Krogan04 2.01 0.0097 110HAP4_YPD SWR1 Krogan04 2.01 0.0097 55YAP7_H2O2Hi SWR1 Krogan04 2 0.0098 127PUT3_H2O2Lo DT_V161R_L Chitikila_02 2 0.0098 81STE12_Alpha HTZ1 Krogan04 2 0.0098 110GCN4_YPD ino80 Attikum04 -2 0.0098 65ABF1_YPD DT_WT Chitikila_02 2 0.0099 248SUT1_YPD Drxt1 Keogh05 -2 0.0099 66AFT2_H2O2Hi arp8 Attikum04 2 0.0099 43FKH2_H2O2Hi hht2K9131823GMartin04 2 0.0099 88MSN2_H2O2HiSIR4 Hughes00 -2 0.0099 77NRG1_H2O2Hisnf2_rich_medium_experimentSudarsanam00 2 0.0099 123SKN7_H2O2LoDsds3 Keogh05 2 0.0099 165ASH1_BUT14 WT Durant06 -2 0.0099 46SOK2_BUT14 _SWC2_(VPS72)Krogan04 2 0.0099 69NDD1_YPD UBP8 Ingvarsdottir05 2 0.0099 81RLM1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.99 0.01 40ROX1_YPD sas3D_taf1-ts2Durant06 -1.99 0.01 55SKN7_YPD sir4 Orlandi04 -1.99 0.01 42SUT1_YPD rpd3_H4KQ_v_H4KQSabet04 -1.99 0.01 66SWI4_YPD ZDS1 Hughes00 1.99 0.01 152SWI4_YPD hda1_del Bernstein_00_affydeletions1.99 0.01 146DAL81_RAPA rsc30_null Angus-Hill_01 -1.99 0.01 92AFT2_H2O2Hi Rpd3_del Bernstein02 1.99 0.01 61RCS1_H2O2Hi Set1_del Bernstein02 1.99 0.01 52SKN7_H2O2HiH4KQ Sabet04 1.99 0.01 92AFT2_H2O2Lo SSD1-V Kaeberlein04 1.99 0.01 98AFT2_H2O2Lo isw2_ume6 Fazzio01 1.99 0.01 95SOK2_BUT14 H3_1-28 Sabet04 1.99 0.01 65

FKH2_YPD rpd3_c.i. Fazzio01 1.99 0.01 119NDD1_YPD SIR2 Hughes00 -1.99 0.01 83ABF1_YPD hht2_K4914182327GMartin04 1.99 0.0101 233SWI4_YPD H4KQ Sabet04 1.99 0.0101 151HSF1_H2O2LoRPD3_haploid Hughes00 -1.99 0.0101 100STE12_BUT90 esa1-414_taf1-ts2Durant06 1.99 0.0101 73GCN4_YPD rpd3_H3dN_v_H3dNSabet04 1.99 0.0101 75HAP1_YPD DT_N69S Chitikila_02 -1.99 0.0101 134HAP4_YPD SIR1 Hughes00 1.99 0.0101 66SKN7_YPD HDA1 Hughes00 1.99 0.0102 66SUM1_YPD WT_N69R Chitikila_02 1.99 0.0102 51CBF1_SM sir4 Orlandi04 -1.99 0.0102 203UME6_H2O2HiH4_2-26 Sabet04 1.99 0.0102 99YAP7_H2O2Hi sir4 Orlandi04 -1.99 0.0102 102YAP7_H2O2Lo spt10 Eriksson05 1.99 0.0102 150FKH1_YPD VID21 Krogan04 -1.99 0.0102 132SOK2_BUT14 isw2_sin3 Fazzio01 -1.99 0.0102 71STE12_BUT14 spt3 Huisinga04 -1.99 0.0102 121TYE7_YPD rpd3_H4KQ_v_H4KQSabet04 -1.98 0.0103 55DAL81_RAPA BUR6 Geisberg_01 1.98 0.0103 89GLN3_RAPA H3KQ Sabet04 1.98 0.0103 66MSN4_RAPA rpd3_H3dN_v_H3dNSabet04 -1.98 0.0103 52CIN5_H2O2Hi RPD3_haploid Hughes00 -1.98 0.0103 79YAP6_H2O2Hi taf1-ts2_spt3 Huisinga04 -1.98 0.0103 72SOK2_BUT14 Dume1 Keogh05 -1.98 0.0103 64STE12_BUT14 isw2_sin3_vs._sin3Fazzio01 -1.98 0.0103 126NRG1_YPD taf1-ts2_SPT3 Huisinga04 -1.98 0.0103 65ABF1_YPD delta_ssd1 Kaeberlein04 1.98 0.0104 267DAL82_RAPA hmr Meneghini03 -1.98 0.0104 52SKN7_H2O2Hi hht2_K27G Martin04 1.98 0.0104 72SOK2_BUT14 ino80_+_0.1%_MMS_vs._ino80Attikum04 -1.98 0.0104 48YAP6_YPD rpd3_H4KQ_v_H4KQSabet04 -1.97 0.0105 82RCS1_H2O2Hi rpd3_c.i. Fazzio01 -1.97 0.0105 50SKN7_H2O2Hi TAF2 Mnaimneh_04 1.97 0.0105 98YAP7_H2O2Hi isw2_rpd3 Fazzio01 -1.97 0.0105 137CIN5_H2O2Lo rpd3_H4KQ_v_H4KQSabet04 -1.97 0.0105 119HSF1_H2O2Lohpa2D Durant06 -1.97 0.0105 83RCS1_H2O2LoISW1_ISW2 Hughes00 -1.97 0.0105 256MCM1_YPD swr1_del Mizuguch04 1.97 0.0105 77STE12_YPD swi1_minimal_medium_experimentSudarsanam00 -1.97 0.0106 52GLN3_RAPA ISW1_ISW2 Hughes00 1.97 0.0106 68MSN2_H2O2HiEPL1 Mnaimneh_04 1.97 0.0106 78UME6_H2O2Hiisw2_sin3_vs._sin3Fazzio01 1.97 0.0106 98AFT2_H2O2Lo HDA1 Hughes00 1.97 0.0106 98RIM101_H2O2Lohat1D_taf1-ts2Durant06 -1.97 0.0106 41SKN7_H2O2LoISW1_ISW2 Hughes00 1.97 0.0106 185HAP4_YPD DT_V161R_K Chitikila_02 -1.97 0.0106 65PHO4_YPD DT_V161R_K Chitikila_02 1.97 0.0107 70ROX1_YPD hat1D_taf1-ts2Durant06 -1.97 0.0107 53SWI4_YPD gcn5D_taf1-ts2Durant06 1.97 0.0107 144DAL82_SM WT_F182V Chitikila_02 1.97 0.0107 46AFT2_H2O2Hi SIR3 Hughes00 1.97 0.0107 60YAP6_H2O2Lo hht2_K27G Martin04 -1.97 0.0107 34

DIG1_Alpha MOT1-14 Dasgupta02 1.97 0.0107 59DIG1_Alpha swr1 Meneghini03 -1.97 0.0107 50STE12_BUT14 isw2_c.i. Fazzio01 1.97 0.0107 127ROX1_YPD HDA1 Hughes00 1.96 0.0108 67SUM1_YPD RSC8 Mnaimneh_04 1.96 0.0108 59DAL82_RAPA rpd3 Fazzio01 -1.96 0.0108 54NRG1_H2O2Hisnf2_minimal_medium_experimentSudarsanam00 1.96 0.0108 124YAP6_H2O2Lo taf1-ts2_SPT3 Huisinga04 -1.96 0.0108 52FKH2_YPD _SWC2_(VPS72)Krogan04 1.96 0.0108 116NRG1_YPD HST3 Hughes00 1.96 0.0108 72SUT1_YPD sin3 Fazzio01 -1.96 0.0109 69CIN5_YPD rpd3_H4KQ_v_H4KQSabet04 -1.96 0.0109 144MSN4_RAPA hht2_K4914182327GMartin04 -1.96 0.0109 36AFT2_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 1.96 0.0109 61HSF1_H2O2Hi HDA1 Hughes00 -1.96 0.0109 121MSN4_H2O2Hihpa2D Durant06 -1.96 0.0109 60RIM101_H2O2LoISW1 Hughes00 1.96 0.0109 53RIM101_H2O2LoDrxt1 Keogh05 -1.96 0.0109 53XBP1_H2O2Lo DT_N69S Chitikila_02 -1.96 0.0109 61XBP1_H2O2Lo spt3_E240K Huisinga04 -1.96 0.0109 62MCM1_Alpha DM_vs._YPH250Rosaleny05 1.96 0.0109 96ASH1_BUT14 _SWC2_(VPS72)Krogan04 1.96 0.0109 48MGA1_YPD H4_2-26 Sabet04 -1.96 0.0109 61SUT1_YPD hos2_del Bernstein_00_affydeletions-1.95 0.011 60GCN4_SM spt10 Eriksson05 -1.95 0.011 186STP1_SM ISW1 Hughes00 -1.95 0.011 68RCS1_H2O2Hi sap30_del Bernstein_00_affydeletions1.95 0.011 47REB1_H2O2Hi delta_ssd1 Kaeberlein04 1.95 0.011 58SKN7_H2O2Hi ISW1 Hughes00 1.95 0.011 96CIN5_H2O2Lo DT_V71E Chitikila_02 -1.95 0.011 121STE12_BUT14 _SWC2_(VPS72)Krogan04 1.95 0.011 120GCN4_YPD spt3_E240K Huisinga04 1.95 0.011 67HAP4_YPD set1 Boa03 -1.95 0.011 65CIN5_H2O2Hi snf2_rich_medium_experimentSudarsanam00 1.95 0.0111 79SKN7_H2O2HiRPD3_haploid Hughes00 1.95 0.0111 97YAP7_H2O2Hi hht2_K49141823GMartin04 1.95 0.0111 117RIM101_H2O2LoDT_N69R Chitikila_02 1.95 0.0111 48ASH1_BUT14 H4_2-26 Sabet04 1.95 0.0111 47DIG1_BUT14 RAD6_haploid Hughes00 -1.95 0.0111 63PHD1_BUT90 hpa2D Durant06 -1.95 0.0111 80NRG1_YPD WT_N69R Chitikila_02 1.95 0.0111 66SWI6_YPD htz1_sir2 Meneghini03 1.95 0.0112 150DAL81_RAPA ubp10 Orlandi04 -1.95 0.0112 67DAL81_RAPA EPL1 Mnaimneh_04 1.95 0.0112 95RTG3_RAPA ume6 Fazzio01 1.95 0.0112 51CIN5_H2O2Hi sir2 Meneghini03 1.95 0.0112 79YAP6_H2O2Lo Ddep1 Keogh05 -1.95 0.0112 57GCN4_YPD swi1_minimal_medium_experimentSudarsanam00 -1.95 0.0112 75DAL82_RAPA sas3D Durant06 -1.94 0.0113 42HSF1_H2O2Hi HIR2 Hughes00 1.94 0.0113 121MSN2_H2O2HiHIR2 Hughes00 1.94 0.0113 77YAP7_H2O2Hi H4_2-26 Sabet04 1.94 0.0113 136AFT2_H2O2Lo EPL1 Mnaimneh_04 1.94 0.0113 98

ASH1_BUT14 hat2_vs._hat1Rosaleny05 -1.94 0.0113 45ASH1_BUT14 hht2_K4G Martin04 1.94 0.0113 39STE12_BUT14 Dume1 Keogh05 -1.94 0.0113 115FKH2_YPD WT_N69R Chitikila_02 -1.94 0.0113 110MGA1_YPD WT_F182V Chitikila_02 -1.94 0.0113 47NDD1_YPD htz1_del Mizuguch04 1.94 0.0113 85REB1_YPD Set1_del Bernstein02 -1.94 0.0114 140SWI5_YPD ISW1_ISW2 Hughes00 -1.94 0.0114 100MSN4_RAPA taf1-ts2_spt3 Huisinga04 1.94 0.0114 51SOK2_BUT14 gcn5D Durant06 1.94 0.0114 58YAP6_YPD WT_TAF1_GCN5Huisinga04 -1.93 0.0115 90GCN4_RAPA hat1D_taf1-ts2Durant06 1.93 0.0115 142SKN7_H2O2Lospt10_del Xu05 1.93 0.0115 181YAP6_H2O2Lo Dsds3 Keogh05 -1.93 0.0115 51RLM1_YPD gcn5_KQL Huisinga04 -1.93 0.0116 46SUM1_YPD rpd3_del Sabet04 -1.93 0.0116 53SWI6_YPD DT_V161R_K Chitikila_02 -1.93 0.0116 148RTG3_RAPA 0.1%_MMS Attikum04 1.93 0.0116 43MBP1_H2O2Lohht2_K4914182327GMartin04 1.93 0.0116 47ABF1_YPD ubp10sir4 Orlandi04 -1.93 0.0117 227ABF1_YPD rsc30_null Angus-Hill_01 1.93 0.0117 261RLM1_YPD htz1 Meneghini03 1.93 0.0117 51SKN7_YPD Drpd3 Keogh05 1.93 0.0117 55SUT1_YPD WT_N69S Chitikila_02 -1.93 0.0117 63SWI6_YPD sas3D_taf1-ts2Durant06 1.93 0.0117 143DAL82_RAPA MOT1-14 Dasgupta02 1.93 0.0117 56HSF1_H2O2Hi RPD3_haploid Hughes00 -1.93 0.0117 123MSN4_H2O2Hisir4 Orlandi04 -1.93 0.0117 54MBP1_H2O2LoDT_N69S Chitikila_02 -1.93 0.0117 52FKH1_YPD 0.1%_MMS Attikum04 -1.93 0.0117 116FKH2_YPD sap30_del Bernstein_00_affydeletions1.93 0.0117 116HAP4_YPD MED2_haploid Hughes00 1.93 0.0117 67MGA1_YPD sap30_del Bernstein_00_affydeletions-1.93 0.0117 60PHD1_YPD swi1_minimal_medium_experimentSudarsanam00 1.92 0.0118 67SWI6_YPD gcn5D Durant06 -1.92 0.0118 129STE12_Alpha rpd3 Fazzio01 -1.92 0.0118 110DIG1_BUT14 WT_TAF1_SPT3Huisinga04 1.92 0.0118 63PHD1_BUT90 snf2_rich_medium_experimentSudarsanam00 1.92 0.0118 106SKN7_YPD SWR1 Krogan04 1.92 0.0119 60SKN7_YPD gcn5D_taf1-ts2Durant06 1.92 0.0119 60SUT1_YPD hat1_vs.YPH250Rosaleny05 -1.92 0.0119 61AFT2_H2O2Hi spt10 Eriksson05 1.92 0.0119 58NRG1_H2O2HiRpd3_del Bernstein02 1.92 0.0119 123SKN7_H2O2HiDT_Null Chitikila_02 1.92 0.0119 92PHD1_BUT90 RPD3_haploid Hughes00 -1.92 0.0119 106SUT1_YPD ume6 Fazzio01 -1.92 0.012 69SWI6_YPD ZDS1 Hughes00 1.92 0.012 150GCN4_RAPA isw2 Fazzio01 1.92 0.012 155YAP7_H2O2Hi WT_F182V Chitikila_02 1.92 0.012 119XBP1_H2O2Lo swi1_rich_medium_experimentSudarsanam00 1.92 0.012 68ASH1_BUT14 ISW1 Hughes00 1.92 0.012 50GCN4_YPD UBP8 Hughes00 1.92 0.012 75ABF1_YPD TAF2 Mnaimneh_04 1.91 0.0121 267

STE12_YPD DT_N69S Chitikila_02 -1.91 0.0121 40YAP6_YPD swi1_minimal_medium_experimentSudarsanam00 -1.91 0.0121 91YAP6_YPD gcn5D_taf1-ts2Durant06 -1.91 0.0121 80MBP1_H2O2Hi elp3D_taf1-ts2Durant06 1.91 0.0121 103NRG1_H2O2Hielp3D_taf1-ts2Durant06 1.91 0.0121 92RIM101_H2O2Lotaf1-ts2_SPT3 Huisinga04 -1.91 0.0121 52SKN7_H2O2Lohpa2D Durant06 -1.91 0.0121 139MCM1_Alpha arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.91 0.0121 90SOK2_BUT14 hat1D_taf1-ts2Durant06 1.91 0.0121 54STE12_BUT14 rpd3_c.i. Fazzio01 -1.91 0.0121 127MGA1_YPD hht2_K49141823GMartin04 -1.91 0.0121 48NDD1_YPD taf1-ts2 Durant06 1.91 0.0121 83SUM1_YPD hht2_K914182327GMartin04 1.91 0.0122 25SUT1_YPD ubp10 Orlandi04 1.91 0.0122 38SUT1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.91 0.0122 50SUT1_YPD ARD1 Hughes00 -1.91 0.0122 69RTG3_RAPA spt10 Eriksson05 -1.91 0.0122 52RCS1_H2O2Hi spt10 Eriksson05 1.91 0.0122 51CIN5_H2O2Lo spt3_E240K Huisinga04 -1.91 0.0122 111RIM101_H2O2Loesa1-414_taf1-ts2Durant06 1.91 0.0122 41SOK2_BUT14 RAD6_haploid Hughes00 1.91 0.0122 71STE12_BUT14 Rpd3_del Bernstein02 -1.91 0.0122 126PHD1_BUT90 WT_V161E Chitikila_02 -1.91 0.0122 99HAP1_YPD hat1D_taf1-ts2Durant06 1.91 0.0122 127MCM1_YPD isw2_sin3 Fazzio01 1.91 0.0122 73YAP6_YPD MED2_haploid Hughes00 -1.91 0.0123 90GCR2_SM sir2 Meneghini03 1.91 0.0123 53RTG3_RAPA spt3_E240K Huisinga04 1.91 0.0123 47DAL82_RAPA EAF7 Krogan04 1.9 0.0124 51MSN2_H2O2Hihtz1_hmr Meneghini03 1.9 0.0124 78FKH2_YPD YNG2 Krogan04 1.9 0.0124 118MCM1_YPD 0.1%_MMS Attikum04 -1.9 0.0124 60ABF1_YPD HAT2 Hughes00 -1.9 0.0125 264PHO4_YPD ume6_del Bernstein_00_affydeletions-1.9 0.0125 68PHO4_YPD Dsin3 Keogh05 1.9 0.0125 64SWI5_YPD spt3_E240K Huisinga04 -1.9 0.0125 91GCN4_SM htz1_del Mizuguch04 1.9 0.0125 188MBP1_H2O2Lohda1_del Bernstein_00_affydeletions-1.9 0.0125 54PUT3_H2O2Lo TUP1_haploid Hughes00 1.9 0.0125 88RPN4_H2O2LoYNG2 Krogan04 1.9 0.0125 98XBP1_H2O2Lo 0.1%_MMS Attikum04 -1.9 0.0125 42ROX1_YPD hda1_del Bernstein_00_affydeletions1.89 0.0126 54MBP1_H2O2Hihtz1_hmr Meneghini03 1.89 0.0126 131YAP7_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 1.89 0.0126 125PHD1_YPD snf2_minimal_medium_experimentSudarsanam00 1.89 0.0127 67SWI5_YPD htz1 Meneghini03 1.89 0.0127 100SKN7_H2O2Hi rpd3_del Sabet04 -1.89 0.0127 91RCS1_H2O2Losin3_del Bernstein_00_affydeletions1.89 0.0127 247SKN7_H2O2Lohat1_vs.YPH250Rosaleny05 1.89 0.0127 177STE12_Alpha sas3D Durant06 -1.89 0.0127 84RTG3_RAPA TAF2 Mnaimneh_04 -1.89 0.0128 52MBP1_H2O2HiDT_WT Chitikila_02 -1.89 0.0128 126REB1_H2O2Hi spt3_E240K Huisinga04 1.89 0.0128 55

ACE2_YPD DT_V161E Chitikila_02 -1.89 0.0128 75NRG1_YPD ume6 Fazzio01 1.89 0.0128 70GLN3_RAPA sas3D_taf1-ts2Durant06 1.88 0.0129 60UME6_H2O2HiTUP1_haploid Hughes00 1.88 0.0129 100CIN5_H2O2Lo rpd3 Fazzio01 -1.88 0.0129 125SKN7_YPD rpd3 Fazzio01 -1.88 0.013 63SKN7_YPD Drxt1 Keogh05 -1.88 0.013 65SUT1_YPD DT_V161E Chitikila_02 -1.88 0.013 66FKH2_H2O2Hi WT_V161R_K Chitikila_02 -1.88 0.013 94MBP1_H2O2Loisw2_c.i. Fazzio01 1.88 0.013 54SKN7_H2O2Loswr1 Meneghini03 1.88 0.013 150STE12_Alpha hht2_K49141823GMartin04 -1.88 0.013 90SOK2_BUT14 sin3 Fazzio01 -1.88 0.013 71STE12_BUT90 Set1_del Bernstein02 -1.88 0.013 76SWI5_YPD Drpd3 Keogh05 1.88 0.0131 93YAP6_YPD ume6_del Bernstein_00_affydeletions1.88 0.0131 79CIN5_YPD hat1D_taf1-ts2Durant06 1.88 0.0131 119GLN3_RAPA swi1_rich_medium_experimentSudarsanam00 1.88 0.0131 67AFT2_H2O2Hi 0.1%_MMS Attikum04 1.88 0.0131 46FKH2_H2O2Hi WT_V71R Chitikila_02 -1.88 0.0131 94DIG1_Alpha isw2_c.i._rpd3_c.i.Fazzio01 -1.88 0.0131 59DIG1_BUT14 SPT8 Ingvarsdottir05 -1.88 0.0131 59STE12_BUT90 WT_N69S Chitikila_02 -1.88 0.0131 67SKN7_YPD DM_vs._YPH250Rosaleny05 1.87 0.0132 61STE12_YPD RPD3_haploid Hughes00 -1.87 0.0132 52SUT1_YPD DT_V161R_L Chitikila_02 1.87 0.0132 65SWI5_YPD TAF2 Mnaimneh_04 1.87 0.0132 102RCS1_H2O2LoWT_V161E Chitikila_02 1.87 0.0132 235STE12_BUT90 rsc3-2 Angus-Hill_01 1.87 0.0132 71NDD1_YPD WT_V161E Chitikila_02 -1.87 0.0132 82ABF1_YPD ARP4 Mnaimneh_04 -1.87 0.0133 267YAP6_YPD hat1D Durant06 -1.87 0.0133 62DAL82_RAPA Drco1 Keogh05 -1.87 0.0133 53RCS1_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 1.87 0.0133 35GLN3_RAPA Set1_del Bernstein02 1.87 0.0134 67MSN4_RAPA Ddep1 Keogh05 -1.87 0.0134 49HAP4_YPD Set1_del Bernstein02 1.87 0.0134 67CIN5_YPD snf2_rich_medium_experimentSudarsanam00 1.86 0.0135 149GLN3_RAPA sir2 Meneghini03 1.86 0.0135 65REB1_H2O2Hi htz1_hmr Meneghini03 -1.86 0.0135 56PHD1_BUT90 hht2K9131823GMartin04 1.86 0.0135 79GCN4_YPD DT_V161R_L Chitikila_02 -1.86 0.0135 69TYE7_YPD sir2 Meneghini03 1.86 0.0136 54FKH2_H2O2Hi WT_N69S Chitikila_02 -1.86 0.0136 88MSN2_H2O2Hisnf2_minimal_medium_experimentSudarsanam00 1.86 0.0136 78SKN7_H2O2Hi gcn5_KQL Huisinga04 -1.86 0.0136 81AFT2_H2O2Lo DT_N69S Chitikila_02 -1.86 0.0136 94STE12_YPD DT_V161E Chitikila_02 -1.86 0.0137 46FKH2_H2O2Hi delta_ssd1 Kaeberlein04 1.86 0.0137 105RCS1_H2O2LoDT_N69S Chitikila_02 1.86 0.0137 230FKH1_YPD hht2K9131823GMartin04 1.86 0.0137 121SUM1_YPD elp3D Durant06 -1.86 0.0138 40SUM1_YPD WT_V161R_L Chitikila_02 1.86 0.0138 55

MSN2_H2O2HiDeaf3 Keogh05 1.86 0.0138 70MSN4_H2O2HiSIR3 Hughes00 1.86 0.0138 69AFT2_H2O2Lo SIR3 Hughes00 1.86 0.0138 98SOK2_BUT14 WT_V161R_L Chitikila_02 -1.86 0.0138 70ROX1_YPD Dsds3 Keogh05 -1.85 0.0139 63MSN4_H2O2HiVID21 Krogan04 1.85 0.0139 63YAP7_H2O2Hi esa1-414 Durant06 1.85 0.0139 129PUT3_H2O2Lo BUR6 Geisberg_01 1.85 0.0139 85PHD1_BUT90 YNG2 Krogan04 1.85 0.0139 101HAP1_YPD rpd3_H4KQ_v_H4KQSabet04 -1.85 0.0139 137NDD1_YPD isw2_sin3_vs._sin3Fazzio01 -1.85 0.0139 80REB1_YPD hos2_del Bernstein_00_affydeletions1.85 0.014 138SWI6_YPD SPT3 Ingvarsdottir05 1.85 0.014 141YAP1_YPD snf2_minimal_medium_experimentSudarsanam00 1.85 0.014 71HSF1_H2O2Hi ume6_del Bernstein_00_affydeletions1.85 0.014 119MSN4_H2O2HiH3KQ Sabet04 1.85 0.014 65PUT3_H2O2Lo Hda1_del Bernstein02 1.85 0.014 88SOK2_BUT14 hht2_K49141823GMartin04 1.85 0.014 49RTG3_RAPA SWD2 Mnaimneh_04 1.85 0.0141 52MSN4_H2O2HiRAD6_haploid Hughes00 1.85 0.0141 69YAP6_H2O2Hi hht2K9131823GMartin04 -1.85 0.0141 48DAL81_RAPA taf1-ts2_spt3_E240KHuisinga04 1.84 0.0142 86REB1_H2O2Hi WT_V71R Chitikila_02 1.84 0.0142 53DIG1_Alpha Ddep1 Keogh05 -1.84 0.0142 53FKH1_YPD delta_ssd1 Kaeberlein04 1.84 0.0142 142HAP4_YPD H3_1-28 Sabet04 1.84 0.0142 62NRG1_YPD rsc3-2 Angus-Hill_01 1.84 0.0142 70ABF1_YPD H3KQ Sabet04 -1.84 0.0143 261PHD1_YPD snf2_rich_medium_experimentSudarsanam00 1.84 0.0143 67FKH2_H2O2Hi UBP8 Hughes00 -1.84 0.0143 106FKH2_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 -1.84 0.0143 91MSN2_H2O2HiSIN3 Hughes00 1.84 0.0143 77RCS1_H2O2LoDume1 Keogh05 1.84 0.0143 238SKN7_YPD WT_V161R_K Chitikila_02 -1.84 0.0144 66CIN5_YPD taf1-ts2_SPT3 Huisinga04 -1.84 0.0144 143GLN3_RAPA HAT2 Hughes00 -1.84 0.0144 68MSN4_RAPA Dsap30 Keogh05 -1.84 0.0144 50HSF1_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 1.84 0.0144 124MBP1_H2O2HiH4_2-26 Sabet04 -1.84 0.0144 129SKN7_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 -1.84 0.0144 95AFT2_H2O2Lo DT_WT Chitikila_02 -1.84 0.0144 98YAP6_H2O2Lo gcn5 Huisinga04 1.84 0.0144 53YAP7_H2O2Lo gcn5 Huisinga04 1.84 0.0144 146STE12_BUT90 sir4 Orlandi04 -1.84 0.0144 63HAP1_YPD DT_V161R_K Chitikila_02 -1.84 0.0144 139MBP1_YPD DM_vs._YPH250Rosaleny05 1.84 0.0144 124MGA1_YPD H3KQ Sabet04 -1.84 0.0144 61ABF1_YPD MED2_haploid Hughes00 -1.83 0.0145 266STE12_YPD snf2_minimal_medium_experimentSudarsanam00 -1.83 0.0145 52GCN4_SM SWR1 Krogan04 1.83 0.0145 171RTG3_RAPA HDA1 Hughes00 1.83 0.0145 52YAP7_H2O2Lo hht2_K49141823GMartin04 1.83 0.0145 120ABF1_YPD hht2_K4G Martin04 1.83 0.0146 235

SKN7_YPD isw2_rpd3_vs._rpd3Fazzio01 1.83 0.0146 63SWI4_YPD delta_ssd1 Kaeberlein04 1.83 0.0146 153CBF1_SM ino80 Attikum04 -1.83 0.0146 231CBF1_SM DT_N69S Chitikila_02 1.83 0.0146 253GCN4_SM UBP8 Hughes00 1.83 0.0146 188GLN3_RAPA taf1-ts2_gcn5 Huisinga04 1.83 0.0146 65NRG1_H2O2HiMED2_haploid Hughes00 -1.83 0.0146 125RCS1_H2O2Hi SWD2 Mnaimneh_04 1.83 0.0146 52SKN7_H2O2Lorpd3 Fazzio01 -1.83 0.0146 181RLM1_YPD ino80_del Mizuguch04 1.83 0.0147 54HSF1_H2O2LoIES6 Hughes00 1.83 0.0147 100PUT3_H2O2Lo hht2_K27G Martin04 1.83 0.0147 68MCM1_Alpha SWC6_(VPS71)Krogan04 1.83 0.0147 93STE12_BUT14 gcn5D Durant06 -1.83 0.0147 110STE12_BUT90 WT_N69R Chitikila_02 -1.83 0.0147 70YAP6_H2O2Hi snf2_rich_medium_experimentSudarsanam00 1.82 0.0148 79PHD1_BUT90 rpd3_del Sabet04 -1.82 0.0148 96FKH2_YPD EAF7 Krogan04 1.82 0.0148 112CIN5_YPD hht2_K49141823GMartin04 1.82 0.0149 114GCN4_SM rpd3 Fazzio01 1.82 0.0149 183MSN4_H2O2Hiubp10 Orlandi04 1.82 0.0149 50PHD1_BUT90 gcn5_KQL Huisinga04 1.82 0.0149 91FKH2_YPD hht2_K27G Martin04 1.82 0.0149 100PHD1_YPD UBP8 Hughes00 1.82 0.015 67SUM1_YPD swr1_del Mizuguch04 1.82 0.015 58SWI4_YPD RAD6_haploid Hughes00 -1.82 0.015 155SWI5_YPD htz1_sir2 Meneghini03 1.82 0.015 100UME6_YPD sin3_del Bernstein_00_affydeletions1.82 0.015 123CBF1_SM WT_N69R Chitikila_02 -1.82 0.015 249STP1_SM spt10 Eriksson05 -1.82 0.015 68GCN4_RAPA isw2_sin3_vs._sin3Fazzio01 -1.82 0.015 155RCS1_H2O2Hi SSD1-V Kaeberlein04 1.82 0.015 52PUT3_H2O2Lo rpd3_del Sabet04 -1.82 0.015 85NDD1_YPD Drpd3 Keogh05 1.82 0.015 80NRG1_YPD TAF2 Mnaimneh_04 -1.82 0.015 72ABF1_YPD sin3_del Bernstein_00_affydeletions1.82 0.0151 255PHD1_YPD DT_Null Chitikila_02 -1.82 0.0151 66CBF1_SM ISW1_ISW2 Hughes00 -1.82 0.0151 278GCR2_SM hht2_K49141823GMartin04 -1.82 0.0151 45NRG1_H2O2Higcn5D Durant06 1.82 0.0151 102YAP7_H2O2Hi Ddep1 Keogh05 1.82 0.0151 127HSF1_H2O2LoSPT8 Ingvarsdottir05 1.82 0.0151 93RCS1_H2O2Lorsc3-2 Angus-Hill_01 1.82 0.0151 249YAP6_H2O2Lo sas3D_taf1-ts2Durant06 -1.82 0.0151 46ASH1_BUT14 spt10_del Xu05 1.82 0.0151 48PHD1_YPD RAD6_haploid Hughes00 1.81 0.0152 67STE12_YPD YAF9 Krogan04 1.81 0.0152 51SUT1_YPD spt10_del Xu05 -1.81 0.0152 68RIM101_H2O2Lotaf1-ts2 Durant06 -1.81 0.0152 53YAP6_H2O2Lo DT_V161E Chitikila_02 -1.81 0.0152 53ASH1_BUT14 WT_N69S Chitikila_02 -1.81 0.0152 47PHD1_BUT90 ino80_del Mizuguch04 1.81 0.0152 106SUM1_YPD DT_N69S Chitikila_02 -1.81 0.0153 44

SWI5_YPD gcn5 Huisinga04 1.81 0.0153 93CBF1_SM EPL1 Mnaimneh_04 1.81 0.0153 278RIM101_H2O2LoUBP8 Hughes00 1.81 0.0153 53RPN4_H2O2LoRPD3_haploid Hughes00 1.81 0.0153 98RPN4_H2O2Lohtz1_hmr Meneghini03 1.81 0.0153 98DIG1_Alpha taf1-ts2_SPT3 Huisinga04 1.81 0.0153 55FKH2_YPD ARP4 Mnaimneh_04 1.81 0.0153 121SUT1_YPD sap30_del Bernstein_00_affydeletions-1.81 0.0154 61DAL82_SM SWR1 Krogan04 1.81 0.0154 50GCN4_RAPA rpd3_del Sabet04 1.81 0.0154 157AFT2_H2O2Lo UBP8 Ingvarsdottir05 1.81 0.0154 87RCS1_H2O2LoDT_V71E Chitikila_02 1.81 0.0154 244STE12_BUT14 htz1_sir2 Meneghini03 -1.81 0.0154 126NRG1_YPD DT_N69S Chitikila_02 -1.81 0.0154 60PHD1_YPD gcn5_KQL Huisinga04 1.8 0.0155 57YAP1_YPD gcn5 Huisinga04 1.8 0.0155 69GLN3_RAPA DT_WT Chitikila_02 -1.8 0.0155 65AFT2_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 1.8 0.0155 46MBP1_H2O2Hi ISW1 Hughes00 1.8 0.0155 133REB1_H2O2Hi WT_V161R_K Chitikila_02 1.8 0.0155 51RCS1_H2O2Losas3D Durant06 1.8 0.0155 211SKN7_H2O2Lotaf1-ts2_spt3 Huisinga04 -1.8 0.0155 172XBP1_H2O2Lo DT_N69R Chitikila_02 1.8 0.0155 63CBF1_SM hht2_K4G Martin04 1.8 0.0156 225GCN4_RAPA MED2_haploid Hughes00 -1.8 0.0156 157AFT2_H2O2Hi WT_V161R_L Chitikila_02 -1.8 0.0156 58RIM101_H2O2LoDT_V71R Chitikila_02 1.8 0.0156 51MCM1_Alpha SWR1 Krogan04 1.8 0.0156 102MCM1_YPD ARP4 Mnaimneh_04 1.8 0.0156 77ROX1_YPD RPD3_haploid Hughes00 -1.8 0.0157 66AFT2_H2O2Lo PCH1 Hughes00 1.8 0.0157 96MBP1_H2O2LoIES6 Hughes00 -1.8 0.0157 58MCM1_Alpha Dsds3 Keogh05 1.8 0.0157 96NRG1_H2O2HiISW2 Hughes00 -1.8 0.0158 126MCM1_Alpha htz1_del Mizuguch04 1.8 0.0158 105STE12_BUT14 esa1-414_taf1-ts2Durant06 1.8 0.0158 122ACE2_YPD DT_N69S Chitikila_02 -1.8 0.0158 72HAP4_YPD hat1_vs.YPH250Rosaleny05 1.8 0.0158 62PHO4_YPD hos2_del Bernstein_00_affydeletions-1.79 0.0159 68REB1_YPD hat1_vs.YPH250Rosaleny05 1.79 0.0159 140GCR2_SM TAF2 Mnaimneh_04 1.79 0.0159 53NRG1_H2O2HiEAF7 Krogan04 1.79 0.0159 117NRG1_H2O2Hihat1D_taf1-ts2Durant06 1.79 0.0159 97RPN4_H2O2Lohtz1_del Mizuguch04 1.79 0.0159 100FKH2_YPD snf2_minimal_medium_experimentSudarsanam00 -1.79 0.0159 120MBP1_YPD htz1_del Mizuguch04 1.79 0.0159 130NRG1_YPD spt10 Eriksson05 1.79 0.0159 60OAF1_YPD MOT1-14 Dasgupta02 1.79 0.0159 58ABF1_YPD ino80 Attikum04 -1.79 0.016 229STE12_YPD taf1-ts2 Durant06 1.79 0.016 49DAL82_SM EPL1 Mnaimneh_04 1.79 0.016 55HSF1_H2O2Lo0.1%_MMS Attikum04 1.79 0.016 88RCS1_H2O2LoWT_V71E Chitikila_02 1.79 0.016 219

YAP6_H2O2Lo hat1D_taf1-ts2Durant06 -1.79 0.016 44STE12_BUT14 WT_TAF1_SPT3Huisinga04 1.79 0.016 123MBP1_YPD HAT2 Hughes00 1.79 0.016 128CBF1_SM gcn5D_taf1-ts2Durant06 1.79 0.0161 256DAL82_SM SIR2 Hughes00 1.79 0.0161 54UME6_H2O2Hisas3D_taf1-ts2Durant06 1.79 0.0161 89HSF1_H2O2Lo ino80_+_0.1%_MMS_vs._ino80Attikum04 1.79 0.0161 85RPN4_H2O2Losin3_del Bernstein_00_affydeletions1.79 0.0161 98STE12_BUT14 swi1_minimal_medium_experimentSudarsanam00 -1.79 0.0161 128ACE2_YPD sas3D_taf1-ts2Durant06 1.79 0.0161 69NDD1_YPD TUP1_haploid Hughes00 -1.79 0.0161 85NDD1_YPD YNG2 Mnaimneh_04 1.79 0.0161 85ABF1_YPD WT_N69S Chitikila_02 1.79 0.0162 237STE12_YPD _SWC2_(VPS72)Krogan04 1.79 0.0162 52GLN3_RAPA ume6_del Bernstein_00_affydeletions1.79 0.0162 64UME6_H2O2HiH4KQ Sabet04 1.79 0.0162 99YAP6_H2O2Lo htz1_sir2 Meneghini03 -1.79 0.0162 58FKH1_YPD rpd3_H4KQ_v_H4KQSabet04 1.79 0.0162 137DAL82_RAPA isw2_rpd3_vs._rpd3Fazzio01 -1.78 0.0163 54RCS1_H2O2Hi ino80 Attikum04 1.78 0.0163 34UME6_H2O2Hihpa2D Durant06 -1.78 0.0163 83STE12_BUT14 esa1-414 Durant06 1.78 0.0163 117REB1_H2O2Hi swi1_rich_medium_experimentSudarsanam00 -1.78 0.0164 58STE12_BUT90 Dume1 Keogh05 -1.78 0.0164 75ACE2_YPD HIR2 Hughes00 1.78 0.0164 79REB1_YPD spt10_del Xu05 1.78 0.0165 138SKN7_YPD hat1D_taf1-ts2Durant06 1.78 0.0165 53DAL81_RAPA arp8 Attikum04 -1.78 0.0165 74NRG1_H2O2Hiisw2_ume6 Fazzio01 -1.78 0.0165 123RPN4_H2O2LoDT_V71R Chitikila_02 -1.78 0.0165 97YAP6_H2O2Lo htz1 Meneghini03 -1.78 0.0165 57SUT1_YPD RPD3_haploid Hughes00 -1.77 0.0166 68DAL82_RAPA DT_WT Chitikila_02 -1.77 0.0166 53SKN7_H2O2Lospt10 Eriksson05 -1.77 0.0166 186STE12_BUT14 rpd3 Fazzio01 -1.77 0.0166 127UME6_YPD YAF9 Krogan04 1.77 0.0167 119CIN5_H2O2Lo ume6 Fazzio01 1.77 0.0167 124PHD1_BUT90 WT_N69S Chitikila_02 -1.77 0.0167 98HAP1_YPD DT_WT Chitikila_02 -1.77 0.0167 139SUM1_YPD DT_WT Chitikila_02 -1.77 0.0168 54CBF1_SM spt10 Eriksson05 -1.77 0.0168 276CBF1_SM ARP4 Mnaimneh_04 1.77 0.0168 279STP1_SM SIR4 Hughes00 1.77 0.0168 67MSN2_H2O2HiHTZ1 Krogan04 1.77 0.0168 74SOK2_BUT14 Dpho23 Keogh05 -1.77 0.0168 69MGA1_YPD gcn5_KQL Huisinga04 -1.77 0.0168 53NRG1_YPD rpd3_H3dN_v_H3dNSabet04 1.77 0.0168 60YAP6_YPD hht2_K49141823GMartin04 -1.77 0.0169 64CIN5_YPD swi1_rich_medium_experimentSudarsanam00 1.77 0.0169 150MBP1_H2O2Hi ISW2 Hughes00 -1.77 0.0169 133YAP6_H2O2Hi gcn5D_taf1-ts2Durant06 -1.77 0.0169 70YAP7_H2O2Hi taf1-ts2_gcn5 Huisinga04 1.77 0.0169 138AFT2_H2O2Lo SPT3 Ingvarsdottir05 1.77 0.0169 80

YAP6_H2O2Lo taf1-ts2_GCN5Huisinga04 -1.77 0.0169 52NRG1_YPD esa1-414 Durant06 -1.77 0.0169 61RLM1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -1.76 0.017 54SKN7_YPD spt3 Huisinga04 -1.76 0.017 63SUT1_YPD IES6 Hughes00 1.76 0.017 69YAP6_YPD SPT8 Ingvarsdottir05 -1.76 0.017 83DIG1_Alpha hpa2D Durant06 -1.76 0.017 43ACE2_YPD SWC6_(VPS71)Krogan04 1.76 0.017 66PHD1_YPD ISW1_ISW2 Hughes00 1.76 0.0171 67ROX1_YPD SIR1 Hughes00 1.76 0.0171 66SUT1_YPD rpd3_c.i. Fazzio01 -1.76 0.0171 69SWI4_YPD SPT8 Ingvarsdottir05 -1.76 0.0171 142DAL82_SM Dsap30 Keogh05 -1.76 0.0171 52MCM1_Alpha H3KQ Sabet04 -1.76 0.0171 103UME6_YPD RSC8 Mnaimneh_04 1.76 0.0172 131GLN3_RAPA isw2_rpd3 Fazzio01 -1.76 0.0172 67SKN7_H2O2HiHST3 Hughes00 1.76 0.0172 97SKN7_H2O2HiWT_F182V Chitikila_02 1.76 0.0172 81XBP1_H2O2Lo RPD3_haploid Hughes00 -1.76 0.0172 67YAP6_H2O2Lo Drxt1 Keogh05 -1.76 0.0172 58DIG1_Alpha elp3D Durant06 -1.76 0.0172 43NRG1_YPD hht2_K4914182327GMartin04 1.76 0.0172 34DAL81_RAPA isw2_ume6 Fazzio01 -1.76 0.0173 91AFT2_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 1.76 0.0173 61MSN2_H2O2Hihht2_K4G Martin04 1.76 0.0173 60SOK2_BUT14 swi1_minimal_medium_experimentSudarsanam00 1.76 0.0173 72SOK2_BUT14 MOT1-14 Dasgupta02 1.76 0.0173 72STE12_BUT90 spt3 Huisinga04 -1.76 0.0173 73SWI6_YPD WT_TAF1_GCN5Huisinga04 -1.75 0.0174 152CIN5_YPD WT_V161R_K Chitikila_02 -1.75 0.0174 140XBP1_H2O2Lo WT_V161R_K Chitikila_02 1.75 0.0174 59HAP4_YPD gcn5D Durant06 1.75 0.0174 58SUT1_YPD Drxt2 Keogh05 -1.75 0.0175 66UME6_H2O2HiMOT1-14 Dasgupta02 1.75 0.0175 101DIG1_BUT14 WT_TAF1_GCN5Huisinga04 1.75 0.0175 63MBP1_YPD Rpd3_del Bernstein02 1.75 0.0175 128HSF1_H2O2Hi WT_Null_K Chitikila_02 -1.75 0.0176 121PUT3_H2O2Lo isw2_sin3 Fazzio01 -1.75 0.0176 86STE12_BUT14 ino80 Attikum04 -1.75 0.0176 105SWI6_YPD Ddep1 Keogh05 1.75 0.0177 146MSN4_H2O2HiUBP8 Ingvarsdottir05 1.75 0.0177 65RCS1_H2O2Hi Dsin3 Keogh05 1.75 0.0177 43MSN4_RAPA htz1 Meneghini03 1.74 0.0178 50FKH2_H2O2Hi SWD2 Mnaimneh_04 1.74 0.0178 106MBP1_H2O2HiWT_V71R Chitikila_02 -1.74 0.0178 120ACE2_YPD ubp10 Orlandi04 1.74 0.0178 59ACE2_YPD isw2_ume6 Fazzio01 -1.74 0.0178 74ABF1_YPD ISW1_ISW2 Hughes00 -1.74 0.0179 263PHD1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -1.74 0.0179 45STE12_YPD Dpho23 Keogh05 -1.74 0.0179 54MSN2_H2O2Hitaf1-ts2_spt3 Huisinga04 1.74 0.0179 77UME6_H2O2Hisin3_del Bernstein_00_affydeletions1.74 0.0179 97SWI5_YPD taf1-ts2_SPT3 Huisinga04 1.74 0.018 93

FKH2_H2O2Hi MED2_haploid Hughes00 -1.74 0.018 106YAP7_H2O2Hi gcn5 Huisinga04 1.74 0.018 138YAP7_H2O2Lo MOT1-14 Dasgupta02 1.74 0.018 147STE12_Alpha Dsds3 Keogh05 -1.74 0.018 112FKH1_YPD gcn5 Huisinga04 -1.74 0.018 134ROX1_YPD taf1-ts2_spt3_E240KHuisinga04 -1.74 0.0181 60YAP1_YPD Hda1_del Bernstein02 1.74 0.0181 71MBP1_H2O2HiSSD1-V Kaeberlein04 1.74 0.0181 130ASH1_BUT14 TAF2 Mnaimneh_04 1.74 0.0181 50REB1_YPD swi1_rich_medium_experimentSudarsanam00 -1.73 0.0182 143SWI4_YPD isw2_sin3 Fazzio01 1.73 0.0182 152STP1_SM snf2_rich_medium_experimentSudarsanam00 1.73 0.0182 67SKN7_H2O2LoSet1_del Bernstein02 1.73 0.0182 183ASH1_BUT14 Rpd3_del Bernstein02 1.73 0.0182 49SOK2_BUT14 WT_V161R_K Chitikila_02 -1.73 0.0182 67TYE7_YPD WT_F182V Chitikila_02 1.73 0.0183 49YAP6_YPD H4KQ Sabet04 1.73 0.0183 82CIN5_H2O2Hi MOT1-14 Dasgupta02 1.73 0.0183 80REB1_H2O2Hi ARD1 Hughes00 1.73 0.0183 59PUT3_H2O2Lo hat2_vs._YPH250Rosaleny05 1.73 0.0183 86PHD1_BUT90 ISW1_ISW2 Hughes00 1.73 0.0183 105YAP6_H2O2Hi taf1-ts2 Durant06 -1.73 0.0184 79HAP4_YPD gcn5D_taf1-ts2Durant06 1.73 0.0184 62MGA1_YPD H3_1-28 Sabet04 -1.73 0.0184 61HSF1_H2O2Hi elp3D_taf1-ts2Durant06 1.73 0.0185 100NRG1_H2O2Hiisw2_c.i._rpd3_c.i.Fazzio01 1.73 0.0185 123RIM101_H2O2Loisw2_ume6 Fazzio01 1.73 0.0185 52XBP1_H2O2Lo UBP8 Hughes00 1.73 0.0185 66REB1_YPD hht2_K4914182327GMartin04 1.73 0.0186 129STE12_YPD htz1_sir2 Meneghini03 -1.73 0.0186 52RIM101_H2O2LoRpd3_del Bernstein02 -1.73 0.0186 53TYE7_YPD delta_ssd1 Kaeberlein04 1.72 0.0187 55HSF1_H2O2Hi WT_Null_L Chitikila_02 -1.72 0.0187 115MSN4_H2O2HiSIN3 Hughes00 1.72 0.0187 69REB1_H2O2Hi ARP4 Mnaimneh_04 -1.72 0.0187 59HSF1_H2O2LoEAF7 Krogan04 1.72 0.0187 93PHD1_BUT90 hos2_del Bernstein_00_affydeletions-1.72 0.0187 88MBP1_YPD VID21 Krogan04 1.72 0.0187 122SUM1_YPD WT Durant06 -1.72 0.0188 53MBP1_H2O2HiDM_vs._YPH250Rosaleny05 1.72 0.0188 121ROX1_YPD WT_V161R_K Chitikila_02 1.72 0.0189 67YAP6_YPD DT_WT Chitikila_02 -1.72 0.0189 82CBF1_SM WT_V161R_L Chitikila_02 -1.72 0.0189 267GLN3_RAPA ume6 Fazzio01 1.72 0.0189 67YAP6_H2O2Hi DT_V161R_L Chitikila_02 1.72 0.0189 74CIN5_H2O2Lo ino80_del Mizuguch04 -1.72 0.0189 127MBP1_H2O2Logcn5D_taf1-ts2Durant06 -1.72 0.0189 54AFT2_H2O2Hi SSD1-V Kaeberlein04 1.72 0.019 61CIN5_H2O2Hi isw2_sin3 Fazzio01 -1.72 0.019 79PUT3_H2O2Lo 0.1%_MMS Attikum04 1.72 0.019 69YAP6_H2O2Lo spt3_E240K Huisinga04 -1.72 0.019 50SOK2_BUT14 RPD3_haploid Hughes00 -1.72 0.019 72NDD1_YPD sas3D_taf1-ts2Durant06 1.72 0.019 80

SUT1_YPD swr1_del Mizuguch04 -1.71 0.0191 69SWI6_YPD swi1_minimal_medium_experimentSudarsanam00 -1.71 0.0191 153SWI6_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.71 0.0191 127GCN4_SM ino80_del Mizuguch04 1.71 0.0191 188HSF1_H2O2Hi hos3_del Bernstein_00_affydeletions1.71 0.0191 120CIN5_H2O2Lo SPT3 Ingvarsdottir05 -1.71 0.0191 108XBP1_H2O2Lo DT_WT Chitikila_02 -1.71 0.0191 66SWI4_YPD SGF11 Ingvarsdottir05 -1.71 0.0192 134YAP1_YPD PCH1 Hughes00 1.71 0.0192 70GCN4_RAPA rpd3 Fazzio01 1.71 0.0192 155ASH1_BUT14 ARD1 Hughes00 -1.71 0.0192 49NDD1_YPD Deaf3 Keogh05 1.71 0.0192 79AFT2_H2O2Lo WT_WT Chitikila_02 1.71 0.0193 94PUT3_H2O2Lo sap30_del Bernstein_00_affydeletions1.71 0.0193 81SKN7_H2O2LoH4_2-26 Sabet04 1.71 0.0193 177STE12_YPD WT_TAF1_SPT3Huisinga04 1.71 0.0194 49SKN7_H2O2HiBUR6 Geisberg_01 1.71 0.0194 91DIG1_Alpha rpd3_H3dN_v_H3dNSabet04 -1.71 0.0194 56FKH2_H2O2Hi hat1D_taf1-ts2Durant06 1.7 0.0195 86PUT3_H2O2Lo YNG2 Krogan04 1.7 0.0195 82MCM1_Alpha IOC4 Hughes00 1.7 0.0195 105ASH1_BUT14 MOT1-14 Dasgupta02 1.7 0.0195 50MGA1_YPD hht2_K4914182327GMartin04 -1.7 0.0195 49YAP6_YPD hht2_K4G Martin04 -1.7 0.0196 64NRG1_H2O2HiHTZ1 Krogan04 1.7 0.0196 118SOK2_BUT14 arp8 Attikum04 1.7 0.0196 49SUT1_YPD esa1-414 Durant06 1.7 0.0197 57TYE7_YPD isw2_sin3 Fazzio01 -1.7 0.0197 54RCS1_H2O2Hi rpd3_del Sabet04 -1.7 0.0197 50RIM101_H2O2Loubp10sir4 Orlandi04 -1.7 0.0197 24RPN4_H2O2LoRSC8 Mnaimneh_04 1.7 0.0197 100NRG1_YPD VID21 Krogan04 1.7 0.0197 59CBF1_SM HDA1 Hughes00 1.7 0.0198 277CBF1_SM Dsin3 Keogh05 1.7 0.0198 229HSF1_H2O2Hi sir4 Orlandi04 -1.7 0.0198 94NRG1_H2O2Higcn5D_taf1-ts2Durant06 1.7 0.0198 111STE12_Alpha Drxt2 Keogh05 -1.7 0.0198 112ABF1_YPD hat1D Durant06 1.7 0.0199 209SWI4_YPD HAT2 Hughes00 1.7 0.0199 154CIN5_YPD RPD3_haploid Hughes00 -1.7 0.0199 150FKH2_H2O2Hi sin3_del Bernstein_00_affydeletions1.7 0.0199 101RIM101_H2O2Lohtz1_hmr Meneghini03 -1.7 0.0199 52MCM1_Alpha gcn5D_taf1-ts2Durant06 1.7 0.0199 98PHD1_BUT90 RSC8 Mnaimneh_04 1.7 0.0199 106SUT1_YPD SIN3 Hughes00 -1.69 0.02 67GCN4_RAPA DT_N69S Chitikila_02 1.69 0.02 153AFT2_H2O2Hi hat1_vs.YPH250Rosaleny05 1.69 0.02 57AFT2_H2O2Lo ISW1_ISW2 Hughes00 -1.69 0.02 98CIN5_H2O2Lo IES6 Hughes00 -1.69 0.02 125DIG1_Alpha taf1-ts2 Durant06 1.69 0.02 58HAP1_YPD YNG2 Krogan04 1.69 0.02 135MGA1_YPD sir2 Meneghini03 -1.69 0.02 58STE12_YPD DT_V161R_L Chitikila_02 -1.69 0.0201 46

MBP1_H2O2Hi rsc30_null Angus-Hill_01 1.69 0.0201 129MSN2_H2O2HiRPD3_haploid Hughes00 1.69 0.0201 75CIN5_H2O2Lo ISW1_ISW2 Hughes00 1.69 0.0201 126UME6_YPD Hda1_del Bernstein02 1.69 0.0202 129SOK2_BUT14 Dsap30 Keogh05 -1.69 0.0202 71HAP1_YPD taf1-ts2_SPT3 Huisinga04 1.69 0.0202 137MCM1_YPD hat2_vs._YPH250Rosaleny05 -1.69 0.0202 72SUT1_YPD ZDS1 Hughes00 1.69 0.0203 68SWI5_YPD ubp10 Orlandi04 1.69 0.0203 70DAL81_RAPA DT_N69R Chitikila_02 1.69 0.0203 93GCN4_RAPA UBP8 Hughes00 1.69 0.0203 160YAP7_H2O2Hi Drpd3 Keogh05 1.69 0.0203 132XBP1_H2O2Lo hat1D_taf1-ts2Durant06 -1.69 0.0203 47HAP1_YPD hht2_K4G Martin04 1.69 0.0203 119RLM1_YPD isw2_sin3_vs._sin3Fazzio01 -1.69 0.0204 54STE12_YPD SWR1 Krogan04 1.69 0.0204 53GCR2_SM swi1_minimal_medium_experimentSudarsanam00 -1.69 0.0204 54GCN4_RAPA taf1-ts2_gcn5_KQLHuisinga04 1.69 0.0204 149MSN2_H2O2HiUBP8 Ingvarsdottir05 1.69 0.0204 73REB1_H2O2Hi hht2K9131823GMartin04 1.68 0.0205 51MCM1_YPD isw2_c.i._rpd3_c.i.Fazzio01 1.68 0.0205 73NDD1_YPD ubp10sir4 Orlandi04 -1.68 0.0205 69NRG1_YPD SPT3 Ingvarsdottir05 -1.68 0.0205 59XBP1_H2O2Lo taf1-ts2 Durant06 -1.68 0.0206 68YAP7_H2O2Lo WT_F182V Chitikila_02 1.68 0.0206 124PHD1_BUT90 EPL1 Mnaimneh_04 1.68 0.0206 106TYE7_YPD swi1_rich_medium_experimentSudarsanam00 -1.68 0.0207 54MSN2_H2O2HiSSD1-V Kaeberlein04 1.68 0.0207 78SKN7_H2O2LoARD1 Hughes00 -1.68 0.0207 185DIG1_Alpha SWD2 Mnaimneh_04 -1.68 0.0207 60STE12_Alpha sin3 Fazzio01 -1.68 0.0207 112HAP4_YPD taf1-ts2_gcn5_KQLHuisinga04 -1.68 0.0207 60STP1_SM esa1-414_taf1-ts2Durant06 1.68 0.0208 61AFT2_H2O2Hi HIR2 Hughes00 1.68 0.0208 57YAP7_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 -1.68 0.0208 137NRG1_YPD DT_V161R_K Chitikila_02 1.68 0.0208 67GCR2_SM SPT8 Ingvarsdottir05 1.67 0.0209 49GLN3_RAPA rsc30_null Angus-Hill_01 -1.67 0.0209 66CIN5_H2O2Lo UBP8 Hughes00 1.67 0.0209 125HSF1_H2O2LoH3_1-28 Sabet04 -1.67 0.0209 98STE12_Alpha YNG2 Mnaimneh_04 -1.67 0.0209 115ABF1_YPD BUR6 Geisberg_01 -1.67 0.021 258RLM1_YPD spt3_E240K Huisinga04 -1.67 0.021 48STE12_YPD rpd3_H3dN_v_H3dNSabet04 -1.67 0.021 51NRG1_H2O2HiSSD1-V Kaeberlein04 1.67 0.021 123AFT2_H2O2Lo rpd3_H3dN_v_H3dNSabet04 1.67 0.021 91CIN5_H2O2Lo rsc30_null Angus-Hill_01 -1.67 0.021 127YAP7_H2O2Lo ISW1 Hughes00 -1.67 0.021 151HAP1_YPD HAT2 Hughes00 1.67 0.021 139OAF1_YPD DT_V161E Chitikila_02 -1.67 0.021 52SKN7_YPD ume6_del Bernstein_00_affydeletions1.67 0.0211 58SUT1_YPD SIR1 Hughes00 1.67 0.0211 69STP1_SM hht2_K4914182327GMartin04 -1.67 0.0211 53

UME6_H2O2Hirpd3_c.i. Fazzio01 1.67 0.0211 98MBP1_H2O2Lospt10 Eriksson05 1.67 0.0211 57FKH1_YPD swr1 Meneghini03 1.67 0.0211 119STE12_BUT14 WT_F182V Chitikila_02 1.67 0.0211 109GCN4_YPD spt3 Huisinga04 -1.67 0.0211 71NRG1_YPD UBP8 Hughes00 1.67 0.0211 70ABF1_YPD Dpho23 Keogh05 1.67 0.0213 264STE12_YPD swi1_rich_medium_experimentSudarsanam00 -1.67 0.0213 52SWI6_YPD HAT2 Hughes00 1.67 0.0213 151STE12_Alpha taf1-ts2 Durant06 1.67 0.0213 110CIN5_YPD isw2_rpd3 Fazzio01 -1.66 0.0214 148AFT2_H2O2Hi Dsap30 Keogh05 1.66 0.0214 58XBP1_H2O2Lo SIR2 Hughes00 1.66 0.0214 67ACE2_YPD YAF9 Krogan04 1.66 0.0214 73NRG1_YPD H3KQ Sabet04 1.66 0.0214 60MBP1_H2O2Hihtz1_sir2 Meneghini03 1.66 0.0215 130UME6_H2O2Hispt10 Eriksson05 1.66 0.0215 102HSF1_H2O2LoWT_Null_K Chitikila_02 -1.66 0.0215 98GCN4_YPD hat1D_taf1-ts2Durant06 1.66 0.0215 68YAP6_YPD sir2 Meneghini03 1.66 0.0216 90FKH2_H2O2Hi hht2_K49141823GMartin04 1.66 0.0216 90NDD1_YPD sir4 Orlandi04 -1.66 0.0216 68ROX1_YPD ISW1_ISW2 Hughes00 1.66 0.0217 65FKH2_H2O2Hi WT_N69R Chitikila_02 -1.66 0.0217 89UME6_H2O2Hihpa2D_taf1-ts2Durant06 1.66 0.0217 79YAP6_H2O2Hi HDA1 Hughes00 1.66 0.0217 77YAP7_H2O2Hi H4KQ Sabet04 1.66 0.0217 138RCS1_H2O2LoDT_V161E Chitikila_02 1.66 0.0217 236YAP6_H2O2Lo YNG2 Mnaimneh_04 1.66 0.0217 59FKH2_YPD isw2_ume6 Fazzio01 -1.66 0.0217 119STP1_SM swi1_rich_medium_experimentSudarsanam00 1.66 0.0218 67CIN5_H2O2Lo EAF7 Krogan04 -1.66 0.0218 112RIM101_H2O2Losas3D_taf1-ts2Durant06 -1.66 0.0218 45SKN7_H2O2Losin3_del Bernstein_00_affydeletions-1.66 0.0218 165NRG1_H2O2HiRAD6_haploid Hughes00 1.65 0.0219 124CIN5_H2O2Lo isw2_rpd3_vs._rpd3Fazzio01 -1.65 0.0219 124PHD1_BUT90 taf1-ts2 Durant06 1.65 0.0219 104FKH2_YPD hht2_K49141823GMartin04 1.65 0.0219 100MBP1_YPD isw2_rpd3_vs._rpd3Fazzio01 1.65 0.0219 123MGA1_YPD isw2_sin3 Fazzio01 -1.65 0.0219 60FKH2_H2O2Hi EPL1 Mnaimneh_04 1.65 0.022 106MBP1_H2O2HiH3KQ Sabet04 -1.65 0.022 129MSN4_H2O2Hiubp10sir4 Orlandi04 1.65 0.022 55SKN7_H2O2Loisw2_rpd3_vs._rpd3Fazzio01 -1.65 0.022 181MGA1_YPD TAF2 Mnaimneh_04 -1.65 0.022 62REB1_YPD sas3D Durant06 1.65 0.0221 118SUT1_YPD WT_V71R Chitikila_02 -1.65 0.0221 65YAP6_H2O2Hi sas3D_taf1-ts2Durant06 -1.65 0.0221 65NDD1_YPD HIR2 Hughes00 1.65 0.0221 83RTG3_RAPA taf1-ts2 Durant06 1.65 0.0222 51RCS1_H2O2Lorpd3_c.i. Fazzio01 1.65 0.0222 253RPN4_H2O2LoZDS1 Hughes00 1.65 0.0222 98HAP1_YPD htz1_del Mizuguch04 1.65 0.0222 141

MSN2_H2O2HiDdep1 Keogh05 1.65 0.0223 71CIN5_H2O2Lo WT_F182V Chitikila_02 1.65 0.0223 107PHD1_YPD isw2 Fazzio01 1.64 0.0224 66SUT1_YPD taf1-ts2_gcn5 Huisinga04 1.64 0.0224 67CIN5_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 -1.64 0.0224 79FKH1_YPD H4_2-26 Sabet04 -1.64 0.0224 138STE12_BUT14 hht2_K4914182327GMartin04 -1.64 0.0224 111SKN7_YPD htz1_sir2 Meneghini03 1.64 0.0225 66GCR2_SM taf1-ts2_SPT3 Huisinga04 1.64 0.0225 54NRG1_H2O2HiARP4 Mnaimneh_04 1.64 0.0225 126YAP6_H2O2Hi hat1D Durant06 -1.64 0.0225 49MBP1_H2O2LoSAP30 Hughes00 1.64 0.0225 56MBP1_H2O2LoMED2_haploid Hughes00 1.64 0.0225 58STE12_Alpha ino80_del Mizuguch04 -1.64 0.0225 115DIG1_BUT14 HTZ1 Krogan04 1.64 0.0225 61FKH1_YPD Drxt2 Keogh05 1.64 0.0225 136ABF1_YPD elp3D_taf1-ts2Durant06 1.64 0.0226 216CIN5_YPD MED2_haploid Hughes00 -1.64 0.0226 149MBP1_H2O2Hi swr1_del Mizuguch04 1.64 0.0226 131ASH1_BUT14 ino80 Attikum04 1.64 0.0226 31MBP1_H2O2HiYAF9 Krogan04 1.64 0.0227 127REB1_H2O2Hi H4KQ Sabet04 -1.64 0.0227 57YAP6_H2O2Hi HTZ1 Krogan04 -1.64 0.0227 77RIM101_H2O2Lorpd3_H4KQ_v_H4KQSabet04 -1.64 0.0227 44MGA1_YPD WT_V161R_L Chitikila_02 1.64 0.0227 60NDD1_YPD EAF5 Krogan04 1.64 0.0227 76ROX1_YPD gcn5D_taf1-ts2Durant06 -1.64 0.0228 57RCS1_H2O2Hi WT_V71R Chitikila_02 1.64 0.0228 46ASH1_BUT14 taf1-ts2_spt3 Huisinga04 -1.64 0.0228 48DIG1_BUT14 htz1_sir2 Meneghini03 -1.64 0.0228 62MBP1_H2O2HiWT_TAF1_SPT3Huisinga04 -1.64 0.0229 125ACE2_YPD sir2 Meneghini03 1.64 0.0229 80PHO4_YPD isw2_rpd3 Fazzio01 1.63 0.023 71SWI5_YPD WT_V71E Chitikila_02 -1.63 0.023 86YAP7_H2O2Hi SSN6_haploid Hughes00 1.63 0.023 139RIM101_H2O2Loswi1_rich_medium_experimentSudarsanam00 1.63 0.023 54RPN4_H2O2LoIOC4 Hughes00 1.63 0.023 96STE12_Alpha BUR6 Geisberg_01 1.63 0.023 108FKH1_YPD HIR2 Hughes00 -1.63 0.023 140STP1_SM PCH1 Hughes00 1.63 0.0231 65GLN3_RAPA htz1_sir2 Meneghini03 1.63 0.0231 64UME6_H2O2HiWT_Null_K Chitikila_02 1.63 0.0231 95CIN5_H2O2Lo sas3D_taf1-ts2Durant06 1.63 0.0231 109RIM101_H2O2LoMOT1-42 Dasgupta02 1.63 0.0231 54CBF1_SM SPT8 Ingvarsdottir05 1.63 0.0232 248GCR2_SM H4KQ Sabet04 1.63 0.0232 54NRG1_YPD hos2_del Bernstein_00_affydeletions-1.63 0.0232 52SWI6_YPD SPT8 Ingvarsdottir05 -1.63 0.0233 143REB1_H2O2Hi gcn5_KQL Huisinga04 -1.63 0.0233 50NRG1_YPD hht2_K49141823GMartin04 1.63 0.0233 35YAP6_YPD ISW2 Hughes00 -1.62 0.0235 91STE12_Alpha Dume1 Keogh05 -1.62 0.0235 105ACE2_YPD rpd3_H4KQ_v_H4KQSabet04 -1.62 0.0235 77

MBP1_H2O2HiVID21 Krogan04 1.62 0.0236 122MCM1_YPD hht2_K4914182327GMartin04 1.62 0.0236 63STE12_YPD WT_V71E Chitikila_02 -1.62 0.0237 39SWI6_YPD hht2K9131823GMartin04 1.62 0.0237 131FKH2_H2O2Hi DM_vs._YPH250Rosaleny05 1.62 0.0237 94GCN4_YPD hat2_vs._YPH250Rosaleny05 -1.62 0.0237 72CBF1_SM WT_V71R Chitikila_02 -1.62 0.0238 251GCR2_SM Dpho23 Keogh05 1.62 0.0239 53ROX1_YPD Dpho23 Keogh05 -1.61 0.024 66SUT1_YPD SIR3 Hughes00 1.61 0.024 68SWI4_YPD HTZ1 Krogan04 1.61 0.024 144SWI4_YPD YAF9 Krogan04 1.61 0.024 148HSF1_H2O2LoRAD6_haploid Hughes00 1.61 0.024 100MCM1_Alpha RAD6_haploid Hughes00 1.61 0.024 106MBP1_YPD hpa2D Durant06 -1.61 0.024 102DAL81_RAPA isw2_rpd3 Fazzio01 -1.61 0.0241 91GCN4_RAPA htz1_del Mizuguch04 1.61 0.0241 159YAP6_H2O2Hi ARD1 Hughes00 -1.61 0.0241 78RCS1_H2O2Losas3D_taf1-ts2Durant06 1.61 0.0241 229STE12_BUT90 BUR6 Geisberg_01 1.61 0.0241 72PHD1_YPD DM_vs._YPH250Rosaleny05 1.61 0.0242 54CIN5_H2O2Hi HDA1 Hughes00 1.61 0.0242 76MBP1_YPD Set1_del Bernstein02 -1.61 0.0242 129YAP1_YPD DT_V161E Chitikila_02 -1.61 0.0243 68GLN3_RAPA YNG2 Mnaimneh_04 1.61 0.0243 68REB1_H2O2Hi SWR1 Krogan04 -1.61 0.0243 54SWI6_YPD MED2_haploid Hughes00 -1.61 0.0244 153YAP6_YPD isw2_ume6 Fazzio01 1.61 0.0244 88RCS1_H2O2Hi gcn5_KQL Huisinga04 1.61 0.0244 46SUT1_YPD 0.1%_MMS Attikum04 -1.61 0.0245 50UME6_YPD isw2_rpd3_vs._rpd3Fazzio01 1.61 0.0245 125SKN7_H2O2HiSIR2 Hughes00 -1.61 0.0245 97RIM101_H2O2Loswi1_minimal_medium_experimentSudarsanam00 1.61 0.0245 54SUT1_YPD isw2_ume6 Fazzio01 1.6 0.0246 69SWI4_YPD gcn5D Durant06 -1.6 0.0246 134YAP6_YPD WT Durant06 -1.6 0.0246 83RTG3_RAPA WT_V161E Chitikila_02 -1.6 0.0246 51CIN5_H2O2Hi sin3 Fazzio01 -1.6 0.0246 79FKH2_H2O2Hi WT Durant06 1.6 0.0246 98NRG1_H2O2Hisir2 Meneghini03 1.6 0.0246 123UME6_YPD isw2_c.i. Fazzio01 -1.6 0.0247 125UME6_H2O2Hitaf1-ts2_gcn5_KQLHuisinga04 1.6 0.0247 89YAP6_H2O2Hi SIR2 Hughes00 1.6 0.0247 77YAP7_H2O2Lo htz1_del Mizuguch04 1.6 0.0247 151NRG1_YPD ume6_del Bernstein_00_affydeletions1.6 0.0247 54REB1_YPD WT_Null_K Chitikila_02 1.6 0.0248 132CIN5_YPD DT_V71E Chitikila_02 -1.6 0.0248 145MSN4_RAPA HIR2 Hughes00 -1.6 0.0248 53MBP1_H2O2Hihat2_vs._hat1Rosaleny05 -1.6 0.0248 127CIN5_H2O2Lo htz1 Meneghini03 -1.6 0.0248 124SKN7_H2O2Lotaf1-ts2_spt3_E240KHuisinga04 1.6 0.0248 163DIG1_Alpha ISW2 Hughes00 -1.6 0.0248 60ABF1_YPD ISW2 Hughes00 1.6 0.0249 267

YAP7_H2O2Hi htz1_del Mizuguch04 1.6 0.0249 140HSF1_H2O2Loarp8_+_0.1%_MMS_vs._arp8Attikum04 1.6 0.0249 88ASH1_BUT14 RPD3_haploid Hughes00 1.6 0.0249 49FKH1_YPD taf1-ts2_SPT3 Huisinga04 -1.6 0.0249 136MCM1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.6 0.0249 60STE12_YPD hht2_K914182327GMartin04 -1.6 0.025 43UME6_YPD Dpho23 Keogh05 1.6 0.025 130STE12_Alpha delta_ssd1 Kaeberlein04 1.6 0.025 114ASH1_BUT14 hht2_K27G Martin04 1.6 0.025 42ACE2_YPD YNG2 Mnaimneh_04 1.6 0.025 80YAP6_H2O2Hi hos2_del Bernstein_00_affydeletions-1.6 0.0251 68RIM101_H2O2Loino80 Attikum04 1.6 0.0251 33DIG1_BUT14 hos2_del Bernstein_00_affydeletions1.6 0.0251 61MBP1_YPD YAF9 Krogan04 1.6 0.0251 126NDD1_YPD hpa2D Durant06 -1.59 0.0252 71NDD1_YPD WT_V71E Chitikila_02 -1.59 0.0252 81PHD1_YPD WT_N69S Chitikila_02 -1.59 0.0253 59YAP1_YPD hht2_K27G Martin04 1.59 0.0253 62CIN5_YPD snf2_minimal_medium_experimentSudarsanam00 1.59 0.0253 149RTG3_RAPA WT_V71E Chitikila_02 -1.59 0.0253 44HSF1_H2O2LoWT_Null_L Chitikila_02 -1.59 0.0253 91FKH2_H2O2Hi WT_V161R_L Chitikila_02 -1.59 0.0254 98XBP1_H2O2Lo rpd3_H3dN_v_H3dNSabet04 1.59 0.0254 56ASH1_BUT14 taf1-ts2_gcn5 Huisinga04 1.59 0.0254 44GCN4_YPD RAD6_haploid Hughes00 1.59 0.0254 74CBF1_SM swr1 Meneghini03 1.59 0.0255 225YAP7_H2O2Hi Rpd3_del Bernstein02 1.59 0.0255 141AFT2_H2O2Lo SWC6_(VPS71)Krogan04 1.59 0.0255 87GCR2_SM SIR3 Hughes00 1.59 0.0256 54PUT3_H2O2Lo isw2_c.i._rpd3_c.i.Fazzio01 -1.59 0.0256 86YAP6_YPD HIR2 Hughes00 1.59 0.0257 90YAP6_H2O2Hi elp3D_taf1-ts2Durant06 -1.59 0.0257 53PHD1_BUT90 SIR3 Hughes00 1.59 0.0257 104ACE2_YPD WT_N69R Chitikila_02 -1.59 0.0257 69NRG1_H2O2HiTAF2 Mnaimneh_04 1.58 0.0258 126UME6_H2O2Hitaf1-ts2_GCN5Huisinga04 1.58 0.0258 93SOK2_BUT14 rsc3-2 Angus-Hill_01 1.58 0.0258 71ACE2_YPD sir4 Orlandi04 -1.58 0.0258 59HAP4_YPD hat2_vs._YPH250Rosaleny05 1.58 0.0258 62SWI4_YPD hos2_del Bernstein_00_affydeletions1.58 0.026 146CIN5_YPD isw2_rpd3_vs._rpd3Fazzio01 -1.58 0.026 147UME6_H2O2Hirpd3_H4KQ_v_H4KQSabet04 1.58 0.026 99DAL82_SM isw2_c.i. Fazzio01 -1.58 0.0261 50DIG1_Alpha Dsap30 Keogh05 -1.58 0.0261 59STE12_BUT14 MOT1-14 Dasgupta02 1.58 0.0261 128ACE2_YPD WT_V161E Chitikila_02 -1.58 0.0261 76HAP1_YPD ARD1 Hughes00 -1.58 0.0261 141CBF1_SM swi1_rich_medium_experimentSudarsanam00 1.58 0.0262 277AFT2_H2O2Hi WT_TAF1_GCN5Huisinga04 1.58 0.0262 59SKN7_H2O2LoDT_V161R_L Chitikila_02 -1.58 0.0262 176MCM1_Alpha WT_V161E Chitikila_02 1.58 0.0262 97GCN4_YPD hat1_vs.YPH250Rosaleny05 -1.58 0.0263 72ABF1_YPD SWR1 Krogan04 -1.57 0.0264 247

DAL82_RAPA HDA1 Hughes00 1.57 0.0264 56MSN2_H2O2Higcn5_KQL Huisinga04 1.57 0.0264 65DIG1_BUT14 sas3D_taf1-ts2Durant06 1.57 0.0264 57FKH1_YPD Set1_del Bernstein02 -1.57 0.0264 141ABF1_YPD elp3D Durant06 1.57 0.0265 220UME6_YPD gcn5D Durant06 1.57 0.0265 106RPN4_H2O2Loubp10sir4 Orlandi04 -1.57 0.0265 81PHD1_YPD DT_V161R_K Chitikila_02 1.57 0.0266 67FKH2_YPD SGF11 Ingvarsdottir05 -1.57 0.0266 97PHD1_YPD htz1_sir2 Meneghini03 -1.57 0.0267 67MBP1_H2O2HiHAT2 Hughes00 1.57 0.0267 130REB1_H2O2Hi rsc3-2 Angus-Hill_01 1.57 0.0267 57STE12_BUT14 ino80_del Mizuguch04 -1.57 0.0267 128SUT1_YPD Ddep1 Keogh05 -1.57 0.0268 64DAL82_SM set1 Boa03 -1.57 0.0268 54GCN4_SM hht2_K49141823GMartin04 1.57 0.0268 163XBP1_H2O2Lo taf1-ts2_spt3_E240KHuisinga04 -1.57 0.0268 62FKH1_YPD MOT1-42 Dasgupta02 -1.57 0.0268 142FKH1_YPD taf1-ts2_gcn5 Huisinga04 -1.57 0.0268 133RLM1_YPD RSC8 Mnaimneh_04 1.57 0.0269 55MBP1_H2O2Losnf2_minimal_medium_experimentSudarsanam00 1.57 0.0269 57STE12_BUT90 arp8 Attikum04 -1.57 0.0269 67STE12_YPD TUP1_haploid Hughes00 -1.56 0.027 52YAP1_YPD WT_V71R Chitikila_02 -1.56 0.027 66GLN3_RAPA isw2_ume6 Fazzio01 -1.56 0.027 67AFT2_H2O2Hi gcn5_KQL Huisinga04 1.56 0.027 57MSN4_H2O2HiSIR1 Hughes00 1.56 0.027 68PUT3_H2O2Lo isw2_c.i. Fazzio01 -1.56 0.027 86DIG1_Alpha RPD3_haploid Hughes00 -1.56 0.027 59MCM1_Alpha MED2_haploid Hughes00 -1.56 0.027 106SOK2_BUT14 DT_WT Chitikila_02 -1.56 0.027 70MGA1_YPD RAD6_haploid Hughes00 -1.56 0.027 62CBF1_SM _SWC2_(VPS72)Krogan04 1.56 0.0271 241CBF1_SM SIR4 Hughes00 1.56 0.0271 276MSN2_H2O2HiUBP8 Hughes00 1.56 0.0271 77NRG1_H2O2Hiume6 Fazzio01 -1.56 0.0271 123RCS1_H2O2Hi hat1D Durant06 -1.56 0.0271 38MCM1_Alpha BUR6 Geisberg_01 1.56 0.0271 103CIN5_H2O2Hi EAF7 Krogan04 -1.56 0.0272 72HSF1_H2O2Hi sap30_del Bernstein_00_affydeletions1.56 0.0272 119YAP7_H2O2Hi hpa2D_taf1-ts2Durant06 1.56 0.0272 117DIG1_Alpha DT_WT Chitikila_02 -1.56 0.0272 57MBP1_H2O2HiDrpd3 Keogh05 1.56 0.0273 126MSN4_H2O2HiSSD1-V Kaeberlein04 1.56 0.0273 70MBP1_H2O2LoSIR2 Hughes00 -1.56 0.0273 58STE12_BUT14 Set1_del Bernstein02 -1.56 0.0273 126SUT1_YPD taf1-ts2_spt3_E240KHuisinga04 -1.56 0.0274 61SUT1_YPD SIR2 Hughes00 1.56 0.0274 69YAP6_YPD esa1-414 Durant06 -1.56 0.0274 82STE12_Alpha isw2_ume6 Fazzio01 -1.56 0.0274 112ASH1_BUT14 hpa2D_taf1-ts2Durant06 1.56 0.0274 39ACE2_YPD TAF2 Mnaimneh_04 1.56 0.0274 80NDD1_YPD swi1_rich_medium_experimentSudarsanam00 -1.56 0.0274 85

PHD1_YPD SWR1 Krogan04 -1.56 0.0275 62DAL82_SM taf1-ts2_gcn5_KQLHuisinga04 1.56 0.0275 52MSN2_H2O2Hiisw2_rpd3_vs._rpd3Fazzio01 -1.56 0.0275 75CIN5_H2O2Lo Rpd3_del Bernstein02 -1.56 0.0275 125SKN7_H2O2Loelp3D Durant06 1.56 0.0275 147PHD1_BUT90 WT_N69R Chitikila_02 -1.56 0.0275 98SKN7_YPD DT_N69R Chitikila_02 1.55 0.0277 62UME6_YPD DT_N69R Chitikila_02 1.55 0.0277 112MBP1_H2O2Hi taf1-ts2 Durant06 1.55 0.0277 131SKN7_H2O2HiDT_V161R_L Chitikila_02 -1.55 0.0277 92YAP6_H2O2Hi MOT1-42 Dasgupta02 1.55 0.0277 79HSF1_H2O2LoHST3 Hughes00 1.55 0.0277 99XBP1_H2O2Lo taf1-ts2_spt3 Huisinga04 -1.55 0.0277 65HAP4_YPD WT_TAF1_SPT3Huisinga04 1.55 0.0277 63YAP1_YPD SSN6_haploid Hughes00 1.55 0.0278 71YAP6_H2O2Hi H4_2-26 Sabet04 1.55 0.0278 71SOK2_BUT14 htz1_sir2 Meneghini03 1.55 0.0278 70SWI4_YPD swr1 Meneghini03 1.55 0.0279 123CIN5_YPD WT_N69R Chitikila_02 -1.55 0.0279 138GLN3_RAPA DM_vs._YPH250Rosaleny05 1.55 0.0279 62NRG1_H2O2HiWT_Null_K Chitikila_02 -1.55 0.0279 119RCS1_H2O2Hi Rpd3_del Bernstein02 1.55 0.0279 52NRG1_YPD sin3_del Bernstein_00_affydeletions-1.55 0.0279 55AFT2_H2O2Hi sir4 Orlandi04 -1.55 0.028 37FKH2_H2O2Hi HST3 Hughes00 -1.55 0.028 105MSN2_H2O2HiSAP30 Hughes00 1.55 0.028 76NRG1_H2O2HiWT_Null_L Chitikila_02 1.55 0.028 118YAP7_H2O2Lo Dsap30 Keogh05 1.55 0.028 143SOK2_BUT14 isw2_rpd3_vs._rpd3Fazzio01 -1.55 0.028 71GCN4_YPD taf1-ts2_spt3 Huisinga04 -1.55 0.028 70NDD1_YPD hht2_K4914182327GMartin04 1.55 0.028 75SUT1_YPD MOT1-14 Dasgupta02 1.55 0.0281 69SWI5_YPD H3KQ Sabet04 1.55 0.0281 93DAL82_SM swi1_minimal_medium_experimentSudarsanam00 -1.55 0.0281 55NRG1_H2O2Hiino80 Attikum04 1.55 0.0281 88PHD1_YPD DT_N69S Chitikila_02 -1.54 0.0282 58SWI5_YPD elp3D_taf1-ts2Durant06 1.54 0.0282 81SKN7_H2O2HiDrxt1 Keogh05 -1.54 0.0282 97HSF1_H2O2LoDeaf3 Keogh05 1.54 0.0282 91HSF1_H2O2Lotaf1-ts2_gcn5_KQLHuisinga04 1.54 0.0282 82STE12_Alpha snf2_rich_medium_experimentSudarsanam00 -1.54 0.0282 114HAP4_YPD Drxt2 Keogh05 -1.54 0.0282 61YAP6_H2O2Hi DT_N69R Chitikila_02 1.54 0.0283 72RPN4_H2O2Lorpd3_c.i. Fazzio01 1.54 0.0283 97FKH2_YPD swi1_rich_medium_experimentSudarsanam00 -1.54 0.0283 121RLM1_YPD isw2_rpd3_vs._rpd3Fazzio01 -1.54 0.0284 54SWI6_YPD Drxt1 Keogh05 -1.54 0.0284 152PUT3_H2O2Lo DT_N69R Chitikila_02 1.54 0.0284 79PHD1_BUT90 SSD1-V Kaeberlein04 1.54 0.0284 105MGA1_YPD elp3D Durant06 -1.54 0.0284 48YAP1_YPD SPT8 Ingvarsdottir05 1.54 0.0285 65GCN4_SM hat2_vs._YPH250Rosaleny05 -1.54 0.0285 180MSN2_H2O2HiRAD6_haploid Hughes00 1.54 0.0285 77

MSN2_H2O2Hirpd3_H3dN_v_H3dNSabet04 1.54 0.0285 74GCR2_SM hmr Meneghini03 -1.54 0.0286 53REB1_YPD elp3D Durant06 1.54 0.0287 120SKN7_H2O2LoYAF9 Krogan04 1.54 0.0287 173RLM1_YPD elp3D Durant06 -1.54 0.0288 47SWI4_YPD Hda1_del Bernstein02 1.54 0.0288 154CIN5_YPD HDA1 Hughes00 1.54 0.0288 149AFT2_H2O2Hi UBP8 Ingvarsdottir05 1.54 0.0288 55FKH2_H2O2Hi hat1_vs.YPH250Rosaleny05 1.54 0.0288 100RIM101_H2O2Loume6 Fazzio01 1.54 0.0288 52FKH1_YPD swr1_del Mizuguch04 1.54 0.0288 140MBP1_H2O2HiH4KQ Sabet04 -1.53 0.0289 129STE12_BUT14 EPL1 Mnaimneh_04 1.53 0.0289 128MGA1_YPD taf1-ts2_spt3 Huisinga04 1.53 0.0289 59SUM1_YPD spt3 Huisinga04 -1.53 0.029 53SWI5_YPD isw2_sin3 Fazzio01 -1.53 0.029 94YAP7_H2O2Hi hht2_K4914182327GMartin04 -1.53 0.029 124FKH2_H2O2Hi htz1_hmr Meneghini03 1.53 0.0291 105STE12_BUT90 0.1%_MMS Attikum04 -1.53 0.0291 68MSN2_H2O2Hisin3 Fazzio01 1.53 0.0292 75SWI4_YPD Drpd3 Keogh05 1.53 0.0293 146GCN4_SM elp3D Durant06 1.53 0.0293 158GCR2_SM _SWC2_(VPS72)Krogan04 1.53 0.0293 52YAP7_H2O2Lo rsc3-2 Angus-Hill_01 1.53 0.0293 148GCN4_SM DT_V161R_L Chitikila_02 -1.53 0.0294 178CIN5_H2O2Hi SWR1 Krogan04 -1.53 0.0294 71NRG1_H2O2HiSIR2 Hughes00 1.53 0.0294 126SKN7_H2O2Hi hht2_K4G Martin04 1.53 0.0294 73DIG1_Alpha YNG2 Mnaimneh_04 -1.53 0.0294 60MCM1_Alpha hht2_K4914182327GMartin04 1.53 0.0294 92HAP4_YPD WT_Null_K Chitikila_02 1.53 0.0294 64SWI6_YPD DT_N69R Chitikila_02 -1.53 0.0295 144GCR2_SM EAF7 Krogan04 1.53 0.0295 49AFT2_H2O2Hi snf2_rich_medium_experimentSudarsanam00 1.53 0.0295 61YAP7_H2O2Hi ume6_del Bernstein_00_affydeletions1.53 0.0295 138SKN7_H2O2LoDT_V71E Chitikila_02 -1.53 0.0295 178PHD1_BUT90 hmr Meneghini03 -1.53 0.0295 104NDD1_YPD esa1-414_taf1-ts2Durant06 1.53 0.0295 76HSF1_H2O2Hi ume6 Fazzio01 1.52 0.0296 119PUT3_H2O2Lo snf2_minimal_medium_experimentSudarsanam00 1.52 0.0296 88ASH1_BUT14 isw2_ume6 Fazzio01 1.52 0.0296 49ACE2_YPD sin3_del Bernstein_00_affydeletions-1.52 0.0296 73PHO4_YPD sas3D Durant06 -1.52 0.0297 62AFT2_H2O2Hi H4KQ Sabet04 1.52 0.0297 57UME6_H2O2Hirpd3_del Sabet04 1.52 0.0297 99PHD1_YPD SIR1 Hughes00 1.52 0.0298 66YAP6_YPD WT_V161R_K Chitikila_02 1.52 0.0298 84GCN4_SM taf1-ts2_25C Huisinga04 1.52 0.0298 173RTG3_RAPA SIR4 Hughes00 1.52 0.0298 52MSN4_H2O2HiWT_WT Chitikila_02 1.52 0.0298 69SKN7_H2O2LoH3_1-28 Sabet04 1.52 0.0298 177SWI4_YPD htz1_hmr Meneghini03 1.52 0.0299 153DAL81_RAPA WT Durant06 -1.52 0.0299 91

MSN4_H2O2HiDM_vs._YPH250Rosaleny05 1.52 0.0299 66STE12_YPD ume6 Fazzio01 -1.52 0.03 54SWI4_YPD WT_Null_L Chitikila_02 1.52 0.03 150AFT2_H2O2Lo isw2_c.i._rpd3_c.i.Fazzio01 -1.52 0.03 95FKH2_YPD swr1 Meneghini03 1.52 0.03 105OAF1_YPD hpa2D Durant06 -1.52 0.03 44AFT2_H2O2Lo swr1_del Mizuguch04 1.52 0.0301 98DIG1_BUT14 sir4 Orlandi04 -1.52 0.0301 46PHD1_BUT90 DM_vs._YPH250Rosaleny05 1.52 0.0301 90FKH2_YPD SWR1 Krogan04 1.52 0.0301 115SUT1_YPD hat1D_taf1-ts2Durant06 1.51 0.0302 55CIN5_YPD WT_V71R Chitikila_02 -1.51 0.0302 141MSN2_H2O2Hisir4 Orlandi04 -1.51 0.0303 51YAP7_H2O2Lo Dume1 Keogh05 1.51 0.0303 143OAF1_YPD MOT1-42 Dasgupta02 1.51 0.0303 58GCN4_YPD swr1_del Mizuguch04 1.51 0.0304 75GCN4_YPD DT_V71E Chitikila_02 1.51 0.0304 73PHD1_YPD esa1-414_taf1-ts2Durant06 1.51 0.0305 54UME6_YPD gcn5 Huisinga04 1.51 0.0305 124YAP6_YPD rpd3_H3dN_v_H3dNSabet04 1.51 0.0305 82RTG3_RAPA esa1-414_taf1-ts2Durant06 1.51 0.0305 47MBP1_H2O2LoWT_V161R_L Chitikila_02 -1.51 0.0305 52STE12_YPD hpa2D Durant06 -1.51 0.0306 38AFT2_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 1.51 0.0306 46CIN5_YPD H4KQ Sabet04 1.51 0.0307 144NRG1_H2O2Hitaf1-ts2_SPT3 Huisinga04 1.51 0.0307 110RPN4_H2O2Loswr1 Meneghini03 1.51 0.0307 82MCM1_Alpha EPL1 Mnaimneh_04 1.51 0.0307 106ASH1_BUT14 H3_1-28 Sabet04 1.51 0.0307 47PHD1_BUT90 sap30_del Bernstein_00_affydeletions-1.51 0.0307 88ABF1_YPD taf1-ts2_spt3_E240KHuisinga04 1.51 0.0308 251ROX1_YPD DT_WT Chitikila_02 -1.51 0.0308 65CIN5_H2O2Hi htz1_hmr Meneghini03 -1.51 0.0308 80SKN7_H2O2HiWT Durant06 -1.51 0.0308 92MBP1_YPD hht2K9131823GMartin04 1.51 0.0308 115RLM1_YPD rpd3 Fazzio01 -1.51 0.0309 54MSN2_H2O2HiEAF5 Krogan04 1.51 0.0309 68STE12_Alpha swi1_minimal_medium_experimentSudarsanam00 -1.51 0.0309 113DIG1_BUT14 Dsap30 Keogh05 -1.51 0.0309 63MCM1_YPD snf2_minimal_medium_experimentSudarsanam00 -1.51 0.0309 77PHD1_YPD spt10_del Xu05 -1.5 0.031 66SKN7_YPD hpa2D_taf1-ts2Durant06 1.5 0.031 52ASH1_BUT14 HTZ1 Krogan04 1.5 0.031 44HSF1_H2O2Hi rpd3_c.i. Fazzio01 -1.5 0.0311 119YAP7_H2O2Hi ino80_del Mizuguch04 1.5 0.0311 141SKN7_H2O2LoSIR3 Hughes00 1.5 0.0311 184SKN7_H2O2Lohos2_del Bernstein_00_affydeletions1.5 0.0311 163MCM1_Alpha Drxt2 Keogh05 1.5 0.0311 104ACE2_YPD sap30_del Bernstein_00_affydeletions1.5 0.0311 74NRG1_YPD MED2_haploid Hughes00 1.5 0.0311 71PHD1_YPD gcn5 Huisinga04 1.5 0.0312 60RLM1_YPD rpd3_del Sabet04 -1.5 0.0312 50MSN2_H2O2HiDsin3 Keogh05 1.5 0.0312 71

SKN7_H2O2Hi EAF5 Krogan04 1.5 0.0312 81PHD1_BUT90 swr1 Meneghini03 -1.5 0.0313 87HAP4_YPD UBP8 Ingvarsdottir05 -1.5 0.0313 58SWI5_YPD WT_N69R Chitikila_02 -1.5 0.0314 91HSF1_H2O2Hi sin3_del Bernstein_00_affydeletions1.5 0.0314 119SWI4_YPD WT Durant06 1.5 0.0315 150NDD1_YPD Dpho23 Keogh05 1.5 0.0315 84AFT2_H2O2Hi ubp10sir4 Orlandi04 1.5 0.0316 39MBP1_H2O2HiSIR4 Hughes00 1.5 0.0316 133RTG3_RAPA hmr Meneghini03 -1.49 0.0317 50PUT3_H2O2Lo ubp10 Orlandi04 1.49 0.0317 49PUT3_H2O2Lo WT Durant06 -1.49 0.0317 79ABF1_YPD sas3D Durant06 1.49 0.0318 229ABF1_YPD htz1_del Mizuguch04 -1.49 0.0318 267SWI4_YPD snf2_minimal_medium_experimentSudarsanam00 -1.49 0.0318 156HSF1_H2O2Lohda1_del Bernstein_00_affydeletions1.49 0.0318 96STE12_BUT14 RPD3_haploid Hughes00 -1.49 0.0318 127SKN7_YPD hht2_K49141823GMartin04 1.49 0.0319 51AFT2_H2O2Hi ISW1 Hughes00 -1.49 0.0319 58NRG1_H2O2HiSIR1 Hughes00 1.49 0.0319 121XBP1_H2O2Lo rsc30_null Angus-Hill_01 -1.49 0.0319 67MCM1_Alpha SIR2 Hughes00 -1.49 0.032 105SOK2_BUT14 0.1%_MMS Attikum04 -1.49 0.032 49SWI5_YPD WT_V161R_L Chitikila_02 -1.49 0.0321 91STE12_BUT14 SWR1 Krogan04 1.49 0.0321 121HAP4_YPD SWC6_(VPS71)Krogan04 1.49 0.0321 55SUT1_YPD DT_WT Chitikila_02 -1.49 0.0322 62SWI6_YPD swi1_rich_medium_experimentSudarsanam00 -1.49 0.0322 153FKH2_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -1.49 0.0322 96GLN3_RAPA ZDS1 Hughes00 1.49 0.0323 67FKH2_H2O2Hi ISW1 Hughes00 1.49 0.0323 104MSN2_H2O2Hihht2_K49141823GMartin04 1.49 0.0323 60STE12_BUT90 taf1-ts2 Durant06 1.49 0.0323 76STE12_YPD taf1-ts2_spt3 Huisinga04 -1.48 0.0324 47DAL82_SM snf2_minimal_medium_experimentSudarsanam00 -1.48 0.0324 55MBP1_H2O2HiBUR6 Geisberg_01 -1.48 0.0324 122NDD1_YPD SIN3 Hughes00 1.48 0.0324 81XBP1_H2O2Lo Drxt2 Keogh05 -1.48 0.0325 67MCM1_Alpha EAF7 Krogan04 1.48 0.0325 99SWI6_YPD TUP1_haploid Hughes00 -1.48 0.0326 152ACE2_YPD elp3D_taf1-ts2Durant06 1.48 0.0326 64SWI4_YPD SSN6_haploid Hughes00 1.48 0.0327 156RIM101_H2O2Losir4 Orlandi04 -1.48 0.0327 21NDD1_YPD swi1_minimal_medium_experimentSudarsanam00 -1.48 0.0327 85ROX1_YPD esa1-414_taf1-ts2Durant06 -1.48 0.0328 52SWI6_YPD isw2_rpd3_vs._rpd3Fazzio01 1.48 0.0328 148MBP1_H2O2HiSPT3 Ingvarsdottir05 1.48 0.0328 116MBP1_YPD EAF7 Krogan04 1.48 0.0328 123GCN4_SM taf1-ts2_gcn5 Huisinga04 1.48 0.0329 183YAP6_YPD Drxt2 Keogh05 -1.48 0.033 88CIN5_YPD taf1-ts2 Durant06 1.48 0.033 147GLN3_RAPA htz1_del Mizuguch04 1.48 0.033 68REB1_H2O2Hi rsc30_null Angus-Hill_01 1.48 0.033 57

HSF1_H2O2Loswi1_minimal_medium_experimentSudarsanam00 -1.48 0.033 101ACE2_YPD ubp10sir4 Orlandi04 -1.48 0.033 61MCM1_YPD IOC4 Hughes00 1.48 0.033 76SKN7_YPD WT_N69S Chitikila_02 -1.48 0.0331 64UME6_YPD taf1-ts2_25C Huisinga04 1.47 0.0332 122YAP6_YPD Dpho23 Keogh05 -1.47 0.0332 89GLN3_RAPA hat1D_taf1-ts2Durant06 1.47 0.0332 55RCS1_H2O2Hi WT_TAF1_SPT3Huisinga04 1.47 0.0332 46STE12_Alpha hmr Meneghini03 -1.47 0.0332 113NDD1_YPD hat1_vs.YPH250Rosaleny05 1.47 0.0332 81DAL82_RAPA gcn5D_taf1-ts2Durant06 1.47 0.0333 52YAP7_H2O2Lo taf1-ts2_gcn5 Huisinga04 1.47 0.0333 147DIG1_Alpha isw2_sin3 Fazzio01 -1.47 0.0333 59DIG1_BUT14 esa1-414 Durant06 1.47 0.0333 59SWI4_YPD taf1-ts2_gcn5_KQLHuisinga04 -1.47 0.0334 120YAP6_YPD rpd3_del Sabet04 -1.47 0.0334 82RPN4_H2O2LoWT_Null_K Chitikila_02 1.47 0.0334 98SOK2_BUT14 DT_N69S Chitikila_02 -1.47 0.0334 66NRG1_YPD DT_Null Chitikila_02 -1.47 0.0334 67OAF1_YPD isw2_sin3 Fazzio01 1.47 0.0334 56MSN4_H2O2HiISW1 Hughes00 1.47 0.0335 69MSN4_H2O2Hihtz1_hmr Meneghini03 1.47 0.0335 70RCS1_H2O2Hi ARD1 Hughes00 1.47 0.0335 52CIN5_H2O2Lo HIR2 Hughes00 1.47 0.0335 126UME6_YPD hat1D_taf1-ts2Durant06 1.47 0.0336 100YAP6_YPD SIR2 Hughes00 1.47 0.0336 90YAP6_YPD VID21 Krogan04 1.47 0.0336 83CBF1_SM ZDS1 Hughes00 1.47 0.0336 277SOK2_BUT14 WT_N69S Chitikila_02 -1.47 0.0336 68CIN5_H2O2Hi ino80_del Mizuguch04 -1.47 0.0337 80STE12_Alpha Set1_del Bernstein02 -1.47 0.0337 111CBF1_SM YNG2 Mnaimneh_04 1.47 0.0338 279DAL82_RAPA Set1_del Bernstein02 1.47 0.0338 55FKH2_H2O2Hi swi1_rich_medium_experimentSudarsanam00 -1.47 0.0338 106MSN2_H2O2Hirpd3_del Sabet04 1.47 0.0338 74MCM1_Alpha SIN3 Hughes00 1.47 0.0338 105ROX1_YPD WT_V71R Chitikila_02 1.46 0.0339 65DAL81_RAPA HTZ1 Krogan04 1.46 0.0339 90GLN3_RAPA WT_F182V Chitikila_02 1.46 0.0339 55CIN5_H2O2Hi MED2_haploid Hughes00 1.46 0.0339 79YAP6_H2O2Lo delta_ssd1 Kaeberlein04 -1.46 0.0339 58REB1_YPD RPD3_haploid Hughes00 1.46 0.0341 140GLN3_RAPA SPT3 Ingvarsdottir05 1.46 0.0341 63FKH2_YPD H4KQ Sabet04 1.46 0.0341 119CBF1_SM ume6_del Bernstein_00_affydeletions1.46 0.0342 266XBP1_H2O2Lo SIR1 Hughes00 1.46 0.0342 67ACE2_YPD SIR4 Hughes00 1.46 0.0342 80CIN5_YPD rpd3_del Sabet04 -1.46 0.0343 144CIN5_H2O2Lo SPT8 Ingvarsdottir05 -1.46 0.0343 114YAP6_YPD ume6 Fazzio01 1.46 0.0344 88MBP1_H2O2LoMOT1-42 Dasgupta02 -1.46 0.0344 57SKN7_H2O2LoMOT1-14 Dasgupta02 1.46 0.0344 184MCM1_Alpha DT_N69R Chitikila_02 1.46 0.0344 102

FKH1_YPD ARD1 Hughes00 -1.46 0.0344 141SOK2_BUT14 DT_Null Chitikila_02 1.46 0.0344 70YAP6_YPD sap30_del Bernstein_00_affydeletions-1.46 0.0345 77MCM1_YPD esa1-414 Durant06 1.46 0.0345 66SKN7_YPD SIR4 Hughes00 1.46 0.0346 66YAP1_YPD UBP8 Ingvarsdottir05 1.46 0.0346 67GCN4_RAPA H4_2-26 Sabet04 1.46 0.0346 155RCS1_H2O2Hi isw2_sin3 Fazzio01 -1.46 0.0346 50FKH2_YPD WT_V161R_K Chitikila_02 -1.46 0.0346 110MCM1_YPD RAD6_haploid Hughes00 1.46 0.0346 76RPN4_H2O2LoWT_N69S Chitikila_02 1.45 0.0347 93FKH1_YPD rpd3_c.i. Fazzio01 1.45 0.0347 139GCN4_YPD YNG2 Mnaimneh_04 1.45 0.0347 75GCN4_YPD WT_V161R_K Chitikila_02 -1.45 0.0348 69MCM1_Alpha RPD3_haploid Hughes00 1.45 0.0349 106MCM1_Alpha hpa2D Durant06 -1.45 0.0349 79SWI5_YPD spt10 Eriksson05 -1.45 0.035 100MSN4_RAPA Hda1_del Bernstein02 -1.45 0.035 54MBP1_H2O2LoUBP8 Ingvarsdottir05 1.45 0.035 54RCS1_H2O2Loelp3D Durant06 1.45 0.035 216MBP1_YPD hht2_K4914182327GMartin04 1.45 0.035 115YAP6_YPD gcn5 Huisinga04 1.45 0.0351 86DAL82_SM YNG2 Mnaimneh_04 1.45 0.0351 55AFT2_H2O2Hi DM_vs._YPH250Rosaleny05 1.45 0.0351 56FKH2_H2O2Hi IOC4 Hughes00 1.45 0.0351 104SKN7_YPD spt10 Eriksson05 -1.45 0.0352 67MBP1_YPD DT_Null Chitikila_02 -1.45 0.0352 125MGA1_YPD Dsap30 Keogh05 -1.45 0.0352 60RIM101_H2O2LoDdep1 Keogh05 -1.45 0.0353 53PHD1_BUT90 isw2 Fazzio01 1.45 0.0353 102MCM1_YPD WT_Null_K Chitikila_02 -1.45 0.0353 73NDD1_YPD EAF7 Krogan04 1.45 0.0353 78CIN5_YPD elp3D Durant06 -1.45 0.0354 121SKN7_H2O2Lodelta_ssd1 Kaeberlein04 1.45 0.0354 185HAP1_YPD hat2_vs._YPH250Rosaleny05 1.44 0.0355 135MBP1_YPD hpa2D_taf1-ts2Durant06 -1.44 0.0355 102DAL82_RAPA elp3D_taf1-ts2Durant06 1.44 0.0356 44GCN4_RAPA sas3D Durant06 -1.44 0.0356 133RTG3_RAPA SPT3 Ingvarsdottir05 -1.44 0.0356 45SKN7_H2O2HiHTZ1 Krogan04 1.44 0.0357 85MBP1_H2O2Lohpa2D_taf1-ts2Durant06 -1.44 0.0357 44YAP7_H2O2Lo DT_V161R_L Chitikila_02 1.44 0.0357 139STE12_BUT90 taf1-ts2_spt3_E240KHuisinga04 -1.44 0.0357 69SUT1_YPD gcn5D_taf1-ts2Durant06 1.44 0.0358 61STP1_SM WT_WT Chitikila_02 -1.44 0.0358 64RCS1_H2O2Hi Drxt1 Keogh05 -1.44 0.0358 52STE12_BUT90 taf1-ts2_GCN5Huisinga04 1.44 0.0358 74REB1_YPD hht2_K4G Martin04 1.44 0.0359 128RLM1_YPD isw2_rpd3 Fazzio01 -1.44 0.0359 53MBP1_H2O2Hi isw2 Fazzio01 1.44 0.0359 126MBP1_H2O2Hihht2_K49141823GMartin04 1.44 0.0359 112STE12_BUT14 snf2_minimal_medium_experimentSudarsanam00 -1.44 0.0359 128YAP6_YPD htz1_del Mizuguch04 -1.44 0.0361 90

MSN2_H2O2Higcn5 Huisinga04 1.44 0.0361 77STE12_BUT14 YNG2 Krogan04 1.44 0.0361 122SKN7_YPD DT_V161R_K Chitikila_02 1.44 0.0362 67MBP1_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 1.44 0.0362 133UME6_H2O2Higcn5D Durant06 1.44 0.0362 81NRG1_YPD hat1_vs.YPH250Rosaleny05 1.44 0.0362 65YAP7_H2O2Hi rsc3-2 Angus-Hill_01 1.44 0.0363 137HAP1_YPD DT_Null Chitikila_02 1.44 0.0363 138SUT1_YPD DT_V161R_K Chitikila_02 1.43 0.0364 66SKN7_H2O2Hi taf1-ts2_25C Huisinga04 1.43 0.0364 86XBP1_H2O2Lo RSC8 Mnaimneh_04 1.43 0.0364 68NRG1_H2O2HiRPD3_haploid Hughes00 1.43 0.0365 124YAP7_H2O2Hi BUR6 Geisberg_01 1.43 0.0365 132YAP7_H2O2Lo SIR3 Hughes00 1.43 0.0365 151DIG1_Alpha rpd3 Fazzio01 -1.43 0.0365 58STE12_BUT90 SGF11 Ingvarsdottir05 -1.43 0.0365 64STE12_BUT90 RAD6_haploid Hughes00 -1.43 0.0365 76MSN4_RAPA Drco1 Keogh05 -1.43 0.0366 49FKH2_H2O2Hi SWR1 Krogan04 1.43 0.0367 102CIN5_H2O2Lo DM_vs._YPH250Rosaleny05 1.43 0.0367 110PUT3_H2O2Lo taf1-ts2_gcn5 Huisinga04 1.43 0.0367 85YAP7_H2O2Lo esa1-414 Durant06 1.43 0.0367 135YAP7_H2O2Lo sas3D_taf1-ts2Durant06 1.43 0.0367 133CIN5_H2O2Hi isw2 Fazzio01 -1.43 0.0368 79RCS1_H2O2Hi EAF5 Krogan04 1.43 0.0368 46SOK2_BUT14 SIR1 Hughes00 1.43 0.0369 71HAP4_YPD hmr Meneghini03 -1.43 0.0369 61NRG1_YPD sas3D_taf1-ts2Durant06 -1.43 0.0369 55SUT1_YPD UBP8 Hughes00 1.43 0.0371 69TYE7_YPD taf1-ts2_25C Huisinga04 -1.43 0.0371 48CIN5_YPD hht2_K914182327GMartin04 1.43 0.0371 110ASH1_BUT14 isw2_rpd3_vs._rpd3Fazzio01 1.43 0.0371 48SOK2_BUT14 arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.42 0.0372 51MBP1_H2O2Hi ino80 Attikum04 -1.42 0.0373 101HAP4_YPD ZDS1 Hughes00 1.42 0.0373 66SWI6_YPD snf2_minimal_medium_experimentSudarsanam00 -1.42 0.0374 153DAL82_RAPA WT_V161E Chitikila_02 -1.42 0.0374 52YAP7_H2O2Lo BUR6 Geisberg_01 1.42 0.0374 140DIG1_Alpha YAF9 Krogan04 1.42 0.0374 55ACE2_YPD WT_V71R Chitikila_02 -1.42 0.0374 74MGA1_YPD DT_V161E Chitikila_02 1.42 0.0374 57PHD1_YPD 0.1%_MMS Attikum04 -1.42 0.0375 45GCN4_SM ARP4 Mnaimneh_04 1.42 0.0375 189NRG1_H2O2HiDsin3 Keogh05 1.42 0.0375 107ASH1_BUT14 IOC4 Hughes00 -1.42 0.0375 50FKH1_YPD Ddep1 Keogh05 1.42 0.0375 134GCN4_SM taf1-ts2_gcn5_KQLHuisinga04 1.42 0.0376 171HSF1_H2O2Hi ubp10sir4 Orlandi04 -1.42 0.0376 95AFT2_H2O2Lo BUR6 Geisberg_01 1.42 0.0376 88HSF1_H2O2LoDT_V161R_K Chitikila_02 -1.42 0.0376 98YAP6_H2O2Lo sap30_del Bernstein_00_affydeletions-1.42 0.0376 50DIG1_BUT14 arp8 Attikum04 -1.42 0.0376 54RTG3_RAPA MOT1-42 Dasgupta02 1.42 0.0377 52

ASH1_BUT14 H3KQ Sabet04 1.42 0.0377 47GCN4_RAPA H4KQ Sabet04 1.42 0.0378 157MBP1_H2O2LoWT_TAF1_GCN5Huisinga04 -1.42 0.0378 56RIM101_H2O2LoWT_N69R Chitikila_02 1.42 0.0378 47ROX1_YPD sin3_del Bernstein_00_affydeletions-1.42 0.0379 52SWI5_YPD SAP30 Hughes00 1.42 0.0379 98GCN4_RAPA sin3_del Bernstein_00_affydeletions1.42 0.0379 155SUM1_YPD DM_vs._YPH250Rosaleny05 1.42 0.038 49SUM1_YPD IES6 Hughes00 1.42 0.038 59CIN5_YPD WT_V161R_L Chitikila_02 -1.42 0.038 144UME6_H2O2Hisir4 Orlandi04 -1.42 0.038 58RIM101_H2O2Lohht2_K49141823GMartin04 1.42 0.038 31REB1_YPD sap30_del Bernstein_00_affydeletions1.41 0.0381 138YAP6_YPD SGF11 Ingvarsdottir05 1.41 0.0381 65GLN3_RAPA DT_V71R Chitikila_02 1.41 0.0381 65RIM101_H2O2Lorpd3_H3dN_v_H3dNSabet04 1.41 0.0381 44RPN4_H2O2Loswi1_rich_medium_experimentSudarsanam00 1.41 0.0381 100YAP1_YPD RPD3_haploid Hughes00 1.41 0.0382 70RTG3_RAPA WT_Null_L Chitikila_02 1.41 0.0382 48MBP1_H2O2Hihat1_vs.YPH250Rosaleny05 1.41 0.0382 126SKN7_H2O2HiSWR1 Krogan04 1.41 0.0382 92RCS1_H2O2Lohat1_vs.YPH250Rosaleny05 1.41 0.0382 246YAP6_H2O2Lo WT_TAF1_SPT3Huisinga04 -1.41 0.0382 53STE12_BUT90 taf1-ts2_SPT3 Huisinga04 1.41 0.0382 77NRG1_H2O2Hitaf1-ts2_spt3 Huisinga04 -1.41 0.0383 115YAP6_H2O2Hi VID21 Krogan04 1.41 0.0383 74RPN4_H2O2Loino80 Attikum04 -1.41 0.0383 82NRG1_YPD RSC8 Mnaimneh_04 1.41 0.0383 72ROX1_YPD YNG2 Mnaimneh_04 1.41 0.0384 67ROX1_YPD htz1_del Mizuguch04 -1.41 0.0384 67GCN4_RAPA arp8 Attikum04 -1.41 0.0384 130GCN4_YPD gcn5D_taf1-ts2Durant06 1.41 0.0384 72HAP1_YPD Rpd3_del Bernstein02 1.41 0.0384 140MBP1_YPD isw2_ume6 Fazzio01 -1.41 0.0384 123MGA1_YPD sir4 Orlandi04 1.41 0.0385 40SKN7_YPD ino80_del Mizuguch04 1.41 0.0386 66DAL82_SM SIR3 Hughes00 1.41 0.0386 54GCR2_SM isw2_sin3 Fazzio01 -1.41 0.0386 52GCN4_RAPA DT_V161E Chitikila_02 -1.41 0.0386 154AFT2_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 1.41 0.0386 51PUT3_H2O2Lo RSC8 Mnaimneh_04 1.41 0.0386 88XBP1_H2O2Lo hat1D Durant06 -1.41 0.0386 40PHD1_BUT90 DT_Null Chitikila_02 -1.41 0.0386 104MSN2_H2O2Hiswr1 Meneghini03 1.41 0.0387 67STE12_BUT14 gcn5D_taf1-ts2Durant06 1.41 0.0387 117NDD1_YPD MED2_haploid Hughes00 -1.41 0.0387 85STE12_BUT14 DT_V161R_L Chitikila_02 -1.41 0.0388 120MSN2_H2O2Hispt3 Huisinga04 1.41 0.0389 76YAP7_H2O2Lo RSC8 Mnaimneh_04 1.41 0.0389 152NRG1_YPD Ddep1 Keogh05 -1.41 0.0389 69SKN7_YPD UBP8 Ingvarsdottir05 1.4 0.039 55YAP6_YPD snf2_rich_medium_experimentSudarsanam00 -1.4 0.039 91DAL81_RAPA H4_2-26 Sabet04 1.4 0.039 93

YAP7_H2O2Hi SIR4 Hughes00 1.4 0.039 141ASH1_BUT14 sap30_del Bernstein_00_affydeletions1.4 0.039 41ASH1_BUT14 WT_Null_L Chitikila_02 1.4 0.039 46PHD1_BUT90 MOT1-42 Dasgupta02 1.4 0.039 106STE12_BUT90 SPT8 Ingvarsdottir05 -1.4 0.039 72MBP1_YPD gcn5D Durant06 -1.4 0.039 112SUM1_YPD SAP30 Hughes00 -1.4 0.0391 57SUT1_YPD DT_V71R Chitikila_02 1.4 0.0391 65SUT1_YPD gcn5 Huisinga04 1.4 0.0391 65MSN2_H2O2HiDT_V71E Chitikila_02 -1.4 0.0391 75MSN4_H2O2Hirpd3_del Sabet04 1.4 0.0391 65STE12_YPD elp3D_taf1-ts2Durant06 1.4 0.0392 36MSN4_RAPA MOT1-42 Dasgupta02 1.4 0.0392 54STE12_Alpha Drpd3 Keogh05 -1.4 0.0392 101GCR2_SM IOC4 Hughes00 -1.4 0.0393 54FKH2_YPD delta_ssd1 Kaeberlein04 1.4 0.0393 119STE12_YPD SWD2 Mnaimneh_04 -1.4 0.0394 54CIN5_YPD htz1_del Mizuguch04 1.4 0.0394 149YAP6_H2O2Hi hht2_K49141823GMartin04 1.4 0.0394 48MBP1_H2O2Loume6_del Bernstein_00_affydeletions-1.4 0.0394 54ABF1_YPD arp8 Attikum04 -1.4 0.0395 223ABF1_YPD HDA1 Hughes00 -1.4 0.0395 266ROX1_YPD taf1-ts2_GCN5Huisinga04 -1.4 0.0395 66YAP6_YPD Dsds3 Keogh05 -1.4 0.0395 82UME6_H2O2HiSAP30 Hughes00 1.4 0.0395 100CBF1_SM hat2_vs._hat1Rosaleny05 1.4 0.0396 255STP1_SM swr1_del Mizuguch04 1.4 0.0396 68DAL82_RAPA sir2 Meneghini03 1.4 0.0396 52RPN4_H2O2LoDT_Null Chitikila_02 1.4 0.0396 96PHD1_YPD WT_V161E Chitikila_02 -1.4 0.0397 62RLM1_YPD DT_V161E Chitikila_02 -1.4 0.0397 51TYE7_YPD DT_V161R_L Chitikila_02 -1.4 0.0397 53CBF1_SM Drpd3 Keogh05 1.4 0.0397 254DAL82_SM WT_N69R Chitikila_02 -1.4 0.0397 51RIM101_H2O2LoVID21 Krogan04 1.4 0.0397 48RPN4_H2O2LoHDA1 Hughes00 -1.4 0.0397 99ACE2_YPD Dsds3 Keogh05 1.4 0.0397 76STE12_YPD sas3D_taf1-ts2Durant06 1.4 0.0398 43SUM1_YPD rsc3-2 Angus-Hill_01 -1.4 0.0398 55MSN4_RAPA Dpho23 Keogh05 -1.4 0.0398 54HAP1_YPD rsc30_null Angus-Hill_01 -1.4 0.0398 139OAF1_YPD hht2_K27G Martin04 -1.4 0.0398 44MBP1_H2O2Lotaf1-ts2_spt3_E240KHuisinga04 -1.39 0.0399 52RPN4_H2O2LoDT_V161E Chitikila_02 1.39 0.0399 96FKH2_YPD swr1_del Mizuguch04 1.39 0.0399 120ACE2_YPD gcn5_KQL Huisinga04 1.39 0.0399 67GCN4_RAPA DT_V161R_L Chitikila_02 -1.39 0.04 150STE12_YPD ino80 Attikum04 -1.39 0.0401 40YAP7_H2O2Hi gcn5D_taf1-ts2Durant06 1.39 0.0401 128HSF1_H2O2LoDT_N69S Chitikila_02 1.39 0.0401 96YAP7_H2O2Lo hht2_K4914182327GMartin04 -1.39 0.0401 128YAP1_YPD SPT3 Ingvarsdottir05 1.39 0.0402 63AFT2_H2O2Lo Dume1 Keogh05 1.39 0.0402 91

RIM101_H2O2LoISW2 Hughes00 -1.39 0.0402 53RIM101_H2O2Lohht2K9131823GMartin04 1.39 0.0402 29SOK2_BUT14 SIN3 Hughes00 -1.39 0.0402 72MCM1_YPD WT_V161E Chitikila_02 1.39 0.0402 66RCS1_H2O2Hi DT_V71R Chitikila_02 1.39 0.0403 49RPN4_H2O2Lohda1_del Bernstein_00_affydeletions1.39 0.0403 98PHD1_BUT90 sir2 Meneghini03 1.39 0.0403 105ABF1_YPD WT_TAF1_GCN5Huisinga04 1.39 0.0404 258YAP6_YPD taf1-ts2_25C Huisinga04 -1.39 0.0404 80HAP1_YPD EAF7 Krogan04 1.39 0.0404 126CBF1_SM WT_Null_L Chitikila_02 1.39 0.0405 256OAF1_YPD WT_V71R Chitikila_02 -1.39 0.0405 53CBF1_SM SWC6_(VPS71)Krogan04 1.39 0.0406 250RPN4_H2O2Lorpd3_del Sabet04 -1.39 0.0406 98YAP6_H2O2Lo taf1-ts2_spt3 Huisinga04 -1.39 0.0406 52UME6_YPD sas3D Durant06 1.39 0.0407 96CIN5_YPD swr1_del Mizuguch04 1.39 0.0407 150CIN5_YPD isw2_sin3_vs._sin3Fazzio01 -1.38 0.0408 148HSF1_H2O2LoPCH1 Hughes00 1.38 0.0408 98DIG1_Alpha _SWC2_(VPS72)Krogan04 1.38 0.0409 57CIN5_H2O2Hi SIR4 Hughes00 -1.38 0.041 79RPN4_H2O2LoISW2 Hughes00 -1.38 0.041 99XBP1_H2O2Lo htz1_sir2 Meneghini03 -1.38 0.041 67DIG1_Alpha gcn5_KQL Huisinga04 -1.38 0.041 51STE12_Alpha MOT1-14 Dasgupta02 1.38 0.041 114NRG1_YPD hpa2D_taf1-ts2Durant06 -1.38 0.041 39CIN5_H2O2Hi SIN3 Hughes00 -1.38 0.0412 79MBP1_YPD YNG2 Mnaimneh_04 1.38 0.0412 130SUM1_YPD SPT3 Ingvarsdottir05 -1.38 0.0413 47TYE7_YPD isw2_sin3_vs._sin3Fazzio01 -1.38 0.0413 54CIN5_YPD hos2_del Bernstein_00_affydeletions-1.38 0.0413 137HSF1_H2O2Hi H3KQ Sabet04 -1.38 0.0413 121PHO4_YPD rpd3 Fazzio01 1.38 0.0414 71SKN7_YPD elp3D_taf1-ts2Durant06 1.38 0.0414 51YAP1_YPD spt10_del Xu05 1.38 0.0414 69MBP1_H2O2Hi set1 Boa03 -1.38 0.0415 129NRG1_H2O2HiSWD2 Mnaimneh_04 1.38 0.0415 126YAP6_H2O2Hi ume6_del Bernstein_00_affydeletions1.38 0.0415 68RCS1_H2O2Losap30_del Bernstein_00_affydeletions1.38 0.0415 247ROX1_YPD ISW1 Hughes00 1.38 0.0416 67AFT2_H2O2Hi isw2 Fazzio01 1.38 0.0416 58MSN4_H2O2HiDdep1 Keogh05 1.38 0.0416 64MBP1_YPD PCH1 Hughes00 -1.38 0.0416 128XBP1_H2O2Lo SIR4 Hughes00 1.37 0.0417 67PHD1_BUT90 taf1-ts2_SPT3 Huisinga04 -1.37 0.0417 103STE12_BUT90 sas3D Durant06 1.37 0.0417 61ACE2_YPD UBP8 Hughes00 1.37 0.0417 80GCR2_SM YNG2 Krogan04 1.37 0.0418 52GCN4_RAPA SIN3 Hughes00 -1.37 0.0418 160HSF1_H2O2Hi Rpd3_del Bernstein02 1.37 0.0418 124PUT3_H2O2Lo UBP8 Ingvarsdottir05 1.37 0.0418 77RIM101_H2O2LoTAF2 Mnaimneh_04 -1.37 0.0418 54DIG1_BUT14 ume6_del Bernstein_00_affydeletions-1.37 0.0418 63

PHD1_YPD rpd3_del Sabet04 -1.37 0.0419 62YAP6_YPD WT_N69R Chitikila_02 1.37 0.0419 85CIN5_YPD SSD1-V Kaeberlein04 1.37 0.0419 150PHD1_BUT90 MED2_haploid Hughes00 -1.37 0.0419 105MBP1_YPD Deaf3 Keogh05 1.37 0.0419 124MGA1_YPD SPT3 Ingvarsdottir05 -1.37 0.0419 57SUT1_YPD HDA1 Hughes00 1.37 0.042 69YAP7_H2O2Hi ino80 Attikum04 1.37 0.042 121REB1_YPD DT_WT Chitikila_02 1.37 0.0421 132CBF1_SM WT_TAF1_SPT3Huisinga04 1.37 0.0421 267AFT2_H2O2Hi H4_2-26 Sabet04 1.37 0.0422 57YAP7_H2O2Lo Rpd3_del Bernstein02 1.37 0.0422 151DIG1_BUT14 taf1-ts2 Durant06 1.37 0.0422 62STE12_BUT14 DT_V71E Chitikila_02 -1.37 0.0422 119SUT1_YPD Rpd3_del Bernstein02 -1.37 0.0423 68SUT1_YPD hht2_K914182327GMartin04 1.37 0.0423 48RTG3_RAPA taf1-ts2_spt3_E240KHuisinga04 1.37 0.0423 50REB1_YPD swr1 Meneghini03 1.37 0.0424 121SKN7_YPD Drco1 Keogh05 1.37 0.0424 61CIN5_YPD RAD6_haploid Hughes00 1.37 0.0424 150STE12_Alpha ARD1 Hughes00 -1.37 0.0424 114SKN7_YPD hpa2D Durant06 -1.37 0.0425 49MBP1_H2O2Hihda1_del Bernstein_00_affydeletions-1.37 0.0425 125XBP1_H2O2Lo isw2_rpd3_vs._rpd3Fazzio01 -1.37 0.0425 64HAP1_YPD hos2_del Bernstein_00_affydeletions1.37 0.0425 134UME6_YPD sap30_del Bernstein_00_affydeletions1.37 0.0426 124GCN4_RAPA sap30_del Bernstein_00_affydeletions1.37 0.0426 154MSN4_RAPA WT_TAF1_GCN5Huisinga04 -1.37 0.0426 54CIN5_H2O2Hi spt3 Huisinga04 -1.37 0.0426 79SOK2_BUT14 BUR6 Geisberg_01 1.37 0.0426 63STE12_BUT14 HTZ1 Krogan04 1.37 0.0426 121STE12_BUT90 sin3_del Bernstein_00_affydeletions-1.37 0.0426 72HSF1_H2O2Hi Drco1 Keogh05 -1.36 0.0427 117HSF1_H2O2Hi spt3 Huisinga04 1.36 0.0427 121CIN5_H2O2Lo isw2 Fazzio01 -1.36 0.0427 125OAF1_YPD sin3 Fazzio01 1.36 0.0427 55PHD1_YPD MOT1-42 Dasgupta02 1.36 0.0428 67STE12_YPD WT_F182V Chitikila_02 1.36 0.0428 42YAP1_YPD H3KQ Sabet04 1.36 0.0428 70MSN4_H2O2Hitaf1-ts2_spt3_E240KHuisinga04 1.36 0.0429 60NRG1_H2O2HiEPL1 Mnaimneh_04 1.36 0.0429 125MBP1_YPD taf1-ts2 Durant06 1.36 0.0429 127RCS1_H2O2Hi taf1-ts2_spt3 Huisinga04 1.36 0.043 51YAP6_H2O2Hi SPT3 Ingvarsdottir05 -1.36 0.043 68YAP7_H2O2Lo elp3D_taf1-ts2Durant06 1.36 0.043 122HAP1_YPD ume6 Fazzio01 -1.36 0.043 136STE12_YPD hht2_K4G Martin04 -1.36 0.0431 43PHD1_BUT90 hht2_K4914182327GMartin04 1.36 0.0431 79NRG1_YPD DM_vs._YPH250Rosaleny05 1.36 0.0431 57OAF1_YPD rpd3 Fazzio01 1.36 0.0431 56DAL82_SM swi1_rich_medium_experimentSudarsanam00 1.36 0.0432 55CIN5_H2O2Hi WT Durant06 -1.36 0.0432 73XBP1_H2O2Lo elp3D Durant06 -1.36 0.0432 52

FKH2_YPD SPT3 Ingvarsdottir05 1.36 0.0432 109YAP6_H2O2Hi htz1_del Mizuguch04 -1.36 0.0433 78SWI6_YPD hmr Meneghini03 -1.36 0.0434 150DIG1_BUT14 gcn5D_taf1-ts2Durant06 1.36 0.0434 57HAP4_YPD RPD3_haploid Hughes00 1.36 0.0434 67MCM1_YPD sin3 Fazzio01 1.36 0.0434 73YAP6_YPD SWR1 Krogan04 -1.36 0.0435 86RCS1_H2O2Hi isw2_c.i. Fazzio01 -1.36 0.0435 50YAP7_H2O2Hi rpd3_c.i. Fazzio01 -1.36 0.0435 137ACE2_YPD spt10_del Xu05 1.36 0.0435 80CBF1_SM sas3D_taf1-ts2Durant06 1.36 0.0436 245RCS1_H2O2Loisw2_sin3 Fazzio01 1.36 0.0436 253GCN4_RAPA taf1-ts2_25C Huisinga04 1.35 0.0437 148RCS1_H2O2LoRpd3_del Bernstein02 1.35 0.0437 253SKN7_YPD ISW1 Hughes00 1.35 0.0438 65STE12_YPD hht2_K49141823GMartin04 -1.35 0.0438 43GCN4_RAPA VID21 Krogan04 -1.35 0.0438 147SKN7_H2O2Hi htz1 Meneghini03 1.35 0.0438 98RPN4_H2O2Loisw2_rpd3 Fazzio01 1.35 0.0438 97MGA1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -1.35 0.0438 60ABF1_YPD swi1_minimal_medium_experimentSudarsanam00 -1.35 0.044 267GLN3_RAPA WT_V71R Chitikila_02 -1.35 0.044 63YAP6_H2O2Lo ARD1 Hughes00 -1.35 0.044 58GCN4_YPD WT_WT Chitikila_02 -1.35 0.044 74DAL81_RAPA sir4 Orlandi04 -1.35 0.0441 69PUT3_H2O2Lo DM_vs._YPH250Rosaleny05 1.35 0.0441 80RIM101_H2O2LoSPT8 Ingvarsdottir05 -1.35 0.0441 50SKN7_H2O2LoH3KQ Sabet04 1.35 0.0441 177XBP1_H2O2Lo VID21 Krogan04 1.35 0.0441 62AFT2_H2O2Lo delta_ssd1 Kaeberlein04 1.35 0.0442 98PUT3_H2O2Lo Dsin3 Keogh05 1.35 0.0442 76REB1_YPD TUP1_haploid Hughes00 -1.35 0.0443 139STE12_BUT14 taf1-ts2_SPT3 Huisinga04 1.35 0.0443 124SKN7_H2O2Losnf2_minimal_medium_experimentSudarsanam00 -1.35 0.0444 185YAP7_H2O2Lo SWR1 Krogan04 1.35 0.0444 136STE12_BUT14 PCH1 Hughes00 -1.35 0.0444 127DAL82_RAPA DT_V161E Chitikila_02 -1.35 0.0445 48GCN4_RAPA WT_V161R_L Chitikila_02 -1.35 0.0445 157PUT3_H2O2Lo HAT2 Hughes00 1.35 0.0445 88NDD1_YPD Ddep1 Keogh05 1.35 0.0445 80OAF1_YPD Drco1 Keogh05 1.35 0.0445 55SKN7_H2O2HiWT_Null_K Chitikila_02 -1.34 0.0447 94STE12_BUT90 rpd3_H4KQ_v_H4KQSabet04 -1.34 0.0447 74GCN4_RAPA taf1-ts2_gcn5 Huisinga04 1.34 0.0448 155HSF1_H2O2Hi DT_V71R Chitikila_02 1.34 0.0448 122FKH2_YPD WT_V71E Chitikila_02 -1.34 0.0448 109MGA1_YPD Set1_del Bernstein02 -1.34 0.0448 59SWI5_YPD SWC6_(VPS71)Krogan04 1.34 0.0449 92SWI5_YPD isw2_sin3_vs._sin3Fazzio01 -1.34 0.0449 94MSN4_H2O2HiDsap30 Keogh05 1.34 0.045 65YAP6_H2O2Lo TAF2 Mnaimneh_04 -1.34 0.045 59PHD1_BUT90 SIR2 Hughes00 1.34 0.045 106PHD1_BUT90 WT_V161R_L Chitikila_02 -1.34 0.045 104

NDD1_YPD gcn5D_taf1-ts2Durant06 1.34 0.045 81STE12_YPD gcn5 Huisinga04 -1.34 0.0451 48YAP6_H2O2Lo Drpd3 Keogh05 -1.34 0.0451 51UME6_H2O2HiSWC6_(VPS71)Krogan04 1.34 0.0452 84NDD1_YPD hht2_K27G Martin04 1.34 0.0452 75REB1_H2O2Hi SSD1-V Kaeberlein04 -1.34 0.0453 58MBP1_YPD SWR1 Krogan04 1.34 0.0453 121DAL82_SM isw2_rpd3_vs._rpd3Fazzio01 -1.34 0.0454 50MSN4_RAPA 0.1%_MMS Attikum04 1.34 0.0454 39HSF1_H2O2Hi hht2_K4G Martin04 1.34 0.0454 98REB1_H2O2Hi sir4 Orlandi04 1.34 0.0454 44REB1_H2O2Hi htz1 Meneghini03 -1.34 0.0454 54CIN5_H2O2Lo ubp10sir4 Orlandi04 -1.34 0.0454 70HSF1_H2O2Loume6 Fazzio01 1.34 0.0454 97PUT3_H2O2Lo WT_TAF1_SPT3Huisinga04 1.34 0.0454 81RCS1_H2O2Loarp8_+_0.1%_MMS_vs._arp8Attikum04 -1.34 0.0454 205YAP6_H2O2Lo BUR6 Geisberg_01 1.34 0.0454 52HSF1_H2O2Hi TUP1_haploid Hughes00 -1.34 0.0455 122AFT2_H2O2Lo EAF5 Krogan04 1.34 0.0456 81FKH1_YPD _SWC2_(VPS72)Krogan04 1.34 0.0456 135UME6_YPD rpd3_del Sabet04 1.34 0.0457 129REB1_YPD ISW1_ISW2 Hughes00 -1.33 0.0458 143SKN7_YPD H4KQ Sabet04 1.33 0.0458 62XBP1_H2O2Lo WT_V161R_L Chitikila_02 1.33 0.0458 65FKH1_YPD WT Durant06 1.33 0.0458 136DAL82_SM hos2_del Bernstein_00_affydeletions-1.33 0.0459 48MBP1_H2O2Losas3D Durant06 -1.33 0.0459 45YAP7_H2O2Lo taf1-ts2_SPT3 Huisinga04 1.33 0.046 144YAP1_YPD sir2 Meneghini03 1.33 0.0461 66RTG3_RAPA sir2 Meneghini03 1.33 0.0461 49STE12_BUT14 SWC6_(VPS71)Krogan04 1.33 0.0461 119GCN4_YPD WT_V71R Chitikila_02 -1.33 0.0461 71HAP1_YPD rpd3 Fazzio01 -1.33 0.0461 136RLM1_YPD WT Durant06 -1.33 0.0462 49YAP6_YPD YNG2 Mnaimneh_04 1.33 0.0462 91RTG3_RAPA VID21 Krogan04 1.33 0.0462 44REB1_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 -1.33 0.0462 50ASH1_BUT14 DM_vs._YPH250Rosaleny05 1.33 0.0462 45MBP1_H2O2HiDeaf3 Keogh05 1.33 0.0463 121RIM101_H2O2Losir2 Meneghini03 1.33 0.0463 53RIM101_H2O2LoWT_Null_K Chitikila_02 -1.33 0.0463 53YAP1_YPD esa1-414_taf1-ts2Durant06 1.33 0.0464 67YAP7_H2O2Hi isw2_sin3 Fazzio01 -1.33 0.0464 137MGA1_YPD rpd3_H4KQ_v_H4KQSabet04 -1.33 0.0464 61SWI4_YPD Set1_del Bernstein02 -1.33 0.0465 154MSN4_H2O2Hiswi1_minimal_medium_experimentSudarsanam00 1.33 0.0465 70MSN4_H2O2Higcn5 Huisinga04 1.33 0.0465 67PHD1_BUT90 rpd3_H3dN_v_H3dNSabet04 1.33 0.0465 96SUT1_YPD snf2_rich_medium_experimentSudarsanam00 1.33 0.0466 69MSN4_RAPA ino80_+_0.1%_MMS_vs._ino80Attikum04 1.33 0.0466 40RCS1_H2O2Hi H3KQ Sabet04 1.33 0.0466 50REB1_H2O2Hi hos2_del Bernstein_00_affydeletions1.33 0.0466 56PUT3_H2O2Lo gcn5_KQL Huisinga04 1.33 0.0466 77

FKH1_YPD ISW1_ISW2 Hughes00 -1.33 0.0466 141PHO4_YPD isw2_ume6 Fazzio01 1.33 0.0467 71SUT1_YPD WT_V161R_L Chitikila_02 -1.33 0.0467 66YAP6_H2O2Hi hat1D_taf1-ts2Durant06 -1.33 0.0467 58YAP7_H2O2Lo WT_WT Chitikila_02 1.33 0.0467 142ROX1_YPD DT_V71E Chitikila_02 -1.32 0.0468 64GCN4_RAPA DT_Null Chitikila_02 -1.32 0.0468 156AFT2_H2O2Hi isw2_c.i. Fazzio01 -1.32 0.0468 58YAP7_H2O2Hi DT_Null Chitikila_02 1.32 0.0468 133AFT2_H2O2Lo EAF7 Krogan04 1.32 0.0468 87RLM1_YPD EAF5 Krogan04 1.32 0.0469 49UME6_YPD ISW2 Hughes00 -1.32 0.0469 129MSN4_H2O2HiWT_TAF1_GCN5Huisinga04 -1.32 0.0469 69AFT2_H2O2Lo rpd3_c.i. Fazzio01 -1.32 0.0469 95ASH1_BUT14 DT_V71E Chitikila_02 -1.32 0.0469 47MSN4_H2O2Hiarp8_+_0.1%_MMS_vs._arp8Attikum04 1.32 0.047 59MCM1_Alpha SAP30 Hughes00 1.32 0.047 106FKH1_YPD isw2_sin3_vs._sin3Fazzio01 -1.32 0.0471 139DAL81_RAPA DT_V71R Chitikila_02 1.32 0.0472 93AFT2_H2O2Lo ARP4 Mnaimneh_04 1.32 0.0472 98SWI5_YPD WT_F182V Chitikila_02 1.32 0.0473 78SWI5_YPD H3_1-28 Sabet04 1.32 0.0473 93STE12_BUT14 H4_2-26 Sabet04 -1.32 0.0473 122ACE2_YPD ISW1 Hughes00 1.32 0.0473 80HAP4_YPD rsc3-2 Angus-Hill_01 -1.32 0.0473 65YAP1_YPD ISW2 Hughes00 1.32 0.0474 72YAP1_YPD H4KQ Sabet04 1.32 0.0474 70FKH2_H2O2Hi sap30_del Bernstein_00_affydeletions1.32 0.0474 99RLM1_YPD sir2 Meneghini03 1.32 0.0475 51MSN4_H2O2HiTUP1_haploid Hughes00 1.32 0.0475 69STE12_Alpha YAF9 Krogan04 1.32 0.0475 108DIG1_BUT14 hat1D_taf1-ts2Durant06 1.32 0.0475 56YAP6_YPD snf2_minimal_medium_experimentSudarsanam00 -1.32 0.0476 91XBP1_H2O2Lo snf2_minimal_medium_experimentSudarsanam00 1.32 0.0476 68REB1_YPD SWD2 Mnaimneh_04 -1.32 0.0477 145YAP6_H2O2Lo hht2_K4G Martin04 -1.32 0.0477 36DIG1_Alpha MED2_haploid Hughes00 1.32 0.0477 60ROX1_YPD Drxt2 Keogh05 -1.32 0.0478 65SWI5_YPD UBP8 Ingvarsdottir05 1.32 0.0478 90SKN7_YPD WT_V161R_L Chitikila_02 -1.31 0.0479 65GCN4_SM DT_N69R Chitikila_02 1.31 0.0479 176MBP1_YPD hmr Meneghini03 -1.31 0.0479 130AFT2_H2O2Hi ISW2 Hughes00 -1.31 0.048 61REB1_H2O2Hi PCH1 Hughes00 -1.31 0.048 58SOK2_BUT14 UBP8 Ingvarsdottir05 1.31 0.048 66UME6_H2O2Hispt10_del Xu05 -1.31 0.0481 99AFT2_H2O2Hi rsc3-2 Angus-Hill_01 1.31 0.0482 59CIN5_H2O2Hi ISW2 Hughes00 -1.31 0.0483 79FKH1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.31 0.0483 116FKH2_YPD ISW1 Hughes00 1.31 0.0484 120NDD1_YPD BUR6 Geisberg_01 1.31 0.0484 79DAL82_RAPA hpa2D Durant06 1.31 0.0485 42MSN4_RAPA ubp10sir4 Orlandi04 1.31 0.0485 27

STE12_BUT90 YAF9 Krogan04 1.31 0.0485 75YAP1_YPD delta_ssd1 Kaeberlein04 1.31 0.0486 71ABF1_YPD SAP30 Hughes00 1.31 0.0487 262STE12_BUT90 WT_Null_L Chitikila_02 1.31 0.0487 74UME6_YPD SWR1 Krogan04 1.31 0.0488 111CIN5_H2O2Hi hht2_K49141823GMartin04 1.31 0.0488 54PHD1_BUT90 TAF2 Mnaimneh_04 1.31 0.0488 106AFT2_H2O2Hi spt3 Huisinga04 -1.3 0.049 59DIG1_BUT14 TUP1_haploid Hughes00 -1.3 0.049 62MCM1_YPD HTZ1 Krogan04 1.3 0.0492 74PHD1_YPD UBP8 Ingvarsdottir05 1.3 0.0493 61STP1_SM SIN3 Hughes00 -1.3 0.0493 68MBP1_H2O2Hihht2_K27G Martin04 1.3 0.0493 108YAP1_YPD hht2_K4914182327GMartin04 -1.3 0.0494 62STP1_SM arp8 Attikum04 -1.3 0.0494 45CIN5_H2O2Hi sin3_del Bernstein_00_affydeletions-1.3 0.0494 69NRG1_H2O2HiDrxt2 Keogh05 -1.3 0.0494 119HSF1_H2O2LoDT_V161E Chitikila_02 -1.3 0.0494 98SOK2_BUT14 DM_vs._YPH250Rosaleny05 1.3 0.0494 61STE12_YPD delta_ssd1 Kaeberlein04 1.3 0.0495 52TYE7_YPD Dpho23 Keogh05 1.3 0.0495 55RIM101_H2O2LoWT_V71R Chitikila_02 1.3 0.0495 46ACE2_YPD UBP8 Ingvarsdottir05 1.3 0.0495 75MSN4_H2O2HiMED2_haploid Hughes00 1.3 0.0496 69SKN7_H2O2Hi YAF9 Krogan04 1.3 0.0496 92CIN5_YPD TAF2 Mnaimneh_04 1.3 0.0497 150AFT2_H2O2Lo taf1-ts2_25C Huisinga04 -1.3 0.0497 95MBP1_H2O2LoWT_WT Chitikila_02 -1.3 0.0497 54SKN7_H2O2Loume6 Fazzio01 -1.3 0.0497 181GCN4_SM H4KQ Sabet04 1.3 0.0498 185GCN4_YPD DT_V161R_K Chitikila_02 -1.3 0.0498 73DAL82_SM hat2_vs._YPH250Rosaleny05 1.3 0.0499 49MSN4_RAPA sin3 Fazzio01 -1.3 0.0499 53FKH2_H2O2Hi hos3_del Bernstein_00_affydeletions-1.3 0.0499 101MGA1_YPD Ddep1 Keogh05 -1.3 0.0499 58MSN4_RAPA hat1D_taf1-ts2Durant06 1.3 0.05 45CIN5_H2O2Hi swi1_rich_medium_experimentSudarsanam00 1.3 0.05 80RPN4_H2O2Loisw2_sin3_vs._sin3Fazzio01 1.3 0.05 97XBP1_H2O2Lo swr1 Meneghini03 -1.3 0.05 52STE12_Alpha ume6 Fazzio01 -1.3 0.05 112SOK2_BUT14 SAP30 Hughes00 -1.3 0.05 71DIG1_Alpha Drpd3 Keogh05 -1.3 0.0501 56REB1_YPD hat2_vs._YPH250Rosaleny05 1.29 0.0502 142SWI4_YPD sap30_del Bernstein_00_affydeletions1.29 0.0502 142MSN4_H2O2Hiset1 Boa03 1.29 0.0502 70HSF1_H2O2LoDrpd3 Keogh05 1.29 0.0502 92NRG1_YPD Drpd3 Keogh05 -1.29 0.0502 62SWI6_YPD swr1 Meneghini03 1.29 0.0503 121FKH2_H2O2Hi sir2 Meneghini03 -1.29 0.0504 106YAP7_H2O2Hi SSD1-V Kaeberlein04 1.29 0.0504 141RPN4_H2O2Lodelta_ssd1 Kaeberlein04 1.29 0.0504 100DIG1_Alpha SIR2 Hughes00 -1.29 0.0505 60ACE2_YPD Rpd3_del Bernstein02 1.29 0.0505 78

MCM1_YPD htz1_del Mizuguch04 1.29 0.0505 76STE12_BUT90 HDA1 Hughes00 -1.29 0.0506 78HSF1_H2O2Hi Deaf3 Keogh05 1.29 0.0507 112YAP6_H2O2Hi taf1-ts2_GCN5Huisinga04 -1.29 0.0507 72FKH2_YPD ISW1_ISW2 Hughes00 1.29 0.0507 121NRG1_YPD Dume1 Keogh05 -1.29 0.0507 67AFT2_H2O2Hi MOT1-14 Dasgupta02 1.29 0.0508 61PHD1_BUT90 DT_V71R Chitikila_02 1.29 0.0508 103HAP4_YPD ume6 Fazzio01 1.29 0.0508 64GCN4_YPD DT_V161E Chitikila_02 -1.29 0.0509 74ABF1_YPD 0.1%_MMS Attikum04 -1.29 0.051 233SUM1_YPD gcn5D_taf1-ts2Durant06 -1.29 0.051 47GCR2_SM hht2_K914182327GMartin04 -1.29 0.051 46REB1_H2O2Hi isw2_ume6 Fazzio01 -1.29 0.051 57AFT2_H2O2Lo htz1_sir2 Meneghini03 1.29 0.051 95DIG1_Alpha Dpho23 Keogh05 -1.29 0.051 59NRG1_H2O2Hiarp8_+_0.1%_MMS_vs._arp8Attikum04 -1.29 0.0511 87UME6_H2O2HiRSC8 Mnaimneh_04 1.29 0.0511 102FKH2_YPD gcn5D Durant06 -1.29 0.0511 101CIN5_YPD ino80 Attikum04 -1.29 0.0512 117CIN5_H2O2Lo swi1_minimal_medium_experimentSudarsanam00 -1.29 0.0512 127SKN7_H2O2LoIOC4 Hughes00 -1.29 0.0512 184GCN4_YPD sap30_del Bernstein_00_affydeletions1.29 0.0512 73HAP1_YPD swr1_del Mizuguch04 -1.29 0.0512 141GLN3_RAPA WT_V161R_K Chitikila_02 -1.28 0.0513 64DAL82_SM isw2_rpd3 Fazzio01 -1.28 0.0514 50OAF1_YPD Ddep1 Keogh05 1.28 0.0514 53STE12_YPD gcn5_KQL Huisinga04 -1.28 0.0515 43CIN5_YPD H3_1-28 Sabet04 1.28 0.0515 144GCR2_SM snf2_minimal_medium_experimentSudarsanam00 -1.28 0.0515 54YAP6_H2O2Hi WT_N69S Chitikila_02 1.28 0.0515 71SOK2_BUT14 HDA1 Hughes00 1.28 0.0515 72REB1_YPD sir2 Meneghini03 -1.28 0.0516 137REB1_H2O2Hi sin3_del Bernstein_00_affydeletions1.28 0.0516 56STE12_Alpha swi1_rich_medium_experimentSudarsanam00 -1.28 0.0516 114STE12_BUT14 taf1-ts2_spt3 Huisinga04 -1.28 0.0516 122MSN2_H2O2Hihpa2D Durant06 -1.28 0.0517 69CIN5_H2O2Lo SIR2 Hughes00 1.28 0.0517 126RPN4_H2O2Lohat1D Durant06 1.28 0.0517 82STE12_BUT14 sas3D_taf1-ts2Durant06 1.28 0.0517 113NRG1_H2O2Hiisw2_sin3 Fazzio01 -1.28 0.0518 123GCR2_SM gcn5D Durant06 1.28 0.0519 50REB1_H2O2Hi SIN3 Hughes00 1.28 0.0519 59STE12_Alpha MED2_haploid Hughes00 -1.28 0.0519 114PHD1_YPD ume6_del Bernstein_00_affydeletions1.28 0.052 60YAP7_H2O2Hi hat1_vs.YPH250Rosaleny05 1.28 0.052 140XBP1_H2O2Lo esa1-414_taf1-ts2Durant06 1.28 0.052 54NDD1_YPD WT_TAF1_SPT3Huisinga04 1.28 0.052 82SUT1_YPD WT_Null_L Chitikila_02 1.28 0.0521 64MSN2_H2O2HiSGF11 Ingvarsdottir05 1.28 0.0521 67YAP6_H2O2Hi spt10_del Xu05 -1.28 0.0521 78SOK2_BUT14 PCH1 Hughes00 -1.28 0.0521 72NRG1_YPD taf1-ts2_GCN5Huisinga04 -1.28 0.0522 66

GCR2_SM DT_V161E Chitikila_02 -1.28 0.0523 54MSN2_H2O2HiWT_WT Chitikila_02 1.28 0.0523 76ROX1_YPD WT_V71E Chitikila_02 1.28 0.0524 57DAL82_SM rpd3_c.i. Fazzio01 -1.28 0.0524 50YAP6_H2O2Lo hos2_del Bernstein_00_affydeletions-1.28 0.0524 50ACE2_YPD EAF7 Krogan04 1.28 0.0524 78RLM1_YPD DT_V71E Chitikila_02 -1.27 0.0525 52SWI6_YPD ubp10sir4 Orlandi04 -1.27 0.0527 110GLN3_RAPA WT_N69R Chitikila_02 -1.27 0.0527 65YAP6_H2O2Lo EAF5 Krogan04 1.27 0.0527 54STE12_BUT90 WT_V71R Chitikila_02 -1.27 0.0529 69FKH2_YPD taf1-ts2_gcn5_KQLHuisinga04 -1.27 0.0529 103MSN4_RAPA SIR1 Hughes00 -1.27 0.053 53YAP6_H2O2Hi htz1_sir2 Meneghini03 1.27 0.053 78YAP7_H2O2Hi sin3 Fazzio01 -1.27 0.053 137DAL82_RAPA YNG2 Mnaimneh_04 1.27 0.0531 56PHO4_YPD EAF7 Krogan04 -1.27 0.0532 69REB1_H2O2Hi HIR2 Hughes00 1.27 0.0533 59PUT3_H2O2Lo hat2_vs._hat1Rosaleny05 1.27 0.0533 87DIG1_BUT14 hht2K9131823GMartin04 1.27 0.0533 55RCS1_H2O2Lospt10_del Xu05 1.27 0.0534 249ACE2_YPD WT_V161R_K Chitikila_02 -1.27 0.0534 75PHD1_YPD DT_V71R Chitikila_02 1.27 0.0536 65SUM1_YPD hpa2D Durant06 -1.27 0.0536 36PHD1_BUT90 SWC6_(VPS71)Krogan04 1.27 0.0536 94DAL82_RAPA sin3 Fazzio01 -1.27 0.0537 54SKN7_H2O2Hi spt10_del Xu05 1.26 0.0539 95UME6_H2O2Higcn5 Huisinga04 1.26 0.0539 97SKN7_H2O2LoHDA1 Hughes00 1.26 0.0539 183GLN3_RAPA hat1D Durant06 -1.26 0.054 46RTG3_RAPA hht2_K914182327GMartin04 1.26 0.054 43YAP7_H2O2Lo RPD3_haploid Hughes00 1.26 0.054 149RTG3_RAPA taf1-ts2_gcn5 Huisinga04 1.26 0.0541 51HSF1_H2O2Hi delta_ssd1 Kaeberlein04 1.26 0.0541 124NDD1_YPD sap30_del Bernstein_00_affydeletions1.26 0.0541 81SUM1_YPD elp3D_taf1-ts2Durant06 -1.26 0.0542 41MSN4_RAPA hht2K9131823GMartin04 -1.26 0.0542 36HSF1_H2O2Hi taf1-ts2_25C Huisinga04 1.26 0.0542 106HSF1_H2O2LoTUP1_haploid Hughes00 -1.26 0.0542 99HAP4_YPD SIR4 Hughes00 -1.26 0.0542 67YAP1_YPD hat1_vs.YPH250Rosaleny05 1.26 0.0544 70NRG1_H2O2Hihht2_K27G Martin04 -1.26 0.0544 81REB1_H2O2Hi YNG2 Mnaimneh_04 -1.26 0.0544 59NRG1_YPD DT_V161R_L Chitikila_02 1.26 0.0544 65SUT1_YPD rpd3_del Sabet04 -1.26 0.0545 66CIN5_H2O2Lo hht2_K49141823GMartin04 1.26 0.0545 87XBP1_H2O2Lo isw2_rpd3 Fazzio01 -1.26 0.0545 65YAP7_H2O2Lo ISW2 Hughes00 1.26 0.0545 152OAF1_YPD WT_N69R Chitikila_02 -1.26 0.0545 54SWI5_YPD hat1D_taf1-ts2Durant06 1.26 0.0546 78SWI6_YPD spt3_E240K Huisinga04 -1.26 0.0547 136SKN7_H2O2LoRpd3_del Bernstein02 1.26 0.0547 183GCR2_SM isw2_c.i. Fazzio01 -1.26 0.0548 52

YAP6_H2O2Hi SIR1 Hughes00 1.26 0.0548 77MCM1_Alpha esa1-414_taf1-ts2Durant06 1.26 0.0548 96STE12_BUT90 gcn5 Huisinga04 -1.26 0.0548 76PHD1_YPD H4_2-26 Sabet04 1.26 0.0549 62ABF1_YPD rpd3_del Sabet04 -1.25 0.055 260TYE7_YPD rpd3_c.i. Fazzio01 -1.25 0.055 54GCN4_YPD htz1_del Mizuguch04 1.25 0.055 75STP1_SM taf1-ts2_25C Huisinga04 1.25 0.0551 62GCN4_RAPA ARP4 Mnaimneh_04 1.25 0.0551 160PHD1_BUT90 H4_2-26 Sabet04 1.25 0.0551 96MGA1_YPD Dpho23 Keogh05 -1.25 0.0551 63ABF1_YPD VID21 Krogan04 -1.25 0.0553 246TYE7_YPD gcn5_KQL Huisinga04 -1.25 0.0554 44GCR2_SM DT_V71E Chitikila_02 -1.25 0.0554 54DAL81_RAPA spt10 Eriksson05 -1.25 0.0554 95REB1_H2O2Hi EAF5 Krogan04 -1.25 0.0555 54PUT3_H2O2Lo IOC4 Hughes00 -1.25 0.0555 87SOK2_BUT14 isw2 Fazzio01 -1.25 0.0555 71SKN7_YPD DT_V161E Chitikila_02 -1.25 0.0556 65DAL82_RAPA Dsin3 Keogh05 -1.25 0.0556 46YAP7_H2O2Lo WT_V161E Chitikila_02 -1.25 0.0556 145UME6_YPD hht2_K27G Martin04 1.25 0.0557 90PHD1_BUT90 IES6 Hughes00 1.25 0.0557 106SWI6_YPD WT_Null_L Chitikila_02 1.25 0.0558 146UME6_H2O2Hiesa1-414 Durant06 1.25 0.0558 92YAP6_H2O2Lo WT_V71E Chitikila_02 -1.25 0.0558 50YAP7_H2O2Lo MOT1-42 Dasgupta02 1.25 0.0558 150HAP4_YPD IOC4 Hughes00 1.25 0.0558 66HAP4_YPD YNG2 Mnaimneh_04 1.25 0.0558 67ROX1_YPD swi1_minimal_medium_experimentSudarsanam00 1.25 0.056 67CIN5_H2O2Hi DM_vs._YPH250Rosaleny05 1.25 0.056 72NRG1_YPD BUR6 Geisberg_01 1.25 0.056 62MSN4_H2O2Hihht2_K49141823GMartin04 1.25 0.0561 59MCM1_Alpha esa1-414 Durant06 1.25 0.0561 95ACE2_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.25 0.0561 65GCR2_SM DM_vs._YPH250Rosaleny05 1.25 0.0562 50DAL81_RAPA ISW1 Hughes00 -1.25 0.0562 95RTG3_RAPA taf1-ts2_spt3 Huisinga04 1.25 0.0562 49CIN5_H2O2Hi hos3_del Bernstein_00_affydeletions-1.25 0.0562 68HSF1_H2O2LoYAF9 Krogan04 1.25 0.0562 98HAP1_YPD taf1-ts2_spt3 Huisinga04 1.25 0.0562 135CIN5_H2O2Hi htz1_del Mizuguch04 -1.24 0.0563 80MSN4_H2O2HiSWR1 Krogan04 1.24 0.0563 60STE12_BUT14 DT_V71R Chitikila_02 -1.24 0.0563 120MBP1_YPD hht2_K4G Martin04 1.24 0.0563 115GLN3_RAPA ARP4 Mnaimneh_04 1.24 0.0564 68MCM1_Alpha ARD1 Hughes00 -1.24 0.0564 106OAF1_YPD ume6_del Bernstein_00_affydeletions-1.24 0.0564 52UME6_YPD ISW1_ISW2 Hughes00 1.24 0.0565 129GCN4_SM DT_V161E Chitikila_02 -1.24 0.0566 180FKH2_H2O2Hi SPT3 Ingvarsdottir05 1.24 0.0566 100UME6_H2O2HiDT_Null Chitikila_02 1.24 0.0566 96YAP6_YPD WT_F182V Chitikila_02 -1.24 0.0567 77

DAL82_RAPA taf1-ts2_SPT3 Huisinga04 1.24 0.0567 53MBP1_H2O2Loisw2_rpd3_vs._rpd3Fazzio01 1.24 0.0567 54GLN3_RAPA Ddep1 Keogh05 -1.24 0.0568 64DAL81_RAPA gcn5_KQL Huisinga04 1.24 0.0569 82CIN5_H2O2Hi DT_V161R_K Chitikila_02 1.24 0.0569 79NRG1_H2O2HiISW1_ISW2 Hughes00 -1.24 0.057 126YAP6_H2O2Hi SWC6_(VPS71)Krogan04 -1.24 0.057 75YAP7_H2O2Lo gcn5D_taf1-ts2Durant06 1.24 0.057 139ABF1_YPD rpd3_H3dN_v_H3dNSabet04 -1.24 0.0572 260SWI5_YPD taf1-ts2_spt3_E240KHuisinga04 1.24 0.0572 84SWI5_YPD htz1_del Mizuguch04 1.24 0.0572 101CIN5_YPD swi1_minimal_medium_experimentSudarsanam00 -1.24 0.0573 150REB1_H2O2Hi htz1_sir2 Meneghini03 -1.24 0.0573 55PHD1_BUT90 elp3D_taf1-ts2Durant06 1.24 0.0573 73GLN3_RAPA DT_V161E Chitikila_02 -1.24 0.0574 63YAP6_H2O2Hi DT_V161R_K Chitikila_02 1.24 0.0574 76ROX1_YPD DT_V161E Chitikila_02 1.23 0.0576 65TYE7_YPD taf1-ts2_gcn5_KQLHuisinga04 -1.23 0.0576 44STP1_SM Dsap30 Keogh05 -1.23 0.0576 61STE12_BUT90 taf1-ts2_spt3 Huisinga04 -1.23 0.0576 73SWI4_YPD swr1_del Mizuguch04 1.23 0.0577 154SWI4_YPD H3_1-28 Sabet04 -1.23 0.0577 151STE12_Alpha WT_F182V Chitikila_02 1.23 0.0577 91STE12_BUT90 WT_V71E Chitikila_02 -1.23 0.0577 63NDD1_YPD elp3D_taf1-ts2Durant06 1.23 0.0577 76UME6_YPD sir2 Meneghini03 1.23 0.0578 128FKH2_YPD DT_V161E Chitikila_02 -1.23 0.0578 112RLM1_YPD elp3D_taf1-ts2Durant06 1.23 0.0579 44ROX1_YPD isw2_rpd3 Fazzio01 -1.23 0.0579 66NRG1_YPD WT_V71E Chitikila_02 -1.23 0.0579 56ROX1_YPD sin3 Fazzio01 -1.23 0.058 67DAL82_SM ZDS1 Hughes00 1.23 0.058 55AFT2_H2O2Hi SIR2 Hughes00 1.23 0.058 61PHO4_YPD isw2 Fazzio01 1.23 0.0581 71MSN4_RAPA sas3D_taf1-ts2Durant06 1.23 0.0581 46UME6_H2O2HiMED2_haploid Hughes00 -1.23 0.0581 101STE12_Alpha isw2_rpd3 Fazzio01 -1.23 0.0581 112SUM1_YPD DT_V161R_K Chitikila_02 1.23 0.0582 54NRG1_H2O2HiDrco1 Keogh05 1.23 0.0582 116YAP7_H2O2Hi Deaf3 Keogh05 -1.23 0.0582 130XBP1_H2O2Lo H4_2-26 Sabet04 1.23 0.0582 56CIN5_H2O2Lo taf1-ts2_spt3 Huisinga04 -1.23 0.0583 117MBP1_H2O2Losas3D_taf1-ts2Durant06 -1.23 0.0583 53CIN5_H2O2Hi isw2_rpd3 Fazzio01 -1.23 0.0584 79MCM1_Alpha ume6 Fazzio01 1.23 0.0584 104PHD1_YPD taf1-ts2_gcn5_KQLHuisinga04 1.23 0.0585 59STE12_YPD hht2K9131823GMartin04 -1.23 0.0585 43DAL82_RAPA esa1-414_taf1-ts2Durant06 1.23 0.0585 46HSF1_H2O2Hi swi1_rich_medium_experimentSudarsanam00 1.23 0.0585 124NRG1_YPD gcn5D_taf1-ts2Durant06 -1.23 0.0585 62TYE7_YPD swi1_minimal_medium_experimentSudarsanam00 -1.23 0.0586 55REB1_H2O2Hi snf2_rich_medium_experimentSudarsanam00 -1.23 0.0587 58RCS1_H2O2Lohht2_K914182327GMartin04 1.23 0.0587 219

UME6_YPD WT_V161E Chitikila_02 -1.23 0.0588 117UME6_H2O2HiDT_V161R_K Chitikila_02 1.23 0.0588 98TYE7_YPD EAF5 Krogan04 1.22 0.0589 49NRG1_H2O2Hihat2_vs._YPH250Rosaleny05 -1.22 0.0589 114MBP1_H2O2Loswi1_minimal_medium_experimentSudarsanam00 1.22 0.059 57MBP1_H2O2LoWT_V161R_K Chitikila_02 -1.22 0.059 52RCS1_H2O2LoHDA1 Hughes00 -1.22 0.059 255DIG1_Alpha sin3 Fazzio01 -1.22 0.059 59ACE2_YPD htz1 Meneghini03 1.22 0.059 80GCR2_SM MOT1-42 Dasgupta02 -1.22 0.0591 54MSN4_H2O2Hihtz1 Meneghini03 1.22 0.0591 69SKN7_H2O2LoWT_TAF1_GCN5Huisinga04 -1.22 0.0592 181DIG1_Alpha ARP4 Mnaimneh_04 1.22 0.0592 60SWI5_YPD WT_V161R_K Chitikila_02 -1.22 0.0593 90UME6_YPD SAP30 Hughes00 1.22 0.0593 130YAP1_YPD TUP1_haploid Hughes00 1.22 0.0594 71MBP1_YPD Dsds3 Keogh05 1.22 0.0594 125CIN5_H2O2Hi swr1 Meneghini03 -1.22 0.0595 63YAP6_H2O2Hi Ddep1 Keogh05 -1.22 0.0595 75AFT2_H2O2Lo rpd3_del Sabet04 -1.22 0.0595 92ABF1_YPD gcn5_KQL Huisinga04 1.22 0.0596 249RLM1_YPD WT_WT Chitikila_02 -1.22 0.0596 50CBF1_SM Dume1 Keogh05 1.22 0.0596 246AFT2_H2O2Hi spt3_E240K Huisinga04 -1.22 0.0596 51SKN7_H2O2Hi rpd3_c.i. Fazzio01 -1.22 0.0596 95XBP1_H2O2Lo ino80_+_0.1%_MMS_vs._ino80Attikum04 -1.22 0.0596 41STE12_BUT90 DT_V161R_K Chitikila_02 -1.22 0.0596 73UME6_H2O2HiDT_N69S Chitikila_02 1.22 0.0598 87REB1_H2O2Hi MED2_haploid Hughes00 1.22 0.0599 59FKH1_YPD rsc30_null Angus-Hill_01 1.22 0.0599 139RTG3_RAPA ubp10 Orlandi04 -1.22 0.06 34CIN5_YPD Drxt1 Keogh05 -1.22 0.0601 146RPN4_H2O2LoEPL1 Mnaimneh_04 1.22 0.0601 100DIG1_BUT14 elp3D Durant06 -1.22 0.0601 53YAP6_H2O2Hi hpa2D_taf1-ts2Durant06 -1.22 0.0602 53MSN4_RAPA taf1-ts2_spt3_E240KHuisinga04 1.21 0.0603 52MSN4_H2O2Hihht2_K4G Martin04 1.21 0.0603 59SKN7_H2O2Hi spt3 Huisinga04 -1.21 0.0604 91PHO4_YPD hat2_vs._hat1Rosaleny05 -1.21 0.0605 69SUM1_YPD hos2_del Bernstein_00_affydeletions-1.21 0.0605 43GCR2_SM hat2_vs._YPH250Rosaleny05 -1.21 0.0605 51STP1_SM DT_Null Chitikila_02 1.21 0.0605 63YAP6_H2O2Lo gcn5D Durant06 -1.21 0.0605 47PUT3_H2O2Lo hat1D Durant06 -1.21 0.0606 66DIG1_BUT14 taf1-ts2_SPT3 Huisinga04 1.21 0.0606 61HAP4_YPD isw2 Fazzio01 -1.21 0.0606 64CBF1_SM DM_vs._YPH250Rosaleny05 1.21 0.0608 248MSN4_H2O2HiDsds3 Keogh05 1.21 0.0608 66PHD1_YPD H3_1-28 Sabet04 1.21 0.0609 62SUT1_YPD TAF2 Mnaimneh_04 1.21 0.0609 69YAP6_H2O2Lo ino80_+_0.1%_MMS_vs._ino80Attikum04 -1.21 0.0609 39HSF1_H2O2Loume6_del Bernstein_00_affydeletions1.21 0.061 96FKH1_YPD RPD3_haploid Hughes00 1.21 0.061 140

FKH2_YPD hpa2D_taf1-ts2Durant06 -1.21 0.061 93GCN4_RAPA taf1-ts2_spt3 Huisinga04 -1.21 0.0611 154UME6_H2O2HiRAD6_haploid Hughes00 1.21 0.0611 100HSF1_H2O2Loubp10sir4 Orlandi04 -1.21 0.0611 77CIN5_H2O2Lo TAF2 Mnaimneh_04 1.21 0.0612 127YAP6_H2O2Lo IES6 Hughes00 -1.21 0.0612 57RTG3_RAPA MOT1-14 Dasgupta02 1.21 0.0614 51YAP6_H2O2Lo swi1_minimal_medium_experimentSudarsanam00 1.21 0.0614 58RCS1_H2O2Hi DT_V161R_K Chitikila_02 1.21 0.0615 47PHD1_BUT90 WT_V71R Chitikila_02 -1.21 0.0615 100CBF1_SM Rpd3_del Bernstein02 1.21 0.0616 273MBP1_H2O2HiDT_V161E Chitikila_02 -1.21 0.0616 123RLM1_YPD HTZ1 Krogan04 1.2 0.0617 51RIM101_H2O2Lorsc3-2 Angus-Hill_01 1.2 0.0617 52FKH1_YPD DT_V161R_L Chitikila_02 -1.2 0.0617 131SOK2_BUT14 DT_V161R_L Chitikila_02 1.2 0.0617 68STE12_Alpha sin3_del Bernstein_00_affydeletions-1.2 0.0618 104ASH1_BUT14 SIR1 Hughes00 1.2 0.0618 49NRG1_YPD SSD1-V Kaeberlein04 -1.2 0.0618 72SUT1_YPD Deaf3 Keogh05 1.2 0.0619 61FKH2_H2O2Hi spt10 Eriksson05 -1.2 0.0619 105MSN4_H2O2Hi0.1%_MMS Attikum04 1.2 0.062 60RCS1_H2O2Hi ino80_del Mizuguch04 1.2 0.062 52DAL82_RAPA SPT3 Ingvarsdottir05 -1.2 0.0621 47FKH2_YPD Deaf3 Keogh05 1.2 0.0621 111SUT1_YPD hat2_vs._hat1Rosaleny05 1.2 0.0622 61SUT1_YPD htz1_sir2 Meneghini03 1.2 0.0622 65MSN4_RAPA Dsin3 Keogh05 -1.2 0.0622 49SOK2_BUT14 taf1-ts2_gcn5_KQLHuisinga04 1.2 0.0622 57NDD1_YPD SWR1 Krogan04 1.2 0.0622 79MBP1_H2O2HiWT_V161R_K Chitikila_02 -1.2 0.0623 122HSF1_H2O2LoSIR3 Hughes00 1.2 0.0623 100SOK2_BUT14 snf2_minimal_medium_experimentSudarsanam00 -1.2 0.0623 72PHD1_YPD Dsds3 Keogh05 -1.2 0.0624 60NRG1_YPD gcn5_KQL Huisinga04 1.2 0.0624 62SWI5_YPD H4_2-26 Sabet04 1.2 0.0625 93YAP6_YPD SIR1 Hughes00 1.2 0.0625 91DAL81_RAPA HIR2 Hughes00 1.2 0.0625 94YAP7_H2O2Hi Dsds3 Keogh05 1.2 0.0625 129SOK2_BUT14 hat2_vs._YPH250Rosaleny05 1.2 0.0625 66SKN7_H2O2Loino80 Attikum04 1.2 0.0626 142MSN2_H2O2HiSWR1 Krogan04 1.2 0.0627 67HSF1_H2O2Lotaf1-ts2_25C Huisinga04 1.2 0.0627 85STE12_BUT14 ubp10 Orlandi04 -1.2 0.0628 88GCN4_SM SIN3 Hughes00 -1.2 0.0629 188RPN4_H2O2LoTAF2 Mnaimneh_04 1.2 0.0629 99GLN3_RAPA ino80_del Mizuguch04 1.19 0.0631 68STE12_YPD isw2_rpd3 Fazzio01 -1.19 0.0632 54SUM1_YPD WT_V71R Chitikila_02 1.19 0.0632 49GLN3_RAPA isw2_rpd3_vs._rpd3Fazzio01 -1.19 0.0632 67RIM101_H2O2Lotaf1-ts2_gcn5_KQLHuisinga04 1.19 0.0632 46SKN7_H2O2Lohmr Meneghini03 -1.19 0.0633 180ASH1_BUT14 SSN6_haploid Hughes00 1.19 0.0633 50

ACE2_YPD SIR2 Hughes00 1.19 0.0633 80CIN5_YPD hht2K9131823GMartin04 1.19 0.0634 115YAP6_YPD hpa2D_taf1-ts2Durant06 -1.19 0.0635 57DIG1_Alpha spt3 Huisinga04 -1.19 0.0636 53ACE2_YPD hpa2D_taf1-ts2Durant06 1.19 0.0636 60SUM1_YPD IOC4 Hughes00 1.19 0.0637 58HAP1_YPD IES6 Hughes00 1.19 0.0637 139NDD1_YPD WT_N69S Chitikila_02 -1.19 0.0637 77FKH2_YPD isw2_sin3_vs._sin3Fazzio01 -1.19 0.0638 119NDD1_YPD hpa2D_taf1-ts2Durant06 1.19 0.0638 66PHD1_YPD hat1D Durant06 -1.19 0.0639 50NRG1_H2O2HiMOT1-42 Dasgupta02 1.19 0.0639 124FKH1_YPD WT_V161R_L Chitikila_02 -1.19 0.0639 137NDD1_YPD hat1D_taf1-ts2Durant06 1.19 0.0639 75GCN4_SM isw2_rpd3 Fazzio01 1.19 0.064 183MSN2_H2O2Hirsc3-2 Angus-Hill_01 -1.19 0.064 78STE12_BUT90 SAP30 Hughes00 1.19 0.064 77YAP1_YPD isw2_sin3_vs._sin3Fazzio01 -1.19 0.0641 68REB1_YPD snf2_rich_medium_experimentSudarsanam00 -1.19 0.0642 142DAL81_RAPA SAP30 Hughes00 1.19 0.0642 95NRG1_H2O2Hi0.1%_MMS Attikum04 -1.19 0.0642 88SKN7_H2O2Hi hda1_del Bernstein_00_affydeletions1.19 0.0642 88UME6_H2O2HiDT_V71E Chitikila_02 1.19 0.0642 94CIN5_H2O2Lo arp8 Attikum04 -1.19 0.0642 90XBP1_H2O2Lo WT_N69R Chitikila_02 1.19 0.0642 59STE12_BUT90 WT_F182V Chitikila_02 1.19 0.0642 68MSN4_RAPA DT_V71E Chitikila_02 1.19 0.0643 51YAP7_H2O2Lo DT_Null Chitikila_02 1.19 0.0643 141TYE7_YPD WT_Null_K Chitikila_02 1.19 0.0644 54UME6_YPD DT_Null Chitikila_02 1.19 0.0644 122RCS1_H2O2Hi Drpd3 Keogh05 1.19 0.0644 46HAP4_YPD SIN3 Hughes00 -1.19 0.0644 67MGA1_YPD PCH1 Hughes00 -1.19 0.0644 62MSN2_H2O2HiDT_V161R_L Chitikila_02 -1.19 0.0645 75STE12_YPD hht2_K27G Martin04 -1.18 0.0646 43MBP1_H2O2HiEAF7 Krogan04 1.18 0.0646 127RPN4_H2O2LoDT_WT Chitikila_02 -1.18 0.0646 94HAP1_YPD WT_Null_K Chitikila_02 -1.18 0.0646 137TYE7_YPD hmr Meneghini03 -1.18 0.0647 54CIN5_H2O2Lo hht2_K914182327GMartin04 1.18 0.0647 83MBP1_H2O2LoWT_N69S Chitikila_02 -1.18 0.0648 53HAP4_YPD Dsin3 Keogh05 -1.18 0.0648 54ASH1_BUT14 ume6 Fazzio01 1.18 0.0649 49SOK2_BUT14 hmr Meneghini03 -1.18 0.0649 69CIN5_H2O2Hi ISW1 Hughes00 1.18 0.065 79ABF1_YPD isw2 Fazzio01 1.18 0.0651 262NRG1_H2O2HiISW1 Hughes00 1.18 0.0652 125MCM1_Alpha Hda1_del Bernstein02 1.18 0.0652 105MSN2_H2O2HiTUP1_haploid Hughes00 1.18 0.0653 76YAP7_H2O2Hi taf1-ts2_SPT3 Huisinga04 1.18 0.0653 136HAP1_YPD H4KQ Sabet04 1.18 0.0653 137REB1_YPD hht2_K27G Martin04 1.18 0.0654 125XBP1_H2O2Lo HIR2 Hughes00 1.18 0.0654 66

MBP1_YPD hht2_K49141823GMartin04 1.18 0.0654 115STE12_BUT14 UBP8 Hughes00 1.18 0.0655 127MSN2_H2O2Hirpd3_c.i. Fazzio01 -1.18 0.0656 75MCM1_Alpha hht2_K49141823GMartin04 1.18 0.0656 89SWI4_YPD hos3_del Bernstein_00_affydeletions1.18 0.0658 144PUT3_H2O2Lo swi1_minimal_medium_experimentSudarsanam00 1.18 0.0659 88YAP1_YPD rpd3_H4KQ_v_H4KQSabet04 -1.18 0.066 70SUM1_YPD WT_V71E Chitikila_02 -1.17 0.0661 47DIG1_BUT14 hmr Meneghini03 -1.17 0.0661 62OAF1_YPD sir2 Meneghini03 1.17 0.0661 59NDD1_YPD taf1-ts2_spt3_E240KHuisinga04 -1.17 0.0663 77XBP1_H2O2Lo isw2 Fazzio01 -1.17 0.0664 65REB1_YPD YNG2 Mnaimneh_04 -1.17 0.0665 144GCN4_RAPA SWR1 Krogan04 1.17 0.0665 146CIN5_H2O2Hi WT_Null_K Chitikila_02 1.17 0.0665 79YAP7_H2O2Lo HTZ1 Krogan04 1.17 0.0665 138RCS1_H2O2Hi YNG2 Mnaimneh_04 1.17 0.0667 52PUT3_H2O2Lo sin3 Fazzio01 -1.17 0.0667 86STE12_BUT14 delta_ssd1 Kaeberlein04 1.17 0.0667 128CBF1_SM ino80_del Mizuguch04 -1.17 0.0668 278STE12_BUT90 hht2K9131823GMartin04 1.17 0.0668 65NRG1_H2O2HiIES6 Hughes00 1.17 0.0669 126PHD1_BUT90 WT_V161R_K Chitikila_02 -1.17 0.0669 97PHO4_YPD sap30_del Bernstein_00_affydeletions-1.17 0.067 69YAP6_H2O2Hi ISW1_ISW2 Hughes00 -1.17 0.067 77ABF1_YPD hht2_K49141823GMartin04 1.17 0.0671 235DAL82_SM RPD3_haploid Hughes00 -1.17 0.0671 55YAP7_H2O2Hi rsc30_null Angus-Hill_01 -1.17 0.0671 137SKN7_H2O2HiDM_vs._YPH250Rosaleny05 1.17 0.0672 88STE12_Alpha DT_N69S Chitikila_02 -1.17 0.0672 98XBP1_H2O2Lo HDA1 Hughes00 1.17 0.0673 67MBP1_YPD esa1-414_taf1-ts2Durant06 1.17 0.0673 116CIN5_H2O2Hi DT_V161E Chitikila_02 -1.17 0.0674 76STP1_SM Ddep1 Keogh05 -1.17 0.0675 61YAP6_H2O2Hi htz1 Meneghini03 -1.17 0.0675 78RCS1_H2O2Lohos3_del Bernstein_00_affydeletions1.17 0.0675 247YAP7_H2O2Lo DT_V161E Chitikila_02 -1.17 0.0676 143CIN5_H2O2Hi WT_V71R Chitikila_02 1.16 0.0677 74MGA1_YPD hda1_del Bernstein_00_affydeletions-1.16 0.0677 60NRG1_H2O2HiHIR2 Hughes00 1.16 0.0678 123PHD1_BUT90 ARD1 Hughes00 -1.16 0.0678 105PHD1_BUT90 Deaf3 Keogh05 1.16 0.0678 94NDD1_YPD isw2_sin3 Fazzio01 1.16 0.0678 80HAP1_YPD HTZ1 Krogan04 1.16 0.0679 132SUT1_YPD ISW1_ISW2 Hughes00 1.16 0.068 69RTG3_RAPA sas3D Durant06 -1.16 0.068 44YAP6_H2O2Hi H4KQ Sabet04 1.16 0.068 71YAP1_YPD Rpd3_del Bernstein02 1.16 0.0681 71YAP1_YPD hpa2D_taf1-ts2Durant06 1.16 0.0682 56DAL81_RAPA Drxt1 Keogh05 1.16 0.0682 93STE12_BUT90 hos2_del Bernstein_00_affydeletions1.16 0.0682 73SWI5_YPD gcn5D Durant06 1.16 0.0683 84GCN4_SM isw2_rpd3_vs._rpd3Fazzio01 -1.16 0.0683 182

STP1_SM swi1_minimal_medium_experimentSudarsanam00 1.16 0.0683 67XBP1_H2O2Lo elp3D_taf1-ts2Durant06 -1.16 0.0683 46ASH1_BUT14 isw2 Fazzio01 1.16 0.0683 49NDD1_YPD rsc30_null Angus-Hill_01 -1.16 0.0683 82MSN4_RAPA Drxt2 Keogh05 -1.16 0.0684 49STE12_YPD swr1_del Mizuguch04 1.16 0.0685 54PHD1_BUT90 hht2_K49141823GMartin04 1.16 0.0685 79RLM1_YPD _SWC2_(VPS72)Krogan04 1.16 0.0686 55GCN4_SM rsc30_null Angus-Hill_01 -1.16 0.0686 180MSN4_RAPA IOC4 Hughes00 1.16 0.0686 53YAP7_H2O2Hi RSC8 Mnaimneh_04 1.16 0.0686 141RLM1_YPD swr1 Meneghini03 1.16 0.0687 43RPN4_H2O2Lo_SWC2_(VPS72)Krogan04 1.16 0.0687 99SKN7_H2O2LoDrxt1 Keogh05 -1.16 0.0687 184MGA1_YPD UBP8 Hughes00 -1.16 0.0687 60NDD1_YPD rpd3_H4KQ_v_H4KQSabet04 -1.16 0.0687 83STE12_Alpha gcn5 Huisinga04 -1.16 0.0688 111GCN4_YPD sin3 Fazzio01 1.16 0.0689 74NRG1_YPD WT_V161R_K Chitikila_02 1.16 0.0689 63CIN5_YPD SIR1 Hughes00 1.16 0.069 149MBP1_YPD delta_ssd1 Kaeberlein04 1.16 0.069 129SKN7_H2O2Lohtz1_hmr Meneghini03 1.16 0.0691 181MCM1_Alpha rsc3-2 Angus-Hill_01 1.16 0.0691 102DIG1_BUT14 Set1_del Bernstein02 -1.15 0.0692 63STE12_YPD UBP8 Hughes00 1.15 0.0693 54YAP6_YPD swr1_del Mizuguch04 -1.15 0.0693 91SKN7_H2O2Lohht2_K914182327GMartin04 1.15 0.0693 144PHO4_YPD VID21 Krogan04 -1.15 0.0694 66UME6_H2O2HiWT_F182V Chitikila_02 1.15 0.0694 82PHO4_YPD WT_Null_K Chitikila_02 1.15 0.0695 66ABF1_YPD WT_F182V Chitikila_02 -1.15 0.0696 228DAL81_RAPA H3_1-28 Sabet04 1.15 0.0697 94ROX1_YPD Deaf3 Keogh05 -1.15 0.0699 63STE12_YPD H3KQ Sabet04 -1.15 0.0699 51UME6_YPD TAF2 Mnaimneh_04 1.15 0.0699 131DAL82_RAPA Dsds3 Keogh05 -1.15 0.0699 52MSN4_RAPA taf1-ts2_SPT3 Huisinga04 1.15 0.0699 52MSN4_RAPA spt3 Huisinga04 1.15 0.0699 53MBP1_H2O2LoDT_V161R_L Chitikila_02 -1.15 0.0699 52YAP7_H2O2Lo hpa2D_taf1-ts2Durant06 1.15 0.0699 120ACE2_YPD IES6 Hughes00 1.15 0.0699 79STE12_YPD Drxt2 Keogh05 -1.15 0.07 54DIG1_BUT14 Drxt1 Keogh05 -1.15 0.07 63FKH1_YPD rpd3_del Sabet04 1.15 0.07 138SWI6_YPD rpd3_H4KQ_v_H4KQSabet04 -1.15 0.0701 148ROX1_YPD HAT2 Hughes00 1.15 0.0703 66YAP1_YPD Drpd3 Keogh05 1.15 0.0703 66REB1_YPD TAF2 Mnaimneh_04 1.15 0.0704 145MSN4_RAPA Drxt1 Keogh05 -1.15 0.0705 54YAP7_H2O2Hi taf1-ts2 Durant06 1.15 0.0705 141AFT2_H2O2Lo hht2_K49141823GMartin04 1.15 0.0705 67STE12_BUT90 gcn5D Durant06 -1.15 0.0705 69CIN5_H2O2Hi ino80 Attikum04 -1.15 0.0706 58

CIN5_H2O2Lo DT_V161R_L Chitikila_02 1.15 0.0706 126YAP7_H2O2Lo taf1-ts2_25C Huisinga04 -1.15 0.0706 139XBP1_H2O2Lo DT_V161E Chitikila_02 -1.15 0.0707 66ASH1_BUT14 hos2_del Bernstein_00_affydeletions1.14 0.0708 43STE12_Alpha SIR2 Hughes00 -1.14 0.0709 114PHO4_YPD WT_F182V Chitikila_02 -1.14 0.071 63STE12_YPD isw2_ume6 Fazzio01 -1.14 0.071 54MCM1_YPD HDA1 Hughes00 -1.14 0.071 77XBP1_H2O2Lo htz1_hmr Meneghini03 -1.14 0.0711 67DAL81_RAPA RSC8 Mnaimneh_04 1.14 0.0712 95PHD1_BUT90 htz1 Meneghini03 -1.14 0.0712 105GCR2_SM ARP4 Mnaimneh_04 1.14 0.0713 54ASH1_BUT14 IES6 Hughes00 -1.14 0.0713 50REB1_YPD hht2_K49141823GMartin04 1.14 0.0714 127DAL81_RAPA SPT3 Ingvarsdottir05 1.14 0.0714 79PHD1_YPD SIR2 Hughes00 1.14 0.0715 67AFT2_H2O2Hi DT_V71E Chitikila_02 -1.14 0.0715 59CBF1_SM VID21 Krogan04 1.14 0.0716 252YAP6_YPD SAP30 Hughes00 -1.14 0.0717 91NDD1_YPD taf1-ts2_spt3 Huisinga04 -1.14 0.0717 81RLM1_YPD Drxt1 Keogh05 -1.14 0.0718 54ASH1_BUT14 isw2_c.i. Fazzio01 -1.14 0.0719 49ABF1_YPD IES6 Hughes00 -1.14 0.072 265RTG3_RAPA ino80_+_0.1%_MMS_vs._ino80Attikum04 1.14 0.0721 43FKH2_YPD MOT1-42 Dasgupta02 -1.14 0.0721 121NRG1_YPD Dsds3 Keogh05 -1.14 0.0723 64DAL82_SM isw2_sin3 Fazzio01 -1.13 0.0725 50STE12_BUT90 Drxt1 Keogh05 -1.13 0.0725 77MSN2_H2O2HiDrxt2 Keogh05 1.13 0.0726 74PHD1_BUT90 htz1_hmr Meneghini03 -1.13 0.0727 103NDD1_YPD elp3D Durant06 1.13 0.0727 74PHD1_YPD Ddep1 Keogh05 -1.13 0.0728 59ROX1_YPD SIR2 Hughes00 1.13 0.0729 67CBF1_SM ISW1 Hughes00 -1.13 0.0729 278HAP4_YPD EAF5 Krogan04 1.13 0.073 53REB1_YPD H3_1-28 Sabet04 1.13 0.0731 141ROX1_YPD rpd3_c.i. Fazzio01 -1.13 0.0731 67GCR2_SM SSD1-V Kaeberlein04 1.13 0.0731 54CIN5_YPD SWD2 Mnaimneh_04 1.13 0.0732 150GCN4_SM WT_WT Chitikila_02 -1.13 0.0732 185SOK2_BUT14 htz1 Meneghini03 1.13 0.0732 70MSN4_H2O2Hirsc3-2 Angus-Hill_01 -1.13 0.0733 70FKH1_YPD Drxt1 Keogh05 1.13 0.0733 140GCN4_YPD rpd3_c.i. Fazzio01 -1.13 0.0733 73PHO4_YPD ume6 Fazzio01 1.13 0.0734 71GLN3_RAPA SWD2 Mnaimneh_04 1.13 0.0734 68NDD1_YPD hht2_K49141823GMartin04 1.13 0.0734 75YAP1_YPD H4_2-26 Sabet04 1.13 0.0735 69DAL81_RAPA hat1D Durant06 -1.13 0.0735 67GLN3_RAPA ARD1 Hughes00 -1.13 0.0735 67ABF1_YPD hat1_vs.YPH250Rosaleny05 -1.13 0.0736 251MBP1_H2O2Loino80_del Mizuguch04 -1.13 0.0736 58MGA1_YPD set1 Boa03 -1.13 0.0736 59

ABF1_YPD hht2K9131823GMartin04 -1.13 0.0738 235YAP7_H2O2Hi ARD1 Hughes00 1.13 0.0739 139CIN5_H2O2Lo isw2_ume6 Fazzio01 1.13 0.0739 125CIN5_YPD hht2_K27G Martin04 -1.13 0.074 110CBF1_SM htz1 Meneghini03 1.13 0.074 272CBF1_SM DT_Null Chitikila_02 -1.13 0.074 266STE12_BUT90 WT_V161R_K Chitikila_02 -1.13 0.074 67STE12_YPD BUR6 Geisberg_01 1.13 0.0741 52DAL81_RAPA MED2_haploid Hughes00 -1.13 0.0741 94GLN3_RAPA WT_V161R_L Chitikila_02 -1.13 0.0741 65MSN2_H2O2HiVID21 Krogan04 1.13 0.0741 71PUT3_H2O2Lo ino80 Attikum04 1.13 0.0741 64HSF1_H2O2Hi H4_2-26 Sabet04 1.12 0.0742 120STE12_Alpha ume6_del Bernstein_00_affydeletions-1.12 0.0742 107STE12_Alpha _SWC2_(VPS72)Krogan04 1.12 0.0743 110SWI6_YPD HST3 Hughes00 -1.12 0.0744 152FKH2_H2O2Hi gcn5D Durant06 -1.12 0.0745 89MSN2_H2O2HiSWD2 Mnaimneh_04 1.12 0.0745 78HAP1_YPD set1 Boa03 1.12 0.0745 140NRG1_YPD _SWC2_(VPS72)Krogan04 1.12 0.0745 65SWI6_YPD RAD6_haploid Hughes00 -1.12 0.0746 151OAF1_YPD taf1-ts2_spt3 Huisinga04 -1.12 0.0746 56AFT2_H2O2Hi Ddep1 Keogh05 1.12 0.0747 56AFT2_H2O2Lo ino80 Attikum04 1.12 0.0747 68PUT3_H2O2Lo spt3_E240K Huisinga04 -1.12 0.0747 76REB1_YPD isw2_c.i. Fazzio01 1.12 0.0748 142PHD1_YPD MOT1-14 Dasgupta02 1.12 0.0749 67SWI5_YPD sap30_del Bernstein_00_affydeletions1.12 0.0749 86DIG1_Alpha rpd3_H4KQ_v_H4KQSabet04 -1.12 0.0749 56STE12_Alpha H4KQ Sabet04 -1.12 0.0749 109MBP1_H2O2LoWT_V71E Chitikila_02 -1.12 0.075 51PUT3_H2O2Lo spt10 Eriksson05 1.12 0.075 85GCN4_YPD hpa2D Durant06 1.12 0.075 66SUM1_YPD WT_N69S Chitikila_02 1.12 0.0751 48SUT1_YPD swi1_minimal_medium_experimentSudarsanam00 -1.12 0.0751 69RCS1_H2O2Hi hht2_K914182327GMartin04 1.12 0.0751 38SOK2_BUT14 rpd3_del Sabet04 -1.12 0.0751 65MSN4_RAPA UBP8 Hughes00 -1.12 0.0752 53REB1_YPD DT_N69S Chitikila_02 1.12 0.0754 130RIM101_H2O2LoBUR6 Geisberg_01 1.12 0.0754 46DIG1_BUT14 rpd3_del Sabet04 -1.12 0.0754 63HSF1_H2O2LoZDS1 Hughes00 1.12 0.0755 100DAL82_SM htz1_hmr Meneghini03 1.12 0.0756 55AFT2_H2O2Lo spt3_E240K Huisinga04 -1.12 0.0756 88SOK2_BUT14 sir4 Orlandi04 -1.12 0.0756 38SKN7_H2O2LoHIR2 Hughes00 1.12 0.0757 182RCS1_H2O2Hi HDA1 Hughes00 1.12 0.0758 52RPN4_H2O2Lorpd3 Fazzio01 1.12 0.0758 97YAP6_H2O2Hi taf1-ts2_25C Huisinga04 -1.11 0.0759 75REB1_YPD RSC8 Mnaimneh_04 -1.11 0.076 145AFT2_H2O2Hi WT_V161E Chitikila_02 -1.11 0.076 57MBP1_H2O2LoSIN3 Hughes00 1.11 0.076 57MSN4_RAPA WT_N69S Chitikila_02 1.11 0.0761 48

HSF1_H2O2Lorpd3_c.i. Fazzio01 -1.11 0.0761 97ASH1_BUT14 Drco1 Keogh05 1.11 0.0761 45REB1_H2O2Hi BUR6 Geisberg_01 -1.11 0.0762 57DAL82_SM ISW1_ISW2 Hughes00 1.11 0.0765 55ROX1_YPD hpa2D_taf1-ts2Durant06 -1.11 0.0766 39ROX1_YPD WT_N69R Chitikila_02 1.11 0.0766 63RPN4_H2O2LoSAP30 Hughes00 1.11 0.0766 99RPN4_H2O2Lorpd3_H4KQ_v_H4KQSabet04 -1.11 0.0766 98PHO4_YPD DT_V161R_L Chitikila_02 1.11 0.0767 71CIN5_H2O2Lo H4KQ Sabet04 1.11 0.0767 119MBP1_YPD snf2_rich_medium_experimentSudarsanam00 -1.11 0.0767 129ROX1_YPD VID21 Krogan04 1.11 0.0768 59MSN4_RAPA ino80 Attikum04 1.11 0.0768 34PHD1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -1.11 0.0769 48SKN7_H2O2Loisw2_ume6 Fazzio01 -1.11 0.0769 181SKN7_H2O2LoDrco1 Keogh05 1.11 0.0769 171MGA1_YPD gcn5D Durant06 -1.11 0.0769 51SWI5_YPD HIR2 Hughes00 1.11 0.077 100RIM101_H2O2Logcn5_KQL Huisinga04 1.11 0.077 43CIN5_H2O2Lo arp8_+_0.1%_MMS_vs._arp8Attikum04 1.11 0.0771 96CIN5_H2O2Lo sir2 Meneghini03 1.11 0.0771 123SUM1_YPD isw2 Fazzio01 -1.11 0.0772 59SWI6_YPD sas3D Durant06 -1.11 0.0772 129SKN7_H2O2Loswi1_rich_medium_experimentSudarsanam00 -1.11 0.0772 185YAP7_H2O2Lo sir2 Meneghini03 1.11 0.0772 144FKH1_YPD hpa2D_taf1-ts2Durant06 -1.11 0.0772 112NRG1_YPD SPT8 Ingvarsdottir05 -1.11 0.0772 64MSN2_H2O2HiSet1_del Bernstein02 1.11 0.0773 77YAP6_H2O2Lo hpa2D_taf1-ts2Durant06 -1.11 0.0773 35FKH1_YPD swi1_minimal_medium_experimentSudarsanam00 -1.11 0.0773 142CIN5_YPD hat2_vs._hat1Rosaleny05 -1.11 0.0774 143AFT2_H2O2Hi SSN6_haploid Hughes00 1.11 0.0776 60MGA1_YPD HAT2 Hughes00 -1.11 0.0776 62CIN5_YPD taf1-ts2_25C Huisinga04 -1.1 0.0779 130AFT2_H2O2Lo taf1-ts2_gcn5 Huisinga04 1.1 0.0779 94PHD1_BUT90 sir4 Orlandi04 -1.1 0.0779 61HAP1_YPD Set1_del Bernstein02 1.1 0.0779 140SWI5_YPD Dsds3 Keogh05 1.1 0.078 90UME6_YPD SSN6_haploid Hughes00 1.1 0.078 125STE12_YPD Dsds3 Keogh05 -1.1 0.0781 52GCR2_SM sin3_del Bernstein_00_affydeletions1.1 0.0781 54NRG1_YPD ARD1 Hughes00 -1.1 0.0781 72MBP1_H2O2HiZDS1 Hughes00 1.1 0.0782 130MGA1_YPD hpa2D Durant06 1.1 0.0782 45YAP7_H2O2Lo SGF11 Ingvarsdottir05 1.1 0.0783 132MCM1_Alpha VID21 Krogan04 1.1 0.0783 96SWI4_YPD MOT1-42 Dasgupta02 -1.1 0.0784 156DAL82_RAPA ISW2 Hughes00 1.1 0.0784 56HAP4_YPD HIR2 Hughes00 -1.1 0.0784 67YAP7_H2O2Hi sas3D_taf1-ts2Durant06 1.1 0.0785 125SUT1_YPD arp8 Attikum04 1.1 0.0786 48GCR2_SM HTZ1 Krogan04 1.1 0.0786 50GCN4_YPD DT_V71R Chitikila_02 1.1 0.0786 71

DAL82_RAPA H3KQ Sabet04 -1.1 0.0787 53AFT2_H2O2Hi RSC8 Mnaimneh_04 1.1 0.0787 61UME6_H2O2Hielp3D_taf1-ts2Durant06 1.1 0.0787 79PHO4_YPD WT_TAF1_SPT3Huisinga04 1.1 0.0788 68SUM1_YPD sin3_del Bernstein_00_affydeletions-1.1 0.0788 43DAL82_SM taf1-ts2_GCN5Huisinga04 1.1 0.0788 51RLM1_YPD MED2_haploid Hughes00 -1.1 0.0789 55SKN7_YPD gcn5D Durant06 1.1 0.0789 58UME6_YPD elp3D Durant06 1.1 0.0789 95MBP1_YPD ume6 Fazzio01 -1.1 0.0789 123REB1_YPD WT_V71E Chitikila_02 1.1 0.079 124SWI6_YPD Dsds3 Keogh05 1.1 0.079 148ABF1_YPD RSC8 Mnaimneh_04 -1.1 0.0791 267CBF1_SM WT_V161E Chitikila_02 -1.1 0.0791 257MGA1_YPD gcn5 Huisinga04 -1.1 0.0791 56SUM1_YPD hat2_vs._YPH250Rosaleny05 1.1 0.0792 51RTG3_RAPA ARD1 Hughes00 1.1 0.0793 50YAP7_H2O2Hi elp3D_taf1-ts2Durant06 1.1 0.0793 115HAP1_YPD ino80_del Mizuguch04 1.1 0.0793 141STE12_YPD WT_TAF1_GCN5Huisinga04 1.09 0.0796 50MSN4_RAPA SPT3 Ingvarsdottir05 -1.09 0.0798 45GCN4_YPD MED2_haploid Hughes00 -1.09 0.0798 74PHO4_YPD DT_N69R Chitikila_02 1.09 0.0799 70GCN4_YPD WT_V161E Chitikila_02 -1.09 0.0799 74SWI5_YPD _SWC2_(VPS72)Krogan04 1.09 0.0801 96GCN4_RAPA Ddep1 Keogh05 1.09 0.0801 148REB1_H2O2Hi SSN6_haploid Hughes00 -1.09 0.0801 58PHD1_BUT90 gcn5 Huisinga04 1.09 0.0801 99ACE2_YPD H4_2-26 Sabet04 1.09 0.0801 77SUT1_YPD ume6_del Bernstein_00_affydeletions1.09 0.0802 63CIN5_YPD ISW1 Hughes00 -1.09 0.0802 149RLM1_YPD taf1-ts2_25C Huisinga04 1.09 0.0803 47YAP6_YPD swi1_rich_medium_experimentSudarsanam00 -1.09 0.0803 91SKN7_YPD hos2_del Bernstein_00_affydeletions1.09 0.0804 54GLN3_RAPA hht2_K49141823GMartin04 1.09 0.0804 51RCS1_H2O2LoSPT8 Ingvarsdottir05 1.09 0.0804 233STP1_SM WT_V71E Chitikila_02 -1.09 0.0805 55YAP6_H2O2Hi SPT8 Ingvarsdottir05 -1.09 0.0805 68MGA1_YPD WT_V161R_K Chitikila_02 1.09 0.0805 54SWI5_YPD sin3_del Bernstein_00_affydeletions-1.09 0.0806 89HSF1_H2O2Hi IES6 Hughes00 1.09 0.0807 123RCS1_H2O2Lohat2_vs._YPH250Rosaleny05 1.09 0.0807 249YAP6_H2O2Lo hht2_K49141823GMartin04 -1.09 0.0807 36SUT1_YPD MED2_haploid Hughes00 -1.09 0.0808 69CIN5_H2O2Hi swr1_del Mizuguch04 -1.09 0.0808 80MSN2_H2O2Hihos2_del Bernstein_00_affydeletions1.09 0.0808 71NRG1_H2O2HiDT_Null Chitikila_02 1.09 0.0808 116RCS1_H2O2Hi SPT8 Ingvarsdottir05 1.09 0.0808 45SKN7_H2O2Hi htz1_sir2 Meneghini03 1.09 0.0808 98RCS1_H2O2Loino80_+_0.1%_MMS_vs._ino80Attikum04 -1.09 0.0808 209PHD1_BUT90 DT_V161R_K Chitikila_02 1.09 0.0808 102RCS1_H2O2Lotaf1-ts2 Durant06 1.09 0.0809 251DIG1_Alpha SWR1 Krogan04 1.09 0.0809 58

SOK2_BUT14 hos2_del Bernstein_00_affydeletions-1.09 0.0809 60YAP6_H2O2Lo UBP8 Hughes00 1.09 0.081 58DAL81_RAPA hat1_vs.YPH250Rosaleny05 1.09 0.0811 91DAL82_SM Hda1_del Bernstein02 1.09 0.0812 54RCS1_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 1.09 0.0812 52PHD1_BUT90 H4KQ Sabet04 1.09 0.0812 96FKH2_YPD WT_V71R Chitikila_02 -1.08 0.0813 110PHO4_YPD YNG2 Krogan04 -1.08 0.0814 70SKN7_H2O2HiDT_N69S Chitikila_02 -1.08 0.0814 88GLN3_RAPA sap30_del Bernstein_00_affydeletions-1.08 0.0815 63CIN5_H2O2Hi H4_2-26 Sabet04 1.08 0.0815 74OAF1_YPD WT_V161R_L Chitikila_02 -1.08 0.0815 54GCN4_SM hht2_K914182327GMartin04 1.08 0.0816 161SWI6_YPD TAF2 Mnaimneh_04 1.08 0.0817 153YAP7_H2O2Hi sir2 Meneghini03 1.08 0.0817 135DIG1_BUT14 spt3_E240K Huisinga04 -1.08 0.0818 56MBP1_YPD swr1_del Mizuguch04 1.08 0.0818 128GCN4_SM SAP30 Hughes00 1.08 0.0819 188FKH2_H2O2Hi hpa2D Durant06 -1.08 0.0819 79STE12_Alpha Dpho23 Keogh05 -1.08 0.0819 113CIN5_H2O2Hi htz1 Meneghini03 1.08 0.0821 79MSN4_H2O2Hiswi1_rich_medium_experimentSudarsanam00 1.08 0.0821 70RPN4_H2O2LoDT_N69S Chitikila_02 -1.08 0.0821 95SWI6_YPD elp3D Durant06 1.08 0.0822 131GCN4_RAPA DT_N69R Chitikila_02 1.08 0.0822 151SWI5_YPD htz1_hmr Meneghini03 1.08 0.0823 99YAP6_YPD MOT1-14 Dasgupta02 1.08 0.0823 91FKH2_H2O2Hi hat2_vs._hat1Rosaleny05 -1.08 0.0824 101GCN4_SM DT_V161R_K Chitikila_02 -1.08 0.0825 181NRG1_H2O2Hisin3_del Bernstein_00_affydeletions1.08 0.0825 114AFT2_H2O2Lo WT_F182V Chitikila_02 1.08 0.0826 81OAF1_YPD WT_V161E Chitikila_02 -1.08 0.0826 52MCM1_Alpha Dpho23 Keogh05 1.08 0.0827 106SKN7_YPD taf1-ts2_25C Huisinga04 1.08 0.0829 60GCN4_RAPA hos2_del Bernstein_00_affydeletions-1.08 0.0829 155GCN4_SM delta_ssd1 Kaeberlein04 1.08 0.083 188FKH2_YPD DM_vs._YPH250Rosaleny05 1.08 0.083 107PHO4_YPD rpd3_H3dN_v_H3dNSabet04 -1.08 0.0831 70STE12_YPD ZDS1 Hughes00 1.07 0.0832 53GLN3_RAPA HTZ1 Krogan04 1.07 0.0833 63XBP1_H2O2Lo hos2_del Bernstein_00_affydeletions-1.07 0.0833 54ACE2_YPD SAP30 Hughes00 1.07 0.0833 80SWI5_YPD DT_Null Chitikila_02 1.07 0.0834 94CIN5_YPD MOT1-42 Dasgupta02 1.07 0.0834 150RIM101_H2O2LoDrxt2 Keogh05 -1.07 0.0834 52ASH1_BUT14 SIR2 Hughes00 -1.07 0.0834 50RCS1_H2O2Hi MED2_haploid Hughes00 1.07 0.0835 52UME6_H2O2HiDT_N69R Chitikila_02 1.07 0.0835 89RCS1_H2O2Hi H3_1-28 Sabet04 1.07 0.0836 50DIG1_BUT14 PCH1 Hughes00 -1.07 0.0836 62STE12_BUT90 TAF2 Mnaimneh_04 1.07 0.0836 77NRG1_YPD SIR2 Hughes00 1.07 0.0836 72MSN4_H2O2HiDT_V71E Chitikila_02 -1.07 0.0837 68

AFT2_H2O2Lo SIN3 Hughes00 1.07 0.0837 96CIN5_YPD H3KQ Sabet04 1.07 0.0838 144MSN4_RAPA sir4 Orlandi04 1.07 0.0839 26MSN4_RAPA Dsds3 Keogh05 -1.07 0.084 50GCN4_YPD isw2_rpd3_vs._rpd3Fazzio01 -1.07 0.084 74REB1_H2O2Hi WT_TAF1_SPT3Huisinga04 -1.07 0.0841 58XBP1_H2O2Lo WT_N69S Chitikila_02 1.07 0.0842 62PHD1_YPD H3KQ Sabet04 1.07 0.0843 62STE12_Alpha WT_N69S Chitikila_02 1.07 0.0843 100MGA1_YPD WT_V161E Chitikila_02 1.07 0.0843 55CIN5_H2O2Hi UBP8 Hughes00 1.07 0.0844 78STP1_SM Hda1_del Bernstein02 -1.07 0.0845 67SKN7_H2O2HiMED2_haploid Hughes00 -1.07 0.0845 96YAP6_H2O2Hi esa1-414 Durant06 -1.07 0.0845 67PHO4_YPD spt10 Eriksson05 1.07 0.0846 71HSF1_H2O2Lohht2_K4G Martin04 1.07 0.0846 82UME6_YPD SIR4 Hughes00 -1.07 0.0847 130RIM101_H2O2Lohtz1 Meneghini03 -1.07 0.0847 53ROX1_YPD rpd3 Fazzio01 -1.07 0.0848 67MCM1_Alpha taf1-ts2 Durant06 1.07 0.0848 103MBP1_H2O2Loino80_+_0.1%_MMS_vs._ino80Attikum04 1.07 0.0849 47SKN7_H2O2LoSPT3 Ingvarsdottir05 -1.07 0.085 154CIN5_H2O2Lo ubp10 Orlandi04 1.07 0.0851 66MCM1_Alpha sas3D_taf1-ts2Durant06 1.07 0.0851 91HAP1_YPD DT_V71E Chitikila_02 -1.06 0.0852 137YAP7_H2O2Lo taf1-ts2 Durant06 1.06 0.0853 151STE12_Alpha MOT1-42 Dasgupta02 1.06 0.0853 114FKH1_YPD hda1_del Bernstein_00_affydeletions-1.06 0.0853 135MCM1_Alpha SPT3 Ingvarsdottir05 1.06 0.0854 94STE12_BUT14 DT_V161E Chitikila_02 -1.06 0.0854 114MBP1_YPD htz1_sir2 Meneghini03 1.06 0.0854 130REB1_YPD SSN6_haploid Hughes00 -1.06 0.0856 140DAL82_SM ubp10 Orlandi04 -1.06 0.0856 34FKH1_YPD htz1_sir2 Meneghini03 1.06 0.0856 139MCM1_YPD EAF5 Krogan04 1.06 0.0856 73SKN7_YPD rpd3_c.i. Fazzio01 -1.06 0.0857 63SWI4_YPD SWR1 Krogan04 1.06 0.0857 148DIG1_Alpha isw2_c.i. Fazzio01 1.06 0.0857 59MSN4_RAPA DT_V161R_L Chitikila_02 1.06 0.0858 48SOK2_BUT14 SPT8 Ingvarsdottir05 -1.06 0.0858 66AFT2_H2O2Hi H3KQ Sabet04 1.06 0.0859 56ASH1_BUT14 rpd3_H3dN_v_H3dNSabet04 -1.06 0.0859 47ROX1_YPD DT_N69S Chitikila_02 -1.06 0.086 62GCR2_SM Drxt1 Keogh05 1.06 0.086 53GLN3_RAPA DT_Null Chitikila_02 -1.06 0.086 63MBP1_H2O2Hihht2_K914182327GMartin04 1.06 0.086 108STE12_YPD sir4 Orlandi04 -1.06 0.0861 39RCS1_H2O2Loelp3D_taf1-ts2Durant06 1.06 0.0862 205YAP6_YPD DT_V161R_K Chitikila_02 1.06 0.0863 88CBF1_SM Dsap30 Keogh05 1.06 0.0863 249GCN4_SM isw2 Fazzio01 1.06 0.0863 183SOK2_BUT14 UBP8 Hughes00 1.06 0.0863 72GCN4_SM SGF11 Ingvarsdottir05 -1.06 0.0864 163

RTG3_RAPA IES6 Hughes00 -1.06 0.0864 51MBP1_H2O2HiDsap30 Keogh05 1.06 0.0864 127DAL82_SM EAF7 Krogan04 1.06 0.0866 44SUM1_YPD isw2_ume6 Fazzio01 1.06 0.0869 59RCS1_H2O2LoDsds3 Keogh05 1.06 0.0869 231STE12_YPD hmr Meneghini03 -1.06 0.087 52ACE2_YPD delta_ssd1 Kaeberlein04 1.06 0.087 80CIN5_H2O2Hi Rpd3_del Bernstein02 -1.05 0.0872 80ASH1_BUT14 hat1_vs.YPH250Rosaleny05 1.05 0.0873 44RLM1_YPD DT_V71R Chitikila_02 -1.05 0.0874 51SKN7_YPD _SWC2_(VPS72)Krogan04 1.05 0.0874 61SWI5_YPD ino80_del Mizuguch04 1.05 0.0874 102FKH2_H2O2Hi taf1-ts2 Durant06 1.05 0.0874 103NRG1_YPD SIN3 Hughes00 -1.05 0.0874 70GCR2_SM Rpd3_del Bernstein02 1.05 0.0875 54YAP6_H2O2Lo YNG2 Krogan04 -1.05 0.0875 56AFT2_H2O2Hi SIN3 Hughes00 1.05 0.0876 60HSF1_H2O2LoMOT1-42 Dasgupta02 1.05 0.0876 100ASH1_BUT14 WT_F182V Chitikila_02 1.05 0.0876 42XBP1_H2O2Lo taf1-ts2_SPT3 Huisinga04 -1.05 0.0877 63HSF1_H2O2LoMOT1-14 Dasgupta02 1.05 0.0878 97RIM101_H2O2LoDrco1 Keogh05 1.05 0.0878 50STE12_Alpha UBP8 Ingvarsdottir05 1.05 0.0878 104PHD1_YPD MED2_haploid Hughes00 1.05 0.0879 66YAP6_YPD rsc3-2 Angus-Hill_01 1.05 0.088 91UME6_YPD rpd3_H4KQ_v_H4KQSabet04 1.05 0.0881 129DAL82_SM WT_V161R_K Chitikila_02 -1.05 0.0881 52MSN4_H2O2Hiisw2_sin3_vs._sin3Fazzio01 -1.05 0.0881 68ROX1_YPD ino80 Attikum04 1.05 0.0882 47GCN4_SM hht2_K4G Martin04 1.05 0.0882 163HSF1_H2O2Logcn5 Huisinga04 -1.05 0.0883 97DAL82_RAPA swi1_rich_medium_experimentSudarsanam00 1.05 0.0884 56FKH2_H2O2Hi SSN6_haploid Hughes00 1.05 0.0884 102STE12_Alpha SPT8 Ingvarsdottir05 -1.05 0.0884 103STE12_Alpha SWC6_(VPS71)Krogan04 1.05 0.0884 102STE12_BUT14 taf1-ts2_gcn5 Huisinga04 1.05 0.0884 121PUT3_H2O2Lo hht2_K4G Martin04 -1.05 0.0885 66STE12_BUT90 ubp10sir4 Orlandi04 -1.05 0.0885 58PHD1_BUT90 Dsds3 Keogh05 -1.05 0.0886 96NRG1_YPD hat1D Durant06 -1.05 0.0886 41AFT2_H2O2Lo hat1D Durant06 -1.05 0.0887 75FKH2_YPD hht2K9131823GMartin04 1.05 0.0887 100CIN5_H2O2Lo ARD1 Hughes00 -1.05 0.0888 126XBP1_H2O2Lo Dpho23 Keogh05 -1.05 0.0888 66PHD1_BUT90 WT_V71E Chitikila_02 -1.05 0.0888 88GCN4_SM H4_2-26 Sabet04 1.05 0.0889 183SKN7_YPD Dpho23 Keogh05 1.05 0.089 65STE12_BUT90 RPD3_haploid Hughes00 1.05 0.089 77DAL81_RAPA ISW2 Hughes00 -1.05 0.0891 94FKH2_YPD Dsds3 Keogh05 1.05 0.0891 112MSN4_H2O2Hisin3 Fazzio01 1.04 0.0892 68DIG1_Alpha isw2_rpd3 Fazzio01 -1.04 0.0892 59MBP1_H2O2Hihos3_del Bernstein_00_affydeletions-1.04 0.0893 124

NRG1_H2O2Hiino80_+_0.1%_MMS_vs._ino80Attikum04 -1.04 0.0894 87NRG1_YPD IOC4 Hughes00 1.04 0.0895 72YAP6_H2O2Lo htz1_del Mizuguch04 -1.04 0.0896 58STP1_SM rsc3-2 Angus-Hill_01 1.04 0.0897 65DAL81_RAPA H3KQ Sabet04 1.04 0.0897 94ACE2_YPD VID21 Krogan04 1.04 0.0897 71MSN4_H2O2Hihht2_K27G Martin04 1.04 0.0898 61HAP1_YPD _SWC2_(VPS72)Krogan04 1.04 0.0898 129NDD1_YPD RSC8 Mnaimneh_04 1.04 0.0898 85SWI6_YPD gcn5D_taf1-ts2Durant06 1.04 0.0899 144OAF1_YPD DT_N69S Chitikila_02 -1.04 0.0899 53SKN7_YPD DT_N69S Chitikila_02 1.04 0.09 62SWI4_YPD SPT3 Ingvarsdottir05 1.04 0.09 138CBF1_SM Hda1_del Bernstein02 1.04 0.09 275UME6_H2O2HiISW1_ISW2 Hughes00 1.04 0.09 101SUT1_YPD hht2_K27G Martin04 1.04 0.0901 48SWI6_YPD SWR1 Krogan04 1.04 0.0902 145NRG1_YPD WT_V161E Chitikila_02 -1.04 0.0902 67DAL82_SM gcn5_KQL Huisinga04 -1.04 0.0903 48AFT2_H2O2Hi WT_F182V Chitikila_02 1.04 0.0903 49MGA1_YPD hht2_K4G Martin04 -1.04 0.0903 48PHO4_YPD isw2_sin3 Fazzio01 1.04 0.0905 71RLM1_YPD hat2_vs._YPH250Rosaleny05 -1.04 0.0905 53SUT1_YPD snf2_minimal_medium_experimentSudarsanam00 -1.04 0.0906 69MCM1_YPD ume6 Fazzio01 1.04 0.0906 73DAL82_SM SSD1-V Kaeberlein04 1.04 0.0907 55RCS1_H2O2Hi htz1 Meneghini03 -1.04 0.0907 50HSF1_H2O2Hi DT_V161E Chitikila_02 -1.04 0.0908 121RCS1_H2O2Hi hht2_K27G Martin04 1.04 0.0908 38UME6_YPD snf2_minimal_medium_experimentSudarsanam00 1.04 0.0909 131UME6_YPD VID21 Krogan04 1.04 0.0909 114MSN4_H2O2HiARD1 Hughes00 1.04 0.0909 69GCR2_SM ino80_+_0.1%_MMS_vs._ino80Attikum04 -1.04 0.0911 44STE12_BUT90 Drxt2 Keogh05 1.04 0.0912 75HAP4_YPD SSD1-V Kaeberlein04 1.04 0.0912 67ROX1_YPD htz1_hmr Meneghini03 -1.03 0.0913 65SKN7_YPD ubp10 Orlandi04 1.03 0.0913 39MSN4_H2O2Hiino80_del Mizuguch04 1.03 0.0913 69ASH1_BUT14 WT_Null_K Chitikila_02 -1.03 0.0913 49AFT2_H2O2Hi SAP30 Hughes00 1.03 0.0915 61XBP1_H2O2Lo sas3D Durant06 -1.03 0.0915 47YAP6_H2O2Lo Dume1 Keogh05 -1.03 0.0915 53NRG1_H2O2HiDT_N69S Chitikila_02 -1.03 0.0916 107FKH2_YPD isw2_rpd3_vs._rpd3Fazzio01 1.03 0.0916 119PHD1_YPD SPT3 Ingvarsdottir05 -1.03 0.0918 60REB1_YPD MOT1-14 Dasgupta02 -1.03 0.0918 137YAP6_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 1.03 0.0918 79SUM1_YPD isw2_c.i. Fazzio01 -1.03 0.0919 59CBF1_SM BUR6 Geisberg_01 1.03 0.0919 267DIG1_BUT14 ino80 Attikum04 -1.03 0.0919 53PHD1_BUT90 SPT8 Ingvarsdottir05 -1.03 0.0919 100SKN7_H2O2HiDT_WT Chitikila_02 -1.03 0.092 91RLM1_YPD taf1-ts2_GCN5Huisinga04 1.03 0.0921 52

SUT1_YPD elp3D Durant06 -1.03 0.0921 53DIG1_Alpha WT Durant06 -1.03 0.0921 55RPN4_H2O2LoRpd3_del Bernstein02 1.03 0.0922 99STP1_SM H4_2-26 Sabet04 -1.03 0.0923 67ASH1_BUT14 ubp10sir4 Orlandi04 -1.03 0.0923 31STE12_YPD SWC6_(VPS71)Krogan04 1.03 0.0924 47FKH2_H2O2Hi ZDS1 Hughes00 -1.03 0.0924 106HSF1_H2O2Lohht2_K49141823GMartin04 1.03 0.0924 82DIG1_BUT14 ubp10 Orlandi04 -1.03 0.0924 43DAL81_RAPA PCH1 Hughes00 1.03 0.0926 93MSN4_RAPA esa1-414_taf1-ts2Durant06 1.03 0.0926 46REB1_H2O2Hi arp8 Attikum04 -1.03 0.0928 46DIG1_Alpha hht2K9131823GMartin04 1.03 0.0928 41AFT2_H2O2Hi HST3 Hughes00 1.03 0.0929 60RPN4_H2O2LoSPT3 Ingvarsdottir05 1.03 0.0929 87HAP1_YPD hmr Meneghini03 -1.03 0.0929 133MBP1_YPD SSD1-V Kaeberlein04 1.03 0.093 129SWI4_YPD snf2_rich_medium_experimentSudarsanam00 -1.03 0.0931 155YAP6_YPD ubp10 Orlandi04 1.03 0.0931 56GCN4_SM YNG2 Krogan04 1.03 0.0931 179XBP1_H2O2Lo hht2_K49141823GMartin04 1.03 0.0931 44STE12_YPD SIR2 Hughes00 -1.03 0.0933 53YAP7_H2O2Hi WT_WT Chitikila_02 1.03 0.0933 135TYE7_YPD WT_N69S Chitikila_02 1.02 0.0934 49GCR2_SM HIR2 Hughes00 1.02 0.0934 53NDD1_YPD hht2_K4G Martin04 1.02 0.0935 75ABF1_YPD taf1-ts2_gcn5_KQLHuisinga04 1.02 0.0936 249YAP1_YPD htz1_del Mizuguch04 1.02 0.0936 71DAL81_RAPA htz1_hmr Meneghini03 1.02 0.0937 91FKH2_YPD esa1-414_taf1-ts2Durant06 1.02 0.0937 111GLN3_RAPA _SWC2_(VPS72)Krogan04 1.02 0.0938 63CIN5_H2O2Hi YAF9 Krogan04 -1.02 0.0938 75CIN5_H2O2Lo Drco1 Keogh05 1.02 0.0938 118YAP7_H2O2Lo DT_V71E Chitikila_02 -1.02 0.0938 146SWI4_YPD spt10 Eriksson05 -1.02 0.094 156MSN2_H2O2Hisin3_del Bernstein_00_affydeletions1.02 0.0941 69OAF1_YPD SPT8 Ingvarsdottir05 -1.02 0.0941 53ABF1_YPD gcn5 Huisinga04 1.02 0.0942 253CIN5_H2O2Lo WT_N69S Chitikila_02 -1.02 0.0942 116NRG1_H2O2Hihtz1_del Mizuguch04 -1.02 0.0944 126ACE2_YPD arp8 Attikum04 1.02 0.0944 60OAF1_YPD BUR6 Geisberg_01 1.02 0.0945 54SOK2_BUT14 Drco1 Keogh05 1.02 0.0946 69YAP7_H2O2Lo ubp10 Orlandi04 -1.02 0.0947 94MBP1_YPD HST3 Hughes00 -1.02 0.0947 130DAL82_SM hmr Meneghini03 -1.02 0.0949 55YAP1_YPD gcn5D_taf1-ts2Durant06 1.02 0.095 66SKN7_H2O2LoWT_TAF1_SPT3Huisinga04 1.02 0.0951 174STE12_BUT90 sir2 Meneghini03 -1.02 0.0951 77GCN4_RAPA gcn5D_taf1-ts2Durant06 1.02 0.0952 152ACE2_YPD hat1_vs.YPH250Rosaleny05 1.02 0.0952 75DAL82_SM WT_V161E Chitikila_02 -1.02 0.0953 51CIN5_H2O2Lo snf2_rich_medium_experimentSudarsanam00 1.02 0.0953 126

REB1_YPD SIR4 Hughes00 -1.02 0.0954 141SKN7_H2O2LoSWD2 Mnaimneh_04 1.02 0.0954 186MGA1_YPD ume6 Fazzio01 -1.02 0.0954 60DAL82_RAPA WT_V71E Chitikila_02 -1.01 0.0955 46YAP7_H2O2Hi spt3_E240K Huisinga04 1.01 0.0955 125AFT2_H2O2Hi WT_Null_K Chitikila_02 -1.01 0.0956 58CIN5_H2O2Hi gcn5D Durant06 -1.01 0.0957 63ROX1_YPD H4_2-26 Sabet04 1.01 0.0958 58STE12_YPD DT_N69R Chitikila_02 -1.01 0.0958 47SWI4_YPD RSC8 Mnaimneh_04 1.01 0.0958 156DAL82_SM HIR2 Hughes00 1.01 0.0958 52MSN2_H2O2Hiswi1_minimal_medium_experimentSudarsanam00 1.01 0.0959 78REB1_YPD snf2_minimal_medium_experimentSudarsanam00 -1.01 0.096 143ABF1_YPD DT_V71R Chitikila_02 1.01 0.0961 255ASH1_BUT14 spt3_E240K Huisinga04 -1.01 0.0961 42MCM1_YPD WT_V161R_K Chitikila_02 1.01 0.0961 63SWI4_YPD swi1_rich_medium_experimentSudarsanam00 -1.01 0.0962 156MSN4_H2O2HiSIR2 Hughes00 1.01 0.0962 68ASH1_BUT14 Deaf3 Keogh05 1.01 0.0962 42NDD1_YPD HAT2 Hughes00 1.01 0.0963 84AFT2_H2O2Lo snf2_rich_medium_experimentSudarsanam00 1.01 0.0964 96TYE7_YPD isw2_c.i. Fazzio01 -1.01 0.0965 54YAP6_H2O2Lo Drxt2 Keogh05 -1.01 0.0966 55OAF1_YPD WT_V161R_K Chitikila_02 -1.01 0.0966 50OAF1_YPD gcn5_KQL Huisinga04 1.01 0.0966 54DAL82_SM taf1-ts2_SPT3 Huisinga04 1.01 0.0967 52PUT3_H2O2Lo snf2_rich_medium_experimentSudarsanam00 1.01 0.0968 87PHD1_BUT90 SIR1 Hughes00 1.01 0.0968 105SOK2_BUT14 WT_Null_L Chitikila_02 1.01 0.0969 69TYE7_YPD PCH1 Hughes00 1.01 0.097 54YAP6_H2O2Hi SIN3 Hughes00 -1.01 0.0971 77RPN4_H2O2Lohht2K9131823GMartin04 -1.01 0.0971 90ROX1_YPD hht2_K4914182327GMartin04 1.01 0.0973 42SKN7_YPD HAT2 Hughes00 1.01 0.0973 63AFT2_H2O2Hi isw2_ume6 Fazzio01 1.01 0.0975 58NRG1_H2O2HiH4KQ Sabet04 1.01 0.0975 119PUT3_H2O2Lo hpa2D_taf1-ts2Durant06 1.01 0.0975 63PHD1_BUT90 WT_F182V Chitikila_02 1.01 0.0975 91ABF1_YPD hht2_K914182327GMartin04 1.01 0.0976 234SWI4_YPD DT_V161R_K Chitikila_02 -1.01 0.0976 151YAP7_H2O2Lo spt3 Huisinga04 -1.01 0.0976 146STE12_BUT90 IES6 Hughes00 -1.01 0.0976 78HAP1_YPD SAP30 Hughes00 -1.01 0.0976 139MBP1_H2O2Hi rpd3_del Sabet04 -1.01 0.0977 129YAP7_H2O2Hi DT_WT Chitikila_02 1.01 0.0977 138CIN5_H2O2Lo gcn5D_taf1-ts2Durant06 -1.01 0.0977 112SOK2_BUT14 Drxt2 Keogh05 -1.01 0.0977 71AFT2_H2O2Lo Deaf3 Keogh05 1 0.0978 88STE12_Alpha Drco1 Keogh05 -1 0.0978 113HAP1_YPD SWC6_(VPS71)Krogan04 1 0.0978 129REB1_H2O2Hi YAF9 Krogan04 -1 0.098 56REB1_YPD DT_V161E Chitikila_02 1 0.0981 131DAL82_SM MOT1-14 Dasgupta02 1 0.0982 55

STE12_BUT14 ume6_del Bernstein_00_affydeletions-1 0.0982 121CIN5_YPD SPT8 Ingvarsdottir05 -1 0.0983 136GCN4_SM Dsds3 Keogh05 1 0.0983 161SWI5_YPD WT_V161E Chitikila_02 -1 0.0984 90REB1_H2O2Hi set1 Boa03 1 0.0984 58UME6_H2O2HiH3KQ Sabet04 1 0.0984 99SUT1_YPD taf1-ts2_GCN5Huisinga04 1 0.0985 66DIG1_BUT14 taf1-ts2_25C Huisinga04 1 0.0985 61MCM1_YPD hos3_del Bernstein_00_affydeletions-1 0.0985 69HAP1_YPD htz1_hmr Meneghini03 1 0.0986 132SWI4_YPD isw2 Fazzio01 1 0.0987 152SUT1_YPD hpa2D_taf1-ts2Durant06 1 0.0988 48GCR2_SM ino80_del Mizuguch04 -1 0.0989 54GCN4_RAPA hht2_K914182327GMartin04 1 0.0989 131MBP1_H2O2Loisw2_sin3_vs._sin3Fazzio01 1 0.0989 54RIM101_H2O2LoRSC8 Mnaimneh_04 1 0.0989 54MBP1_YPD ARP4 Mnaimneh_04 1 0.0989 130ABF1_YPD snf2_minimal_medium_experimentSudarsanam00 -1 0.0991 266RLM1_YPD htz1_sir2 Meneghini03 1 0.0991 51SWI4_YPD H3KQ Sabet04 -1 0.0991 151PUT3_H2O2Lo Drco1 Keogh05 1 0.0991 83MSN4_RAPA BUR6 Geisberg_01 -1 0.0992 49RTG3_RAPA swi1_rich_medium_experimentSudarsanam00 1 0.0992 52RCS1_H2O2Hi spt3_E240K Huisinga04 -1 0.0994 45CIN5_H2O2Lo hht2K9131823GMartin04 1 0.0994 86NRG1_YPD isw2_sin3_vs._sin3Fazzio01 1 0.0994 70YAP6_YPD SPT3 Ingvarsdottir05 -1 0.0995 79CIN5_YPD isw2 Fazzio01 -1 0.0995 148MSN2_H2O2Hiset1 Boa03 1 0.0995 78MSN4_H2O2Hitaf1-ts2_25C Huisinga04 1 0.0995 60PHD1_YPD spt10 Eriksson05 1 0.0997 62PHO4_YPD spt3_E240K Huisinga04 1 0.0997 64XBP1_H2O2Lo SGF11 Ingvarsdottir05 1 0.0997 58MCM1_YPD WT_WT Chitikila_02 -1 0.0999 71HAP1_YPD taf1-ts2_25C Huisinga04 0.99 0.1 131MBP1_H2O2HiYNG2 Mnaimneh_04 0.99 0.1001 133RPN4_H2O2LoH4KQ Sabet04 0.99 0.1002 98HAP1_YPD ubp10sir4 Orlandi04 0.99 0.1002 107XBP1_H2O2Lo taf1-ts2_gcn5_KQLHuisinga04 0.99 0.1003 56REB1_H2O2Hi WT_V71E Chitikila_02 0.99 0.1004 48OAF1_YPD EAF5 Krogan04 -0.99 0.1004 52PHD1_BUT90 Ddep1 Keogh05 -0.99 0.1005 100MSN4_H2O2Hihda1_del Bernstein_00_affydeletions0.99 0.1006 64ACE2_YPD taf1-ts2_25C Huisinga04 0.99 0.1006 71PHD1_YPD H4KQ Sabet04 0.99 0.1008 62REB1_H2O2Hi rpd3_c.i. Fazzio01 0.99 0.1008 57RPN4_H2O2Loisw2_sin3 Fazzio01 -0.99 0.1008 97ASH1_BUT14 SSD1-V Kaeberlein04 0.99 0.1008 49STE12_BUT90 SWD2 Mnaimneh_04 0.99 0.1009 78ROX1_YPD elp3D_taf1-ts2Durant06 -0.99 0.1011 48HSF1_H2O2Lorpd3_del Sabet04 -0.99 0.1011 98PHO4_YPD Dume1 Keogh05 0.99 0.1013 68STE12_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.99 0.1013 42

CBF1_SM DT_V71E Chitikila_02 0.99 0.1013 264UME6_H2O2HiZDS1 Hughes00 0.99 0.1015 98MBP1_H2O2Hi spt3_E240K Huisinga04 -0.99 0.1016 114UME6_H2O2Hiubp10 Orlandi04 0.99 0.1016 53RIM101_H2O2Losas3D Durant06 -0.99 0.1016 43MBP1_YPD rsc30_null Angus-Hill_01 0.99 0.1016 129CIN5_H2O2Hi YNG2 Mnaimneh_04 0.99 0.1017 80MGA1_YPD WT_TAF1_GCN5Huisinga04 -0.99 0.1018 59NRG1_H2O2Hiswr1 Meneghini03 -0.99 0.1019 95SWI5_YPD SSD1-V Kaeberlein04 0.99 0.1021 98OAF1_YPD hos2_del Bernstein_00_affydeletions-0.99 0.1021 52YAP7_H2O2Hi Hda1_del Bernstein02 0.98 0.1024 141MBP1_H2O2Loarp8_+_0.1%_MMS_vs._arp8Attikum04 0.98 0.1024 47FKH1_YPD Dsap30 Keogh05 0.98 0.1024 135NRG1_YPD PCH1 Hughes00 -0.98 0.1024 72CIN5_YPD ISW1_ISW2 Hughes00 0.98 0.1025 150FKH2_H2O2Hi snf2_rich_medium_experimentSudarsanam00 -0.98 0.1025 106RCS1_H2O2Hi set1 Boa03 -0.98 0.1025 50FKH1_YPD hos2_del Bernstein_00_affydeletions0.98 0.1025 136OAF1_YPD SAP30 Hughes00 0.98 0.1025 59FKH2_YPD MED2_haploid Hughes00 -0.98 0.1026 120FKH1_YPD rpd3_H3dN_v_H3dNSabet04 -0.98 0.1027 138FKH2_H2O2Hi ARP4 Mnaimneh_04 0.98 0.1028 105GCN4_YPD TUP1_haploid Hughes00 0.98 0.1028 75HAP1_YPD Drxt2 Keogh05 -0.98 0.1028 132AFT2_H2O2Hi taf1-ts2_gcn5 Huisinga04 0.98 0.103 59SOK2_BUT14 hat1_vs.YPH250Rosaleny05 0.98 0.103 65CIN5_H2O2Hi HTZ1 Krogan04 -0.98 0.1033 73CIN5_H2O2Hi gcn5 Huisinga04 0.98 0.1033 75SWI4_YPD Rpd3_del Bernstein02 0.98 0.1034 154STP1_SM EAF5 Krogan04 0.98 0.1034 62MBP1_H2O2Lohtz1_hmr Meneghini03 0.98 0.1034 57ACE2_YPD rpd3_H3dN_v_H3dNSabet04 0.98 0.1034 77STE12_YPD SSD1-V Kaeberlein04 0.98 0.1036 51AFT2_H2O2Lo MOT1-14 Dasgupta02 0.98 0.1036 98MBP1_YPD HTZ1 Krogan04 0.98 0.1036 122GCN4_SM hht2K9131823GMartin04 0.98 0.1037 166MBP1_H2O2Hihht2_K4G Martin04 0.98 0.1037 112TYE7_YPD HST3 Hughes00 -0.98 0.1038 54NRG1_H2O2Hirsc3-2 Angus-Hill_01 -0.98 0.1038 123RCS1_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 0.98 0.1038 52SWI4_YPD WT_TAF1_GCN5Huisinga04 -0.98 0.1039 154CIN5_YPD SIR3 Hughes00 0.98 0.1039 149GCR2_SM Dsds3 Keogh05 0.98 0.1039 50GLN3_RAPA RSC8 Mnaimneh_04 0.98 0.1039 68YAP6_H2O2Hi EAF5 Krogan04 0.98 0.1039 74PUT3_H2O2Lo IES6 Hughes00 -0.98 0.1039 88ROX1_YPD sas3D Durant06 0.98 0.104 50STP1_SM hat1_vs.YPH250Rosaleny05 0.98 0.104 66YAP7_H2O2Lo UBP8 Hughes00 0.98 0.104 150GCR2_SM hat2_vs._hat1Rosaleny05 -0.98 0.1041 51HSF1_H2O2Hi SIN3 Hughes00 0.98 0.1041 122SKN7_H2O2Lorpd3_del Sabet04 -0.98 0.1041 176

NDD1_YPD DT_WT Chitikila_02 0.98 0.1041 83CBF1_SM Ddep1 Keogh05 0.98 0.1042 243FKH1_YPD MOT1-14 Dasgupta02 -0.98 0.1042 141CIN5_YPD rsc30_null Angus-Hill_01 -0.98 0.1043 148GCN4_RAPA EPL1 Mnaimneh_04 0.98 0.1043 160SKN7_H2O2LoRAD6_haploid Hughes00 0.98 0.1043 183HSF1_H2O2LoHda1_del Bernstein02 0.98 0.1044 101YAP6_YPD SIN3 Hughes00 -0.98 0.1045 91YAP6_YPD SIR4 Hughes00 0.98 0.1045 91YAP7_H2O2Lo rsc30_null Angus-Hill_01 -0.98 0.1045 148YAP7_H2O2Lo SWD2 Mnaimneh_04 0.98 0.1046 152STE12_BUT14 ARD1 Hughes00 -0.98 0.1046 128STE12_BUT90 SSN6_haploid Hughes00 0.98 0.1046 77DAL82_RAPA esa1-414 Durant06 0.97 0.105 52PHO4_YPD H3KQ Sabet04 0.97 0.1051 70SWI5_YPD SWR1 Krogan04 0.97 0.1052 96YAP1_YPD ISW1_ISW2 Hughes00 -0.97 0.1052 71YAP6_YPD ISW1_ISW2 Hughes00 0.97 0.1052 90SWI6_YPD sir2 Meneghini03 -0.97 0.1053 150DAL81_RAPA DT_Null Chitikila_02 0.97 0.1053 91SKN7_YPD SIR3 Hughes00 0.97 0.1054 65PUT3_H2O2Lo hht2_K4914182327GMartin04 -0.97 0.1055 68ASH1_BUT14 snf2_minimal_medium_experimentSudarsanam00 0.97 0.1055 50SKN7_YPD Set1_del Bernstein02 0.97 0.1056 65CBF1_SM DT_V161R_L Chitikila_02 -0.97 0.1056 266STE12_BUT14 DT_V161R_K Chitikila_02 -0.97 0.1056 120STP1_SM htz1_del Mizuguch04 0.97 0.1057 68GCN4_RAPA EAF5 Krogan04 -0.97 0.1057 145GCN4_YPD WT_V71E Chitikila_02 -0.97 0.1057 66SWI4_YPD ino80 Attikum04 -0.97 0.1058 116GLN3_RAPA snf2_rich_medium_experimentSudarsanam00 0.97 0.1058 66YAP7_H2O2Lo WT_N69R Chitikila_02 -0.97 0.1058 138MGA1_YPD HDA1 Hughes00 -0.97 0.1058 62MBP1_H2O2Hi taf1-ts2_GCN5Huisinga04 0.97 0.1059 122SKN7_H2O2Hi ubp10 Orlandi04 0.97 0.106 54YAP7_H2O2Lo hht2_K4G Martin04 0.97 0.1061 120MCM1_Alpha taf1-ts2_gcn5 Huisinga04 0.97 0.1061 104DIG1_BUT14 taf1-ts2_GCN5Huisinga04 0.97 0.1061 59PHD1_BUT90 hat1D_taf1-ts2Durant06 0.97 0.1061 88GCR2_SM SWD2 Mnaimneh_04 0.97 0.1062 54UME6_YPD WT_V71E Chitikila_02 -0.97 0.1063 102HAP1_YPD SIN3 Hughes00 0.97 0.1064 139CIN5_H2O2Lo H3_1-28 Sabet04 0.97 0.1066 119YAP6_YPD swr1 Meneghini03 -0.97 0.1068 74STE12_Alpha Deaf3 Keogh05 -0.97 0.1068 105PHO4_YPD hat2_vs._YPH250Rosaleny05 -0.97 0.1069 68GCR2_SM rpd3_c.i. Fazzio01 -0.97 0.107 52CIN5_YPD htz1_sir2 Meneghini03 0.97 0.1071 148CIN5_H2O2Hi gcn5D_taf1-ts2Durant06 -0.96 0.1072 72MSN4_H2O2HiWT_Null_K Chitikila_02 0.96 0.1072 67GLN3_RAPA Dsin3 Keogh05 0.96 0.1073 58ACE2_YPD BUR6 Geisberg_01 0.96 0.1073 78STE12_YPD RSC8 Mnaimneh_04 0.96 0.1074 54

DAL82_RAPA hht2_K27G Martin04 0.96 0.1075 38SWI5_YPD hat2_vs._hat1Rosaleny05 -0.96 0.1076 92YAP6_H2O2Hi arp8 Attikum04 -0.96 0.1076 48STE12_Alpha UBP8 Hughes00 0.96 0.1076 115GLN3_RAPA EAF7 Krogan04 0.96 0.1077 65RTG3_RAPA WT_V161R_K Chitikila_02 -0.96 0.1077 48MBP1_H2O2LoDT_N69R Chitikila_02 -0.96 0.1077 52MBP1_YPD UBP8 Ingvarsdottir05 0.96 0.1078 122SKN7_YPD DT_V71R Chitikila_02 0.96 0.108 65SUT1_YPD Dsds3 Keogh05 -0.96 0.1081 61GLN3_RAPA sas3D Durant06 -0.96 0.1082 56YAP6_H2O2Hi WT_V161R_L Chitikila_02 0.96 0.1082 72YAP7_H2O2Lo WT_V161R_K Chitikila_02 -0.96 0.1082 139ACE2_YPD swi1_minimal_medium_experimentSudarsanam00 -0.96 0.1082 80SOK2_BUT14 WT_Null_K Chitikila_02 -0.96 0.1083 71STE12_YPD H3_1-28 Sabet04 -0.96 0.1084 51AFT2_H2O2Hi Drxt1 Keogh05 -0.96 0.1084 61TYE7_YPD WT_Null_L Chitikila_02 0.96 0.1086 52NRG1_H2O2Hitaf1-ts2_25C Huisinga04 0.96 0.1086 115RIM101_H2O2Loelp3D Durant06 -0.96 0.1086 40SKN7_H2O2Loisw2_rpd3 Fazzio01 -0.96 0.1086 181MSN4_RAPA Drpd3 Keogh05 -0.96 0.1087 46MGA1_YPD isw2_c.i. Fazzio01 0.96 0.1087 60DIG1_BUT14 SWR1 Krogan04 0.96 0.1088 61DIG1_BUT14 rpd3_H4KQ_v_H4KQSabet04 -0.96 0.1088 63MCM1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.96 0.1088 60MBP1_H2O2HiDT_V161R_L Chitikila_02 -0.96 0.1089 123STE12_Alpha SSD1-V Kaeberlein04 0.96 0.1089 114MBP1_YPD hat2_vs._hat1Rosaleny05 -0.96 0.1089 124MSN4_RAPA isw2_sin3_vs._sin3Fazzio01 0.96 0.109 53STP1_SM Drxt1 Keogh05 0.96 0.1091 66YAP6_H2O2Hi SWR1 Krogan04 -0.96 0.1092 72DIG1_BUT14 RPD3_haploid Hughes00 0.96 0.1092 63PUT3_H2O2Lo WT_V71R Chitikila_02 0.96 0.1094 79YAP1_YPD DT_Null Chitikila_02 0.96 0.1095 69DAL82_SM isw2_sin3_vs._sin3Fazzio01 -0.96 0.1096 50MBP1_H2O2LoDT_V71E Chitikila_02 -0.96 0.1096 55ACE2_YPD SIN3 Hughes00 0.96 0.1096 80MBP1_YPD ino80 Attikum04 0.96 0.1096 108SKN7_YPD rpd3_del Sabet04 -0.95 0.1097 62SKN7_H2O2Lohat2_vs._hat1Rosaleny05 -0.95 0.1097 179FKH2_YPD DT_V161R_L Chitikila_02 -0.95 0.1098 112GCN4_YPD hht2_K27G Martin04 -0.95 0.1098 65AFT2_H2O2Hi DT_V71R Chitikila_02 -0.95 0.1099 55SUM1_YPD VID21 Krogan04 -0.95 0.11 44MSN4_H2O2Hiisw2_sin3 Fazzio01 0.95 0.11 68RPN4_H2O2LoYNG2 Mnaimneh_04 0.95 0.1101 100PHD1_YPD taf1-ts2_gcn5 Huisinga04 0.95 0.1102 66FKH1_YPD sas3D_taf1-ts2Durant06 -0.95 0.1102 128NDD1_YPD hht2_K914182327GMartin04 0.95 0.1103 75SWI6_YPD isw2 Fazzio01 0.95 0.1104 148RCS1_H2O2LoMOT1-42 Dasgupta02 -0.95 0.1106 252REB1_YPD hht2_K914182327GMartin04 0.95 0.1108 125

XBP1_H2O2Lo ISW1_ISW2 Hughes00 0.95 0.1108 66DIG1_BUT14 isw2 Fazzio01 0.95 0.1108 63PUT3_H2O2Lo hht2_K914182327GMartin04 0.95 0.1109 68XBP1_H2O2Lo hht2_K914182327GMartin04 0.95 0.1109 45CIN5_H2O2Lo BUR6 Geisberg_01 0.95 0.111 121NRG1_YPD YNG2 Krogan04 0.95 0.111 67STP1_SM spt10_del Xu05 -0.95 0.1111 67RIM101_H2O2LoRAD6_haploid Hughes00 0.95 0.1111 53PUT3_H2O2Lo taf1-ts2_GCN5Huisinga04 0.95 0.1112 83YAP6_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 0.95 0.1113 79MCM1_YPD hpa2D Durant06 -0.95 0.1113 53MGA1_YPD swi1_rich_medium_experimentSudarsanam00 0.95 0.1113 62CIN5_YPD WT_TAF1_GCN5Huisinga04 -0.95 0.1114 150CIN5_H2O2Lo WT Durant06 -0.95 0.1114 117DAL81_RAPA elp3D Durant06 0.95 0.1115 76YAP7_H2O2Hi SWD2 Mnaimneh_04 0.95 0.1115 141NDD1_YPD snf2_minimal_medium_experimentSudarsanam00 -0.95 0.1115 85SKN7_YPD WT_TAF1_SPT3Huisinga04 0.95 0.1116 64YAP6_H2O2Hi HIR2 Hughes00 0.95 0.1116 77SWI6_YPD Drco1 Keogh05 0.95 0.1117 146UME6_YPD elp3D_taf1-ts2Durant06 0.95 0.1117 96AFT2_H2O2Hi BUR6 Geisberg_01 0.95 0.1117 57ROX1_YPD DT_V71R Chitikila_02 0.95 0.1118 65SKN7_YPD hht2_K4914182327GMartin04 0.95 0.1118 52ASH1_BUT14 SWD2 Mnaimneh_04 0.95 0.1118 50DAL82_SM taf1-ts2_spt3 Huisinga04 -0.95 0.1119 54SOK2_BUT14 hpa2D Durant06 -0.95 0.1119 52MSN4_RAPA swr1_del Mizuguch04 0.95 0.112 54XBP1_H2O2Lo MED2_haploid Hughes00 0.95 0.112 67AFT2_H2O2Lo isw2_rpd3_vs._rpd3Fazzio01 -0.95 0.1121 95PHD1_YPD delta_ssd1 Kaeberlein04 0.94 0.1123 66RCS1_H2O2Hi TUP1_haploid Hughes00 0.94 0.1123 52RIM101_H2O2Logcn5D Durant06 0.94 0.1124 47XBP1_H2O2Lo gcn5D_taf1-ts2Durant06 0.94 0.1125 58ABF1_YPD taf1-ts2_SPT3 Huisinga04 0.94 0.1126 250DAL82_SM WT_V71E Chitikila_02 -0.94 0.1126 50STP1_SM rpd3_H3dN_v_H3dNSabet04 -0.94 0.1126 67PUT3_H2O2Lo H3_1-28 Sabet04 0.94 0.1126 85GCN4_YPD SSD1-V Kaeberlein04 0.94 0.1127 75MGA1_YPD spt3 Huisinga04 0.94 0.1128 56OAF1_YPD H4KQ Sabet04 0.94 0.1128 54PHD1_YPD sir2 Meneghini03 0.94 0.1129 67MBP1_H2O2Hi swr1 Meneghini03 0.94 0.1129 108STE12_BUT90 WT_TAF1_SPT3Huisinga04 0.94 0.1129 73ABF1_YPD isw2_sin3 Fazzio01 0.94 0.1131 262SWI5_YPD RSC8 Mnaimneh_04 0.94 0.1131 102DAL82_SM isw2 Fazzio01 -0.94 0.1132 50MSN4_RAPA WT_Null_K Chitikila_02 0.94 0.1132 52ASH1_BUT14 DT_V161R_K Chitikila_02 -0.94 0.1132 48GCR2_SM Drco1 Keogh05 0.94 0.1133 52YAP7_H2O2Hi isw2 Fazzio01 0.94 0.1133 136YAP7_H2O2Lo HAT2 Hughes00 -0.94 0.1133 151MBP1_YPD 0.1%_MMS Attikum04 -0.94 0.1133 111

ABF1_YPD YAF9 Krogan04 -0.94 0.1134 256DAL81_RAPA VID21 Krogan04 0.94 0.1134 84ABF1_YPD H3_1-28 Sabet04 -0.94 0.1135 261RIM101_H2O2LoWT_V161R_K Chitikila_02 0.94 0.1136 48SKN7_H2O2Hi sin3 Fazzio01 -0.94 0.1137 95SOK2_BUT14 hht2_K27G Martin04 0.94 0.1137 46MGA1_YPD WT_TAF1_SPT3Huisinga04 -0.94 0.1137 57STP1_SM SWR1 Krogan04 0.94 0.1138 59STE12_BUT14 hht2K9131823GMartin04 0.94 0.1138 108MSN4_H2O2HiDT_V161E Chitikila_02 -0.94 0.1139 67RIM101_H2O2Loubp10 Orlandi04 0.94 0.1139 23CBF1_SM ume6 Fazzio01 0.94 0.114 272DIG1_Alpha rsc30_null Angus-Hill_01 -0.94 0.114 57ASH1_BUT14 DT_V161R_L Chitikila_02 -0.94 0.114 46SWI5_YPD sir4 Orlandi04 -0.94 0.1141 72DAL81_RAPA Set1_del Bernstein02 0.94 0.1141 94RIM101_H2O2Loswr1_del Mizuguch04 -0.94 0.1141 54NDD1_YPD rpd3 Fazzio01 0.94 0.1141 80HSF1_H2O2Hi SWR1 Krogan04 0.94 0.1142 110MBP1_H2O2HiMOT1-42 Dasgupta02 -0.94 0.1142 131RCS1_H2O2Hi WT_N69R Chitikila_02 0.94 0.1142 44UME6_YPD ISW1 Hughes00 0.94 0.1143 128SKN7_H2O2Loswr1_del Mizuguch04 0.94 0.1143 185CIN5_H2O2Lo taf1-ts2_GCN5Huisinga04 0.94 0.1144 116ROX1_YPD swr1_del Mizuguch04 -0.94 0.1145 66GLN3_RAPA Dsds3 Keogh05 -0.94 0.1145 60DAL82_SM WT_N69S Chitikila_02 -0.94 0.1146 48RIM101_H2O2LoMED2_haploid Hughes00 0.94 0.1146 53RIM101_H2O2Lorsc30_null Angus-Hill_01 -0.94 0.1146 52ACE2_YPD MOT1-14 Dasgupta02 0.94 0.1146 80CBF1_SM WT_N69S Chitikila_02 -0.94 0.1147 246CBF1_SM Drxt2 Keogh05 0.94 0.1147 247YAP6_H2O2Hi ubp10sir4 Orlandi04 -0.94 0.1147 39XBP1_H2O2Lo SPT3 Ingvarsdottir05 -0.94 0.1147 62SKN7_H2O2Hi gcn5 Huisinga04 -0.93 0.1151 91UME6_YPD PCH1 Hughes00 -0.93 0.1152 130PUT3_H2O2Lo Ddep1 Keogh05 -0.93 0.1152 82DAL82_SM hpa2D_taf1-ts2Durant06 0.93 0.1153 42RCS1_H2O2Hi SAP30 Hughes00 0.93 0.1153 52XBP1_H2O2Lo WT_Null_K Chitikila_02 -0.93 0.1153 66PHD1_BUT90 swi1_rich_medium_experimentSudarsanam00 0.93 0.1153 106TYE7_YPD arp8 Attikum04 -0.93 0.1154 50YAP7_H2O2Hi Dsin3 Keogh05 0.93 0.1154 116ROX1_YPD SWC6_(VPS71)Krogan04 -0.93 0.1155 57SUT1_YPD SAP30 Hughes00 -0.93 0.1155 68ACE2_YPD DT_V161R_K Chitikila_02 -0.93 0.1155 77RLM1_YPD swi1_minimal_medium_experimentSudarsanam00 0.93 0.1157 54CBF1_SM Dpho23 Keogh05 0.93 0.1157 276DAL82_RAPA SIR3 Hughes00 0.93 0.1157 56REB1_YPD esa1-414 Durant06 -0.93 0.1158 129STE12_YPD esa1-414_taf1-ts2Durant06 0.93 0.1158 48NRG1_YPD SAP30 Hughes00 -0.93 0.1158 72RIM101_H2O2Lorpd3_del Sabet04 -0.93 0.116 44

MSN2_H2O2HiWT Durant06 -0.93 0.1161 76HSF1_H2O2LoSAP30 Hughes00 0.93 0.1161 99MBP1_H2O2LoDrxt1 Keogh05 -0.93 0.1164 57PHO4_YPD hat1_vs.YPH250Rosaleny05 0.93 0.1165 68TYE7_YPD sir4 Orlandi04 -0.93 0.1165 46HAP4_YPD SIR2 Hughes00 0.93 0.1167 66REB1_YPD isw2_ume6 Fazzio01 0.93 0.1168 142FKH2_H2O2Hi H4KQ Sabet04 0.93 0.1168 103MBP1_H2O2Hi sas3D_taf1-ts2Durant06 0.93 0.1168 121CIN5_H2O2Lo ARP4 Mnaimneh_04 0.93 0.1168 127SUT1_YPD HTZ1 Krogan04 -0.93 0.117 63MSN2_H2O2Hiswi1_rich_medium_experimentSudarsanam00 0.93 0.117 78HAP4_YPD swi1_minimal_medium_experimentSudarsanam00 -0.93 0.117 67SUT1_YPD hht2K9131823GMartin04 0.93 0.1171 49XBP1_H2O2Lo hat1_vs.YPH250Rosaleny05 0.93 0.1171 59CIN5_H2O2Hi H3_1-28 Sabet04 0.93 0.1172 74MSN4_H2O2HiRPD3_haploid Hughes00 0.93 0.1173 69PUT3_H2O2Lo hda1_del Bernstein_00_affydeletions0.93 0.1173 79AFT2_H2O2Hi rpd3_c.i. Fazzio01 -0.93 0.1174 58FKH2_H2O2Hi htz1_del Mizuguch04 0.93 0.1174 106NRG1_H2O2HiWT_TAF1_GCN5Huisinga04 0.93 0.1174 122UME6_H2O2Higcn5_KQL Huisinga04 0.92 0.1175 91PHO4_YPD hos3_del Bernstein_00_affydeletions-0.92 0.1176 68SOK2_BUT14 SWD2 Mnaimneh_04 0.92 0.1176 72SWI5_YPD WT_V71R Chitikila_02 -0.92 0.1177 89TYE7_YPD gcn5D Durant06 0.92 0.1177 47HSF1_H2O2Logcn5_KQL Huisinga04 0.92 0.1177 77RIM101_H2O2Losap30_del Bernstein_00_affydeletions-0.92 0.1178 39SUT1_YPD HIR2 Hughes00 0.92 0.1179 69REB1_H2O2Hi WT_Null_K Chitikila_02 0.92 0.1179 54STE12_BUT14 snf2_rich_medium_experimentSudarsanam00 -0.92 0.1179 128NRG1_YPD HTZ1 Krogan04 -0.92 0.1179 65MSN2_H2O2HiIES6 Hughes00 0.92 0.118 77MCM1_YPD isw2_rpd3 Fazzio01 0.92 0.118 73CIN5_YPD IOC4 Hughes00 -0.92 0.1181 147RLM1_YPD hpa2D_taf1-ts2Durant06 0.92 0.1182 42NRG1_H2O2HiDT_V71R Chitikila_02 0.92 0.1182 115RLM1_YPD hmr Meneghini03 -0.92 0.1184 51YAP7_H2O2Hi WT_V161E Chitikila_02 -0.92 0.1184 137CIN5_H2O2Lo SWR1 Krogan04 -0.92 0.1184 109REB1_YPD ZDS1 Hughes00 -0.92 0.1185 142CBF1_SM EAF7 Krogan04 0.92 0.1185 252STP1_SM 0.1%_MMS Attikum04 0.92 0.1185 51AFT2_H2O2Hi rsc30_null Angus-Hill_01 -0.92 0.1185 59MBP1_H2O2Loesa1-414_taf1-ts2Durant06 -0.92 0.1185 56STE12_YPD DT_V161R_K Chitikila_02 -0.92 0.1186 46DAL82_SM rpd3_H4KQ_v_H4KQSabet04 -0.92 0.1188 50UME6_YPD rpd3_c.i. Fazzio01 0.92 0.1189 125YAP6_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 -0.92 0.1189 71DAL82_SM ISW1 Hughes00 0.92 0.119 55STP1_SM hat2_vs._hat1Rosaleny05 -0.92 0.119 65MSN4_RAPA hht2_K49141823GMartin04 -0.92 0.119 33CIN5_H2O2Hi hht2_K27G Martin04 -0.92 0.1191 50

RCS1_H2O2Hi rpd3_H3dN_v_H3dNSabet04 0.92 0.1192 50NDD1_YPD spt10 Eriksson05 -0.92 0.1192 85UME6_YPD taf1-ts2_SPT3 Huisinga04 0.92 0.1193 118YAP6_H2O2Hi gcn5 Huisinga04 0.92 0.1193 74YAP6_YPD DT_Null Chitikila_02 -0.92 0.1194 89STE12_BUT14 hpa2D Durant06 -0.92 0.1194 103HAP4_YPD Dsap30 Keogh05 -0.92 0.1194 60SUM1_YPD WT_F182V Chitikila_02 -0.92 0.1195 41ASH1_BUT14 rpd3_del Sabet04 0.92 0.1195 47MCM1_YPD htz1_hmr Meneghini03 0.92 0.1195 77SKN7_YPD HST3 Hughes00 0.92 0.1196 66CIN5_H2O2Lo taf1-ts2_gcn5_KQLHuisinga04 0.92 0.1196 107HAP1_YPD ubp10 Orlandi04 0.92 0.1196 105YAP6_H2O2Lo MOT1-42 Dasgupta02 0.92 0.1198 58CIN5_H2O2Lo H4_2-26 Sabet04 0.92 0.1199 119ASH1_BUT14 Hda1_del Bernstein02 0.92 0.12 49UME6_YPD spt3_E240K Huisinga04 -0.92 0.1201 109GCN4_RAPA Set1_del Bernstein02 0.92 0.1201 158RCS1_H2O2LoSWD2 Mnaimneh_04 0.92 0.1201 259ASH1_BUT14 delta_ssd1 Kaeberlein04 0.92 0.1202 49YAP1_YPD isw2_sin3 Fazzio01 -0.91 0.1203 68MBP1_H2O2LoHIR2 Hughes00 -0.91 0.1203 57MCM1_Alpha Drxt1 Keogh05 -0.91 0.1203 106DIG1_BUT14 0.1%_MMS Attikum04 -0.91 0.1203 54FKH1_YPD taf1-ts2_spt3 Huisinga04 -0.91 0.1203 138SOK2_BUT14 taf1-ts2_25C Huisinga04 0.91 0.1203 66DAL82_RAPA RAD6_haploid Hughes00 0.91 0.1204 55RLM1_YPD swi1_rich_medium_experimentSudarsanam00 -0.91 0.1205 54SKN7_H2O2HiHda1_del Bernstein02 0.91 0.1205 96SKN7_H2O2Hi htz1_hmr Meneghini03 0.91 0.1206 96HAP4_YPD ISW1_ISW2 Hughes00 0.91 0.1207 67MBP1_YPD WT_Null_K Chitikila_02 0.91 0.1207 122ASH1_BUT14 ino80_del Mizuguch04 0.91 0.1208 50ASH1_BUT14 DT_Null Chitikila_02 0.91 0.1208 48UME6_YPD _SWC2_(VPS72)Krogan04 0.91 0.1209 111YAP7_H2O2Hi YAF9 Krogan04 -0.91 0.1209 134CIN5_H2O2Lo ISW1 Hughes00 -0.91 0.1209 126STE12_BUT14 rpd3_H3dN_v_H3dNSabet04 -0.91 0.1209 122AFT2_H2O2Hi ZDS1 Hughes00 0.91 0.121 59HSF1_H2O2Hi hht2_K914182327GMartin04 -0.91 0.121 97CIN5_H2O2Hi rpd3 Fazzio01 -0.91 0.1212 79YAP7_H2O2Hi SPT3 Ingvarsdottir05 0.91 0.1212 125DAL82_SM ume6_del Bernstein_00_affydeletions0.91 0.1213 48SUM1_YPD WT_V161R_K Chitikila_02 0.91 0.1214 50RCS1_H2O2Loisw2_rpd3 Fazzio01 0.91 0.1214 252NRG1_YPD DT_V71R Chitikila_02 0.91 0.1214 65OAF1_YPD DM_vs._YPH250Rosaleny05 0.91 0.1214 53YAP6_H2O2Hi hht2_K4914182327GMartin04 -0.91 0.1215 49RTG3_RAPA ISW2 Hughes00 0.91 0.1216 51RCS1_H2O2LoMOT1-14 Dasgupta02 -0.91 0.1217 250DAL82_RAPA spt10_del Xu05 -0.91 0.1218 56GCN4_RAPA elp3D Durant06 0.91 0.1218 135MSN4_RAPA arp8 Attikum04 0.91 0.1218 29

CIN5_H2O2Hi UBP8 Ingvarsdottir05 0.91 0.1218 73NRG1_YPD hat2_vs._YPH250Rosaleny05 -0.91 0.1218 65SWI4_YPD IES6 Hughes00 -0.91 0.1219 156MCM1_YPD SWR1 Krogan04 0.91 0.1219 74ROX1_YPD WT_V161E Chitikila_02 0.91 0.122 67UME6_YPD UBP8 Ingvarsdottir05 0.91 0.122 118MGA1_YPD BUR6 Geisberg_01 -0.91 0.122 60NDD1_YPD isw2_rpd3 Fazzio01 0.91 0.122 79YAP1_YPD Set1_del Bernstein02 0.91 0.1221 70GCN4_SM rpd3_c.i. Fazzio01 -0.91 0.1221 182ROX1_YPD rpd3_H3dN_v_H3dNSabet04 0.91 0.1222 58ACE2_YPD WT_V71E Chitikila_02 -0.91 0.1222 67GCR2_SM SGF11 Ingvarsdottir05 0.91 0.1223 50STP1_SM ume6 Fazzio01 0.91 0.1224 67PHO4_YPD spt10_del Xu05 0.91 0.1225 71YAP1_YPD Dsap30 Keogh05 0.91 0.1225 69STE12_Alpha swr1 Meneghini03 -0.91 0.1225 91OAF1_YPD DT_V161R_K Chitikila_02 -0.91 0.1225 54ACE2_YPD DT_WT Chitikila_02 -0.91 0.1226 74NRG1_H2O2Hirpd3 Fazzio01 -0.91 0.1227 123MCM1_YPD DM_vs._YPH250Rosaleny05 0.91 0.1227 69TYE7_YPD ino80 Attikum04 -0.91 0.1229 49TYE7_YPD RPD3_haploid Hughes00 -0.91 0.1229 54CIN5_YPD WT_N69S Chitikila_02 -0.91 0.1229 139STE12_BUT14 RSC8 Mnaimneh_04 0.91 0.1229 128RTG3_RAPA htz1_sir2 Meneghini03 0.91 0.123 50REB1_H2O2Hi ZDS1 Hughes00 -0.91 0.123 59STE12_BUT14 DT_N69S Chitikila_02 -0.91 0.123 109YAP6_H2O2Lo HTZ1 Krogan04 -0.9 0.1232 55TYE7_YPD IOC4 Hughes00 -0.9 0.1233 56PUT3_H2O2Lo spt10_del Xu05 0.9 0.1233 87CBF1_SM H4KQ Sabet04 0.9 0.1234 271CIN5_H2O2Hi hht2K9131823GMartin04 0.9 0.1234 52SOK2_BUT14 DT_V71R Chitikila_02 0.9 0.1235 68GCR2_SM YNG2 Mnaimneh_04 0.9 0.1236 54YAP6_H2O2Lo WT_F182V Chitikila_02 -0.9 0.1237 44SOK2_BUT14 WT_V71R Chitikila_02 -0.9 0.1237 69MSN4_H2O2HiIES6 Hughes00 0.9 0.1238 69RCS1_H2O2LoBUR6 Geisberg_01 -0.9 0.1238 246GLN3_RAPA IES6 Hughes00 -0.9 0.1239 68HSF1_H2O2Hi gcn5_KQL Huisinga04 -0.9 0.1239 100REB1_YPD WT_V161E Chitikila_02 0.9 0.1241 129SUM1_YPD ino80_del Mizuguch04 0.9 0.1241 59HSF1_H2O2LoDrco1 Keogh05 -0.9 0.1241 94HAP4_YPD HTZ1 Krogan04 0.9 0.1241 55ASH1_BUT14 HDA1 Hughes00 -0.9 0.1242 50CBF1_SM IES6 Hughes00 -0.9 0.1243 279CIN5_YPD htz1_hmr Meneghini03 -0.9 0.1244 149STE12_YPD WT_Null_L Chitikila_02 0.9 0.1245 48DIG1_Alpha gcn5 Huisinga04 -0.9 0.1245 56MCM1_Alpha sin3 Fazzio01 0.9 0.1245 104MCM1_Alpha MOT1-14 Dasgupta02 0.9 0.1246 105AFT2_H2O2Lo DT_V161R_K Chitikila_02 0.9 0.1247 96

HSF1_H2O2LoSWR1 Krogan04 0.9 0.1247 90UME6_H2O2Hiswi1_minimal_medium_experimentSudarsanam00 0.9 0.1248 102ASH1_BUT14 SAP30 Hughes00 0.9 0.1248 50DAL82_SM WT_Null_L Chitikila_02 0.9 0.1249 54GLN3_RAPA ino80 Attikum04 0.9 0.1249 55REB1_H2O2Hi RAD6_haploid Hughes00 0.9 0.1249 58YAP1_YPD rpd3 Fazzio01 -0.9 0.125 68RCS1_H2O2Loisw2_c.i._rpd3_c.i.Fazzio01 0.9 0.125 252SUM1_YPD Hda1_del Bernstein02 -0.9 0.1251 57SUT1_YPD _SWC2_(VPS72)Krogan04 0.9 0.1254 65SWI4_YPD DT_N69R Chitikila_02 -0.9 0.1254 145YAP1_YPD DM_vs._YPH250Rosaleny05 0.9 0.1254 69ASH1_BUT14 sin3_del Bernstein_00_affydeletions-0.9 0.1256 42SWI4_YPD Drxt1 Keogh05 -0.9 0.1258 154YAP1_YPD BUR6 Geisberg_01 0.89 0.1259 68UME6_YPD MED2_haploid Hughes00 -0.89 0.1261 130GLN3_RAPA Rpd3_del Bernstein02 0.89 0.1261 66PHD1_BUT90 DT_N69S Chitikila_02 -0.89 0.1262 97AFT2_H2O2Lo UBP8 Hughes00 0.89 0.1263 96SWI4_YPD SIR1 Hughes00 0.89 0.1266 153GLN3_RAPA Dsap30 Keogh05 -0.89 0.1266 64MSN4_RAPA SIR3 Hughes00 -0.89 0.1266 54CIN5_H2O2Hi DT_V161R_L Chitikila_02 0.89 0.1266 78ASH1_BUT14 UBP8 Ingvarsdottir05 0.89 0.1266 44ASH1_BUT14 isw2_c.i._rpd3_c.i.Fazzio01 0.89 0.1266 49OAF1_YPD WT_F182V Chitikila_02 0.89 0.1266 49MBP1_H2O2Lotaf1-ts2 Durant06 -0.89 0.1267 56SWI6_YPD SIR4 Hughes00 0.89 0.1268 153REB1_H2O2Hi hht2_K49141823GMartin04 0.89 0.1268 49GCR2_SM WT_TAF1_GCN5Huisinga04 -0.89 0.127 54PUT3_H2O2Lo SIN3 Hughes00 0.89 0.127 86REB1_YPD delta_ssd1 Kaeberlein04 0.89 0.1271 142SUM1_YPD RAD6_haploid Hughes00 0.89 0.1271 58YAP6_H2O2Lo ISW1 Hughes00 0.89 0.1273 58SUM1_YPD Dpho23 Keogh05 -0.89 0.1274 58DAL82_SM RSC8 Mnaimneh_04 0.89 0.1274 55REB1_H2O2Hi WT_TAF1_GCN5Huisinga04 -0.89 0.1274 57YAP6_H2O2Lo DT_N69S Chitikila_02 -0.89 0.1275 53UME6_H2O2HiWT_N69S Chitikila_02 0.89 0.1276 91YAP6_H2O2Hi ino80_del Mizuguch04 -0.89 0.1276 79MSN4_RAPA WT_V161R_L Chitikila_02 0.89 0.1277 50ASH1_BUT14 ubp10 Orlandi04 0.89 0.1279 31MSN4_RAPA gcn5D_taf1-ts2Durant06 0.89 0.128 45CIN5_H2O2Lo SIR4 Hughes00 -0.89 0.1281 126YAP6_H2O2Hi taf1-ts2_gcn5 Huisinga04 -0.89 0.1282 73FKH1_YPD EAF5 Krogan04 -0.89 0.1282 126STE12_BUT90 VID21 Krogan04 0.89 0.1282 70DAL82_RAPA ubp10 Orlandi04 -0.89 0.1283 33MBP1_H2O2LoYAF9 Krogan04 0.89 0.1283 56UME6_YPD gcn5_KQL Huisinga04 0.89 0.1284 115DAL82_RAPA SSN6_haploid Hughes00 0.89 0.1284 52NDD1_YPD YAF9 Krogan04 0.89 0.1284 80YAP6_YPD DT_V71E Chitikila_02 -0.89 0.1285 88

XBP1_H2O2Lo hht2_K27G Martin04 -0.89 0.1285 44DIG1_Alpha WT_Null_L Chitikila_02 0.89 0.1285 54CBF1_SM WT_V71E Chitikila_02 -0.89 0.1286 239RCS1_H2O2Hi UBP8 Ingvarsdottir05 0.89 0.1286 46RIM101_H2O2Logcn5D_taf1-ts2Durant06 0.89 0.1286 47TYE7_YPD SWC6_(VPS71)Krogan04 -0.89 0.1287 52SWI6_YPD hat2_vs._hat1Rosaleny05 -0.89 0.1288 146UME6_H2O2Hi_SWC2_(VPS72)Krogan04 0.89 0.1288 85MBP1_YPD TAF2 Mnaimneh_04 0.89 0.1288 130CIN5_H2O2Lo DT_Null Chitikila_02 -0.88 0.1289 121HSF1_H2O2LoSIN3 Hughes00 0.88 0.129 100FKH2_YPD rpd3_H3dN_v_H3dNSabet04 0.88 0.129 119MGA1_YPD WT_V71R Chitikila_02 0.88 0.129 53MBP1_YPD hat1D_taf1-ts2Durant06 -0.88 0.1292 105RTG3_RAPA _SWC2_(VPS72)Krogan04 0.88 0.1293 47RTG3_RAPA isw2_c.i. Fazzio01 -0.88 0.1293 51HSF1_H2O2Hi SSD1-V Kaeberlein04 0.88 0.1293 124CIN5_H2O2Lo gcn5D Durant06 -0.88 0.1294 100STP1_SM hda1_del Bernstein_00_affydeletions-0.88 0.1295 64AFT2_H2O2Hi hht2K9131823GMartin04 0.88 0.1295 45AFT2_H2O2Hi YNG2 Krogan04 0.88 0.1295 60MGA1_YPD hat2_vs._hat1Rosaleny05 0.88 0.1296 58RIM101_H2O2Loelp3D_taf1-ts2Durant06 -0.88 0.1297 35GCN4_SM gcn5D Durant06 0.88 0.1298 173GLN3_RAPA RPD3_haploid Hughes00 0.88 0.1298 63RIM101_H2O2Losnf2_minimal_medium_experimentSudarsanam00 0.88 0.1298 54YAP6_H2O2Lo DT_N69R Chitikila_02 -0.88 0.1299 53ROX1_YPD snf2_minimal_medium_experimentSudarsanam00 0.88 0.1301 67CIN5_H2O2Hi SPT8 Ingvarsdottir05 -0.88 0.1301 70SOK2_BUT14 sas3D Durant06 -0.88 0.1301 55SKN7_YPD DT_WT Chitikila_02 -0.88 0.1302 64RLM1_YPD sas3D Durant06 0.88 0.1305 48MBP1_H2O2LoH4KQ Sabet04 -0.88 0.1305 56SOK2_BUT14 MED2_haploid Hughes00 -0.88 0.1305 71DAL82_RAPA DT_Null Chitikila_02 -0.88 0.1307 55CIN5_YPD rsc3-2 Angus-Hill_01 0.88 0.1309 148DIG1_BUT14 swr1_del Mizuguch04 0.88 0.131 63MSN2_H2O2HiHDA1 Hughes00 0.88 0.1311 77SOK2_BUT14 taf1-ts2_SPT3 Huisinga04 0.88 0.1312 69SOK2_BUT14 taf1-ts2_GCN5Huisinga04 0.88 0.1313 68YAP6_YPD DT_V161R_L Chitikila_02 0.88 0.1314 86RIM101_H2O2LoH4_2-26 Sabet04 0.88 0.1314 44ABF1_YPD Dsap30 Keogh05 0.88 0.1315 252MBP1_YPD elp3D_taf1-ts2Durant06 0.88 0.1316 109OAF1_YPD H4_2-26 Sabet04 0.88 0.1316 55CIN5_H2O2Hi taf1-ts2_25C Huisinga04 -0.88 0.1317 75XBP1_H2O2Lo Drco1 Keogh05 0.88 0.1318 64PHO4_YPD DT_WT Chitikila_02 -0.87 0.1319 68SUT1_YPD MOT1-42 Dasgupta02 0.87 0.1319 69CIN5_H2O2Lo Deaf3 Keogh05 -0.87 0.1319 118SUM1_YPD htz1_sir2 Meneghini03 -0.87 0.132 56YAP6_H2O2Lo SIR1 Hughes00 -0.87 0.1321 58ABF1_YPD HST3 Hughes00 -0.87 0.1322 266

YAP7_H2O2Hi ZDS1 Hughes00 0.87 0.1322 139YAP7_H2O2Hi DM_vs._YPH250Rosaleny05 0.87 0.1323 136FKH1_YPD WT_V71R Chitikila_02 -0.87 0.1323 123OAF1_YPD SIN3 Hughes00 0.87 0.1323 59DAL81_RAPA Ddep1 Keogh05 0.87 0.1324 89AFT2_H2O2Lo isw2 Fazzio01 0.87 0.1324 95STE12_BUT90 WT_V161R_L Chitikila_02 -0.87 0.1324 73NDD1_YPD Set1_del Bernstein02 0.87 0.1324 84YAP7_H2O2Hi YNG2 Mnaimneh_04 0.87 0.1326 141DIG1_BUT14 hht2_K4G Martin04 -0.87 0.1326 55HAP4_YPD taf1-ts2_SPT3 Huisinga04 0.87 0.1327 64MGA1_YPD DT_V161R_L Chitikila_02 0.87 0.1327 58ABF1_YPD swr1 Meneghini03 0.87 0.1328 227DAL81_RAPA HST3 Hughes00 -0.87 0.1328 95UME6_H2O2HiEAF5 Krogan04 -0.87 0.1328 87RLM1_YPD SWC6_(VPS71)Krogan04 0.87 0.1332 51STP1_SM rpd3_H4KQ_v_H4KQSabet04 -0.87 0.1332 67CIN5_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 -0.87 0.1332 74SUM1_YPD hht2K9131823GMartin04 0.87 0.1336 27MSN4_RAPA spt10_del Xu05 -0.87 0.1336 54YAP6_H2O2Lo hht2K9131823GMartin04 0.87 0.1336 34CBF1_SM htz1_del Mizuguch04 0.87 0.1337 278DAL82_RAPA snf2_minimal_medium_experimentSudarsanam00 -0.87 0.1337 56RCS1_H2O2Hi WT_TAF1_GCN5Huisinga04 0.87 0.1337 51SKN7_H2O2HiRAD6_haploid Hughes00 0.87 0.1337 97GCN4_RAPA WT Durant06 -0.87 0.1338 153YAP6_H2O2Hi esa1-414_taf1-ts2Durant06 -0.87 0.1338 64REB1_H2O2Hi rpd3_H3dN_v_H3dNSabet04 -0.87 0.1339 57XBP1_H2O2Lo gcn5 Huisinga04 0.87 0.134 64FKH1_YPD SAP30 Hughes00 0.87 0.1341 140NDD1_YPD IES6 Hughes00 0.87 0.1341 84SKN7_YPD hht2K9131823GMartin04 0.87 0.1344 52YAP7_H2O2Hi WT_Null_L Chitikila_02 -0.87 0.1344 132HAP1_YPD WT Durant06 -0.87 0.1344 138ROX1_YPD EPL1 Mnaimneh_04 -0.87 0.1345 67YAP1_YPD EAF7 Krogan04 0.87 0.1345 67YAP6_H2O2Lo hht2_K4914182327GMartin04 -0.87 0.1345 34TYE7_YPD gcn5 Huisinga04 -0.87 0.1346 53GCN4_YPD H4KQ Sabet04 0.87 0.1346 75RLM1_YPD Drpd3 Keogh05 -0.87 0.1347 51YAP6_H2O2Lo SGF11 Ingvarsdottir05 0.87 0.1347 49FKH1_YPD htz1 Meneghini03 0.87 0.1347 139SKN7_YPD SAP30 Hughes00 0.87 0.1348 66SKN7_YPD hht2_K4G Martin04 0.87 0.1348 51RPN4_H2O2Lospt10 Eriksson05 -0.87 0.1348 99DIG1_BUT14 VID21 Krogan04 0.87 0.1348 58CBF1_SM rsc3-2 Angus-Hill_01 0.86 0.1349 273MBP1_H2O2LoSIR3 Hughes00 -0.86 0.1349 57XBP1_H2O2Lo arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.86 0.1349 42DIG1_Alpha Drxt2 Keogh05 -0.86 0.1349 59STE12_BUT90 EAF7 Krogan04 0.86 0.1349 75ACE2_YPD taf1-ts2_SPT3 Huisinga04 0.86 0.1349 70STE12_YPD taf1-ts2_gcn5_KQLHuisinga04 0.86 0.135 37

DAL82_SM IOC4 Hughes00 -0.86 0.135 55RTG3_RAPA PCH1 Hughes00 0.86 0.135 50RTG3_RAPA YNG2 Krogan04 -0.86 0.135 47STE12_Alpha ino80 Attikum04 -0.86 0.1351 85DIG1_BUT14 Dume1 Keogh05 -0.86 0.1357 59DAL82_SM spt3_E240K Huisinga04 -0.86 0.1358 51MGA1_YPD ARD1 Hughes00 0.86 0.1358 62SUT1_YPD PCH1 Hughes00 0.86 0.1359 69UME6_YPD H3KQ Sabet04 0.86 0.1359 128NRG1_H2O2Hiubp10sir4 Orlandi04 0.86 0.1359 73RIM101_H2O2LoISW1_ISW2 Hughes00 0.86 0.1361 53FKH1_YPD DT_WT Chitikila_02 -0.86 0.1361 131GCN4_YPD MOT1-42 Dasgupta02 0.86 0.1361 75PHO4_YPD ino80_del Mizuguch04 0.86 0.1362 71RIM101_H2O2LoARP4 Mnaimneh_04 0.86 0.1362 54YAP1_YPD isw2_rpd3 Fazzio01 -0.86 0.1363 68STE12_BUT14 ume6 Fazzio01 -0.86 0.1364 127SWI5_YPD swr1 Meneghini03 0.86 0.1367 71FKH1_YPD Dsin3 Keogh05 0.86 0.1367 118MBP1_H2O2Hi ISW1_ISW2 Hughes00 -0.86 0.1368 133STE12_Alpha elp3D Durant06 -0.86 0.1368 87RTG3_RAPA rsc3-2 Angus-Hill_01 0.86 0.1369 51XBP1_H2O2Lo snf2_rich_medium_experimentSudarsanam00 0.86 0.1369 68YAP7_H2O2Hi Dpho23 Keogh05 0.86 0.137 141ROX1_YPD WT Durant06 -0.86 0.1371 62HSF1_H2O2Hi BUR6 Geisberg_01 0.86 0.1371 119ASH1_BUT14 rpd3 Fazzio01 0.86 0.1373 49SKN7_H2O2Hi 0.1%_MMS Attikum04 -0.86 0.1374 75YAP1_YPD _SWC2_(VPS72)Krogan04 0.86 0.1377 68CIN5_H2O2Hi BUR6 Geisberg_01 0.86 0.1377 75RCS1_H2O2Hi sin3 Fazzio01 -0.86 0.1377 50UME6_YPD ubp10sir4 Orlandi04 -0.86 0.1378 70MSN2_H2O2HiZDS1 Hughes00 0.86 0.138 76GCN4_YPD BUR6 Geisberg_01 -0.86 0.138 73TYE7_YPD SGF11 Ingvarsdottir05 0.85 0.1381 47SKN7_H2O2Lorpd3_H3dN_v_H3dNSabet04 0.85 0.1382 177DAL82_RAPA taf1-ts2_gcn5 Huisinga04 0.85 0.1383 54HAP4_YPD H3KQ Sabet04 0.85 0.1384 62SWI6_YPD MOT1-42 Dasgupta02 -0.85 0.1386 153AFT2_H2O2Lo H3_1-28 Sabet04 0.85 0.1386 92STE12_BUT14 Hda1_del Bernstein02 0.85 0.1386 126XBP1_H2O2Lo hht2_K4914182327GMartin04 0.85 0.1387 44GCN4_SM WT_TAF1_SPT3Huisinga04 0.85 0.1388 180STP1_SM EPL1 Mnaimneh_04 0.85 0.1388 68GCN4_YPD VID21 Krogan04 -0.85 0.1388 68YAP1_YPD IES6 Hughes00 -0.85 0.1389 72GCR2_SM taf1-ts2_spt3 Huisinga04 -0.85 0.1389 54GCR2_SM H3_1-28 Sabet04 -0.85 0.1389 54RCS1_H2O2LoTAF2 Mnaimneh_04 0.85 0.1389 259MCM1_YPD spt3 Huisinga04 0.85 0.1389 76DAL82_SM ARP4 Mnaimneh_04 0.85 0.1391 55NRG1_H2O2HiSWR1 Krogan04 0.85 0.1391 116STE12_YPD ume6_del Bernstein_00_affydeletions-0.85 0.1392 50

DAL82_SM rsc30_null Angus-Hill_01 -0.85 0.1392 54ABF1_YPD spt10_del Xu05 0.85 0.1393 265ROX1_YPD DT_Null Chitikila_02 -0.85 0.1393 67CIN5_YPD ume6 Fazzio01 -0.85 0.1393 148ROX1_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.85 0.1394 67ABF1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.85 0.1395 230SWI6_YPD ume6_del Bernstein_00_affydeletions-0.85 0.1395 145SWI6_YPD hos3_del Bernstein_00_affydeletions0.85 0.1395 143SKN7_H2O2HiDT_V161R_K Chitikila_02 0.85 0.1396 97DAL81_RAPA ZDS1 Hughes00 0.85 0.1397 94SKN7_H2O2Hi hmr Meneghini03 -0.85 0.1397 96XBP1_H2O2Lo HST3 Hughes00 0.85 0.1397 66MBP1_YPD IES6 Hughes00 -0.85 0.1397 130MSN2_H2O2HiWT_TAF1_GCN5Huisinga04 -0.85 0.1398 78ABF1_YPD WT_TAF1_SPT3Huisinga04 0.85 0.1399 255PUT3_H2O2Lo WT_N69R Chitikila_02 0.85 0.1399 78RIM101_H2O2LoDT_WT Chitikila_02 -0.85 0.1399 51ROX1_YPD hht2_K49141823GMartin04 -0.85 0.14 43PHD1_YPD SGF11 Ingvarsdottir05 0.85 0.1401 56PUT3_H2O2Lo WT_F182V Chitikila_02 0.85 0.1401 74ROX1_YPD WT_N69S Chitikila_02 0.85 0.1402 66MGA1_YPD hht2_K914182327GMartin04 -0.85 0.1402 47RTG3_RAPA gcn5D_taf1-ts2Durant06 0.85 0.1403 50FKH2_H2O2Hi taf1-ts2_GCN5Huisinga04 0.85 0.1403 98HAP1_YPD hht2_K49141823GMartin04 0.85 0.1403 119FKH2_YPD Dsap30 Keogh05 0.85 0.1404 118HAP4_YPD _SWC2_(VPS72)Krogan04 0.85 0.1405 58MCM1_YPD Drxt1 Keogh05 -0.85 0.1406 77PHD1_YPD taf1-ts2_spt3_E240KHuisinga04 -0.85 0.1407 61MCM1_YPD ARD1 Hughes00 -0.85 0.1407 76STE12_YPD spt3 Huisinga04 -0.85 0.1409 49CIN5_YPD DT_V161R_L Chitikila_02 0.85 0.1409 146DIG1_BUT14 DT_N69S Chitikila_02 0.85 0.1409 51DIG1_Alpha MOT1-42 Dasgupta02 0.85 0.141 59DAL82_SM isw2_c.i._rpd3_c.i.Fazzio01 -0.85 0.1411 50FKH2_YPD elp3D Durant06 0.85 0.1411 100FKH2_H2O2Hi H3KQ Sabet04 -0.85 0.1412 102STE12_Alpha SPT3 Ingvarsdottir05 -0.85 0.1412 102STE12_BUT14 WT_Null_K Chitikila_02 0.84 0.1414 122YAP6_H2O2Hi Dsds3 Keogh05 -0.84 0.1415 73DIG1_BUT14 SWD2 Mnaimneh_04 0.84 0.1415 63MGA1_YPD Dume1 Keogh05 -0.84 0.1416 59SWI5_YPD rpd3_c.i. Fazzio01 -0.84 0.1417 94DAL82_SM htz1_del Mizuguch04 0.84 0.1417 55UME6_H2O2HiDrco1 Keogh05 -0.84 0.1417 94YAP6_YPD taf1-ts2_gcn5 Huisinga04 -0.84 0.1419 87CIN5_H2O2Lo ISW2 Hughes00 -0.84 0.1419 125STE12_BUT90 UBP8 Hughes00 0.84 0.1419 77GCR2_SM DT_N69R Chitikila_02 -0.84 0.142 52RCS1_H2O2Hi ubp10 Orlandi04 0.84 0.142 26AFT2_H2O2Lo elp3D Durant06 -0.84 0.142 81CIN5_YPD hat2_vs._YPH250Rosaleny05 -0.84 0.1421 143PUT3_H2O2Lo isw2_sin3_vs._sin3Fazzio01 -0.84 0.1421 86

SKN7_YPD snf2_minimal_medium_experimentSudarsanam00 -0.84 0.1422 67GLN3_RAPA ino80_+_0.1%_MMS_vs._ino80Attikum04 0.84 0.1422 57FKH2_H2O2Hi elp3D_taf1-ts2Durant06 0.84 0.1422 79RCS1_H2O2LoWT_V71R Chitikila_02 -0.84 0.1423 226ROX1_YPD gcn5 Huisinga04 0.84 0.1424 67UME6_YPD hht2K9131823GMartin04 0.84 0.1425 93MSN4_H2O2Hirpd3_H3dN_v_H3dNSabet04 0.84 0.1426 65UME6_H2O2HiEAF7 Krogan04 -0.84 0.1426 93DAL82_SM rpd3 Fazzio01 -0.84 0.1427 50MSN2_H2O2HiDT_N69S Chitikila_02 -0.84 0.1427 75REB1_H2O2Hi ISW2 Hughes00 0.84 0.1428 58ABF1_YPD SWC6_(VPS71)Krogan04 -0.84 0.1431 249RTG3_RAPA Set1_del Bernstein02 -0.84 0.1432 52UME6_H2O2Hihht2_K27G Martin04 0.84 0.1432 72XBP1_H2O2Lo SWC6_(VPS71)Krogan04 0.84 0.1432 59PHD1_YPD EAF7 Krogan04 -0.84 0.1433 60SWI4_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.84 0.1433 152UME6_H2O2Hiesa1-414_taf1-ts2Durant06 0.84 0.1433 97RCS1_H2O2Lotaf1-ts2_spt3_E240KHuisinga04 0.84 0.1433 243DAL82_RAPA ino80_del Mizuguch04 0.84 0.1434 56GLN3_RAPA isw2_c.i. Fazzio01 -0.84 0.1435 67CIN5_H2O2Lo WT_V161R_K Chitikila_02 -0.84 0.1435 119FKH2_YPD SIR1 Hughes00 -0.84 0.1435 119SWI5_YPD Drxt2 Keogh05 0.84 0.1437 98RIM101_H2O2Lotaf1-ts2_GCN5Huisinga04 -0.84 0.1437 47NRG1_YPD snf2_rich_medium_experimentSudarsanam00 0.84 0.1437 71REB1_YPD ume6 Fazzio01 0.84 0.1438 142GCR2_SM 0.1%_MMS Attikum04 -0.84 0.1438 47GCN4_YPD taf1-ts2_gcn5_KQLHuisinga04 0.84 0.1439 71TYE7_YPD DT_N69S Chitikila_02 0.84 0.144 50DIG1_BUT14 WT Durant06 0.84 0.144 59PHD1_BUT90 ISW2 Hughes00 -0.84 0.1443 106STE12_BUT90 Dpho23 Keogh05 0.84 0.1443 77GCN4_RAPA WT_WT Chitikila_02 -0.84 0.1444 157HSF1_H2O2Hi isw2_rpd3 Fazzio01 0.83 0.1448 118NDD1_YPD Hda1_del Bernstein02 0.83 0.1451 83NDD1_YPD WT_TAF1_GCN5Huisinga04 -0.83 0.1451 84STP1_SM set1 Boa03 -0.83 0.1452 67CIN5_H2O2Lo 0.1%_MMS Attikum04 0.83 0.1452 93SUM1_YPD hat1D Durant06 -0.83 0.1453 35MSN4_RAPA SWC6_(VPS71)Krogan04 0.83 0.1455 43MBP1_H2O2Lotaf1-ts2_25C Huisinga04 0.83 0.1455 52HSF1_H2O2Hi DT_V161R_K Chitikila_02 -0.83 0.1456 122MSN2_H2O2HiISW1_ISW2 Hughes00 0.83 0.1456 77OAF1_YPD WT_TAF1_GCN5Huisinga04 0.83 0.1457 57YAP6_H2O2Hi rpd3_H3dN_v_H3dNSabet04 0.83 0.146 71RIM101_H2O2LoWT_V161E Chitikila_02 -0.83 0.146 48ROX1_YPD sap30_del Bernstein_00_affydeletions-0.83 0.1461 52MSN4_RAPA Set1_del Bernstein02 -0.83 0.1464 54YAP1_YPD hht2_K914182327GMartin04 0.83 0.1465 62GCN4_RAPA hht2K9131823GMartin04 0.83 0.1465 137PHD1_BUT90 rsc30_null Angus-Hill_01 -0.83 0.1465 104ACE2_YPD snf2_minimal_medium_experimentSudarsanam00 -0.83 0.1465 80

MSN4_RAPA DT_N69S Chitikila_02 0.83 0.1466 44AFT2_H2O2Lo hat1_vs.YPH250Rosaleny05 0.83 0.1466 85CIN5_H2O2Hi hat1D_taf1-ts2Durant06 -0.83 0.1469 58STE12_BUT90 elp3D Durant06 -0.83 0.1469 67NRG1_YPD H3_1-28 Sabet04 0.83 0.1469 60PHO4_YPD MOT1-14 Dasgupta02 -0.83 0.147 71DAL82_SM SPT3 Ingvarsdottir05 -0.83 0.1471 45GLN3_RAPA BUR6 Geisberg_01 0.83 0.1472 62RCS1_H2O2Loesa1-414 Durant06 -0.83 0.1472 235ACE2_YPD WT_N69S Chitikila_02 -0.83 0.1472 70DAL81_RAPA spt3_E240K Huisinga04 -0.83 0.1473 85YAP7_H2O2Lo taf1-ts2_spt3 Huisinga04 0.83 0.1473 144RCS1_H2O2Hi rsc3-2 Angus-Hill_01 0.83 0.1474 50SKN7_H2O2Hi delta_ssd1 Kaeberlein04 0.83 0.1474 97RIM101_H2O2Lo0.1%_MMS Attikum04 -0.83 0.1474 32PUT3_H2O2Lo elp3D_taf1-ts2Durant06 0.83 0.1475 66OAF1_YPD isw2_rpd3 Fazzio01 0.83 0.1475 56YAP7_H2O2Hi SGF11 Ingvarsdottir05 0.83 0.1476 122GLN3_RAPA arp8_+_0.1%_MMS_vs._arp8Attikum04 0.83 0.1478 56MCM1_Alpha gcn5 Huisinga04 -0.83 0.1478 103SOK2_BUT14 delta_ssd1 Kaeberlein04 0.83 0.1478 72ROX1_YPD spt10 Eriksson05 0.83 0.1479 60MBP1_H2O2Hi elp3D Durant06 0.83 0.1479 107GLN3_RAPA EPL1 Mnaimneh_04 0.82 0.148 68HSF1_H2O2Losir4 Orlandi04 -0.82 0.148 75SWI6_YPD RSC8 Mnaimneh_04 0.82 0.1481 153STE12_BUT90 Hda1_del Bernstein02 0.82 0.1481 75ACE2_YPD EAF5 Krogan04 0.82 0.1482 71CIN5_H2O2Hi SIR2 Hughes00 0.82 0.1484 79ROX1_YPD DT_N69R Chitikila_02 -0.82 0.1485 66TYE7_YPD DT_V71E Chitikila_02 0.82 0.1485 54RCS1_H2O2Hi DM_vs._YPH250Rosaleny05 0.82 0.1485 47MCM1_Alpha hat1D Durant06 -0.82 0.1485 76MGA1_YPD UBP8 Ingvarsdottir05 -0.82 0.1486 58CIN5_YPD taf1-ts2_spt3 Huisinga04 -0.82 0.1487 141REB1_YPD DT_V71E Chitikila_02 0.82 0.1488 134NRG1_H2O2HiSAP30 Hughes00 0.82 0.1488 124NDD1_YPD hmr Meneghini03 -0.82 0.1488 83MBP1_H2O2LoTUP1_haploid Hughes00 -0.82 0.1489 57SUM1_YPD ume6_del Bernstein_00_affydeletions0.82 0.149 48DAL82_SM DT_V161E Chitikila_02 -0.82 0.149 51MBP1_H2O2Hi_SWC2_(VPS72)Krogan04 0.82 0.149 127YAP7_H2O2Lo Drpd3 Keogh05 0.82 0.1492 140FKH1_YPD WT_V161R_K Chitikila_02 -0.82 0.1492 124MBP1_YPD swi1_rich_medium_experimentSudarsanam00 -0.82 0.1492 130YAP7_H2O2Hi ubp10sir4 Orlandi04 -0.82 0.1493 104HAP4_YPD HST3 Hughes00 -0.82 0.1493 67CIN5_YPD HST3 Hughes00 0.82 0.1494 149MCM1_YPD hat1D Durant06 -0.82 0.1494 52YAP6_YPD ino80_del Mizuguch04 0.82 0.1498 90FKH2_YPD hat1_vs.YPH250Rosaleny05 0.82 0.1499 115SUM1_YPD hpa2D_taf1-ts2Durant06 -0.82 0.15 34SKN7_YPD spt10_del Xu05 -0.82 0.1501 65

STE12_BUT14 VID21 Krogan04 0.82 0.1501 116SWI4_YPD Dume1 Keogh05 -0.82 0.1502 141MBP1_H2O2LoSWD2 Mnaimneh_04 0.82 0.1502 58CIN5_H2O2Hi set1 Boa03 0.82 0.1503 80SWI6_YPD SSN6_haploid Hughes00 0.82 0.1504 152GLN3_RAPA 0.1%_MMS Attikum04 0.82 0.1504 55SKN7_H2O2HiSPT3 Ingvarsdottir05 -0.82 0.1504 82STE12_BUT90 H3_1-28 Sabet04 0.82 0.1504 74YAP7_H2O2Lo Drxt2 Keogh05 0.82 0.1505 140OAF1_YPD DT_V71E Chitikila_02 -0.82 0.1505 58ROX1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.82 0.1506 44YAP6_H2O2Hi WT_F182V Chitikila_02 -0.82 0.1506 63STE12_Alpha Dsin3 Keogh05 -0.82 0.1506 92GCN4_YPD delta_ssd1 Kaeberlein04 0.82 0.1507 75SWI6_YPD HIR2 Hughes00 -0.82 0.1509 151GCN4_YPD snf2_minimal_medium_experimentSudarsanam00 -0.82 0.1509 75CBF1_SM gcn5_KQL Huisinga04 0.82 0.151 247ASH1_BUT14 sin3 Fazzio01 0.82 0.151 49CBF1_SM rpd3_H4KQ_v_H4KQSabet04 -0.82 0.1511 272GCN4_SM MOT1-14 Dasgupta02 0.82 0.1512 188YAP6_H2O2Hi ume6 Fazzio01 -0.81 0.1514 73MCM1_Alpha hat2_vs._YPH250Rosaleny05 -0.81 0.1514 99UME6_YPD BUR6 Geisberg_01 0.81 0.1515 121YAP6_YPD spt10 Eriksson05 -0.81 0.1515 83DAL81_RAPA hos2_del Bernstein_00_affydeletions-0.81 0.1515 92ACE2_YPD Drpd3 Keogh05 0.81 0.1515 76SWI5_YPD hmr Meneghini03 -0.81 0.1516 100SWI6_YPD ino80_del Mizuguch04 -0.81 0.1516 153GLN3_RAPA SIR1 Hughes00 0.81 0.1516 68SWI5_YPD WT_N69S Chitikila_02 -0.81 0.1517 91UME6_YPD DT_V71R Chitikila_02 0.81 0.1517 117RTG3_RAPA TUP1_haploid Hughes00 0.81 0.1517 51SUT1_YPD isw2_sin3_vs._sin3Fazzio01 -0.81 0.152 69MSN2_H2O2HiHda1_del Bernstein02 0.81 0.1521 76HAP1_YPD Dpho23 Keogh05 -0.81 0.1521 140ABF1_YPD hda1_del Bernstein_00_affydeletions0.81 0.1522 255RLM1_YPD spt10 Eriksson05 -0.81 0.1522 53GCR2_SM Drpd3 Keogh05 0.81 0.1523 49MBP1_H2O2Lo0.1%_MMS Attikum04 0.81 0.1524 47HAP1_YPD taf1-ts2_spt3_E240KHuisinga04 0.81 0.1525 128MSN4_RAPA taf1-ts2 Durant06 0.81 0.1526 53STE12_YPD MOT1-42 Dasgupta02 0.81 0.1528 52PUT3_H2O2Lo DT_V161R_K Chitikila_02 0.81 0.1529 84SOK2_BUT14 WT_TAF1_GCN5Huisinga04 -0.81 0.1529 71FKH2_H2O2Hi IES6 Hughes00 0.81 0.153 105HSF1_H2O2Lo isw2_rpd3_vs._rpd3Fazzio01 0.81 0.153 97STE12_BUT14 SPT8 Ingvarsdottir05 -0.81 0.153 115ROX1_YPD WT_Null_K Chitikila_02 -0.81 0.1531 64ACE2_YPD 0.1%_MMS Attikum04 -0.81 0.1531 66ACE2_YPD Dpho23 Keogh05 0.81 0.1532 80SWI5_YPD Dpho23 Keogh05 0.81 0.1533 102TYE7_YPD snf2_rich_medium_experimentSudarsanam00 -0.81 0.1533 55PHD1_YPD ino80 Attikum04 0.81 0.1534 49

SKN7_H2O2HiMOT1-14 Dasgupta02 0.81 0.1534 98XBP1_H2O2Lo SWR1 Krogan04 -0.81 0.1534 63PHD1_BUT90 RAD6_haploid Hughes00 0.81 0.1534 106STE12_Alpha DT_V161E Chitikila_02 -0.81 0.1535 105SUM1_YPD YNG2 Mnaimneh_04 0.81 0.1536 59UME6_YPD Drco1 Keogh05 -0.81 0.1536 121AFT2_H2O2Lo WT_Null_L Chitikila_02 -0.81 0.1536 94PHD1_YPD ARD1 Hughes00 -0.81 0.1537 67NRG1_YPD SGF11 Ingvarsdottir05 0.81 0.1538 56DAL81_RAPA delta_ssd1 Kaeberlein04 0.81 0.154 95SUT1_YPD SPT8 Ingvarsdottir05 -0.81 0.1544 61UME6_YPD htz1_del Mizuguch04 0.81 0.1544 131GCN4_YPD rsc30_null Angus-Hill_01 -0.81 0.1544 71SUT1_YPD DT_Null Chitikila_02 0.81 0.1545 67DAL82_RAPA taf1-ts2_spt3 Huisinga04 0.81 0.1545 53YAP7_H2O2Hi Drxt2 Keogh05 0.81 0.1545 131XBP1_H2O2Lo spt10 Eriksson05 0.81 0.1545 61STE12_BUT90 hpa2D Durant06 -0.81 0.1545 64CBF1_SM hpa2D_taf1-ts2Durant06 0.81 0.1547 219REB1_YPD htz1_hmr Meneghini03 0.81 0.1548 137RLM1_YPD DT_V161R_L Chitikila_02 -0.81 0.1548 49RLM1_YPD Drco1 Keogh05 0.81 0.1548 51AFT2_H2O2Hi WT_Null_L Chitikila_02 -0.8 0.155 57AFT2_H2O2Lo gcn5D Durant06 0.8 0.1551 76CIN5_H2O2Hi sas3D_taf1-ts2Durant06 0.8 0.1552 63SWI4_YPD isw2_ume6 Fazzio01 -0.8 0.1553 152SKN7_H2O2Hi isw2_c.i. Fazzio01 -0.8 0.1554 95PHO4_YPD taf1-ts2_25C Huisinga04 0.8 0.1555 68DAL81_RAPA ume6_del Bernstein_00_affydeletions0.8 0.1555 93CIN5_H2O2Lo WT_TAF1_GCN5Huisinga04 -0.8 0.1555 126STE12_BUT14 SIR3 Hughes00 -0.8 0.1556 126STE12_BUT14 WT_V161R_K Chitikila_02 -0.8 0.1556 115MCM1_YPD SWD2 Mnaimneh_04 0.8 0.1556 77ROX1_YPD EAF7 Krogan04 0.8 0.1557 62DIG1_BUT14 H4KQ Sabet04 -0.8 0.1557 63HSF1_H2O2LoSGF11 Ingvarsdottir05 0.8 0.1558 84GCN4_SM SSD1-V Kaeberlein04 0.8 0.1559 189MCM1_Alpha hda1_del Bernstein_00_affydeletions-0.8 0.1559 99RLM1_YPD Dsds3 Keogh05 -0.8 0.1562 51TYE7_YPD WT_TAF1_GCN5Huisinga04 0.8 0.1562 55YAP6_YPD ARP4 Mnaimneh_04 0.8 0.1562 91MGA1_YPD WT_N69R Chitikila_02 0.8 0.1562 57GCN4_YPD DT_WT Chitikila_02 -0.8 0.1563 75SWI5_YPD RPD3_haploid Hughes00 0.8 0.1564 97DAL82_SM htz1_sir2 Meneghini03 0.8 0.1564 54CIN5_H2O2Hi HST3 Hughes00 0.8 0.1564 79RPN4_H2O2Lorsc3-2 Angus-Hill_01 -0.8 0.1564 99SKN7_H2O2LoDsin3 Keogh05 0.8 0.1564 148REB1_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 0.8 0.1565 57MCM1_Alpha delta_ssd1 Kaeberlein04 0.8 0.1565 106DIG1_BUT14 YNG2 Krogan04 0.8 0.1565 61YAP7_H2O2Lo SPT8 Ingvarsdottir05 0.8 0.1567 137DIG1_Alpha UBP8 Ingvarsdottir05 0.8 0.1567 56

MGA1_YPD rpd3_del Sabet04 -0.8 0.1567 61ABF1_YPD sir4 Orlandi04 -0.8 0.157 221MBP1_YPD taf1-ts2_GCN5Huisinga04 0.8 0.157 117MSN4_H2O2HiSIR4 Hughes00 -0.8 0.1571 68FKH1_YPD snf2_minimal_medium_experimentSudarsanam00 -0.8 0.1571 142STE12_BUT90 isw2 Fazzio01 0.8 0.1571 77ASH1_BUT14 ISW1_ISW2 Hughes00 0.8 0.1573 50SKN7_H2O2LoDdep1 Keogh05 0.8 0.1574 176STE12_BUT14 Drpd3 Keogh05 -0.8 0.1574 116STP1_SM htz1_hmr Meneghini03 0.8 0.1575 65DIG1_BUT14 snf2_minimal_medium_experimentSudarsanam00 -0.8 0.1575 63PHD1_BUT90 ubp10sir4 Orlandi04 -0.8 0.1575 62SWI4_YPD elp3D Durant06 0.8 0.1577 129REB1_H2O2Hi WT_V161R_L Chitikila_02 0.8 0.1577 57MBP1_H2O2LoRpd3_del Bernstein02 0.8 0.1578 57ACE2_YPD spt3_E240K Huisinga04 -0.8 0.1578 69SWI6_YPD SGF11 Ingvarsdottir05 -0.8 0.1579 125REB1_H2O2Hi WT_N69S Chitikila_02 0.8 0.1579 53HAP4_YPD MOT1-42 Dasgupta02 -0.8 0.1579 67RLM1_YPD SIR2 Hughes00 -0.8 0.158 55RCS1_H2O2Hi SIR2 Hughes00 -0.8 0.158 52GCN4_YPD DT_Null Chitikila_02 -0.8 0.158 75HAP4_YPD hpa2D Durant06 -0.8 0.1581 55HAP4_YPD BUR6 Geisberg_01 0.8 0.1581 60HAP4_YPD snf2_rich_medium_experimentSudarsanam00 -0.8 0.1582 67MBP1_YPD WT_TAF1_SPT3Huisinga04 -0.8 0.1582 126MGA1_YPD SSD1-V Kaeberlein04 -0.8 0.1582 62DAL82_SM elp3D_taf1-ts2Durant06 0.8 0.1584 42SWI6_YPD hda1_del Bernstein_00_affydeletions0.79 0.1585 144YAP1_YPD taf1-ts2_gcn5 Huisinga04 0.79 0.1585 69FKH2_YPD rpd3_H4KQ_v_H4KQSabet04 -0.79 0.1585 118YAP1_YPD elp3D_taf1-ts2Durant06 0.79 0.1586 58YAP6_YPD RAD6_haploid Hughes00 0.79 0.1586 91AFT2_H2O2Hi WT_V161R_K Chitikila_02 -0.79 0.1586 56STE12_BUT14 sin3 Fazzio01 -0.79 0.1586 127PHO4_YPD ubp10 Orlandi04 0.79 0.1587 45STE12_BUT14 WT_N69R Chitikila_02 -0.79 0.1588 116MBP1_H2O2LoMOT1-14 Dasgupta02 -0.79 0.1589 57RPN4_H2O2LoYAF9 Krogan04 0.79 0.1589 99YAP6_H2O2Lo snf2_minimal_medium_experimentSudarsanam00 0.79 0.1589 58REB1_YPD Drpd3 Keogh05 -0.79 0.159 130STE12_YPD taf1-ts2_gcn5 Huisinga04 0.79 0.159 49YAP1_YPD ARP4 Mnaimneh_04 0.79 0.159 72MBP1_H2O2Hihat1D_taf1-ts2Durant06 0.79 0.159 109MSN4_H2O2HiSGF11 Ingvarsdottir05 0.79 0.159 63RCS1_H2O2Loswi1_rich_medium_experimentSudarsanam00 0.79 0.1591 257UME6_YPD SSD1-V Kaeberlein04 0.79 0.1592 131DAL82_SM Drxt2 Keogh05 -0.79 0.1592 50CBF1_SM RPD3_haploid Hughes00 0.79 0.1594 273YAP7_H2O2Hi isw2_c.i. Fazzio01 -0.79 0.1594 137CBF1_SM swr1_del Mizuguch04 0.79 0.1595 279RIM101_H2O2LoSGF11 Ingvarsdottir05 0.79 0.1595 47CIN5_H2O2Hi rsc30_null Angus-Hill_01 -0.79 0.1596 78

YAP6_YPD MOT1-42 Dasgupta02 0.79 0.1597 91RLM1_YPD rsc3-2 Angus-Hill_01 -0.79 0.1598 53SWI5_YPD IOC4 Hughes00 -0.79 0.1598 100AFT2_H2O2Hi swr1_del Mizuguch04 0.79 0.1598 61REB1_YPD DT_Null Chitikila_02 0.79 0.16 130GCN4_SM EPL1 Mnaimneh_04 0.79 0.16 189HSF1_H2O2Hi Set1_del Bernstein02 0.79 0.16 122UME6_H2O2Hihat1D_taf1-ts2Durant06 0.79 0.16 82DIG1_Alpha SAP30 Hughes00 0.79 0.16 59SOK2_BUT14 EPL1 Mnaimneh_04 0.79 0.16 72ROX1_YPD Dsap30 Keogh05 -0.79 0.1601 66MCM1_Alpha YNG2 Krogan04 0.79 0.1602 103CIN5_H2O2Hi ARD1 Hughes00 -0.79 0.1603 79UME6_H2O2HiUBP8 Ingvarsdottir05 0.79 0.1604 91SKN7_H2O2Loarp8 Attikum04 0.79 0.1604 144MBP1_H2O2LoSPT8 Ingvarsdottir05 0.79 0.1605 52RIM101_H2O2Lohht2_K4914182327GMartin04 0.79 0.1605 29SOK2_BUT14 SGF11 Ingvarsdottir05 -0.79 0.1605 59GCN4_YPD EAF7 Krogan04 0.79 0.1605 67RLM1_YPD TUP1_haploid Hughes00 0.79 0.1606 53AFT2_H2O2Lo YAF9 Krogan04 0.79 0.1606 89SOK2_BUT14 MOT1-42 Dasgupta02 0.79 0.1606 72PHD1_YPD hat2_vs._YPH250Rosaleny05 0.79 0.1607 62YAP7_H2O2Hi swi1_rich_medium_experimentSudarsanam00 0.79 0.1607 140STP1_SM HTZ1 Krogan04 0.79 0.1608 64RTG3_RAPA WT_N69R Chitikila_02 -0.79 0.1608 48RPN4_H2O2LoBUR6 Geisberg_01 0.79 0.1609 98UME6_YPD SIR3 Hughes00 0.79 0.161 127CIN5_YPD WT Durant06 -0.79 0.161 141DIG1_Alpha sin3_del Bernstein_00_affydeletions-0.79 0.161 53MCM1_Alpha hat1D_taf1-ts2Durant06 0.79 0.161 82PUT3_H2O2Lo WT_Null_K Chitikila_02 -0.79 0.1611 83HAP4_YPD ubp10sir4 Orlandi04 0.79 0.1611 46NDD1_YPD Drco1 Keogh05 0.79 0.1611 80YAP6_H2O2Hi DT_V71R Chitikila_02 0.79 0.1613 74DIG1_BUT14 SAP30 Hughes00 0.79 0.1613 62CBF1_SM taf1-ts2_gcn5_KQLHuisinga04 0.79 0.1614 247MSN2_H2O2Hielp3D Durant06 -0.79 0.1615 68SKN7_H2O2LoDpho23 Keogh05 0.79 0.1615 183ASH1_BUT14 swi1_minimal_medium_experimentSudarsanam00 0.79 0.1616 50CIN5_H2O2Hi hos2_del Bernstein_00_affydeletions-0.79 0.1617 68STE12_BUT90 DT_WT Chitikila_02 -0.79 0.1617 74STE12_BUT90 DT_V71R Chitikila_02 -0.79 0.1618 72GCR2_SM EPL1 Mnaimneh_04 0.79 0.1619 54OAF1_YPD hda1_del Bernstein_00_affydeletions-0.79 0.162 52CIN5_H2O2Hi hat1_vs.YPH250Rosaleny05 0.79 0.1621 76NRG1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.79 0.1621 35SUT1_YPD hht2_K4914182327GMartin04 -0.78 0.1623 49DAL81_RAPA UBP8 Ingvarsdottir05 -0.78 0.1623 84MSN4_RAPA RPD3_haploid Hughes00 -0.78 0.1623 54ASH1_BUT14 HST3 Hughes00 -0.78 0.1623 50NRG1_H2O2HiH3_1-28 Sabet04 0.78 0.1624 120STE12_BUT90 rpd3_c.i. Fazzio01 -0.78 0.1624 77

MSN4_RAPA taf1-ts2_gcn5_KQLHuisinga04 0.78 0.1626 49CIN5_H2O2Lo taf1-ts2_gcn5 Huisinga04 0.78 0.1626 120RCS1_H2O2Losin3 Fazzio01 0.78 0.1626 253FKH2_H2O2Hi TUP1_haploid Hughes00 -0.78 0.1628 105NRG1_YPD hht2_K4G Martin04 -0.78 0.1628 35ROX1_YPD isw2_ume6 Fazzio01 0.78 0.1629 67MCM1_Alpha hos3_del Bernstein_00_affydeletions-0.78 0.1629 100HAP1_YPD SIR3 Hughes00 0.78 0.1629 141GLN3_RAPA gcn5D Durant06 -0.78 0.163 58RLM1_YPD snf2_minimal_medium_experimentSudarsanam00 -0.78 0.1632 54YAP1_YPD WT_V161R_K Chitikila_02 -0.78 0.1633 68CBF1_SM hht2_K27G Martin04 0.78 0.1633 226STE12_Alpha hat1D Durant06 -0.78 0.1635 84GCN4_YPD TAF2 Mnaimneh_04 -0.78 0.1636 75SWI5_YPD hht2_K4G Martin04 0.78 0.1638 81MGA1_YPD SPT8 Ingvarsdottir05 0.78 0.1638 58MBP1_YPD Drpd3 Keogh05 0.78 0.164 122HSF1_H2O2Lo isw2_ume6 Fazzio01 0.78 0.1641 97SUM1_YPD ubp10sir4 Orlandi04 0.78 0.1642 21YAP6_H2O2Hi hat2_vs._YPH250Rosaleny05 0.78 0.1642 69AFT2_H2O2Lo isw2_sin3 Fazzio01 -0.78 0.1642 95STE12_Alpha IES6 Hughes00 0.78 0.1642 114NRG1_YPD taf1-ts2_25C Huisinga04 -0.78 0.1642 65NRG1_H2O2Hihht2_K4G Martin04 -0.78 0.1643 83GCR2_SM SSN6_haploid Hughes00 0.78 0.1645 53MBP1_YPD _SWC2_(VPS72)Krogan04 0.78 0.1645 124NRG1_H2O2HiSPT3 Ingvarsdottir05 0.78 0.1646 109YAP1_YPD swr1_del Mizuguch04 0.78 0.1649 72GCR2_SM arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.78 0.1649 45SKN7_H2O2Loisw2 Fazzio01 0.78 0.1649 181FKH2_YPD HIR2 Hughes00 -0.78 0.1649 117MCM1_Alpha WT_N69S Chitikila_02 0.78 0.165 93SOK2_BUT14 DT_V71E Chitikila_02 -0.78 0.165 70FKH1_YPD SWC6_(VPS71)Krogan04 0.78 0.1651 134PUT3_H2O2Lo UBP8 Hughes00 0.78 0.1652 86DIG1_Alpha isw2_rpd3_vs._rpd3Fazzio01 0.78 0.1652 59HSF1_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 -0.78 0.1653 124REB1_H2O2Hi TUP1_haploid Hughes00 -0.78 0.1653 58GCN4_YPD SSN6_haploid Hughes00 -0.78 0.1653 74GCN4_SM DT_Null Chitikila_02 -0.78 0.1654 182GCR2_SM isw2_rpd3 Fazzio01 -0.78 0.1654 52MSN2_H2O2HiARD1 Hughes00 0.78 0.1654 77ROX1_YPD ume6_del Bernstein_00_affydeletions0.78 0.1655 55YAP6_YPD IES6 Hughes00 -0.78 0.1655 91YAP6_YPD DT_V71R Chitikila_02 0.78 0.1655 85YAP6_H2O2Hi ino80 Attikum04 -0.78 0.1659 48SWI5_YPD EAF7 Krogan04 0.77 0.166 94HAP1_YPD hht2_K4914182327GMartin04 -0.77 0.166 122REB1_H2O2Hi Set1_del Bernstein02 -0.77 0.1661 57MCM1_Alpha spt10 Eriksson05 -0.77 0.1661 103MBP1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.77 0.1661 113PHD1_YPD isw2_sin3_vs._sin3Fazzio01 0.77 0.1663 66MSN4_RAPA hos3_del Bernstein_00_affydeletions-0.77 0.1663 50

RCS1_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 -0.77 0.1663 50DIG1_Alpha isw2 Fazzio01 -0.77 0.1663 59MSN4_RAPA hos2_del Bernstein_00_affydeletions-0.77 0.1664 50ROX1_YPD hht2K9131823GMartin04 0.77 0.1665 41CBF1_SM SWD2 Mnaimneh_04 0.77 0.1665 277STP1_SM Rpd3_del Bernstein02 -0.77 0.1665 67SWI4_YPD sas3D Durant06 -0.77 0.1666 128STE12_BUT90 WT_V161E Chitikila_02 -0.77 0.1666 71RIM101_H2O2LoDT_V161E Chitikila_02 -0.77 0.1668 49RPN4_H2O2LoSIR2 Hughes00 0.77 0.1668 99STE12_BUT14 H4KQ Sabet04 -0.77 0.1668 122MCM1_YPD sap30_del Bernstein_00_affydeletions-0.77 0.1669 68ABF1_YPD ino80_del Mizuguch04 -0.77 0.167 266ASH1_BUT14 isw2_sin3_vs._sin3Fazzio01 -0.77 0.167 49MSN2_H2O2HiDsap30 Keogh05 0.77 0.1671 72GCN4_SM EAF5 Krogan04 -0.77 0.1672 169CIN5_H2O2Hi WT_N69S Chitikila_02 0.77 0.1674 76XBP1_H2O2Lo ino80_del Mizuguch04 0.77 0.1674 67STE12_BUT14 isw2_rpd3 Fazzio01 -0.77 0.1674 126YAP7_H2O2Hi WT_V161R_K Chitikila_02 -0.77 0.1675 130CIN5_H2O2Lo hat1D_taf1-ts2Durant06 0.77 0.1675 104ASH1_BUT14 rsc30_null Angus-Hill_01 -0.77 0.1675 49AFT2_H2O2Hi IOC4 Hughes00 0.77 0.1676 61SKN7_YPD HTZ1 Krogan04 0.77 0.1677 61RPN4_H2O2Loisw2_rpd3_vs._rpd3Fazzio01 0.77 0.1678 97NDD1_YPD swr1_del Mizuguch04 0.77 0.1678 84AFT2_H2O2Lo HAT2 Hughes00 0.77 0.168 98HAP4_YPD MOT1-14 Dasgupta02 0.77 0.168 64REB1_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 0.77 0.1681 57ROX1_YPD hat2_vs._hat1Rosaleny05 0.77 0.1682 63SUM1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.77 0.1682 31FKH1_YPD gcn5_KQL Huisinga04 -0.77 0.1683 123SKN7_YPD ume6 Fazzio01 -0.77 0.1686 63RLM1_YPD WT_V71R Chitikila_02 -0.77 0.1687 50ROX1_YPD SIR3 Hughes00 0.77 0.1687 67MBP1_YPD WT_F182V Chitikila_02 0.77 0.1687 106GCR2_SM EAF5 Krogan04 0.77 0.1688 49RTG3_RAPA SIR3 Hughes00 0.77 0.1689 52RCS1_H2O2Hi MOT1-42 Dasgupta02 -0.77 0.1692 52ACE2_YPD SSN6_haploid Hughes00 0.77 0.1692 80DAL82_SM esa1-414 Durant06 0.77 0.1693 51PHD1_YPD WT_N69R Chitikila_02 -0.77 0.1694 58UME6_YPD hat1D Durant06 -0.77 0.1694 96UME6_YPD htz1 Meneghini03 0.77 0.1694 125UME6_YPD Set1_del Bernstein02 0.77 0.1694 129PUT3_H2O2Lo taf1-ts2 Durant06 0.77 0.1694 86MSN4_RAPA taf1-ts2_GCN5Huisinga04 0.77 0.1695 51SWI5_YPD swr1_del Mizuguch04 0.77 0.1696 102DIG1_Alpha Dume1 Keogh05 -0.77 0.1696 57ACE2_YPD ume6_del Bernstein_00_affydeletions0.77 0.1696 74DAL82_SM sas3D_taf1-ts2Durant06 0.77 0.1697 48AFT2_H2O2Lo Dsap30 Keogh05 0.77 0.1697 93MCM1_YPD H3KQ Sabet04 -0.77 0.1697 73

NDD1_YPD ubp10 Orlandi04 0.77 0.1697 67DIG1_BUT14 taf1-ts2_spt3 Huisinga04 -0.76 0.1699 62HAP1_YPD hht2_K914182327GMartin04 0.76 0.1699 118MGA1_YPD SSN6_haploid Hughes00 -0.76 0.1699 61CBF1_SM WT_TAF1_GCN5Huisinga04 0.76 0.17 276MSN4_RAPA snf2_rich_medium_experimentSudarsanam00 0.76 0.17 54MBP1_H2O2HiTUP1_haploid Hughes00 -0.76 0.1701 132SWI5_YPD Drxt1 Keogh05 -0.76 0.1702 101RCS1_H2O2LoVID21 Krogan04 0.76 0.1702 242ASH1_BUT14 SWR1 Krogan04 0.76 0.1702 48RLM1_YPD hht2_K4914182327GMartin04 0.76 0.1703 42RIM101_H2O2LoHST3 Hughes00 0.76 0.1703 53RIM101_H2O2LoWT_N69S Chitikila_02 0.76 0.1706 45HSF1_H2O2LoISW1 Hughes00 0.76 0.1709 99PHD1_YPD gcn5D_taf1-ts2Durant06 0.76 0.171 58STE12_YPD HIR2 Hughes00 0.76 0.171 54CIN5_YPD delta_ssd1 Kaeberlein04 0.76 0.171 150ASH1_BUT14 SPT8 Ingvarsdottir05 -0.76 0.171 42PHD1_YPD WT_V71R Chitikila_02 0.76 0.1711 63NDD1_YPD VID21 Krogan04 0.76 0.1711 75MGA1_YPD swr1_del Mizuguch04 0.76 0.1712 62RLM1_YPD taf1-ts2_SPT3 Huisinga04 0.76 0.1713 50DIG1_BUT14 SGF11 Ingvarsdottir05 -0.76 0.1713 53PHD1_YPD ISW2 Hughes00 0.76 0.1715 67SKN7_YPD RAD6_haploid Hughes00 0.76 0.1715 66AFT2_H2O2Hi MED2_haploid Hughes00 0.76 0.1715 61PUT3_H2O2Lo DT_V71E Chitikila_02 0.76 0.1717 85YAP6_H2O2Lo VID21 Krogan04 0.76 0.1717 53PHO4_YPD taf1-ts2_gcn5_KQLHuisinga04 -0.76 0.1718 67NRG1_H2O2Hisas3D Durant06 0.76 0.1718 93PUT3_H2O2Lo WT_V161R_K Chitikila_02 0.76 0.1718 79RLM1_YPD hat1_vs.YPH250Rosaleny05 -0.76 0.1719 53REB1_YPD VID21 Krogan04 0.76 0.172 133HSF1_H2O2LoDpho23 Keogh05 0.76 0.172 100GCN4_YPD SWR1 Krogan04 0.76 0.172 65REB1_H2O2Hi Dume1 Keogh05 0.76 0.1721 56DIG1_Alpha Drco1 Keogh05 -0.76 0.1724 60FKH2_YPD htz1_sir2 Meneghini03 0.76 0.1725 119ROX1_YPD taf1-ts2_gcn5_KQLHuisinga04 -0.76 0.1726 58SWI5_YPD WT_TAF1_SPT3Huisinga04 0.76 0.1727 94CIN5_YPD spt10_del Xu05 -0.76 0.1728 149YAP6_YPD WT_V161R_L Chitikila_02 -0.76 0.1729 88HAP1_YPD spt10_del Xu05 0.76 0.1729 140SWI5_YPD isw2_c.i. Fazzio01 -0.76 0.173 94DAL82_SM gcn5D Durant06 -0.76 0.1732 44STP1_SM H3_1-28 Sabet04 -0.76 0.1732 67MSN4_RAPA rsc30_null Angus-Hill_01 0.76 0.1732 53SOK2_BUT14 TAF2 Mnaimneh_04 0.76 0.1732 72FKH2_YPD hht2_K914182327GMartin04 0.76 0.1734 101AFT2_H2O2Hi spt10_del Xu05 0.76 0.1735 61SOK2_BUT14 spt10_del Xu05 -0.76 0.1735 72HAP1_YPD isw2_rpd3 Fazzio01 -0.76 0.1735 136PHO4_YPD hda1_del Bernstein_00_affydeletions-0.76 0.1736 68

SWI6_YPD ume6 Fazzio01 -0.76 0.1736 148STP1_SM taf1-ts2_gcn5_KQLHuisinga04 0.76 0.1737 64YAP7_H2O2Lo ARP4 Mnaimneh_04 0.75 0.1738 152STE12_BUT90 DT_V161E Chitikila_02 -0.75 0.1738 72STE12_BUT90 SWR1 Krogan04 0.75 0.1739 75RLM1_YPD hht2_K49141823GMartin04 -0.75 0.174 42DAL82_RAPA ISW1 Hughes00 0.75 0.174 56STE12_Alpha ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.75 0.174 86FKH1_YPD SIR3 Hughes00 -0.75 0.1741 141SWI4_YPD rpd3 Fazzio01 0.75 0.1743 152RIM101_H2O2Lohos3_del Bernstein_00_affydeletions-0.75 0.1743 39FKH2_H2O2Hi DT_WT Chitikila_02 -0.75 0.1744 100HSF1_H2O2Hi isw2_c.i. Fazzio01 0.75 0.1744 119PHO4_YPD DT_Null Chitikila_02 -0.75 0.1746 67YAP6_H2O2Lo SWR1 Krogan04 -0.75 0.1746 52GCN4_SM hos2_del Bernstein_00_affydeletions-0.75 0.1747 183CIN5_H2O2Hi hht2_K914182327GMartin04 0.75 0.1747 50MCM1_YPD WT_V71R Chitikila_02 0.75 0.1749 67NDD1_YPD hht2K9131823GMartin04 0.75 0.1749 75YAP1_YPD arp8 Attikum04 -0.75 0.175 58YAP1_YPD hda1_del Bernstein_00_affydeletions0.75 0.1751 67MGA1_YPD SIR2 Hughes00 -0.75 0.1752 62RCS1_H2O2LoEAF7 Krogan04 0.75 0.1753 237YAP1_YPD VID21 Krogan04 -0.75 0.1754 66MCM1_Alpha rpd3_H4KQ_v_H4KQSabet04 -0.75 0.1755 102STE12_Alpha gcn5D_taf1-ts2Durant06 0.75 0.1756 99MSN2_H2O2Hisas3D Durant06 0.75 0.1757 63CIN5_H2O2Lo Dpho23 Keogh05 -0.75 0.1757 125SOK2_BUT14 SPT3 Ingvarsdottir05 -0.75 0.1757 66HAP1_YPD gcn5D Durant06 0.75 0.1757 122AFT2_H2O2Lo DT_V71R Chitikila_02 0.75 0.1758 96RPN4_H2O2LoSWC6_(VPS71)Krogan04 -0.75 0.1758 95MBP1_H2O2LoSGF11 Ingvarsdottir05 0.75 0.1759 48OAF1_YPD rpd3_H3dN_v_H3dNSabet04 0.75 0.176 55SUT1_YPD rsc30_null Angus-Hill_01 -0.75 0.1761 69SWI4_YPD taf1-ts2_SPT3 Huisinga04 0.75 0.1761 149MCM1_Alpha snf2_minimal_medium_experimentSudarsanam00 -0.75 0.1761 106ASH1_BUT14 SIR3 Hughes00 -0.75 0.1763 50SUM1_YPD sas3D_taf1-ts2Durant06 -0.75 0.1764 47UME6_H2O2HiWT_V161R_L Chitikila_02 0.75 0.1764 91PHD1_BUT90 Drpd3 Keogh05 0.75 0.1764 96MSN2_H2O2Hiisw2_ume6 Fazzio01 -0.75 0.1766 75PHD1_YPD IOC4 Hughes00 -0.75 0.1767 66STE12_YPD EPL1 Mnaimneh_04 0.75 0.1767 54YAP7_H2O2Lo spt3_E240K Huisinga04 0.75 0.1768 132ASH1_BUT14 rpd3_H4KQ_v_H4KQSabet04 -0.75 0.1768 47GLN3_RAPA hos2_del Bernstein_00_affydeletions-0.75 0.1769 63GCN4_SM WT_F182V Chitikila_02 0.75 0.177 148HSF1_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 0.75 0.177 119HSF1_H2O2Loswi1_rich_medium_experimentSudarsanam00 0.75 0.1771 101FKH2_H2O2Hi isw2 Fazzio01 0.75 0.1772 104YAP6_H2O2Hi RAD6_haploid Hughes00 0.75 0.1772 77AFT2_H2O2Hi WT_V71R Chitikila_02 -0.75 0.1773 54

AFT2_H2O2Lo H3KQ Sabet04 0.75 0.1773 92MBP1_H2O2HiH3_1-28 Sabet04 -0.75 0.1774 129AFT2_H2O2Lo Drpd3 Keogh05 0.75 0.1776 87FKH1_YPD hht2_K49141823GMartin04 0.75 0.1776 121DAL82_SM Dpho23 Keogh05 -0.75 0.1777 53SKN7_H2O2Hi gcn5D Durant06 0.75 0.1778 83RCS1_H2O2Losnf2_minimal_medium_experimentSudarsanam00 0.74 0.1779 257AFT2_H2O2Hi isw2_sin3_vs._sin3Fazzio01 0.74 0.178 58SKN7_H2O2LoDT_WT Chitikila_02 -0.74 0.1781 175YAP7_H2O2Lo ISW1_ISW2 Hughes00 -0.74 0.1781 152XBP1_H2O2Lo isw2_sin3_vs._sin3Fazzio01 -0.74 0.1782 65XBP1_H2O2Lo hmr Meneghini03 -0.74 0.1782 67ASH1_BUT14 WT_TAF1_SPT3Huisinga04 0.74 0.1782 47HAP1_YPD MED2_haploid Hughes00 -0.74 0.1782 140GCN4_RAPA H3_1-28 Sabet04 0.74 0.1784 156GLN3_RAPA WT Durant06 -0.74 0.1784 65STE12_BUT90 Ddep1 Keogh05 0.74 0.1784 73REB1_YPD HST3 Hughes00 -0.74 0.1785 140CIN5_YPD ume6_del Bernstein_00_affydeletions0.74 0.1785 137NRG1_H2O2Hirpd3_del Sabet04 -0.74 0.1785 120CIN5_H2O2Hi YNG2 Krogan04 -0.74 0.1786 74DAL82_RAPA sin3_del Bernstein_00_affydeletions-0.74 0.1787 50YAP6_H2O2Hi PCH1 Hughes00 -0.74 0.1787 77PHD1_BUT90 SIR4 Hughes00 0.74 0.1787 106HAP1_YPD Dsds3 Keogh05 0.74 0.1787 128TYE7_YPD WT_V161E Chitikila_02 0.74 0.1788 53STE12_Alpha hht2_K914182327GMartin04 -0.74 0.1788 91SWI4_YPD arp8 Attikum04 -0.74 0.179 117DAL82_SM Set1_del Bernstein02 0.74 0.179 54XBP1_H2O2Lo Dsin3 Keogh05 0.74 0.1792 60STE12_Alpha ISW1_ISW2 Hughes00 -0.74 0.1792 115OAF1_YPD UBP8 Hughes00 0.74 0.1794 59CIN5_H2O2Lo taf1-ts2 Durant06 0.74 0.1797 127PHD1_BUT90 IOC4 Hughes00 -0.74 0.1797 106ASH1_BUT14 gcn5D Durant06 0.74 0.1798 41GLN3_RAPA htz1 Meneghini03 -0.74 0.1799 64CBF1_SM TUP1_haploid Hughes00 0.74 0.18 273MSN4_H2O2HiDrco1 Keogh05 0.74 0.18 64YAP6_H2O2Hi ubp10 Orlandi04 0.74 0.18 37CIN5_YPD H4_2-26 Sabet04 0.74 0.1801 144ROX1_YPD elp3D Durant06 0.74 0.1802 53SWI4_YPD rpd3_del Sabet04 -0.74 0.1802 151REB1_H2O2Hi isw2_sin3_vs._sin3Fazzio01 0.74 0.1802 57RCS1_H2O2LoWT_TAF1_GCN5Huisinga04 0.74 0.1802 252YAP6_YPD PCH1 Hughes00 0.74 0.1805 91OAF1_YPD delta_ssd1 Kaeberlein04 0.74 0.1806 59DAL81_RAPA set1 Boa03 0.74 0.1807 92MCM1_YPD WT_TAF1_GCN5Huisinga04 -0.74 0.1807 77CIN5_H2O2Hi sir4 Orlandi04 -0.74 0.1808 42YAP6_H2O2Hi Dpho23 Keogh05 -0.74 0.1808 78STE12_BUT90 isw2_c.i._rpd3_c.i.Fazzio01 -0.74 0.1808 77FKH2_H2O2Hi ubp10sir4 Orlandi04 -0.74 0.1811 79UME6_H2O2Hidelta_ssd1 Kaeberlein04 -0.74 0.1811 102

SOK2_BUT14 hht2_K914182327GMartin04 0.74 0.1812 46GLN3_RAPA hht2_K27G Martin04 -0.74 0.1813 50MBP1_YPD ino80_del Mizuguch04 -0.74 0.1813 129YAP6_H2O2Hi sin3_del Bernstein_00_affydeletions-0.74 0.1814 69PHD1_BUT90 HST3 Hughes00 0.74 0.1817 106NDD1_YPD ZDS1 Hughes00 0.74 0.1818 84SKN7_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.74 0.1819 76SKN7_H2O2HiSWD2 Mnaimneh_04 -0.74 0.1819 98AFT2_H2O2Hi hos2_del Bernstein_00_affydeletions-0.73 0.1821 52FKH2_H2O2Hi ume6_del Bernstein_00_affydeletions-0.73 0.1822 102RLM1_YPD DT_N69R Chitikila_02 -0.73 0.1823 50STP1_SM WT_N69R Chitikila_02 -0.73 0.1823 60RTG3_RAPA set1 Boa03 -0.73 0.1824 51GCR2_SM SIR1 Hughes00 0.73 0.1825 52UME6_H2O2HiSWD2 Mnaimneh_04 0.73 0.1825 102HSF1_H2O2Hi PCH1 Hughes00 0.73 0.1826 121HSF1_H2O2Hi hda1_del Bernstein_00_affydeletions0.73 0.1827 118MGA1_YPD WT_WT Chitikila_02 0.73 0.1827 56REB1_YPD Dsin3 Keogh05 -0.73 0.1829 125ROX1_YPD H4KQ Sabet04 0.73 0.1829 58SUM1_YPD hat1D_taf1-ts2Durant06 -0.73 0.183 35STP1_SM SAP30 Hughes00 0.73 0.183 67MCM1_Alpha Rpd3_del Bernstein02 0.73 0.1832 106FKH1_YPD htz1_hmr Meneghini03 0.73 0.1832 140SWI6_YPD set1 Boa03 -0.73 0.1833 150RLM1_YPD hos2_del Bernstein_00_affydeletions0.73 0.1834 46UME6_H2O2HiSSN6_haploid Hughes00 0.73 0.1834 97RLM1_YPD DT_WT Chitikila_02 -0.73 0.1837 51GCR2_SM isw2_rpd3_vs._rpd3Fazzio01 -0.73 0.1837 52REB1_H2O2Hi WT_WT Chitikila_02 -0.73 0.1838 57ABF1_YPD SIR2 Hughes00 -0.73 0.1839 264PHD1_YPD HTZ1 Krogan04 -0.73 0.1839 61GLN3_RAPA WT_WT Chitikila_02 -0.73 0.1839 64MSN2_H2O2Hiisw2_sin3 Fazzio01 0.73 0.1839 75RLM1_YPD IES6 Hughes00 0.73 0.184 54AFT2_H2O2Hi htz1_del Mizuguch04 0.73 0.184 60SKN7_H2O2HiSet1_del Bernstein02 0.73 0.1841 96HAP1_YPD H3KQ Sabet04 0.73 0.1841 137MBP1_YPD hat2_vs._YPH250Rosaleny05 -0.73 0.1841 122YAP1_YPD taf1-ts2_gcn5_KQLHuisinga04 0.73 0.1842 56RLM1_YPD H4KQ Sabet04 0.73 0.1843 50PHD1_BUT90 taf1-ts2_25C Huisinga04 0.73 0.1843 101GCN4_YPD Dsds3 Keogh05 0.73 0.1843 64ABF1_YPD WT_Null_K Chitikila_02 0.73 0.1844 251CBF1_SM SIN3 Hughes00 0.73 0.1844 277PUT3_H2O2Lo WT_TAF1_GCN5Huisinga04 0.73 0.1845 86MBP1_YPD WT Durant06 0.73 0.1845 123DAL82_SM SWD2 Mnaimneh_04 0.73 0.1846 55DIG1_BUT14 HST3 Hughes00 -0.73 0.1846 63ROX1_YPD esa1-414 Durant06 -0.73 0.1847 61RCS1_H2O2Lorpd3 Fazzio01 0.73 0.1847 253YAP6_H2O2Lo DM_vs._YPH250Rosaleny05 0.73 0.1848 50CIN5_YPD SPT3 Ingvarsdottir05 -0.73 0.1849 129

SKN7_H2O2Lohat1D Durant06 0.73 0.1849 129PHD1_YPD arp8 Attikum04 0.73 0.1851 48DAL82_RAPA ume6_del Bernstein_00_affydeletions0.73 0.1851 52FKH2_H2O2Hi isw2_ume6 Fazzio01 -0.73 0.1854 104XBP1_H2O2Lo htz1 Meneghini03 -0.73 0.1854 67ACE2_YPD HTZ1 Krogan04 0.73 0.1854 72SKN7_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 -0.73 0.1855 98SUT1_YPD elp3D_taf1-ts2Durant06 0.73 0.1856 50RPN4_H2O2Loswr1_del Mizuguch04 0.73 0.1856 100SOK2_BUT14 taf1-ts2 Durant06 0.73 0.1856 71OAF1_YPD hht2K9131823GMartin04 0.73 0.1857 44PHD1_YPD sas3D Durant06 -0.73 0.1858 54RLM1_YPD BUR6 Geisberg_01 -0.73 0.1859 50GCR2_SM swr1_del Mizuguch04 0.73 0.1859 54SWI4_YPD DT_Null Chitikila_02 0.73 0.186 150SWI6_YPD EAF5 Krogan04 0.73 0.186 136XBP1_H2O2Lo RAD6_haploid Hughes00 0.73 0.1861 67SKN7_YPD Rpd3_del Bernstein02 0.73 0.1862 65SKN7_H2O2Losin3 Fazzio01 -0.72 0.1863 181SOK2_BUT14 hos3_del Bernstein_00_affydeletions-0.72 0.1865 59REB1_YPD taf1-ts2_gcn5_KQLHuisinga04 -0.72 0.1866 128STP1_SM rsc30_null Angus-Hill_01 -0.72 0.1866 65MSN4_H2O2HiSWC6_(VPS71)Krogan04 0.72 0.1866 62ROX1_YPD HST3 Hughes00 0.72 0.1869 67TYE7_YPD DT_V161R_K Chitikila_02 -0.72 0.1869 52GCN4_SM rpd3_del Sabet04 0.72 0.1869 185DAL81_RAPA rpd3_H4KQ_v_H4KQSabet04 -0.72 0.187 94MCM1_Alpha SSN6_haploid Hughes00 0.72 0.187 105MCM1_Alpha H3_1-28 Sabet04 0.72 0.187 103CBF1_SM PCH1 Hughes00 0.72 0.1871 274RTG3_RAPA SPT8 Ingvarsdottir05 -0.72 0.1872 44CBF1_SM hat1D_taf1-ts2Durant06 0.72 0.1873 226DIG1_BUT14 hat2_vs._YPH250Rosaleny05 -0.72 0.1873 60STP1_SM esa1-414 Durant06 0.72 0.1874 60DAL82_RAPA hpa2D_taf1-ts2Durant06 0.72 0.1876 42RLM1_YPD WT_N69S Chitikila_02 -0.72 0.1877 50ROX1_YPD YNG2 Krogan04 0.72 0.1877 63SUM1_YPD htz1_hmr Meneghini03 -0.72 0.1879 55SUT1_YPD htz1_del Mizuguch04 -0.72 0.1881 68MSN4_H2O2HiHda1_del Bernstein02 0.72 0.1883 68RCS1_H2O2LoIES6 Hughes00 0.72 0.1884 255ASH1_BUT14 Dsap30 Keogh05 0.72 0.1885 50PHD1_BUT90 HIR2 Hughes00 0.72 0.1885 103FKH1_YPD YNG2 Krogan04 0.72 0.1886 136MSN2_H2O2Hirpd3 Fazzio01 0.72 0.1888 75SKN7_H2O2Hi elp3D Durant06 0.72 0.1888 80SWI6_YPD taf1-ts2_SPT3 Huisinga04 0.72 0.1889 144TYE7_YPD isw2 Fazzio01 0.72 0.189 54MSN4_H2O2HiWT_TAF1_SPT3Huisinga04 -0.72 0.189 69XBP1_H2O2Lo H3KQ Sabet04 -0.72 0.1891 56PHO4_YPD DT_V71E Chitikila_02 0.72 0.1892 70FKH2_H2O2Hi hht2_K4G Martin04 0.72 0.1892 90AFT2_H2O2Lo htz1_del Mizuguch04 0.72 0.1893 97

NRG1_H2O2Hihos3_del Bernstein_00_affydeletions-0.72 0.1894 111ASH1_BUT14 WT_TAF1_GCN5Huisinga04 0.72 0.1894 49MCM1_YPD UBP8 Hughes00 0.72 0.1894 76PHD1_YPD elp3D Durant06 0.72 0.1896 50SOK2_BUT14 Dsds3 Keogh05 -0.72 0.1896 66NRG1_YPD DT_N69R Chitikila_02 0.72 0.1896 64MBP1_H2O2Loisw2_ume6 Fazzio01 0.72 0.1898 54STE12_BUT90 MED2_haploid Hughes00 -0.72 0.1899 76SWI5_YPD YNG2 Mnaimneh_04 0.72 0.19 102ASH1_BUT14 RAD6_haploid Hughes00 -0.72 0.19 49STE12_BUT90 taf1-ts2_25C Huisinga04 0.72 0.19 70PUT3_H2O2Lo SIR1 Hughes00 0.72 0.1903 87CIN5_YPD DT_N69R Chitikila_02 -0.72 0.1904 141CIN5_H2O2Lo hos2_del Bernstein_00_affydeletions-0.72 0.1904 109NDD1_YPD SSN6_haploid Hughes00 0.72 0.1904 85UME6_H2O2Hirsc3-2 Angus-Hill_01 0.72 0.1905 101FKH2_H2O2Hi SIR1 Hughes00 -0.71 0.1908 105DAL82_RAPA hat2_vs._YPH250Rosaleny05 0.71 0.191 50MBP1_H2O2Hi0.1%_MMS Attikum04 -0.71 0.191 106STE12_Alpha rpd3_H3dN_v_H3dNSabet04 -0.71 0.1911 109YAP1_YPD YNG2 Krogan04 0.71 0.1912 69YAP7_H2O2Hi DT_V161R_L Chitikila_02 0.71 0.1912 131SWI4_YPD SIR4 Hughes00 0.71 0.1913 156REB1_H2O2Hi isw2_sin3 Fazzio01 0.71 0.1913 57XBP1_H2O2Lo _SWC2_(VPS72)Krogan04 -0.71 0.1913 66MCM1_YPD Drxt2 Keogh05 0.71 0.1913 75HSF1_H2O2Hi WT_V161R_L Chitikila_02 -0.71 0.1914 120RLM1_YPD Dsap30 Keogh05 -0.71 0.1916 55DAL82_SM Dume1 Keogh05 -0.71 0.1916 45MBP1_H2O2LoDeaf3 Keogh05 0.71 0.1916 53RCS1_H2O2Logcn5 Huisinga04 0.71 0.1916 244SUM1_YPD Dume1 Keogh05 -0.71 0.1917 51YAP6_YPD TAF2 Mnaimneh_04 0.71 0.1917 91FKH2_YPD SSD1-V Kaeberlein04 0.71 0.1918 121SUM1_YPD htz1_del Mizuguch04 -0.71 0.192 59CIN5_H2O2Lo H3KQ Sabet04 0.71 0.1921 119SUM1_YPD taf1-ts2_25C Huisinga04 -0.71 0.1922 50NRG1_H2O2Hihtz1 Meneghini03 -0.71 0.1922 122PHD1_BUT90 elp3D Durant06 0.71 0.1922 87PHD1_YPD Dsin3 Keogh05 -0.71 0.1923 57AFT2_H2O2Hi ume6 Fazzio01 0.71 0.1923 58MBP1_H2O2Higcn5D Durant06 -0.71 0.1923 108UME6_YPD ZDS1 Hughes00 0.71 0.1924 126MSN4_RAPA PCH1 Hughes00 -0.71 0.1924 51STE12_Alpha WT_TAF1_SPT3Huisinga04 0.71 0.1924 111NDD1_YPD SIR1 Hughes00 0.71 0.1925 84YAP1_YPD WT_N69R Chitikila_02 -0.71 0.1927 67CIN5_H2O2Hi taf1-ts2_SPT3 Huisinga04 -0.71 0.1928 76MCM1_Alpha ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.71 0.1931 90FKH2_H2O2Hi HIR2 Hughes00 -0.71 0.1932 105MSN4_H2O2HiSPT3 Ingvarsdottir05 0.71 0.1932 62OAF1_YPD DT_N69R Chitikila_02 -0.71 0.1933 51FKH2_YPD Drco1 Keogh05 0.71 0.1936 113

YAP6_H2O2Lo swr1_del Mizuguch04 -0.71 0.1937 59ABF1_YPD ubp10 Orlandi04 -0.71 0.1938 212DIG1_Alpha snf2_minimal_medium_experimentSudarsanam00 -0.71 0.1938 59PHD1_YPD SIN3 Hughes00 -0.71 0.194 65YAP6_H2O2Hi WT_TAF1_GCN5Huisinga04 -0.71 0.1941 77SKN7_YPD hht2_K914182327GMartin04 0.71 0.1942 52MSN4_H2O2HiDT_N69S Chitikila_02 -0.71 0.1942 67CBF1_SM isw2_c.i. Fazzio01 0.71 0.1943 272YAP1_YPD WT_V161R_L Chitikila_02 -0.71 0.1944 70YAP7_H2O2Hi WT_N69R Chitikila_02 -0.71 0.1944 133STP1_SM hos2_del Bernstein_00_affydeletions-0.71 0.1945 64DAL82_RAPA spt10 Eriksson05 -0.71 0.1945 55NRG1_YPD WT_V161R_L Chitikila_02 -0.71 0.1946 67PHO4_YPD ubp10sir4 Orlandi04 0.71 0.1947 50NRG1_H2O2HiH3KQ Sabet04 0.71 0.1947 120DAL82_RAPA isw2_sin3_vs._sin3Fazzio01 -0.7 0.195 54MBP1_H2O2Hi isw2_ume6 Fazzio01 0.7 0.1951 126SKN7_YPD gcn5 Huisinga04 -0.7 0.1953 67DAL82_SM VID21 Krogan04 0.7 0.1953 46DIG1_BUT14 elp3D_taf1-ts2Durant06 0.7 0.1953 48GCN4_YPD isw2_ume6 Fazzio01 0.7 0.1953 74MBP1_YPD sas3D Durant06 -0.7 0.1953 103STE12_YPD elp3D Durant06 -0.7 0.1955 43CIN5_YPD SIR4 Hughes00 -0.7 0.1955 150PHD1_YPD EAF5 Krogan04 -0.7 0.1956 58STE12_YPD ISW1_ISW2 Hughes00 0.7 0.1956 54YAP7_H2O2Lo DM_vs._YPH250Rosaleny05 0.7 0.1958 145PUT3_H2O2Lo set1 Boa03 -0.7 0.1959 87YAP7_H2O2Lo SSD1-V Kaeberlein04 0.7 0.1959 151CIN5_H2O2Lo RSC8 Mnaimneh_04 0.7 0.196 127GCN4_RAPA hpa2D Durant06 0.7 0.1961 134SWI4_YPD Drco1 Keogh05 0.7 0.1962 147HAP4_YPD DT_Null Chitikila_02 0.7 0.1962 64YAP7_H2O2Lo SPT3 Ingvarsdottir05 0.7 0.1963 133NDD1_YPD ino80_del Mizuguch04 0.7 0.1963 84GCR2_SM isw2_c.i._rpd3_c.i.Fazzio01 -0.7 0.1965 52RTG3_RAPA HAT2 Hughes00 -0.7 0.1966 52RCS1_H2O2Hi DT_N69R Chitikila_02 0.7 0.1967 47YAP6_H2O2Lo ume6_del Bernstein_00_affydeletions0.7 0.1968 50NDD1_YPD spt3 Huisinga04 -0.7 0.1968 82PHD1_YPD gcn5D Durant06 0.7 0.197 52GCN4_YPD isw2_c.i. Fazzio01 -0.7 0.197 74HAP4_YPD swi1_rich_medium_experimentSudarsanam00 -0.7 0.197 67OAF1_YPD taf1-ts2_25C Huisinga04 -0.7 0.1971 55GCR2_SM HST3 Hughes00 -0.7 0.1972 53XBP1_H2O2Lo YNG2 Krogan04 0.7 0.1973 65RTG3_RAPA WT_TAF1_SPT3Huisinga04 -0.7 0.1974 52AFT2_H2O2Hi TAF2 Mnaimneh_04 0.7 0.1974 61YAP7_H2O2Lo Dsin3 Keogh05 0.7 0.1974 127YAP1_YPD gcn5D Durant06 0.7 0.1976 62YAP7_H2O2Hi SPT8 Ingvarsdottir05 0.7 0.1977 126HAP4_YPD isw2_ume6 Fazzio01 -0.7 0.1977 64DAL81_RAPA TUP1_haploid Hughes00 0.7 0.1979 95

FKH1_YPD SSN6_haploid Hughes00 -0.7 0.1981 140MSN2_H2O2Hitaf1-ts2_25C Huisinga04 -0.7 0.1982 69SWI5_YPD DT_N69S Chitikila_02 -0.7 0.1983 86PUT3_H2O2Lo MED2_haploid Hughes00 0.7 0.1983 88NRG1_YPD HAT2 Hughes00 0.7 0.1983 72CIN5_H2O2Hi spt10_del Xu05 -0.7 0.1984 79SKN7_H2O2Hi swi1_rich_medium_experimentSudarsanam00 -0.7 0.1984 98PUT3_H2O2Lo taf1-ts2_spt3_E240KHuisinga04 0.7 0.1985 81UME6_YPD ino80 Attikum04 0.7 0.1986 85RCS1_H2O2Hi SGF11 Ingvarsdottir05 0.7 0.1986 45DIG1_BUT14 Hda1_del Bernstein02 0.7 0.1986 63SUM1_YPD SSN6_haploid Hughes00 -0.7 0.1987 54CBF1_SM SIR1 Hughes00 0.7 0.1987 277STE12_BUT14 hht2_K4G Martin04 -0.7 0.1987 110DIG1_Alpha hht2_K4914182327GMartin04 -0.7 0.1989 41PHD1_BUT90 Drco1 Keogh05 0.7 0.1989 99CIN5_H2O2Hi WT_N69R Chitikila_02 0.7 0.199 73TYE7_YPD SAP30 Hughes00 -0.7 0.1991 55NRG1_H2O2Higcn5 Huisinga04 0.7 0.1991 118PHD1_BUT90 sas3D Durant06 -0.7 0.1991 91MCM1_YPD WT_N69S Chitikila_02 0.7 0.1993 65GLN3_RAPA WT_Null_L Chitikila_02 0.7 0.1994 60PHD1_YPD SPT8 Ingvarsdottir05 -0.69 0.1996 62MBP1_YPD taf1-ts2_25C Huisinga04 0.69 0.1999 119GCN4_SM hat1D Durant06 -0.69 0.2001 145REB1_H2O2Hi DT_N69R Chitikila_02 0.69 0.2001 54MBP1_H2O2Lohos3_del Bernstein_00_affydeletions-0.69 0.2001 55PHD1_YPD WT_Null_L Chitikila_02 0.69 0.2002 66GCR2_SM arp8 Attikum04 -0.69 0.2002 43GCN4_RAPA MOT1-42 Dasgupta02 0.69 0.2004 159MCM1_YPD DT_Null Chitikila_02 0.69 0.2004 72AFT2_H2O2Hi hpa2D Durant06 -0.69 0.2006 52MBP1_H2O2LoSIR4 Hughes00 0.69 0.2006 58STE12_Alpha isw2_sin3_vs._sin3Fazzio01 -0.69 0.2007 112ROX1_YPD sir2 Meneghini03 0.69 0.2008 66RCS1_H2O2Lohht2K9131823GMartin04 0.69 0.2008 227YAP6_YPD taf1-ts2_spt3_E240KHuisinga04 -0.69 0.2009 82STP1_SM WT_V161R_L Chitikila_02 -0.69 0.2009 64GLN3_RAPA rpd3_del Sabet04 0.69 0.2009 66HAP4_YPD ISW2 Hughes00 0.69 0.201 67HAP4_YPD YAF9 Krogan04 0.69 0.201 59STE12_Alpha WT_Null_L Chitikila_02 0.69 0.2013 110HSF1_H2O2Lo ino80_del Mizuguch04 -0.69 0.2014 100NRG1_H2O2HiSWC6_(VPS71)Krogan04 0.69 0.2016 109HSF1_H2O2Hi HST3 Hughes00 0.69 0.2017 122SUT1_YPD H3KQ Sabet04 0.69 0.2018 66FKH2_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 0.69 0.2018 102GCN4_RAPA taf1-ts2_spt3_E240KHuisinga04 0.69 0.2019 149DAL82_SM ino80_del Mizuguch04 0.69 0.202 55NDD1_YPD Drxt2 Keogh05 0.69 0.202 81STP1_SM WT_V71R Chitikila_02 -0.69 0.2021 61REB1_YPD ARP4 Mnaimneh_04 -0.69 0.2022 145SUT1_YPD SWD2 Mnaimneh_04 0.69 0.2023 69

HSF1_H2O2LoH3KQ Sabet04 0.69 0.2023 97STE12_Alpha WT_V161R_L Chitikila_02 0.69 0.2024 103TYE7_YPD DT_V161E Chitikila_02 -0.69 0.2025 52AFT2_H2O2Lo DT_V161E Chitikila_02 -0.69 0.2026 92REB1_H2O2Hi _SWC2_(VPS72)Krogan04 -0.69 0.2027 54YAP6_H2O2Hi elp3D Durant06 -0.69 0.2027 61CIN5_H2O2Lo MED2_haploid Hughes00 0.69 0.2027 126YAP7_H2O2Hi RPD3_haploid Hughes00 0.69 0.2028 139MSN2_H2O2Hisnf2_rich_medium_experimentSudarsanam00 0.69 0.2029 78GCR2_SM htz1 Meneghini03 0.69 0.203 53MCM1_YPD DT_N69R Chitikila_02 0.69 0.203 71GLN3_RAPA TAF2 Mnaimneh_04 -0.69 0.2031 68RIM101_H2O2Loarp8_+_0.1%_MMS_vs._arp8Attikum04 -0.69 0.2033 33SUT1_YPD DT_N69S Chitikila_02 0.69 0.2034 63PHD1_BUT90 DT_V161R_L Chitikila_02 0.69 0.2034 99STE12_YPD WT_V161R_L Chitikila_02 -0.69 0.2035 46GLN3_RAPA hat2_vs._YPH250Rosaleny05 -0.69 0.2035 63SOK2_BUT14 htz1_del Mizuguch04 -0.69 0.2035 71OAF1_YPD htz1 Meneghini03 0.69 0.2035 59MCM1_Alpha SWD2 Mnaimneh_04 0.69 0.2036 106FKH2_H2O2Hi swr1 Meneghini03 0.69 0.2037 89GCN4_YPD rpd3 Fazzio01 0.69 0.2038 74UME6_YPD WT_N69R Chitikila_02 -0.69 0.2039 119RPN4_H2O2LoSIR4 Hughes00 0.69 0.204 99DAL81_RAPA ARP4 Mnaimneh_04 0.69 0.2041 95DAL82_RAPA BUR6 Geisberg_01 0.68 0.2042 51RTG3_RAPA DT_Null Chitikila_02 0.68 0.2042 50STE12_Alpha WT Durant06 -0.68 0.2042 108HSF1_H2O2LoSSD1-V Kaeberlein04 0.68 0.2043 101YAP6_H2O2Lo ino80 Attikum04 0.68 0.2043 41REB1_H2O2Hi IOC4 Hughes00 -0.68 0.2044 59REB1_H2O2Hi ISW1_ISW2 Hughes00 -0.68 0.2048 59ACE2_YPD hht2_K4914182327GMartin04 0.68 0.2048 65DAL81_RAPA MOT1-42 Dasgupta02 0.68 0.2049 95AFT2_H2O2Lo hmr Meneghini03 0.68 0.2049 93SUT1_YPD DM_vs._YPH250Rosaleny05 0.68 0.205 56GCN4_SM swr1 Meneghini03 0.68 0.205 158DAL82_RAPA MOT1-42 Dasgupta02 0.68 0.205 56MSN4_RAPA SIR2 Hughes00 -0.68 0.205 54STP1_SM SIR3 Hughes00 0.68 0.2051 67RLM1_YPD ISW1_ISW2 Hughes00 -0.68 0.2052 54GCN4_YPD hht2_K4914182327GMartin04 0.68 0.2052 66DIG1_BUT14 Rpd3_del Bernstein02 -0.68 0.2053 62NDD1_YPD DT_V161E Chitikila_02 -0.68 0.2053 81SWI6_YPD spt10_del Xu05 -0.68 0.2054 149CIN5_H2O2Hi ubp10sir4 Orlandi04 -0.68 0.2055 43MCM1_Alpha WT_WT Chitikila_02 -0.68 0.2055 102GLN3_RAPA DT_V161R_L Chitikila_02 -0.68 0.2057 60PHO4_YPD ISW1_ISW2 Hughes00 -0.68 0.2058 70YAP6_H2O2Hi SIR4 Hughes00 0.68 0.2058 78SWI4_YPD HIR2 Hughes00 -0.68 0.206 154GLN3_RAPA Drco1 Keogh05 0.68 0.206 64HSF1_H2O2LoDsds3 Keogh05 0.68 0.2061 92

PHD1_BUT90 H3KQ Sabet04 0.68 0.2061 96MGA1_YPD MED2_haploid Hughes00 0.68 0.2061 62REB1_YPD WT_TAF1_GCN5Huisinga04 0.68 0.2062 139ROX1_YPD ume6 Fazzio01 0.68 0.2062 67SWI4_YPD hht2_K4G Martin04 -0.68 0.2062 129GCR2_SM swi1_rich_medium_experimentSudarsanam00 -0.68 0.2064 54PUT3_H2O2Lo arp8 Attikum04 -0.68 0.2064 64DAL81_RAPA RPD3_haploid Hughes00 0.68 0.2065 93AFT2_H2O2Hi rpd3_H3dN_v_H3dNSabet04 0.68 0.2065 56HSF1_H2O2Hi set1 Boa03 0.68 0.2065 119SKN7_YPD SPT8 Ingvarsdottir05 -0.68 0.2067 57CBF1_SM ubp10sir4 Orlandi04 -0.68 0.2067 209MBP1_H2O2Hihtz1_del Mizuguch04 0.68 0.2067 133SUM1_YPD SWD2 Mnaimneh_04 0.68 0.2068 59TYE7_YPD RAD6_haploid Hughes00 -0.68 0.2068 55YAP6_YPD H3KQ Sabet04 0.68 0.2068 82RIM101_H2O2LoSWR1 Krogan04 -0.68 0.2068 48CIN5_YPD taf1-ts2_spt3_E240KHuisinga04 -0.68 0.2069 132DIG1_BUT14 spt10_del Xu05 -0.68 0.2069 63NDD1_YPD SIR3 Hughes00 0.68 0.2069 85NRG1_YPD Dsin3 Keogh05 -0.68 0.2069 61SKN7_YPD H3KQ Sabet04 -0.68 0.207 62TYE7_YPD isw2_ume6 Fazzio01 -0.68 0.2071 54SKN7_H2O2LoSAP30 Hughes00 0.68 0.2072 184YAP7_H2O2Hi ISW1 Hughes00 -0.68 0.2073 139MBP1_H2O2Lohht2_K49141823GMartin04 0.68 0.2074 45FKH2_H2O2Hi TAF2 Mnaimneh_04 0.68 0.2075 106YAP7_H2O2Lo _SWC2_(VPS72)Krogan04 0.68 0.2078 140SOK2_BUT14 hpa2D_taf1-ts2Durant06 0.68 0.208 49YAP6_YPD WT_WT Chitikila_02 -0.68 0.2084 88YAP7_H2O2Hi hht2_K4G Martin04 0.68 0.2085 116RCS1_H2O2LoSIN3 Hughes00 0.68 0.2085 255REB1_YPD swr1_del Mizuguch04 -0.68 0.2087 144RLM1_YPD DM_vs._YPH250Rosaleny05 0.68 0.2088 52STE12_BUT90 hat1D_taf1-ts2Durant06 0.68 0.2089 68RCS1_H2O2Lotaf1-ts2_GCN5Huisinga04 0.67 0.209 238CIN5_YPD BUR6 Geisberg_01 0.67 0.2091 144HSF1_H2O2Hi WT Durant06 0.67 0.2092 115NRG1_H2O2Hihat2_vs._hat1Rosaleny05 -0.67 0.2092 113GCN4_YPD spt10 Eriksson05 -0.67 0.2092 75NDD1_YPD SPT3 Ingvarsdottir05 0.67 0.2092 78SWI5_YPD ubp10sir4 Orlandi04 -0.67 0.2093 73UME6_H2O2Hiubp10sir4 Orlandi04 -0.67 0.2094 58RCS1_H2O2LoYAF9 Krogan04 0.67 0.2094 247STE12_BUT90 snf2_minimal_medium_experimentSudarsanam00 -0.67 0.2094 76STE12_BUT90 ume6 Fazzio01 -0.67 0.2094 77MCM1_YPD rsc3-2 Angus-Hill_01 0.67 0.2094 74AFT2_H2O2Hi SWD2 Mnaimneh_04 0.67 0.2095 61MBP1_YPD sir2 Meneghini03 -0.67 0.2096 129STE12_BUT14 IES6 Hughes00 -0.67 0.2097 128MBP1_H2O2LoDT_WT Chitikila_02 -0.67 0.2098 52MBP1_H2O2Lohat1D_taf1-ts2Durant06 -0.67 0.2099 47DIG1_BUT14 ISW1_ISW2 Hughes00 -0.67 0.2099 63

ABF1_YPD Drpd3 Keogh05 -0.67 0.2101 241YAP6_H2O2Lo hat2_vs._hat1Rosaleny05 -0.67 0.2102 54PHD1_BUT90 SIN3 Hughes00 -0.67 0.2102 105SUT1_YPD htz1 Meneghini03 0.67 0.2106 65YAP1_YPD hat1D_taf1-ts2Durant06 -0.67 0.2106 63DIG1_Alpha taf1-ts2_spt3 Huisinga04 -0.67 0.2106 55HAP1_YPD gcn5_KQL Huisinga04 0.67 0.2106 119RTG3_RAPA H3_1-28 Sabet04 0.67 0.2108 50ROX1_YPD Drxt1 Keogh05 -0.67 0.2113 66SUM1_YPD sir4 Orlandi04 -0.67 0.2113 21MBP1_H2O2HiSet1_del Bernstein02 -0.67 0.2114 128SUM1_YPD YAF9 Krogan04 -0.67 0.2115 49NDD1_YPD gcn5_KQL Huisinga04 -0.67 0.2115 75MSN4_RAPA TAF2 Mnaimneh_04 -0.67 0.2116 54HSF1_H2O2LoSWC6_(VPS71)Krogan04 0.67 0.2116 89REB1_H2O2Hi ume6 Fazzio01 -0.67 0.2117 56RIM101_H2O2Lohtz1_del Mizuguch04 -0.67 0.212 52SUT1_YPD hat1D Durant06 -0.67 0.2123 51DAL81_RAPA taf1-ts2_25C Huisinga04 0.67 0.2123 87FKH1_YPD WT_Null_K Chitikila_02 0.67 0.2123 136MSN2_H2O2HiISW1 Hughes00 0.67 0.2125 77MBP1_H2O2HiUBP8 Ingvarsdottir05 0.67 0.2126 123YAP6_H2O2Lo SWD2 Mnaimneh_04 -0.67 0.2126 59UME6_H2O2HiTAF2 Mnaimneh_04 0.67 0.2127 102FKH2_H2O2Hi Drco1 Keogh05 0.67 0.2128 98STE12_BUT90 SIR4 Hughes00 -0.67 0.2128 78CIN5_H2O2Lo set1 Boa03 0.67 0.2131 127CIN5_YPD hht2_K4914182327GMartin04 0.67 0.2132 116DAL82_RAPA taf1-ts2 Durant06 0.67 0.2132 56GLN3_RAPA sir4 Orlandi04 -0.67 0.2132 50MBP1_H2O2Hi PCH1 Hughes00 -0.67 0.2132 132STE12_BUT90 ISW2 Hughes00 -0.67 0.2132 78MGA1_YPD SWC6_(VPS71)Krogan04 0.67 0.2132 54REB1_YPD EPL1 Mnaimneh_04 -0.67 0.2133 145YAP6_YPD H4_2-26 Sabet04 0.67 0.2135 82FKH2_H2O2Hi gcn5D_taf1-ts2Durant06 0.67 0.2135 101YAP7_H2O2Lo rpd3_H3dN_v_H3dNSabet04 0.67 0.2136 147SWI4_YPD Dsds3 Keogh05 0.66 0.2138 147CIN5_H2O2Hi isw2_ume6 Fazzio01 0.66 0.2138 79REB1_H2O2Hi H4_2-26 Sabet04 -0.66 0.2138 57TYE7_YPD Drco1 Keogh05 0.66 0.2139 55NRG1_H2O2Hisap30_del Bernstein_00_affydeletions0.66 0.2139 111MBP1_H2O2LoSet1_del Bernstein02 -0.66 0.2139 57TYE7_YPD 0.1%_MMS Attikum04 -0.66 0.214 51MSN4_RAPA sir2 Meneghini03 -0.66 0.214 50SUM1_YPD DT_N69R Chitikila_02 -0.66 0.2141 51ACE2_YPD hat1D_taf1-ts2Durant06 0.66 0.2141 62SUM1_YPD taf1-ts2_gcn5 Huisinga04 0.66 0.2142 52ASH1_BUT14 EAF5 Krogan04 0.66 0.2142 43TYE7_YPD SSD1-V Kaeberlein04 0.66 0.2146 55YAP7_H2O2Hi EAF5 Krogan04 0.66 0.2146 125PUT3_H2O2Lo isw2_rpd3 Fazzio01 -0.66 0.2146 86RLM1_YPD SAP30 Hughes00 -0.66 0.2147 53

STE12_BUT14 WT_N69S Chitikila_02 -0.66 0.2147 114MCM1_Alpha RSC8 Mnaimneh_04 0.66 0.2148 106NDD1_YPD rsc3-2 Angus-Hill_01 0.66 0.2152 83REB1_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 0.66 0.2153 58YAP6_H2O2Lo taf1-ts2_gcn5 Huisinga04 -0.66 0.2153 55ABF1_YPD Rpd3_del Bernstein02 -0.66 0.2154 263FKH2_H2O2Hi SIR3 Hughes00 -0.66 0.2154 105ROX1_YPD taf1-ts2_gcn5 Huisinga04 -0.66 0.2156 65YAP6_H2O2Lo DT_Null Chitikila_02 -0.66 0.2157 55YAP6_H2O2Lo SSD1-V Kaeberlein04 -0.66 0.216 58STE12_YPD EAF7 Krogan04 0.66 0.2161 51RCS1_H2O2LoISW1 Hughes00 0.66 0.2162 257YAP6_H2O2Lo WT_V71R Chitikila_02 0.66 0.2164 52FKH2_H2O2Hi DT_N69S Chitikila_02 0.66 0.2165 93CIN5_H2O2Lo hat1_vs.YPH250Rosaleny05 0.66 0.2165 116MSN4_RAPA WT_V161E Chitikila_02 0.66 0.2168 51NRG1_H2O2Hihht2_K49141823GMartin04 -0.66 0.2168 83STP1_SM ino80_+_0.1%_MMS_vs._ino80Attikum04 0.66 0.217 49FKH1_YPD SSD1-V Kaeberlein04 0.66 0.217 142SKN7_H2O2Lohht2_K49141823GMartin04 0.66 0.2171 146AFT2_H2O2Lo hpa2D Durant06 -0.66 0.2173 80HAP1_YPD ISW2 Hughes00 -0.66 0.2173 140UME6_YPD htz1_hmr Meneghini03 0.66 0.2175 127STP1_SM gcn5D_taf1-ts2Durant06 0.66 0.2175 60DAL81_RAPA EAF7 Krogan04 0.66 0.2175 85YAP6_H2O2Lo swi1_rich_medium_experimentSudarsanam00 0.66 0.2177 58SOK2_BUT14 RSC8 Mnaimneh_04 0.66 0.2177 72ASH1_BUT14 MED2_haploid Hughes00 -0.66 0.2178 50STE12_BUT90 gcn5_KQL Huisinga04 -0.66 0.2178 66YAP7_H2O2Hi WT_Null_K Chitikila_02 0.66 0.218 137DIG1_BUT14 gcn5_KQL Huisinga04 -0.66 0.218 55CIN5_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 0.66 0.2181 80REB1_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 0.66 0.2181 58RCS1_H2O2Loume6 Fazzio01 0.66 0.2185 252AFT2_H2O2Hi _SWC2_(VPS72)Krogan04 -0.66 0.2187 56SKN7_H2O2Hi hpa2D Durant06 -0.66 0.2187 70YAP7_H2O2Lo htz1 Meneghini03 0.66 0.2187 145DIG1_Alpha RSC8 Mnaimneh_04 0.65 0.2188 60DIG1_Alpha hmr Meneghini03 -0.65 0.2188 59HAP4_YPD WT_Null_L Chitikila_02 0.65 0.2188 62RTG3_RAPA hos3_del Bernstein_00_affydeletions0.65 0.2189 47CIN5_H2O2Lo Dsds3 Keogh05 -0.65 0.2189 120YAP6_H2O2Lo elp3D_taf1-ts2Durant06 -0.65 0.2189 35AFT2_H2O2Hi HAT2 Hughes00 0.65 0.2191 60HAP4_YPD elp3D_taf1-ts2Durant06 -0.65 0.2192 53YAP7_H2O2Hi HTZ1 Krogan04 0.65 0.2193 125STP1_SM elp3D_taf1-ts2Durant06 0.65 0.2194 50DIG1_BUT14 isw2_sin3_vs._sin3Fazzio01 -0.65 0.2194 63NRG1_H2O2HiDM_vs._YPH250Rosaleny05 0.65 0.2195 105UME6_H2O2HiISW2 Hughes00 -0.65 0.2195 101CIN5_H2O2Lo gcn5 Huisinga04 0.65 0.2195 116MBP1_H2O2LoEPL1 Mnaimneh_04 0.65 0.2195 58SUM1_YPD WT_Null_K Chitikila_02 -0.65 0.2196 45

MCM1_Alpha SSD1-V Kaeberlein04 0.65 0.2198 106CIN5_H2O2Hi H4KQ Sabet04 0.65 0.2199 74ABF1_YPD esa1-414_taf1-ts2Durant06 -0.65 0.2201 252MGA1_YPD rsc3-2 Angus-Hill_01 -0.65 0.2201 60GLN3_RAPA spt3 Huisinga04 -0.65 0.2202 67NRG1_YPD WT_N69S Chitikila_02 0.65 0.2203 64CIN5_YPD sap30_del Bernstein_00_affydeletions-0.65 0.2205 137XBP1_H2O2Lo hht2K9131823GMartin04 0.65 0.2205 44PHO4_YPD WT_TAF1_GCN5Huisinga04 0.65 0.2207 71YAP6_H2O2Lo ubp10sir4 Orlandi04 -0.65 0.2207 29PHO4_YPD IES6 Hughes00 0.65 0.2208 70REB1_YPD arp8 Attikum04 -0.65 0.2209 110DIG1_BUT14 H4_2-26 Sabet04 -0.65 0.2209 63MGA1_YPD WT_N69S Chitikila_02 0.65 0.221 53CIN5_H2O2Lo swr1_del Mizuguch04 -0.65 0.2211 127CIN5_H2O2Lo WT_N69R Chitikila_02 -0.65 0.2211 113RIM101_H2O2LoDpho23 Keogh05 -0.65 0.2211 53STE12_Alpha HDA1 Hughes00 -0.65 0.2211 115STE12_YPD H4_2-26 Sabet04 -0.65 0.2212 51GCN4_YPD H3KQ Sabet04 0.65 0.2212 75SWI5_YPD taf1-ts2_25C Huisinga04 0.65 0.2213 91MSN4_RAPA UBP8 Ingvarsdottir05 0.65 0.2214 49SUM1_YPD WT_TAF1_SPT3Huisinga04 -0.65 0.2215 54AFT2_H2O2Hi htz1_sir2 Meneghini03 0.65 0.2215 61DIG1_Alpha hat1D_taf1-ts2Durant06 0.65 0.2215 46SUM1_YPD Deaf3 Keogh05 0.65 0.2216 54YAP6_YPD htz1_sir2 Meneghini03 -0.65 0.2216 90MSN4_RAPA RSC8 Mnaimneh_04 -0.65 0.2217 54MSN2_H2O2Hihht2K9131823GMartin04 0.65 0.2217 66YAP7_H2O2Hi UBP8 Ingvarsdottir05 0.65 0.2217 134REB1_YPD ino80_del Mizuguch04 0.65 0.2219 143CBF1_SM isw2_ume6 Fazzio01 -0.65 0.2219 272CIN5_H2O2Hi hat2_vs._YPH250Rosaleny05 0.65 0.2221 76RCS1_H2O2Hi RPD3_haploid Hughes00 0.65 0.2221 52SOK2_BUT14 Dsin3 Keogh05 -0.65 0.2221 57RTG3_RAPA H3KQ Sabet04 0.65 0.2222 50CIN5_H2O2Hi htz1_sir2 Meneghini03 -0.65 0.2224 79REB1_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 0.65 0.2224 47STE12_YPD isw2 Fazzio01 -0.65 0.2225 54HSF1_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 -0.65 0.2225 122HSF1_H2O2Hi Dume1 Keogh05 -0.65 0.2228 114MBP1_H2O2Loelp3D Durant06 0.65 0.2228 42MSN2_H2O2HiSPT8 Ingvarsdottir05 0.65 0.223 73CIN5_H2O2Lo elp3D_taf1-ts2Durant06 -0.65 0.223 92CIN5_H2O2Hi WT_V71E Chitikila_02 -0.65 0.2232 69NRG1_H2O2Hiisw2_sin3_vs._sin3Fazzio01 -0.65 0.2232 123HSF1_H2O2Lotaf1-ts2_spt3_E240KHuisinga04 0.65 0.2233 86FKH2_YPD ubp10sir4 Orlandi04 -0.65 0.2235 85AFT2_H2O2Lo WT Durant06 -0.65 0.2236 90HAP1_YPD DT_V71R Chitikila_02 -0.65 0.2236 140CBF1_SM spt10_del Xu05 -0.65 0.2237 271STE12_BUT14 Dsds3 Keogh05 -0.65 0.2238 117MCM1_Alpha Drpd3 Keogh05 0.64 0.2239 99

NDD1_YPD DT_V161R_L Chitikila_02 -0.64 0.2241 80REB1_YPD YAF9 Krogan04 0.64 0.2242 138MBP1_H2O2LoEAF7 Krogan04 0.64 0.2242 54ASH1_BUT14 sas3D Durant06 -0.64 0.2244 40STE12_BUT90 swi1_rich_medium_experimentSudarsanam00 -0.64 0.2244 77GCN4_SM htz1_hmr Meneghini03 0.64 0.2245 181MSN2_H2O2Hihos3_del Bernstein_00_affydeletions0.64 0.2245 69YAP7_H2O2Lo WT_V71E Chitikila_02 -0.64 0.2245 138YAP7_H2O2Lo sin3 Fazzio01 -0.64 0.2246 148SWI5_YPD ume6_del Bernstein_00_affydeletions0.64 0.2247 88CIN5_H2O2Hi spt3_E240K Huisinga04 -0.64 0.2247 69ACE2_YPD swr1_del Mizuguch04 0.64 0.2247 80MSN2_H2O2Hiubp10sir4 Orlandi04 0.64 0.2249 54HSF1_H2O2Lohht2K9131823GMartin04 0.64 0.2249 82SOK2_BUT14 SIR3 Hughes00 0.64 0.2249 72OAF1_YPD hat2_vs._YPH250Rosaleny05 -0.64 0.2249 53MSN4_RAPA spt10 Eriksson05 -0.64 0.225 54HSF1_H2O2Hi RAD6_haploid Hughes00 0.64 0.225 123SKN7_H2O2Losas3D Durant06 0.64 0.2251 149NRG1_YPD ARP4 Mnaimneh_04 0.64 0.2252 72YAP6_H2O2Hi ARP4 Mnaimneh_04 0.64 0.2253 79RCS1_H2O2LoIOC4 Hughes00 -0.64 0.2253 255PHD1_BUT90 arp8 Attikum04 0.64 0.2255 76PHO4_YPD MOT1-42 Dasgupta02 -0.64 0.2256 71DIG1_Alpha EAF7 Krogan04 -0.64 0.2256 57DAL82_RAPA delta_ssd1 Kaeberlein04 0.64 0.2258 56YAP6_H2O2Lo WT_V161E Chitikila_02 -0.64 0.2258 53SKN7_H2O2LoWT_Null_L Chitikila_02 0.64 0.226 175HAP4_YPD HAT2 Hughes00 0.64 0.226 66PHD1_YPD ubp10 Orlandi04 0.64 0.2263 33TYE7_YPD DT_Null Chitikila_02 -0.64 0.2264 53MCM1_YPD MED2_haploid Hughes00 -0.64 0.2264 77RCS1_H2O2Hi isw2_rpd3 Fazzio01 -0.64 0.2265 50STE12_Alpha taf1-ts2_spt3_E240KHuisinga04 0.64 0.2265 103CIN5_H2O2Hi hda1_del Bernstein_00_affydeletions0.64 0.2266 69STE12_BUT90 swi1_minimal_medium_experimentSudarsanam00 -0.64 0.2266 77STP1_SM BUR6 Geisberg_01 -0.64 0.2267 63PHO4_YPD Set1_del Bernstein02 -0.64 0.2268 70SWI4_YPD ume6 Fazzio01 -0.64 0.2268 152SKN7_H2O2Hi spt10 Eriksson05 -0.64 0.2268 99STE12_YPD DT_V71R Chitikila_02 -0.64 0.2269 47CIN5_H2O2Lo RAD6_haploid Hughes00 -0.64 0.2269 125REB1_YPD ISW2 Hughes00 0.64 0.227 143MBP1_H2O2Lotaf1-ts2_GCN5Huisinga04 -0.64 0.2272 51RLM1_YPD WT_N69R Chitikila_02 -0.64 0.2273 50PHO4_YPD SPT3 Ingvarsdottir05 -0.64 0.2274 68MBP1_H2O2Hihat1D Durant06 0.64 0.2274 99ASH1_BUT14 snf2_rich_medium_experimentSudarsanam00 0.64 0.2274 49OAF1_YPD ZDS1 Hughes00 0.64 0.2274 56YAP1_YPD ISW1 Hughes00 -0.64 0.2275 72ABF1_YPD RPD3_haploid Hughes00 0.64 0.2276 263MGA1_YPD MOT1-14 Dasgupta02 -0.64 0.2278 59DIG1_BUT14 isw2_rpd3_vs._rpd3Fazzio01 0.64 0.2279 63

MCM1_YPD HST3 Hughes00 -0.64 0.2285 77REB1_H2O2Hi DT_V71R Chitikila_02 0.64 0.2286 56RTG3_RAPA IOC4 Hughes00 -0.64 0.2287 51MBP1_H2O2HiDpho23 Keogh05 0.64 0.2288 130SKN7_YPD hat1_vs.YPH250Rosaleny05 -0.64 0.2289 60OAF1_YPD hat1D Durant06 -0.64 0.229 42FKH1_YPD SWR1 Krogan04 0.63 0.2291 132SKN7_H2O2HiDsap30 Keogh05 -0.63 0.2292 95CIN5_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 0.63 0.2293 58HAP1_YPD Deaf3 Keogh05 0.63 0.2293 128YAP1_YPD MED2_haploid Hughes00 -0.63 0.2295 71GCR2_SM rpd3_del Sabet04 -0.63 0.2295 54CIN5_H2O2Lo _SWC2_(VPS72)Krogan04 -0.63 0.2295 115XBP1_H2O2Lo ISW2 Hughes00 -0.63 0.2297 67AFT2_H2O2Hi ARP4 Mnaimneh_04 0.63 0.2298 61STE12_BUT14 taf1-ts2_gcn5_KQLHuisinga04 0.63 0.2298 101CBF1_SM taf1-ts2_25C Huisinga04 0.63 0.23 259RIM101_H2O2LoEPL1 Mnaimneh_04 -0.63 0.23 54XBP1_H2O2Lo hat2_vs._hat1Rosaleny05 -0.63 0.2302 61YAP6_H2O2Lo ume6 Fazzio01 -0.63 0.2302 57FKH2_YPD taf1-ts2_25C Huisinga04 0.63 0.2302 105PHO4_YPD ZDS1 Hughes00 -0.63 0.2303 71DAL81_RAPA DT_V71E Chitikila_02 0.63 0.2303 94CIN5_H2O2Hi SAP30 Hughes00 0.63 0.2303 79UME6_H2O2HiDT_V161R_L Chitikila_02 0.63 0.2304 93DIG1_BUT14 EPL1 Mnaimneh_04 0.63 0.2304 63MBP1_YPD Drxt2 Keogh05 -0.63 0.2304 125PHO4_YPD rpd3_H4KQ_v_H4KQSabet04 0.63 0.2305 70UME6_YPD hos2_del Bernstein_00_affydeletions-0.63 0.2306 122NDD1_YPD DT_N69S Chitikila_02 0.63 0.2306 80CBF1_SM HTZ1 Krogan04 0.63 0.2307 254DAL81_RAPA taf1-ts2_spt3 Huisinga04 -0.63 0.2308 89HAP1_YPD htz1 Meneghini03 0.63 0.2308 133REB1_H2O2Hi esa1-414 Durant06 -0.63 0.2309 56HAP1_YPD Ddep1 Keogh05 0.63 0.231 129NRG1_YPD SWC6_(VPS71)Krogan04 0.63 0.231 59FKH2_H2O2Hi sas3D_taf1-ts2Durant06 0.63 0.2311 94SUM1_YPD SPT8 Ingvarsdottir05 -0.63 0.2312 50CIN5_H2O2Hi spt10 Eriksson05 0.63 0.2312 76PHD1_BUT90 hat1D Durant06 -0.63 0.2312 83YAP6_YPD EPL1 Mnaimneh_04 -0.63 0.2313 91DIG1_Alpha DT_N69S Chitikila_02 -0.63 0.2313 49ASH1_BUT14 Dume1 Keogh05 -0.63 0.2314 43MCM1_YPD WT_N69R Chitikila_02 0.63 0.2316 68DAL82_RAPA gcn5D Durant06 -0.63 0.2319 46CBF1_SM gcn5 Huisinga04 0.63 0.232 269UME6_H2O2HiUBP8 Hughes00 -0.63 0.232 99TYE7_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.63 0.2321 54DAL82_SM htz1 Meneghini03 0.63 0.2321 54PUT3_H2O2Lo H3KQ Sabet04 0.63 0.2321 85SKN7_YPD SGF11 Ingvarsdottir05 -0.63 0.2323 53ABF1_YPD Drxt1 Keogh05 0.63 0.2326 263HSF1_H2O2Hi DM_vs._YPH250Rosaleny05 0.63 0.2326 117

SKN7_H2O2Hi ume6 Fazzio01 -0.63 0.2326 95STE12_BUT90 Drpd3 Keogh05 0.63 0.2326 75RTG3_RAPA WT_V161R_L Chitikila_02 -0.63 0.2328 48DIG1_BUT14 MED2_haploid Hughes00 -0.63 0.233 61MCM1_YPD DT_V71R Chitikila_02 0.63 0.233 70GCN4_RAPA SGF11 Ingvarsdottir05 -0.63 0.2331 140GCN4_RAPA SAP30 Hughes00 0.63 0.2331 159SKN7_YPD SIN3 Hughes00 0.63 0.2334 65RPN4_H2O2LoWT_V161R_K Chitikila_02 -0.63 0.2334 94YAP6_H2O2Hi DT_V71E Chitikila_02 -0.63 0.2335 76ACE2_YPD swr1 Meneghini03 0.63 0.2335 64YAP1_YPD Dsds3 Keogh05 0.63 0.2336 65GCR2_SM WT_TAF1_SPT3Huisinga04 -0.63 0.2336 54DAL82_RAPA SPT8 Ingvarsdottir05 -0.63 0.2336 47MGA1_YPD spt10_del Xu05 -0.63 0.2336 62DIG1_BUT14 hat1D Durant06 0.63 0.2339 49MSN4_RAPA htz1_del Mizuguch04 0.63 0.234 54FKH1_YPD hat2_vs._YPH250Rosaleny05 -0.63 0.234 136ABF1_YPD Dsin3 Keogh05 -0.63 0.2342 221SWI6_YPD PCH1 Hughes00 -0.63 0.2342 152UME6_H2O2Hiisw2_c.i. Fazzio01 -0.63 0.2342 98GCR2_SM SWC6_(VPS71)Krogan04 0.63 0.2343 52MCM1_YPD Dume1 Keogh05 -0.63 0.2344 71DAL82_SM sin3 Fazzio01 -0.62 0.2346 50YAP1_YPD WT_V161E Chitikila_02 -0.62 0.2347 67GCR2_SM YAF9 Krogan04 0.62 0.2347 52GCN4_RAPA isw2_rpd3 Fazzio01 0.62 0.2347 155SUM1_YPD rsc30_null Angus-Hill_01 -0.62 0.2349 55RCS1_H2O2LoDrco1 Keogh05 0.62 0.2349 246ASH1_BUT14 Drxt1 Keogh05 -0.62 0.235 49OAF1_YPD htz1_sir2 Meneghini03 0.62 0.2351 59FKH1_YPD isw2 Fazzio01 -0.62 0.2352 139TYE7_YPD hat1_vs.YPH250Rosaleny05 -0.62 0.2353 52REB1_H2O2Hi isw2_rpd3 Fazzio01 0.62 0.2354 56MCM1_YPD hht2_K27G Martin04 -0.62 0.2354 58RTG3_RAPA hht2_K27G Martin04 0.62 0.2355 43FKH2_H2O2Hi YNG2 Krogan04 0.62 0.2357 102DAL82_SM WT_V161R_L Chitikila_02 -0.62 0.236 50DIG1_Alpha SPT8 Ingvarsdottir05 -0.62 0.236 57SOK2_BUT14 elp3D Durant06 -0.62 0.2362 54ROX1_YPD rpd3_H4KQ_v_H4KQSabet04 -0.62 0.2363 58SUM1_YPD taf1-ts2_gcn5_KQLHuisinga04 0.62 0.2365 46SUT1_YPD taf1-ts2_SPT3 Huisinga04 0.62 0.2365 64YAP7_H2O2Lo SIR1 Hughes00 0.62 0.2366 151UME6_YPD DT_V161R_K Chitikila_02 0.62 0.2367 122DAL82_RAPA WT Durant06 -0.62 0.2367 53STE12_BUT90 rpd3_H3dN_v_H3dNSabet04 -0.62 0.2367 74UME6_YPD spt10 Eriksson05 0.62 0.2369 131TYE7_YPD htz1_sir2 Meneghini03 0.62 0.237 54NRG1_H2O2Hisir4 Orlandi04 -0.62 0.237 72MBP1_H2O2LoWT_Null_K Chitikila_02 0.62 0.2371 56MBP1_YPD ZDS1 Hughes00 0.62 0.2371 128HSF1_H2O2LoWT_V161R_L Chitikila_02 -0.62 0.2373 99

UME6_YPD WT_Null_K Chitikila_02 0.62 0.2374 120ROX1_YPD IES6 Hughes00 0.62 0.2375 67ASH1_BUT14 ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.62 0.2375 35STE12_BUT90 PCH1 Hughes00 -0.62 0.2375 77MBP1_YPD MOT1-42 Dasgupta02 -0.62 0.2375 129NDD1_YPD DM_vs._YPH250Rosaleny05 0.62 0.2376 77STE12_BUT14 IOC4 Hughes00 -0.62 0.2377 127ABF1_YPD htz1 Meneghini03 -0.62 0.2378 261NRG1_H2O2HiDsds3 Keogh05 -0.62 0.2378 116DIG1_Alpha ino80 Attikum04 -0.62 0.2379 42NDD1_YPD UBP8 Hughes00 0.62 0.238 83MBP1_H2O2LoWT Durant06 0.62 0.2383 54SWI5_YPD set1 Boa03 0.62 0.2386 99CBF1_SM hht2K9131823GMartin04 -0.62 0.2388 231PUT3_H2O2Lo MOT1-42 Dasgupta02 -0.62 0.2389 88XBP1_H2O2Lo YAF9 Krogan04 0.62 0.2389 64NRG1_H2O2Higcn5_KQL Huisinga04 0.62 0.2391 111REB1_H2O2Hi RPD3_haploid Hughes00 -0.62 0.2391 57HAP1_YPD spt3_E240K Huisinga04 0.62 0.2391 127CIN5_H2O2Hi HAT2 Hughes00 -0.62 0.2392 77STP1_SM SWD2 Mnaimneh_04 0.62 0.2395 68RPN4_H2O2LoWT_WT Chitikila_02 0.62 0.2397 94RPN4_H2O2Lorpd3_H3dN_v_H3dNSabet04 0.62 0.2397 98YAP7_H2O2Hi hos2_del Bernstein_00_affydeletions-0.62 0.2398 136ROX1_YPD hat2_vs._YPH250Rosaleny05 0.61 0.24 64ROX1_YPD htz1 Meneghini03 -0.61 0.24 66TYE7_YPD YNG2 Mnaimneh_04 -0.61 0.2401 56GLN3_RAPA gcn5D_taf1-ts2Durant06 0.61 0.2401 63GLN3_RAPA DT_V71E Chitikila_02 -0.61 0.2401 66CIN5_H2O2Hi WT_V161R_K Chitikila_02 0.61 0.2401 76YAP6_H2O2Lo DT_V71E Chitikila_02 -0.61 0.2401 54MSN4_RAPA spt3_E240K Huisinga04 0.61 0.2402 51MGA1_YPD arp8 Attikum04 0.61 0.2402 46NRG1_YPD elp3D Durant06 -0.61 0.2403 51MCM1_Alpha Dsap30 Keogh05 0.61 0.2404 104MGA1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 0.61 0.2404 48GLN3_RAPA SSD1-V Kaeberlein04 0.61 0.2406 67GCN4_SM rpd3_H4KQ_v_H4KQSabet04 0.61 0.2409 185SKN7_H2O2HiARD1 Hughes00 -0.61 0.2409 97CIN5_YPD WT_TAF1_SPT3Huisinga04 -0.61 0.241 142HSF1_H2O2LoISW1_ISW2 Hughes00 0.61 0.241 100SKN7_H2O2HiDsds3 Keogh05 0.61 0.2411 94ASH1_BUT14 rsc3-2 Angus-Hill_01 0.61 0.2411 49MSN4_H2O2HiSPT8 Ingvarsdottir05 0.61 0.2412 66TYE7_YPD spt10 Eriksson05 -0.61 0.2413 56YAP1_YPD spt3_E240K Huisinga04 0.61 0.2414 61STE12_BUT90 isw2_sin3 Fazzio01 -0.61 0.2415 77PUT3_H2O2Lo htz1 Meneghini03 -0.61 0.2418 84MCM1_Alpha WT_Null_K Chitikila_02 -0.61 0.2418 102UME6_H2O2HiWT_V161E Chitikila_02 -0.61 0.2419 90YAP7_H2O2Lo sap30_del Bernstein_00_affydeletions0.61 0.242 144DIG1_BUT14 HDA1 Hughes00 -0.61 0.242 63RIM101_H2O2LoSAP30 Hughes00 -0.61 0.2421 53

HAP1_YPD Drpd3 Keogh05 0.61 0.2421 126FKH2_YPD DT_Null Chitikila_02 0.61 0.2422 115MSN4_RAPA DT_V71R Chitikila_02 0.61 0.2425 51SUM1_YPD MOT1-42 Dasgupta02 0.61 0.2428 58UME6_YPD HDA1 Hughes00 0.61 0.2432 130CIN5_H2O2Hi WT_WT Chitikila_02 0.61 0.2432 78SWI5_YPD elp3D Durant06 -0.61 0.2433 84DAL82_SM taf1-ts2_spt3_E240KHuisinga04 0.61 0.2433 53MSN4_RAPA taf1-ts2_25C Huisinga04 0.61 0.2433 49FKH1_YPD hat2_vs._hat1Rosaleny05 -0.61 0.2436 136YAP6_YPD SWC6_(VPS71)Krogan04 -0.61 0.2438 82SWI5_YPD ARD1 Hughes00 -0.61 0.2439 101RTG3_RAPA taf1-ts2_gcn5_KQLHuisinga04 0.61 0.2441 47SWI5_YPD SIR1 Hughes00 0.61 0.2442 98HAP1_YPD WT_WT Chitikila_02 0.61 0.2442 138YAP1_YPD swi1_rich_medium_experimentSudarsanam00 0.61 0.2444 71RPN4_H2O2LoISW1_ISW2 Hughes00 -0.61 0.2445 99MSN2_H2O2HiWT_N69S Chitikila_02 -0.61 0.2446 74REB1_H2O2Hi swr1 Meneghini03 -0.61 0.2446 49MSN4_RAPA hht2_K27G Martin04 0.61 0.2447 35XBP1_H2O2Lo Ddep1 Keogh05 0.61 0.2447 66DAL82_SM SIR1 Hughes00 0.61 0.2448 54ABF1_YPD Deaf3 Keogh05 -0.61 0.2449 247CIN5_YPD VID21 Krogan04 0.61 0.2449 138ASH1_BUT14 hmr Meneghini03 -0.61 0.2449 47RPN4_H2O2Lotaf1-ts2_25C Huisinga04 0.61 0.245 92SKN7_H2O2Losnf2_rich_medium_experimentSudarsanam00 -0.61 0.245 185SUT1_YPD hmr Meneghini03 -0.61 0.2452 65GCR2_SM Dume1 Keogh05 0.61 0.2452 49YAP7_H2O2Lo DT_WT Chitikila_02 0.61 0.2453 145RCS1_H2O2Hi ume6 Fazzio01 0.6 0.2455 50XBP1_H2O2Lo DT_Null Chitikila_02 0.6 0.2458 66REB1_YPD taf1-ts2_spt3_E240KHuisinga04 0.6 0.246 134YAP1_YPD taf1-ts2 Durant06 0.6 0.246 71MSN4_H2O2Hihat1D Durant06 0.6 0.246 55PHO4_YPD Drxt1 Keogh05 -0.6 0.2462 72FKH2_H2O2Hi DT_V161R_K Chitikila_02 -0.6 0.2462 101STE12_BUT90 swr1 Meneghini03 0.6 0.2464 63MGA1_YPD WT_V71E Chitikila_02 0.6 0.2465 54UME6_H2O2HiSIR4 Hughes00 -0.6 0.2467 101MSN2_H2O2HiMED2_haploid Hughes00 -0.6 0.247 77NDD1_YPD SIR4 Hughes00 -0.6 0.247 85DAL82_RAPA ino80 Attikum04 0.6 0.2471 43YAP6_H2O2Lo taf1-ts2_25C Huisinga04 -0.6 0.2471 53GCN4_SM htz1 Meneghini03 0.6 0.2474 181CIN5_H2O2Lo snf2_minimal_medium_experimentSudarsanam00 -0.6 0.2474 127MCM1_Alpha Dume1 Keogh05 -0.6 0.2474 98MSN4_RAPA HDA1 Hughes00 -0.6 0.2475 54MGA1_YPD WT_Null_K Chitikila_02 0.6 0.2475 54REB1_YPD Dume1 Keogh05 0.6 0.2476 132SKN7_YPD DT_V71E Chitikila_02 0.6 0.2476 65SUT1_YPD swi1_rich_medium_experimentSudarsanam00 0.6 0.2476 69GCR2_SM ino80 Attikum04 -0.6 0.2477 43

RCS1_H2O2Hi isw2_ume6 Fazzio01 0.6 0.2478 50GLN3_RAPA HST3 Hughes00 0.6 0.2479 67DIG1_Alpha arp8_+_0.1%_MMS_vs._arp8Attikum04 0.6 0.2479 43DAL82_SM Ddep1 Keogh05 0.6 0.2481 50MSN2_H2O2Hiisw2_c.i. Fazzio01 -0.6 0.2481 74RCS1_H2O2Lotaf1-ts2_gcn5_KQLHuisinga04 -0.6 0.2481 235PHD1_BUT90 SWR1 Krogan04 -0.6 0.2481 101CIN5_YPD EAF7 Krogan04 0.6 0.2482 136RTG3_RAPA rpd3_H3dN_v_H3dNSabet04 -0.6 0.2482 50RIM101_H2O2LoH4KQ Sabet04 0.6 0.2483 44PHD1_BUT90 set1 Boa03 0.6 0.2483 106GCN4_RAPA DT_V161R_K Chitikila_02 -0.6 0.2484 155AFT2_H2O2Lo sap30_del Bernstein_00_affydeletions0.6 0.2484 85STP1_SM htz1 Meneghini03 0.6 0.2485 65STE12_Alpha arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.6 0.2485 87OAF1_YPD ARD1 Hughes00 -0.6 0.2486 59PUT3_H2O2Lo YAF9 Krogan04 0.6 0.2487 80STE12_Alpha hht2_K4G Martin04 -0.6 0.2489 90FKH2_H2O2Hi SPT8 Ingvarsdottir05 -0.6 0.249 98YAP1_YPD SIR1 Hughes00 0.6 0.2491 72PHD1_BUT90 WT Durant06 -0.6 0.2492 105FKH2_YPD hht2_K4914182327GMartin04 0.6 0.2492 100ROX1_YPD hos2_del Bernstein_00_affydeletions-0.6 0.2493 53FKH1_YPD elp3D_taf1-ts2Durant06 -0.6 0.2493 118YAP6_H2O2Lo 0.1%_MMS Attikum04 -0.6 0.2494 40YAP7_H2O2Lo taf1-ts2_spt3_E240KHuisinga04 0.6 0.2494 142SWI5_YPD WT_TAF1_GCN5Huisinga04 0.6 0.2497 97CIN5_H2O2Lo hpa2D_taf1-ts2Durant06 0.6 0.2497 88OAF1_YPD TAF2 Mnaimneh_04 0.6 0.2498 59GLN3_RAPA RAD6_haploid Hughes00 0.6 0.25 67MSN4_H2O2HiEAF7 Krogan04 0.6 0.2501 64NRG1_H2O2Hihat1_vs.YPH250Rosaleny05 -0.6 0.2501 111MBP1_H2O2LoHST3 Hughes00 -0.6 0.2501 57SKN7_H2O2Lohht2_K4G Martin04 0.6 0.2502 146PHD1_YPD SIR4 Hughes00 0.6 0.2503 67PHD1_BUT90 hat2_vs._hat1Rosaleny05 0.6 0.2503 97FKH2_H2O2Hi htz1_sir2 Meneghini03 0.6 0.2504 105YAP7_H2O2Lo ubp10sir4 Orlandi04 -0.6 0.2504 101MCM1_YPD ubp10 Orlandi04 -0.6 0.2504 52PHO4_YPD Hda1_del Bernstein02 -0.6 0.2508 70SKN7_H2O2HiSAP30 Hughes00 -0.6 0.2508 97AFT2_H2O2Lo WT_Null_K Chitikila_02 -0.6 0.2508 95DIG1_Alpha Dsds3 Keogh05 -0.6 0.2508 58MBP1_YPD Drco1 Keogh05 0.6 0.2508 125STE12_YPD IOC4 Hughes00 -0.6 0.2511 54MSN2_H2O2HiDT_WT Chitikila_02 0.6 0.2511 75SKN7_YPD H3_1-28 Sabet04 -0.59 0.2512 62DIG1_BUT14 hpa2D Durant06 -0.59 0.2512 51GLN3_RAPA rpd3_H3dN_v_H3dNSabet04 -0.59 0.2513 66SUM1_YPD hat2_vs._hat1Rosaleny05 0.59 0.2514 52RIM101_H2O2LoH3KQ Sabet04 0.59 0.2515 44AFT2_H2O2Lo Dsds3 Keogh05 0.59 0.2517 89UME6_H2O2HiIOC4 Hughes00 0.59 0.2518 100

FKH2_H2O2Hi DT_V161R_L Chitikila_02 -0.59 0.2519 98FKH2_YPD rsc30_null Angus-Hill_01 0.59 0.252 113MSN4_RAPA MOT1-14 Dasgupta02 0.59 0.2522 52HAP1_YPD H4_2-26 Sabet04 -0.59 0.2523 137HAP4_YPD SIR3 Hughes00 0.59 0.2523 67DIG1_Alpha sas3D_taf1-ts2Durant06 0.59 0.2524 51CIN5_H2O2Lo Ddep1 Keogh05 -0.59 0.2525 115SKN7_YPD htz1 Meneghini03 0.59 0.2526 66PHD1_BUT90 isw2_sin3_vs._sin3Fazzio01 -0.59 0.2527 103FKH2_YPD ubp10 Orlandi04 -0.59 0.2527 78RIM101_H2O2Lotaf1-ts2_spt3 Huisinga04 -0.59 0.2528 49HAP4_YPD rpd3_del Sabet04 -0.59 0.2528 62DAL82_RAPA WT_TAF1_SPT3Huisinga04 -0.59 0.2529 52CIN5_YPD SIN3 Hughes00 0.59 0.253 148PHD1_YPD YNG2 Krogan04 -0.59 0.2531 64DAL81_RAPA ISW1_ISW2 Hughes00 0.59 0.2531 95XBP1_H2O2Lo gcn5_KQL Huisinga04 -0.59 0.2531 56DIG1_BUT14 MOT1-42 Dasgupta02 -0.59 0.2534 63DIG1_BUT14 WT_V161E Chitikila_02 0.59 0.2534 59AFT2_H2O2Hi PCH1 Hughes00 0.59 0.254 60NRG1_YPD htz1_sir2 Meneghini03 -0.59 0.2541 71STP1_SM ZDS1 Hughes00 0.59 0.2542 67CBF1_SM hda1_del Bernstein_00_affydeletions0.59 0.2545 266SOK2_BUT14 swr1_del Mizuguch04 -0.59 0.2546 72YAP7_H2O2Hi hos3_del Bernstein_00_affydeletions0.59 0.2547 136GLN3_RAPA DT_N69R Chitikila_02 0.59 0.2548 64SUT1_YPD Drco1 Keogh05 0.59 0.255 62GCR2_SM RPD3_haploid Hughes00 -0.59 0.255 54HAP1_YPD HIR2 Hughes00 0.59 0.2551 138MCM1_YPD spt3_E240K Huisinga04 0.59 0.2552 71MGA1_YPD htz1_del Mizuguch04 -0.59 0.2552 62FKH1_YPD sap30_del Bernstein_00_affydeletions0.59 0.2553 134SOK2_BUT14 elp3D_taf1-ts2Durant06 0.59 0.2553 47DAL82_RAPA hat1D Durant06 -0.59 0.2554 37CIN5_H2O2Hi hht2_K4G Martin04 -0.59 0.2554 54MSN4_RAPA EPL1 Mnaimneh_04 -0.59 0.2555 54MCM1_YPD gcn5 Huisinga04 0.59 0.2557 73DAL82_SM ubp10sir4 Orlandi04 -0.59 0.2558 37SOK2_BUT14 spt10 Eriksson05 0.59 0.2559 67GCN4_SM hpa2D Durant06 0.59 0.2561 159RPN4_H2O2Loume6 Fazzio01 0.59 0.2562 97YAP6_H2O2Lo isw2_sin3_vs._sin3Fazzio01 -0.59 0.2563 57YAP7_H2O2Lo hat2_vs._YPH250Rosaleny05 0.59 0.2563 147UME6_H2O2HiSIR1 Hughes00 -0.59 0.2564 100RIM101_H2O2Losnf2_rich_medium_experimentSudarsanam00 0.59 0.2568 54DIG1_Alpha rsc3-2 Angus-Hill_01 0.59 0.2569 57XBP1_H2O2Lo ume6_del Bernstein_00_affydeletions0.58 0.2571 54UME6_H2O2HiPCH1 Hughes00 -0.58 0.2572 101OAF1_YPD ume6 Fazzio01 0.58 0.2573 56DAL82_SM SIR4 Hughes00 0.58 0.2574 55FKH1_YPD hht2_K914182327GMartin04 0.58 0.2574 122STE12_BUT14 ubp10sir4 Orlandi04 -0.58 0.2575 81ACE2_YPD DT_Null Chitikila_02 0.58 0.2575 77

OAF1_YPD RAD6_haploid Hughes00 0.58 0.2575 58AFT2_H2O2Lo DT_V161R_L Chitikila_02 0.58 0.2576 95RLM1_YPD RPD3_haploid Hughes00 -0.58 0.2578 52YAP7_H2O2Hi SIR1 Hughes00 0.58 0.2579 140YAP7_H2O2Lo TAF2 Mnaimneh_04 -0.58 0.2579 151FKH2_H2O2Hi rpd3_del Sabet04 0.58 0.2581 103UME6_H2O2HiVID21 Krogan04 -0.58 0.2581 83YAP7_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 0.58 0.2584 128RPN4_H2O2Loino80_del Mizuguch04 -0.58 0.2584 100YAP6_H2O2Lo SIR4 Hughes00 -0.58 0.2585 58STE12_Alpha ISW2 Hughes00 -0.58 0.2585 115RIM101_H2O2Losin3_del Bernstein_00_affydeletions-0.58 0.2586 39PHD1_BUT90 ubp10 Orlandi04 0.58 0.2586 61MSN4_RAPA H4_2-26 Sabet04 -0.58 0.2587 52SUT1_YPD WT_TAF1_GCN5Huisinga04 0.58 0.2588 68STE12_BUT14 SGF11 Ingvarsdottir05 -0.58 0.2589 109GCN4_SM set1 Boa03 0.58 0.2591 187HSF1_H2O2LoDsap30 Keogh05 0.58 0.2591 95FKH1_YPD SPT3 Ingvarsdottir05 0.58 0.2592 127FKH1_YPD EPL1 Mnaimneh_04 -0.58 0.2592 142PHO4_YPD hpa2D_taf1-ts2Durant06 -0.58 0.2594 55SUT1_YPD gcn5_KQL Huisinga04 0.58 0.2594 61SUT1_YPD H4KQ Sabet04 0.58 0.2595 66HSF1_H2O2Hi SGF11 Ingvarsdottir05 0.58 0.2596 104DIG1_Alpha delta_ssd1 Kaeberlein04 -0.58 0.2596 59AFT2_H2O2Lo taf1-ts2_spt3 Huisinga04 0.58 0.2598 93SKN7_H2O2LoDT_N69R Chitikila_02 -0.58 0.26 170YAP6_H2O2Lo MED2_haploid Hughes00 0.58 0.26 58YAP7_H2O2Lo hat1D_taf1-ts2Durant06 0.58 0.26 127FKH1_YPD DT_V161R_K Chitikila_02 -0.58 0.26 136CIN5_H2O2Lo rsc3-2 Angus-Hill_01 0.58 0.2601 127SUM1_YPD EAF7 Krogan04 -0.58 0.2602 52DAL81_RAPA SPT8 Ingvarsdottir05 0.58 0.2602 82MBP1_H2O2HiDsin3 Keogh05 0.58 0.2602 105UME6_H2O2Hiarp8_+_0.1%_MMS_vs._arp8Attikum04 0.58 0.2603 74DIG1_Alpha HIR2 Hughes00 -0.58 0.2604 58REB1_H2O2Hi DT_V161R_K Chitikila_02 0.58 0.2606 58ASH1_BUT14 isw2_sin3 Fazzio01 0.58 0.2607 49STE12_YPD HST3 Hughes00 -0.58 0.2608 52HAP1_YPD HDA1 Hughes00 -0.58 0.2608 141PUT3_H2O2Lo Deaf3 Keogh05 0.58 0.2609 79UME6_H2O2HiHAT2 Hughes00 -0.58 0.2611 99AFT2_H2O2Lo taf1-ts2_GCN5Huisinga04 0.58 0.2613 92FKH2_H2O2Hi VID21 Krogan04 0.58 0.2614 97MBP1_H2O2Hiume6_del Bernstein_00_affydeletions-0.58 0.2614 126XBP1_H2O2Lo SPT8 Ingvarsdottir05 -0.58 0.2614 64REB1_H2O2Hi ume6_del Bernstein_00_affydeletions-0.58 0.2615 56NRG1_YPD WT_F182V Chitikila_02 -0.58 0.2615 54AFT2_H2O2Lo DM_vs._YPH250Rosaleny05 0.58 0.2616 81DIG1_BUT14 UBP8 Hughes00 0.58 0.2616 63STE12_BUT90 ISW1_ISW2 Hughes00 -0.58 0.2617 78CBF1_SM isw2_rpd3 Fazzio01 0.58 0.2618 270ABF1_YPD ZDS1 Hughes00 -0.58 0.2619 262

REB1_YPD MOT1-42 Dasgupta02 -0.58 0.2621 140HSF1_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 -0.58 0.2621 119XBP1_H2O2Lo PCH1 Hughes00 -0.58 0.2622 67TYE7_YPD taf1-ts2_gcn5 Huisinga04 -0.58 0.2623 50CIN5_H2O2Lo hht2_K4G Martin04 -0.58 0.2623 87GCN4_YPD WT_N69S Chitikila_02 -0.58 0.2623 71MGA1_YPD rpd3_c.i. Fazzio01 -0.58 0.2623 60REB1_H2O2Hi Hda1_del Bernstein02 -0.58 0.2625 57STE12_BUT90 rsc30_null Angus-Hill_01 -0.58 0.2625 71ROX1_YPD Rpd3_del Bernstein02 -0.58 0.2626 67NDD1_YPD isw2 Fazzio01 0.58 0.2626 80STP1_SM ISW1_ISW2 Hughes00 -0.58 0.2629 67YAP6_H2O2Hi DT_Null Chitikila_02 0.58 0.2629 77FKH2_YPD htz1_del Mizuguch04 0.57 0.2632 120RPN4_H2O2LoSWR1 Krogan04 -0.57 0.2633 99MBP1_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 -0.57 0.2634 128STE12_BUT90 taf1-ts2_gcn5 Huisinga04 0.57 0.2634 73NDD1_YPD taf1-ts2_SPT3 Huisinga04 0.57 0.2634 82TYE7_YPD sin3_del Bernstein_00_affydeletions0.57 0.2635 55RTG3_RAPA hda1_del Bernstein_00_affydeletions0.57 0.2635 48XBP1_H2O2Lo Drpd3 Keogh05 -0.57 0.2635 64MGA1_YPD DT_V71E Chitikila_02 -0.57 0.2638 58SWI5_YPD Set1_del Bernstein02 -0.57 0.2639 100MGA1_YPD DT_V161R_K Chitikila_02 0.57 0.264 59ABF1_YPD swr1_del Mizuguch04 0.57 0.2643 267TYE7_YPD MED2_haploid Hughes00 0.57 0.2643 55RIM101_H2O2LoDsds3 Keogh05 -0.57 0.2643 48PHD1_BUT90 YAF9 Krogan04 0.57 0.2644 98REB1_H2O2Hi hat1D Durant06 0.57 0.2645 46PHO4_YPD Drxt2 Keogh05 -0.57 0.2648 66DAL82_SM WT_V71R Chitikila_02 -0.57 0.2648 52SOK2_BUT14 taf1-ts2_spt3_E240KHuisinga04 -0.57 0.2648 61MGA1_YPD isw2_ume6 Fazzio01 -0.57 0.2649 60GLN3_RAPA delta_ssd1 Kaeberlein04 0.57 0.265 67NRG1_H2O2Hiswr1_del Mizuguch04 0.57 0.265 126MBP1_H2O2Loswi1_rich_medium_experimentSudarsanam00 0.57 0.265 57XBP1_H2O2Lo H3_1-28 Sabet04 -0.57 0.265 55STE12_BUT90 spt10_del Xu05 0.57 0.265 76UME6_H2O2Hihat2_vs._YPH250Rosaleny05 0.57 0.2652 95PUT3_H2O2Lo WT_V71E Chitikila_02 0.57 0.2652 71ASH1_BUT14 Dsds3 Keogh05 0.57 0.2652 45SUT1_YPD H3_1-28 Sabet04 0.57 0.2654 66DIG1_Alpha SIR3 Hughes00 -0.57 0.2655 59MBP1_YPD snf2_minimal_medium_experimentSudarsanam00 -0.57 0.2655 130REB1_YPD WT_V71R Chitikila_02 -0.57 0.2658 127GCN4_RAPA isw2_c.i. Fazzio01 -0.57 0.2659 155MBP1_YPD SWD2 Mnaimneh_04 -0.57 0.2661 130ASH1_BUT14 TUP1_haploid Hughes00 0.57 0.2662 50SWI6_YPD Dume1 Keogh05 -0.57 0.2665 143RTG3_RAPA Drpd3 Keogh05 0.57 0.2665 47ACE2_YPD RSC8 Mnaimneh_04 0.57 0.2665 80GCN4_SM H3_1-28 Sabet04 0.57 0.2666 184CIN5_H2O2Hi sap30_del Bernstein_00_affydeletions-0.57 0.2666 68

ROX1_YPD ISW2 Hughes00 -0.57 0.2668 67MSN2_H2O2Hiume6_del Bernstein_00_affydeletions0.57 0.2669 71DAL81_RAPA SWR1 Krogan04 0.57 0.267 89AFT2_H2O2Lo DT_N69R Chitikila_02 0.57 0.267 91YAP1_YPD htz1_hmr Meneghini03 -0.57 0.2672 67RCS1_H2O2Losnf2_rich_medium_experimentSudarsanam00 -0.57 0.2672 256PHO4_YPD EPL1 Mnaimneh_04 -0.57 0.2673 72SKN7_YPD sir2 Meneghini03 -0.57 0.2673 65XBP1_H2O2Lo Dume1 Keogh05 -0.57 0.2673 64OAF1_YPD DT_V161R_L Chitikila_02 -0.57 0.2675 52YAP1_YPD sap30_del Bernstein_00_affydeletions0.57 0.2676 67STE12_Alpha hat2_vs._hat1Rosaleny05 0.57 0.2676 110STE12_BUT90 WT_TAF1_GCN5Huisinga04 0.57 0.2677 77ASH1_BUT14 SIN3 Hughes00 0.57 0.2678 49UME6_YPD isw2_sin3_vs._sin3Fazzio01 0.57 0.2679 125CIN5_H2O2Lo EPL1 Mnaimneh_04 0.57 0.2679 127NDD1_YPD isw2_ume6 Fazzio01 -0.57 0.2679 80SWI5_YPD EAF5 Krogan04 0.57 0.268 91RIM101_H2O2LoDsap30 Keogh05 -0.57 0.268 53SWI5_YPD TUP1_haploid Hughes00 0.57 0.2682 99SKN7_H2O2Hi hos2_del Bernstein_00_affydeletions-0.57 0.2683 85CIN5_YPD Rpd3_del Bernstein02 -0.57 0.2685 149RTG3_RAPA Dpho23 Keogh05 0.57 0.2685 52RCS1_H2O2Hi hat2_vs._YPH250Rosaleny05 0.57 0.2685 50ROX1_YPD H3KQ Sabet04 0.57 0.2687 58MSN4_H2O2Hihht2_K4914182327GMartin04 0.57 0.2687 63ASH1_BUT14 hat2_vs._YPH250Rosaleny05 -0.57 0.2687 46MBP1_YPD sas3D_taf1-ts2Durant06 -0.57 0.2688 121GCN4_SM sas3D Durant06 -0.56 0.2693 158REB1_H2O2Hi TAF2 Mnaimneh_04 0.56 0.2693 59CBF1_SM WT_WT Chitikila_02 -0.56 0.2695 265FKH2_YPD sir2 Meneghini03 -0.56 0.2695 119SWI6_YPD rsc3-2 Angus-Hill_01 -0.56 0.2696 151FKH2_H2O2Hi Drxt1 Keogh05 0.56 0.2699 104XBP1_H2O2Lo SWD2 Mnaimneh_04 0.56 0.2699 68MBP1_H2O2Loswr1_del Mizuguch04 0.56 0.2701 56PHO4_YPD ISW2 Hughes00 0.56 0.2702 71STP1_SM rpd3_c.i. Fazzio01 0.56 0.2704 67RCS1_H2O2Hi hht2_K49141823GMartin04 -0.56 0.2704 36STE12_BUT14 WT_V71R Chitikila_02 -0.56 0.2704 115RTG3_RAPA DM_vs._YPH250Rosaleny05 -0.56 0.2705 49RLM1_YPD taf1-ts2_spt3_E240KHuisinga04 -0.56 0.2706 46YAP1_YPD SIN3 Hughes00 0.56 0.2707 71TYE7_YPD DM_vs._YPH250Rosaleny05 0.56 0.2709 53YAP6_H2O2Lo sir4 Orlandi04 -0.56 0.2709 26NRG1_YPD ZDS1 Hughes00 0.56 0.2709 71SUT1_YPD ISW1 Hughes00 0.56 0.271 69YAP6_YPD hht2_K914182327GMartin04 0.56 0.2711 61GCN4_YPD WT_V161R_L Chitikila_02 -0.56 0.2712 74OAF1_YPD set1 Boa03 0.56 0.2713 58HSF1_H2O2Hi isw2_sin3 Fazzio01 -0.56 0.2717 119RCS1_H2O2Hi BUR6 Geisberg_01 0.56 0.2718 51UME6_H2O2Hihmr Meneghini03 0.56 0.2718 98

TYE7_YPD hht2K9131823GMartin04 0.56 0.2719 51CBF1_SM H3_1-28 Sabet04 -0.56 0.2719 272MBP1_H2O2HiDT_Null Chitikila_02 0.56 0.2719 125RCS1_H2O2Hi gcn5D Durant06 0.56 0.2719 45MSN4_RAPA SGF11 Ingvarsdottir05 0.56 0.2721 42RTG3_RAPA swi1_minimal_medium_experimentSudarsanam00 -0.56 0.2721 52NDD1_YPD H4_2-26 Sabet04 0.56 0.2721 83AFT2_H2O2Hi taf1-ts2_25C Huisinga04 -0.56 0.2723 57YAP7_H2O2Hi taf1-ts2_spt3 Huisinga04 0.56 0.2724 136RIM101_H2O2LoHTZ1 Krogan04 -0.56 0.2724 50YAP6_H2O2Hi H3KQ Sabet04 -0.56 0.2725 71FKH2_YPD SPT8 Ingvarsdottir05 -0.56 0.2725 108DAL82_RAPA RSC8 Mnaimneh_04 0.56 0.2728 56REB1_YPD sas3D_taf1-ts2Durant06 -0.56 0.2731 127SKN7_YPD htz1_hmr Meneghini03 0.56 0.2731 65AFT2_H2O2Hi hat2_vs._hat1Rosaleny05 -0.56 0.2732 58RCS1_H2O2LoDT_V161R_L Chitikila_02 -0.56 0.2732 239YAP6_H2O2Lo hpa2D Durant06 -0.56 0.2737 43ACE2_YPD rsc30_null Angus-Hill_01 -0.56 0.2737 79SWI5_YPD DT_V161E Chitikila_02 -0.56 0.2738 92SWI5_YPD isw2_c.i._rpd3_c.i.Fazzio01 -0.56 0.274 94MBP1_YPD sir4 Orlandi04 -0.56 0.274 95DAL82_RAPA Hda1_del Bernstein02 0.56 0.2741 55RLM1_YPD delta_ssd1 Kaeberlein04 0.56 0.2742 52MSN4_RAPA HAT2 Hughes00 0.56 0.2742 54SWI5_YPD rsc3-2 Angus-Hill_01 -0.56 0.2745 98MSN4_RAPA delta_ssd1 Kaeberlein04 -0.56 0.2745 53SKN7_H2O2HiUBP8 Hughes00 0.56 0.2745 96UME6_YPD HIR2 Hughes00 0.56 0.2746 129MBP1_H2O2HiHST3 Hughes00 -0.56 0.2748 132YAP7_H2O2Hi isw2_sin3_vs._sin3Fazzio01 -0.56 0.2748 137STP1_SM hht2_K49141823GMartin04 -0.56 0.2749 51ACE2_YPD RPD3_haploid Hughes00 0.56 0.2749 79DIG1_Alpha VID21 Krogan04 0.56 0.275 46HAP4_YPD WT_TAF1_GCN5Huisinga04 -0.56 0.275 66RCS1_H2O2Hi snf2_rich_medium_experimentSudarsanam00 0.56 0.2751 52UME6_H2O2HiH3_1-28 Sabet04 0.56 0.2751 99PUT3_H2O2Lo EPL1 Mnaimneh_04 0.56 0.2751 88PHD1_BUT90 SPT3 Ingvarsdottir05 0.56 0.2751 96ACE2_YPD HST3 Hughes00 -0.56 0.2751 79MBP1_H2O2HiMOT1-14 Dasgupta02 -0.56 0.2752 131DAL82_RAPA sas3D_taf1-ts2Durant06 0.56 0.2753 45CIN5_H2O2Lo rpd3_del Sabet04 -0.56 0.2754 119HAP4_YPD taf1-ts2_gcn5 Huisinga04 -0.56 0.2754 64UME6_YPD taf1-ts2_spt3_E240KHuisinga04 0.55 0.2755 115FKH2_YPD taf1-ts2_SPT3 Huisinga04 -0.55 0.2757 116DIG1_Alpha HAT2 Hughes00 0.55 0.2759 60DIG1_BUT14 snf2_rich_medium_experimentSudarsanam00 -0.55 0.2759 63DIG1_Alpha arp8 Attikum04 -0.55 0.276 43MGA1_YPD SIR4 Hughes00 -0.55 0.276 61YAP1_YPD isw2_ume6 Fazzio01 0.55 0.2762 68MBP1_YPD Hda1_del Bernstein02 -0.55 0.2762 129PHO4_YPD BUR6 Geisberg_01 -0.55 0.2763 69

DIG1_Alpha WT_F182V Chitikila_02 0.55 0.2767 41STE12_BUT14 isw2_ume6 Fazzio01 -0.55 0.2769 127YAP7_H2O2Lo isw2_c.i. Fazzio01 -0.55 0.2771 148DIG1_Alpha Dsin3 Keogh05 -0.55 0.2771 45YAP7_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 -0.55 0.2772 141YAP7_H2O2Hi swr1 Meneghini03 0.55 0.2772 116MBP1_H2O2HiDrxt1 Keogh05 -0.55 0.2773 131OAF1_YPD ino80_del Mizuguch04 0.55 0.2774 59ASH1_BUT14 BUR6 Geisberg_01 0.55 0.2775 45FKH2_YPD DT_V161R_K Chitikila_02 -0.55 0.2777 118MCM1_YPD Set1_del Bernstein02 -0.55 0.2777 77MBP1_YPD set1 Boa03 -0.55 0.278 130SWI6_YPD hht2_K49141823GMartin04 0.55 0.2781 131UME6_YPD DM_vs._YPH250Rosaleny05 0.55 0.2785 121MSN4_RAPA DT_WT Chitikila_02 -0.55 0.2785 51SUM1_YPD hht2_K49141823GMartin04 0.55 0.2787 25ASH1_BUT14 HIR2 Hughes00 -0.55 0.2788 48YAP7_H2O2Hi hda1_del Bernstein_00_affydeletions0.55 0.279 136HSF1_H2O2Hi Dsin3 Keogh05 -0.55 0.2791 104CIN5_H2O2Lo HTZ1 Krogan04 -0.55 0.2792 119STE12_BUT90 spt10 Eriksson05 -0.55 0.2792 76DAL82_SM H3KQ Sabet04 -0.55 0.2793 50RTG3_RAPA ino80 Attikum04 0.55 0.2793 39YAP7_H2O2Lo EAF5 Krogan04 0.55 0.2793 136UME6_H2O2Hielp3D Durant06 0.55 0.2794 79SUM1_YPD _SWC2_(VPS72)Krogan04 0.55 0.2795 51SKN7_H2O2Hi isw2 Fazzio01 0.55 0.2795 95REB1_YPD HDA1 Hughes00 -0.55 0.2796 143YAP7_H2O2Lo swi1_rich_medium_experimentSudarsanam00 0.55 0.2796 150CIN5_H2O2Lo DT_V161R_K Chitikila_02 0.55 0.2797 124RPN4_H2O2LoDrpd3 Keogh05 -0.55 0.2797 92UME6_YPD H3_1-28 Sabet04 -0.55 0.28 129RCS1_H2O2Hi DT_Null Chitikila_02 -0.55 0.2803 49PHO4_YPD gcn5 Huisinga04 -0.55 0.2804 69DAL82_SM ume6 Fazzio01 -0.55 0.2804 49PHD1_YPD SIR3 Hughes00 0.55 0.2805 64YAP1_YPD hos2_del Bernstein_00_affydeletions-0.55 0.2805 68MCM1_YPD Ddep1 Keogh05 0.55 0.2806 72SUM1_YPD snf2_minimal_medium_experimentSudarsanam00 -0.55 0.2807 58YAP6_H2O2Lo rpd3_H3dN_v_H3dNSabet04 -0.55 0.2807 51YAP7_H2O2Lo SIR4 Hughes00 0.55 0.2807 152MCM1_Alpha H4KQ Sabet04 0.55 0.2807 103HSF1_H2O2Hi UBP8 Hughes00 0.55 0.2808 121MCM1_YPD SAP30 Hughes00 0.55 0.2808 77AFT2_H2O2Lo Drxt1 Keogh05 -0.55 0.2809 96DAL82_SM gcn5 Huisinga04 -0.55 0.281 53HSF1_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 0.55 0.2811 100DAL82_RAPA DT_V161R_K Chitikila_02 0.55 0.2814 55RTG3_RAPA WT_Null_K Chitikila_02 0.55 0.2815 50DAL82_RAPA htz1_hmr Meneghini03 0.55 0.2818 52GCN4_RAPA YAF9 Krogan04 -0.54 0.2821 155RPN4_H2O2LoSGF11 Ingvarsdottir05 0.54 0.2821 88SUT1_YPD EAF7 Krogan04 -0.54 0.2825 62

ACE2_YPD hat2_vs._hat1Rosaleny05 -0.54 0.2829 76PHD1_YPD set1 Boa03 0.54 0.2831 67RLM1_YPD WT_TAF1_SPT3Huisinga04 0.54 0.2832 53MSN4_H2O2HiDT_V161R_L Chitikila_02 -0.54 0.2832 69YAP7_H2O2Lo ume6_del Bernstein_00_affydeletions0.54 0.2834 146GLN3_RAPA SPT8 Ingvarsdottir05 0.54 0.2835 62HSF1_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 0.54 0.2835 105SWI6_YPD rpd3_H3dN_v_H3dNSabet04 0.54 0.2836 148MBP1_YPD sap30_del Bernstein_00_affydeletions0.54 0.2836 122GLN3_RAPA isw2 Fazzio01 -0.54 0.2837 67STE12_BUT90 ISW1 Hughes00 0.54 0.2838 77CBF1_SM isw2_rpd3_vs._rpd3Fazzio01 0.54 0.2839 271STE12_BUT14 hda1_del Bernstein_00_affydeletions-0.54 0.2839 120NRG1_H2O2HiSIR4 Hughes00 0.54 0.284 126UME6_H2O2Hisnf2_minimal_medium_experimentSudarsanam00 0.54 0.284 102STP1_SM ume6_del Bernstein_00_affydeletions-0.54 0.2842 64REB1_H2O2Hi hpa2D_taf1-ts2Durant06 0.54 0.2842 45ABF1_YPD sap30_del Bernstein_00_affydeletions0.54 0.2847 254FKH1_YPD H4KQ Sabet04 -0.54 0.2848 138TYE7_YPD YNG2 Krogan04 -0.54 0.2851 54GCN4_SM taf1-ts2_spt3_E240KHuisinga04 0.54 0.2853 177UME6_YPD swi1_rich_medium_experimentSudarsanam00 0.54 0.2855 131RIM101_H2O2LoSIR3 Hughes00 0.54 0.2855 53MBP1_YPD MED2_haploid Hughes00 0.54 0.2855 129STE12_Alpha taf1-ts2_25C Huisinga04 0.54 0.2856 105DAL82_SM hos3_del Bernstein_00_affydeletions-0.54 0.2857 48NRG1_H2O2Hihtz1_hmr Meneghini03 -0.54 0.2858 122RIM101_H2O2Lotaf1-ts2_gcn5 Huisinga04 0.54 0.286 49RIM101_H2O2Lospt10 Eriksson05 0.54 0.2861 46MGA1_YPD ubp10sir4 Orlandi04 0.54 0.2861 42RTG3_RAPA BUR6 Geisberg_01 0.54 0.2862 48MSN4_H2O2Hirpd3_c.i. Fazzio01 -0.54 0.2862 68YAP6_YPD Ddep1 Keogh05 -0.54 0.2867 87REB1_H2O2Hi HDA1 Hughes00 0.54 0.2867 57CIN5_YPD SWR1 Krogan04 -0.54 0.2869 136FKH1_YPD DT_N69R Chitikila_02 -0.54 0.2869 137SWI6_YPD SIR1 Hughes00 0.54 0.287 151FKH2_YPD Drxt2 Keogh05 0.54 0.2872 115HSF1_H2O2Hi SWD2 Mnaimneh_04 0.54 0.2874 123XBP1_H2O2Lo WT_TAF1_SPT3Huisinga04 0.54 0.2874 65ACE2_YPD taf1-ts2_spt3_E240KHuisinga04 0.54 0.2876 67FKH2_H2O2Hi sir4 Orlandi04 -0.54 0.2877 76UME6_H2O2HiWT_V71R Chitikila_02 0.54 0.2877 91SWI5_YPD isw2_ume6 Fazzio01 0.54 0.2878 94REB1_YPD taf1-ts2_SPT3 Huisinga04 0.54 0.2879 134DAL82_RAPA H3_1-28 Sabet04 -0.54 0.2879 53AFT2_H2O2Hi Dume1 Keogh05 0.54 0.2881 55RCS1_H2O2Hi YAF9 Krogan04 0.54 0.2882 46ACE2_YPD MOT1-42 Dasgupta02 0.54 0.2882 80SUM1_YPD gcn5_KQL Huisinga04 -0.54 0.2883 44YAP7_H2O2Hi IES6 Hughes00 -0.54 0.2883 139AFT2_H2O2Lo hat2_vs._hat1Rosaleny05 0.54 0.2883 86RLM1_YPD hpa2D Durant06 -0.54 0.2884 48

NRG1_YPD hpa2D Durant06 -0.54 0.2884 48OAF1_YPD HAT2 Hughes00 0.54 0.2884 54SWI5_YPD HTZ1 Krogan04 -0.53 0.2885 94YAP6_YPD hpa2D Durant06 -0.53 0.2886 68GCN4_YPD isw2 Fazzio01 0.53 0.2886 74HAP4_YPD spt10_del Xu05 -0.53 0.2886 67MCM1_YPD Dsap30 Keogh05 0.53 0.2886 76GLN3_RAPA WT_Null_K Chitikila_02 0.53 0.2893 62STE12_YPD ISW1 Hughes00 0.53 0.2894 54CIN5_YPD Dpho23 Keogh05 -0.53 0.2894 148ACE2_YPD PCH1 Hughes00 0.53 0.2896 78MBP1_H2O2HiUBP8 Hughes00 -0.53 0.2897 131ASH1_BUT14 sir4 Orlandi04 -0.53 0.2897 28UME6_YPD DT_V161E Chitikila_02 -0.53 0.2898 115FKH2_H2O2Hi MOT1-42 Dasgupta02 -0.53 0.2898 106TYE7_YPD DT_V71R Chitikila_02 -0.53 0.2901 54YAP6_YPD gcn5D Durant06 0.53 0.2902 75DAL82_RAPA ZDS1 Hughes00 0.53 0.2908 56TYE7_YPD htz1_del Mizuguch04 0.53 0.291 56NRG1_H2O2Hitaf1-ts2_spt3_E240KHuisinga04 -0.53 0.291 112DIG1_BUT14 _SWC2_(VPS72)Krogan04 0.53 0.291 62FKH1_YPD WT_WT Chitikila_02 -0.53 0.291 132TYE7_YPD hat1D Durant06 0.53 0.2911 44SUT1_YPD ARP4 Mnaimneh_04 0.53 0.2913 69OAF1_YPD hat2_vs._hat1Rosaleny05 -0.53 0.2914 53PHO4_YPD TUP1_haploid Hughes00 -0.53 0.2915 71REB1_H2O2Hi SIR3 Hughes00 0.53 0.2915 59REB1_H2O2Hi Dsin3 Keogh05 0.53 0.2915 52RTG3_RAPA arp8_+_0.1%_MMS_vs._arp8Attikum04 0.53 0.2916 43STE12_BUT90 YNG2 Mnaimneh_04 0.53 0.2916 78MBP1_H2O2Lorpd3_H4KQ_v_H4KQSabet04 0.53 0.2917 56HSF1_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 -0.53 0.2919 109STP1_SM hos3_del Bernstein_00_affydeletions-0.53 0.2921 65YAP6_H2O2Lo WT_N69S Chitikila_02 0.53 0.2921 53MCM1_YPD H4KQ Sabet04 0.53 0.2921 73RTG3_RAPA YNG2 Mnaimneh_04 0.53 0.2922 52MSN4_H2O2Hiisw2_rpd3_vs._rpd3Fazzio01 -0.53 0.2922 68SWI4_YPD SWD2 Mnaimneh_04 0.53 0.2923 156HSF1_H2O2Lo isw2_rpd3 Fazzio01 0.53 0.2923 97DIG1_BUT14 WT_Null_L Chitikila_02 0.53 0.2923 59RTG3_RAPA EAF7 Krogan04 0.53 0.2924 48RTG3_RAPA spt3 Huisinga04 0.53 0.2925 52SKN7_H2O2HiSIR1 Hughes00 0.53 0.2926 96TYE7_YPD SPT3 Ingvarsdottir05 0.53 0.2928 53UME6_H2O2HiHIR2 Hughes00 0.53 0.2931 100XBP1_H2O2Lo taf1-ts2_GCN5Huisinga04 -0.53 0.2935 66STE12_BUT90 sap30_del Bernstein_00_affydeletions0.53 0.2935 72DAL82_RAPA taf1-ts2_25C Huisinga04 0.53 0.2936 51YAP6_YPD esa1-414_taf1-ts2Durant06 0.53 0.2937 73MSN2_H2O2HiDT_N69R Chitikila_02 -0.53 0.2941 77RCS1_H2O2Hi SIR3 Hughes00 0.53 0.2941 52AFT2_H2O2Lo WT_N69R Chitikila_02 0.53 0.2942 91ABF1_YPD isw2_c.i._rpd3_c.i.Fazzio01 0.53 0.2945 261

RTG3_RAPA hat1_vs.YPH250Rosaleny05 -0.53 0.2945 51TYE7_YPD SPT8 Ingvarsdottir05 0.53 0.2949 52CIN5_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 0.53 0.2949 62STE12_Alpha DT_Null Chitikila_02 -0.53 0.295 108PHD1_YPD DT_V161R_L Chitikila_02 0.52 0.2952 61SUM1_YPD hht2_K4G Martin04 0.52 0.2952 25SKN7_YPD Dume1 Keogh05 -0.52 0.2953 58PUT3_H2O2Lo SAP30 Hughes00 0.52 0.2953 88YAP7_H2O2Hi EPL1 Mnaimneh_04 -0.52 0.2954 141RLM1_YPD TAF2 Mnaimneh_04 0.52 0.296 55DAL82_RAPA isw2_c.i. Fazzio01 -0.52 0.296 54NRG1_YPD taf1-ts2_spt3 Huisinga04 -0.52 0.2963 67PUT3_H2O2Lo Drxt1 Keogh05 -0.52 0.2964 88GCN4_YPD hht2_K4G Martin04 0.52 0.2964 66MCM1_YPD SIR4 Hughes00 0.52 0.2964 77RTG3_RAPA hos2_del Bernstein_00_affydeletions0.52 0.2965 48CIN5_YPD gcn5_KQL Huisinga04 -0.52 0.2966 123GCR2_SM DT_N69S Chitikila_02 -0.52 0.2966 51RIM101_H2O2LoPCH1 Hughes00 0.52 0.2966 52ROX1_YPD RSC8 Mnaimneh_04 -0.52 0.2969 67PHO4_YPD HAT2 Hughes00 -0.52 0.297 70YAP6_H2O2Hi WT_Null_K Chitikila_02 -0.52 0.297 75STP1_SM SSN6_haploid Hughes00 0.52 0.2974 66FKH1_YPD WT_N69S Chitikila_02 -0.52 0.2974 126DAL82_RAPA YNG2 Krogan04 0.52 0.2976 51PUT3_H2O2Lo TAF2 Mnaimneh_04 0.52 0.2976 87RPN4_H2O2LoWT_TAF1_SPT3Huisinga04 -0.52 0.2976 95XBP1_H2O2Lo sir4 Orlandi04 -0.52 0.2976 26STE12_YPD ubp10 Orlandi04 -0.52 0.2977 36SWI6_YPD IES6 Hughes00 -0.52 0.2977 153SUM1_YPD SWR1 Krogan04 -0.52 0.298 47DIG1_BUT14 ino80_del Mizuguch04 -0.52 0.298 63RCS1_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 -0.52 0.2983 50AFT2_H2O2Lo H4KQ Sabet04 0.52 0.2983 92DIG1_Alpha gcn5D_taf1-ts2Durant06 0.52 0.2983 49SKN7_H2O2HiHDA1 Hughes00 -0.52 0.2984 95FKH2_YPD TAF2 Mnaimneh_04 0.52 0.2985 121MSN4_H2O2HiHAT2 Hughes00 0.52 0.2986 68CIN5_H2O2Lo esa1-414 Durant06 0.52 0.2989 111ABF1_YPD hat2_vs._YPH250Rosaleny05 -0.52 0.2991 250DAL82_RAPA hht2K9131823GMartin04 -0.52 0.2991 39PHO4_YPD YNG2 Mnaimneh_04 -0.52 0.2993 72ASH1_BUT14 Drpd3 Keogh05 0.52 0.2995 46SOK2_BUT14 HAT2 Hughes00 0.52 0.2995 70YAP6_H2O2Lo SIR2 Hughes00 0.52 0.2997 58FKH1_YPD isw2_ume6 Fazzio01 -0.52 0.2998 139YAP6_H2O2Hi HST3 Hughes00 0.52 0.2999 78SOK2_BUT14 DT_N69R Chitikila_02 0.52 0.2999 67RTG3_RAPA DT_V71E Chitikila_02 0.52 0.3001 50CIN5_H2O2Hi Drxt1 Keogh05 -0.52 0.3002 79SUT1_YPD sas3D Durant06 -0.52 0.3003 56MCM1_YPD BUR6 Geisberg_01 0.52 0.3005 72CIN5_H2O2Hi swi1_minimal_medium_experimentSudarsanam00 0.52 0.3006 80

CIN5_H2O2Lo HAT2 Hughes00 -0.52 0.3008 125PHD1_YPD Dume1 Keogh05 -0.52 0.301 61HSF1_H2O2Hi sin3 Fazzio01 -0.52 0.301 119NDD1_YPD MOT1-42 Dasgupta02 -0.52 0.301 85REB1_YPD taf1-ts2 Durant06 -0.52 0.3012 139DIG1_Alpha H3KQ Sabet04 -0.52 0.3013 56DIG1_BUT14 DT_N69R Chitikila_02 0.52 0.3016 56STE12_YPD YNG2 Mnaimneh_04 0.52 0.3018 54FKH2_H2O2Hi swr1_del Mizuguch04 0.52 0.3018 105MBP1_H2O2Hiume6 Fazzio01 0.52 0.3018 126RCS1_H2O2Hi HST3 Hughes00 -0.52 0.3019 50CIN5_H2O2Lo taf1-ts2_SPT3 Huisinga04 0.52 0.3019 122GCN4_YPD Rpd3_del Bernstein02 0.51 0.302 75ASH1_BUT14 DT_N69R Chitikila_02 -0.51 0.3021 48FKH2_YPD IES6 Hughes00 0.51 0.3021 120FKH2_H2O2Hi ISW2 Hughes00 -0.51 0.3022 106HSF1_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 0.51 0.3022 102SWI5_YPD swi1_minimal_medium_experimentSudarsanam00 -0.51 0.3023 101NRG1_H2O2HiWT_WT Chitikila_02 -0.51 0.3023 116PHD1_BUT90 H3_1-28 Sabet04 0.51 0.3023 96NRG1_H2O2Hihht2K9131823GMartin04 0.51 0.3027 89MSN4_H2O2Hiisw2_ume6 Fazzio01 0.51 0.3028 68RCS1_H2O2Hi IES6 Hughes00 -0.51 0.303 52SKN7_YPD EAF5 Krogan04 0.51 0.3032 55STP1_SM RSC8 Mnaimneh_04 0.51 0.3034 68MBP1_H2O2Lohtz1 Meneghini03 0.51 0.3036 57MSN4_H2O2HiHDA1 Hughes00 0.51 0.3038 68RLM1_YPD isw2_ume6 Fazzio01 -0.51 0.3039 54OAF1_YPD Deaf3 Keogh05 0.51 0.3039 52AFT2_H2O2Lo hda1_del Bernstein_00_affydeletions0.51 0.304 88FKH1_YPD RSC8 Mnaimneh_04 -0.51 0.304 142UME6_YPD DT_WT Chitikila_02 -0.51 0.3041 118YAP1_YPD rsc3-2 Angus-Hill_01 0.51 0.3041 71CBF1_SM rpd3_del Sabet04 -0.51 0.3041 271PUT3_H2O2Lo SIR4 Hughes00 0.51 0.3042 88YAP6_H2O2Lo esa1-414 Durant06 -0.51 0.3042 51CIN5_H2O2Lo SWC6_(VPS71)Krogan04 -0.51 0.3043 110REB1_YPD IES6 Hughes00 0.51 0.3044 143FKH1_YPD Drpd3 Keogh05 0.51 0.3044 131FKH2_YPD sas3D_taf1-ts2Durant06 -0.51 0.3045 110PUT3_H2O2Lo ino80_del Mizuguch04 0.51 0.3046 88SOK2_BUT14 HST3 Hughes00 0.51 0.3046 72YAP6_H2O2Lo Dsap30 Keogh05 -0.51 0.3047 56MSN4_H2O2Hielp3D Durant06 0.51 0.3053 59SUT1_YPD WT_TAF1_SPT3Huisinga04 0.51 0.3055 65ABF1_YPD sin3 Fazzio01 -0.51 0.3056 263DAL82_SM ino80 Attikum04 0.51 0.3057 40DIG1_Alpha swi1_rich_medium_experimentSudarsanam00 0.51 0.3058 59ASH1_BUT14 set1 Boa03 0.51 0.3059 49YAP6_H2O2Lo hht2_K914182327GMartin04 -0.51 0.3062 34PHD1_YPD elp3D_taf1-ts2Durant06 -0.51 0.3063 43YAP7_H2O2Hi taf1-ts2_25C Huisinga04 -0.51 0.3063 130MBP1_YPD taf1-ts2_SPT3 Huisinga04 -0.51 0.3063 121

SKN7_YPD elp3D Durant06 -0.51 0.3064 57PHD1_BUT90 rsc3-2 Angus-Hill_01 0.51 0.3064 105MSN4_RAPA EAF5 Krogan04 0.51 0.3066 49MGA1_YPD hat2_vs._YPH250Rosaleny05 0.51 0.3066 59PHO4_YPD Dpho23 Keogh05 0.51 0.3067 72STE12_YPD MED2_haploid Hughes00 -0.51 0.3067 52YAP7_H2O2Lo rpd3_H4KQ_v_H4KQSabet04 -0.51 0.3067 147CIN5_YPD SGF11 Ingvarsdottir05 0.51 0.3069 127PHO4_YPD isw2_c.i._rpd3_c.i.Fazzio01 0.51 0.3072 70MBP1_YPD RAD6_haploid Hughes00 -0.51 0.3072 128NRG1_H2O2Hiubp10 Orlandi04 0.51 0.3074 71SOK2_BUT14 DT_V161R_K Chitikila_02 0.51 0.3075 69SKN7_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 -0.51 0.3076 95SKN7_H2O2HiDrco1 Keogh05 0.51 0.3076 91PUT3_H2O2Lo DT_WT Chitikila_02 -0.51 0.3077 83YAP1_YPD sas3D Durant06 0.51 0.3078 60OAF1_YPD ISW2 Hughes00 -0.51 0.3078 59RLM1_YPD SWR1 Krogan04 0.51 0.3082 54HSF1_H2O2LoDrxt2 Keogh05 0.51 0.3083 96STE12_BUT90 HIR2 Hughes00 -0.51 0.3083 76SKN7_H2O2Hi sir2 Meneghini03 -0.51 0.3084 98RCS1_H2O2Hi SIR4 Hughes00 0.51 0.3085 52PUT3_H2O2Lo htz1_sir2 Meneghini03 0.51 0.3087 86NDD1_YPD SAP30 Hughes00 0.51 0.3087 82TYE7_YPD taf1-ts2_spt3 Huisinga04 -0.51 0.3088 53DAL81_RAPA ino80 Attikum04 0.51 0.3089 73OAF1_YPD rsc30_null Angus-Hill_01 -0.5 0.3091 56MSN4_H2O2Hiarp8 Attikum04 -0.5 0.3092 59CBF1_SM hos2_del Bernstein_00_affydeletions0.5 0.3093 266NDD1_YPD hos2_del Bernstein_00_affydeletions0.5 0.3093 81REB1_YPD UBP8 Ingvarsdottir05 -0.5 0.3094 130DAL82_SM hht2_K27G Martin04 0.5 0.3095 40ROX1_YPD hat1D Durant06 -0.5 0.3096 40HSF1_H2O2Lo isw2_c.i._rpd3_c.i.Fazzio01 -0.5 0.3096 97PHO4_YPD rsc3-2 Angus-Hill_01 0.5 0.3097 70GCR2_SM isw2 Fazzio01 -0.5 0.3097 52DAL81_RAPA ino80_del Mizuguch04 -0.5 0.3097 95YAP1_YPD htz1 Meneghini03 0.5 0.3098 66HAP1_YPD sir4 Orlandi04 -0.5 0.3098 108RLM1_YPD DT_V161R_K Chitikila_02 -0.5 0.3099 52MSN4_RAPA isw2_c.i. Fazzio01 0.5 0.3099 53GCR2_SM rpd3_H3dN_v_H3dNSabet04 0.5 0.31 53AFT2_H2O2Lo taf1-ts2 Durant06 0.5 0.31 96MBP1_H2O2HiDT_V71R Chitikila_02 -0.5 0.3102 128GCN4_RAPA ino80_del Mizuguch04 0.5 0.3103 159CIN5_H2O2Lo htz1_sir2 Meneghini03 -0.5 0.3103 124RCS1_H2O2Hi taf1-ts2 Durant06 0.5 0.3104 52RIM101_H2O2LoDsin3 Keogh05 -0.5 0.3109 47AFT2_H2O2Hi sin3_del Bernstein_00_affydeletions0.5 0.311 54RCS1_H2O2LoDrpd3 Keogh05 0.5 0.311 231STE12_YPD hos2_del Bernstein_00_affydeletions0.5 0.3112 49SUM1_YPD SGF11 Ingvarsdottir05 -0.5 0.3112 47SKN7_H2O2HiMOT1-42 Dasgupta02 0.5 0.3113 98

GCN4_YPD elp3D Durant06 0.5 0.3113 63SWI5_YPD arp8 Attikum04 0.5 0.3115 79RIM101_H2O2Lohtz1_sir2 Meneghini03 -0.5 0.3115 53XBP1_H2O2Lo ZDS1 Hughes00 0.5 0.3116 67YAP6_YPD elp3D Durant06 0.5 0.3118 72NRG1_YPD gcn5D Durant06 -0.5 0.3121 59UME6_YPD WT_V161R_K Chitikila_02 -0.5 0.3124 114STP1_SM ino80 Attikum04 -0.5 0.3127 49PHO4_YPD HDA1 Hughes00 -0.5 0.3128 70HAP1_YPD IOC4 Hughes00 -0.5 0.3128 141DAL82_SM taf1-ts2_gcn5 Huisinga04 0.5 0.3129 55SKN7_H2O2HiDume1 Keogh05 0.5 0.3129 88OAF1_YPD SSN6_haploid Hughes00 0.5 0.3129 59SUT1_YPD hat2_vs._YPH250Rosaleny05 0.5 0.313 62PHO4_YPD sin3_del Bernstein_00_affydeletions-0.5 0.3131 69MBP1_YPD spt3_E240K Huisinga04 -0.5 0.3132 117SWI5_YPD Dume1 Keogh05 -0.5 0.3133 97AFT2_H2O2Lo ARD1 Hughes00 0.5 0.3133 98SKN7_H2O2LoPCH1 Hughes00 0.5 0.3133 184GCN4_RAPA hht2_K4G Martin04 0.5 0.3134 134REB1_H2O2Hi ISW1 Hughes00 -0.5 0.3135 59PHD1_YPD VID21 Krogan04 0.5 0.3136 59PUT3_H2O2Lo RAD6_haploid Hughes00 0.5 0.3136 87CBF1_SM DT_V71R Chitikila_02 0.5 0.3138 266GCN4_YPD rpd3_del Sabet04 -0.5 0.3138 75PHD1_YPD DT_N69R Chitikila_02 0.5 0.314 63STP1_SM taf1-ts2_GCN5Huisinga04 0.5 0.314 61MBP1_H2O2Hi sir2 Meneghini03 -0.5 0.3141 131CIN5_YPD htz1 Meneghini03 0.5 0.3142 148GCR2_SM Ddep1 Keogh05 0.5 0.3142 53AFT2_H2O2Hi taf1-ts2 Durant06 0.5 0.3143 60SKN7_YPD sin3_del Bernstein_00_affydeletions0.5 0.3144 54MSN4_RAPA htz1_hmr Meneghini03 0.5 0.3147 50ASH1_BUT14 gcn5 Huisinga04 -0.5 0.3148 49CIN5_YPD Ddep1 Keogh05 -0.5 0.3149 140YAP1_YPD hat2_vs._hat1Rosaleny05 0.5 0.315 70SUT1_YPD delta_ssd1 Kaeberlein04 0.5 0.3152 69RCS1_H2O2LoH4_2-26 Sabet04 -0.5 0.3153 253REB1_H2O2Hi gcn5D Durant06 0.5 0.3154 49ABF1_YPD ume6 Fazzio01 -0.5 0.3155 263SUT1_YPD WT_F182V Chitikila_02 0.5 0.3155 59ABF1_YPD hat2_vs._hat1Rosaleny05 0.5 0.3156 251STE12_BUT14 ISW2 Hughes00 -0.5 0.3157 128DAL82_SM HTZ1 Krogan04 0.5 0.3158 50MSN4_RAPA ino80_del Mizuguch04 -0.5 0.3158 54MBP1_YPD hos2_del Bernstein_00_affydeletions0.5 0.3159 125MCM1_YPD MOT1-14 Dasgupta02 0.5 0.3159 77MCM1_Alpha TUP1_haploid Hughes00 0.5 0.3161 106STE12_BUT14 TUP1_haploid Hughes00 -0.5 0.3162 127RCS1_H2O2Hi UBP8 Hughes00 0.49 0.3163 51YAP7_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 0.49 0.3163 138SUT1_YPD WT_Null_K Chitikila_02 -0.49 0.3164 68SKN7_H2O2Hi sap30_del Bernstein_00_affydeletions0.49 0.3164 86

NRG1_YPD WT_TAF1_GCN5Huisinga04 -0.49 0.3165 71YAP6_YPD ino80 Attikum04 0.49 0.3166 65UME6_H2O2Hihos2_del Bernstein_00_affydeletions-0.49 0.3167 96YAP1_YPD taf1-ts2_SPT3 Huisinga04 0.49 0.3169 69GLN3_RAPA ISW1 Hughes00 -0.49 0.317 68DAL82_RAPA SWD2 Mnaimneh_04 0.49 0.3171 56SWI6_YPD BUR6 Geisberg_01 -0.49 0.3172 144ROX1_YPD TAF2 Mnaimneh_04 0.49 0.3174 67RTG3_RAPA WT_WT Chitikila_02 -0.49 0.3174 50MCM1_Alpha isw2 Fazzio01 0.49 0.3175 104UME6_H2O2Hispt3_E240K Huisinga04 -0.49 0.3177 86REB1_H2O2Hi SWC6_(VPS71)Krogan04 -0.49 0.3178 54SWI5_YPD Deaf3 Keogh05 0.49 0.3179 90STE12_BUT90 TUP1_haploid Hughes00 -0.49 0.318 75SWI6_YPD WT Durant06 0.49 0.3183 147GCN4_SM VID21 Krogan04 -0.49 0.3183 175MBP1_H2O2Loswr1 Meneghini03 0.49 0.3185 48ABF1_YPD rpd3 Fazzio01 -0.49 0.3186 263SKN7_H2O2Loino80_+_0.1%_MMS_vs._ino80Attikum04 0.49 0.3186 142STE12_BUT14 WT_Null_L Chitikila_02 0.49 0.3186 120ACE2_YPD ume6 Fazzio01 -0.49 0.3186 74ROX1_YPD ubp10sir4 Orlandi04 -0.49 0.3187 36MGA1_YPD isw2_sin3_vs._sin3Fazzio01 0.49 0.3187 60SWI5_YPD Ddep1 Keogh05 0.49 0.3188 94HSF1_H2O2LoDT_V71R Chitikila_02 0.49 0.3189 100CIN5_H2O2Lo SIN3 Hughes00 -0.49 0.319 126MSN4_RAPA sin3_del Bernstein_00_affydeletions-0.49 0.3191 51TYE7_YPD HDA1 Hughes00 -0.49 0.3192 55YAP6_H2O2Lo arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.49 0.3193 42MCM1_Alpha spt3 Huisinga04 0.49 0.3193 104YAP6_YPD taf1-ts2_gcn5_KQLHuisinga04 0.49 0.3194 65SUM1_YPD gcn5D Durant06 -0.49 0.3195 37CIN5_H2O2Lo WT_V71R Chitikila_02 0.49 0.3199 113FKH1_YPD taf1-ts2_GCN5Huisinga04 -0.49 0.32 130SKN7_H2O2HiWT_Null_L Chitikila_02 0.49 0.3202 92PHO4_YPD hmr Meneghini03 0.49 0.3203 69TYE7_YPD WT_V161R_K Chitikila_02 -0.49 0.3203 51ACE2_YPD SPT3 Ingvarsdottir05 0.49 0.3203 72SWI5_YPD DT_WT Chitikila_02 -0.49 0.3204 91SWI4_YPD ume6_del Bernstein_00_affydeletions0.49 0.3205 147ACE2_YPD hht2_K914182327GMartin04 -0.49 0.3211 67RLM1_YPD SIN3 Hughes00 -0.49 0.3212 55FKH1_YPD RAD6_haploid Hughes00 -0.49 0.3212 139OAF1_YPD EPL1 Mnaimneh_04 0.49 0.3217 59GLN3_RAPA Dume1 Keogh05 -0.49 0.3218 63MBP1_H2O2HiMED2_haploid Hughes00 0.49 0.3219 132STE12_Alpha hat2_vs._YPH250Rosaleny05 -0.49 0.322 110DIG1_BUT14 ISW2 Hughes00 -0.49 0.3222 63CIN5_H2O2Hi WT_TAF1_SPT3Huisinga04 -0.49 0.3223 75YAP6_H2O2Lo hmr Meneghini03 -0.49 0.3224 57REB1_H2O2Hi isw2_c.i. Fazzio01 0.49 0.3225 56MCM1_YPD EPL1 Mnaimneh_04 0.49 0.3229 77CBF1_SM rsc30_null Angus-Hill_01 -0.49 0.3232 273

STP1_SM SIR2 Hughes00 0.49 0.3232 68AFT2_H2O2Lo SAP30 Hughes00 0.49 0.3232 98STE12_Alpha hos2_del Bernstein_00_affydeletions-0.49 0.3233 105SOK2_BUT14 WT_F182V Chitikila_02 0.49 0.3233 64PHD1_BUT90 _SWC2_(VPS72)Krogan04 0.49 0.3233 99DAL81_RAPA hht2_K914182327GMartin04 -0.49 0.3235 75DIG1_BUT14 WT_V161R_K Chitikila_02 0.48 0.3236 56STE12_BUT90 Dsds3 Keogh05 0.48 0.3236 76UME6_H2O2HiDM_vs._YPH250Rosaleny05 0.48 0.3237 93HAP4_YPD SGF11 Ingvarsdottir05 -0.48 0.3238 54SKN7_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 0.48 0.3239 88TYE7_YPD HIR2 Hughes00 0.48 0.324 55PHD1_YPD ARP4 Mnaimneh_04 0.48 0.3241 67MCM1_Alpha ubp10 Orlandi04 -0.48 0.3241 73SWI4_YPD ISW2 Hughes00 -0.48 0.3242 156PUT3_H2O2Lo isw2 Fazzio01 0.48 0.3243 86YAP1_YPD sin3 Fazzio01 0.48 0.3244 68MGA1_YPD snf2_minimal_medium_experimentSudarsanam00 -0.48 0.3244 62DIG1_Alpha DT_V161E Chitikila_02 -0.48 0.3245 52CBF1_SM taf1-ts2_gcn5 Huisinga04 0.48 0.3246 262YAP6_YPD hos3_del Bernstein_00_affydeletions-0.48 0.3247 78PHD1_BUT90 EAF5 Krogan04 -0.48 0.3247 92CIN5_H2O2Lo DT_V71R Chitikila_02 0.48 0.3248 120RPN4_H2O2Lohht2_K4914182327GMartin04 -0.48 0.3248 89SWI5_YPD sir2 Meneghini03 0.48 0.3249 100MBP1_H2O2Losnf2_rich_medium_experimentSudarsanam00 -0.48 0.3249 56STE12_Alpha WT_TAF1_GCN5Huisinga04 0.48 0.3249 111STE12_BUT90 rpd3 Fazzio01 -0.48 0.325 76SUT1_YPD RSC8 Mnaimneh_04 0.48 0.3251 69FKH2_H2O2Hi WT_Null_L Chitikila_02 -0.48 0.3253 99RIM101_H2O2LoDeaf3 Keogh05 -0.48 0.3253 47ACE2_YPD rsc3-2 Angus-Hill_01 0.48 0.3253 80SKN7_YPD Drxt2 Keogh05 -0.48 0.3254 64MSN4_H2O2Hisas3D Durant06 0.48 0.3254 57DIG1_Alpha SIR1 Hughes00 -0.48 0.3254 60GLN3_RAPA SSN6_haploid Hughes00 -0.48 0.3256 65RCS1_H2O2Loisw2_c.i. Fazzio01 0.48 0.3256 253DIG1_BUT14 RSC8 Mnaimneh_04 0.48 0.3256 63HSF1_H2O2Hi WT_WT Chitikila_02 -0.48 0.3257 121DIG1_BUT14 Drxt2 Keogh05 -0.48 0.326 62DAL82_RAPA taf1-ts2_spt3_E240KHuisinga04 0.48 0.3261 55REB1_H2O2Hi ino80_del Mizuguch04 0.48 0.3261 58OAF1_YPD rsc3-2 Angus-Hill_01 -0.48 0.3261 56HSF1_H2O2Hi snf2_rich_medium_experimentSudarsanam00 -0.48 0.3262 124MGA1_YPD esa1-414 Durant06 -0.48 0.3262 55GCN4_YPD hos3_del Bernstein_00_affydeletions-0.48 0.3264 75GCR2_SM hht2_K4G Martin04 -0.48 0.3266 45UME6_YPD taf1-ts2_spt3 Huisinga04 -0.48 0.3269 116DAL82_RAPA arp8_+_0.1%_MMS_vs._arp8Attikum04 0.48 0.3269 43MSN4_RAPA ume6_del Bernstein_00_affydeletions-0.48 0.3269 50DIG1_Alpha ino80_del Mizuguch04 -0.48 0.3269 60DAL82_SM MED2_haploid Hughes00 0.48 0.327 55MSN4_H2O2Higcn5_KQL Huisinga04 0.48 0.327 58

CIN5_H2O2Lo rpd3_H3dN_v_H3dNSabet04 -0.48 0.327 119NRG1_H2O2HiDsap30 Keogh05 -0.48 0.3272 120NRG1_YPD DT_V71E Chitikila_02 -0.48 0.3274 65AFT2_H2O2Hi hat1D_taf1-ts2Durant06 0.48 0.3275 51RCS1_H2O2LoHST3 Hughes00 -0.48 0.3277 254AFT2_H2O2Hi WT_N69R Chitikila_02 -0.48 0.3278 55OAF1_YPD EAF7 Krogan04 0.48 0.3283 53REB1_YPD rpd3_c.i. Fazzio01 0.48 0.3284 142SUT1_YPD hht2_K49141823GMartin04 0.48 0.3284 49SWI4_YPD Dpho23 Keogh05 0.48 0.3284 155MCM1_YPD elp3D Durant06 0.48 0.3285 58REB1_H2O2Hi DT_Null Chitikila_02 0.48 0.3286 57RCS1_H2O2Lo0.1%_MMS Attikum04 -0.48 0.3288 208NDD1_YPD SPT8 Ingvarsdottir05 -0.48 0.3288 77SWI6_YPD hht2_K4G Martin04 0.48 0.3291 131CIN5_H2O2Hi taf1-ts2 Durant06 -0.48 0.3292 80STE12_BUT90 Dsap30 Keogh05 0.48 0.3293 76SWI5_YPD hpa2D Durant06 -0.48 0.3295 83SKN7_H2O2Hi sin3_del Bernstein_00_affydeletions-0.48 0.3296 86GCN4_RAPA Dsds3 Keogh05 0.48 0.3297 139RCS1_H2O2Hi Ddep1 Keogh05 -0.48 0.3297 47FKH1_YPD arp8 Attikum04 0.48 0.3298 113YAP1_YPD elp3D Durant06 0.48 0.3301 64MBP1_H2O2HiRSC8 Mnaimneh_04 0.48 0.3302 132CIN5_H2O2Lo YNG2 Krogan04 0.48 0.3304 118ABF1_YPD isw2_rpd3_vs._rpd3Fazzio01 0.48 0.3307 263YAP1_YPD sas3D_taf1-ts2Durant06 0.48 0.3307 67REB1_H2O2Hi EPL1 Mnaimneh_04 -0.48 0.3307 59ABF1_YPD isw2_ume6 Fazzio01 -0.48 0.331 263GLN3_RAPA Drxt2 Keogh05 -0.48 0.331 64AFT2_H2O2Lo Dpho23 Keogh05 0.47 0.3313 95RCS1_H2O2LoDT_N69R Chitikila_02 0.47 0.3313 240DAL82_RAPA swr1_del Mizuguch04 -0.47 0.3315 56HAP1_YPD hat2_vs._hat1Rosaleny05 -0.47 0.3315 135REB1_YPD Rpd3_del Bernstein02 0.47 0.3316 140DAL82_SM DT_Null Chitikila_02 -0.47 0.3316 54SUM1_YPD hmr Meneghini03 0.47 0.3319 55AFT2_H2O2Hi DT_V161R_L Chitikila_02 -0.47 0.3319 55STE12_BUT90 DT_Null Chitikila_02 0.47 0.332 74MBP1_H2O2HiARP4 Mnaimneh_04 0.47 0.3321 133TYE7_YPD SIR1 Hughes00 0.47 0.3324 56SUM1_YPD taf1-ts2_SPT3 Huisinga04 -0.47 0.3325 52SUT1_YPD sir4 Orlandi04 -0.47 0.3325 40MSN4_RAPA isw2_rpd3_vs._rpd3Fazzio01 0.47 0.3325 53RLM1_YPD ISW2 Hughes00 -0.47 0.3328 54SWI6_YPD rpd3_del Sabet04 -0.47 0.3328 148RCS1_H2O2Lotaf1-ts2_25C Huisinga04 0.47 0.3329 234CIN5_H2O2Hi RAD6_haploid Hughes00 0.47 0.333 77ABF1_YPD SIR1 Hughes00 0.47 0.3331 265GLN3_RAPA gcn5_KQL Huisinga04 -0.47 0.3331 60STE12_Alpha spt10_del Xu05 -0.47 0.3331 112DIG1_BUT14 rpd3_c.i. Fazzio01 -0.47 0.3331 63ABF1_YPD SGF11 Ingvarsdottir05 -0.47 0.3332 225

MCM1_YPD YNG2 Krogan04 0.47 0.3332 73CIN5_YPD isw2_ume6 Fazzio01 0.47 0.3333 148XBP1_H2O2Lo EPL1 Mnaimneh_04 0.47 0.3333 68DIG1_BUT14 rsc30_null Angus-Hill_01 -0.47 0.3333 60FKH1_YPD taf1-ts2 Durant06 -0.47 0.3334 140STE12_Alpha set1 Boa03 -0.47 0.3336 112RTG3_RAPA DT_N69R Chitikila_02 0.47 0.3337 49RCS1_H2O2Loino80_del Mizuguch04 0.47 0.3339 257SKN7_H2O2Lohat2_vs._YPH250Rosaleny05 0.47 0.3339 178AFT2_H2O2Hi ARD1 Hughes00 0.47 0.3341 61RLM1_YPD taf1-ts2_gcn5_KQLHuisinga04 -0.47 0.3343 46MSN4_H2O2Hiisw2_c.i._rpd3_c.i.Fazzio01 0.47 0.3343 68REB1_H2O2Hi WT_F182V Chitikila_02 -0.47 0.3343 43HSF1_H2O2Lo isw2_sin3 Fazzio01 0.47 0.3343 97CIN5_H2O2Lo taf1-ts2_spt3_E240KHuisinga04 0.47 0.3344 113DAL81_RAPA gcn5D Durant06 0.47 0.3345 83OAF1_YPD MED2_haploid Hughes00 -0.47 0.3345 58GCN4_YPD taf1-ts2_spt3_E240KHuisinga04 0.47 0.3346 69SKN7_H2O2Hi hht2_K4914182327GMartin04 0.47 0.3347 77RTG3_RAPA gcn5 Huisinga04 0.47 0.3349 49PHO4_YPD sir2 Meneghini03 -0.47 0.335 71YAP1_YPD EAF5 Krogan04 0.47 0.3353 67CIN5_YPD EPL1 Mnaimneh_04 0.47 0.3353 150REB1_YPD isw2_rpd3 Fazzio01 0.47 0.3356 140GCN4_RAPA isw2_sin3 Fazzio01 0.47 0.3357 155DIG1_Alpha IES6 Hughes00 -0.47 0.3357 59STE12_YPD hat1D_taf1-ts2Durant06 0.47 0.3359 41ABF1_YPD HIR2 Hughes00 0.47 0.3361 259AFT2_H2O2Hi EPL1 Mnaimneh_04 0.47 0.3361 61TYE7_YPD snf2_minimal_medium_experimentSudarsanam00 -0.47 0.3363 55MBP1_H2O2HiDrco1 Keogh05 0.47 0.3364 125MCM1_Alpha taf1-ts2_SPT3 Huisinga04 0.47 0.3364 103YAP7_H2O2Lo UBP8 Ingvarsdottir05 0.47 0.3367 144DIG1_BUT14 SIR2 Hughes00 -0.47 0.3367 63UME6_YPD SWD2 Mnaimneh_04 0.47 0.3368 131MGA1_YPD DT_N69R Chitikila_02 0.47 0.3368 57SKN7_H2O2LoDsap30 Keogh05 -0.47 0.3369 181STE12_BUT90 HAT2 Hughes00 0.47 0.3371 77SUM1_YPD ume6 Fazzio01 0.47 0.3372 59PHO4_YPD DM_vs._YPH250Rosaleny05 -0.47 0.3375 65STE12_Alpha WT_Null_K Chitikila_02 0.47 0.3375 108STE12_BUT14 SSN6_haploid Hughes00 0.47 0.3375 126STE12_YPD H4KQ Sabet04 -0.47 0.3376 51PHO4_YPD WT_V161E Chitikila_02 0.47 0.3377 67STE12_BUT14 DM_vs._YPH250Rosaleny05 0.47 0.3379 114RLM1_YPD UBP8 Hughes00 0.47 0.338 55DAL81_RAPA swr1 Meneghini03 -0.47 0.338 74RIM101_H2O2LoH3_1-28 Sabet04 0.47 0.338 44TYE7_YPD WT_WT Chitikila_02 -0.47 0.3384 53HSF1_H2O2Hi 0.1%_MMS Attikum04 0.47 0.3385 104MBP1_YPD SIR1 Hughes00 -0.47 0.3385 128RCS1_H2O2Loswi1_minimal_medium_experimentSudarsanam00 -0.47 0.3388 257SKN7_YPD taf1-ts2_spt3_E240KHuisinga04 -0.46 0.339 61

TYE7_YPD esa1-414 Durant06 0.46 0.3391 51STP1_SM DT_V71E Chitikila_02 0.46 0.3391 64SWI5_YPD Hda1_del Bernstein02 -0.46 0.3392 99HSF1_H2O2LoARD1 Hughes00 0.46 0.3392 98RLM1_YPD SIR4 Hughes00 0.46 0.3393 55YAP6_YPD hht2_K4914182327GMartin04 -0.46 0.3394 62SKN7_H2O2Hi sas3D Durant06 0.46 0.3394 81FKH1_YPD H3_1-28 Sabet04 0.46 0.3394 138MGA1_YPD WT_Null_L Chitikila_02 0.46 0.3395 58CIN5_H2O2Lo Drxt2 Keogh05 -0.46 0.3397 118YAP6_H2O2Lo DT_WT Chitikila_02 0.46 0.3398 53SOK2_BUT14 hht2_K4G Martin04 0.46 0.3399 49DIG1_Alpha ubp10 Orlandi04 0.46 0.3401 34CIN5_H2O2Hi PCH1 Hughes00 -0.46 0.3402 77OAF1_YPD isw2 Fazzio01 0.46 0.3402 56CBF1_SM ARD1 Hughes00 0.46 0.3408 276DAL82_SM hht2_K4914182327GMartin04 0.46 0.3408 41ROX1_YPD gcn5_KQL Huisinga04 -0.46 0.3409 62MBP1_YPD ume6_del Bernstein_00_affydeletions-0.46 0.3411 124MCM1_Alpha WT_F182V Chitikila_02 0.46 0.3414 90SOK2_BUT14 ume6_del Bernstein_00_affydeletions0.46 0.3414 62SUM1_YPD TAF2 Mnaimneh_04 -0.46 0.3416 59GLN3_RAPA rsc3-2 Angus-Hill_01 -0.46 0.3417 66MBP1_YPD SIR3 Hughes00 -0.46 0.3418 130FKH2_H2O2Hi SGF11 Ingvarsdottir05 -0.46 0.342 85MGA1_YPD isw2 Fazzio01 -0.46 0.342 60PHO4_YPD IOC4 Hughes00 0.46 0.3422 71RCS1_H2O2Hi esa1-414 Durant06 -0.46 0.3422 48HSF1_H2O2Lo isw2_c.i. Fazzio01 0.46 0.3422 97MCM1_Alpha taf1-ts2_25C Huisinga04 0.46 0.3423 99STE12_BUT90 swr1_del Mizuguch04 0.46 0.3423 78MBP1_H2O2Hi sap30_del Bernstein_00_affydeletions0.46 0.3424 124MGA1_YPD Drxt1 Keogh05 -0.46 0.3424 63NDD1_YPD taf1-ts2_gcn5 Huisinga04 0.46 0.3424 82DAL81_RAPA hht2_K4G Martin04 -0.46 0.3425 74NRG1_H2O2HiDT_V161R_L Chitikila_02 -0.46 0.3425 114RPN4_H2O2LoIES6 Hughes00 0.46 0.3425 99STE12_Alpha WT_N69R Chitikila_02 0.46 0.3425 104GCN4_RAPA rsc30_null Angus-Hill_01 -0.46 0.3426 151MBP1_H2O2Loino80 Attikum04 -0.46 0.3426 46MBP1_YPD rsc3-2 Angus-Hill_01 -0.46 0.3428 129AFT2_H2O2Hi Dpho23 Keogh05 0.46 0.3429 60RPN4_H2O2LoDsds3 Keogh05 0.46 0.343 96ASH1_BUT14 PCH1 Hughes00 -0.46 0.343 50RCS1_H2O2Hi spt10_del Xu05 0.46 0.3431 52YAP6_YPD Deaf3 Keogh05 -0.46 0.3432 82SUM1_YPD HAT2 Hughes00 0.46 0.3434 59REB1_YPD Dpho23 Keogh05 -0.46 0.3435 142TYE7_YPD sas3D Durant06 0.46 0.3437 46GCN4_YPD SAP30 Hughes00 0.46 0.3438 75GCR2_SM hht2K9131823GMartin04 -0.46 0.344 46RCS1_H2O2LoDsap30 Keogh05 0.46 0.3443 239UME6_YPD hda1_del Bernstein_00_affydeletions0.46 0.3445 123

PHD1_BUT90 hht2_K27G Martin04 0.46 0.3447 78YAP6_H2O2Lo hos3_del Bernstein_00_affydeletions-0.46 0.3448 50FKH1_YPD hht2_K4914182327GMartin04 0.46 0.3448 123UME6_H2O2Hitaf1-ts2_spt3 Huisinga04 0.46 0.3449 93ACE2_YPD ISW2 Hughes00 -0.46 0.3452 79SKN7_H2O2Lohht2_K4914182327GMartin04 0.46 0.3454 150REB1_YPD rpd3_H4KQ_v_H4KQSabet04 0.46 0.3455 141YAP6_H2O2Lo PCH1 Hughes00 -0.46 0.3455 57DAL82_SM BUR6 Geisberg_01 0.46 0.3457 48CBF1_SM DT_N69R Chitikila_02 -0.46 0.3458 261STE12_YPD sas3D Durant06 -0.46 0.3459 36DAL82_SM WT_WT Chitikila_02 0.46 0.3459 53MBP1_H2O2Loubp10sir4 Orlandi04 0.46 0.3459 37GCN4_YPD hht2_K49141823GMartin04 0.46 0.3459 66CBF1_SM H3KQ Sabet04 0.46 0.3462 272GCN4_YPD WT Durant06 -0.46 0.3462 73UME6_YPD swr1 Meneghini03 0.46 0.3464 97YAP6_YPD Drpd3 Keogh05 -0.46 0.3465 82YAP7_H2O2Lo hpa2D Durant06 0.46 0.3467 116RCS1_H2O2LoSPT3 Ingvarsdottir05 0.45 0.3468 223RPN4_H2O2Loisw2 Fazzio01 0.45 0.3468 97DIG1_Alpha swr1_del Mizuguch04 0.45 0.3468 60SKN7_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 -0.45 0.3469 98AFT2_H2O2Lo WT_V71R Chitikila_02 0.45 0.3469 90MCM1_YPD taf1-ts2_SPT3 Huisinga04 -0.45 0.3471 75PHO4_YPD swi1_rich_medium_experimentSudarsanam00 -0.45 0.3472 71YAP1_YPD taf1-ts2_spt3 Huisinga04 -0.45 0.3474 67FKH2_H2O2Hi hht2_K27G Martin04 0.45 0.3475 89REB1_H2O2Hi sin3 Fazzio01 -0.45 0.3475 57RLM1_YPD hos3_del Bernstein_00_affydeletions0.45 0.3476 47AFT2_H2O2Hi sin3 Fazzio01 -0.45 0.3476 58ACE2_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.45 0.3479 66DAL82_SM sir4 Orlandi04 -0.45 0.3481 37SWI4_YPD TUP1_haploid Hughes00 -0.45 0.3483 156XBP1_H2O2Lo Dsap30 Keogh05 -0.45 0.3484 67SWI5_YPD VID21 Krogan04 0.45 0.3487 88DAL82_RAPA WT_V161R_L Chitikila_02 -0.45 0.3489 54SWI4_YPD ISW1_ISW2 Hughes00 0.45 0.3491 156FKH2_H2O2Hi ino80 Attikum04 -0.45 0.3491 81DIG1_BUT14 spt3 Huisinga04 -0.45 0.3492 60YAP1_YPD swi1_minimal_medium_experimentSudarsanam00 0.45 0.3493 71CIN5_YPD WT_Null_K Chitikila_02 0.45 0.3493 143UME6_H2O2Hihht2_K4G Martin04 0.45 0.3497 73YAP7_H2O2Hi arp8 Attikum04 -0.45 0.3497 118PHO4_YPD Drco1 Keogh05 0.45 0.35 71GCN4_RAPA spt10 Eriksson05 -0.45 0.35 157DAL82_RAPA ume6 Fazzio01 0.45 0.3502 53PUT3_H2O2Lo sas3D_taf1-ts2Durant06 0.45 0.3502 82ABF1_YPD EPL1 Mnaimneh_04 -0.45 0.3504 267SUT1_YPD SPT3 Ingvarsdottir05 -0.45 0.3505 60DAL82_RAPA taf1-ts2_GCN5Huisinga04 0.45 0.3506 53RTG3_RAPA taf1-ts2_25C Huisinga04 0.45 0.3506 47FKH2_YPD HAT2 Hughes00 0.45 0.3506 121

CIN5_H2O2Lo elp3D Durant06 -0.45 0.3508 100GCN4_SM EAF7 Krogan04 0.45 0.351 178REB1_YPD SAP30 Hughes00 -0.45 0.3511 140GCN4_RAPA isw2_ume6 Fazzio01 0.45 0.3512 155TYE7_YPD rsc3-2 Angus-Hill_01 -0.45 0.3513 53YAP6_H2O2Lo ISW1_ISW2 Hughes00 -0.45 0.3513 58STP1_SM TAF2 Mnaimneh_04 -0.45 0.3514 68YAP6_H2O2Lo snf2_rich_medium_experimentSudarsanam00 0.45 0.3514 58FKH2_YPD VID21 Krogan04 -0.45 0.3516 110HSF1_H2O2LoDrxt1 Keogh05 -0.45 0.3519 101RCS1_H2O2Hi RAD6_haploid Hughes00 -0.45 0.352 52SOK2_BUT14 EAF5 Krogan04 -0.45 0.3521 64MBP1_H2O2LoPCH1 Hughes00 -0.45 0.3522 58RIM101_H2O2Loino80_+_0.1%_MMS_vs._ino80Attikum04 -0.45 0.3522 32OAF1_YPD PCH1 Hughes00 -0.45 0.3522 58RCS1_H2O2Hi IOC4 Hughes00 -0.45 0.3523 51SKN7_H2O2HiSIR4 Hughes00 -0.45 0.3523 97DAL82_SM swr1_del Mizuguch04 0.45 0.3527 55RCS1_H2O2Hi YNG2 Krogan04 0.45 0.3528 49MCM1_Alpha SIR3 Hughes00 -0.45 0.3528 104UME6_H2O2HiISW1 Hughes00 0.45 0.3529 99OAF1_YPD ISW1_ISW2 Hughes00 0.45 0.3529 59CIN5_H2O2Hi WT_F182V Chitikila_02 0.45 0.353 65ROX1_YPD isw2_c.i. Fazzio01 -0.45 0.3531 67GLN3_RAPA sin3 Fazzio01 -0.45 0.3533 67RLM1_YPD Dpho23 Keogh05 -0.45 0.3535 54YAP7_H2O2Lo WT_N69S Chitikila_02 -0.45 0.3537 133TYE7_YPD ubp10sir4 Orlandi04 -0.45 0.3538 45YAP6_YPD Dsin3 Keogh05 -0.45 0.354 77SKN7_H2O2HiDpho23 Keogh05 -0.45 0.354 96YAP7_H2O2Lo ARD1 Hughes00 0.45 0.354 150RTG3_RAPA sin3_del Bernstein_00_affydeletions0.45 0.3541 49STE12_Alpha esa1-414_taf1-ts2Durant06 0.45 0.3543 105UME6_H2O2HiARD1 Hughes00 -0.45 0.3545 100YAP6_H2O2Lo Deaf3 Keogh05 -0.45 0.3546 49CIN5_H2O2Hi EAF5 Krogan04 -0.45 0.3548 70RLM1_YPD ubp10 Orlandi04 0.44 0.3549 37ROX1_YPD WT_V161R_L Chitikila_02 0.44 0.355 65YAP6_H2O2Hi hht2_K27G Martin04 -0.44 0.3552 51NRG1_YPD spt10_del Xu05 -0.44 0.3552 70SKN7_YPD hos3_del Bernstein_00_affydeletions0.44 0.3553 53CIN5_H2O2Lo swi1_rich_medium_experimentSudarsanam00 0.44 0.3553 127SWI4_YPD hht2_K4914182327GMartin04 0.44 0.3557 131GCR2_SM SIR2 Hughes00 0.44 0.3557 54YAP7_H2O2Hi delta_ssd1 Kaeberlein04 0.44 0.3557 141RCS1_H2O2LoDdep1 Keogh05 0.44 0.3557 231MCM1_Alpha DT_N69S Chitikila_02 0.44 0.3557 95STE12_BUT90 taf1-ts2_gcn5_KQLHuisinga04 -0.44 0.3557 63YAP1_YPD spt3 Huisinga04 -0.44 0.3559 69DIG1_Alpha EPL1 Mnaimneh_04 0.44 0.3559 60MSN4_RAPA elp3D Durant06 -0.44 0.3561 40GLN3_RAPA SWR1 Krogan04 0.44 0.3564 63MBP1_H2O2LoUBP8 Hughes00 -0.44 0.3565 57

FKH1_YPD EAF7 Krogan04 0.44 0.3566 131MSN2_H2O2Hiino80_del Mizuguch04 0.44 0.3569 77RPN4_H2O2Losnf2_rich_medium_experimentSudarsanam00 0.44 0.3575 100RLM1_YPD hat1D_taf1-ts2Durant06 0.44 0.3576 47YAP6_H2O2Hi rsc3-2 Angus-Hill_01 0.44 0.3578 78NDD1_YPD WT_Null_L Chitikila_02 -0.44 0.3578 81FKH1_YPD ume6 Fazzio01 0.44 0.3579 139FKH2_YPD YAF9 Krogan04 0.44 0.3579 116FKH2_H2O2Hi Hda1_del Bernstein02 -0.44 0.3581 105MCM1_Alpha Deaf3 Keogh05 0.44 0.3584 94FKH2_YPD hat2_vs._YPH250Rosaleny05 0.44 0.3585 115SKN7_H2O2Lohht2K9131823GMartin04 0.44 0.3589 151AFT2_H2O2Lo IOC4 Hughes00 -0.44 0.3591 96YAP7_H2O2Lo WT_Null_K Chitikila_02 -0.44 0.3591 148GCN4_SM RSC8 Mnaimneh_04 0.44 0.3592 189CBF1_SM isw2_c.i._rpd3_c.i.Fazzio01 0.44 0.3593 272MGA1_YPD EAF5 Krogan04 0.44 0.3593 59REB1_YPD EAF7 Krogan04 0.44 0.3595 131CIN5_YPD 0.1%_MMS Attikum04 -0.44 0.3596 119SWI5_YPD ISW1 Hughes00 0.44 0.3597 99SWI5_YPD ume6 Fazzio01 0.44 0.3599 94CIN5_YPD EAF5 Krogan04 0.44 0.3601 137SOK2_BUT14 YAF9 Krogan04 0.44 0.3602 69YAP6_YPD HTZ1 Krogan04 0.44 0.3605 85REB1_YPD set1 Boa03 -0.44 0.3606 137STP1_SM DT_N69R Chitikila_02 0.44 0.3607 64RCS1_H2O2Loisw2_ume6 Fazzio01 0.44 0.3607 253HAP4_YPD sir4 Orlandi04 -0.44 0.3608 47NDD1_YPD ino80 Attikum04 0.44 0.361 70STE12_Alpha sas3D_taf1-ts2Durant06 0.44 0.3612 100CIN5_H2O2Hi SIR1 Hughes00 -0.44 0.3613 79MSN4_RAPA arp8_+_0.1%_MMS_vs._arp8Attikum04 0.44 0.3616 40CIN5_H2O2Lo PCH1 Hughes00 -0.44 0.3616 124YAP6_H2O2Lo WT_Null_K Chitikila_02 -0.44 0.3619 56UME6_H2O2HiDume1 Keogh05 0.44 0.362 94MBP1_H2O2Losap30_del Bernstein_00_affydeletions-0.44 0.3621 53DIG1_Alpha WT_N69S Chitikila_02 0.44 0.363 52MCM1_Alpha hht2_K4G Martin04 0.44 0.363 89PHD1_BUT90 HTZ1 Krogan04 -0.43 0.3632 97STE12_BUT90 elp3D_taf1-ts2Durant06 0.43 0.3634 60TYE7_YPD H3KQ Sabet04 0.43 0.3635 55FKH2_YPD WT Durant06 0.43 0.3635 115RCS1_H2O2Lohat1D_taf1-ts2Durant06 0.43 0.3636 217REB1_YPD swi1_minimal_medium_experimentSudarsanam00 0.43 0.3639 143STP1_SM spt3_E240K Huisinga04 0.43 0.3639 63RTG3_RAPA Dsds3 Keogh05 -0.43 0.3639 46MBP1_H2O2Hi isw2_sin3_vs._sin3Fazzio01 -0.43 0.3639 126UME6_H2O2HiSSD1-V Kaeberlein04 0.43 0.3644 102MCM1_YPD isw2_rpd3_vs._rpd3Fazzio01 0.43 0.3644 73SUT1_YPD htz1_hmr Meneghini03 -0.43 0.3645 62STP1_SM gcn5_KQL Huisinga04 -0.43 0.3647 61FKH2_H2O2Hi rsc30_null Angus-Hill_01 0.43 0.3649 98SWI5_YPD snf2_rich_medium_experimentSudarsanam00 -0.43 0.365 100

MBP1_H2O2Hi taf1-ts2_SPT3 Huisinga04 -0.43 0.3654 123MBP1_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 0.43 0.3658 133UME6_H2O2HiBUR6 Geisberg_01 0.43 0.3658 94YAP7_H2O2Lo Dsds3 Keogh05 0.43 0.366 134MSN4_H2O2Hihht2_K914182327GMartin04 0.43 0.3661 61MSN4_RAPA WT_V71R Chitikila_02 0.43 0.3662 48STE12_Alpha ubp10sir4 Orlandi04 -0.43 0.3662 66DIG1_BUT14 Dsin3 Keogh05 -0.43 0.3663 55MCM1_YPD hat1_vs.YPH250Rosaleny05 -0.43 0.3664 72STE12_YPD snf2_rich_medium_experimentSudarsanam00 -0.43 0.3666 52SWI5_YPD snf2_minimal_medium_experimentSudarsanam00 -0.43 0.3666 101SKN7_H2O2HiSGF11 Ingvarsdottir05 0.43 0.3666 80ACE2_YPD Set1_del Bernstein02 -0.43 0.3666 80CIN5_YPD hpa2D Durant06 -0.43 0.3668 118SKN7_YPD sas3D Durant06 0.43 0.3671 56YAP6_H2O2Hi RSC8 Mnaimneh_04 0.43 0.3671 79SKN7_H2O2LoMOT1-42 Dasgupta02 0.43 0.3671 185MCM1_Alpha HDA1 Hughes00 -0.43 0.3672 106ACE2_YPD set1 Boa03 0.43 0.3672 80XBP1_H2O2Lo ubp10 Orlandi04 0.43 0.3673 30STE12_BUT90 SIR3 Hughes00 -0.43 0.3674 78DAL82_RAPA ISW1_ISW2 Hughes00 0.43 0.3675 56SWI5_YPD 0.1%_MMS Attikum04 -0.43 0.3678 80TYE7_YPD taf1-ts2_GCN5Huisinga04 0.43 0.368 51RLM1_YPD WT_V161E Chitikila_02 -0.43 0.3684 52MSN4_RAPA VID21 Krogan04 0.43 0.3684 44CIN5_H2O2Lo EAF5 Krogan04 -0.43 0.3685 115SWI5_YPD RAD6_haploid Hughes00 0.43 0.3687 98PUT3_H2O2Lo SPT8 Ingvarsdottir05 0.43 0.3687 77MSN4_H2O2Hihos2_del Bernstein_00_affydeletions0.43 0.3688 64ACE2_YPD spt3 Huisinga04 -0.43 0.3688 74MCM1_YPD DT_N69S Chitikila_02 0.43 0.3688 69OAF1_YPD isw2_c.i._rpd3_c.i.Fazzio01 0.43 0.3689 56RIM101_H2O2Lohat2_vs._YPH250Rosaleny05 -0.43 0.369 49STE12_BUT90 MOT1-14 Dasgupta02 0.43 0.369 77MCM1_YPD Drpd3 Keogh05 0.43 0.369 72MGA1_YPD YNG2 Krogan04 -0.43 0.369 61STE12_BUT90 hat2_vs._YPH250Rosaleny05 0.43 0.3691 74STE12_BUT90 DT_V71E Chitikila_02 -0.43 0.3693 74CBF1_SM sin3_del Bernstein_00_affydeletions0.43 0.3694 269YAP7_H2O2Hi ubp10 Orlandi04 -0.43 0.3695 94YAP7_H2O2Lo Dpho23 Keogh05 0.43 0.3695 149MGA1_YPD hmr Meneghini03 0.43 0.3696 59YAP1_YPD HTZ1 Krogan04 0.43 0.3697 67GCN4_RAPA DT_V71E Chitikila_02 0.43 0.3701 155NDD1_YPD HDA1 Hughes00 -0.43 0.3702 85MBP1_H2O2LoSPT3 Ingvarsdottir05 0.43 0.3703 50TYE7_YPD elp3D_taf1-ts2Durant06 0.43 0.3705 47HAP1_YPD Drco1 Keogh05 0.43 0.3705 134GCN4_SM ino80 Attikum04 -0.43 0.3708 159YAP6_H2O2Hi DT_WT Chitikila_02 0.43 0.3708 74SWI5_YPD rsc30_null Angus-Hill_01 -0.43 0.3709 98RCS1_H2O2Hi spt3 Huisinga04 -0.43 0.3709 51

FKH2_YPD rpd3_del Sabet04 0.43 0.371 119CIN5_YPD ubp10 Orlandi04 0.43 0.3711 92CIN5_H2O2Hi esa1-414_taf1-ts2Durant06 -0.43 0.3711 66FKH2_H2O2Hi hht2_K914182327GMartin04 0.43 0.3711 90ABF1_YPD htz1_hmr Meneghini03 -0.43 0.3713 259UME6_H2O2Hiino80_+_0.1%_MMS_vs._ino80Attikum04 0.43 0.3713 74YAP6_H2O2Hi hat1_vs.YPH250Rosaleny05 0.43 0.3713 68STE12_Alpha esa1-414 Durant06 0.43 0.3713 107MCM1_YPD ISW1 Hughes00 0.43 0.3714 77AFT2_H2O2Hi SWR1 Krogan04 -0.42 0.3718 54MGA1_YPD TUP1_haploid Hughes00 -0.42 0.3721 61STP1_SM WT_Null_L Chitikila_02 0.42 0.3722 61REB1_H2O2Hi EAF7 Krogan04 -0.42 0.3722 54RCS1_H2O2Loarp8 Attikum04 -0.42 0.3724 197ROX1_YPD UBP8 Hughes00 0.42 0.3725 66AFT2_H2O2Lo SIR1 Hughes00 0.42 0.3725 97PHO4_YPD SSD1-V Kaeberlein04 0.42 0.3727 71RPN4_H2O2Loarp8 Attikum04 -0.42 0.3727 82MSN4_H2O2Hiume6_del Bernstein_00_affydeletions0.42 0.3731 64FKH2_YPD spt10 Eriksson05 -0.42 0.3731 119MCM1_YPD taf1-ts2_gcn5 Huisinga04 0.42 0.3731 74PUT3_H2O2Lo Dume1 Keogh05 -0.42 0.3738 77RCS1_H2O2LoZDS1 Hughes00 -0.42 0.3738 256XBP1_H2O2Lo EAF5 Krogan04 0.42 0.374 64REB1_YPD SIR1 Hughes00 0.42 0.3743 144STP1_SM ISW2 Hughes00 0.42 0.3743 68YAP6_H2O2Hi ISW1 Hughes00 -0.42 0.3747 78YAP6_H2O2Hi hht2_K914182327GMartin04 0.42 0.3747 51YAP7_H2O2Hi sin3_del Bernstein_00_affydeletions-0.42 0.3749 137HAP1_YPD SGF11 Ingvarsdottir05 0.42 0.375 123GCR2_SM hpa2D Durant06 0.42 0.3753 46AFT2_H2O2Lo esa1-414 Durant06 0.42 0.3753 92RCS1_H2O2Loswr1_del Mizuguch04 -0.42 0.3753 258GCN4_RAPA SSD1-V Kaeberlein04 0.42 0.3754 160MGA1_YPD esa1-414_taf1-ts2Durant06 -0.42 0.3754 55PUT3_H2O2Lo Drxt2 Keogh05 -0.42 0.3756 83SUM1_YPD HDA1 Hughes00 -0.42 0.3757 58SKN7_H2O2HiWT_WT Chitikila_02 -0.42 0.3759 96RTG3_RAPA rpd3_H4KQ_v_H4KQSabet04 -0.42 0.376 50AFT2_H2O2Hi DT_V161R_K Chitikila_02 -0.42 0.376 56RCS1_H2O2Lorpd3_H3dN_v_H3dNSabet04 0.42 0.376 253YAP6_H2O2Lo esa1-414_taf1-ts2Durant06 -0.42 0.3762 47MCM1_Alpha swr1_del Mizuguch04 0.42 0.3771 106GCN4_YPD spt10_del Xu05 -0.42 0.3771 74DAL81_RAPA EAF5 Krogan04 0.42 0.3773 87MSN4_RAPA YNG2 Mnaimneh_04 -0.42 0.3775 54PHD1_BUT90 hpa2D_taf1-ts2Durant06 0.42 0.3777 75SKN7_YPD sin3 Fazzio01 0.42 0.378 63RCS1_H2O2Hi SIN3 Hughes00 0.42 0.378 52AFT2_H2O2Hi sas3D_taf1-ts2Durant06 0.42 0.3781 56MBP1_H2O2LoBUR6 Geisberg_01 -0.42 0.3784 52RIM101_H2O2LoDT_N69S Chitikila_02 -0.42 0.3784 48PHD1_BUT90 HAT2 Hughes00 0.42 0.3784 105

SWI4_YPD hpa2D_taf1-ts2Durant06 0.42 0.3785 118SKN7_H2O2Hi swr1 Meneghini03 0.42 0.3785 76YAP7_H2O2Lo MED2_haploid Hughes00 -0.42 0.3785 151YAP6_H2O2Hi HAT2 Hughes00 -0.42 0.3796 76DAL82_SM elp3D Durant06 -0.41 0.3802 45MSN4_H2O2HiWT_N69S Chitikila_02 -0.41 0.3802 63MBP1_H2O2LoWT_V71R Chitikila_02 -0.41 0.3802 53ROX1_YPD ARD1 Hughes00 -0.41 0.3803 65RTG3_RAPA RPD3_haploid Hughes00 -0.41 0.3803 52DIG1_Alpha SSD1-V Kaeberlein04 0.41 0.3804 59REB1_H2O2Hi 0.1%_MMS Attikum04 0.41 0.3806 49YAP6_H2O2Lo DT_V161R_L Chitikila_02 0.41 0.3806 53PUT3_H2O2Lo WT_N69S Chitikila_02 0.41 0.3807 76YAP7_H2O2Lo Hda1_del Bernstein02 0.41 0.3807 151DAL81_RAPA hat2_vs._hat1Rosaleny05 -0.41 0.3809 91YAP1_YPD DT_V71R Chitikila_02 0.41 0.3811 70DAL82_SM Rpd3_del Bernstein02 -0.41 0.3811 54GCN4_SM SSN6_haploid Hughes00 -0.41 0.3811 188ABF1_YPD DT_V161R_K Chitikila_02 0.41 0.3818 258REB1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -0.41 0.3819 142ROX1_YPD htz1_sir2 Meneghini03 -0.41 0.382 66MCM1_YPD WT_V161R_L Chitikila_02 0.41 0.3821 71FKH1_YPD spt10_del Xu05 -0.41 0.3822 139MBP1_YPD Dume1 Keogh05 -0.41 0.3823 121DAL81_RAPA hht2_K27G Martin04 -0.41 0.3824 75STE12_BUT14 Deaf3 Keogh05 -0.41 0.3824 116RIM101_H2O2Lohht2_K914182327GMartin04 0.41 0.3828 31YAP6_H2O2Hi gcn5D Durant06 -0.41 0.3829 63STE12_BUT90 hmr Meneghini03 -0.41 0.383 77MBP1_H2O2LoTAF2 Mnaimneh_04 -0.41 0.3831 58DAL81_RAPA YNG2 Krogan04 0.41 0.3833 86ABF1_YPD HTZ1 Krogan04 -0.41 0.3835 247MSN4_RAPA DM_vs._YPH250Rosaleny05 -0.41 0.3836 52HSF1_H2O2Hi MOT1-14 Dasgupta02 0.41 0.3836 120DAL82_SM SSN6_haploid Hughes00 0.41 0.3839 54MCM1_Alpha HIR2 Hughes00 0.41 0.3839 106HAP4_YPD gcn5_KQL Huisinga04 -0.41 0.384 61YAP6_YPD WT_Null_K Chitikila_02 -0.41 0.3843 88GCN4_YPD RPD3_haploid Hughes00 0.41 0.3843 75MSN4_RAPA gcn5 Huisinga04 -0.41 0.3845 51SKN7_H2O2LoHAT2 Hughes00 0.41 0.3845 179STP1_SM ubp10sir4 Orlandi04 0.41 0.3846 43TYE7_YPD ARD1 Hughes00 -0.41 0.3848 56TYE7_YPD gcn5D_taf1-ts2Durant06 0.41 0.3848 52STE12_Alpha rsc30_null Angus-Hill_01 -0.41 0.3852 112SWI4_YPD taf1-ts2_25C Huisinga04 0.41 0.3853 140XBP1_H2O2Lo WT_V71E Chitikila_02 0.41 0.3853 52PHO4_YPD elp3D_taf1-ts2Durant06 -0.41 0.3854 61DIG1_Alpha ARD1 Hughes00 -0.41 0.3855 59FKH1_YPD Deaf3 Keogh05 0.41 0.3855 132SKN7_H2O2Hi arp8 Attikum04 0.41 0.3856 73ABF1_YPD DT_Null Chitikila_02 0.41 0.3857 251DAL81_RAPA WT_Null_L Chitikila_02 0.41 0.386 87

SWI6_YPD SWD2 Mnaimneh_04 0.41 0.3861 153MBP1_YPD gcn5D_taf1-ts2Durant06 -0.41 0.3862 120SWI4_YPD rsc30_null Angus-Hill_01 0.41 0.3863 153YAP1_YPD swr1 Meneghini03 -0.41 0.3863 58OAF1_YPD WT_Null_L Chitikila_02 -0.41 0.3863 52YAP7_H2O2Lo WT_TAF1_GCN5Huisinga04 0.41 0.3864 150GCN4_SM isw2_sin3 Fazzio01 0.41 0.3866 183STP1_SM spt3 Huisinga04 0.41 0.3868 66CIN5_H2O2Lo Dsin3 Keogh05 -0.41 0.3869 108CIN5_YPD Dume1 Keogh05 0.41 0.387 138PHO4_YPD UBP8 Hughes00 -0.41 0.3872 69MCM1_Alpha spt10_del Xu05 -0.41 0.3873 105NDD1_YPD Drxt1 Keogh05 -0.41 0.3873 84HSF1_H2O2Lohht2_K27G Martin04 0.41 0.3874 84RIM101_H2O2LoWT_V161R_L Chitikila_02 0.41 0.3874 50FKH2_YPD snf2_rich_medium_experimentSudarsanam00 0.41 0.3875 121OAF1_YPD ISW1 Hughes00 0.41 0.3876 59RLM1_YPD SPT3 Ingvarsdottir05 0.41 0.3877 48YAP1_YPD taf1-ts2_GCN5Huisinga04 0.41 0.3877 66PHD1_BUT90 htz1_sir2 Meneghini03 0.41 0.3877 105HAP4_YPD hat1D_taf1-ts2Durant06 -0.41 0.3877 55UME6_H2O2Hiisw2 Fazzio01 0.41 0.3878 97MGA1_YPD htz1_sir2 Meneghini03 -0.41 0.3879 58AFT2_H2O2Hi hht2_K914182327GMartin04 0.41 0.388 43NRG1_H2O2Hirpd3_c.i. Fazzio01 -0.41 0.388 123RCS1_H2O2LoDeaf3 Keogh05 0.41 0.388 233MCM1_YPD ino80 Attikum04 -0.41 0.3881 57RLM1_YPD spt10_del Xu05 -0.41 0.3882 53FKH1_YPD HTZ1 Krogan04 0.41 0.3883 128RLM1_YPD htz1_del Mizuguch04 0.41 0.3884 55ROX1_YPD swr1 Meneghini03 -0.41 0.3886 55GCN4_YPD YNG2 Krogan04 -0.41 0.3886 69MBP1_H2O2HiWT_Null_L Chitikila_02 -0.41 0.3888 126AFT2_H2O2Lo DT_Null Chitikila_02 -0.41 0.389 96GCN4_RAPA TAF2 Mnaimneh_04 -0.4 0.3893 160MBP1_H2O2Higcn5D_taf1-ts2Durant06 0.4 0.3893 123PHD1_YPD DT_V71E Chitikila_02 -0.4 0.3894 65OAF1_YPD gcn5D Durant06 -0.4 0.3895 49MBP1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.4 0.3897 111REB1_YPD BUR6 Geisberg_01 -0.4 0.3898 140SUM1_YPD WT_V161E Chitikila_02 -0.4 0.3899 51RCS1_H2O2Hi SWC6_(VPS71)Krogan04 -0.4 0.3899 45CIN5_H2O2Lo SAP30 Hughes00 -0.4 0.3899 126SWI4_YPD hht2K9131823GMartin04 0.4 0.3902 131REB1_YPD rpd3 Fazzio01 -0.4 0.3904 142SUM1_YPD UBP8 Ingvarsdottir05 -0.4 0.3904 52STE12_BUT14 arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.4 0.3905 107MGA1_YPD ino80 Attikum04 0.4 0.3906 46YAP6_YPD DT_N69R Chitikila_02 0.4 0.3909 86STE12_Alpha DT_V71R Chitikila_02 -0.4 0.3915 107MCM1_YPD isw2_sin3_vs._sin3Fazzio01 0.4 0.3915 73FKH1_YPD SGF11 Ingvarsdottir05 0.4 0.3917 122RCS1_H2O2Hi elp3D_taf1-ts2Durant06 0.4 0.3918 40

RLM1_YPD rsc30_null Angus-Hill_01 0.4 0.3921 53RCS1_H2O2Hi WT_V161R_L Chitikila_02 -0.4 0.3923 46CIN5_H2O2Hi elp3D_taf1-ts2Durant06 -0.4 0.3924 56YAP1_YPD ume6_del Bernstein_00_affydeletions0.4 0.3925 68GCN4_RAPA YNG2 Krogan04 0.4 0.3925 155HAP1_YPD YAF9 Krogan04 0.4 0.3925 134FKH1_YPD snf2_rich_medium_experimentSudarsanam00 -0.4 0.3926 142REB1_YPD WT_WT Chitikila_02 0.4 0.3929 136DAL82_RAPA Dume1 Keogh05 -0.4 0.3931 50HSF1_H2O2Hi Dpho23 Keogh05 0.4 0.3931 123YAP7_H2O2Hi hat1D Durant06 0.4 0.3934 112SOK2_BUT14 rpd3_H3dN_v_H3dNSabet04 -0.4 0.3934 65NRG1_YPD EAF5 Krogan04 -0.4 0.3935 62UME6_YPD WT_V161R_L Chitikila_02 -0.4 0.3936 119GLN3_RAPA arp8 Attikum04 0.4 0.3936 54REB1_H2O2Hi Rpd3_del Bernstein02 0.4 0.3937 58CIN5_H2O2Lo hht2_K4914182327GMartin04 -0.4 0.3937 87SWI6_YPD H4KQ Sabet04 0.4 0.3938 148DIG1_Alpha WT_TAF1_GCN5Huisinga04 0.4 0.394 58STE12_BUT90 hat1D Durant06 0.4 0.3941 61NDD1_YPD HST3 Hughes00 -0.4 0.3941 84MSN4_RAPA SAP30 Hughes00 -0.4 0.3944 54YAP6_H2O2Hi rpd3_del Sabet04 -0.4 0.3944 71ROX1_YPD SPT3 Ingvarsdottir05 -0.4 0.3946 61AFT2_H2O2Lo rpd3 Fazzio01 0.4 0.3946 95RIM101_H2O2Loesa1-414 Durant06 -0.4 0.3948 47RCS1_H2O2Logcn5_KQL Huisinga04 -0.4 0.395 227ABF1_YPD rpd3_H4KQ_v_H4KQSabet04 0.4 0.3951 260HSF1_H2O2Hi rpd3 Fazzio01 0.4 0.3954 119RCS1_H2O2Loisw2_sin3_vs._sin3Fazzio01 -0.4 0.3954 252CBF1_SM EAF5 Krogan04 0.4 0.3956 247ABF1_YPD PCH1 Hughes00 -0.4 0.3957 258UME6_YPD swr1_del Mizuguch04 0.4 0.3957 131CBF1_SM DT_WT Chitikila_02 -0.4 0.3958 266AFT2_H2O2Hi DT_V161E Chitikila_02 -0.4 0.396 55UME6_H2O2Hitaf1-ts2_spt3_E240KHuisinga04 0.4 0.396 93REB1_YPD gcn5D Durant06 0.4 0.3962 126SOK2_BUT14 htz1_hmr Meneghini03 0.4 0.3962 69RLM1_YPD H3KQ Sabet04 -0.4 0.3963 50FKH2_YPD rsc3-2 Angus-Hill_01 -0.4 0.3963 114HAP4_YPD sin3_del Bernstein_00_affydeletions0.4 0.3963 59STE12_BUT14 Drxt2 Keogh05 -0.4 0.3964 123HSF1_H2O2Hi YAF9 Krogan04 0.4 0.3967 120OAF1_YPD SIR2 Hughes00 -0.4 0.3969 57MBP1_H2O2LoYNG2 Mnaimneh_04 0.4 0.3972 58FKH1_YPD ume6_del Bernstein_00_affydeletions-0.4 0.3972 136RPN4_H2O2Logcn5D Durant06 -0.4 0.3973 90YAP7_H2O2Lo WT_V71R Chitikila_02 -0.4 0.3974 141GLN3_RAPA set1 Boa03 0.4 0.3975 65AFT2_H2O2Lo hpa2D_taf1-ts2Durant06 0.4 0.3975 73MGA1_YPD taf1-ts2_25C Huisinga04 0.4 0.3977 57DIG1_BUT14 ubp10sir4 Orlandi04 -0.4 0.3978 42HAP1_YPD swi1_rich_medium_experimentSudarsanam00 0.4 0.3979 141

REB1_YPD DT_V161R_K Chitikila_02 -0.4 0.3981 136REB1_H2O2Hi sap30_del Bernstein_00_affydeletions0.39 0.3982 56SWI5_YPD DT_V161R_K Chitikila_02 -0.39 0.3983 93SUT1_YPD Dume1 Keogh05 -0.39 0.3985 63PHD1_YPD hht2_K4G Martin04 -0.39 0.3987 48YAP6_H2O2Lo Drco1 Keogh05 0.39 0.3988 56RLM1_YPD WT_V161R_L Chitikila_02 -0.39 0.3989 52PHD1_BUT90 spt10 Eriksson05 0.39 0.3989 98ABF1_YPD SSD1-V Kaeberlein04 0.39 0.399 266SWI5_YPD hda1_del Bernstein_00_affydeletions0.39 0.399 87MSN4_H2O2HiIOC4 Hughes00 -0.39 0.399 67CBF1_SM isw2 Fazzio01 0.39 0.3993 272MCM1_Alpha WT_TAF1_GCN5Huisinga04 0.39 0.3993 106STE12_Alpha HST3 Hughes00 -0.39 0.3993 114OAF1_YPD DT_V71R Chitikila_02 -0.39 0.3995 57STE12_YPD hat2_vs._YPH250Rosaleny05 0.39 0.4 51MBP1_H2O2LoISW2 Hughes00 -0.39 0.4 58ROX1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -0.39 0.4003 67DAL82_RAPA swi1_minimal_medium_experimentSudarsanam00 -0.39 0.4004 56YAP7_H2O2Lo arp8 Attikum04 -0.39 0.4005 121NDD1_YPD IOC4 Hughes00 -0.39 0.4006 85SWI6_YPD isw2_ume6 Fazzio01 -0.39 0.4008 148REB1_YPD htz1 Meneghini03 0.39 0.4009 137RTG3_RAPA hat2_vs._YPH250Rosaleny05 -0.39 0.4009 51TYE7_YPD ume6_del Bernstein_00_affydeletions0.39 0.401 55SKN7_H2O2HiHIR2 Hughes00 -0.39 0.401 95GCR2_SM hht2_K27G Martin04 0.39 0.4013 46OAF1_YPD isw2_c.i. Fazzio01 -0.39 0.4014 56MCM1_Alpha DT_WT Chitikila_02 0.39 0.4017 102YAP7_H2O2Hi WT_V71E Chitikila_02 -0.39 0.4018 129RCS1_H2O2Loisw2_rpd3_vs._rpd3Fazzio01 0.39 0.4018 253DAL82_RAPA SSD1-V Kaeberlein04 0.39 0.402 56CIN5_H2O2Lo hos3_del Bernstein_00_affydeletions-0.39 0.4021 108MCM1_Alpha ino80_del Mizuguch04 0.39 0.4021 106HSF1_H2O2LoWT Durant06 -0.39 0.4024 94YAP7_H2O2Hi SIN3 Hughes00 0.39 0.4025 141NRG1_H2O2Hispt10 Eriksson05 0.39 0.4026 123MBP1_YPD TUP1_haploid Hughes00 -0.39 0.4026 130MGA1_YPD Drxt2 Keogh05 -0.39 0.4026 60HSF1_H2O2Hi SIR4 Hughes00 -0.39 0.4028 123MGA1_YPD 0.1%_MMS Attikum04 0.39 0.4028 48NDD1_YPD gcn5D Durant06 0.39 0.4028 80MSN2_H2O2Hihht2_K4914182327GMartin04 -0.39 0.4029 67DIG1_Alpha WT_V71E Chitikila_02 -0.39 0.4029 41XBP1_H2O2Lo SAP30 Hughes00 -0.39 0.403 67REB1_YPD WT_V161R_K Chitikila_02 0.39 0.4031 125ROX1_YPD taf1-ts2_25C Huisinga04 -0.39 0.4031 62STE12_YPD ISW2 Hughes00 -0.39 0.4031 54TYE7_YPD WT Durant06 0.39 0.4034 51DAL82_SM TUP1_haploid Hughes00 0.39 0.4036 55TYE7_YPD hos2_del Bernstein_00_affydeletions0.39 0.4037 54YAP7_H2O2Hi hat2_vs._YPH250Rosaleny05 0.39 0.4038 140CIN5_H2O2Lo Drpd3 Keogh05 -0.39 0.4038 115

RCS1_H2O2LoH3_1-28 Sabet04 0.39 0.404 253DAL82_RAPA swr1 Meneghini03 -0.39 0.4041 42PHD1_BUT90 Dume1 Keogh05 -0.39 0.4041 98YAP7_H2O2Hi spt10 Eriksson05 0.39 0.4043 140GCR2_SM BUR6 Geisberg_01 -0.39 0.4044 49ABF1_YPD SWD2 Mnaimneh_04 0.39 0.4048 267AFT2_H2O2Hi hos3_del Bernstein_00_affydeletions-0.39 0.4048 53MSN2_H2O2Hiisw2_c.i._rpd3_c.i.Fazzio01 0.39 0.4048 75STE12_BUT90 isw2_ume6 Fazzio01 -0.39 0.4048 77NRG1_YPD EAF7 Krogan04 -0.39 0.4048 65PHO4_YPD Dsap30 Keogh05 -0.39 0.405 67FKH2_H2O2Hi EAF5 Krogan04 -0.39 0.405 96SWI6_YPD H3_1-28 Sabet04 -0.39 0.4051 148FKH2_H2O2Hi YAF9 Krogan04 0.39 0.4051 103YAP6_H2O2Lo EPL1 Mnaimneh_04 -0.39 0.4052 59YAP7_H2O2Hi HAT2 Hughes00 -0.39 0.4053 140MBP1_H2O2LoRSC8 Mnaimneh_04 -0.39 0.4053 58STE12_Alpha RSC8 Mnaimneh_04 0.39 0.4058 115AFT2_H2O2Hi DT_WT Chitikila_02 -0.39 0.406 60GCN4_YPD ARP4 Mnaimneh_04 0.39 0.4061 75REB1_YPD hos3_del Bernstein_00_affydeletions0.39 0.4062 138PUT3_H2O2Lo elp3D Durant06 0.39 0.4062 74DAL81_RAPA ino80_+_0.1%_MMS_vs._ino80Attikum04 0.39 0.4064 77HSF1_H2O2LoSIR4 Hughes00 -0.39 0.4067 100OAF1_YPD hht2_K49141823GMartin04 0.39 0.4067 42SKN7_H2O2HiWT_TAF1_SPT3Huisinga04 0.39 0.4068 93RCS1_H2O2Hi hht2_K4914182327GMartin04 -0.39 0.4069 39YAP6_H2O2Hi isw2_ume6 Fazzio01 0.39 0.4069 73RCS1_H2O2Hi Hda1_del Bernstein02 0.39 0.4071 52RCS1_H2O2Lohtz1_sir2 Meneghini03 -0.39 0.4071 249HAP4_YPD ARD1 Hughes00 0.39 0.4071 65CIN5_H2O2Lo ume6_del Bernstein_00_affydeletions0.39 0.4073 110TYE7_YPD Drxt2 Keogh05 -0.38 0.4076 53AFT2_H2O2Lo sin3_del Bernstein_00_affydeletions-0.38 0.4079 85UME6_YPD rsc30_null Angus-Hill_01 -0.38 0.408 129YAP6_YPD WT_N69S Chitikila_02 0.38 0.408 84STP1_SM H4KQ Sabet04 -0.38 0.408 67REB1_H2O2Hi swr1_del Mizuguch04 -0.38 0.4084 59YAP6_H2O2Hi set1 Boa03 -0.38 0.4085 79DIG1_BUT14 WT_N69R Chitikila_02 0.38 0.4086 56RLM1_YPD gcn5D_taf1-ts2Durant06 0.38 0.4088 51MSN4_RAPA hpa2D Durant06 0.38 0.4089 35NRG1_YPD ubp10sir4 Orlandi04 -0.38 0.409 23MCM1_YPD hat1D_taf1-ts2Durant06 0.38 0.4091 57FKH2_H2O2Hi DT_V71E Chitikila_02 0.38 0.4092 102REB1_H2O2Hi rpd3 Fazzio01 0.38 0.4093 57NDD1_YPD snf2_rich_medium_experimentSudarsanam00 -0.38 0.4095 85FKH2_YPD hat1D_taf1-ts2Durant06 0.38 0.4097 103MCM1_YPD RPD3_haploid Hughes00 0.38 0.4097 76RLM1_YPD DT_Null Chitikila_02 -0.38 0.4103 52MCM1_YPD DT_V161E Chitikila_02 0.38 0.4103 72REB1_YPD gcn5 Huisinga04 -0.38 0.4104 136SKN7_H2O2HiH4_2-26 Sabet04 0.38 0.4104 92

PHO4_YPD RSC8 Mnaimneh_04 0.38 0.4105 72YAP7_H2O2Hi ISW1_ISW2 Hughes00 0.38 0.4107 141DAL82_RAPA htz1 Meneghini03 0.38 0.4108 51DIG1_Alpha ZDS1 Hughes00 0.38 0.411 59PUT3_H2O2Lo ume6_del Bernstein_00_affydeletions0.38 0.4113 82YAP7_H2O2Lo ZDS1 Hughes00 0.38 0.4113 150DIG1_Alpha DT_V161R_K Chitikila_02 0.38 0.4118 56RCS1_H2O2LoWT_TAF1_SPT3Huisinga04 0.38 0.4119 249OAF1_YPD Drxt1 Keogh05 -0.38 0.412 58SWI4_YPD hmr Meneghini03 -0.38 0.4122 152UME6_H2O2Hiarp8 Attikum04 -0.38 0.4122 69RPN4_H2O2LoTUP1_haploid Hughes00 -0.38 0.4122 98MCM1_YPD SIR2 Hughes00 -0.38 0.4122 76DAL82_SM hht2_K49141823GMartin04 0.38 0.4124 41STE12_Alpha SGF11 Ingvarsdottir05 -0.38 0.4125 96SOK2_BUT14 SIR4 Hughes00 -0.38 0.4126 72CBF1_SM SGF11 Ingvarsdottir05 -0.38 0.4128 232DAL82_SM esa1-414_taf1-ts2Durant06 0.38 0.4128 50NRG1_YPD 0.1%_MMS Attikum04 -0.38 0.4128 37HSF1_H2O2Hi DT_N69R Chitikila_02 0.38 0.4129 119RIM101_H2O2Loset1 Boa03 0.38 0.4129 54GCN4_RAPA isw2_rpd3_vs._rpd3Fazzio01 -0.38 0.413 155MSN4_RAPA hat2_vs._hat1Rosaleny05 0.38 0.413 53YAP6_H2O2Lo SAP30 Hughes00 -0.38 0.413 57STE12_Alpha SSN6_haploid Hughes00 -0.38 0.4131 109CIN5_H2O2Hi ume6 Fazzio01 0.38 0.4132 78SOK2_BUT14 SIR2 Hughes00 0.38 0.4133 72MCM1_YPD hmr Meneghini03 -0.38 0.4135 77SWI5_YPD YNG2 Krogan04 0.38 0.4137 97TYE7_YPD Drxt1 Keogh05 0.38 0.4137 56RPN4_H2O2LoDeaf3 Keogh05 0.38 0.4137 96REB1_YPD hda1_del Bernstein_00_affydeletions0.38 0.4138 138NRG1_H2O2HiDeaf3 Keogh05 0.38 0.4138 116OAF1_YPD DT_WT Chitikila_02 -0.38 0.4138 53MBP1_YPD H4_2-26 Sabet04 -0.38 0.4142 126RLM1_YPD WT_F182V Chitikila_02 -0.38 0.4143 46DIG1_Alpha ume6 Fazzio01 -0.38 0.4143 59GCN4_YPD WT_F182V Chitikila_02 -0.38 0.4143 58SWI5_YPD SWD2 Mnaimneh_04 0.38 0.4144 102YAP6_H2O2Lo HST3 Hughes00 0.38 0.4145 57CIN5_H2O2Hi DT_V71E Chitikila_02 -0.38 0.4147 79STP1_SM arp8_+_0.1%_MMS_vs._arp8Attikum04 0.38 0.4149 51GCR2_SM DT_V71R Chitikila_02 -0.38 0.415 54MSN2_H2O2HiSPT3 Ingvarsdottir05 0.38 0.415 69DAL82_SM WT_TAF1_SPT3Huisinga04 0.38 0.4152 53DAL82_RAPA H4_2-26 Sabet04 0.38 0.4154 53YAP1_YPD rpd3_c.i. Fazzio01 -0.38 0.4156 68DIG1_Alpha hat1D Durant06 -0.38 0.4156 43NRG1_YPD taf1-ts2_spt3_E240KHuisinga04 -0.38 0.4156 63FKH1_YPD taf1-ts2_25C Huisinga04 0.38 0.4157 129RPN4_H2O2LoWT_N69R Chitikila_02 -0.38 0.4159 95RTG3_RAPA esa1-414 Durant06 0.38 0.416 49MBP1_H2O2Hihos2_del Bernstein_00_affydeletions0.38 0.416 124

OAF1_YPD ubp10sir4 Orlandi04 0.38 0.416 34UME6_YPD ARD1 Hughes00 -0.38 0.4161 129DIG1_BUT14 SPT3 Ingvarsdottir05 0.38 0.4162 57MCM1_Alpha arp8 Attikum04 -0.38 0.4164 89RIM101_H2O2LoHAT2 Hughes00 0.38 0.4165 53STE12_BUT90 gcn5D_taf1-ts2Durant06 0.38 0.4165 69GCR2_SM spt3_E240K Huisinga04 -0.38 0.4168 43STP1_SM hht2K9131823GMartin04 -0.38 0.4168 53ROX1_YPD isw2_sin3_vs._sin3Fazzio01 -0.37 0.4169 67RTG3_RAPA htz1 Meneghini03 0.37 0.4169 50STE12_BUT14 SPT3 Ingvarsdottir05 0.37 0.4169 110YAP7_H2O2Hi UBP8 Hughes00 0.37 0.4171 139STE12_BUT14 sas3D Durant06 0.37 0.4172 98ACE2_YPD WT_WT Chitikila_02 -0.37 0.4172 74MBP1_YPD swi1_minimal_medium_experimentSudarsanam00 -0.37 0.4173 130ABF1_YPD set1 Boa03 -0.37 0.4174 263OAF1_YPD gcn5D_taf1-ts2Durant06 -0.37 0.4176 55CBF1_SM YAF9 Krogan04 0.37 0.4177 267MBP1_H2O2HiWT_F182V Chitikila_02 0.37 0.4177 97SKN7_YPD sap30_del Bernstein_00_affydeletions0.37 0.4178 55MSN4_RAPA WT_V71E Chitikila_02 -0.37 0.4182 41RLM1_YPD HAT2 Hughes00 0.37 0.4184 54DAL82_RAPA WT_N69R Chitikila_02 -0.37 0.4184 52NDD1_YPD hat2_vs._YPH250Rosaleny05 0.37 0.4185 81ABF1_YPD hpa2D_taf1-ts2Durant06 0.37 0.4186 210YAP6_YPD BUR6 Geisberg_01 -0.37 0.4186 87MSN4_H2O2HiDT_WT Chitikila_02 0.37 0.4187 68MCM1_Alpha Set1_del Bernstein02 -0.37 0.4187 105UME6_YPD WT_TAF1_SPT3Huisinga04 0.37 0.419 119PHO4_YPD rsc30_null Angus-Hill_01 0.37 0.4191 70MSN4_RAPA rpd3_H4KQ_v_H4KQSabet04 -0.37 0.4192 52PHO4_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 0.37 0.4195 57RLM1_YPD ino80 Attikum04 0.37 0.4196 40SWI4_YPD DT_V71R Chitikila_02 -0.37 0.4196 150HSF1_H2O2LoDT_N69R Chitikila_02 -0.37 0.4199 96UME6_H2O2Hisnf2_rich_medium_experimentSudarsanam00 0.37 0.4201 101RPN4_H2O2Lohht2_K914182327GMartin04 0.37 0.4201 88YAP1_YPD ZDS1 Hughes00 0.37 0.4204 72NRG1_H2O2HiYAF9 Krogan04 0.37 0.4204 115MGA1_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.37 0.4208 60HSF1_H2O2Hi spt3_E240K Huisinga04 0.37 0.421 98MCM1_YPD rpd3_H4KQ_v_H4KQSabet04 -0.37 0.421 72PHO4_YPD SSN6_haploid Hughes00 -0.37 0.4211 71DAL82_RAPA rsc30_null Angus-Hill_01 -0.37 0.4213 54TYE7_YPD ino80_del Mizuguch04 0.37 0.4214 56STE12_YPD swr1 Meneghini03 -0.37 0.4217 43GLN3_RAPA SWC6_(VPS71)Krogan04 0.37 0.4218 56UME6_H2O2HiWT_Null_L Chitikila_02 0.37 0.4219 92MGA1_YPD taf1-ts2_gcn5_KQLHuisinga04 -0.37 0.422 54YAP6_H2O2Hi SIR3 Hughes00 0.37 0.4222 78STP1_SM RPD3_haploid Hughes00 0.37 0.4223 67MCM1_YPD DT_V71E Chitikila_02 0.37 0.4223 70DAL82_SM MOT1-42 Dasgupta02 0.37 0.4225 55

SKN7_YPD IOC4 Hughes00 -0.37 0.4226 66STE12_YPD YNG2 Krogan04 -0.37 0.4227 51PHD1_BUT90 ZDS1 Hughes00 0.37 0.4229 101FKH1_YPD YAF9 Krogan04 -0.37 0.423 136FKH2_YPD DT_N69S Chitikila_02 0.37 0.423 110ROX1_YPD DT_V161R_L Chitikila_02 0.37 0.4231 65AFT2_H2O2Hi RPD3_haploid Hughes00 0.37 0.4231 61MBP1_H2O2Hi sin3_del Bernstein_00_affydeletions0.37 0.4232 124STP1_SM ARP4 Mnaimneh_04 -0.37 0.4234 68ASH1_BUT14 HAT2 Hughes00 0.37 0.4234 50AFT2_H2O2Lo HTZ1 Krogan04 -0.37 0.4237 85PHO4_YPD H3_1-28 Sabet04 0.37 0.4239 69MCM1_Alpha gcn5D Durant06 0.37 0.4241 84REB1_YPD sin3 Fazzio01 -0.37 0.4242 142TYE7_YPD spt3 Huisinga04 -0.37 0.4242 53RTG3_RAPA DT_N69S Chitikila_02 0.37 0.4242 47STP1_SM H3KQ Sabet04 -0.37 0.4244 67MCM1_Alpha sin3_del Bernstein_00_affydeletions-0.37 0.4246 101RCS1_H2O2LoHIR2 Hughes00 0.37 0.4247 256RIM101_H2O2LoDT_V71E Chitikila_02 0.37 0.4247 53PHO4_YPD WT_V71E Chitikila_02 0.37 0.4249 60XBP1_H2O2Lo swr1_del Mizuguch04 -0.37 0.425 68RTG3_RAPA isw2_sin3 Fazzio01 -0.37 0.4253 51RIM101_H2O2LoDrpd3 Keogh05 0.37 0.4253 50ROX1_YPD Dume1 Keogh05 -0.37 0.4254 63RIM101_H2O2Lotaf1-ts2_25C Huisinga04 -0.37 0.4254 48MGA1_YPD sas3D_taf1-ts2Durant06 -0.37 0.4254 53CIN5_H2O2Hi HIR2 Hughes00 0.37 0.4258 79XBP1_H2O2Lo gcn5D Durant06 0.37 0.4258 51REB1_YPD gcn5D_taf1-ts2Durant06 0.37 0.4259 137CIN5_H2O2Lo Dume1 Keogh05 0.37 0.4262 118REB1_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 0.37 0.4263 57GCR2_SM gcn5 Huisinga04 -0.37 0.4265 52UME6_H2O2HiYAF9 Krogan04 0.36 0.4266 92MSN4_H2O2HiISW2 Hughes00 -0.36 0.4268 68YAP7_H2O2Hi hat1D_taf1-ts2Durant06 0.36 0.4268 119PHD1_YPD esa1-414 Durant06 0.36 0.4269 56CIN5_H2O2Lo spt10 Eriksson05 0.36 0.4272 121STP1_SM TUP1_haploid Hughes00 -0.36 0.4274 65REB1_H2O2Hi taf1-ts2_GCN5Huisinga04 -0.36 0.4274 54ROX1_YPD Drpd3 Keogh05 -0.36 0.4276 63RPN4_H2O2LoH4_2-26 Sabet04 -0.36 0.4276 98MSN4_RAPA IES6 Hughes00 0.36 0.4277 52DAL82_RAPA SIR4 Hughes00 0.36 0.4278 55RTG3_RAPA arp8 Attikum04 0.36 0.4278 36FKH1_YPD sir4 Orlandi04 -0.36 0.4281 103RLM1_YPD gcn5 Huisinga04 -0.36 0.4283 52SUM1_YPD esa1-414_taf1-ts2Durant06 -0.36 0.4285 47GCN4_YPD gcn5D Durant06 0.36 0.4285 70SUT1_YPD Dsin3 Keogh05 -0.36 0.4287 59CIN5_H2O2Lo DT_N69R Chitikila_02 0.36 0.4292 119RLM1_YPD H3_1-28 Sabet04 -0.36 0.4293 50STE12_YPD SIR3 Hughes00 -0.36 0.4293 53

MGA1_YPD elp3D_taf1-ts2Durant06 -0.36 0.4294 48HSF1_H2O2Hi isw2 Fazzio01 0.36 0.4295 118SKN7_YPD SPT3 Ingvarsdottir05 -0.36 0.4296 54CBF1_SM spt3 Huisinga04 -0.36 0.4296 267YAP6_H2O2Hi MED2_haploid Hughes00 0.36 0.4296 78YAP7_H2O2Lo rpd3_c.i. Fazzio01 -0.36 0.4296 148ACE2_YPD Dsap30 Keogh05 0.36 0.4297 79AFT2_H2O2Hi WT Durant06 -0.36 0.4299 55ROX1_YPD rsc3-2 Angus-Hill_01 -0.36 0.43 67SWI6_YPD ISW1_ISW2 Hughes00 0.36 0.43 153RCS1_H2O2Hi MOT1-14 Dasgupta02 -0.36 0.4301 52RIM101_H2O2LoSIN3 Hughes00 -0.36 0.4302 53RLM1_YPD set1 Boa03 -0.36 0.4304 53YAP7_H2O2Hi SWC6_(VPS71)Krogan04 -0.36 0.4305 128DIG1_BUT14 SIR3 Hughes00 -0.36 0.4305 61NRG1_H2O2Hiume6_del Bernstein_00_affydeletions0.36 0.4309 112MSN4_RAPA ZDS1 Hughes00 0.36 0.4311 53TYE7_YPD ARP4 Mnaimneh_04 0.36 0.4315 56CBF1_SM UBP8 Ingvarsdottir05 -0.36 0.4315 251SWI4_YPD HST3 Hughes00 -0.36 0.4316 155MGA1_YPD hpa2D_taf1-ts2Durant06 -0.36 0.4317 44UME6_YPD isw2 Fazzio01 -0.36 0.4318 124GCN4_YPD WT_TAF1_SPT3Huisinga04 0.36 0.432 74GCN4_YPD isw2_rpd3 Fazzio01 0.36 0.4322 74NRG1_YPD esa1-414_taf1-ts2Durant06 -0.36 0.4322 51FKH2_H2O2Hi BUR6 Geisberg_01 0.36 0.4324 100AFT2_H2O2Lo SWR1 Krogan04 -0.36 0.4324 84YAP7_H2O2Hi DT_V71R Chitikila_02 0.36 0.4326 137REB1_YPD H4_2-26 Sabet04 0.36 0.4332 141GCR2_SM Dsin3 Keogh05 0.36 0.4332 47DAL82_RAPA isw2_ume6 Fazzio01 0.36 0.4333 54MSN2_H2O2Hihht2_K914182327GMartin04 0.36 0.4337 63RCS1_H2O2Hi arp8 Attikum04 -0.36 0.434 35TYE7_YPD ubp10 Orlandi04 -0.36 0.4342 38GLN3_RAPA hos3_del Bernstein_00_affydeletions0.36 0.4342 64REB1_YPD Drxt1 Keogh05 -0.36 0.4344 142YAP7_H2O2Lo isw2_sin3_vs._sin3Fazzio01 -0.36 0.4344 148MGA1_YPD taf1-ts2_spt3_E240KHuisinga04 0.36 0.4347 57MSN4_RAPA rsc3-2 Angus-Hill_01 -0.36 0.4348 53SKN7_H2O2LoDeaf3 Keogh05 0.36 0.4349 162MGA1_YPD gcn5D_taf1-ts2Durant06 -0.36 0.4349 55MBP1_H2O2Lohht2_K914182327GMartin04 0.36 0.4351 44ASH1_BUT14 MOT1-42 Dasgupta02 0.36 0.4352 50OAF1_YPD Drpd3 Keogh05 0.36 0.4352 54MCM1_YPD DT_V161R_L Chitikila_02 0.36 0.4355 71MBP1_H2O2HiSPT8 Ingvarsdottir05 -0.36 0.4357 123AFT2_H2O2Lo elp3D_taf1-ts2Durant06 0.36 0.4357 80DIG1_BUT14 gcn5 Huisinga04 -0.36 0.4357 62MCM1_YPD hos2_del Bernstein_00_affydeletions-0.36 0.4358 69YAP1_YPD H3_1-28 Sabet04 -0.36 0.4359 70RCS1_H2O2Hi hda1_del Bernstein_00_affydeletions0.36 0.4361 45MCM1_Alpha rpd3 Fazzio01 0.36 0.4363 104CIN5_YPD Drpd3 Keogh05 0.35 0.4366 137

REB1_H2O2Hi RSC8 Mnaimneh_04 -0.35 0.4368 59YAP6_YPD gcn5_KQL Huisinga04 0.35 0.4369 73HAP1_YPD Dsin3 Keogh05 0.35 0.4369 122MGA1_YPD snf2_rich_medium_experimentSudarsanam00 0.35 0.4371 62UME6_H2O2HiHda1_del Bernstein02 -0.35 0.4372 99REB1_YPD taf1-ts2_25C Huisinga04 0.35 0.4374 134DIG1_Alpha SIR4 Hughes00 -0.35 0.4374 60DIG1_BUT14 rsc3-2 Angus-Hill_01 -0.35 0.4374 60STE12_YPD SIR4 Hughes00 -0.35 0.4376 54SWI5_YPD WT_Null_L Chitikila_02 -0.35 0.4376 92FKH2_YPD PCH1 Hughes00 0.35 0.438 120HSF1_H2O2LoDsin3 Keogh05 0.35 0.4381 83MGA1_YPD SWR1 Krogan04 -0.35 0.4382 59RTG3_RAPA HIR2 Hughes00 0.35 0.4383 52MSN2_H2O2HiHAT2 Hughes00 0.35 0.4383 76RCS1_H2O2Hi SWR1 Krogan04 -0.35 0.4387 47STE12_BUT90 ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.35 0.4387 67GLN3_RAPA MED2_haploid Hughes00 -0.35 0.4388 67SUM1_YPD isw2_sin3_vs._sin3Fazzio01 0.35 0.4389 59HSF1_H2O2Hi DT_V71E Chitikila_02 0.35 0.439 122FKH2_H2O2Hi elp3D Durant06 0.35 0.4391 81PUT3_H2O2Lo Dsds3 Keogh05 -0.35 0.4392 80DIG1_Alpha HTZ1 Krogan04 0.35 0.4392 56OAF1_YPD hpa2D_taf1-ts2Durant06 -0.35 0.4392 47ROX1_YPD WT_TAF1_SPT3Huisinga04 -0.35 0.4393 63CIN5_H2O2Hi Drxt2 Keogh05 -0.35 0.4393 76CIN5_YPD ISW2 Hughes00 -0.35 0.4396 150MSN4_RAPA TUP1_haploid Hughes00 0.35 0.4396 52CBF1_SM SWR1 Krogan04 0.35 0.4397 241NRG1_H2O2HiSGF11 Ingvarsdottir05 0.35 0.4399 105MCM1_Alpha HTZ1 Krogan04 0.35 0.4399 99RIM101_H2O2LoARD1 Hughes00 -0.35 0.44 53PHD1_YPD rsc30_null Angus-Hill_01 -0.35 0.4408 65RCS1_H2O2Hi DT_V71E Chitikila_02 0.35 0.4408 48HAP1_YPD Dsap30 Keogh05 -0.35 0.441 135PUT3_H2O2Lo isw2_rpd3_vs._rpd3Fazzio01 -0.35 0.4412 86XBP1_H2O2Lo htz1_del Mizuguch04 0.35 0.4412 68YAP6_YPD hht2K9131823GMartin04 0.35 0.4416 62NRG1_YPD Drco1 Keogh05 0.35 0.4419 65SUT1_YPD UBP8 Ingvarsdottir05 0.35 0.4422 61MBP1_H2O2Hi taf1-ts2_25C Huisinga04 0.35 0.4422 121NRG1_YPD SIR4 Hughes00 -0.35 0.4422 72YAP7_H2O2Hi VID21 Krogan04 0.35 0.4424 134RTG3_RAPA rsc30_null Angus-Hill_01 -0.35 0.4425 51YAP6_H2O2Lo arp8 Attikum04 0.35 0.4427 38ABF1_YPD Drxt2 Keogh05 0.35 0.4429 256MSN4_RAPA WT_Null_L Chitikila_02 -0.35 0.4429 48GCN4_YPD EPL1 Mnaimneh_04 0.35 0.4429 75YAP6_H2O2Hi EPL1 Mnaimneh_04 0.35 0.443 79CIN5_H2O2Lo WT_V161R_L Chitikila_02 -0.35 0.4431 123AFT2_H2O2Lo MOT1-42 Dasgupta02 0.35 0.4432 98YAP6_H2O2Lo ino80_del Mizuguch04 -0.35 0.4432 59HSF1_H2O2LoISW2 Hughes00 -0.35 0.4433 99

NDD1_YPD Dume1 Keogh05 -0.35 0.4434 80SUM1_YPD Drxt1 Keogh05 0.35 0.4435 57REB1_H2O2Hi taf1-ts2_25C Huisinga04 0.35 0.4435 55RPN4_H2O2LoDrxt2 Keogh05 0.35 0.4435 99TYE7_YPD HAT2 Hughes00 -0.35 0.4436 56ROX1_YPD WT_Null_L Chitikila_02 0.35 0.4437 64RIM101_H2O2LoWT_Null_L Chitikila_02 -0.35 0.4437 49RCS1_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 0.35 0.4438 50RTG3_RAPA Dsap30 Keogh05 -0.35 0.444 49OAF1_YPD WT_N69S Chitikila_02 -0.35 0.4442 50DAL82_SM isw2_ume6 Fazzio01 -0.35 0.4444 50UME6_YPD hat2_vs._hat1Rosaleny05 -0.35 0.4448 123MCM1_YPD snf2_rich_medium_experimentSudarsanam00 -0.35 0.4448 77UME6_H2O2Hihat1D Durant06 -0.35 0.4449 73AFT2_H2O2Lo spt10_del Xu05 0.35 0.4449 98REB1_YPD MED2_haploid Hughes00 0.35 0.445 144DAL82_SM WT_TAF1_GCN5Huisinga04 -0.35 0.4451 54MCM1_YPD swi1_rich_medium_experimentSudarsanam00 -0.35 0.4451 77MBP1_H2O2Lo_SWC2_(VPS72)Krogan04 -0.35 0.4452 54MCM1_YPD EAF7 Krogan04 0.35 0.4452 72SKN7_YPD Deaf3 Keogh05 0.35 0.4454 56CIN5_YPD RSC8 Mnaimneh_04 0.35 0.4454 150UME6_YPD DT_V71E Chitikila_02 0.35 0.4459 122STE12_Alpha hht2K9131823GMartin04 -0.35 0.4459 90TYE7_YPD sap30_del Bernstein_00_affydeletions-0.35 0.4461 54YAP7_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 0.35 0.4461 137OAF1_YPD Dume1 Keogh05 -0.35 0.4461 52CBF1_SM elp3D Durant06 -0.35 0.4463 236CBF1_SM hpa2D Durant06 0.34 0.447 213AFT2_H2O2Hi DT_N69S Chitikila_02 -0.34 0.4471 54HSF1_H2O2LoDdep1 Keogh05 0.34 0.4471 95REB1_H2O2Hi gcn5 Huisinga04 -0.34 0.4472 56HSF1_H2O2Hi ISW1_ISW2 Hughes00 0.34 0.4473 123NRG1_H2O2HiDT_V71E Chitikila_02 -0.34 0.4474 118REB1_YPD sir4 Orlandi04 0.34 0.4475 108SWI4_YPD ino80_del Mizuguch04 -0.34 0.4478 156STP1_SM DM_vs._YPH250Rosaleny05 -0.34 0.4479 63PUT3_H2O2Lo hht2_K49141823GMartin04 -0.34 0.4479 66RCS1_H2O2LoISW2 Hughes00 -0.34 0.448 257HSF1_H2O2LoSet1_del Bernstein02 0.34 0.4485 101YAP6_H2O2Lo RAD6_haploid Hughes00 -0.34 0.4485 57REB1_YPD isw2 Fazzio01 0.34 0.4486 142MCM1_Alpha WT_TAF1_SPT3Huisinga04 0.34 0.4486 103HAP4_YPD Deaf3 Keogh05 -0.34 0.4486 58CIN5_H2O2Hi ZDS1 Hughes00 -0.34 0.4487 78MBP1_H2O2Hi snf2_rich_medium_experimentSudarsanam00 -0.34 0.4488 132STE12_BUT14 rsc3-2 Angus-Hill_01 0.34 0.4489 122STE12_YPD SAP30 Hughes00 0.34 0.449 52OAF1_YPD sir4 Orlandi04 0.34 0.449 33GCR2_SM HAT2 Hughes00 -0.34 0.4492 54FKH1_YPD rsc3-2 Angus-Hill_01 -0.34 0.4493 139PHO4_YPD ARD1 Hughes00 0.34 0.4495 70ROX1_YPD hht2_K914182327GMartin04 -0.34 0.4495 41

HSF1_H2O2Lodelta_ssd1 Kaeberlein04 0.34 0.4497 101STE12_YPD gcn5D_taf1-ts2Durant06 0.34 0.4498 42CIN5_H2O2Hi IOC4 Hughes00 0.34 0.4505 78XBP1_H2O2Lo SIN3 Hughes00 -0.34 0.4505 67XBP1_H2O2Lo WT_F182V Chitikila_02 -0.34 0.4505 52STP1_SM HDA1 Hughes00 0.34 0.4506 67SUM1_YPD SIR3 Hughes00 -0.34 0.4507 58SWI6_YPD swr1_del Mizuguch04 0.34 0.4507 151MCM1_Alpha set1 Boa03 -0.34 0.4515 106DIG1_BUT14 ARD1 Hughes00 -0.34 0.4515 63YAP1_YPD Drco1 Keogh05 0.34 0.4517 69RPN4_H2O2LoDrxt1 Keogh05 -0.34 0.4517 98GCN4_SM WT Durant06 -0.34 0.4518 175FKH2_YPD Dume1 Keogh05 -0.34 0.4518 111STE12_YPD WT Durant06 0.34 0.4522 49SWI6_YPD Dsin3 Keogh05 0.34 0.4522 127MSN4_RAPA hda1_del Bernstein_00_affydeletions-0.34 0.4524 50MSN4_RAPA sas3D Durant06 -0.34 0.4526 40GCR2_SM hht2_K4914182327GMartin04 -0.34 0.4527 46GLN3_RAPA hmr Meneghini03 -0.34 0.4527 63MBP1_H2O2LoDsds3 Keogh05 0.34 0.4527 53HAP4_YPD Dsds3 Keogh05 -0.34 0.4528 61FKH2_H2O2Hi DT_N69R Chitikila_02 0.34 0.4529 94STE12_BUT14 set1 Boa03 -0.34 0.453 126MCM1_Alpha hht2_K914182327GMartin04 0.34 0.4532 88RLM1_YPD sin3 Fazzio01 -0.34 0.4535 54STP1_SM MOT1-14 Dasgupta02 0.34 0.4536 67TYE7_YPD HTZ1 Krogan04 -0.34 0.4539 50CIN5_YPD HAT2 Hughes00 -0.34 0.4539 147STP1_SM MOT1-42 Dasgupta02 0.34 0.454 67NRG1_YPD rsc30_null Angus-Hill_01 -0.34 0.454 70ROX1_YPD hht2_K4G Martin04 0.34 0.4545 43NRG1_H2O2HiSIN3 Hughes00 -0.34 0.4546 126ASH1_BUT14 WT_WT Chitikila_02 -0.34 0.4548 49DIG1_BUT14 Drpd3 Keogh05 -0.34 0.455 60NRG1_YPD ubp10 Orlandi04 0.34 0.4551 22RTG3_RAPA SAP30 Hughes00 0.34 0.4552 52MBP1_H2O2LoHAT2 Hughes00 0.34 0.4552 57SKN7_H2O2Hi hht2_K914182327GMartin04 0.34 0.4553 73RPN4_H2O2LoDsap30 Keogh05 -0.34 0.4555 99MBP1_YPD UBP8 Hughes00 0.34 0.4556 129CBF1_SM hmr Meneghini03 0.34 0.4557 269RTG3_RAPA sir4 Orlandi04 0.34 0.456 36UME6_H2O2Hihtz1_sir2 Meneghini03 0.34 0.4561 99RCS1_H2O2Hi delta_ssd1 Kaeberlein04 0.34 0.4563 52UME6_YPD SIR2 Hughes00 0.34 0.4565 129FKH1_YPD Dume1 Keogh05 -0.34 0.4565 132DIG1_BUT14 hht2_K27G Martin04 -0.34 0.4566 53UME6_H2O2HiSWR1 Krogan04 0.34 0.4567 87MSN4_RAPA ARD1 Hughes00 0.34 0.4568 52MSN2_H2O2Hiswr1_del Mizuguch04 0.34 0.4568 78MCM1_Alpha elp3D_taf1-ts2Durant06 0.34 0.4569 73UME6_H2O2Hiswi1_rich_medium_experimentSudarsanam00 0.34 0.457 102

FKH2_YPD UBP8 Ingvarsdottir05 -0.33 0.4571 114DAL82_RAPA ARP4 Mnaimneh_04 0.33 0.4572 56FKH2_YPD spt3 Huisinga04 -0.33 0.4572 117RLM1_YPD swr1_del Mizuguch04 0.33 0.4575 55REB1_YPD SIR2 Hughes00 -0.33 0.4576 142SWI6_YPD Set1_del Bernstein02 -0.33 0.4577 151HSF1_H2O2Hi ISW1 Hughes00 0.33 0.4582 121ABF1_YPD Dsds3 Keogh05 0.33 0.4584 248ROX1_YPD DT_V161R_K Chitikila_02 0.33 0.4584 67SKN7_YPD snf2_rich_medium_experimentSudarsanam00 -0.33 0.4586 67YAP7_H2O2Lo hos2_del Bernstein_00_affydeletions-0.33 0.4586 144GCN4_SM hht2_K27G Martin04 0.33 0.4588 161PHD1_BUT90 WT_WT Chitikila_02 -0.33 0.4588 102GLN3_RAPA DT_N69S Chitikila_02 -0.33 0.4589 60MSN4_RAPA H3_1-28 Sabet04 -0.33 0.4592 52CIN5_YPD HTZ1 Krogan04 -0.33 0.4593 139FKH2_YPD EAF5 Krogan04 0.33 0.4593 106ABF1_YPD WT_WT Chitikila_02 0.33 0.4594 252NRG1_H2O2Hihht2_K4914182327GMartin04 0.33 0.4594 89AFT2_H2O2Hi WT_WT Chitikila_02 0.33 0.4598 57HSF1_H2O2Lospt3_E240K Huisinga04 0.33 0.4599 78STE12_YPD DT_V71E Chitikila_02 -0.33 0.46 47YAP1_YPD MOT1-42 Dasgupta02 -0.33 0.46 71GCN4_RAPA hat1D Durant06 -0.33 0.4602 121PHD1_YPD taf1-ts2_GCN5Huisinga04 -0.33 0.4603 61FKH1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.33 0.4606 111FKH1_YPD swi1_rich_medium_experimentSudarsanam00 -0.33 0.4607 142DAL82_SM hat1D_taf1-ts2Durant06 -0.33 0.4612 43GCN4_YPD MOT1-14 Dasgupta02 0.33 0.4613 75STP1_SM hmr Meneghini03 -0.33 0.4615 65REB1_H2O2Hi gcn5D_taf1-ts2Durant06 0.33 0.4617 53PHD1_YPD taf1-ts2 Durant06 -0.33 0.4619 65PHD1_BUT90 DT_N69R Chitikila_02 0.33 0.4619 98GCR2_SM PCH1 Hughes00 0.33 0.4622 54STE12_YPD Deaf3 Keogh05 0.33 0.4626 51NRG1_H2O2HiDT_V161R_K Chitikila_02 0.33 0.4626 118STE12_BUT90 DT_N69R Chitikila_02 -0.33 0.4627 71PHO4_YPD UBP8 Ingvarsdottir05 -0.33 0.4628 67YAP1_YPD YNG2 Mnaimneh_04 -0.33 0.4631 72STP1_SM WT_Null_K Chitikila_02 0.33 0.4631 65RCS1_H2O2Losir2 Meneghini03 -0.33 0.4631 249SWI5_YPD DT_V71E Chitikila_02 -0.33 0.4632 92SKN7_H2O2LoSGF11 Ingvarsdottir05 0.33 0.4635 158RTG3_RAPA ubp10sir4 Orlandi04 -0.33 0.4638 36MBP1_H2O2Lohht2_K4G Martin04 0.33 0.4639 45TYE7_YPD EPL1 Mnaimneh_04 -0.33 0.464 56REB1_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 0.33 0.4641 49SKN7_H2O2Hi PCH1 Hughes00 0.33 0.4641 96MGA1_YPD spt10 Eriksson05 -0.33 0.4642 62ABF1_YPD sir2 Meneghini03 -0.33 0.4644 262STE12_BUT90 IOC4 Hughes00 -0.33 0.4648 77REB1_H2O2Hi ubp10sir4 Orlandi04 0.33 0.4654 44STE12_YPD ubp10sir4 Orlandi04 -0.33 0.4656 31

SUT1_YPD hpa2D Durant06 0.33 0.4656 49AFT2_H2O2Hi htz1_hmr Meneghini03 0.33 0.466 61CIN5_H2O2Lo hht2_K27G Martin04 -0.33 0.466 83PUT3_H2O2Lo _SWC2_(VPS72)Krogan04 0.33 0.466 82DIG1_BUT14 EAF7 Krogan04 0.33 0.4661 61YAP6_H2O2Hi Dume1 Keogh05 -0.33 0.4662 69MBP1_H2O2LoDdep1 Keogh05 0.33 0.4664 54RCS1_H2O2Lotaf1-ts2_gcn5 Huisinga04 0.33 0.4665 241DAL81_RAPA Deaf3 Keogh05 0.33 0.467 86HAP4_YPD rsc30_null Angus-Hill_01 0.33 0.4672 65REB1_YPD isw2_sin3 Fazzio01 -0.33 0.4673 142MSN4_H2O2HiDrxt1 Keogh05 -0.33 0.4673 70DAL82_SM sin3_del Bernstein_00_affydeletions-0.33 0.4674 48CIN5_H2O2Hi _SWC2_(VPS72)Krogan04 -0.33 0.4675 75GCN4_YPD taf1-ts2_gcn5 Huisinga04 0.33 0.4675 73UME6_H2O2Hirsc30_null Angus-Hill_01 -0.33 0.4676 101PHD1_YPD SAP30 Hughes00 0.33 0.4677 66MBP1_H2O2LoDT_V161R_K Chitikila_02 -0.33 0.4677 55PHO4_YPD set1 Boa03 0.32 0.4678 70YAP6_YPD hat1_vs.YPH250Rosaleny05 0.32 0.4681 85UME6_H2O2HiSPT8 Ingvarsdottir05 0.32 0.4683 92STP1_SM sir2 Meneghini03 -0.32 0.4685 65MSN4_RAPA ubp10 Orlandi04 0.32 0.4685 23GLN3_RAPA SAP30 Hughes00 0.32 0.4686 67REB1_YPD isw2_rpd3_vs._rpd3Fazzio01 0.32 0.4687 142ABF1_YPD ISW1 Hughes00 0.32 0.469 264DAL82_RAPA 0.1%_MMS Attikum04 0.32 0.469 43RPN4_H2O2LoSWD2 Mnaimneh_04 0.32 0.4691 100RLM1_YPD hht2_K4G Martin04 -0.32 0.4694 42TYE7_YPD YAF9 Krogan04 -0.32 0.4695 55STE12_Alpha WT_V71R Chitikila_02 0.32 0.4695 100FKH1_YPD DT_V161E Chitikila_02 0.32 0.4695 132ROX1_YPD SWR1 Krogan04 -0.32 0.4698 65CBF1_SM YNG2 Krogan04 0.32 0.4698 262SKN7_YPD BUR6 Geisberg_01 0.32 0.4702 63RPN4_H2O2LoEAF5 Krogan04 0.32 0.4705 94NDD1_YPD arp8 Attikum04 0.32 0.4705 72GCN4_RAPA Hda1_del Bernstein02 0.32 0.4706 159GLN3_RAPA UBP8 Ingvarsdottir05 -0.32 0.471 65CBF1_SM spt3_E240K Huisinga04 0.32 0.4711 253PHD1_YPD rpd3_H3dN_v_H3dNSabet04 0.32 0.4712 62UME6_YPD hat1_vs.YPH250Rosaleny05 0.32 0.4712 124AFT2_H2O2Hi swr1 Meneghini03 -0.32 0.4712 47GCN4_RAPA delta_ssd1 Kaeberlein04 0.32 0.4713 159SKN7_H2O2HiDdep1 Keogh05 0.32 0.4715 94STP1_SM isw2_rpd3_vs._rpd3Fazzio01 0.32 0.4716 67RCS1_H2O2Hi sir4 Orlandi04 -0.32 0.4716 28UME6_H2O2HiDT_WT Chitikila_02 -0.32 0.4718 94HAP4_YPD hht2_K4914182327GMartin04 -0.32 0.4718 54YAP6_YPD WT_V161E Chitikila_02 0.32 0.4719 85STE12_YPD spt10_del Xu05 -0.32 0.472 51MSN4_RAPA hat2_vs._YPH250Rosaleny05 0.32 0.472 53MCM1_Alpha hat1_vs.YPH250Rosaleny05 -0.32 0.472 100

STE12_BUT14 EAF7 Krogan04 0.32 0.472 119ASH1_BUT14 Dsin3 Keogh05 0.32 0.4721 37SUT1_YPD taf1-ts2 Durant06 0.32 0.4722 69DIG1_Alpha SPT3 Ingvarsdottir05 -0.32 0.4722 56STE12_Alpha sir4 Orlandi04 -0.32 0.4723 74STE12_BUT14 WT_V161R_L Chitikila_02 -0.32 0.4723 122PUT3_H2O2Lo SIR3 Hughes00 0.32 0.4725 88ABF1_YPD hht2_K27G Martin04 0.32 0.4732 234DIG1_Alpha esa1-414 Durant06 -0.32 0.4732 56PHO4_YPD HST3 Hughes00 -0.32 0.4736 71STP1_SM sin3 Fazzio01 -0.32 0.4739 67STP1_SM hht2_K27G Martin04 -0.32 0.474 54CIN5_H2O2Hi sas3D Durant06 -0.32 0.4741 51RTG3_RAPA rpd3 Fazzio01 -0.32 0.4745 51STE12_BUT90 SWC6_(VPS71)Krogan04 0.32 0.4746 75GCN4_SM Hda1_del Bernstein02 0.32 0.4747 188DIG1_Alpha DT_V71R Chitikila_02 -0.32 0.4747 56PHD1_YPD Deaf3 Keogh05 0.32 0.4749 59DAL82_SM Drxt1 Keogh05 -0.32 0.4749 52GCN4_YPD Ddep1 Keogh05 0.32 0.4749 69STE12_BUT14 H3_1-28 Sabet04 -0.32 0.4752 122PHD1_BUT90 WT_TAF1_SPT3Huisinga04 0.32 0.4752 103HSF1_H2O2Hi isw2_ume6 Fazzio01 0.32 0.4753 119HAP1_YPD gcn5 Huisinga04 -0.32 0.4754 134UME6_H2O2Hihtz1 Meneghini03 0.32 0.476 96OAF1_YPD isw2_ume6 Fazzio01 -0.32 0.476 56RTG3_RAPA htz1_del Mizuguch04 0.32 0.4765 52RCS1_H2O2LoWT_WT Chitikila_02 0.32 0.4765 243SKN7_YPD SIR2 Hughes00 -0.32 0.4766 66TYE7_YPD hpa2D_taf1-ts2Durant06 0.32 0.4767 47RTG3_RAPA ISW1_ISW2 Hughes00 0.32 0.4768 51OAF1_YPD spt3_E240K Huisinga04 -0.32 0.4768 50GLN3_RAPA hht2K9131823GMartin04 0.32 0.4769 51GLN3_RAPA YAF9 Krogan04 0.32 0.477 64SUT1_YPD RAD6_haploid Hughes00 -0.32 0.4771 69SWI6_YPD hos2_del Bernstein_00_affydeletions0.32 0.4772 144GCN4_SM spt10_del Xu05 -0.32 0.4772 188FKH1_YPD DT_V71E Chitikila_02 -0.32 0.4775 135DAL82_SM spt10 Eriksson05 -0.32 0.4776 53DAL82_RAPA DT_V71R Chitikila_02 0.32 0.4777 53MSN4_RAPA swr1 Meneghini03 -0.32 0.4777 42SKN7_YPD isw2_sin3 Fazzio01 -0.32 0.4781 63PHO4_YPD WT_Null_L Chitikila_02 0.32 0.4786 68MBP1_YPD SGF11 Ingvarsdottir05 -0.31 0.4787 105YAP6_H2O2Lo WT_WT Chitikila_02 -0.31 0.4788 53RCS1_H2O2Hi htz1_hmr Meneghini03 0.31 0.4789 50RPN4_H2O2Loisw2_c.i._rpd3_c.i.Fazzio01 -0.31 0.4789 96MSN4_RAPA isw2 Fazzio01 -0.31 0.4792 53NRG1_H2O2Hirsc30_null Angus-Hill_01 0.31 0.4792 122ACE2_YPD Deaf3 Keogh05 0.31 0.4793 77ROX1_YPD 0.1%_MMS Attikum04 -0.31 0.4794 45MBP1_H2O2Loesa1-414 Durant06 0.31 0.4794 55FKH2_H2O2Hi WT_F182V Chitikila_02 0.31 0.4795 85

DAL82_SM SPT8 Ingvarsdottir05 -0.31 0.4796 42FKH2_H2O2Hi Dume1 Keogh05 0.31 0.4796 101UME6_H2O2HiWT_WT Chitikila_02 -0.31 0.4799 93YAP6_H2O2Hi WT_WT Chitikila_02 0.31 0.48 75SUT1_YPD Dsap30 Keogh05 -0.31 0.4801 67DAL82_RAPA htz1_sir2 Meneghini03 0.31 0.4802 52RCS1_H2O2LoHda1_del Bernstein02 0.31 0.4804 252MBP1_YPD SSN6_haploid Hughes00 -0.31 0.4805 129DIG1_Alpha hda1_del Bernstein_00_affydeletions-0.31 0.4808 52SWI5_YPD HDA1 Hughes00 0.31 0.4809 99SKN7_YPD isw2_c.i. Fazzio01 -0.31 0.481 63ACE2_YPD swi1_rich_medium_experimentSudarsanam00 0.31 0.481 80OAF1_YPD YNG2 Krogan04 0.31 0.481 55GLN3_RAPA htz1_hmr Meneghini03 -0.31 0.4811 65MCM1_Alpha MOT1-42 Dasgupta02 0.31 0.4813 106PHD1_YPD hat1D_taf1-ts2Durant06 -0.31 0.4814 52YAP6_H2O2Hi hht2_K4G Martin04 -0.31 0.4814 48AFT2_H2O2Lo DT_V71E Chitikila_02 -0.31 0.4817 97SKN7_H2O2HiRpd3_del Bernstein02 -0.31 0.4819 96SWI5_YPD Rpd3_del Bernstein02 0.31 0.4822 99CBF1_SM hat2_vs._YPH250Rosaleny05 0.31 0.4822 256RCS1_H2O2Hi HAT2 Hughes00 0.31 0.4822 52RCS1_H2O2Hi isw2 Fazzio01 -0.31 0.4824 50DIG1_Alpha set1 Boa03 0.31 0.4824 58PUT3_H2O2Lo gcn5D Durant06 0.31 0.4826 71MSN2_H2O2HiPCH1 Hughes00 -0.31 0.4827 76SOK2_BUT14 swr1 Meneghini03 -0.31 0.4827 57MBP1_H2O2Hi spt10 Eriksson05 -0.31 0.4829 133MSN4_H2O2Hihos3_del Bernstein_00_affydeletions0.31 0.483 63AFT2_H2O2Lo SGF11 Ingvarsdottir05 0.31 0.4832 82OAF1_YPD WT_WT Chitikila_02 -0.31 0.4832 53ASH1_BUT14 swr1 Meneghini03 0.31 0.4833 40FKH1_YPD H3KQ Sabet04 -0.31 0.4833 138RLM1_YPD taf1-ts2_gcn5 Huisinga04 0.31 0.4835 53SKN7_YPD DT_V161R_L Chitikila_02 0.31 0.4835 63YAP7_H2O2Lo Deaf3 Keogh05 0.31 0.4835 133HAP4_YPD sas3D Durant06 0.31 0.4835 56PHD1_YPD HIR2 Hughes00 0.31 0.4839 65CIN5_YPD WT_WT Chitikila_02 -0.31 0.4839 147RTG3_RAPA Drco1 Keogh05 0.31 0.4839 47DIG1_BUT14 hpa2D_taf1-ts2Durant06 0.31 0.4839 49STE12_BUT90 Rpd3_del Bernstein02 -0.31 0.484 76REB1_YPD hht2K9131823GMartin04 0.31 0.4841 129MSN4_RAPA SSN6_haploid Hughes00 -0.31 0.4841 52MCM1_YPD TAF2 Mnaimneh_04 0.31 0.4841 77OAF1_YPD SIR4 Hughes00 -0.31 0.4843 59SKN7_YPD ISW1_ISW2 Hughes00 0.31 0.4845 65DAL82_SM IES6 Hughes00 0.31 0.4848 55SWI4_YPD Dsin3 Keogh05 0.31 0.4849 130ACE2_YPD WT_Null_L Chitikila_02 0.31 0.4852 76MBP1_YPD arp8 Attikum04 0.31 0.4852 109SUM1_YPD EAF5 Krogan04 -0.31 0.4854 51STE12_BUT14 hht2_K27G Martin04 -0.31 0.4854 107

YAP1_YPD hpa2D Durant06 0.31 0.4855 59YAP1_YPD Drxt2 Keogh05 0.31 0.4857 69CBF1_SM hht2_K49141823GMartin04 0.31 0.4857 225STP1_SM SWC6_(VPS71)Krogan04 0.31 0.4857 57RIM101_H2O2LoWT_TAF1_SPT3Huisinga04 -0.31 0.4859 51XBP1_H2O2Lo arp8 Attikum04 0.31 0.4861 43HAP4_YPD SPT3 Ingvarsdottir05 -0.31 0.4862 57GCN4_YPD EAF5 Krogan04 -0.31 0.4866 66CIN5_H2O2Hi DT_Null Chitikila_02 -0.31 0.4867 80AFT2_H2O2Hi SIR1 Hughes00 0.31 0.4869 61STP1_SM DT_V71R Chitikila_02 0.31 0.487 65HAP1_YPD sin3_del Bernstein_00_affydeletions0.31 0.4871 135YAP6_YPD H3_1-28 Sabet04 0.31 0.4874 82RPN4_H2O2Loubp10 Orlandi04 -0.31 0.4876 78RLM1_YPD SIR3 Hughes00 0.31 0.4877 55NRG1_YPD rpd3_del Sabet04 0.31 0.4878 60SWI4_YPD Ddep1 Keogh05 0.31 0.488 149PHO4_YPD YAF9 Krogan04 -0.31 0.4881 69FKH2_H2O2Hi hat1D Durant06 0.31 0.4881 75YAP7_H2O2Hi WT_V71R Chitikila_02 -0.31 0.4881 131RCS1_H2O2Hi sin3_del Bernstein_00_affydeletions-0.31 0.4882 46YAP7_H2O2Hi hat2_vs._hat1Rosaleny05 -0.31 0.4882 140RCS1_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 0.31 0.4883 48MCM1_Alpha HST3 Hughes00 -0.31 0.4883 106RCS1_H2O2Hi htz1_sir2 Meneghini03 0.31 0.4885 50DIG1_Alpha DM_vs._YPH250Rosaleny05 -0.31 0.4885 54MSN4_RAPA WT_V161R_K Chitikila_02 0.31 0.4886 49MBP1_H2O2LoH4_2-26 Sabet04 -0.31 0.4886 56CIN5_YPD DT_WT Chitikila_02 -0.31 0.4888 140MBP1_YPD rpd3_H3dN_v_H3dNSabet04 -0.31 0.4888 126DIG1_BUT14 SWC6_(VPS71)Krogan04 0.31 0.4889 60XBP1_H2O2Lo IOC4 Hughes00 -0.31 0.4892 67YAP7_H2O2Lo DT_V161R_K Chitikila_02 0.31 0.4893 147MCM1_YPD arp8 Attikum04 -0.31 0.4893 58RPN4_H2O2Losir2 Meneghini03 0.31 0.4895 98STE12_BUT14 SIR1 Hughes00 0.31 0.4895 128UME6_H2O2Hiino80_del Mizuguch04 -0.31 0.4897 102TYE7_YPD _SWC2_(VPS72)Krogan04 0.3 0.4899 53FKH2_H2O2Hi DT_V161E Chitikila_02 0.3 0.4899 97MCM1_Alpha DT_V161E Chitikila_02 0.3 0.4902 103DIG1_Alpha WT_WT Chitikila_02 0.3 0.4903 55OAF1_YPD spt3 Huisinga04 -0.3 0.4903 57REB1_YPD SPT8 Ingvarsdottir05 0.3 0.4905 128HSF1_H2O2Hi Dsap30 Keogh05 0.3 0.4905 115SWI4_YPD H4_2-26 Sabet04 0.3 0.4907 151SKN7_YPD taf1-ts2_spt3 Huisinga04 -0.3 0.4908 65GCN4_YPD set1 Boa03 0.3 0.4909 75TYE7_YPD ISW1_ISW2 Hughes00 -0.3 0.491 56RLM1_YPD hht2_K914182327GMartin04 -0.3 0.4915 42ROX1_YPD isw2 Fazzio01 0.3 0.4915 67PHD1_BUT90 SWD2 Mnaimneh_04 0.3 0.4917 106SUT1_YPD rsc3-2 Angus-Hill_01 0.3 0.4918 69DIG1_Alpha DT_Null Chitikila_02 0.3 0.4918 54

REB1_YPD UBP8 Hughes00 -0.3 0.4919 143GCN4_RAPA set1 Boa03 0.3 0.4919 156HAP4_YPD hat2_vs._hat1Rosaleny05 0.3 0.4921 62STE12_YPD esa1-414 Durant06 0.3 0.4922 48PHD1_BUT90 htz1_del Mizuguch04 -0.3 0.4922 105PHD1_YPD sir4 Orlandi04 0.3 0.4924 34REB1_H2O2Hi hat2_vs._YPH250Rosaleny05 -0.3 0.4925 55SWI5_YPD hht2_K4914182327GMartin04 0.3 0.4928 81SOK2_BUT14 isw2_sin3_vs._sin3Fazzio01 0.3 0.4928 71SWI6_YPD Dpho23 Keogh05 0.3 0.4929 152MSN4_H2O2Hiisw2_c.i. Fazzio01 -0.3 0.4931 68PUT3_H2O2Lo HST3 Hughes00 -0.3 0.4931 86GCR2_SM Deaf3 Keogh05 0.3 0.4932 50STE12_BUT90 hat2_vs._hat1Rosaleny05 0.3 0.4932 75REB1_YPD WT_F182V Chitikila_02 0.3 0.4933 117MBP1_YPD SPT8 Ingvarsdottir05 -0.3 0.4935 123GCR2_SM SIR4 Hughes00 0.3 0.4936 54UME6_YPD Deaf3 Keogh05 0.3 0.4939 118RPN4_H2O2LoEAF7 Krogan04 0.3 0.4939 96REB1_YPD taf1-ts2_GCN5Huisinga04 0.3 0.494 131XBP1_H2O2Lo DT_V71E Chitikila_02 -0.3 0.4942 67ROX1_YPD set1 Boa03 0.3 0.4944 67AFT2_H2O2Lo sin3 Fazzio01 0.3 0.4946 95DAL82_RAPA WT_Null_L Chitikila_02 0.3 0.4948 53AFT2_H2O2Lo _SWC2_(VPS72)Krogan04 0.3 0.4952 89STE12_BUT90 arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.3 0.4953 68ACE2_YPD hpa2D Durant06 -0.3 0.4953 58YAP6_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 0.3 0.4955 46DIG1_BUT14 hht2_K4914182327GMartin04 -0.3 0.4956 56AFT2_H2O2Hi Dsin3 Keogh05 0.3 0.4959 54STE12_BUT14 SIN3 Hughes00 0.3 0.4968 128PHO4_YPD taf1-ts2_spt3 Huisinga04 -0.3 0.4972 69REB1_H2O2Hi spt10 Eriksson05 -0.3 0.4972 59ROX1_YPD MOT1-14 Dasgupta02 0.3 0.4976 67PHD1_YPD WT_F182V Chitikila_02 0.3 0.4977 55DAL82_SM Drco1 Keogh05 -0.3 0.4977 52DAL82_RAPA EPL1 Mnaimneh_04 0.3 0.4978 55XBP1_H2O2Lo Deaf3 Keogh05 0.3 0.4979 55CBF1_SM Deaf3 Keogh05 -0.3 0.4981 239REB1_H2O2Hi MOT1-42 Dasgupta02 -0.3 0.4981 58RPN4_H2O2LoUBP8 Hughes00 -0.3 0.4981 99DAL82_RAPA ino80_+_0.1%_MMS_vs._ino80Attikum04 0.3 0.4982 44CIN5_YPD PCH1 Hughes00 0.3 0.4983 149MBP1_H2O2Lospt3 Huisinga04 -0.3 0.4985 55MBP1_H2O2HiDT_V161R_K Chitikila_02 -0.3 0.499 127YAP6_YPD RSC8 Mnaimneh_04 -0.3 0.4991 91RIM101_H2O2LoSWD2 Mnaimneh_04 0.3 0.4992 54RPN4_H2O2LoWT_V71E Chitikila_02 0.3 0.4992 85SWI5_YPD isw2 Fazzio01 0.3 0.4994 94TYE7_YPD SIN3 Hughes00 -0.3 0.4999 56HSF1_H2O2Hi Drxt2 Keogh05 0.3 0.5 117TYE7_YPD TAF2 Mnaimneh_04 0.3 0.5001 54RCS1_H2O2Hi RSC8 Mnaimneh_04 0.3 0.5002 52

ACE2_YPD Ddep1 Keogh05 0.3 0.5002 77FKH2_YPD Hda1_del Bernstein02 -0.3 0.5003 121ABF1_YPD Drco1 Keogh05 0.3 0.5005 256REB1_YPD HIR2 Hughes00 0.3 0.5005 143STP1_SM hat1D_taf1-ts2Durant06 0.3 0.5005 57FKH1_YPD Dsds3 Keogh05 0.3 0.5006 135ROX1_YPD EAF5 Krogan04 0.3 0.5007 61REB1_H2O2Hi SPT8 Ingvarsdottir05 0.3 0.5007 54FKH2_YPD RSC8 Mnaimneh_04 0.3 0.5008 121YAP7_H2O2Lo WT_TAF1_SPT3Huisinga04 0.3 0.5009 148FKH2_YPD sas3D Durant06 -0.3 0.5009 102STE12_BUT14 hat1D Durant06 0.29 0.5012 98RLM1_YPD gcn5D Durant06 -0.29 0.5014 46CIN5_H2O2Lo sas3D Durant06 0.29 0.5014 97STP1_SM delta_ssd1 Kaeberlein04 -0.29 0.5018 66YAP1_YPD ume6 Fazzio01 -0.29 0.502 68YAP6_H2O2Lo WT_N69R Chitikila_02 0.29 0.5022 54DIG1_BUT14 DT_V71R Chitikila_02 -0.29 0.5023 61MBP1_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.29 0.5024 104MCM1_YPD H3_1-28 Sabet04 -0.29 0.5024 73NDD1_YPD WT Durant06 0.29 0.5024 78SWI6_YPD rsc30_null Angus-Hill_01 0.29 0.5025 151RIM101_H2O2Lotaf1-ts2_spt3_E240KHuisinga04 -0.29 0.5026 46CBF1_SM HST3 Hughes00 -0.29 0.5027 274HAP1_YPD SPT3 Ingvarsdottir05 -0.29 0.5027 121OAF1_YPD spt10 Eriksson05 0.29 0.503 58SWI5_YPD sas3D Durant06 0.29 0.5032 83TYE7_YPD swr1 Meneghini03 0.29 0.5033 41GCR2_SM HDA1 Hughes00 -0.29 0.5033 53XBP1_H2O2Lo WT_Null_L Chitikila_02 -0.29 0.5037 64TYE7_YPD MOT1-14 Dasgupta02 -0.29 0.5038 55ASH1_BUT14 gcn5_KQL Huisinga04 -0.29 0.5039 38RCS1_H2O2Hi sas3D Durant06 -0.29 0.504 40PUT3_H2O2Lo esa1-414_taf1-ts2Durant06 0.29 0.504 80SKN7_H2O2Hi ume6_del Bernstein_00_affydeletions-0.29 0.5043 89SOK2_BUT14 ISW2 Hughes00 -0.29 0.5045 72MBP1_H2O2Lohtz1_sir2 Meneghini03 0.29 0.5046 57ROX1_YPD SWD2 Mnaimneh_04 -0.29 0.505 67REB1_YPD esa1-414_taf1-ts2Durant06 -0.29 0.5052 130UME6_H2O2HiWT_V161R_K Chitikila_02 0.29 0.5052 87STE12_Alpha hpa2D Durant06 -0.29 0.5052 80RLM1_YPD ume6 Fazzio01 0.29 0.5054 54MGA1_YPD ISW2 Hughes00 0.29 0.5056 62CIN5_YPD DT_V71R Chitikila_02 0.29 0.5059 143SKN7_H2O2Hi rsc3-2 Angus-Hill_01 -0.29 0.5059 98MBP1_H2O2LoEAF5 Krogan04 -0.29 0.5059 49RCS1_H2O2Hi esa1-414_taf1-ts2Durant06 0.29 0.506 47SKN7_H2O2HiDsin3 Keogh05 0.29 0.506 72OAF1_YPD SGF11 Ingvarsdottir05 -0.29 0.506 44MCM1_YPD SGF11 Ingvarsdottir05 0.29 0.5063 62ACE2_YPD hos2_del Bernstein_00_affydeletions0.29 0.5065 75SWI5_YPD SPT3 Ingvarsdottir05 0.29 0.5066 87YAP1_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.29 0.5067 67

STE12_Alpha gcn5_KQL Huisinga04 -0.29 0.5069 98TYE7_YPD hat1D_taf1-ts2Durant06 0.29 0.5074 46MSN2_H2O2Hidelta_ssd1 Kaeberlein04 0.29 0.5076 78FKH2_YPD DT_V71R Chitikila_02 0.29 0.5076 116DAL82_SM ISW2 Hughes00 0.29 0.5077 55AFT2_H2O2Hi rpd3 Fazzio01 0.29 0.5077 58DAL81_RAPA YAF9 Krogan04 -0.29 0.508 87ACE2_YPD WT_V161R_L Chitikila_02 -0.29 0.5081 76STE12_YPD UBP8 Ingvarsdottir05 0.29 0.5083 52GCN4_RAPA hht2_K27G Martin04 -0.29 0.5083 131RIM101_H2O2LoSPT3 Ingvarsdottir05 -0.29 0.5085 50STE12_BUT90 WT_Null_K Chitikila_02 -0.29 0.5086 74STP1_SM Dume1 Keogh05 0.29 0.5087 61NRG1_H2O2HiEAF5 Krogan04 -0.29 0.5087 115RLM1_YPD Dume1 Keogh05 -0.29 0.509 51CIN5_H2O2Lo WT_WT Chitikila_02 0.29 0.509 122STE12_Alpha SIR3 Hughes00 -0.29 0.5093 113YAP1_YPD WT_WT Chitikila_02 -0.29 0.5094 69NRG1_YPD Deaf3 Keogh05 -0.29 0.5094 63UME6_H2O2HiWT_TAF1_SPT3Huisinga04 -0.29 0.5095 94FKH1_YPD UBP8 Hughes00 -0.29 0.5096 140RLM1_YPD ISW1 Hughes00 0.29 0.5097 55PHO4_YPD WT_V161R_K Chitikila_02 0.29 0.5099 66FKH1_YPD esa1-414_taf1-ts2Durant06 -0.29 0.51 125MCM1_YPD SWC6_(VPS71)Krogan04 0.29 0.51 72SWI5_YPD SPT8 Ingvarsdottir05 -0.29 0.5101 93FKH1_YPD DT_Null Chitikila_02 0.29 0.5102 133AFT2_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 0.29 0.5104 54ABF1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.29 0.5105 233MSN4_H2O2Hiswr1_del Mizuguch04 0.29 0.5106 70REB1_YPD DM_vs._YPH250Rosaleny05 0.29 0.5109 138RIM101_H2O2Lohat1_vs.YPH250Rosaleny05 0.29 0.5109 48STP1_SM SSD1-V Kaeberlein04 -0.29 0.5111 67HAP4_YPD snf2_minimal_medium_experimentSudarsanam00 -0.29 0.5112 67MSN4_RAPA htz1_sir2 Meneghini03 -0.29 0.5113 49DAL81_RAPA SSN6_haploid Hughes00 0.29 0.5114 93REB1_H2O2Hi DM_vs._YPH250Rosaleny05 -0.29 0.5114 53DIG1_BUT14 WT_Null_K Chitikila_02 0.29 0.5114 62PHO4_YPD ISW1 Hughes00 0.29 0.5115 70RCS1_H2O2Hi WT_V161E Chitikila_02 -0.29 0.5115 46SWI5_YPD Dsap30 Keogh05 0.29 0.5117 97YAP7_H2O2Hi DT_V161R_K Chitikila_02 0.29 0.5118 137NRG1_YPD SIR1 Hughes00 0.29 0.5118 72STP1_SM isw2_c.i._rpd3_c.i.Fazzio01 -0.29 0.5121 67SKN7_H2O2Hi swr1_del Mizuguch04 0.29 0.5121 97MCM1_Alpha UBP8 Ingvarsdottir05 0.29 0.5122 101YAP6_YPD arp8 Attikum04 0.29 0.5123 65MSN4_H2O2Hiisw2 Fazzio01 0.29 0.5123 68MBP1_YPD hht2_K27G Martin04 0.29 0.5123 112ASH1_BUT14 DT_WT Chitikila_02 0.29 0.5125 49RIM101_H2O2Lohpa2D Durant06 -0.29 0.5126 39RCS1_H2O2Hi WT_WT Chitikila_02 -0.28 0.5131 49RPN4_H2O2LoHda1_del Bernstein02 -0.28 0.5131 100

YAP6_YPD SWD2 Mnaimneh_04 0.28 0.5132 91MCM1_YPD ISW2 Hughes00 0.28 0.5134 77ROX1_YPD isw2_sin3 Fazzio01 -0.28 0.5136 67UME6_YPD SPT8 Ingvarsdottir05 -0.28 0.5137 119DAL82_SM hda1_del Bernstein_00_affydeletions0.28 0.5137 48DAL81_RAPA hda1_del Bernstein_00_affydeletions0.28 0.5138 92RTG3_RAPA Dume1 Keogh05 0.28 0.5139 48ASH1_BUT14 SWC6_(VPS71)Krogan04 0.28 0.5139 44YAP6_H2O2Hi hos3_del Bernstein_00_affydeletions-0.28 0.5142 68AFT2_H2O2Lo WT_N69S Chitikila_02 0.28 0.5144 89DIG1_Alpha snf2_rich_medium_experimentSudarsanam00 0.28 0.5144 59YAP1_YPD SWR1 Krogan04 -0.28 0.5145 67MCM1_Alpha DT_V161R_L Chitikila_02 0.28 0.5145 102AFT2_H2O2Hi ISW1_ISW2 Hughes00 -0.28 0.5146 61ROX1_YPD arp8 Attikum04 0.28 0.5153 47PUT3_H2O2Lo hat1_vs.YPH250Rosaleny05 0.28 0.5155 86UME6_YPD WT_TAF1_GCN5Huisinga04 0.28 0.5156 129UME6_H2O2Hihht2_K49141823GMartin04 0.28 0.5157 73STE12_BUT90 HST3 Hughes00 -0.28 0.5157 77REB1_YPD elp3D_taf1-ts2Durant06 -0.28 0.5158 115RCS1_H2O2LoDrxt1 Keogh05 0.28 0.5158 258STE12_BUT14 SIR2 Hughes00 -0.28 0.516 127RLM1_YPD Ddep1 Keogh05 0.28 0.5163 55MGA1_YPD hat1D_taf1-ts2Durant06 -0.28 0.5163 44RLM1_YPD snf2_rich_medium_experimentSudarsanam00 -0.28 0.5166 54TYE7_YPD ZDS1 Hughes00 0.28 0.5168 56MCM1_YPD IES6 Hughes00 -0.28 0.5168 77CBF1_SM hos3_del Bernstein_00_affydeletions0.28 0.5173 265YAP7_H2O2Hi DT_V161E Chitikila_02 -0.28 0.5176 136ROX1_YPD HTZ1 Krogan04 0.28 0.5178 62XBP1_H2O2Lo delta_ssd1 Kaeberlein04 -0.28 0.5178 68MSN2_H2O2HiWT_Null_K Chitikila_02 -0.28 0.5179 77RTG3_RAPA DT_V71R Chitikila_02 0.28 0.518 51MGA1_YPD SWD2 Mnaimneh_04 -0.28 0.5181 63SUT1_YPD SIR4 Hughes00 -0.28 0.5184 69STE12_Alpha ISW1 Hughes00 0.28 0.5184 115YAP6_YPD Dsap30 Keogh05 -0.28 0.5185 89MBP1_YPD elp3D Durant06 0.28 0.5185 110YAP6_H2O2Lo ZDS1 Hughes00 0.28 0.5186 56SWI5_YPD SIR2 Hughes00 0.28 0.5189 99SUM1_YPD hht2_K27G Martin04 -0.28 0.5194 25ROX1_YPD H3_1-28 Sabet04 0.28 0.52 58PHO4_YPD SAP30 Hughes00 0.28 0.5202 71GCR2_SM SIN3 Hughes00 0.28 0.5202 54MBP1_H2O2HiHTZ1 Krogan04 0.28 0.5202 121SWI6_YPD MOT1-14 Dasgupta02 -0.28 0.5207 152FKH2_H2O2Hi hda1_del Bernstein_00_affydeletions-0.28 0.5207 102ROX1_YPD Ddep1 Keogh05 -0.28 0.5213 66SUM1_YPD SWC6_(VPS71)Krogan04 0.28 0.5216 45STP1_SM snf2_minimal_medium_experimentSudarsanam00 0.28 0.5217 67YAP7_H2O2Lo swr1 Meneghini03 -0.28 0.5218 126RTG3_RAPA hpa2D Durant06 0.28 0.5224 42MCM1_Alpha HAT2 Hughes00 0.28 0.5228 106

RCS1_H2O2Hi isw2_sin3_vs._sin3Fazzio01 -0.28 0.5229 50ACE2_YPD ISW1_ISW2 Hughes00 -0.28 0.523 79YAP6_H2O2Hi gcn5_KQL Huisinga04 0.28 0.5231 69PUT3_H2O2Lo DT_N69S Chitikila_02 0.28 0.5231 80PHO4_YPD hht2_K49141823GMartin04 0.28 0.5232 61MSN4_RAPA rpd3 Fazzio01 -0.28 0.5232 53PHO4_YPD taf1-ts2_GCN5Huisinga04 -0.28 0.5234 68STE12_YPD taf1-ts2_25C Huisinga04 0.28 0.5234 48NRG1_YPD WT_Null_L Chitikila_02 0.28 0.5234 69RIM101_H2O2LoDT_Null Chitikila_02 0.28 0.5235 51GCN4_RAPA Deaf3 Keogh05 0.28 0.5236 138SUM1_YPD BUR6 Geisberg_01 -0.28 0.5237 50SWI6_YPD hat1D Durant06 0.28 0.5239 119RPN4_H2O2LoDT_V71E Chitikila_02 0.28 0.5243 95TYE7_YPD taf1-ts2_SPT3 Huisinga04 0.28 0.5245 52RCS1_H2O2Hi gcn5D_taf1-ts2Durant06 -0.28 0.5245 49PUT3_H2O2Lo WT_WT Chitikila_02 0.28 0.5245 82FKH1_YPD DM_vs._YPH250Rosaleny05 0.28 0.5245 129CBF1_SM MOT1-42 Dasgupta02 -0.28 0.5246 278SKN7_H2O2Logcn5 Huisinga04 0.28 0.5247 173FKH2_H2O2Hi hpa2D_taf1-ts2Durant06 -0.27 0.525 77RTG3_RAPA DT_V161R_K Chitikila_02 0.27 0.5251 51UME6_H2O2HiHTZ1 Krogan04 0.27 0.5251 88AFT2_H2O2Lo SIR4 Hughes00 0.27 0.5252 98REB1_H2O2Hi UBP8 Ingvarsdottir05 -0.27 0.5254 52SKN7_H2O2Hi isw2_ume6 Fazzio01 -0.27 0.5254 95GCN4_SM isw2_c.i. Fazzio01 -0.27 0.5257 183TYE7_YPD WT_V71E Chitikila_02 0.27 0.5258 49SWI4_YPD BUR6 Geisberg_01 -0.27 0.5261 143FKH2_H2O2Hi WT_TAF1_SPT3Huisinga04 -0.27 0.5262 103RIM101_H2O2LoYAF9 Krogan04 0.27 0.5262 51TYE7_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 0.27 0.5263 52MBP1_YPD isw2_sin3_vs._sin3Fazzio01 -0.27 0.5263 123DIG1_BUT14 H3KQ Sabet04 0.27 0.5265 63GCN4_YPD H4_2-26 Sabet04 0.27 0.5265 74PHD1_BUT90 DT_V71E Chitikila_02 0.27 0.5267 103AFT2_H2O2Lo sas3D_taf1-ts2Durant06 0.27 0.5268 90AFT2_H2O2Hi YAF9 Krogan04 -0.27 0.5272 59REB1_H2O2Hi taf1-ts2_spt3 Huisinga04 0.27 0.5273 58GCN4_YPD ino80_del Mizuguch04 -0.27 0.5273 74MSN4_RAPA rpd3_del Sabet04 0.27 0.5274 52STE12_YPD WT_V71R Chitikila_02 -0.27 0.5275 44SWI4_YPD hat1_vs.YPH250Rosaleny05 0.27 0.5275 150YAP7_H2O2Hi set1 Boa03 -0.27 0.5275 137RCS1_H2O2Loubp10 Orlandi04 0.27 0.5275 180XBP1_H2O2Lo HTZ1 Krogan04 0.27 0.5277 66YAP1_YPD ino80_del Mizuguch04 -0.27 0.5281 72SWI6_YPD hht2_K914182327GMartin04 0.27 0.5282 127DAL82_SM hat2_vs._hat1Rosaleny05 -0.27 0.5282 51YAP6_H2O2Lo elp3D Durant06 -0.27 0.5282 42HSF1_H2O2Lo isw2 Fazzio01 0.27 0.5285 97PHO4_YPD rpd3_del Sabet04 0.27 0.5288 70SWI5_YPD sin3 Fazzio01 -0.27 0.5289 94

CIN5_YPD swr1 Meneghini03 -0.27 0.529 123STP1_SM isw2_sin3 Fazzio01 0.27 0.529 67STP1_SM sas3D Durant06 -0.27 0.5292 55STE12_Alpha WT_V161R_K Chitikila_02 0.27 0.5292 102AFT2_H2O2Hi DT_N69R Chitikila_02 -0.27 0.5293 56RTG3_RAPA hht2_K49141823GMartin04 0.27 0.5294 42OAF1_YPD hat1D_taf1-ts2Durant06 0.27 0.5294 50MSN4_RAPA HST3 Hughes00 0.27 0.5295 54AFT2_H2O2Hi UBP8 Hughes00 0.27 0.5296 59UME6_H2O2HiDT_V161E Chitikila_02 0.27 0.5298 92YAP6_H2O2Hi hpa2D Durant06 -0.27 0.5298 57YAP7_H2O2Lo WT_Null_L Chitikila_02 -0.27 0.5299 139MCM1_Alpha hht2_K27G Martin04 0.27 0.5304 87MCM1_YPD sas3D_taf1-ts2Durant06 -0.27 0.5307 65PHD1_BUT90 hat1_vs.YPH250Rosaleny05 0.27 0.5309 97STE12_Alpha hos3_del Bernstein_00_affydeletions-0.27 0.5311 105FKH2_YPD hda1_del Bernstein_00_affydeletions0.27 0.5311 116REB1_YPD rsc30_null Angus-Hill_01 0.27 0.5312 140DIG1_Alpha hat2_vs._YPH250Rosaleny05 -0.27 0.5315 55REB1_YPD SWC6_(VPS71)Krogan04 -0.27 0.5317 131HSF1_H2O2Loswr1 Meneghini03 0.27 0.5317 86CBF1_SM ISW2 Hughes00 -0.27 0.5318 276GCN4_RAPA RSC8 Mnaimneh_04 0.27 0.5319 160XBP1_H2O2Lo SIR3 Hughes00 0.27 0.5319 67RCS1_H2O2LoDrxt2 Keogh05 0.27 0.5324 240AFT2_H2O2Hi isw2_sin3 Fazzio01 -0.27 0.5325 58PHO4_YPD gcn5_KQL Huisinga04 -0.27 0.5326 61ACE2_YPD Drxt2 Keogh05 0.27 0.5327 80DAL82_SM taf1-ts2 Durant06 0.27 0.5328 55CIN5_H2O2Lo DT_WT Chitikila_02 -0.27 0.5328 121AFT2_H2O2Hi set1 Boa03 0.27 0.5329 61HSF1_H2O2Hi swr1 Meneghini03 0.27 0.5329 110SKN7_H2O2HiDT_V71R Chitikila_02 0.27 0.5329 92DIG1_Alpha SIN3 Hughes00 0.27 0.5329 60DIG1_BUT14 DM_vs._YPH250Rosaleny05 0.27 0.5329 55DIG1_BUT14 TAF2 Mnaimneh_04 0.27 0.533 62FKH1_YPD SIR1 Hughes00 -0.27 0.5332 139CBF1_SM snf2_rich_medium_experimentSudarsanam00 0.27 0.5343 277HSF1_H2O2Hi hht2_K49141823GMartin04 0.27 0.5345 98SKN7_H2O2HiH3KQ Sabet04 0.27 0.5345 92MCM1_YPD rpd3_H3dN_v_H3dNSabet04 -0.27 0.5345 73DAL82_SM DT_WT Chitikila_02 -0.27 0.535 51XBP1_H2O2Lo taf1-ts2_25C Huisinga04 -0.27 0.535 63DAL82_SM YAF9 Krogan04 -0.27 0.5351 50MGA1_YPD taf1-ts2_GCN5Huisinga04 0.27 0.5351 54YAP1_YPD SAP30 Hughes00 0.27 0.5352 70RCS1_H2O2Hi rpd3 Fazzio01 -0.27 0.5352 50STE12_YPD rsc3-2 Angus-Hill_01 -0.27 0.5355 51SWI6_YPD spt10 Eriksson05 -0.27 0.5358 152MCM1_Alpha sir4 Orlandi04 -0.27 0.5358 71DIG1_Alpha WT_Null_K Chitikila_02 -0.27 0.5361 54PUT3_H2O2Lo gcn5D_taf1-ts2Durant06 0.27 0.5365 80RPN4_H2O2Loset1 Boa03 -0.27 0.5366 100

UME6_H2O2HiSet1_del Bernstein02 -0.27 0.5368 100OAF1_YPD SSD1-V Kaeberlein04 0.27 0.5368 59DIG1_Alpha HST3 Hughes00 -0.27 0.537 59HAP4_YPD delta_ssd1 Kaeberlein04 0.27 0.537 67SWI5_YPD spt3 Huisinga04 -0.26 0.5371 97MSN4_RAPA hmr Meneghini03 -0.26 0.5371 50REB1_YPD sin3_del Bernstein_00_affydeletions0.26 0.5374 137SUT1_YPD Drpd3 Keogh05 0.26 0.5374 61DAL82_RAPA hos2_del Bernstein_00_affydeletions-0.26 0.5374 50DAL81_RAPA rpd3 Fazzio01 -0.26 0.5376 91DAL82_SM DT_N69R Chitikila_02 0.26 0.538 53ACE2_YPD H3KQ Sabet04 0.26 0.5387 77ABF1_YPD SIR3 Hughes00 -0.26 0.5392 264SUM1_YPD ZDS1 Hughes00 0.26 0.5394 59SWI5_YPD hat1D Durant06 -0.26 0.5394 77DIG1_Alpha SGF11 Ingvarsdottir05 -0.26 0.5394 50HAP1_YPD RAD6_haploid Hughes00 0.26 0.5397 140MCM1_YPD sir2 Meneghini03 -0.26 0.5398 77RCS1_H2O2Hi Dsap30 Keogh05 0.26 0.54 51MSN4_H2O2Hidelta_ssd1 Kaeberlein04 0.26 0.5401 70SWI5_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.26 0.5406 78GCR2_SM Dsap30 Keogh05 0.26 0.5406 53FKH2_H2O2Hi SIR4 Hughes00 0.26 0.5406 106MBP1_H2O2Lodelta_ssd1 Kaeberlein04 0.26 0.5406 57MCM1_YPD gcn5D_taf1-ts2Durant06 0.26 0.5406 69YAP1_YPD taf1-ts2_25C Huisinga04 -0.26 0.5407 64REB1_H2O2Hi SAP30 Hughes00 0.26 0.5408 58MBP1_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.26 0.541 106MCM1_Alpha swr1 Meneghini03 -0.26 0.541 92AFT2_H2O2Lo taf1-ts2_SPT3 Huisinga04 0.26 0.5413 95UME6_YPD WT_Null_L Chitikila_02 0.26 0.5414 121GCR2_SM SWR1 Krogan04 0.26 0.5415 52SUM1_YPD Drco1 Keogh05 -0.26 0.5416 48DAL82_RAPA HST3 Hughes00 0.26 0.5417 56SKN7_H2O2LoISW2 Hughes00 0.26 0.5422 184DAL82_SM delta_ssd1 Kaeberlein04 0.26 0.5425 55MBP1_H2O2LoWT_V161E Chitikila_02 -0.26 0.5425 54DIG1_Alpha WT_V71R Chitikila_02 0.26 0.5425 51NDD1_YPD set1 Boa03 0.26 0.5426 82SUT1_YPD ubp10sir4 Orlandi04 -0.26 0.5429 42DAL81_RAPA hos3_del Bernstein_00_affydeletions0.26 0.5429 93STE12_Alpha SIR1 Hughes00 0.26 0.5431 115FKH2_YPD isw2 Fazzio01 0.26 0.5431 119MSN2_H2O2HiIOC4 Hughes00 -0.26 0.5432 76REB1_YPD Dsap30 Keogh05 -0.26 0.5433 138YAP1_YPD ubp10 Orlandi04 -0.26 0.5434 51PHD1_YPD WT_V161R_K Chitikila_02 -0.26 0.5435 59DAL82_SM rpd3_del Sabet04 0.26 0.5438 50STE12_BUT90 sin3 Fazzio01 0.26 0.5447 77SWI4_YPD rsc3-2 Angus-Hill_01 -0.26 0.5449 153FKH2_YPD taf1-ts2_GCN5Huisinga04 -0.26 0.5449 113TYE7_YPD DT_N69R Chitikila_02 -0.26 0.5452 51FKH2_H2O2Hi PCH1 Hughes00 0.26 0.5452 105

DAL81_RAPA rpd3_del Sabet04 -0.26 0.5454 94GCN4_SM isw2_c.i._rpd3_c.i.Fazzio01 0.26 0.5455 183ACE2_YPD DT_V161R_L Chitikila_02 -0.26 0.5456 74AFT2_H2O2Hi hat2_vs._YPH250Rosaleny05 0.26 0.5458 57SOK2_BUT14 HTZ1 Krogan04 -0.26 0.5458 67UME6_H2O2HiSIR2 Hughes00 -0.26 0.5461 100YAP6_H2O2Hi WT_Null_L Chitikila_02 -0.26 0.5461 72CIN5_H2O2Hi Deaf3 Keogh05 -0.26 0.5464 72MSN4_H2O2Hisin3_del Bernstein_00_affydeletions0.26 0.5464 63RPN4_H2O2LoARP4 Mnaimneh_04 0.26 0.5467 100YAP6_H2O2Lo H3_1-28 Sabet04 -0.26 0.5467 51MBP1_YPD spt10_del Xu05 -0.26 0.5468 126MGA1_YPD taf1-ts2_SPT3 Huisinga04 0.26 0.5468 57SWI4_YPD WT_TAF1_SPT3Huisinga04 0.26 0.5469 151GLN3_RAPA spt3_E240K Huisinga04 0.26 0.5471 61ACE2_YPD spt10 Eriksson05 -0.26 0.5472 80STE12_YPD hat2_vs._hat1Rosaleny05 0.26 0.5475 51PUT3_H2O2Lo taf1-ts2_SPT3 Huisinga04 0.26 0.5476 81MCM1_Alpha hpa2D_taf1-ts2Durant06 0.26 0.5476 70FKH2_YPD taf1-ts2 Durant06 0.26 0.5479 118YAP6_H2O2Lo sas3D Durant06 -0.26 0.548 43RPN4_H2O2Loisw2_ume6 Fazzio01 0.26 0.5483 97STP1_SM YNG2 Krogan04 -0.26 0.5485 64YAP7_H2O2Hi rpd3_H3dN_v_H3dNSabet04 0.26 0.5486 138SKN7_H2O2Hi ino80_+_0.1%_MMS_vs._ino80Attikum04 0.26 0.5487 73NRG1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.26 0.5488 38TYE7_YPD Set1_del Bernstein02 -0.26 0.549 54STE12_Alpha SIN3 Hughes00 0.26 0.549 115ABF1_YPD Dume1 Keogh05 0.26 0.5492 240YAP6_H2O2Hi EAF7 Krogan04 0.26 0.5492 70STE12_Alpha hda1_del Bernstein_00_affydeletions0.25 0.5496 104PHO4_YPD htz1_del Mizuguch04 -0.25 0.5497 71ROX1_YPD SAP30 Hughes00 0.25 0.5499 67UME6_YPD rsc3-2 Angus-Hill_01 0.25 0.5499 129PHO4_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 0.25 0.55 57SWI4_YPD rpd3_c.i. Fazzio01 0.25 0.5501 152NRG1_H2O2HiDT_N69R Chitikila_02 0.25 0.5502 115SKN7_YPD set1 Boa03 0.25 0.5504 64ROX1_YPD _SWC2_(VPS72)Krogan04 0.25 0.5505 65NRG1_H2O2HiZDS1 Hughes00 -0.25 0.5505 124SKN7_H2O2HiH3_1-28 Sabet04 0.25 0.5505 92FKH1_YPD MED2_haploid Hughes00 -0.25 0.5506 141RIM101_H2O2LoIOC4 Hughes00 0.25 0.5508 53MGA1_YPD taf1-ts2_gcn5 Huisinga04 0.25 0.5508 55MSN4_H2O2Hiswr1 Meneghini03 0.25 0.5509 58RCS1_H2O2LoSGF11 Ingvarsdottir05 -0.25 0.5509 223MBP1_H2O2HiSSN6_haploid Hughes00 -0.25 0.551 132MBP1_H2O2LoISW1_ISW2 Hughes00 -0.25 0.5514 58DIG1_Alpha WT_N69R Chitikila_02 -0.25 0.5517 50ABF1_YPD DM_vs._YPH250Rosaleny05 -0.25 0.5518 250RLM1_YPD DT_N69S Chitikila_02 -0.25 0.5519 47SWI5_YPD DM_vs._YPH250Rosaleny05 0.25 0.5519 91UME6_YPD ino80_del Mizuguch04 0.25 0.552 131

ABF1_YPD Ddep1 Keogh05 -0.25 0.5521 242PHO4_YPD WT_N69S Chitikila_02 0.25 0.5521 67ACE2_YPD hht2_K4G Martin04 -0.25 0.5522 64SKN7_YPD hat1D Durant06 -0.25 0.5523 49SWI5_YPD hht2K9131823GMartin04 0.25 0.5523 81FKH1_YPD DT_V71R Chitikila_02 -0.25 0.5523 136SKN7_YPD swi1_rich_medium_experimentSudarsanam00 -0.25 0.5524 67UME6_YPD SIR1 Hughes00 -0.25 0.5525 129MBP1_H2O2Loisw2 Fazzio01 0.25 0.5526 54OAF1_YPD swr1 Meneghini03 0.25 0.5527 45DAL82_SM rpd3_H3dN_v_H3dNSabet04 0.25 0.5529 50GCR2_SM DT_WT Chitikila_02 -0.25 0.5529 54AFT2_H2O2Hi isw2_rpd3 Fazzio01 0.25 0.553 58HAP1_YPD SWR1 Krogan04 0.25 0.5531 130STE12_BUT14 hat2_vs._hat1Rosaleny05 0.25 0.5532 121SWI5_YPD SSN6_haploid Hughes00 -0.25 0.5534 97CIN5_H2O2Lo htz1_del Mizuguch04 -0.25 0.5534 126MCM1_Alpha Dsin3 Keogh05 0.25 0.5534 88DIG1_Alpha TAF2 Mnaimneh_04 -0.25 0.5535 60STE12_BUT14 taf1-ts2_25C Huisinga04 0.25 0.5536 123MCM1_YPD SPT8 Ingvarsdottir05 -0.25 0.5536 70NDD1_YPD ume6_del Bernstein_00_affydeletions-0.25 0.5536 82FKH2_YPD hos2_del Bernstein_00_affydeletions0.25 0.5539 117GCN4_YPD swr1 Meneghini03 -0.25 0.5539 65YAP6_H2O2Hi DM_vs._YPH250Rosaleny05 0.25 0.554 64CIN5_H2O2Lo IOC4 Hughes00 -0.25 0.554 125YAP7_H2O2Hi YNG2 Krogan04 0.25 0.5541 137SUM1_YPD set1 Boa03 0.25 0.5542 58STP1_SM Dpho23 Keogh05 -0.25 0.5542 67STE12_BUT14 DT_N69R Chitikila_02 -0.25 0.5543 116RIM101_H2O2LoYNG2 Krogan04 0.25 0.5544 51MSN4_RAPA taf1-ts2_gcn5 Huisinga04 0.25 0.5547 51HSF1_H2O2Hi MED2_haploid Hughes00 0.25 0.5547 121SOK2_BUT14 HIR2 Hughes00 0.25 0.5547 70MGA1_YPD DT_N69S Chitikila_02 0.25 0.5548 56YAP7_H2O2Hi ARP4 Mnaimneh_04 0.25 0.5549 141YAP1_YPD Deaf3 Keogh05 0.25 0.555 64MSN4_H2O2HiYAF9 Krogan04 0.25 0.5551 65MSN4_H2O2HiDT_V71R Chitikila_02 -0.25 0.5552 70HAP4_YPD ubp10 Orlandi04 0.25 0.5553 44MGA1_YPD delta_ssd1 Kaeberlein04 0.25 0.5553 62RLM1_YPD WT_Null_K Chitikila_02 -0.25 0.556 51YAP6_YPD hat2_vs._hat1Rosaleny05 -0.25 0.5563 85NDD1_YPD DT_V71R Chitikila_02 -0.25 0.5564 82OAF1_YPD SWR1 Krogan04 -0.25 0.5564 53STE12_Alpha DT_V71E Chitikila_02 -0.25 0.5565 107RTG3_RAPA sap30_del Bernstein_00_affydeletions0.25 0.5566 48MBP1_YPD SPT3 Ingvarsdottir05 0.25 0.5566 119STE12_BUT14 TAF2 Mnaimneh_04 0.25 0.5567 127ROX1_YPD SIR4 Hughes00 -0.25 0.5574 67GCR2_SM ISW1_ISW2 Hughes00 0.25 0.5574 53DIG1_BUT14 swi1_minimal_medium_experimentSudarsanam00 -0.25 0.5574 63HSF1_H2O2LoSIR2 Hughes00 0.25 0.5575 100

PHD1_YPD WT_WT Chitikila_02 -0.25 0.558 63MSN2_H2O2Hihda1_del Bernstein_00_affydeletions0.25 0.5582 70SWI5_YPD hht2_K49141823GMartin04 0.25 0.5586 81AFT2_H2O2Lo taf1-ts2_spt3_E240KHuisinga04 0.25 0.5588 92RPN4_H2O2LoDpho23 Keogh05 -0.25 0.5588 100STE12_YPD hda1_del Bernstein_00_affydeletions0.25 0.5589 49TYE7_YPD isw2_c.i._rpd3_c.i.Fazzio01 -0.25 0.559 54OAF1_YPD isw2_sin3_vs._sin3Fazzio01 -0.25 0.559 56AFT2_H2O2Hi WT_V71E Chitikila_02 -0.25 0.5592 54UME6_YPD DT_N69S Chitikila_02 0.25 0.5593 111GCN4_RAPA rpd3_H4KQ_v_H4KQSabet04 0.25 0.5593 157MCM1_Alpha TAF2 Mnaimneh_04 0.25 0.5595 106MBP1_H2O2HiDT_N69R Chitikila_02 -0.25 0.5599 120YAP7_H2O2Hi hmr Meneghini03 -0.25 0.5599 134CIN5_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 0.25 0.56 69MSN4_H2O2HiWT Durant06 -0.25 0.5601 66PHO4_YPD swr1_del Mizuguch04 -0.25 0.5602 71DAL82_SM DT_V71R Chitikila_02 0.25 0.5604 52REB1_H2O2Hi HST3 Hughes00 -0.25 0.5604 57REB1_H2O2Hi sas3D Durant06 -0.25 0.5605 47SWI5_YPD DT_N69R Chitikila_02 0.25 0.561 89ASH1_BUT14 hos3_del Bernstein_00_affydeletions0.25 0.5612 43GLN3_RAPA WT_TAF1_SPT3Huisinga04 -0.25 0.5615 65TYE7_YPD rpd3_H3dN_v_H3dNSabet04 0.25 0.5616 54REB1_YPD ubp10sir4 Orlandi04 0.25 0.5617 107NRG1_YPD WT_TAF1_SPT3Huisinga04 -0.25 0.5618 68PHO4_YPD SWD2 Mnaimneh_04 0.25 0.5619 72SKN7_YPD hat2_vs._hat1Rosaleny05 0.25 0.562 61MBP1_H2O2HiDume1 Keogh05 0.25 0.5622 120ABF1_YPD isw2_sin3_vs._sin3Fazzio01 0.24 0.5624 263DAL82_RAPA set1 Boa03 0.24 0.5626 55STE12_BUT14 gcn5_KQL Huisinga04 -0.24 0.5626 108STE12_BUT14 Dsin3 Keogh05 -0.24 0.5629 110YAP6_YPD spt10_del Xu05 -0.24 0.563 89ACE2_YPD htz1_hmr Meneghini03 0.24 0.5632 79DAL81_RAPA Dume1 Keogh05 -0.24 0.5633 83MSN4_H2O2Hirpd3 Fazzio01 0.24 0.5634 68OAF1_YPD H3_1-28 Sabet04 0.24 0.5635 55STE12_YPD WT_N69R Chitikila_02 -0.24 0.5636 45FKH2_H2O2Hi arp8 Attikum04 0.24 0.5636 82YAP6_H2O2Hi WT_TAF1_SPT3Huisinga04 0.24 0.5638 72AFT2_H2O2Hi EAF7 Krogan04 -0.24 0.5639 54REB1_H2O2Hi taf1-ts2_gcn5 Huisinga04 -0.24 0.5639 55GCN4_RAPA hda1_del Bernstein_00_affydeletions0.24 0.5644 156SKN7_H2O2Hi hat1D Durant06 -0.24 0.5644 69UME6_H2O2Hihda1_del Bernstein_00_affydeletions0.24 0.5645 98MCM1_Alpha spt3_E240K Huisinga04 0.24 0.5645 95MBP1_H2O2Lorsc30_null Angus-Hill_01 0.24 0.5648 56MCM1_YPD UBP8 Ingvarsdottir05 0.24 0.5648 73TYE7_YPD Dsds3 Keogh05 -0.24 0.5649 52MSN4_H2O2HiPCH1 Hughes00 0.24 0.5649 69TYE7_YPD WT_N69R Chitikila_02 0.24 0.5654 51CIN5_H2O2Hi delta_ssd1 Kaeberlein04 -0.24 0.5659 80

PUT3_H2O2Lo isw2_ume6 Fazzio01 0.24 0.5661 86FKH1_YPD SWD2 Mnaimneh_04 0.24 0.5661 142MSN4_RAPA gcn5D Durant06 0.24 0.5662 38RLM1_YPD IOC4 Hughes00 -0.24 0.5666 54CBF1_SM arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.24 0.5667 233CIN5_H2O2Hi gcn5_KQL Huisinga04 -0.24 0.5667 73MBP1_YPD rpd3_H4KQ_v_H4KQSabet04 0.24 0.5668 126HSF1_H2O2Lorpd3 Fazzio01 0.24 0.5671 97DIG1_Alpha WT_V161R_K Chitikila_02 0.24 0.5672 51SKN7_H2O2Hi snf2_rich_medium_experimentSudarsanam00 -0.24 0.5674 97SUM1_YPD DT_V71R Chitikila_02 0.24 0.5675 53GCN4_SM sin3_del Bernstein_00_affydeletions0.24 0.5676 182DIG1_Alpha hht2_K914182327GMartin04 0.24 0.5681 43DIG1_BUT14 ume6 Fazzio01 -0.24 0.5681 63PHD1_BUT90 EAF7 Krogan04 0.24 0.5681 97DAL81_RAPA hat2_vs._YPH250Rosaleny05 0.24 0.5683 91FKH2_YPD RAD6_haploid Hughes00 0.24 0.5683 120YAP7_H2O2Lo WT Durant06 -0.24 0.5684 142HSF1_H2O2Hi ino80_del Mizuguch04 -0.24 0.5686 122YAP6_H2O2Lo taf1-ts2_gcn5_KQLHuisinga04 0.24 0.5686 51ABF1_YPD YNG2 Krogan04 -0.24 0.5689 256RPN4_H2O2LoHAT2 Hughes00 -0.24 0.5689 96GCN4_YPD SWC6_(VPS71)Krogan04 -0.24 0.569 67YAP7_H2O2Hi WT_TAF1_GCN5Huisinga04 -0.24 0.5691 141STE12_BUT90 htz1_sir2 Meneghini03 0.24 0.5696 76MBP1_YPD hat1_vs.YPH250Rosaleny05 0.24 0.5697 123GCN4_RAPA htz1 Meneghini03 0.24 0.5698 157GLN3_RAPA hht2_K4G Martin04 0.24 0.5699 51MBP1_H2O2Hi rsc3-2 Angus-Hill_01 -0.24 0.5702 129REB1_H2O2Hi hat2_vs._hat1Rosaleny05 -0.24 0.5705 55SKN7_H2O2Hi hos3_del Bernstein_00_affydeletions0.24 0.5706 84PUT3_H2O2Lo rpd3 Fazzio01 -0.24 0.5706 86SUT1_YPD WT_WT Chitikila_02 -0.24 0.5707 64SWI5_YPD SIR3 Hughes00 0.24 0.571 100RTG3_RAPA isw2 Fazzio01 -0.24 0.571 51ACE2_YPD Dume1 Keogh05 -0.24 0.5711 78CIN5_YPD hat1_vs.YPH250Rosaleny05 -0.24 0.5712 142STE12_BUT90 isw2_rpd3_vs._rpd3Fazzio01 -0.24 0.5713 77REB1_YPD H3KQ Sabet04 0.24 0.5714 141YAP6_H2O2Hi Dsin3 Keogh05 -0.24 0.5714 69SUM1_YPD esa1-414 Durant06 0.24 0.5715 47SKN7_H2O2LoHTZ1 Krogan04 0.24 0.5716 165RTG3_RAPA hht2_K4G Martin04 -0.24 0.5717 42MSN4_H2O2HiZDS1 Hughes00 0.24 0.5717 68ABF1_YPD hpa2D Durant06 0.24 0.5718 209REB1_H2O2Hi MOT1-14 Dasgupta02 -0.24 0.5718 58HAP1_YPD WT_TAF1_GCN5Huisinga04 -0.24 0.5718 141MSN4_H2O2HiDrxt2 Keogh05 0.24 0.572 67MCM1_YPD taf1-ts2_spt3 Huisinga04 -0.24 0.5721 71STE12_Alpha DT_V161R_K Chitikila_02 0.24 0.5722 108SWI4_YPD hat2_vs._YPH250Rosaleny05 0.24 0.5725 149PUT3_H2O2Lo EAF7 Krogan04 0.24 0.5727 76AFT2_H2O2Lo arp8 Attikum04 0.24 0.5729 67

DIG1_Alpha ino80_+_0.1%_MMS_vs._ino80Attikum04 0.24 0.573 42RPN4_H2O2LoWT_TAF1_GCN5Huisinga04 -0.24 0.5734 99DIG1_BUT14 ISW1 Hughes00 0.24 0.5734 63MBP1_YPD RSC8 Mnaimneh_04 -0.24 0.5734 130UME6_YPD IOC4 Hughes00 0.24 0.5737 128GLN3_RAPA YNG2 Krogan04 -0.24 0.5742 65PHO4_YPD hat1D Durant06 0.24 0.5743 55REB1_YPD rpd3_del Sabet04 0.24 0.5743 141FKH1_YPD DT_N69S Chitikila_02 -0.24 0.5743 132FKH2_YPD gcn5D_taf1-ts2Durant06 0.24 0.5744 114DAL82_SM swr1 Meneghini03 -0.24 0.5746 44FKH2_H2O2Hi isw2_sin3_vs._sin3Fazzio01 -0.24 0.5746 104SOK2_BUT14 SWC6_(VPS71)Krogan04 0.24 0.5746 66CIN5_H2O2Hi hpa2D_taf1-ts2Durant06 0.24 0.5747 53MBP1_H2O2Lohtz1_del Mizuguch04 0.24 0.5749 58RLM1_YPD HDA1 Hughes00 -0.24 0.575 54MGA1_YPD htz1_hmr Meneghini03 -0.24 0.575 59DIG1_BUT14 hat1_vs.YPH250Rosaleny05 -0.24 0.5753 60OAF1_YPD IOC4 Hughes00 0.24 0.5753 58CBF1_SM sas3D Durant06 0.23 0.5756 227RCS1_H2O2Hi hht2K9131823GMartin04 -0.23 0.5757 39STE12_YPD SIR1 Hughes00 0.23 0.5759 54MSN2_H2O2Hiino80 Attikum04 0.23 0.5759 63CIN5_YPD Dsds3 Keogh05 -0.23 0.576 137DAL82_RAPA gcn5 Huisinga04 -0.23 0.5761 54GCN4_YPD htz1 Meneghini03 0.23 0.5764 72TYE7_YPD MOT1-42 Dasgupta02 -0.23 0.5765 55ACE2_YPD sin3 Fazzio01 0.23 0.5768 74MGA1_YPD ISW1 Hughes00 -0.23 0.5771 62NDD1_YPD H3_1-28 Sabet04 -0.23 0.5772 83UME6_YPD snf2_rich_medium_experimentSudarsanam00 0.23 0.5774 130PHO4_YPD TAF2 Mnaimneh_04 0.23 0.5775 72MGA1_YPD SAP30 Hughes00 -0.23 0.5775 62AFT2_H2O2Hi SIR4 Hughes00 -0.23 0.5778 61DAL82_RAPA sir4 Orlandi04 0.23 0.5779 37PHD1_YPD hat1_vs.YPH250Rosaleny05 0.23 0.578 61DIG1_BUT14 IES6 Hughes00 -0.23 0.578 63SOK2_BUT14 rsc30_null Angus-Hill_01 -0.23 0.578 70SWI4_YPD hat2_vs._hat1Rosaleny05 0.23 0.5783 148XBP1_H2O2Lo WT_V161E Chitikila_02 0.23 0.5783 62HAP4_YPD SWD2 Mnaimneh_04 -0.23 0.5785 67OAF1_YPD WT Durant06 -0.23 0.5785 57CIN5_YPD Dsin3 Keogh05 -0.23 0.5787 126DAL82_RAPA ubp10sir4 Orlandi04 -0.23 0.5788 37CIN5_H2O2Hi SGF11 Ingvarsdottir05 0.23 0.5788 66TYE7_YPD esa1-414_taf1-ts2Durant06 -0.23 0.5789 51NDD1_YPD hos3_del Bernstein_00_affydeletions0.23 0.5789 82STE12_YPD hpa2D_taf1-ts2Durant06 0.23 0.5791 36AFT2_H2O2Lo MED2_haploid Hughes00 0.23 0.5791 98STE12_BUT14 rsc30_null Angus-Hill_01 -0.23 0.5791 122RCS1_H2O2Loesa1-414_taf1-ts2Durant06 -0.23 0.5793 235STE12_Alpha isw2_rpd3_vs._rpd3Fazzio01 0.23 0.5796 112XBP1_H2O2Lo HAT2 Hughes00 -0.23 0.5797 66

RIM101_H2O2LoEAF7 Krogan04 -0.23 0.5798 51OAF1_YPD HIR2 Hughes00 0.23 0.5801 58REB1_H2O2Hi hht2_K4G Martin04 0.23 0.5807 49MSN4_RAPA WT_N69R Chitikila_02 0.23 0.5811 49RCS1_H2O2Lorsc30_null Angus-Hill_01 0.23 0.5811 249PHO4_YPD hht2_K914182327GMartin04 0.23 0.5813 61PUT3_H2O2Lo esa1-414 Durant06 0.23 0.5813 81MSN4_RAPA DT_V161E Chitikila_02 0.23 0.5814 49NRG1_H2O2Hiarp8 Attikum04 0.23 0.5816 85DIG1_Alpha Set1_del Bernstein02 -0.23 0.5816 58MBP1_H2O2HiTAF2 Mnaimneh_04 0.23 0.5818 133MCM1_YPD sir4 Orlandi04 -0.23 0.5818 50DAL81_RAPA DT_V161R_K Chitikila_02 -0.23 0.5819 94DAL82_SM Dsin3 Keogh05 0.23 0.5823 46MSN2_H2O2HiSWC6_(VPS71)Krogan04 0.23 0.5823 70STE12_BUT14 HST3 Hughes00 -0.23 0.5823 128SOK2_BUT14 SWR1 Krogan04 -0.23 0.5824 71NRG1_H2O2HiRSC8 Mnaimneh_04 0.23 0.5825 126SOK2_BUT14 SSD1-V Kaeberlein04 -0.23 0.5825 72NDD1_YPD isw2_c.i. Fazzio01 0.23 0.5831 80FKH1_YPD UBP8 Ingvarsdottir05 -0.23 0.5837 132AFT2_H2O2Hi esa1-414_taf1-ts2Durant06 -0.23 0.5839 58RCS1_H2O2LoDpho23 Keogh05 0.23 0.5839 258SWI5_YPD rpd3_del Sabet04 0.23 0.5841 93DAL82_SM hht2_K914182327GMartin04 0.23 0.5842 40YAP6_H2O2Hi WT_V71E Chitikila_02 -0.23 0.5842 64YAP7_H2O2Hi snf2_minimal_medium_experimentSudarsanam00 0.23 0.5846 141GCR2_SM WT_Null_L Chitikila_02 0.23 0.5847 53YAP6_H2O2Hi YAF9 Krogan04 0.23 0.5847 77STE12_BUT14 spt10_del Xu05 0.23 0.5847 126MSN4_RAPA isw2_sin3 Fazzio01 -0.23 0.5848 53CIN5_YPD DT_V161R_K Chitikila_02 0.23 0.585 146GCR2_SM ISW2 Hughes00 0.23 0.585 54DIG1_Alpha H4_2-26 Sabet04 -0.23 0.5851 56GCN4_RAPA WT_TAF1_SPT3Huisinga04 0.23 0.5855 154FKH2_YPD hat2_vs._hat1Rosaleny05 -0.23 0.5859 116OAF1_YPD sap30_del Bernstein_00_affydeletions-0.23 0.586 52STE12_YPD DT_Null Chitikila_02 -0.23 0.5862 45CIN5_YPD Dsap30 Keogh05 -0.23 0.5863 141HAP1_YPD rsc3-2 Angus-Hill_01 0.23 0.5863 139YAP1_YPD DT_V161R_L Chitikila_02 0.23 0.5868 70PUT3_H2O2Lo rpd3_H4KQ_v_H4KQSabet04 0.23 0.5868 85MBP1_H2O2Hi swi1_rich_medium_experimentSudarsanam00 -0.23 0.587 133CIN5_H2O2Hi TAF2 Mnaimneh_04 0.23 0.5873 80YAP7_H2O2Hi Drxt1 Keogh05 0.23 0.5879 141DIG1_BUT14 taf1-ts2_gcn5 Huisinga04 0.23 0.5879 60RCS1_H2O2LoWT_Null_L Chitikila_02 -0.23 0.5881 236RLM1_YPD sin3_del Bernstein_00_affydeletions-0.23 0.5882 47UME6_YPD UBP8 Hughes00 0.23 0.5883 128AFT2_H2O2Hi hht2_K4G Martin04 -0.23 0.5883 44STE12_YPD TAF2 Mnaimneh_04 0.23 0.5885 54GCN4_YPD DT_N69R Chitikila_02 0.22 0.5889 70GCN4_SM TAF2 Mnaimneh_04 0.22 0.5891 189

UME6_YPD WT Durant06 0.22 0.5892 126DAL82_SM UBP8 Ingvarsdottir05 -0.22 0.5892 43REB1_H2O2Hi SIR1 Hughes00 -0.22 0.5892 58HSF1_H2O2LoDM_vs._YPH250Rosaleny05 0.22 0.5892 96TYE7_YPD SIR3 Hughes00 0.22 0.5893 56REB1_YPD Hda1_del Bernstein02 0.22 0.5896 140REB1_YPD DT_V161R_L Chitikila_02 -0.22 0.5896 133YAP7_H2O2Hi gcn5D Durant06 0.22 0.5896 123MSN4_H2O2HiSet1_del Bernstein02 0.22 0.5903 69ACE2_YPD isw2_sin3 Fazzio01 -0.22 0.5903 74MBP1_H2O2Loubp10 Orlandi04 0.22 0.5905 32TYE7_YPD WT_V161R_L Chitikila_02 -0.22 0.5906 50DAL82_SM H3_1-28 Sabet04 -0.22 0.5906 50MBP1_H2O2LoHTZ1 Krogan04 0.22 0.5909 52MBP1_H2O2HiRAD6_haploid Hughes00 -0.22 0.5912 131AFT2_H2O2Hi elp3D_taf1-ts2Durant06 0.22 0.5913 53YAP7_H2O2Hi elp3D Durant06 -0.22 0.5914 124PHO4_YPD SIR1 Hughes00 0.22 0.5915 70MSN4_RAPA YNG2 Krogan04 -0.22 0.5915 48MSN4_RAPA isw2_ume6 Fazzio01 -0.22 0.5917 53MCM1_Alpha hat2_vs._hat1Rosaleny05 -0.22 0.5919 99AFT2_H2O2Lo sir4 Orlandi04 -0.22 0.592 58RCS1_H2O2LoWT_F182V Chitikila_02 0.22 0.5921 216XBP1_H2O2Lo hos3_del Bernstein_00_affydeletions-0.22 0.5921 53NRG1_YPD HIR2 Hughes00 0.22 0.5921 72DAL82_RAPA hos3_del Bernstein_00_affydeletions-0.22 0.5922 52RIM101_H2O2Lohmr Meneghini03 0.22 0.5923 53PUT3_H2O2Lo DT_Null Chitikila_02 0.22 0.5926 86PUT3_H2O2Lo ARP4 Mnaimneh_04 0.22 0.5927 88ASH1_BUT14 taf1-ts2_spt3_E240KHuisinga04 -0.22 0.5927 45PUT3_H2O2Lo DT_V161E Chitikila_02 0.22 0.5928 83RIM101_H2O2LoEAF5 Krogan04 0.22 0.5929 49ACE2_YPD hda1_del Bernstein_00_affydeletions0.22 0.593 73TYE7_YPD BUR6 Geisberg_01 0.22 0.5933 54DAL82_SM gcn5D_taf1-ts2Durant06 0.22 0.5939 49YAP7_H2O2Lo VID21 Krogan04 0.22 0.5941 141MCM1_YPD Hda1_del Bernstein02 -0.22 0.5941 76RCS1_H2O2Lorpd3_H4KQ_v_H4KQSabet04 0.22 0.5948 253CIN5_H2O2Hi Dpho23 Keogh05 0.22 0.5949 79YAP6_YPD WT_V71E Chitikila_02 0.22 0.595 77HSF1_H2O2Hi SIR2 Hughes00 -0.22 0.595 123STE12_BUT90 isw2_rpd3 Fazzio01 0.22 0.5951 77PHD1_BUT90 ino80 Attikum04 0.22 0.5953 76YAP6_H2O2Lo HIR2 Hughes00 0.22 0.5954 58XBP1_H2O2Lo WT_WT Chitikila_02 0.22 0.5957 65FKH2_YPD SIR3 Hughes00 -0.22 0.5957 119UME6_H2O2Hi0.1%_MMS Attikum04 0.22 0.5964 74YAP7_H2O2Lo hda1_del Bernstein_00_affydeletions0.22 0.5964 143CIN5_YPD ZDS1 Hughes00 -0.22 0.5967 149DAL82_SM DM_vs._YPH250Rosaleny05 0.22 0.5967 52REB1_H2O2Hi SWD2 Mnaimneh_04 0.22 0.5967 59HSF1_H2O2Losin3 Fazzio01 -0.22 0.5968 97GLN3_RAPA taf1-ts2_spt3 Huisinga04 0.22 0.5979 61

UME6_H2O2Hihat2_vs._hat1Rosaleny05 0.22 0.5979 94AFT2_H2O2Lo ZDS1 Hughes00 0.22 0.5979 97FKH1_YPD elp3D Durant06 0.22 0.5979 112STE12_BUT90 H4KQ Sabet04 0.22 0.5979 74NDD1_YPD rpd3_H3dN_v_H3dNSabet04 -0.22 0.5979 83YAP6_H2O2Lo DT_V161R_K Chitikila_02 0.22 0.598 55STE12_BUT90 H3KQ Sabet04 0.22 0.5981 74REB1_YPD SIR3 Hughes00 -0.22 0.5984 142HSF1_H2O2Hi hht2_K27G Martin04 -0.22 0.5984 98HSF1_H2O2Lorpd3_H4KQ_v_H4KQSabet04 -0.22 0.5985 98UME6_H2O2Hitaf1-ts2_SPT3 Huisinga04 0.22 0.5986 93MBP1_H2O2LoDrco1 Keogh05 0.22 0.5986 54REB1_YPD Deaf3 Keogh05 0.22 0.5988 129PHO4_YPD hht2_K4914182327GMartin04 -0.22 0.5989 62RCS1_H2O2Hi WT_N69S Chitikila_02 -0.22 0.5993 44SKN7_H2O2Hi hht2K9131823GMartin04 0.22 0.5993 77PHD1_YPD hht2_K27G Martin04 -0.22 0.5996 45TYE7_YPD hat2_vs._YPH250Rosaleny05 -0.22 0.5999 52AFT2_H2O2Hi Drxt2 Keogh05 0.22 0.5999 57DIG1_BUT14 hda1_del Bernstein_00_affydeletions-0.22 0.6 61OAF1_YPD RPD3_haploid Hughes00 -0.22 0.6 59PHO4_YPD delta_ssd1 Kaeberlein04 0.22 0.6003 71MSN4_RAPA WT_F182V Chitikila_02 -0.22 0.6003 41ROX1_YPD hpa2D Durant06 -0.22 0.6004 48AFT2_H2O2Lo rsc30_null Angus-Hill_01 -0.22 0.6004 96GCR2_SM taf1-ts2_gcn5_KQLHuisinga04 0.22 0.6007 43SWI4_YPD IOC4 Hughes00 -0.22 0.6008 155STP1_SM rpd3_del Sabet04 -0.22 0.6008 67MSN4_H2O2Hiino80 Attikum04 -0.22 0.6008 59MCM1_Alpha EAF5 Krogan04 0.22 0.601 97STE12_BUT14 H3KQ Sabet04 -0.22 0.6013 122MBP1_H2O2Loset1 Boa03 -0.22 0.6018 57STP1_SM Dsds3 Keogh05 -0.22 0.6024 60RCS1_H2O2Lohtz1 Meneghini03 -0.22 0.6024 245AFT2_H2O2Lo hht2_K4914182327GMartin04 0.21 0.6026 69FKH2_YPD UBP8 Hughes00 -0.21 0.603 119MCM1_YPD rpd3_c.i. Fazzio01 0.21 0.603 73DIG1_Alpha hos2_del Bernstein_00_affydeletions-0.21 0.6032 54ASH1_BUT14 DT_V71R Chitikila_02 -0.21 0.6033 49MCM1_YPD WT Durant06 0.21 0.6033 75DIG1_Alpha EAF5 Krogan04 0.21 0.6036 57STE12_BUT90 EAF5 Krogan04 0.21 0.6038 72PHO4_YPD spt3 Huisinga04 -0.21 0.6039 71RLM1_YPD PCH1 Hughes00 0.21 0.6039 53SOK2_BUT14 EAF7 Krogan04 -0.21 0.6041 67AFT2_H2O2Lo spt3 Huisinga04 -0.21 0.6048 97MCM1_Alpha taf1-ts2_gcn5_KQLHuisinga04 0.21 0.6048 90RTG3_RAPA EPL1 Mnaimneh_04 0.21 0.6049 52DAL82_SM RAD6_haploid Hughes00 0.21 0.6051 54DIG1_BUT14 DT_V71E Chitikila_02 -0.21 0.6052 60RCS1_H2O2Loume6_del Bernstein_00_affydeletions0.21 0.6053 247STE12_Alpha HIR2 Hughes00 -0.21 0.6054 112DAL82_SM HAT2 Hughes00 0.21 0.6056 54

AFT2_H2O2Hi hht2_K49141823GMartin04 0.21 0.6056 44GCN4_RAPA MOT1-14 Dasgupta02 0.21 0.6059 157UME6_YPD WT_WT Chitikila_02 0.21 0.6061 118YAP7_H2O2Lo YNG2 Krogan04 0.21 0.6064 146GCN4_RAPA hos3_del Bernstein_00_affydeletions-0.21 0.6066 154DIG1_BUT14 DT_V161E Chitikila_02 -0.21 0.6066 55SWI6_YPD DT_Null Chitikila_02 -0.21 0.6067 148STP1_SM elp3D Durant06 0.21 0.6068 50STE12_Alpha IOC4 Hughes00 -0.21 0.6069 114PUT3_H2O2Lo hat1D_taf1-ts2Durant06 -0.21 0.6074 75HAP1_YPD HST3 Hughes00 0.21 0.6075 139AFT2_H2O2Hi isw2_c.i._rpd3_c.i.Fazzio01 -0.21 0.608 58SKN7_YPD rsc3-2 Angus-Hill_01 -0.21 0.6082 67DAL82_RAPA UBP8 Hughes00 0.21 0.6082 55XBP1_H2O2Lo hpa2D_taf1-ts2Durant06 0.21 0.6083 47DIG1_BUT14 DT_V161R_L Chitikila_02 -0.21 0.6083 58CIN5_H2O2Hi ubp10 Orlandi04 0.21 0.6085 43AFT2_H2O2Hi taf1-ts2_spt3 Huisinga04 -0.21 0.6088 60PHD1_YPD hmr Meneghini03 -0.21 0.609 66SKN7_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 0.21 0.609 44UME6_H2O2Hihht2_K914182327GMartin04 0.21 0.609 72MCM1_Alpha WT_Null_L Chitikila_02 0.21 0.6091 104MGA1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 0.21 0.6092 49MSN4_RAPA SWD2 Mnaimneh_04 -0.21 0.6094 53TYE7_YPD hpa2D Durant06 0.21 0.6095 43SWI5_YPD WT Durant06 -0.21 0.61 93CIN5_H2O2Lo WT_Null_L Chitikila_02 -0.21 0.6101 120PUT3_H2O2Lo SWR1 Krogan04 -0.21 0.6102 79SWI4_YPD WT_Null_K Chitikila_02 0.21 0.6104 149ACE2_YPD ino80_del Mizuguch04 0.21 0.6108 80SWI5_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.21 0.6112 94MBP1_H2O2Lotaf1-ts2_SPT3 Huisinga04 -0.21 0.6113 52DAL82_RAPA MED2_haploid Hughes00 0.21 0.6114 56YAP6_H2O2Lo YAF9 Krogan04 -0.21 0.6116 57SUM1_YPD taf1-ts2_spt3 Huisinga04 -0.21 0.6118 47AFT2_H2O2Lo WT_V71E Chitikila_02 0.21 0.6118 85SWI6_YPD snf2_rich_medium_experimentSudarsanam00 -0.21 0.6119 152STP1_SM RAD6_haploid Hughes00 -0.21 0.6119 66AFT2_H2O2Hi Drpd3 Keogh05 0.21 0.612 55ACE2_YPD sas3D Durant06 0.21 0.6121 67PHD1_YPD YAF9 Krogan04 -0.21 0.6123 64UME6_YPD hht2_K4G Martin04 -0.21 0.6123 92RCS1_H2O2LoSIR1 Hughes00 -0.21 0.6123 258YAP7_H2O2Hi MED2_haploid Hughes00 -0.21 0.6124 139SUM1_YPD delta_ssd1 Kaeberlein04 -0.21 0.6126 58MSN2_H2O2HiYAF9 Krogan04 0.21 0.6128 73SOK2_BUT14 Drpd3 Keogh05 -0.21 0.6128 66REB1_YPD DT_V71R Chitikila_02 -0.21 0.6131 131GCR2_SM Set1_del Bernstein02 -0.21 0.6132 54DAL82_RAPA PCH1 Hughes00 0.21 0.6132 55SUM1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 0.21 0.6133 30MGA1_YPD VID21 Krogan04 0.21 0.6134 60SWI4_YPD hat1D Durant06 0.21 0.6135 116

RCS1_H2O2Loino80 Attikum04 -0.21 0.6135 204PHO4_YPD DT_N69S Chitikila_02 0.21 0.6136 67YAP7_H2O2Hi gcn5_KQL Huisinga04 -0.21 0.614 127CBF1_SM 0.1%_MMS Attikum04 -0.21 0.6141 236CIN5_H2O2Lo ino80 Attikum04 -0.21 0.6143 91HSF1_H2O2Lohht2_K914182327GMartin04 0.21 0.6146 83PUT3_H2O2Lo Drpd3 Keogh05 0.21 0.6146 76MCM1_Alpha sir2 Meneghini03 -0.21 0.6149 106DAL81_RAPA SIN3 Hughes00 0.21 0.6154 95DAL82_RAPA hat2_vs._hat1Rosaleny05 0.21 0.6155 50STE12_YPD PCH1 Hughes00 -0.21 0.6156 51STE12_BUT90 Deaf3 Keogh05 -0.21 0.6156 74CIN5_H2O2Hi WT_V161R_L Chitikila_02 0.21 0.6161 78STE12_YPD EAF5 Krogan04 -0.21 0.6162 50STE12_BUT90 DT_N69S Chitikila_02 -0.21 0.6162 67PUT3_H2O2Lo rsc30_null Angus-Hill_01 -0.21 0.6163 87TYE7_YPD SWD2 Mnaimneh_04 0.21 0.6164 56MGA1_YPD WT Durant06 0.2 0.6169 58TYE7_YPD Ddep1 Keogh05 -0.2 0.617 52DAL81_RAPA Dsds3 Keogh05 0.2 0.617 86HAP1_YPD spt3 Huisinga04 0.2 0.617 139AFT2_H2O2Hi H3_1-28 Sabet04 0.2 0.6171 57RCS1_H2O2LoMED2_haploid Hughes00 0.2 0.6172 256MBP1_H2O2LoARD1 Hughes00 0.2 0.6176 58RIM101_H2O2Loume6_del Bernstein_00_affydeletions0.2 0.6176 40SKN7_H2O2LoSIN3 Hughes00 0.2 0.6176 185SUT1_YPD ISW2 Hughes00 -0.2 0.6178 69CIN5_H2O2Hi 0.1%_MMS Attikum04 0.2 0.6179 61OAF1_YPD H3KQ Sabet04 0.2 0.6181 55RIM101_H2O2Lohpa2D_taf1-ts2Durant06 -0.2 0.6184 31STP1_SM Set1_del Bernstein02 -0.2 0.6185 67SWI6_YPD ubp10 Orlandi04 0.2 0.6186 103ACE2_YPD TUP1_haploid Hughes00 0.2 0.6186 80RCS1_H2O2Hi TAF2 Mnaimneh_04 0.2 0.6187 52MCM1_Alpha WT_V161R_K Chitikila_02 0.2 0.6189 96MSN4_RAPA _SWC2_(VPS72)Krogan04 -0.2 0.6197 50ACE2_YPD hos3_del Bernstein_00_affydeletions0.2 0.6197 73OAF1_YPD SWD2 Mnaimneh_04 0.2 0.6199 59PHO4_YPD Deaf3 Keogh05 0.2 0.6202 61RLM1_YPD Set1_del Bernstein02 0.2 0.6202 52STE12_YPD HDA1 Hughes00 -0.2 0.6202 54CBF1_SM sap30_del Bernstein_00_affydeletions0.2 0.6203 264MCM1_YPD VID21 Krogan04 0.2 0.6204 71MSN2_H2O2HiWT_TAF1_SPT3Huisinga04 -0.2 0.6208 77CBF1_SM taf1-ts2_SPT3 Huisinga04 0.2 0.6209 264RCS1_H2O2LoHTZ1 Krogan04 -0.2 0.6209 239REB1_H2O2Hi Drxt1 Keogh05 0.2 0.621 59ABF1_YPD Hda1_del Bernstein02 -0.2 0.6211 266UME6_H2O2HiIES6 Hughes00 -0.2 0.6212 100GCR2_SM set1 Boa03 0.2 0.6217 54MBP1_H2O2Losir4 Orlandi04 0.2 0.6217 34CIN5_YPD sas3D Durant06 0.2 0.6219 112RTG3_RAPA isw2_rpd3 Fazzio01 -0.2 0.6219 51

GCN4_RAPA htz1_hmr Meneghini03 0.2 0.6221 156MSN2_H2O2Hispt10 Eriksson05 -0.2 0.6224 79STE12_YPD IES6 Hughes00 0.2 0.6225 53RPN4_H2O2LoUBP8 Ingvarsdottir05 0.2 0.6228 92FKH2_H2O2Hi YNG2 Mnaimneh_04 -0.2 0.6233 106OAF1_YPD elp3D_taf1-ts2Durant06 -0.2 0.6235 49SUM1_YPD swi1_minimal_medium_experimentSudarsanam00 -0.2 0.6236 58HSF1_H2O2LoDT_V71E Chitikila_02 0.2 0.6241 100PUT3_H2O2Lo HIR2 Hughes00 0.2 0.6243 85FKH2_YPD hpa2D Durant06 -0.2 0.6246 99RLM1_YPD WT_Null_L Chitikila_02 0.2 0.6248 49HSF1_H2O2Hi UBP8 Ingvarsdottir05 0.2 0.625 117PHD1_YPD WT_V71E Chitikila_02 -0.2 0.6251 54ACE2_YPD DT_V71R Chitikila_02 -0.2 0.6252 75CIN5_H2O2Hi taf1-ts2_GCN5Huisinga04 -0.2 0.6253 76FKH2_YPD ZDS1 Hughes00 -0.2 0.6255 120RTG3_RAPA WT Durant06 0.2 0.6259 50REB1_H2O2Hi elp3D_taf1-ts2Durant06 -0.2 0.6259 44YAP7_H2O2Hi _SWC2_(VPS72)Krogan04 0.2 0.6259 129STP1_SM IES6 Hughes00 -0.2 0.6263 66CIN5_H2O2Lo hmr Meneghini03 0.2 0.6263 121MGA1_YPD HST3 Hughes00 -0.2 0.6263 62YAP6_H2O2Lo rpd3_del Sabet04 -0.2 0.6265 51DIG1_BUT14 spt10 Eriksson05 -0.2 0.6268 63TYE7_YPD sas3D_taf1-ts2Durant06 0.2 0.6272 50PHO4_YPD gcn5D Durant06 -0.2 0.6273 62HSF1_H2O2Lo isw2_sin3_vs._sin3Fazzio01 0.2 0.6273 97OAF1_YPD UBP8 Ingvarsdottir05 -0.2 0.6273 52DAL81_RAPA hht2K9131823GMartin04 0.2 0.6274 74MCM1_Alpha sap30_del Bernstein_00_affydeletions-0.2 0.628 98STE12_BUT14 SAP30 Hughes00 0.2 0.628 128MCM1_YPD ume6_del Bernstein_00_affydeletions-0.2 0.6281 69STE12_Alpha EAF7 Krogan04 0.2 0.6283 105STE12_BUT14 isw2 Fazzio01 0.2 0.6283 126UME6_YPD swi1_minimal_medium_experimentSudarsanam00 -0.2 0.6287 131MBP1_H2O2Losir2 Meneghini03 -0.2 0.6287 57SKN7_YPD Dsin3 Keogh05 0.2 0.629 55SWI4_YPD set1 Boa03 -0.2 0.629 154DAL82_SM hat1D Durant06 -0.2 0.6292 44MBP1_H2O2Losin3_del Bernstein_00_affydeletions-0.2 0.6296 55PHO4_YPD SIN3 Hughes00 0.2 0.6298 71ACE2_YPD rpd3_c.i. Fazzio01 -0.2 0.6298 74SKN7_YPD isw2 Fazzio01 -0.2 0.63 63UME6_YPD HST3 Hughes00 -0.2 0.63 130SKN7_H2O2Loarp8_+_0.1%_MMS_vs._arp8Attikum04 -0.2 0.6305 148HSF1_H2O2Hi hht2K9131823GMartin04 0.2 0.6307 99ROX1_YPD WT_WT Chitikila_02 -0.2 0.6308 64GLN3_RAPA MOT1-42 Dasgupta02 0.2 0.6308 67XBP1_H2O2Lo taf1-ts2_gcn5 Huisinga04 0.2 0.6309 63DIG1_BUT14 gcn5D Durant06 -0.2 0.6309 53HAP4_YPD SAP30 Hughes00 -0.19 0.6311 67MBP1_H2O2Hi IOC4 Hughes00 0.19 0.6312 131FKH2_YPD WT_TAF1_GCN5Huisinga04 0.19 0.6312 120

GCN4_RAPA rsc3-2 Angus-Hill_01 0.19 0.6313 151HAP4_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.19 0.6313 64HSF1_H2O2Hi Dsds3 Keogh05 0.19 0.6319 113XBP1_H2O2Lo ino80 Attikum04 0.19 0.6319 41FKH2_H2O2Hi ISW1_ISW2 Hughes00 0.19 0.632 106FKH2_YPD elp3D_taf1-ts2Durant06 0.19 0.6321 90FKH2_YPD ISW2 Hughes00 0.19 0.6324 121PUT3_H2O2Lo Dsap30 Keogh05 -0.19 0.6325 86ROX1_YPD Dsin3 Keogh05 -0.19 0.6327 57SKN7_H2O2Hi taf1-ts2_spt3 Huisinga04 -0.19 0.6329 91MBP1_H2O2Hi arp8 Attikum04 -0.19 0.6334 102UME6_H2O2Hihtz1_del Mizuguch04 0.19 0.6336 102YAP6_YPD HAT2 Hughes00 -0.19 0.6337 91SUM1_YPD swi1_rich_medium_experimentSudarsanam00 0.19 0.6338 58MCM1_Alpha WT_V71E Chitikila_02 0.19 0.6338 88YAP7_H2O2Lo snf2_minimal_medium_experimentSudarsanam00 0.19 0.6341 151STP1_SM hht2_K4G Martin04 0.19 0.6345 51ROX1_YPD HIR2 Hughes00 0.19 0.6347 65CIN5_H2O2Hi hat2_vs._hat1Rosaleny05 0.19 0.6348 77SWI4_YPD sin3_del Bernstein_00_affydeletions-0.19 0.6352 144GCN4_RAPA WT_F182V Chitikila_02 -0.19 0.6359 126DIG1_Alpha SSN6_haploid Hughes00 0.19 0.6362 59ACE2_YPD hht2_K27G Martin04 -0.19 0.6363 67AFT2_H2O2Hi delta_ssd1 Kaeberlein04 0.19 0.6364 61STE12_BUT14 hat2_vs._YPH250Rosaleny05 0.19 0.6364 121STP1_SM WT_V161R_K Chitikila_02 -0.19 0.6366 61DAL82_SM PCH1 Hughes00 0.19 0.6367 55YAP6_H2O2Hi _SWC2_(VPS72)Krogan04 -0.19 0.6371 74DAL81_RAPA DT_V161R_L Chitikila_02 -0.19 0.6372 87AFT2_H2O2Hi htz1 Meneghini03 -0.19 0.6374 59YAP7_H2O2Hi snf2_rich_medium_experimentSudarsanam00 -0.19 0.6374 140DAL82_RAPA hda1_del Bernstein_00_affydeletions-0.19 0.6376 51FKH1_YPD YNG2 Mnaimneh_04 -0.19 0.6376 142FKH1_YPD ino80_del Mizuguch04 0.19 0.6376 142OAF1_YPD hos3_del Bernstein_00_affydeletions-0.19 0.6376 52MCM1_YPD taf1-ts2 Durant06 0.19 0.6381 74PHO4_YPD isw2_rpd3_vs._rpd3Fazzio01 0.19 0.6383 71SUM1_YPD taf1-ts2_spt3_E240KHuisinga04 -0.19 0.6383 46HAP1_YPD hpa2D Durant06 -0.19 0.6384 120YAP1_YPD DT_WT Chitikila_02 -0.19 0.6385 67MBP1_YPD isw2 Fazzio01 0.19 0.6386 123RPN4_H2O2LoWT Durant06 -0.19 0.639 92MBP1_H2O2Hihmr Meneghini03 -0.19 0.6391 131PHO4_YPD Dsds3 Keogh05 0.19 0.6393 61MCM1_YPD swr1 Meneghini03 -0.19 0.6393 62FKH2_H2O2Hi HTZ1 Krogan04 0.19 0.6394 98MBP1_YPD Dsap30 Keogh05 0.19 0.6397 125PHD1_YPD RSC8 Mnaimneh_04 -0.19 0.6399 67STE12_BUT90 snf2_rich_medium_experimentSudarsanam00 -0.19 0.6401 77DAL81_RAPA SWC6_(VPS71)Krogan04 0.19 0.6403 79GCN4_SM hda1_del Bernstein_00_affydeletions0.19 0.6405 184HSF1_H2O2LoSWD2 Mnaimneh_04 0.19 0.6406 100FKH1_YPD esa1-414 Durant06 0.19 0.6407 127

ASH1_BUT14 0.1%_MMS Attikum04 -0.19 0.6409 35SKN7_H2O2Hi ISW1_ISW2 Hughes00 0.19 0.6411 97YAP6_H2O2Lo RSC8 Mnaimneh_04 0.19 0.6411 59YAP7_H2O2Hi TAF2 Mnaimneh_04 0.19 0.6414 140STE12_BUT14 hos2_del Bernstein_00_affydeletions0.19 0.6416 120HSF1_H2O2Hi Drpd3 Keogh05 0.19 0.6419 115ROX1_YPD WT_F182V Chitikila_02 -0.19 0.642 59REB1_YPD HTZ1 Krogan04 0.19 0.6423 132CBF1_SM Drco1 Keogh05 0.19 0.6426 263GCR2_SM H3KQ Sabet04 0.19 0.6433 54RTG3_RAPA isw2_c.i._rpd3_c.i.Fazzio01 -0.19 0.6436 51ACE2_YPD HDA1 Hughes00 0.19 0.6438 80RTG3_RAPA Dsin3 Keogh05 0.19 0.6439 46STE12_BUT90 rpd3_del Sabet04 -0.19 0.6441 74SWI6_YPD taf1-ts2_25C Huisinga04 0.19 0.6444 142YAP6_H2O2Hi IES6 Hughes00 -0.19 0.6448 78PHD1_BUT90 Dsap30 Keogh05 -0.19 0.6449 105YAP6_H2O2Lo H3KQ Sabet04 0.19 0.645 51FKH2_YPD WT_Null_K Chitikila_02 -0.19 0.6452 115MBP1_YPD ISW1_ISW2 Hughes00 0.19 0.6454 130RTG3_RAPA HTZ1 Krogan04 -0.19 0.6456 49AFT2_H2O2Hi gcn5D_taf1-ts2Durant06 0.18 0.6457 58SKN7_YPD ISW2 Hughes00 -0.18 0.6458 66GLN3_RAPA taf1-ts2_25C Huisinga04 0.18 0.6458 62AFT2_H2O2Hi hmr Meneghini03 0.18 0.6458 60PHO4_YPD ARP4 Mnaimneh_04 0.18 0.6459 72SUT1_YPD BUR6 Geisberg_01 0.18 0.6462 61CIN5_H2O2Lo SSD1-V Kaeberlein04 0.18 0.6464 127MCM1_Alpha DT_V71E Chitikila_02 0.18 0.6464 101UME6_YPD hos3_del Bernstein_00_affydeletions-0.18 0.6471 122FKH2_YPD hos3_del Bernstein_00_affydeletions0.18 0.6472 116RCS1_H2O2LoH3KQ Sabet04 -0.18 0.6474 253SKN7_YPD Dsds3 Keogh05 0.18 0.6478 57RIM101_H2O2LoWT_F182V Chitikila_02 0.18 0.6479 40PHO4_YPD taf1-ts2_gcn5 Huisinga04 -0.18 0.6482 69SUT1_YPD taf1-ts2_25C Huisinga04 -0.18 0.6482 65RTG3_RAPA hht2_K4914182327GMartin04 0.18 0.6482 42RCS1_H2O2Hi taf1-ts2_gcn5 Huisinga04 0.18 0.6483 47UME6_H2O2Hispt3 Huisinga04 0.18 0.6485 95YAP6_H2O2Lo isw2_ume6 Fazzio01 0.18 0.6485 57MBP1_H2O2LoSIR1 Hughes00 -0.18 0.6486 58YAP1_YPD hht2_K4G Martin04 -0.18 0.6487 58HAP4_YPD sas3D_taf1-ts2Durant06 0.18 0.6488 60PUT3_H2O2Lo sin3_del Bernstein_00_affydeletions-0.18 0.6489 79CIN5_H2O2Lo gcn5_KQL Huisinga04 0.18 0.6491 113YAP6_H2O2Lo rsc3-2 Angus-Hill_01 0.18 0.6494 57STE12_Alpha ZDS1 Hughes00 0.18 0.6495 113SUT1_YPD swr1 Meneghini03 0.18 0.65 48GCN4_YPD RSC8 Mnaimneh_04 -0.18 0.6501 75HSF1_H2O2Lohat2_vs._YPH250Rosaleny05 -0.18 0.6502 99YAP7_H2O2Lo Ddep1 Keogh05 0.18 0.6506 136HSF1_H2O2LoMED2_haploid Hughes00 0.18 0.6507 98STE12_Alpha ubp10 Orlandi04 -0.18 0.6507 69

ACE2_YPD snf2_rich_medium_experimentSudarsanam00 -0.18 0.6514 80RTG3_RAPA SSN6_haploid Hughes00 0.18 0.6516 51AFT2_H2O2Hi hht2_K4914182327GMartin04 0.18 0.6516 45DIG1_BUT14 YNG2 Mnaimneh_04 -0.18 0.6516 63TYE7_YPD DT_WT Chitikila_02 -0.18 0.6523 54REB1_YPD hat1D Durant06 -0.18 0.6528 114HAP1_YPD MOT1-14 Dasgupta02 0.18 0.653 141SKN7_YPD H4_2-26 Sabet04 0.18 0.6532 62PHO4_YPD ino80 Attikum04 -0.18 0.6534 58REB1_YPD Ddep1 Keogh05 0.18 0.6535 133DAL81_RAPA arp8_+_0.1%_MMS_vs._arp8Attikum04 0.18 0.6535 78RLM1_YPD hht2K9131823GMartin04 0.18 0.6536 42YAP7_H2O2Lo sin3_del Bernstein_00_affydeletions-0.18 0.6537 144PHO4_YPD Ddep1 Keogh05 -0.18 0.6538 66RTG3_RAPA snf2_minimal_medium_experimentSudarsanam00 -0.18 0.6538 52PHO4_YPD SIR4 Hughes00 -0.18 0.6539 71SOK2_BUT14 ubp10sir4 Orlandi04 -0.18 0.6539 40FKH2_H2O2Hi sas3D Durant06 -0.18 0.6548 88MSN4_RAPA DT_N69R Chitikila_02 0.18 0.6553 49PUT3_H2O2Lo hht2K9131823GMartin04 -0.18 0.6555 67RTG3_RAPA WT_V71R Chitikila_02 -0.18 0.6556 50REB1_YPD gcn5_KQL Huisinga04 0.18 0.6557 123SKN7_H2O2Hi isw2_sin3_vs._sin3Fazzio01 0.18 0.6557 95AFT2_H2O2Lo set1 Boa03 0.18 0.6557 97RCS1_H2O2Losir4 Orlandi04 -0.18 0.656 191GCN4_SM Set1_del Bernstein02 0.18 0.6561 188SUM1_YPD arp8 Attikum04 0.18 0.6562 31STE12_YPD set1 Boa03 0.18 0.6565 52TYE7_YPD H4_2-26 Sabet04 -0.18 0.6565 55HAP1_YPD snf2_rich_medium_experimentSudarsanam00 -0.18 0.6565 141HAP4_YPD ino80 Attikum04 0.18 0.6565 48TYE7_YPD IES6 Hughes00 0.18 0.6566 56ROX1_YPD IOC4 Hughes00 0.18 0.6568 67RCS1_H2O2Hi Dume1 Keogh05 -0.18 0.6569 46GCN4_RAPA SWC6_(VPS71)Krogan04 0.18 0.6571 148REB1_H2O2Hi esa1-414_taf1-ts2Durant06 -0.18 0.6571 55OAF1_YPD sin3_del Bernstein_00_affydeletions0.18 0.6571 51SUT1_YPD SWR1 Krogan04 -0.18 0.6573 65STP1_SM hht2_K914182327GMartin04 -0.18 0.6574 54YAP7_H2O2Lo snf2_rich_medium_experimentSudarsanam00 0.18 0.6574 151YAP7_H2O2Lo hat2_vs._hat1Rosaleny05 -0.18 0.6575 148CIN5_H2O2Hi Drco1 Keogh05 0.18 0.6576 76ROX1_YPD ZDS1 Hughes00 -0.18 0.6577 66DAL82_SM DT_V71E Chitikila_02 0.18 0.6577 53RIM101_H2O2Loarp8 Attikum04 0.18 0.6578 32YAP7_H2O2Hi WT_N69S Chitikila_02 -0.18 0.6579 128FKH1_YPD SIR4 Hughes00 -0.18 0.6579 141STE12_YPD spt10 Eriksson05 -0.18 0.658 52SUM1_YPD SSD1-V Kaeberlein04 -0.18 0.658 57DAL82_SM TAF2 Mnaimneh_04 0.18 0.6582 55AFT2_H2O2Lo Ddep1 Keogh05 0.18 0.6582 88ROX1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.18 0.6583 47SKN7_H2O2HiDT_V71E Chitikila_02 -0.18 0.6584 94

FKH2_H2O2Hi set1 Boa03 0.18 0.6585 103SKN7_H2O2Hi hat2_vs._hat1Rosaleny05 0.18 0.6585 94SUM1_YPD htz1 Meneghini03 -0.18 0.6588 55DAL82_RAPA hat1D_taf1-ts2Durant06 0.18 0.6589 39CIN5_H2O2Hi RSC8 Mnaimneh_04 0.18 0.6589 80FKH2_H2O2Hi MOT1-14 Dasgupta02 0.18 0.6597 105DIG1_Alpha ume6_del Bernstein_00_affydeletions-0.18 0.6597 54MCM1_Alpha DT_V71R Chitikila_02 0.18 0.6598 101MBP1_H2O2Lohmr Meneghini03 -0.18 0.6602 57AFT2_H2O2Lo htz1 Meneghini03 -0.18 0.6605 95GCN4_YPD hht2_K914182327GMartin04 -0.17 0.6612 65MGA1_YPD swi1_minimal_medium_experimentSudarsanam00 -0.17 0.6612 62TYE7_YPD WT_TAF1_SPT3Huisinga04 0.17 0.6613 53CIN5_H2O2Hi H3KQ Sabet04 0.17 0.6614 74FKH1_YPD htz1_del Mizuguch04 0.17 0.6614 142STP1_SM WT_N69S Chitikila_02 -0.17 0.6616 61PHD1_YPD TAF2 Mnaimneh_04 0.17 0.6622 67PHO4_YPD H4_2-26 Sabet04 0.17 0.6622 70TYE7_YPD SSN6_haploid Hughes00 0.17 0.6622 55SWI5_YPD DT_V71R Chitikila_02 0.17 0.6624 90SUM1_YPD isw2_rpd3_vs._rpd3Fazzio01 0.17 0.6625 59DIG1_BUT14 isw2_rpd3 Fazzio01 0.17 0.6626 63RIM101_H2O2LoSIR4 Hughes00 -0.17 0.6627 53GCR2_SM htz1_del Mizuguch04 0.17 0.663 54PHO4_YPD htz1 Meneghini03 0.17 0.6631 71PHO4_YPD Rpd3_del Bernstein02 0.17 0.6631 69RCS1_H2O2Hi sas3D_taf1-ts2Durant06 0.17 0.6631 48STE12_BUT90 set1 Boa03 -0.17 0.6632 76SWI6_YPD H4_2-26 Sabet04 -0.17 0.6635 148YAP1_YPD Ddep1 Keogh05 0.17 0.6639 66REB1_H2O2Hi sir2 Meneghini03 -0.17 0.6639 56HSF1_H2O2Hi Ddep1 Keogh05 0.17 0.6641 115MCM1_Alpha htz1_sir2 Meneghini03 0.17 0.6642 106STP1_SM WT_F182V Chitikila_02 -0.17 0.6643 50DAL82_RAPA hht2_K4914182327GMartin04 0.17 0.6643 39FKH1_YPD WT_Null_L Chitikila_02 -0.17 0.6644 131AFT2_H2O2Hi esa1-414 Durant06 -0.17 0.6647 57HAP1_YPD sin3 Fazzio01 -0.17 0.6647 136GCR2_SM snf2_rich_medium_experimentSudarsanam00 -0.17 0.6648 54RCS1_H2O2LoSIR4 Hughes00 -0.17 0.6648 255RIM101_H2O2LoWT_V71E Chitikila_02 0.17 0.6648 42MCM1_Alpha SPT8 Ingvarsdottir05 0.17 0.6649 96ASH1_BUT14 arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.17 0.6653 35CIN5_H2O2Hi rsc3-2 Angus-Hill_01 0.17 0.6654 78YAP6_H2O2Lo _SWC2_(VPS72)Krogan04 -0.17 0.6655 54PHO4_YPD hht2K9131823GMartin04 0.17 0.6656 62OAF1_YPD snf2_rich_medium_experimentSudarsanam00 0.17 0.6656 57HAP1_YPD ISW1_ISW2 Hughes00 -0.17 0.6657 140STE12_Alpha PCH1 Hughes00 0.17 0.6659 112STE12_Alpha rsc3-2 Angus-Hill_01 0.17 0.666 112SKN7_YPD ino80 Attikum04 0.17 0.6665 46NRG1_H2O2HiDdep1 Keogh05 0.17 0.6667 120FKH2_H2O2Hi WT_Null_K Chitikila_02 -0.17 0.6669 102

MBP1_H2O2LoVID21 Krogan04 -0.17 0.6669 55RLM1_YPD RAD6_haploid Hughes00 -0.17 0.6674 51MCM1_Alpha ZDS1 Hughes00 -0.17 0.6674 103REB1_YPD ume6_del Bernstein_00_affydeletions0.17 0.6675 138FKH2_H2O2Hi WT_TAF1_GCN5Huisinga04 -0.17 0.6676 106STE12_Alpha VID21 Krogan04 0.17 0.6677 98SUT1_YPD DT_V71E Chitikila_02 0.17 0.6679 67SWI5_YPD Drco1 Keogh05 0.17 0.6679 96STE12_BUT14 hat1D_taf1-ts2Durant06 0.17 0.6679 106GCR2_SM MOT1-14 Dasgupta02 -0.17 0.6681 53HSF1_H2O2Hi SWC6_(VPS71)Krogan04 0.17 0.6681 110UME6_H2O2Hihtz1_hmr Meneghini03 0.17 0.6681 97PHD1_YPD HAT2 Hughes00 0.17 0.6682 66YAP7_H2O2Hi htz1 Meneghini03 0.17 0.6682 134NRG1_YPD sir4 Orlandi04 0.17 0.6682 19AFT2_H2O2Lo esa1-414_taf1-ts2Durant06 0.17 0.6683 87UME6_H2O2Hihht2K9131823GMartin04 0.17 0.6687 76DIG1_BUT14 rpd3 Fazzio01 -0.17 0.6688 63FKH1_YPD PCH1 Hughes00 -0.17 0.6688 141FKH2_YPD set1 Boa03 -0.17 0.6689 119OAF1_YPD VID21 Krogan04 -0.17 0.6691 53SUM1_YPD EPL1 Mnaimneh_04 -0.17 0.6694 59RCS1_H2O2Hi EPL1 Mnaimneh_04 -0.17 0.6696 52REB1_H2O2Hi ubp10 Orlandi04 -0.17 0.6702 37UME6_H2O2HiWT_N69R Chitikila_02 -0.17 0.6703 90RCS1_H2O2Hi elp3D Durant06 0.17 0.6711 44AFT2_H2O2Hi SPT3 Ingvarsdottir05 -0.17 0.6714 53MSN4_H2O2HiWT_Null_L Chitikila_02 -0.17 0.6714 65FKH1_YPD spt3_E240K Huisinga04 -0.17 0.6714 134CIN5_H2O2Lo isw2_sin3_vs._sin3Fazzio01 0.17 0.6718 125DIG1_Alpha H3_1-28 Sabet04 -0.17 0.6718 56SWI5_YPD DT_V161R_L Chitikila_02 -0.17 0.6729 94DAL82_SM YNG2 Krogan04 0.17 0.673 48GLN3_RAPA DT_V161R_K Chitikila_02 -0.17 0.673 65DIG1_BUT14 BUR6 Geisberg_01 0.17 0.673 60STE12_BUT14 HAT2 Hughes00 0.17 0.6732 125MBP1_YPD Dpho23 Keogh05 0.17 0.674 129MSN4_RAPA DT_Null Chitikila_02 -0.17 0.6743 51GCN4_RAPA isw2_c.i._rpd3_c.i.Fazzio01 0.17 0.6745 155CBF1_SM hht2_K914182327GMartin04 0.17 0.6746 224PHO4_YPD SWR1 Krogan04 0.17 0.675 65PUT3_H2O2Lo spt3 Huisinga04 -0.17 0.6752 82OAF1_YPD Dsap30 Keogh05 -0.17 0.6752 54SWI6_YPD hpa2D_taf1-ts2Durant06 -0.17 0.6753 117SKN7_H2O2HiDrxt2 Keogh05 -0.17 0.6754 95CBF1_SM WT_Null_K Chitikila_02 0.17 0.6757 266CIN5_H2O2Lo spt10_del Xu05 0.17 0.6757 125RLM1_YPD H4_2-26 Sabet04 -0.17 0.6759 50DAL82_RAPA H4KQ Sabet04 0.17 0.6759 53RCS1_H2O2Lohtz1_hmr Meneghini03 -0.17 0.6759 248HSF1_H2O2Hi Drxt1 Keogh05 0.16 0.6762 123OAF1_YPD spt10_del Xu05 0.16 0.6763 59MSN4_RAPA H4KQ Sabet04 -0.16 0.6764 52

FKH2_H2O2Hi DT_V71R Chitikila_02 0.16 0.6765 102MSN4_H2O2Hiisw2_rpd3 Fazzio01 0.16 0.6766 68NDD1_YPD rpd3_del Sabet04 0.16 0.6771 83MCM1_YPD HAT2 Hughes00 -0.16 0.6773 77ACE2_YPD Hda1_del Bernstein02 -0.16 0.6775 80FKH2_H2O2Hi Deaf3 Keogh05 0.16 0.6776 94DAL82_SM WT_Null_K Chitikila_02 0.16 0.6784 52STE12_Alpha TAF2 Mnaimneh_04 -0.16 0.6786 115DAL82_RAPA WT_V161R_K Chitikila_02 -0.16 0.6787 53DIG1_BUT14 ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.16 0.679 55YAP1_YPD RSC8 Mnaimneh_04 0.16 0.6792 72FKH2_YPD MOT1-14 Dasgupta02 -0.16 0.6792 121STP1_SM WT Durant06 -0.16 0.6795 65YAP6_H2O2Lo ARP4 Mnaimneh_04 -0.16 0.6796 59HAP4_YPD WT Durant06 -0.16 0.68 65NRG1_YPD arp8 Attikum04 0.16 0.6801 36RLM1_YPD MOT1-14 Dasgupta02 0.16 0.6802 53MSN4_H2O2HiDume1 Keogh05 0.16 0.6805 66NRG1_YPD hht2_K914182327GMartin04 0.16 0.6805 31SWI4_YPD SIR3 Hughes00 0.16 0.6809 155MCM1_YPD esa1-414_taf1-ts2Durant06 0.16 0.6809 64GCN4_RAPA rpd3_c.i. Fazzio01 -0.16 0.6811 154STE12_BUT90 ume6_del Bernstein_00_affydeletions-0.16 0.6811 72TYE7_YPD htz1 Meneghini03 0.16 0.6812 54UME6_H2O2HiDeaf3 Keogh05 0.16 0.6816 93SUM1_YPD SIR1 Hughes00 0.16 0.682 59STE12_BUT14 SWD2 Mnaimneh_04 -0.16 0.682 128ROX1_YPD rpd3_del Sabet04 -0.16 0.6825 58HSF1_H2O2Hi ISW2 Hughes00 -0.16 0.6827 122MCM1_Alpha WT Durant06 -0.16 0.6829 100GCR2_SM SAP30 Hughes00 -0.16 0.683 54DIG1_BUT14 WT_V71E Chitikila_02 -0.16 0.683 53DAL82_SM Drpd3 Keogh05 0.16 0.6834 46MSN2_H2O2Hiarp8 Attikum04 -0.16 0.6834 62DIG1_Alpha sir4 Orlandi04 0.16 0.6835 33NDD1_YPD hat2_vs._hat1Rosaleny05 -0.16 0.6837 81HSF1_H2O2Hi ARD1 Hughes00 0.16 0.6839 121PHD1_YPD sas3D_taf1-ts2Durant06 0.16 0.6843 57ACE2_YPD rpd3_del Sabet04 -0.16 0.6843 77GCN4_YPD hmr Meneghini03 0.16 0.6844 72YAP1_YPD SWC6_(VPS71)Krogan04 0.16 0.6845 67STE12_BUT90 ubp10 Orlandi04 0.16 0.6845 61CBF1_SM hat1_vs.YPH250Rosaleny05 -0.16 0.6846 255NRG1_H2O2HiDrpd3 Keogh05 0.16 0.6846 116MCM1_Alpha taf1-ts2_spt3_E240KHuisinga04 0.16 0.6847 95SOK2_BUT14 set1 Boa03 0.16 0.6847 72GLN3_RAPA hat1_vs.YPH250Rosaleny05 0.16 0.6848 63HSF1_H2O2Hi ZDS1 Hughes00 0.16 0.6848 123STP1_SM isw2_ume6 Fazzio01 0.16 0.6854 67DAL82_SM rsc3-2 Angus-Hill_01 0.16 0.6856 54STP1_SM isw2_sin3_vs._sin3Fazzio01 -0.16 0.6857 67RTG3_RAPA delta_ssd1 Kaeberlein04 -0.16 0.6858 51MSN2_H2O2HiWT_Null_L Chitikila_02 -0.16 0.6858 73

FKH1_YPD hos3_del Bernstein_00_affydeletions0.16 0.6862 136GCR2_SM hat1_vs.YPH250Rosaleny05 -0.16 0.6863 50RTG3_RAPA WT_F182V Chitikila_02 -0.16 0.6863 41YAP7_H2O2Lo ume6 Fazzio01 -0.16 0.6863 148SUM1_YPD PCH1 Hughes00 0.16 0.6864 58SUT1_YPD HST3 Hughes00 0.16 0.6866 68NRG1_YPD taf1-ts2_gcn5 Huisinga04 0.16 0.6866 68DAL81_RAPA TAF2 Mnaimneh_04 -0.16 0.6868 95YAP6_H2O2Lo H4_2-26 Sabet04 0.16 0.6871 51PHD1_YPD WT_Null_K Chitikila_02 -0.16 0.6874 65GLN3_RAPA rpd3_H4KQ_v_H4KQSabet04 -0.16 0.6875 66MCM1_YPD htz1 Meneghini03 0.16 0.6876 77STE12_BUT14 spt10 Eriksson05 -0.16 0.6879 124CBF1_SM hht2_K4914182327GMartin04 0.16 0.6881 231SWI4_YPD rpd3_H3dN_v_H3dNSabet04 -0.16 0.6883 151FKH2_YPD spt3_E240K Huisinga04 -0.16 0.6883 111UME6_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 0.16 0.6884 88AFT2_H2O2Hi HDA1 Hughes00 0.16 0.6886 61GLN3_RAPA sin3_del Bernstein_00_affydeletions-0.16 0.6887 63SWI5_YPD WT_WT Chitikila_02 -0.16 0.6888 93DIG1_BUT14 HIR2 Hughes00 -0.16 0.6888 61REB1_H2O2Hi Dsds3 Keogh05 -0.16 0.6893 53MCM1_Alpha rpd3_H3dN_v_H3dNSabet04 -0.16 0.6893 103MBP1_H2O2LoWT_F182V Chitikila_02 -0.16 0.6894 37AFT2_H2O2Hi DT_Null Chitikila_02 0.16 0.6897 59OAF1_YPD htz1_del Mizuguch04 -0.16 0.6897 59SUM1_YPD gcn5 Huisinga04 0.16 0.6898 51NRG1_YPD SIR3 Hughes00 0.16 0.6899 71TYE7_YPD set1 Boa03 -0.16 0.6902 55DAL82_SM arp8 Attikum04 -0.16 0.6902 40NDD1_YPD hda1_del Bernstein_00_affydeletions0.16 0.6903 81UME6_YPD hmr Meneghini03 0.16 0.6906 127SWI6_YPD H3KQ Sabet04 -0.16 0.6907 148STE12_BUT14 hos3_del Bernstein_00_affydeletions-0.16 0.6907 121TYE7_YPD UBP8 Hughes00 0.16 0.691 55AFT2_H2O2Hi sir2 Meneghini03 0.16 0.6912 60STE12_BUT90 HTZ1 Krogan04 -0.16 0.6912 75TYE7_YPD H4KQ Sabet04 -0.16 0.6916 55FKH2_YPD DT_V71E Chitikila_02 -0.15 0.6919 117SWI5_YPD ZDS1 Hughes00 -0.15 0.6921 99RTG3_RAPA H4KQ Sabet04 0.15 0.6924 50HSF1_H2O2Hi SIR3 Hughes00 0.15 0.6924 122PHD1_YPD WT_V161R_L Chitikila_02 0.15 0.6925 64MBP1_H2O2Hihat2_vs._YPH250Rosaleny05 -0.15 0.693 126UME6_H2O2Hiswr1 Meneghini03 -0.15 0.693 80DIG1_BUT14 hat2_vs._hat1Rosaleny05 -0.15 0.6932 61SWI6_YPD hat1_vs.YPH250Rosaleny05 0.15 0.6933 146YAP7_H2O2Hi sas3D Durant06 0.15 0.6933 121MCM1_YPD Rpd3_del Bernstein02 0.15 0.6933 77AFT2_H2O2Hi Dsds3 Keogh05 0.15 0.6934 56ABF1_YPD ume6_del Bernstein_00_affydeletions-0.15 0.6937 254YAP7_H2O2Lo isw2_rpd3_vs._rpd3Fazzio01 0.15 0.6937 148ROX1_YPD hmr Meneghini03 -0.15 0.6938 66

TYE7_YPD SIR4 Hughes00 0.15 0.6939 54DAL82_RAPA IES6 Hughes00 0.15 0.6939 55CBF1_SM hat1D Durant06 -0.15 0.6943 200STE12_Alpha EAF5 Krogan04 0.15 0.6945 110AFT2_H2O2Hi MOT1-42 Dasgupta02 0.15 0.6946 61DAL82_RAPA Drxt1 Keogh05 -0.15 0.6948 55OAF1_YPD hht2_K4914182327GMartin04 -0.15 0.6949 45SWI4_YPD MOT1-14 Dasgupta02 0.15 0.6952 156MSN4_H2O2HiISW1_ISW2 Hughes00 0.15 0.6953 69PHD1_YPD SSD1-V Kaeberlein04 0.15 0.6955 66SWI5_YPD PCH1 Hughes00 -0.15 0.6957 100MSN4_RAPA SIR4 Hughes00 -0.15 0.6959 52SKN7_H2O2LoDrxt2 Keogh05 -0.15 0.696 180DIG1_BUT14 HAT2 Hughes00 0.15 0.696 63SWI5_YPD taf1-ts2_spt3 Huisinga04 -0.15 0.6961 94FKH2_H2O2Hi H4_2-26 Sabet04 -0.15 0.6961 102RLM1_YPD SWD2 Mnaimneh_04 0.15 0.6964 55REB1_H2O2Hi SIR4 Hughes00 0.15 0.6964 58DAL82_RAPA hat1_vs.YPH250Rosaleny05 0.15 0.6965 50FKH1_YPD BUR6 Geisberg_01 -0.15 0.6965 135FKH1_YPD WT_V71E Chitikila_02 -0.15 0.6972 120FKH2_YPD H3_1-28 Sabet04 0.15 0.6973 119DAL82_RAPA elp3D Durant06 0.15 0.6975 40UME6_YPD SGF11 Ingvarsdottir05 -0.15 0.6976 103MBP1_YPD rpd3_del Sabet04 0.15 0.6978 126NDD1_YPD Dsap30 Keogh05 0.15 0.698 82RCS1_H2O2LoDM_vs._YPH250Rosaleny05 -0.15 0.6982 239HAP1_YPD Dume1 Keogh05 0.15 0.6982 128NRG1_YPD SWD2 Mnaimneh_04 0.15 0.6983 72AFT2_H2O2Hi hht2_K27G Martin04 0.15 0.6984 43STE12_BUT90 SPT3 Ingvarsdottir05 0.15 0.6984 73UME6_YPD hpa2D Durant06 -0.15 0.6987 96FKH1_YPD ino80 Attikum04 -0.15 0.6987 113PUT3_H2O2Lo MOT1-14 Dasgupta02 -0.15 0.6988 88YAP7_H2O2Lo EPL1 Mnaimneh_04 -0.15 0.6988 152TYE7_YPD Dsap30 Keogh05 0.15 0.699 52STP1_SM UBP8 Hughes00 0.15 0.699 67SWI5_YPD delta_ssd1 Kaeberlein04 0.15 0.6991 100AFT2_H2O2Hi sas3D Durant06 -0.15 0.6991 51YAP6_H2O2Hi taf1-ts2_gcn5_KQLHuisinga04 0.15 0.6996 65XBP1_H2O2Lo hht2_K4G Martin04 0.15 0.6999 44GCR2_SM TUP1_haploid Hughes00 -0.15 0.7001 54YAP1_YPD isw2_c.i._rpd3_c.i.Fazzio01 -0.15 0.7002 68RTG3_RAPA SIR1 Hughes00 0.15 0.7002 51DAL82_SM H4_2-26 Sabet04 0.15 0.7006 50REB1_YPD 0.1%_MMS Attikum04 -0.15 0.701 115STE12_Alpha YNG2 Krogan04 0.15 0.7011 106YAP1_YPD hmr Meneghini03 0.15 0.7016 66HAP1_YPD DM_vs._YPH250Rosaleny05 0.15 0.7018 129GCN4_YPD htz1_hmr Meneghini03 0.15 0.7024 72MSN4_H2O2HiDT_N69R Chitikila_02 -0.15 0.7026 67ACE2_YPD SGF11 Ingvarsdottir05 -0.15 0.7027 68STE12_BUT14 ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.15 0.7028 108

GCN4_SM hmr Meneghini03 -0.15 0.7029 182PHO4_YPD elp3D Durant06 -0.15 0.7035 62YAP7_H2O2Hi DT_V71E Chitikila_02 -0.15 0.7036 139MSN4_RAPA Deaf3 Keogh05 -0.15 0.7038 49RLM1_YPD MOT1-42 Dasgupta02 -0.15 0.704 53CBF1_SM SAP30 Hughes00 0.15 0.704 275ROX1_YPD SGF11 Ingvarsdottir05 0.15 0.7042 57CIN5_YPD YAF9 Krogan04 -0.15 0.7042 139AFT2_H2O2Hi hat1D Durant06 -0.15 0.7042 46REB1_H2O2Hi Deaf3 Keogh05 -0.15 0.7042 55ABF1_YPD WT_Null_L Chitikila_02 -0.15 0.7044 248FKH2_H2O2Hi Set1_del Bernstein02 -0.15 0.705 103DAL81_RAPA hmr Meneghini03 0.15 0.7054 91FKH2_H2O2Hi hmr Meneghini03 0.15 0.7059 105MCM1_Alpha SGF11 Ingvarsdottir05 -0.15 0.706 88DAL82_SM EAF5 Krogan04 -0.15 0.7061 47MBP1_H2O2Loume6 Fazzio01 -0.15 0.7061 54SUM1_YPD ARP4 Mnaimneh_04 -0.15 0.7062 59DAL81_RAPA sin3_del Bernstein_00_affydeletions-0.15 0.7071 92RCS1_H2O2Hi Drco1 Keogh05 0.15 0.7071 48YAP1_YPD WT_TAF1_SPT3Huisinga04 0.15 0.7073 70HAP1_YPD hat1D Durant06 -0.15 0.7075 118MBP1_YPD sin3_del Bernstein_00_affydeletions0.15 0.7075 123RCS1_H2O2Lohtz1_del Mizuguch04 -0.15 0.7078 258FKH2_YPD HTZ1 Krogan04 0.15 0.7078 108DIG1_BUT14 Dsds3 Keogh05 -0.15 0.7079 61NRG1_YPD EPL1 Mnaimneh_04 -0.14 0.7081 72TYE7_YPD SIR2 Hughes00 0.14 0.7083 56NRG1_H2O2HiHAT2 Hughes00 -0.14 0.7088 124YAP6_H2O2Lo HAT2 Hughes00 -0.14 0.7088 57YAP1_YPD SWD2 Mnaimneh_04 0.14 0.7094 72MGA1_YPD sin3_del Bernstein_00_affydeletions-0.14 0.7098 60DAL82_RAPA Drpd3 Keogh05 -0.14 0.7099 48YAP7_H2O2Lo RAD6_haploid Hughes00 0.14 0.71 149DAL82_RAPA WT_F182V Chitikila_02 0.14 0.7101 42MCM1_YPD RSC8 Mnaimneh_04 0.14 0.7104 77DAL81_RAPA hht2_K49141823GMartin04 -0.14 0.7105 74MGA1_YPD IES6 Hughes00 -0.14 0.7106 62YAP1_YPD hht2_K49141823GMartin04 0.14 0.7107 58AFT2_H2O2Lo HIR2 Hughes00 0.14 0.7107 93HSF1_H2O2Loset1 Boa03 -0.14 0.7108 96MBP1_H2O2Lohos2_del Bernstein_00_affydeletions-0.14 0.7109 54MGA1_YPD spt3_E240K Huisinga04 0.14 0.711 56DAL81_RAPA ARD1 Hughes00 -0.14 0.7111 93RTG3_RAPA hht2K9131823GMartin04 0.14 0.7111 42MSN2_H2O2HiDrxt1 Keogh05 0.14 0.7113 77XBP1_H2O2Lo hat2_vs._YPH250Rosaleny05 0.14 0.7113 61OAF1_YPD hht2_K914182327GMartin04 -0.14 0.7113 44PHO4_YPD hpa2D Durant06 0.14 0.712 58CIN5_H2O2Hi EPL1 Mnaimneh_04 -0.14 0.7121 80DAL82_RAPA hht2_K914182327GMartin04 0.14 0.7122 38PUT3_H2O2Lo HTZ1 Krogan04 0.14 0.7122 83DAL81_RAPA hht2_K4914182327GMartin04 -0.14 0.7124 74

GCN4_YPD gcn5 Huisinga04 0.14 0.7126 74HSF1_H2O2Hi MOT1-42 Dasgupta02 0.14 0.7127 123STE12_YPD WT_Null_K Chitikila_02 0.14 0.7128 47REB1_H2O2Hi hat1D_taf1-ts2Durant06 -0.14 0.7128 49UME6_H2O2Hihat1_vs.YPH250Rosaleny05 -0.14 0.7129 95DIG1_Alpha isw2_ume6 Fazzio01 -0.14 0.713 59GLN3_RAPA hht2_K914182327GMartin04 0.14 0.7131 50DIG1_Alpha hpa2D_taf1-ts2Durant06 0.14 0.7131 34HAP4_YPD sap30_del Bernstein_00_affydeletions-0.14 0.7133 58CBF1_SM elp3D_taf1-ts2Durant06 0.14 0.7134 222AFT2_H2O2Lo IES6 Hughes00 -0.14 0.7135 97FKH2_YPD WT_F182V Chitikila_02 0.14 0.7139 102FKH1_YPD ISW1 Hughes00 0.14 0.7141 139FKH2_YPD BUR6 Geisberg_01 0.14 0.7141 117CIN5_H2O2Hi hmr Meneghini03 0.14 0.7142 79HSF1_H2O2Losnf2_rich_medium_experimentSudarsanam00 -0.14 0.7144 101STE12_BUT90 hda1_del Bernstein_00_affydeletions0.14 0.7144 72PHO4_YPD RPD3_haploid Hughes00 -0.14 0.7146 71CBF1_SM rpd3 Fazzio01 0.14 0.7146 272STP1_SM DT_N69S Chitikila_02 0.14 0.7146 62DAL81_RAPA HAT2 Hughes00 -0.14 0.7146 93CBF1_SM RAD6_haploid Hughes00 0.14 0.7147 276DAL81_RAPA Drxt2 Keogh05 0.14 0.7151 90STE12_YPD DM_vs._YPH250Rosaleny05 0.14 0.7152 49STE12_YPD SSN6_haploid Hughes00 -0.14 0.7153 52MBP1_H2O2LoDsap30 Keogh05 -0.14 0.7153 54STE12_Alpha SIR4 Hughes00 0.14 0.7153 114MGA1_YPD MOT1-42 Dasgupta02 -0.14 0.7153 62SWI5_YPD rpd3_H3dN_v_H3dNSabet04 -0.14 0.716 93MCM1_Alpha swi1_minimal_medium_experimentSudarsanam00 0.14 0.716 105MCM1_Alpha elp3D Durant06 0.14 0.7165 78OAF1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 0.14 0.7169 43FKH1_YPD Drco1 Keogh05 0.14 0.7174 134DAL82_SM taf1-ts2_25C Huisinga04 0.14 0.7176 53STP1_SM sas3D_taf1-ts2Durant06 0.14 0.7181 61YAP6_H2O2Hi Drpd3 Keogh05 -0.14 0.7181 68DAL82_RAPA SWC6_(VPS71)Krogan04 -0.14 0.7184 44MGA1_YPD rsc30_null Angus-Hill_01 0.14 0.7184 59YAP1_YPD WT_Null_L Chitikila_02 -0.14 0.7185 66RCS1_H2O2Hi DT_V161E Chitikila_02 -0.14 0.7185 47STP1_SM hat2_vs._YPH250Rosaleny05 -0.14 0.7186 66CBF1_SM ubp10 Orlandi04 0.14 0.7189 193ACE2_YPD WT_TAF1_GCN5Huisinga04 -0.14 0.7189 78MGA1_YPD DT_V71R Chitikila_02 -0.14 0.7193 57STE12_BUT14 Ddep1 Keogh05 -0.14 0.7194 120SKN7_YPD WT_TAF1_GCN5Huisinga04 0.14 0.72 67SUM1_YPD 0.1%_MMS Attikum04 -0.14 0.72 30ACE2_YPD RAD6_haploid Hughes00 0.14 0.7206 80RTG3_RAPA gcn5D Durant06 0.14 0.7212 45SKN7_H2O2Loset1 Boa03 0.14 0.7212 183GLN3_RAPA Hda1_del Bernstein02 0.14 0.7215 67GCR2_SM ISW1 Hughes00 0.14 0.7217 54PHD1_YPD taf1-ts2_25C Huisinga04 -0.14 0.7218 63

RLM1_YPD arp8 Attikum04 0.14 0.7218 39RPN4_H2O2LoISW1 Hughes00 -0.14 0.722 99HAP1_YPD SIR2 Hughes00 -0.14 0.7223 139OAF1_YPD elp3D Durant06 -0.14 0.7226 49DAL82_RAPA rpd3_del Sabet04 -0.14 0.7228 53MBP1_H2O2Hihpa2D_taf1-ts2Durant06 -0.14 0.7228 101RTG3_RAPA ARP4 Mnaimneh_04 0.14 0.7234 52PHD1_YPD WT Durant06 0.13 0.7246 66REB1_YPD ubp10 Orlandi04 -0.13 0.7246 103SKN7_H2O2LoZDS1 Hughes00 -0.13 0.7248 182REB1_H2O2Hi DT_V161R_L Chitikila_02 0.13 0.725 56RCS1_H2O2Hi _SWC2_(VPS72)Krogan04 -0.13 0.7251 49SKN7_H2O2HiSIR3 Hughes00 -0.13 0.7252 96STE12_Alpha elp3D_taf1-ts2Durant06 -0.13 0.7252 82GCN4_RAPA SSN6_haploid Hughes00 -0.13 0.7253 159STE12_BUT90 H4_2-26 Sabet04 -0.13 0.7254 74MBP1_H2O2Hiubp10sir4 Orlandi04 0.13 0.7255 98AFT2_H2O2Lo sas3D Durant06 0.13 0.7255 80DAL82_RAPA SGF11 Ingvarsdottir05 -0.13 0.7256 45GLN3_RAPA EAF5 Krogan04 0.13 0.7256 60REB1_H2O2Hi ino80 Attikum04 -0.13 0.7256 50AFT2_H2O2Lo gcn5D_taf1-ts2Durant06 0.13 0.7259 91UME6_YPD EAF7 Krogan04 -0.13 0.7266 125DAL81_RAPA 0.1%_MMS Attikum04 0.13 0.7268 75ACE2_YPD WT Durant06 -0.13 0.7268 76STE12_BUT14 WT Durant06 -0.13 0.7272 122OAF1_YPD Drxt2 Keogh05 -0.13 0.7274 53MCM1_Alpha WT_N69R Chitikila_02 0.13 0.7275 95REB1_H2O2Hi spt10_del Xu05 -0.13 0.7277 57YAP7_H2O2Lo hos3_del Bernstein_00_affydeletions0.13 0.7277 143CIN5_YPD _SWC2_(VPS72)Krogan04 0.13 0.7278 137DAL82_SM hht2_K4G Martin04 0.13 0.7278 41YAP7_H2O2Lo DT_N69S Chitikila_02 -0.13 0.728 140ACE2_YPD isw2_c.i. Fazzio01 -0.13 0.7281 74MCM1_YPD htz1_sir2 Meneghini03 -0.13 0.7282 77RTG3_RAPA SGF11 Ingvarsdottir05 0.13 0.7284 38AFT2_H2O2Hi hpa2D_taf1-ts2Durant06 0.13 0.7284 49YAP7_H2O2Lo hmr Meneghini03 0.13 0.7284 142UME6_YPD hht2_K914182327GMartin04 0.13 0.7286 90GCR2_SM rsc30_null Angus-Hill_01 -0.13 0.7289 51UME6_YPD spt3 Huisinga04 -0.13 0.7291 121RCS1_H2O2LoARP4 Mnaimneh_04 -0.13 0.7293 259GCR2_SM taf1-ts2_spt3_E240KHuisinga04 -0.13 0.7296 44SUM1_YPD hht2_K4914182327GMartin04 0.13 0.73 27GCN4_SM hat2_vs._hat1Rosaleny05 0.13 0.7302 183ASH1_BUT14 elp3D Durant06 0.13 0.7302 38DAL81_RAPA ume6 Fazzio01 -0.13 0.7303 90MGA1_YPD YAF9 Krogan04 -0.13 0.7306 62PUT3_H2O2Lo ume6 Fazzio01 0.13 0.7307 86RPN4_H2O2LoPCH1 Hughes00 -0.13 0.7307 98STE12_BUT14 hmr Meneghini03 -0.13 0.7307 125OAF1_YPD taf1-ts2_spt3_E240KHuisinga04 -0.13 0.7309 58OAF1_YPD Set1_del Bernstein02 -0.13 0.7316 59

SKN7_YPD hat2_vs._YPH250Rosaleny05 0.13 0.7319 61GCR2_SM gcn5_KQL Huisinga04 0.13 0.7319 43MCM1_YPD isw2_ume6 Fazzio01 0.13 0.7319 73FKH1_YPD IES6 Hughes00 -0.13 0.7321 141STE12_YPD hos3_del Bernstein_00_affydeletions0.13 0.7324 49SWI6_YPD SIR3 Hughes00 0.13 0.7327 152HAP1_YPD ZDS1 Hughes00 0.13 0.7328 139SUM1_YPD ISW2 Hughes00 -0.13 0.733 59SUM1_YPD WT_TAF1_GCN5Huisinga04 -0.13 0.7332 55MSN4_H2O2Hispt10 Eriksson05 -0.13 0.7332 70FKH1_YPD hat1D Durant06 0.13 0.7332 105AFT2_H2O2Hi rpd3_del Sabet04 0.13 0.7335 57CIN5_H2O2Hi hpa2D Durant06 -0.13 0.7335 54GLN3_RAPA spt10_del Xu05 0.13 0.7338 67RTG3_RAPA swr1 Meneghini03 0.13 0.7339 42HSF1_H2O2Hi isw2_sin3_vs._sin3Fazzio01 -0.13 0.7339 119NRG1_H2O2HiDume1 Keogh05 -0.13 0.7339 113YAP6_H2O2Hi WT_V161E Chitikila_02 -0.13 0.7341 72DAL82_RAPA HIR2 Hughes00 0.13 0.7343 55DAL81_RAPA htz1 Meneghini03 -0.13 0.7345 91SWI5_YPD swi1_rich_medium_experimentSudarsanam00 -0.13 0.7346 101SKN7_YPD arp8 Attikum04 -0.13 0.735 45PHO4_YPD WT_N69R Chitikila_02 0.13 0.7351 67YAP1_YPD DT_V161R_K Chitikila_02 0.13 0.7352 70AFT2_H2O2Lo WT_V161R_L Chitikila_02 0.13 0.7352 94CBF1_SM taf1-ts2_spt3 Huisinga04 -0.13 0.7353 263CIN5_H2O2Lo YAF9 Krogan04 -0.13 0.7353 119FKH2_YPD ino80_del Mizuguch04 0.13 0.7356 121YAP1_YPD sin3_del Bernstein_00_affydeletions0.13 0.7359 68PHO4_YPD Drpd3 Keogh05 -0.13 0.7363 66AFT2_H2O2Hi HTZ1 Krogan04 0.13 0.7363 58CIN5_H2O2Hi WT_V161E Chitikila_02 -0.13 0.737 76STP1_SM taf1-ts2_SPT3 Huisinga04 0.13 0.7374 64HAP1_YPD H3_1-28 Sabet04 0.13 0.7374 137RTG3_RAPA hat2_vs._hat1Rosaleny05 0.13 0.7375 51STP1_SM gcn5 Huisinga04 0.13 0.7376 63REB1_YPD hpa2D_taf1-ts2Durant06 -0.13 0.7377 114CIN5_H2O2Hi rpd3_H3dN_v_H3dNSabet04 -0.13 0.738 74SWI5_YPD hht2_K27G Martin04 0.13 0.7382 84DAL82_SM DT_V161R_L Chitikila_02 0.13 0.7384 53RCS1_H2O2Loisw2 Fazzio01 0.13 0.7387 253SKN7_YPD isw2_sin3_vs._sin3Fazzio01 -0.13 0.7389 63MCM1_Alpha gcn5_KQL Huisinga04 0.13 0.7391 92FKH1_YPD ubp10sir4 Orlandi04 -0.13 0.7394 108ACE2_YPD HAT2 Hughes00 -0.13 0.7394 79STE12_BUT90 SIR1 Hughes00 0.13 0.7396 78STE12_BUT90 DM_vs._YPH250Rosaleny05 0.13 0.7399 71UME6_YPD hat2_vs._YPH250Rosaleny05 0.13 0.74 124YAP7_H2O2Lo SIN3 Hughes00 0.13 0.7404 151SUM1_YPD snf2_rich_medium_experimentSudarsanam00 -0.13 0.7405 58XBP1_H2O2Lo WT_TAF1_GCN5Huisinga04 -0.13 0.7405 68RCS1_H2O2Hi hpa2D_taf1-ts2Durant06 0.13 0.7412 37MCM1_Alpha hmr Meneghini03 0.13 0.7412 105

STP1_SM EAF7 Krogan04 0.12 0.7415 61STE12_BUT90 MOT1-42 Dasgupta02 -0.12 0.7415 77ROX1_YPD sir4 Orlandi04 -0.12 0.7417 32SOK2_BUT14 WT_TAF1_SPT3Huisinga04 0.12 0.7417 69REB1_H2O2Hi elp3D Durant06 -0.12 0.7418 46DIG1_BUT14 isw2_ume6 Fazzio01 -0.12 0.7419 63GLN3_RAPA swr1_del Mizuguch04 0.12 0.742 68STP1_SM IOC4 Hughes00 0.12 0.7422 66OAF1_YPD snf2_minimal_medium_experimentSudarsanam00 -0.12 0.7422 59STE12_BUT90 WT_WT Chitikila_02 -0.12 0.7423 71RTG3_RAPA Drxt1 Keogh05 0.12 0.7426 52RCS1_H2O2Hi rsc30_null Angus-Hill_01 -0.12 0.7426 50STE12_BUT14 SIR4 Hughes00 0.12 0.7426 128SKN7_YPD isw2_c.i._rpd3_c.i.Fazzio01 -0.12 0.7428 63MBP1_YPD hos3_del Bernstein_00_affydeletions-0.12 0.7428 123DAL82_SM H4KQ Sabet04 0.12 0.743 50RTG3_RAPA MED2_haploid Hughes00 -0.12 0.743 51SKN7_H2O2HiHAT2 Hughes00 0.12 0.743 93MCM1_YPD sin3_del Bernstein_00_affydeletions-0.12 0.7433 71SUM1_YPD ubp10 Orlandi04 0.12 0.7436 20MSN4_RAPA ISW1_ISW2 Hughes00 -0.12 0.7436 53UME6_YPD Dume1 Keogh05 0.12 0.7437 124PHD1_YPD hos3_del Bernstein_00_affydeletions-0.12 0.7438 58AFT2_H2O2Lo hht2_K4G Martin04 -0.12 0.7438 67YAP7_H2O2Hi ume6 Fazzio01 0.12 0.7444 137DIG1_Alpha Hda1_del Bernstein02 -0.12 0.7445 59TYE7_YPD isw2_rpd3 Fazzio01 0.12 0.7446 54MBP1_H2O2LoDume1 Keogh05 0.12 0.7446 52MSN4_H2O2HiSWD2 Mnaimneh_04 0.12 0.7453 70GCN4_SM BUR6 Geisberg_01 -0.12 0.7455 179DIG1_BUT14 sin3 Fazzio01 -0.12 0.7455 63MSN2_H2O2HiEAF7 Krogan04 0.12 0.7458 71REB1_H2O2Hi hat1_vs.YPH250Rosaleny05 -0.12 0.7458 54AFT2_H2O2Lo WT_V161R_K Chitikila_02 0.12 0.7459 92OAF1_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.12 0.7469 56MCM1_YPD delta_ssd1 Kaeberlein04 0.12 0.747 77GCN4_RAPA spt10_del Xu05 -0.12 0.7471 159SWI5_YPD hat2_vs._YPH250Rosaleny05 0.12 0.7477 91PHO4_YPD PCH1 Hughes00 0.12 0.7481 70RTG3_RAPA DT_WT Chitikila_02 -0.12 0.7481 50GLN3_RAPA elp3D Durant06 0.12 0.7483 52DIG1_BUT14 hht2_K914182327GMartin04 -0.12 0.7483 53STP1_SM HAT2 Hughes00 -0.12 0.7485 67GLN3_RAPA hat2_vs._hat1Rosaleny05 -0.12 0.7485 63UME6_H2O2HiWT_V71E Chitikila_02 0.12 0.7488 78ROX1_YPD MOT1-42 Dasgupta02 0.12 0.7489 67SWI4_YPD Drxt2 Keogh05 -0.12 0.7489 150SUM1_YPD hat1_vs.YPH250Rosaleny05 -0.12 0.749 51MSN4_RAPA snf2_minimal_medium_experimentSudarsanam00 -0.12 0.7492 54MCM1_YPD rpd3_del Sabet04 -0.12 0.7493 73PUT3_H2O2Lo Dpho23 Keogh05 0.12 0.7494 88FKH2_YPD ume6 Fazzio01 -0.12 0.7494 119MCM1_YPD hht2_K49141823GMartin04 0.12 0.7496 60

YAP6_H2O2Hi IOC4 Hughes00 -0.12 0.7498 78UME6_H2O2Hihos3_del Bernstein_00_affydeletions-0.12 0.7501 96FKH2_YPD WT_Null_L Chitikila_02 0.12 0.7502 114MCM1_YPD HIR2 Hughes00 0.12 0.7502 77DAL82_RAPA HTZ1 Krogan04 -0.12 0.7504 51DIG1_BUT14 set1 Boa03 0.12 0.7506 62PHD1_YPD EPL1 Mnaimneh_04 0.12 0.7507 67ROX1_YPD SPT8 Ingvarsdottir05 -0.12 0.7509 61ABF1_YPD htz1_sir2 Meneghini03 -0.12 0.7511 261STP1_SM WT_V161E Chitikila_02 -0.12 0.7511 62SUT1_YPD IOC4 Hughes00 -0.12 0.7512 69MCM1_YPD hht2_K914182327GMartin04 -0.12 0.7513 59RTG3_RAPA swr1_del Mizuguch04 0.12 0.7514 52REB1_YPD WT_V161R_L Chitikila_02 0.12 0.7515 133RCS1_H2O2Hi Dpho23 Keogh05 0.12 0.7517 52DIG1_Alpha WT_TAF1_SPT3Huisinga04 -0.12 0.7518 55STE12_BUT90 WT Durant06 -0.12 0.7518 71DAL81_RAPA sap30_del Bernstein_00_affydeletions-0.12 0.7521 91MBP1_H2O2LoISW1 Hughes00 0.12 0.7521 58RCS1_H2O2Lo_SWC2_(VPS72)Krogan04 0.12 0.7522 231GCR2_SM ZDS1 Hughes00 0.12 0.7524 54OAF1_YPD HDA1 Hughes00 -0.12 0.7528 58CBF1_SM HAT2 Hughes00 -0.12 0.7533 278GCN4_SM DT_V71E Chitikila_02 0.12 0.7538 183MCM1_Alpha sas3D Durant06 0.12 0.754 78NDD1_YPD SWD2 Mnaimneh_04 0.12 0.754 85RCS1_H2O2Hi PCH1 Hughes00 -0.12 0.7541 51SKN7_H2O2Hi set1 Boa03 0.12 0.7542 97MCM1_Alpha isw2_ume6 Fazzio01 -0.12 0.7542 104RLM1_YPD hat1D Durant06 0.12 0.7544 44STP1_SM UBP8 Ingvarsdottir05 -0.12 0.7547 61TYE7_YPD hat2_vs._hat1Rosaleny05 0.12 0.7553 53DAL82_SM sas3D Durant06 -0.12 0.7555 47RCS1_H2O2LoEPL1 Mnaimneh_04 0.12 0.7564 259SWI4_YPD PCH1 Hughes00 -0.12 0.7571 155DAL82_RAPA WT_WT Chitikila_02 0.12 0.7571 54MSN2_H2O2Hiume6 Fazzio01 -0.12 0.7571 75FKH1_YPD hat1_vs.YPH250Rosaleny05 0.12 0.7571 136DIG1_BUT14 SSN6_haploid Hughes00 0.12 0.7572 61YAP1_YPD WT Durant06 0.12 0.7577 64STP1_SM ARD1 Hughes00 0.12 0.7577 66DIG1_Alpha isw2_sin3_vs._sin3Fazzio01 -0.12 0.7577 59STP1_SM DT_V161R_K Chitikila_02 -0.12 0.7579 65ACE2_YPD hmr Meneghini03 -0.12 0.758 80MSN2_H2O2HiDume1 Keogh05 0.12 0.7581 73RTG3_RAPA Drxt2 Keogh05 0.12 0.7582 49FKH1_YPD hpa2D Durant06 0.12 0.7582 111FKH1_YPD WT_N69R Chitikila_02 -0.12 0.7582 127REB1_H2O2Hi Drxt2 Keogh05 0.11 0.7587 56MBP1_YPD H3_1-28 Sabet04 -0.11 0.759 126SWI6_YPD IOC4 Hughes00 -0.11 0.7593 151MBP1_H2O2Lohht2_K27G Martin04 0.11 0.7593 44OAF1_YPD SIR3 Hughes00 0.11 0.7593 59

SWI4_YPD sir2 Meneghini03 -0.11 0.7595 154STE12_BUT14 hht2_K49141823GMartin04 -0.11 0.7595 110RCS1_H2O2LoWT_N69S Chitikila_02 0.11 0.7597 226MCM1_YPD set1 Boa03 0.11 0.7597 77YAP7_H2O2Hi hpa2D Durant06 0.11 0.7598 115MBP1_YPD ISW2 Hughes00 -0.11 0.7601 129OAF1_YPD swi1_minimal_medium_experimentSudarsanam00 -0.11 0.7602 59TYE7_YPD ISW1 Hughes00 -0.11 0.7603 56ACE2_YPD rpd3 Fazzio01 -0.11 0.7605 74HAP1_YPD SIR4 Hughes00 0.11 0.7605 140AFT2_H2O2Lo hat1D_taf1-ts2Durant06 0.11 0.7608 84PHO4_YPD arp8 Attikum04 -0.11 0.7609 58RCS1_H2O2Hi WT_V161R_K Chitikila_02 0.11 0.761 47REB1_H2O2Hi isw2 Fazzio01 0.11 0.761 57TYE7_YPD Hda1_del Bernstein02 0.11 0.7612 54YAP6_H2O2Lo IOC4 Hughes00 0.11 0.7612 58ASH1_BUT14 ISW2 Hughes00 -0.11 0.7615 50NDD1_YPD sas3D Durant06 0.11 0.7618 74CIN5_H2O2Hi isw2_sin3_vs._sin3Fazzio01 -0.11 0.7621 79SKN7_YPD isw2_rpd3 Fazzio01 0.11 0.7622 62SUM1_YPD TUP1_haploid Hughes00 0.11 0.7622 58RPN4_H2O2LoDM_vs._YPH250Rosaleny05 0.11 0.7625 93SWI6_YPD Hda1_del Bernstein02 0.11 0.763 151RCS1_H2O2Lohpa2D_taf1-ts2Durant06 0.11 0.763 207RTG3_RAPA WT_N69S Chitikila_02 -0.11 0.7631 50MCM1_YPD ZDS1 Hughes00 -0.11 0.7633 75RCS1_H2O2LoWT_V161R_L Chitikila_02 0.11 0.7634 242YAP1_YPD WT_N69S Chitikila_02 -0.11 0.7641 65UME6_H2O2HiWT Durant06 -0.11 0.7642 97FKH1_YPD ARP4 Mnaimneh_04 -0.11 0.7642 142DAL81_RAPA DT_N69S Chitikila_02 0.11 0.7644 88TYE7_YPD sin3 Fazzio01 -0.11 0.7647 54GCR2_SM htz1_hmr Meneghini03 -0.11 0.7647 52RCS1_H2O2Hi WT_Null_K Chitikila_02 -0.11 0.765 49YAP6_H2O2Hi hmr Meneghini03 0.11 0.765 77TYE7_YPD hht2_K4G Martin04 -0.11 0.7651 51SUM1_YPD hda1_del Bernstein_00_affydeletions-0.11 0.7655 44MBP1_H2O2LoDT_V71R Chitikila_02 -0.11 0.7657 55STP1_SM sin3_del Bernstein_00_affydeletions0.11 0.7658 64ASH1_BUT14 Dpho23 Keogh05 -0.11 0.7658 48SKN7_H2O2HiDeaf3 Keogh05 -0.11 0.7662 89ACE2_YPD WT_Null_K Chitikila_02 -0.11 0.7666 78YAP6_YPD Dume1 Keogh05 -0.11 0.7669 84STE12_BUT90 ino80_del Mizuguch04 -0.11 0.7669 78YAP6_H2O2Hi SSD1-V Kaeberlein04 0.11 0.7672 79MSN4_RAPA hat1_vs.YPH250Rosaleny05 -0.11 0.7673 53REB1_H2O2Hi hda1_del Bernstein_00_affydeletions0.11 0.7673 57SWI6_YPD sin3_del Bernstein_00_affydeletions0.11 0.7675 143TYE7_YPD taf1-ts2_spt3_E240KHuisinga04 -0.11 0.7675 46SUM1_YPD SIR4 Hughes00 -0.11 0.7678 59MCM1_Alpha rpd3_c.i. Fazzio01 0.11 0.7678 104DAL82_RAPA DM_vs._YPH250Rosaleny05 0.11 0.7682 51MBP1_YPD HIR2 Hughes00 -0.11 0.7685 128

DAL82_RAPA SWR1 Krogan04 0.11 0.7686 54DAL82_RAPA DT_N69R Chitikila_02 0.11 0.7686 53OAF1_YPD TUP1_haploid Hughes00 0.11 0.7686 59RCS1_H2O2LoSIR2 Hughes00 -0.11 0.7689 255CIN5_YPD Drxt2 Keogh05 -0.11 0.7693 141YAP6_YPD hmr Meneghini03 0.11 0.7696 89OAF1_YPD YAF9 Krogan04 0.11 0.7697 53MGA1_YPD HTZ1 Krogan04 0.11 0.77 59REB1_YPD DT_N69R Chitikila_02 0.11 0.7706 132AFT2_H2O2Lo ume6_del Bernstein_00_affydeletions-0.11 0.7709 87CBF1_SM H4_2-26 Sabet04 -0.11 0.7711 271RPN4_H2O2LoDrco1 Keogh05 -0.11 0.7711 98FKH2_YPD sin3_del Bernstein_00_affydeletions0.11 0.7713 116PHD1_BUT90 Dsin3 Keogh05 0.11 0.7714 90MCM1_YPD Dsds3 Keogh05 -0.11 0.7715 72REB1_YPD SSD1-V Kaeberlein04 0.11 0.7717 141MGA1_YPD sas3D Durant06 -0.11 0.772 48ASH1_BUT14 Drxt2 Keogh05 -0.11 0.7721 49DAL82_RAPA gcn5_KQL Huisinga04 -0.11 0.7722 49DAL82_SM SWC6_(VPS71)Krogan04 0.11 0.7723 45CBF1_SM taf1-ts2_spt3_E240KHuisinga04 0.11 0.7725 248AFT2_H2O2Hi VID21 Krogan04 -0.11 0.7726 58UME6_YPD EAF5 Krogan04 0.11 0.7728 117MGA1_YPD Hda1_del Bernstein02 -0.11 0.7729 61DIG1_Alpha Deaf3 Keogh05 -0.11 0.7732 53YAP6_YPD YAF9 Krogan04 0.11 0.7733 86NRG1_H2O2Hihmr Meneghini03 0.11 0.7738 122SKN7_YPD swr1_del Mizuguch04 -0.11 0.7741 67DIG1_BUT14 isw2_c.i._rpd3_c.i.Fazzio01 -0.11 0.7744 63RCS1_H2O2Hi hat1_vs.YPH250Rosaleny05 0.11 0.7746 50RCS1_H2O2Hi taf1-ts2_GCN5Huisinga04 0.11 0.7746 48GCN4_RAPA gcn5D Durant06 -0.11 0.7747 148PHO4_YPD rpd3_c.i. Fazzio01 0.11 0.7748 71SUM1_YPD SIR2 Hughes00 0.11 0.7748 59CIN5_H2O2Hi SWD2 Mnaimneh_04 -0.11 0.7753 80MSN2_H2O2HiSIR2 Hughes00 -0.11 0.7758 77SUT1_YPD SGF11 Ingvarsdottir05 0.11 0.7761 56REB1_YPD IOC4 Hughes00 -0.1 0.7764 142MSN4_RAPA gcn5_KQL Huisinga04 -0.1 0.7767 49AFT2_H2O2Lo WT_V161E Chitikila_02 -0.1 0.7769 95AFT2_H2O2Lo htz1_hmr Meneghini03 -0.1 0.7773 95ROX1_YPD spt10_del Xu05 -0.1 0.7778 65AFT2_H2O2Hi elp3D Durant06 -0.1 0.7782 56SKN7_H2O2Hi ISW2 Hughes00 0.1 0.7786 96RTG3_RAPA sin3 Fazzio01 -0.1 0.7787 51RPN4_H2O2LoSIR3 Hughes00 0.1 0.7787 99STP1_SM SPT3 Ingvarsdottir05 -0.1 0.779 58XBP1_H2O2Lo IES6 Hughes00 0.1 0.779 67SUM1_YPD hos3_del Bernstein_00_affydeletions-0.1 0.7791 43AFT2_H2O2Hi SPT8 Ingvarsdottir05 -0.1 0.7796 56STE12_YPD SGF11 Ingvarsdottir05 0.1 0.7797 47STE12_BUT14 Dpho23 Keogh05 0.1 0.7798 127CIN5_H2O2Hi Dsds3 Keogh05 0.1 0.7799 74

AFT2_H2O2Hi taf1-ts2_SPT3 Huisinga04 0.1 0.78 58ACE2_YPD ZDS1 Hughes00 0.1 0.7803 79STE12_YPD hat1_vs.YPH250Rosaleny05 0.1 0.7804 51CIN5_H2O2Hi SIR3 Hughes00 -0.1 0.7805 79RLM1_YPD WT_TAF1_GCN5Huisinga04 0.1 0.7807 53RCS1_H2O2Hi VID21 Krogan04 0.1 0.781 45RLM1_YPD hat2_vs._hat1Rosaleny05 -0.1 0.7813 53RCS1_H2O2Hi DT_N69S Chitikila_02 -0.1 0.7817 48MBP1_YPD hht2_K914182327GMartin04 0.1 0.7819 112PHD1_BUT90 WT_TAF1_GCN5Huisinga04 0.1 0.782 105MCM1_YPD YNG2 Mnaimneh_04 0.1 0.7826 77FKH2_H2O2Hi hos2_del Bernstein_00_affydeletions0.1 0.783 101OAF1_YPD taf1-ts2 Durant06 0.1 0.7837 59TYE7_YPD Dsin3 Keogh05 -0.1 0.7838 50GCN4_SM MOT1-42 Dasgupta02 0.1 0.7839 189CIN5_H2O2Hi taf1-ts2_gcn5 Huisinga04 0.1 0.7841 76DAL82_SM _SWC2_(VPS72)Krogan04 0.1 0.7845 51CIN5_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.1 0.7847 122GCN4_SM gcn5 Huisinga04 0.1 0.7847 181DIG1_Alpha ISW1_ISW2 Hughes00 -0.1 0.7849 60ASH1_BUT14 rpd3_c.i. Fazzio01 0.1 0.7849 49YAP1_YPD HAT2 Hughes00 -0.1 0.785 72SWI6_YPD WT_TAF1_SPT3Huisinga04 0.1 0.7852 150GLN3_RAPA hpa2D Durant06 0.1 0.7854 55AFT2_H2O2Hi isw2_rpd3_vs._rpd3Fazzio01 0.1 0.7854 58GCN4_YPD Set1_del Bernstein02 0.1 0.7859 75PHO4_YPD hht2_K4G Martin04 0.1 0.786 61REB1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 0.1 0.7863 116YAP7_H2O2Lo DT_V71R Chitikila_02 0.1 0.7864 145PHD1_YPD hpa2D_taf1-ts2Durant06 0.1 0.7867 43ABF1_YPD hos3_del Bernstein_00_affydeletions0.1 0.787 254PHO4_YPD SIR2 Hughes00 -0.1 0.7871 70NDD1_YPD taf1-ts2_gcn5_KQLHuisinga04 -0.1 0.7872 68REB1_YPD taf1-ts2_gcn5 Huisinga04 -0.1 0.7874 134UME6_YPD HAT2 Hughes00 -0.1 0.7879 128MSN4_RAPA hpa2D_taf1-ts2Durant06 0.1 0.7882 40REB1_H2O2Hi Dsap30 Keogh05 0.1 0.7887 55YAP7_H2O2Hi DT_N69R Chitikila_02 0.1 0.7892 134PHO4_YPD MED2_haploid Hughes00 0.1 0.7894 71ROX1_YPD ubp10 Orlandi04 0.1 0.7894 37AFT2_H2O2Lo rpd3_H4KQ_v_H4KQSabet04 -0.1 0.7894 92GCR2_SM RSC8 Mnaimneh_04 0.1 0.7899 54RCS1_H2O2Hi DT_WT Chitikila_02 -0.1 0.7899 49FKH2_H2O2Hi ubp10 Orlandi04 -0.1 0.79 73RCS1_H2O2Hi Dsds3 Keogh05 -0.1 0.7901 49NDD1_YPD sir2 Meneghini03 0.1 0.7901 83YAP6_H2O2Hi Deaf3 Keogh05 -0.1 0.7902 72SUM1_YPD ino80 Attikum04 0.1 0.7903 31OAF1_YPD hht2_K4G Martin04 -0.1 0.7903 42REB1_H2O2Hi HTZ1 Krogan04 -0.1 0.7904 55CIN5_H2O2Hi DT_N69R Chitikila_02 0.1 0.7909 76AFT2_H2O2Lo HST3 Hughes00 0.1 0.7909 96REB1_YPD Dsds3 Keogh05 0.1 0.791 129

TYE7_YPD WT_V71R Chitikila_02 -0.1 0.7911 50FKH2_H2O2Hi spt3_E240K Huisinga04 -0.1 0.7913 98YAP6_H2O2Lo WT_Null_L Chitikila_02 -0.1 0.7914 53SUM1_YPD WT_WT Chitikila_02 -0.1 0.7915 51MGA1_YPD swr1 Meneghini03 0.1 0.7917 53YAP6_YPD ZDS1 Hughes00 -0.1 0.7919 90FKH2_H2O2Hi taf1-ts2_SPT3 Huisinga04 0.1 0.7919 99RCS1_H2O2Hi WT Durant06 -0.1 0.792 48MBP1_H2O2LoDsin3 Keogh05 0.1 0.7927 47NRG1_H2O2Hihat1D Durant06 -0.1 0.7928 91RCS1_H2O2Lotaf1-ts2_SPT3 Huisinga04 0.1 0.7929 242TYE7_YPD spt10_del Xu05 -0.1 0.793 55HAP4_YPD HDA1 Hughes00 -0.1 0.793 67DAL82_RAPA DT_V71E Chitikila_02 -0.1 0.7932 53OAF1_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 0.1 0.7936 44MBP1_H2O2Lohat1D Durant06 0.1 0.7939 40RCS1_H2O2Lorpd3_del Sabet04 -0.1 0.7939 253SOK2_BUT14 hat1D Durant06 -0.1 0.7939 49YAP6_H2O2Hi spt10 Eriksson05 -0.1 0.7941 73MCM1_YPD WT_F182V Chitikila_02 -0.1 0.7941 59RIM101_H2O2Lodelta_ssd1 Kaeberlein04 -0.1 0.7942 54STE12_BUT14 ISW1 Hughes00 0.09 0.7944 128UME6_H2O2Hiset1 Boa03 0.09 0.7946 101STE12_YPD HAT2 Hughes00 0.09 0.795 54NDD1_YPD WT_Null_K Chitikila_02 0.09 0.7954 82NDD1_YPD spt3_E240K Huisinga04 0.09 0.7957 78FKH1_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.09 0.7958 139YAP1_YPD hat1D Durant06 0.09 0.796 58NDD1_YPD DT_V161R_K Chitikila_02 -0.09 0.796 83YAP6_H2O2Hi hat2_vs._hat1Rosaleny05 0.09 0.7961 70XBP1_H2O2Lo set1 Boa03 -0.09 0.7961 66FKH2_YPD H4_2-26 Sabet04 0.09 0.7962 118YAP1_YPD hat2_vs._YPH250Rosaleny05 0.09 0.7964 70STE12_BUT14 elp3D_taf1-ts2Durant06 0.09 0.7964 98HSF1_H2O2LoWT_N69S Chitikila_02 0.09 0.7968 93GLN3_RAPA swr1 Meneghini03 -0.09 0.7969 60RTG3_RAPA isw2_sin3_vs._sin3Fazzio01 0.09 0.7969 51YAP1_YPD spt10 Eriksson05 -0.09 0.7972 70PHO4_YPD WT_WT Chitikila_02 0.09 0.7974 71STE12_Alpha DM_vs._YPH250Rosaleny05 -0.09 0.7974 103HAP1_YPD PCH1 Hughes00 0.09 0.7975 137HAP4_YPD taf1-ts2 Durant06 -0.09 0.7975 66OAF1_YPD sas3D_taf1-ts2Durant06 -0.09 0.7978 55STE12_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.09 0.798 41GCN4_SM SWC6_(VPS71)Krogan04 0.09 0.798 170HAP1_YPD rpd3_H3dN_v_H3dNSabet04 0.09 0.7982 136HAP4_YPD DT_WT Chitikila_02 0.09 0.7982 66FKH1_YPD hat1D_taf1-ts2Durant06 0.09 0.7983 118FKH2_H2O2Hi ino80_del Mizuguch04 -0.09 0.7984 106MBP1_H2O2HiSIR1 Hughes00 0.09 0.7984 131DAL82_RAPA DT_V161R_L Chitikila_02 0.09 0.7985 51SKN7_H2O2LoDT_V161R_K Chitikila_02 0.09 0.7987 180MCM1_YPD SSN6_haploid Hughes00 0.09 0.7988 76

GCN4_RAPA ino80 Attikum04 -0.09 0.8 134RIM101_H2O2Lohht2_K4G Martin04 0.09 0.8003 31GLN3_RAPA SGF11 Ingvarsdottir05 0.09 0.8004 54YAP6_H2O2Lo SWC6_(VPS71)Krogan04 0.09 0.8004 53RTG3_RAPA ino80_del Mizuguch04 -0.09 0.8007 52DIG1_Alpha hat2_vs._hat1Rosaleny05 -0.09 0.8007 55DAL82_RAPA rsc3-2 Angus-Hill_01 0.09 0.8014 54MSN4_H2O2Hihmr Meneghini03 -0.09 0.8014 69MCM1_YPD swi1_minimal_medium_experimentSudarsanam00 -0.09 0.802 77DAL82_RAPA EAF5 Krogan04 0.09 0.8021 50CIN5_H2O2Lo hat2_vs._YPH250Rosaleny05 -0.09 0.8021 117STP1_SM Dsin3 Keogh05 -0.09 0.8022 61MCM1_Alpha isw2_sin3_vs._sin3Fazzio01 0.09 0.8023 104PHO4_YPD DT_V71R Chitikila_02 0.09 0.8024 67DIG1_Alpha hos3_del Bernstein_00_affydeletions-0.09 0.8025 53STE12_BUT14 HIR2 Hughes00 0.09 0.8028 125RCS1_H2O2Loset1 Boa03 -0.09 0.8038 250RPN4_H2O2Lohat1_vs.YPH250Rosaleny05 0.09 0.8039 93SWI4_YPD ubp10 Orlandi04 0.09 0.804 102RCS1_H2O2Hi hat1D_taf1-ts2Durant06 -0.09 0.8043 45UME6_YPD 0.1%_MMS Attikum04 0.09 0.8046 87MCM1_YPD rsc30_null Angus-Hill_01 -0.09 0.8046 74MSN4_RAPA swi1_minimal_medium_experimentSudarsanam00 0.09 0.8047 54CIN5_H2O2Lo ZDS1 Hughes00 -0.09 0.8047 124MBP1_H2O2Hi sir4 Orlandi04 -0.09 0.8049 91DAL82_RAPA SIR1 Hughes00 0.09 0.805 56RCS1_H2O2Hi hat2_vs._hat1Rosaleny05 0.09 0.8051 51DIG1_BUT14 isw2_sin3 Fazzio01 -0.09 0.8051 63MBP1_H2O2LoZDS1 Hughes00 -0.09 0.8054 57YAP1_YPD DT_V71E Chitikila_02 0.09 0.8056 69MCM1_Alpha taf1-ts2_spt3 Huisinga04 0.09 0.8058 101ROX1_YPD SIN3 Hughes00 0.09 0.8061 66STE12_Alpha hat1D_taf1-ts2Durant06 -0.09 0.8061 92STP1_SM SGF11 Ingvarsdottir05 -0.09 0.8062 58RLM1_YPD htz1_hmr Meneghini03 0.09 0.8064 51DAL82_RAPA WT_V71R Chitikila_02 -0.09 0.8065 51DIG1_BUT14 Deaf3 Keogh05 -0.09 0.8068 62MBP1_YPD MOT1-14 Dasgupta02 -0.09 0.8072 130DIG1_Alpha taf1-ts2_spt3_E240KHuisinga04 0.09 0.8073 53MCM1_Alpha IES6 Hughes00 -0.09 0.8074 106SWI6_YPD WT_Null_K Chitikila_02 -0.09 0.8076 146REB1_H2O2Hi hmr Meneghini03 0.09 0.8076 56SWI4_YPD hht2_K914182327GMartin04 0.09 0.8078 125MSN4_RAPA set1 Boa03 -0.09 0.8079 53CIN5_H2O2Lo Dsap30 Keogh05 -0.09 0.808 118YAP7_H2O2Lo EAF7 Krogan04 0.09 0.808 140HAP1_YPD arp8 Attikum04 0.09 0.8081 111XBP1_H2O2Lo spt10_del Xu05 -0.09 0.8087 67SWI6_YPD ISW2 Hughes00 -0.09 0.8088 153YAP7_H2O2Lo elp3D Durant06 0.09 0.8092 126PHD1_YPD Drpd3 Keogh05 0.09 0.8094 60CIN5_YPD WT_Null_L Chitikila_02 0.09 0.8095 139MCM1_YPD DT_V161R_K Chitikila_02 0.09 0.8095 74

MBP1_H2O2Lospt10_del Xu05 -0.09 0.8097 55ASH1_BUT14 arp8 Attikum04 0.09 0.8097 32MSN4_RAPA isw2_c.i._rpd3_c.i.Fazzio01 -0.09 0.8099 53SKN7_YPD isw2_ume6 Fazzio01 -0.09 0.8101 63MBP1_H2O2HiDrxt2 Keogh05 0.09 0.8104 125STE12_BUT14 WT_V161E Chitikila_02 -0.09 0.8111 120HSF1_H2O2Lohht2_K4914182327GMartin04 0.09 0.8114 83REB1_H2O2Hi IES6 Hughes00 0.09 0.8115 58GCN4_YPD Hda1_del Bernstein02 0.09 0.8116 74YAP7_H2O2Hi swr1_del Mizuguch04 0.09 0.8119 141YAP6_YPD IOC4 Hughes00 0.09 0.8122 91RCS1_H2O2Hi ume6_del Bernstein_00_affydeletions-0.09 0.8122 47MBP1_H2O2LoIOC4 Hughes00 0.09 0.8122 57GCN4_RAPA BUR6 Geisberg_01 0.09 0.8125 150RCS1_H2O2LoSWR1 Krogan04 0.09 0.8128 233ROX1_YPD BUR6 Geisberg_01 -0.08 0.8129 61HAP4_YPD hos3_del Bernstein_00_affydeletions0.08 0.813 57ROX1_YPD Drco1 Keogh05 0.08 0.8131 62RCS1_H2O2LoUBP8 Ingvarsdottir05 0.08 0.8131 233TYE7_YPD VID21 Krogan04 0.08 0.8132 54RTG3_RAPA Hda1_del Bernstein02 -0.08 0.8133 52MCM1_YPD spt10 Eriksson05 -0.08 0.8134 74GCR2_SM ubp10 Orlandi04 -0.08 0.8136 41MSN4_RAPA HTZ1 Krogan04 -0.08 0.8136 50ASH1_BUT14 hat1D Durant06 -0.08 0.8136 34PHO4_YPD htz1_hmr Meneghini03 0.08 0.8137 71HAP1_YPD MOT1-42 Dasgupta02 -0.08 0.8137 141MBP1_H2O2Loarp8 Attikum04 0.08 0.8139 46NDD1_YPD MOT1-14 Dasgupta02 0.08 0.8139 85DAL82_RAPA Deaf3 Keogh05 -0.08 0.8144 52CBF1_SM WT Durant06 0.08 0.8147 258TYE7_YPD H3_1-28 Sabet04 -0.08 0.8148 55YAP7_H2O2Lo hht2K9131823GMartin04 0.08 0.8152 127YAP7_H2O2Hi EAF7 Krogan04 0.08 0.8153 133MCM1_YPD taf1-ts2_gcn5_KQLHuisinga04 0.08 0.8153 68REB1_YPD isw2_sin3_vs._sin3Fazzio01 -0.08 0.8156 141UME6_YPD IES6 Hughes00 -0.08 0.8156 129NRG1_YPD YAF9 Krogan04 0.08 0.8156 62GCN4_RAPA EAF7 Krogan04 0.08 0.8157 148AFT2_H2O2Lo hht2K9131823GMartin04 0.08 0.8157 68DIG1_BUT14 IOC4 Hughes00 -0.08 0.8158 63NDD1_YPD Dsin3 Keogh05 0.08 0.8158 69DAL82_RAPA snf2_rich_medium_experimentSudarsanam00 0.08 0.8159 56STP1_SM gcn5D Durant06 -0.08 0.8162 53GCR2_SM WT Durant06 -0.08 0.8166 50MBP1_YPD spt10 Eriksson05 -0.08 0.8167 130MSN4_RAPA ume6 Fazzio01 -0.08 0.8169 53SKN7_H2O2LoWT_WT Chitikila_02 -0.08 0.8169 179STP1_SM hpa2D_taf1-ts2Durant06 0.08 0.8173 49GLN3_RAPA hht2_K4914182327GMartin04 0.08 0.8173 51RLM1_YPD WT_V71E Chitikila_02 -0.08 0.8176 49MCM1_YPD WT_V71E Chitikila_02 0.08 0.8177 64OAF1_YPD HST3 Hughes00 0.08 0.8177 57

MSN2_H2O2HiDT_V161R_K Chitikila_02 -0.08 0.8182 78ACE2_YPD elp3D Durant06 0.08 0.8184 65CIN5_H2O2Lo hat2_vs._hat1Rosaleny05 -0.08 0.8185 118RCS1_H2O2Lohmr Meneghini03 -0.08 0.8186 247STE12_YPD WT_V161R_K Chitikila_02 -0.08 0.8191 45CIN5_H2O2Hi Dsap30 Keogh05 -0.08 0.8192 76AFT2_H2O2Hi TUP1_haploid Hughes00 0.08 0.8194 61DAL82_RAPA DT_N69S Chitikila_02 -0.08 0.8198 50STE12_YPD taf1-ts2_spt3_E240KHuisinga04 -0.08 0.82 46YAP7_H2O2Lo IES6 Hughes00 -0.08 0.82 149GCN4_YPD WT_Null_K Chitikila_02 0.08 0.8202 71OAF1_YPD YNG2 Mnaimneh_04 0.08 0.8209 59STE12_Alpha HAT2 Hughes00 -0.08 0.8216 113DIG1_BUT14 taf1-ts2_gcn5_KQLHuisinga04 0.08 0.8216 48TYE7_YPD RSC8 Mnaimneh_04 0.08 0.8217 56YAP6_H2O2Hi TAF2 Mnaimneh_04 -0.08 0.8217 79REB1_H2O2Hi H3_1-28 Sabet04 -0.08 0.8218 57SWI5_YPD hht2_K914182327GMartin04 0.08 0.8219 84YAP7_H2O2Lo swr1_del Mizuguch04 0.08 0.8221 152DAL82_SM DT_N69S Chitikila_02 -0.08 0.8224 49RTG3_RAPA EAF5 Krogan04 0.08 0.8224 48YAP1_YPD DT_N69S Chitikila_02 0.08 0.8227 68DIG1_BUT14 SIN3 Hughes00 0.08 0.8227 63STE12_BUT90 hht2_K4914182327GMartin04 0.08 0.8227 68CIN5_H2O2Lo SIR1 Hughes00 -0.08 0.8228 126CIN5_H2O2Lo VID21 Krogan04 0.08 0.8229 116TYE7_YPD TUP1_haploid Hughes00 -0.08 0.823 55STP1_SM sir4 Orlandi04 -0.08 0.823 45MBP1_H2O2HiHda1_del Bernstein02 0.08 0.8231 131STE12_YPD isw2_rpd3_vs._rpd3Fazzio01 -0.08 0.8232 54NRG1_YPD hat2_vs._hat1Rosaleny05 -0.08 0.8234 65CIN5_H2O2Hi taf1-ts2_spt3 Huisinga04 -0.08 0.8237 75OAF1_YPD esa1-414 Durant06 0.08 0.8237 54REB1_YPD htz1_del Mizuguch04 -0.08 0.824 144AFT2_H2O2Lo Drxt2 Keogh05 0.08 0.824 90YAP6_YPD _SWC2_(VPS72)Krogan04 -0.08 0.8241 85REB1_YPD YNG2 Krogan04 -0.08 0.8242 137CIN5_YPD set1 Boa03 -0.08 0.8242 148STP1_SM VID21 Krogan04 0.08 0.8242 61HAP1_YPD elp3D Durant06 -0.08 0.8247 125SWI5_YPD SIR4 Hughes00 0.08 0.8248 100RCS1_H2O2LoDT_V161R_K Chitikila_02 -0.08 0.8249 245UME6_YPD hht2_K49141823GMartin04 -0.08 0.8251 91STE12_BUT14 EAF5 Krogan04 -0.08 0.8251 118RIM101_H2O2LoSIR1 Hughes00 -0.08 0.8253 53ACE2_YPD hht2_K49141823GMartin04 -0.08 0.8253 64ASH1_BUT14 UBP8 Hughes00 0.08 0.8254 50CIN5_H2O2Hi DT_V71R Chitikila_02 0.08 0.8255 76STE12_Alpha hat1_vs.YPH250Rosaleny05 -0.08 0.826 111MCM1_YPD SPT3 Ingvarsdottir05 -0.08 0.826 67TYE7_YPD hos3_del Bernstein_00_affydeletions0.08 0.8262 54STE12_BUT14 hpa2D_taf1-ts2Durant06 -0.08 0.8263 94TYE7_YPD taf1-ts2 Durant06 0.08 0.8265 53

MBP1_H2O2Lohpa2D Durant06 -0.08 0.8266 48DIG1_BUT14 taf1-ts2_spt3_E240KHuisinga04 0.08 0.8268 57MSN4_RAPA hat1D Durant06 -0.08 0.8269 35RIM101_H2O2LoWT_WT Chitikila_02 0.08 0.8272 50STE12_BUT90 Dsin3 Keogh05 -0.08 0.8273 65FKH2_YPD SWD2 Mnaimneh_04 0.08 0.8274 121RTG3_RAPA YAF9 Krogan04 -0.08 0.8282 49GCN4_RAPA Drco1 Keogh05 -0.08 0.8283 152SKN7_H2O2LoDT_V71R Chitikila_02 0.08 0.8284 177DIG1_BUT14 H3_1-28 Sabet04 -0.08 0.8284 63DAL81_RAPA WT_TAF1_SPT3Huisinga04 -0.08 0.8286 91REB1_YPD htz1_sir2 Meneghini03 -0.08 0.829 138REB1_YPD Drxt2 Keogh05 0.08 0.829 135YAP1_YPD gcn5_KQL Huisinga04 -0.08 0.8292 58CIN5_H2O2Lo WT_Null_K Chitikila_02 -0.08 0.8298 124RCS1_H2O2Hi WT_F182V Chitikila_02 0.08 0.8301 39MSN4_RAPA isw2_rpd3 Fazzio01 0.08 0.8306 53YAP7_H2O2Lo gcn5D Durant06 -0.08 0.8307 127YAP7_H2O2Hi spt3 Huisinga04 -0.08 0.8308 136DIG1_BUT14 Drco1 Keogh05 -0.08 0.8309 61PHO4_YPD HTZ1 Krogan04 0.08 0.8312 69RTG3_RAPA rpd3_c.i. Fazzio01 0.08 0.8314 51MBP1_YPD hat1D Durant06 0.07 0.8321 96RCS1_H2O2Hi WT_Null_L Chitikila_02 0.07 0.8323 50GCN4_YPD H3_1-28 Sabet04 -0.07 0.8327 75PUT3_H2O2Lo ZDS1 Hughes00 -0.07 0.8338 86RCS1_H2O2LoWT_V161R_K Chitikila_02 0.07 0.8339 226ACE2_YPD hat2_vs._YPH250Rosaleny05 -0.07 0.834 75HSF1_H2O2LoDume1 Keogh05 -0.07 0.8342 90AFT2_H2O2Hi taf1-ts2_GCN5Huisinga04 0.07 0.8344 58DIG1_Alpha H4KQ Sabet04 -0.07 0.8352 56YAP6_YPD delta_ssd1 Kaeberlein04 0.07 0.8353 91STE12_Alpha WT_WT Chitikila_02 0.07 0.8354 105AFT2_H2O2Hi EAF5 Krogan04 0.07 0.8356 56FKH2_H2O2Hi hat2_vs._YPH250Rosaleny05 -0.07 0.8356 100MSN4_RAPA EAF7 Krogan04 0.07 0.836 50RIM101_H2O2Lohat2_vs._hat1Rosaleny05 -0.07 0.8361 49FKH2_YPD arp8 Attikum04 0.07 0.8361 94MCM1_YPD hat2_vs._hat1Rosaleny05 0.07 0.8362 72OAF1_YPD WT_Null_K Chitikila_02 0.07 0.8364 54STP1_SM Drco1 Keogh05 -0.07 0.8365 63REB1_YPD hat2_vs._hat1Rosaleny05 0.07 0.8366 139MBP1_H2O2LoDT_V161E Chitikila_02 -0.07 0.8366 54MCM1_Alpha swi1_rich_medium_experimentSudarsanam00 -0.07 0.8368 106FKH2_YPD DT_N69R Chitikila_02 -0.07 0.8369 110STP1_SM isw2 Fazzio01 0.07 0.8371 67GLN3_RAPA gcn5 Huisinga04 -0.07 0.8371 65RCS1_H2O2Hi WT_V71E Chitikila_02 0.07 0.8372 40FKH1_YPD IOC4 Hughes00 0.07 0.8374 140STE12_Alpha WT_V71E Chitikila_02 0.07 0.8376 93MGA1_YPD ZDS1 Hughes00 -0.07 0.8378 61ACE2_YPD H3_1-28 Sabet04 0.07 0.8379 77YAP7_H2O2Lo DT_N69R Chitikila_02 0.07 0.8381 141

STP1_SM swr1 Meneghini03 0.07 0.8388 57NRG1_H2O2Hihpa2D Durant06 -0.07 0.8389 95UME6_H2O2Hiino80 Attikum04 -0.07 0.8389 70CBF1_SM UBP8 Hughes00 -0.07 0.839 277PHO4_YPD SPT8 Ingvarsdottir05 0.07 0.8391 67RCS1_H2O2Hi Drxt2 Keogh05 0.07 0.8393 48RTG3_RAPA Rpd3_del Bernstein02 -0.07 0.8394 52YAP6_H2O2Lo SIR3 Hughes00 0.07 0.8396 57MCM1_YPD taf1-ts2_spt3_E240KHuisinga04 0.07 0.8396 70SKN7_YPD WT_WT Chitikila_02 -0.07 0.8397 65YAP6_YPD hat2_vs._YPH250Rosaleny05 -0.07 0.8398 86DAL82_SM SIN3 Hughes00 0.07 0.84 54GCR2_SM elp3D Durant06 -0.07 0.8408 50MGA1_YPD YNG2 Mnaimneh_04 -0.07 0.8408 63CIN5_H2O2Lo SIR3 Hughes00 0.07 0.8411 126GCR2_SM RAD6_haploid Hughes00 -0.07 0.8413 54SKN7_YPD 0.1%_MMS Attikum04 -0.07 0.8415 48HAP1_YPD rpd3_del Sabet04 -0.07 0.8415 137RTG3_RAPA H4_2-26 Sabet04 0.07 0.8418 49NDD1_YPD ume6 Fazzio01 -0.07 0.842 80ACE2_YPD gcn5 Huisinga04 0.07 0.8424 77CBF1_SM htz1_hmr Meneghini03 0.07 0.8432 270STP1_SM Drpd3 Keogh05 -0.07 0.8435 57MBP1_H2O2LoDpho23 Keogh05 -0.07 0.8438 57OAF1_YPD SWC6_(VPS71)Krogan04 0.07 0.8438 52DAL82_RAPA IOC4 Hughes00 0.07 0.8439 54YAP6_YPD EAF7 Krogan04 0.07 0.8443 85DIG1_BUT14 hos3_del Bernstein_00_affydeletions-0.07 0.8443 62RTG3_RAPA UBP8 Ingvarsdottir05 -0.07 0.8446 48OAF1_YPD taf1-ts2_gcn5 Huisinga04 -0.07 0.8448 57DAL82_RAPA ARD1 Hughes00 0.07 0.8451 55SKN7_YPD ARD1 Hughes00 -0.07 0.8456 66DIG1_BUT14 MOT1-14 Dasgupta02 -0.07 0.8456 63MBP1_H2O2LoH3_1-28 Sabet04 -0.07 0.8457 56STE12_YPD Hda1_del Bernstein02 0.07 0.8458 51DIG1_Alpha hht2_K49141823GMartin04 -0.07 0.8463 42FKH2_YPD hht2_K4G Martin04 0.07 0.8464 100HSF1_H2O2Hi WT_N69S Chitikila_02 -0.07 0.8467 113MGA1_YPD _SWC2_(VPS72)Krogan04 -0.07 0.8468 60NRG1_H2O2Hiset1 Boa03 -0.07 0.8472 121OAF1_YPD 0.1%_MMS Attikum04 0.07 0.8473 44PHD1_YPD PCH1 Hughes00 -0.07 0.8475 67GCN4_SM hos3_del Bernstein_00_affydeletions-0.07 0.8475 183UME6_H2O2Hiswr1_del Mizuguch04 0.07 0.8475 101SUT1_YPD hos3_del Bernstein_00_affydeletions0.07 0.8476 61REB1_H2O2Hi Drco1 Keogh05 0.07 0.8477 57PHO4_YPD RAD6_haploid Hughes00 -0.07 0.8484 70MCM1_YPD TUP1_haploid Hughes00 -0.07 0.8484 77SKN7_H2O2HiDT_N69R Chitikila_02 -0.07 0.8485 89AFT2_H2O2Lo SIR2 Hughes00 -0.07 0.8488 98RCS1_H2O2LoWT_Null_K Chitikila_02 0.07 0.849 241SKN7_H2O2LoDume1 Keogh05 -0.07 0.849 173NDD1_YPD SGF11 Ingvarsdottir05 0.07 0.8493 67

SUT1_YPD EAF5 Krogan04 0.07 0.8496 61YAP6_H2O2Lo DT_V71R Chitikila_02 -0.07 0.8497 54NRG1_H2O2Hidelta_ssd1 Kaeberlein04 0.07 0.8498 124ROX1_YPD YAF9 Krogan04 -0.07 0.8499 61SUT1_YPD spt10 Eriksson05 -0.07 0.8502 66OAF1_YPD ubp10 Orlandi04 -0.07 0.8503 32YAP1_YPD snf2_rich_medium_experimentSudarsanam00 -0.07 0.8508 71RPN4_H2O2LoHTZ1 Krogan04 -0.07 0.8508 96MGA1_YPD ino80_del Mizuguch04 -0.07 0.8509 62MBP1_H2O2LoSSN6_haploid Hughes00 -0.06 0.8514 56FKH2_YPD hmr Meneghini03 -0.06 0.8517 118PHO4_YPD SWC6_(VPS71)Krogan04 -0.06 0.8519 68MSN2_H2O2Hihmr Meneghini03 -0.06 0.8519 77DIG1_Alpha hht2_K27G Martin04 -0.06 0.8519 43RLM1_YPD sap30_del Bernstein_00_affydeletions-0.06 0.852 46STE12_BUT90 isw2_c.i. Fazzio01 0.06 0.852 77FKH2_H2O2Hi spt3 Huisinga04 -0.06 0.8521 100TYE7_YPD Rpd3_del Bernstein02 -0.06 0.8524 54SKN7_YPD swr1 Meneghini03 0.06 0.8525 51MGA1_YPD htz1 Meneghini03 0.06 0.8526 59PHO4_YPD snf2_minimal_medium_experimentSudarsanam00 0.06 0.8527 71CBF1_SM ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.06 0.8527 233OAF1_YPD Dsds3 Keogh05 0.06 0.8535 53DIG1_Alpha IOC4 Hughes00 -0.06 0.8537 59SUT1_YPD SSD1-V Kaeberlein04 0.06 0.8539 68MBP1_H2O2Lorpd3_del Sabet04 0.06 0.8539 56SUM1_YPD HST3 Hughes00 -0.06 0.8542 58HAP4_YPD hat1D Durant06 0.06 0.8543 49PHO4_YPD WT_V71R Chitikila_02 0.06 0.8546 63DIG1_Alpha ISW1 Hughes00 -0.06 0.8546 60PHO4_YPD hat1D_taf1-ts2Durant06 0.06 0.8547 61DIG1_BUT14 WT_N69S Chitikila_02 0.06 0.8547 54RTG3_RAPA Deaf3 Keogh05 -0.06 0.8554 46REB1_H2O2Hi VID21 Krogan04 -0.06 0.8554 55YAP7_H2O2Lo SAP30 Hughes00 0.06 0.8554 150DIG1_BUT14 DT_WT Chitikila_02 -0.06 0.8554 62DIG1_BUT14 SIR1 Hughes00 0.06 0.8556 63NDD1_YPD ISW2 Hughes00 -0.06 0.8557 85YAP6_YPD HST3 Hughes00 -0.06 0.8559 90NRG1_YPD hmr Meneghini03 -0.06 0.856 71SKN7_YPD PCH1 Hughes00 -0.06 0.8562 66RIM101_H2O2Loisw2_sin3_vs._sin3Fazzio01 0.06 0.8563 52AFT2_H2O2Hi Drco1 Keogh05 -0.06 0.8566 59CIN5_H2O2Lo SWD2 Mnaimneh_04 0.06 0.8566 127DIG1_Alpha 0.1%_MMS Attikum04 -0.06 0.8569 42DIG1_Alpha YNG2 Krogan04 -0.06 0.8569 54MSN4_RAPA Dume1 Keogh05 0.06 0.8573 49SKN7_H2O2Hi rpd3_H3dN_v_H3dNSabet04 0.06 0.8573 92DIG1_BUT14 WT_V71R Chitikila_02 0.06 0.8576 57STE12_BUT14 isw2_rpd3_vs._rpd3Fazzio01 0.06 0.8576 127SWI5_YPD SIN3 Hughes00 -0.06 0.8578 99MCM1_Alpha H4_2-26 Sabet04 0.06 0.8578 103GCN4_YPD Deaf3 Keogh05 0.06 0.8584 62

STP1_SM taf1-ts2_spt3_E240KHuisinga04 -0.06 0.8585 65UME6_H2O2Hisir2 Meneghini03 0.06 0.8588 99ACE2_YPD Dsin3 Keogh05 0.06 0.859 65HSF1_H2O2Lohmr Meneghini03 -0.06 0.8592 100HSF1_H2O2Hi hmr Meneghini03 -0.06 0.8593 122MCM1_YPD Dpho23 Keogh05 0.06 0.8594 76DAL82_SM WT Durant06 -0.06 0.8595 53MGA1_YPD hos2_del Bernstein_00_affydeletions0.06 0.8595 60TYE7_YPD hht2_K4914182327GMartin04 0.06 0.8596 51GCN4_RAPA hat2_vs._hat1Rosaleny05 0.06 0.86 157DIG1_BUT14 swr1 Meneghini03 0.06 0.86 53ACE2_YPD isw2_rpd3 Fazzio01 -0.06 0.8601 74OAF1_YPD rpd3_H4KQ_v_H4KQSabet04 0.06 0.8602 55SWI5_YPD rpd3 Fazzio01 0.06 0.8603 93GCN4_RAPA WT_Null_K Chitikila_02 -0.06 0.8606 154RPN4_H2O2Lohat2_vs._hat1Rosaleny05 0.06 0.8606 93MGA1_YPD hos3_del Bernstein_00_affydeletions-0.06 0.8606 59YAP6_YPD EAF5 Krogan04 0.06 0.861 84RPN4_H2O2LoMOT1-42 Dasgupta02 0.06 0.8611 100YAP6_YPD sas3D Durant06 0.06 0.8614 71CIN5_YPD SAP30 Hughes00 -0.06 0.8615 150ASH1_BUT14 taf1-ts2_25C Huisinga04 -0.06 0.8618 45GLN3_RAPA Drxt1 Keogh05 -0.06 0.8619 68OAF1_YPD WT_TAF1_SPT3Huisinga04 -0.06 0.862 56FKH1_YPD WT_F182V Chitikila_02 0.06 0.8623 112SUT1_YPD EPL1 Mnaimneh_04 -0.06 0.8627 69MCM1_YPD taf1-ts2_GCN5Huisinga04 0.06 0.8628 72RCS1_H2O2LoSSD1-V Kaeberlein04 0.06 0.8629 254CIN5_H2O2Hi ISW1_ISW2 Hughes00 0.06 0.863 79DAL82_SM SGF11 Ingvarsdottir05 0.06 0.8636 43CIN5_H2O2Hi esa1-414 Durant06 0.06 0.8638 69PHO4_YPD swi1_minimal_medium_experimentSudarsanam00 0.06 0.8639 71ROX1_YPD ARP4 Mnaimneh_04 0.06 0.8639 67MSN4_RAPA hht2_K914182327GMartin04 0.06 0.8643 35MCM1_YPD ubp10sir4 Orlandi04 0.06 0.8644 50MBP1_YPD ubp10 Orlandi04 0.06 0.8645 91MSN4_RAPA swi1_rich_medium_experimentSudarsanam00 0.06 0.8647 54HSF1_H2O2Hi hht2_K4914182327GMartin04 -0.06 0.8651 99GLN3_RAPA WT_TAF1_GCN5Huisinga04 0.06 0.8652 66CIN5_H2O2Hi Drpd3 Keogh05 0.06 0.8653 73DIG1_Alpha spt10_del Xu05 -0.06 0.8655 58YAP7_H2O2Lo gcn5_KQL Huisinga04 0.06 0.8657 135MBP1_H2O2Hiubp10 Orlandi04 -0.06 0.8658 90DIG1_Alpha UBP8 Hughes00 0.06 0.8659 60GCN4_YPD SGF11 Ingvarsdottir05 0.06 0.8664 66OAF1_YPD hat1_vs.YPH250Rosaleny05 -0.06 0.8666 54CBF1_SM DT_V161E Chitikila_02 0.06 0.8668 262RTG3_RAPA spt10_del Xu05 0.06 0.8668 52SWI5_YPD isw2_rpd3 Fazzio01 0.06 0.8669 94STE12_Alpha spt10 Eriksson05 -0.06 0.8669 113RCS1_H2O2LoYNG2 Krogan04 0.06 0.8671 247NDD1_YPD rpd3_c.i. Fazzio01 -0.06 0.8675 80REB1_YPD Drco1 Keogh05 0.06 0.8679 139

DAL82_RAPA WT_Null_K Chitikila_02 -0.06 0.868 51PHD1_YPD WT_TAF1_GCN5Huisinga04 -0.06 0.8682 66SUM1_YPD YNG2 Krogan04 0.06 0.8684 46DIG1_Alpha hht2_K4G Martin04 -0.06 0.8686 42YAP1_YPD RAD6_haploid Hughes00 0.06 0.8687 70MCM1_YPD rpd3 Fazzio01 0.06 0.869 73PUT3_H2O2Lo delta_ssd1 Kaeberlein04 0.06 0.8693 87MCM1_YPD DT_WT Chitikila_02 0.06 0.8693 72STE12_BUT90 hat1_vs.YPH250Rosaleny05 0.06 0.8696 74STE12_BUT14 UBP8 Ingvarsdottir05 0.06 0.8698 121DAL82_RAPA isw2 Fazzio01 -0.06 0.8699 54YAP6_H2O2Lo EAF7 Krogan04 -0.06 0.8699 54GCN4_RAPA gcn5 Huisinga04 -0.06 0.8702 153MSN2_H2O2HiDT_V71R Chitikila_02 -0.06 0.8702 78YAP6_H2O2Lo taf1-ts2_spt3_E240KHuisinga04 -0.06 0.8702 48SWI6_YPD Drxt2 Keogh05 0.06 0.8704 146PHO4_YPD taf1-ts2_SPT3 Huisinga04 -0.06 0.8705 70PUT3_H2O2Lo WT_V161E Chitikila_02 -0.06 0.8706 79REB1_YPD SWR1 Krogan04 -0.05 0.8714 129YAP7_H2O2Lo hat1D Durant06 0.05 0.8714 116MSN2_H2O2Hiisw2 Fazzio01 -0.05 0.8716 75FKH2_YPD Drxt1 Keogh05 -0.05 0.8719 121SUT1_YPD HAT2 Hughes00 0.05 0.872 69OAF1_YPD HTZ1 Krogan04 -0.05 0.872 56ACE2_YPD WT_TAF1_SPT3Huisinga04 0.05 0.8722 76STE12_BUT90 hpa2D_taf1-ts2Durant06 0.05 0.8726 61SUT1_YPD rpd3_H3dN_v_H3dNSabet04 0.05 0.8727 65GCN4_SM WT_Null_K Chitikila_02 -0.05 0.8727 178MCM1_YPD gcn5D Durant06 0.05 0.8728 62REB1_H2O2Hi YNG2 Krogan04 0.05 0.8733 56STE12_Alpha Hda1_del Bernstein02 0.05 0.8733 112YAP6_H2O2Lo WT_V161R_K Chitikila_02 -0.05 0.8735 53STP1_SM isw2_rpd3 Fazzio01 0.05 0.8736 67MBP1_H2O2LoDrxt2 Keogh05 0.05 0.8736 54STE12_BUT14 hht2_K914182327GMartin04 0.05 0.8736 107ACE2_YPD DT_N69R Chitikila_02 -0.05 0.8739 75DAL82_SM sir2 Meneghini03 -0.05 0.8747 55MCM1_YPD taf1-ts2_25C Huisinga04 0.05 0.8748 72OAF1_YPD ino80 Attikum04 0.05 0.8751 45TYE7_YPD rpd3_del Sabet04 -0.05 0.8756 55RTG3_RAPA SWC6_(VPS71)Krogan04 -0.05 0.8762 43STP1_SM WT_TAF1_GCN5Huisinga04 -0.05 0.8763 66UME6_H2O2HiSPT3 Ingvarsdottir05 0.05 0.8763 89PHO4_YPD isw2_c.i. Fazzio01 0.05 0.8765 71PHO4_YPD snf2_rich_medium_experimentSudarsanam00 -0.05 0.8765 71ROX1_YPD hat1_vs.YPH250Rosaleny05 -0.05 0.8767 64PHO4_YPD taf1-ts2 Durant06 0.05 0.8769 70OAF1_YPD SPT3 Ingvarsdottir05 -0.05 0.8769 51STP1_SM Drxt2 Keogh05 -0.05 0.8772 62YAP6_H2O2Hi H3_1-28 Sabet04 0.05 0.8774 71MCM1_Alpha ubp10sir4 Orlandi04 0.05 0.8775 68PHD1_YPD ZDS1 Hughes00 -0.05 0.8776 65STP1_SM DT_V161R_L Chitikila_02 -0.05 0.8783 62

MSN4_RAPA H3KQ Sabet04 -0.05 0.8786 52RPN4_H2O2LoDdep1 Keogh05 0.05 0.8786 98FKH2_YPD H3KQ Sabet04 -0.05 0.8787 119TYE7_YPD UBP8 Ingvarsdottir05 -0.05 0.8788 52MCM1_YPD MOT1-42 Dasgupta02 0.05 0.8789 77MBP1_YPD IOC4 Hughes00 -0.05 0.879 129STP1_SM taf1-ts2_gcn5 Huisinga04 0.05 0.8793 64RLM1_YPD Dsin3 Keogh05 -0.05 0.8797 45STE12_BUT14 ISW1_ISW2 Hughes00 -0.05 0.8798 128PHO4_YPD sin3 Fazzio01 -0.05 0.8799 71HAP4_YPD Drco1 Keogh05 0.05 0.88 64PHO4_YPD DT_V161E Chitikila_02 0.05 0.8801 68UME6_H2O2Hihht2_K4914182327GMartin04 0.05 0.8803 76PUT3_H2O2Lo WT_Null_L Chitikila_02 -0.05 0.8803 78CBF1_SM Set1_del Bernstein02 -0.05 0.8806 273AFT2_H2O2Lo SPT8 Ingvarsdottir05 -0.05 0.8806 87RCS1_H2O2LoSWC6_(VPS71)Krogan04 0.05 0.8807 242RLM1_YPD hht2_K27G Martin04 -0.05 0.881 42AFT2_H2O2Lo isw2_rpd3 Fazzio01 -0.05 0.8813 95UME6_YPD WT_N69S Chitikila_02 -0.05 0.8814 116OAF1_YPD taf1-ts2_gcn5_KQLHuisinga04 -0.05 0.8814 56CIN5_H2O2Hi hht2_K4914182327GMartin04 -0.05 0.8815 53STP1_SM SIR1 Hughes00 0.05 0.8816 65RPN4_H2O2LoSIN3 Hughes00 0.05 0.882 99CIN5_H2O2Hi SSD1-V Kaeberlein04 -0.05 0.8821 80FKH2_H2O2Hi rsc3-2 Angus-Hill_01 -0.05 0.8822 99STE12_YPD WT_WT Chitikila_02 -0.05 0.8823 46SUT1_YPD SWC6_(VPS71)Krogan04 -0.05 0.8828 61DIG1_Alpha swi1_minimal_medium_experimentSudarsanam00 -0.05 0.8829 59ACE2_YPD ARD1 Hughes00 -0.05 0.883 79CIN5_H2O2Hi Dume1 Keogh05 -0.05 0.8831 76PHD1_YPD Drco1 Keogh05 0.05 0.8833 65PHD1_YPD WT_TAF1_SPT3Huisinga04 -0.05 0.8833 64MCM1_YPD hpa2D_taf1-ts2Durant06 -0.05 0.8835 51ROX1_YPD gcn5D Durant06 -0.05 0.8836 55SUM1_YPD ARD1 Hughes00 -0.05 0.8838 58RCS1_H2O2Hi H4KQ Sabet04 -0.05 0.8839 50FKH1_YPD WT_TAF1_GCN5Huisinga04 0.05 0.8843 141FKH1_YPD WT_TAF1_SPT3Huisinga04 -0.05 0.8844 140RTG3_RAPA elp3D Durant06 0.05 0.8846 41FKH1_YPD hmr Meneghini03 0.05 0.8847 139CIN5_YPD Deaf3 Keogh05 -0.05 0.8848 135REB1_YPD SGF11 Ingvarsdottir05 -0.05 0.8849 120REB1_YPD hat1D_taf1-ts2Durant06 -0.05 0.8852 120RIM101_H2O2Lo_SWC2_(VPS72)Krogan04 0.05 0.8855 51MBP1_YPD ubp10sir4 Orlandi04 -0.05 0.8858 96STE12_BUT14 WT_WT Chitikila_02 0.05 0.8861 118CBF1_SM MOT1-14 Dasgupta02 0.05 0.8864 276MBP1_H2O2LoARP4 Mnaimneh_04 -0.05 0.8865 58NDD1_YPD HTZ1 Krogan04 0.05 0.8866 78REB1_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.05 0.8867 115TYE7_YPD hda1_del Bernstein_00_affydeletions0.05 0.8867 54RCS1_H2O2Lohat1D Durant06 -0.05 0.8869 206

REB1_H2O2Hi hht2_K27G Martin04 -0.05 0.8871 50ACE2_YPD hat1D Durant06 -0.05 0.8871 55PHO4_YPD SGF11 Ingvarsdottir05 -0.05 0.8872 57SKN7_YPD ZDS1 Hughes00 -0.05 0.8874 65RTG3_RAPA RAD6_haploid Hughes00 0.05 0.8874 52MCM1_YPD Dsin3 Keogh05 0.05 0.8875 63STP1_SM ino80_del Mizuguch04 -0.05 0.8879 68AFT2_H2O2Hi hda1_del Bernstein_00_affydeletions-0.05 0.8881 53ABF1_YPD DT_V161R_L Chitikila_02 0.05 0.8883 252STP1_SM HST3 Hughes00 0.05 0.8883 67RTG3_RAPA rpd3_del Sabet04 -0.05 0.8885 50MCM1_Alpha rpd3_del Sabet04 0.05 0.8885 103MGA1_YPD IOC4 Hughes00 0.05 0.8885 62AFT2_H2O2Hi RAD6_haploid Hughes00 0.05 0.8886 61MBP1_H2O2Hi rpd3_H3dN_v_H3dNSabet04 -0.05 0.8886 129YAP6_H2O2Lo WT_V161R_L Chitikila_02 -0.05 0.8886 55SUM1_YPD HTZ1 Krogan04 0.05 0.8893 53SKN7_YPD hmr Meneghini03 0.05 0.8895 66TYE7_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 0.05 0.8896 51YAP1_YPD isw2_c.i. Fazzio01 0.05 0.8898 68MGA1_YPD SGF11 Ingvarsdottir05 0.05 0.8899 57DAL82_SM Dsds3 Keogh05 0.05 0.89 54UME6_H2O2HiWT_TAF1_GCN5Huisinga04 -0.05 0.8901 99FKH1_YPD hht2_K4G Martin04 -0.05 0.8901 121SWI5_YPD hos2_del Bernstein_00_affydeletions0.05 0.8904 85RCS1_H2O2LoDsin3 Keogh05 -0.05 0.8904 226STP1_SM DT_V161E Chitikila_02 0.05 0.8905 64MGA1_YPD EAF7 Krogan04 0.05 0.8906 60PHO4_YPD WT Durant06 0.05 0.8907 66MGA1_YPD hht2K9131823GMartin04 -0.05 0.8908 48FKH2_H2O2Hi H3_1-28 Sabet04 0.05 0.891 103CIN5_H2O2Hi WT_TAF1_GCN5Huisinga04 -0.04 0.8915 80PHO4_YPD isw2_sin3_vs._sin3Fazzio01 0.04 0.8916 71MSN2_H2O2Hihat2_vs._YPH250Rosaleny05 -0.04 0.8916 76RPN4_H2O2LoHIR2 Hughes00 0.04 0.8918 98ASH1_BUT14 spt10 Eriksson05 -0.04 0.8919 50PUT3_H2O2Lo hos3_del Bernstein_00_affydeletions0.04 0.892 81MSN4_RAPA ARP4 Mnaimneh_04 -0.04 0.8921 54DAL81_RAPA hpa2D Durant06 -0.04 0.8928 77RTG3_RAPA hat1D Durant06 -0.04 0.8931 36MCM1_Alpha YNG2 Mnaimneh_04 -0.04 0.8939 106PHD1_BUT90 SAP30 Hughes00 0.04 0.8941 105STE12_YPD Drco1 Keogh05 0.04 0.8942 53MCM1_YPD spt10_del Xu05 -0.04 0.8942 75TYE7_YPD Dume1 Keogh05 0.04 0.8943 53PHO4_YPD gcn5D_taf1-ts2Durant06 -0.04 0.8947 67MBP1_H2O2Lorpd3_H3dN_v_H3dNSabet04 -0.04 0.8947 56MCM1_YPD Drco1 Keogh05 -0.04 0.8947 76DAL81_RAPA UBP8 Hughes00 -0.04 0.8952 95FKH1_YPD spt10 Eriksson05 -0.04 0.8952 140RCS1_H2O2Loubp10sir4 Orlandi04 0.04 0.8954 190MCM1_YPD WT_Null_L Chitikila_02 -0.04 0.8954 74MCM1_Alpha WT_V71R Chitikila_02 -0.04 0.8957 98

CIN5_H2O2Hi Ddep1 Keogh05 0.04 0.8958 75DAL82_SM UBP8 Hughes00 0.04 0.896 55MSN2_H2O2Hiisw2_rpd3 Fazzio01 -0.04 0.896 75GCN4_YPD rpd3_H4KQ_v_H4KQSabet04 -0.04 0.8963 75UME6_H2O2HiSGF11 Ingvarsdottir05 0.04 0.8965 86TYE7_YPD htz1_hmr Meneghini03 0.04 0.8967 53STP1_SM YNG2 Mnaimneh_04 0.04 0.8968 68GCN4_SM isw2_ume6 Fazzio01 -0.04 0.8973 183FKH1_YPD set1 Boa03 0.04 0.8973 141MGA1_YPD ubp10 Orlandi04 -0.04 0.8973 34YAP7_H2O2Lo SWC6_(VPS71)Krogan04 -0.04 0.8975 140REB1_YPD WT_Null_L Chitikila_02 0.04 0.8976 131YAP1_YPD hht2K9131823GMartin04 -0.04 0.8976 62RTG3_RAPA gcn5_KQL Huisinga04 -0.04 0.898 46REB1_YPD _SWC2_(VPS72)Krogan04 0.04 0.8984 129MCM1_Alpha DT_V161R_K Chitikila_02 0.04 0.8984 103HAP4_YPD hda1_del Bernstein_00_affydeletions0.04 0.8987 59UME6_YPD set1 Boa03 0.04 0.899 128HAP4_YPD Hda1_del Bernstein02 0.04 0.8993 67YAP6_YPD rsc30_null Angus-Hill_01 0.04 0.8994 90MBP1_H2O2HiSWD2 Mnaimneh_04 -0.04 0.8994 133MBP1_H2O2Lospt3_E240K Huisinga04 -0.04 0.8994 49SKN7_H2O2HiSIN3 Hughes00 0.04 0.8998 97NDD1_YPD hat1D Durant06 0.04 0.8998 69RPN4_H2O2Lorsc30_null Angus-Hill_01 -0.04 0.9 99FKH1_YPD WT_V161E Chitikila_02 -0.04 0.9 132HSF1_H2O2LoWT_WT Chitikila_02 0.04 0.9002 99CBF1_SM MED2_haploid Hughes00 0.04 0.9003 278DAL82_RAPA hht2_K49141823GMartin04 0.04 0.9005 40YAP7_H2O2Hi RAD6_haploid Hughes00 0.04 0.9006 139PUT3_H2O2Lo hos2_del Bernstein_00_affydeletions-0.04 0.9007 80SWI5_YPD hos3_del Bernstein_00_affydeletions-0.04 0.9009 87OAF1_YPD rpd3_c.i. Fazzio01 -0.04 0.9009 56DAL82_SM spt10_del Xu05 0.04 0.901 53DAL82_SM ino80_+_0.1%_MMS_vs._ino80Attikum04 0.04 0.9011 40MSN4_RAPA SWR1 Krogan04 0.04 0.9016 47TYE7_YPD hht2_K49141823GMartin04 -0.04 0.9019 50STP1_SM DT_WT Chitikila_02 -0.04 0.9019 63RCS1_H2O2Hi hpa2D Durant06 -0.04 0.9022 42ACE2_YPD SPT8 Ingvarsdottir05 -0.04 0.9022 78CBF1_SM Drxt1 Keogh05 0.04 0.9025 277DIG1_BUT14 arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.04 0.9026 55RCS1_H2O2Hi ARP4 Mnaimneh_04 0.04 0.9028 52STE12_YPD WT_V161E Chitikila_02 -0.04 0.9029 48CIN5_H2O2Hi SPT3 Ingvarsdottir05 -0.04 0.9032 66RCS1_H2O2LoWT_N69R Chitikila_02 0.04 0.9032 227MCM1_Alpha PCH1 Hughes00 -0.04 0.9034 105ASH1_BUT14 SGF11 Ingvarsdottir05 -0.04 0.9034 43DAL82_RAPA UBP8 Ingvarsdottir05 0.04 0.9035 48YAP6_H2O2Lo spt10 Eriksson05 0.04 0.9037 54NRG1_YPD WT_WT Chitikila_02 0.04 0.9038 66FKH1_YPD HAT2 Hughes00 -0.04 0.9045 141MGA1_YPD hat1_vs.YPH250Rosaleny05 0.04 0.9053 59

YAP7_H2O2Lo set1 Boa03 -0.04 0.9056 147ABF1_YPD IOC4 Hughes00 0.04 0.9058 262MSN4_H2O2Hihat2_vs._YPH250Rosaleny05 -0.04 0.906 67ASH1_BUT14 SIR4 Hughes00 -0.04 0.906 50STE12_Alpha DT_V161R_L Chitikila_02 -0.04 0.9061 103XBP1_H2O2Lo hpa2D Durant06 -0.04 0.9062 45REB1_YPD ISW1 Hughes00 0.04 0.9063 144RCS1_H2O2LoH4KQ Sabet04 -0.04 0.9064 253UME6_H2O2HiHDA1 Hughes00 -0.04 0.9066 101RCS1_H2O2Hi DT_V161R_L Chitikila_02 0.04 0.9069 47REB1_YPD H4KQ Sabet04 -0.04 0.907 141YAP6_H2O2Lo spt10_del Xu05 0.04 0.907 57SKN7_YPD Ddep1 Keogh05 -0.04 0.9074 62AFT2_H2O2Hi Hda1_del Bernstein02 -0.04 0.9074 61RCS1_H2O2Lohat2_vs._hat1Rosaleny05 -0.04 0.9075 245RTG3_RAPA ume6_del Bernstein_00_affydeletions0.04 0.9078 48REB1_H2O2Hi hos3_del Bernstein_00_affydeletions0.04 0.9081 56DAL82_SM arp8_+_0.1%_MMS_vs._arp8Attikum04 0.04 0.9083 39CIN5_H2O2Hi ARP4 Mnaimneh_04 0.04 0.9083 80STE12_Alpha hpa2D_taf1-ts2Durant06 -0.04 0.9083 74CIN5_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 0.04 0.9088 116PUT3_H2O2Lo SIR2 Hughes00 -0.04 0.9095 88RTG3_RAPA isw2_ume6 Fazzio01 -0.04 0.9097 51MBP1_YPD Dsin3 Keogh05 0.04 0.9098 108ROX1_YPD rsc30_null Angus-Hill_01 0.04 0.9099 67PHD1_YPD hpa2D Durant06 -0.04 0.9101 44RPN4_H2O2Lohmr Meneghini03 -0.04 0.9103 97REB1_H2O2Hi HAT2 Hughes00 -0.04 0.9105 58PHO4_YPD swr1 Meneghini03 -0.04 0.9107 63STE12_Alpha SAP30 Hughes00 -0.04 0.9108 114RCS1_H2O2LoHAT2 Hughes00 0.04 0.911 256YAP1_YPD set1 Boa03 0.04 0.9112 71MBP1_H2O2HiSGF11 Ingvarsdottir05 -0.04 0.9115 111GCR2_SM taf1-ts2_25C Huisinga04 0.04 0.9117 45SKN7_YPD MOT1-42 Dasgupta02 0.04 0.9118 67YAP7_H2O2Hi WT_V161R_L Chitikila_02 -0.03 0.9122 133YAP1_YPD MOT1-14 Dasgupta02 -0.03 0.9125 71STP1_SM taf1-ts2 Durant06 0.03 0.9125 67RCS1_H2O2LoSAP30 Hughes00 0.03 0.9126 252GCN4_SM Drco1 Keogh05 0.03 0.9128 179YAP1_YPD ino80 Attikum04 -0.03 0.9129 58REB1_YPD PCH1 Hughes00 0.03 0.9132 144STE12_Alpha TUP1_haploid Hughes00 -0.03 0.914 114MCM1_YPD Deaf3 Keogh05 0.03 0.9142 71FKH2_H2O2Hi UBP8 Ingvarsdottir05 -0.03 0.9145 102HSF1_H2O2Hi IOC4 Hughes00 -0.03 0.9145 122REB1_YPD SPT3 Ingvarsdottir05 -0.03 0.9147 124GCN4_YPD isw2_c.i._rpd3_c.i.Fazzio01 -0.03 0.9149 74FKH2_H2O2Hi RSC8 Mnaimneh_04 0.03 0.9153 106AFT2_H2O2Lo hos2_del Bernstein_00_affydeletions-0.03 0.9154 86MBP1_H2O2LoRAD6_haploid Hughes00 -0.03 0.9155 56ROX1_YPD delta_ssd1 Kaeberlein04 -0.03 0.916 67GCN4_SM YAF9 Krogan04 0.03 0.9161 179

RTG3_RAPA SWR1 Krogan04 0.03 0.9162 45CBF1_SM SSN6_haploid Hughes00 0.03 0.9164 275FKH1_YPD ubp10 Orlandi04 0.03 0.9174 99RTG3_RAPA Ddep1 Keogh05 -0.03 0.9179 49GCR2_SM hat1D Durant06 -0.03 0.9181 47GLN3_RAPA hda1_del Bernstein_00_affydeletions-0.03 0.9188 64PUT3_H2O2Lo SWC6_(VPS71)Krogan04 -0.03 0.9189 79RTG3_RAPA DT_V161R_L Chitikila_02 0.03 0.9193 46HAP1_YPD ino80 Attikum04 -0.03 0.9193 111DIG1_Alpha esa1-414_taf1-ts2Durant06 0.03 0.9195 54DIG1_BUT14 DT_V161R_K Chitikila_02 -0.03 0.9196 59STE12_YPD WT_N69S Chitikila_02 0.03 0.9198 44GCR2_SM sin3 Fazzio01 0.03 0.92 52DIG1_BUT14 Dpho23 Keogh05 -0.03 0.92 63GCN4_YPD hat2_vs._hat1Rosaleny05 0.03 0.92 72YAP1_YPD ARD1 Hughes00 0.03 0.9203 71MCM1_YPD PCH1 Hughes00 -0.03 0.9203 76REB1_H2O2Hi taf1-ts2 Durant06 -0.03 0.9209 56XBP1_H2O2Lo BUR6 Geisberg_01 -0.03 0.9211 61SWI5_YPD HAT2 Hughes00 0.03 0.9215 100OAF1_YPD htz1_hmr Meneghini03 0.03 0.9217 58UME6_YPD DT_V161R_L Chitikila_02 0.03 0.9223 121FKH2_H2O2Hi HAT2 Hughes00 -0.03 0.9223 105YAP6_H2O2Hi SAP30 Hughes00 -0.03 0.9223 78UME6_YPD SPT3 Ingvarsdottir05 0.03 0.9225 114RCS1_H2O2Hi EAF7 Krogan04 -0.03 0.923 46RCS1_H2O2LoDT_V71R Chitikila_02 -0.03 0.923 239MSN4_RAPA SPT8 Ingvarsdottir05 0.03 0.9233 46RCS1_H2O2Hi hos3_del Bernstein_00_affydeletions0.03 0.9237 46NRG1_H2O2HiWT_TAF1_SPT3Huisinga04 0.03 0.9241 115DAL82_RAPA arp8 Attikum04 0.03 0.9244 42PHD1_YPD _SWC2_(VPS72)Krogan04 -0.03 0.9245 60MBP1_H2O2LoH3KQ Sabet04 -0.03 0.9246 56DAL82_SM 0.1%_MMS Attikum04 0.03 0.9247 39TYE7_YPD rpd3 Fazzio01 -0.03 0.9255 54MCM1_Alpha snf2_rich_medium_experimentSudarsanam00 -0.03 0.9255 106ACE2_YPD taf1-ts2_spt3 Huisinga04 0.03 0.9256 76SUM1_YPD WT_Null_L Chitikila_02 0.03 0.9259 50MSN4_H2O2HiDT_V161R_K Chitikila_02 -0.03 0.9259 70GCN4_YPD sas3D Durant06 -0.03 0.9259 61ROX1_YPD SSD1-V Kaeberlein04 -0.03 0.9265 67MGA1_YPD hat1D Durant06 -0.03 0.9266 38OAF1_YPD WT_V71E Chitikila_02 -0.03 0.9266 52DAL82_RAPA htz1_del Mizuguch04 0.03 0.9271 56STP1_SM MED2_haploid Hughes00 0.03 0.9273 68HSF1_H2O2LoIOC4 Hughes00 -0.03 0.9274 99SKN7_H2O2Hi IOC4 Hughes00 -0.03 0.9276 96YAP6_H2O2Hi SWD2 Mnaimneh_04 0.03 0.9276 79STE12_BUT14 Drco1 Keogh05 -0.03 0.9276 123SKN7_YPD Dsap30 Keogh05 -0.03 0.9277 65RIM101_H2O2LoWT_TAF1_GCN5Huisinga04 -0.03 0.9277 53NRG1_H2O2HiDpho23 Keogh05 -0.03 0.9278 125REB1_H2O2Hi sas3D_taf1-ts2Durant06 -0.03 0.9281 55

FKH1_YPD sir2 Meneghini03 0.03 0.9282 140MCM1_Alpha SIR1 Hughes00 -0.03 0.9284 104STE12_BUT14 hat1_vs.YPH250Rosaleny05 -0.03 0.9284 120PHO4_YPD sas3D_taf1-ts2Durant06 0.03 0.9285 66FKH2_YPD hat1D Durant06 -0.03 0.9288 86YAP6_H2O2Hi YNG2 Krogan04 0.03 0.9289 77MBP1_H2O2LoYNG2 Krogan04 -0.03 0.929 57SWI4_YPD hht2_K49141823GMartin04 0.03 0.9294 128GCN4_RAPA swr1 Meneghini03 -0.03 0.9295 135MCM1_Alpha ino80 Attikum04 -0.03 0.9295 88RIM101_H2O2LoSWC6_(VPS71)Krogan04 0.03 0.9296 47YAP7_H2O2Lo htz1_hmr Meneghini03 0.03 0.9297 146DAL81_RAPA SGF11 Ingvarsdottir05 -0.03 0.9298 78YAP6_H2O2Lo WT_TAF1_GCN5Huisinga04 -0.03 0.9298 55ACE2_YPD hht2K9131823GMartin04 0.03 0.9298 65YAP1_YPD hos3_del Bernstein_00_affydeletions-0.03 0.9303 67SOK2_BUT14 WT_WT Chitikila_02 -0.03 0.9307 69MCM1_YPD SIR3 Hughes00 -0.03 0.9307 75SWI5_YPD ISW2 Hughes00 0.03 0.9313 100PHO4_YPD HIR2 Hughes00 0.03 0.9316 71REB1_YPD rpd3_H3dN_v_H3dNSabet04 0.03 0.9317 141RLM1_YPD Deaf3 Keogh05 -0.03 0.9318 47DIG1_Alpha DT_V71E Chitikila_02 -0.03 0.9318 55DAL81_RAPA WT_Null_K Chitikila_02 0.03 0.9319 88MCM1_YPD sas3D Durant06 0.03 0.9326 55MBP1_H2O2LoDrpd3 Keogh05 0.03 0.9327 53MSN4_RAPA WT_WT Chitikila_02 0.03 0.9328 50FKH1_YPD SPT8 Ingvarsdottir05 0.03 0.9328 130DAL81_RAPA isw2 Fazzio01 -0.03 0.9329 91REB1_H2O2Hi SPT3 Ingvarsdottir05 0.03 0.9329 52MBP1_YPD H4KQ Sabet04 -0.02 0.9333 126FKH2_H2O2Hi rpd3_H3dN_v_H3dNSabet04 -0.02 0.9336 103OAF1_YPD _SWC2_(VPS72)Krogan04 -0.02 0.9336 54TYE7_YPD Drpd3 Keogh05 0.02 0.9337 53OAF1_YPD taf1-ts2_SPT3 Huisinga04 -0.02 0.9338 51SWI5_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 -0.02 0.9339 79STP1_SM WT_TAF1_SPT3Huisinga04 0.02 0.9339 65YAP7_H2O2Hi Drco1 Keogh05 -0.02 0.9346 134FKH2_YPD Set1_del Bernstein02 -0.02 0.9346 121TYE7_YPD SWR1 Krogan04 -0.02 0.9347 53MGA1_YPD hht2_K27G Martin04 -0.02 0.9348 47CIN5_H2O2Hi DT_WT Chitikila_02 0.02 0.9349 76TYE7_YPD EAF7 Krogan04 0.02 0.935 54MCM1_YPD hht2_K4G Martin04 -0.02 0.935 60RCS1_H2O2LoPCH1 Hughes00 -0.02 0.9352 256REB1_H2O2Hi taf1-ts2_SPT3 Huisinga04 -0.02 0.9354 56REB1_YPD WT_N69S Chitikila_02 0.02 0.9355 127SUT1_YPD set1 Boa03 -0.02 0.9358 68YAP7_H2O2Hi SAP30 Hughes00 0.02 0.9359 140REB1_H2O2Hi WT Durant06 0.02 0.9361 54RTG3_RAPA isw2_rpd3_vs._rpd3Fazzio01 0.02 0.9364 51OAF1_YPD arp8 Attikum04 -0.02 0.9364 44DAL82_SM hpa2D Durant06 0.02 0.9367 42

DAL82_RAPA _SWC2_(VPS72)Krogan04 -0.02 0.9368 54YAP7_H2O2Lo Drxt1 Keogh05 0.02 0.937 149REB1_YPD HAT2 Hughes00 -0.02 0.9372 142RCS1_H2O2LoWT Durant06 0.02 0.9377 243YAP6_H2O2Hi delta_ssd1 Kaeberlein04 -0.02 0.9378 79MCM1_Alpha SIR4 Hughes00 0.02 0.9379 106TYE7_YPD ume6 Fazzio01 -0.02 0.9383 54OAF1_YPD IES6 Hughes00 0.02 0.9387 59OAF1_YPD ARP4 Mnaimneh_04 -0.02 0.9387 59PHD1_YPD SWC6_(VPS71)Krogan04 -0.02 0.9388 61DIG1_Alpha DT_V161R_L Chitikila_02 -0.02 0.9388 51ROX1_YPD snf2_rich_medium_experimentSudarsanam00 0.02 0.9391 67DAL82_SM hht2K9131823GMartin04 0.02 0.9395 41DAL82_SM Deaf3 Keogh05 0.02 0.9396 52MSN4_H2O2Hiume6 Fazzio01 0.02 0.9396 68FKH1_YPD spt3 Huisinga04 -0.02 0.9399 135MSN4_RAPA ISW2 Hughes00 -0.02 0.94 53GCN4_YPD isw2_sin3 Fazzio01 -0.02 0.9404 74GCR2_SM SPT3 Ingvarsdottir05 0.02 0.9408 49NDD1_YPD RAD6_haploid Hughes00 0.02 0.9408 85DAL82_RAPA HAT2 Hughes00 -0.02 0.941 55YAP7_H2O2Lo Drco1 Keogh05 0.02 0.9411 142MCM1_YPD ino80_del Mizuguch04 -0.02 0.9416 77RIM101_H2O2LoZDS1 Hughes00 0.02 0.9417 52DAL82_SM HST3 Hughes00 -0.02 0.9418 55YAP7_H2O2Hi WT_TAF1_SPT3Huisinga04 0.02 0.9419 139YAP6_H2O2Hi ZDS1 Hughes00 -0.02 0.9422 77HSF1_H2O2Hi hat2_vs._YPH250Rosaleny05 -0.02 0.9423 119HAP1_YPD WT_Null_L Chitikila_02 0.02 0.9423 135UME6_YPD ino80_+_0.1%_MMS_vs._ino80Attikum04 0.02 0.9425 88YAP6_H2O2Hi sas3D Durant06 0.02 0.9426 55YAP6_H2O2Lo hat2_vs._YPH250Rosaleny05 -0.02 0.9428 55DIG1_Alpha hat1_vs.YPH250Rosaleny05 0.02 0.943 55SOK2_BUT14 IOC4 Hughes00 -0.02 0.943 72PHD1_BUT90 hos3_del Bernstein_00_affydeletions-0.02 0.943 87OAF1_YPD gcn5 Huisinga04 0.02 0.9431 54PHO4_YPD 0.1%_MMS Attikum04 0.02 0.9432 57GLN3_RAPA Deaf3 Keogh05 0.02 0.9433 62OAF1_YPD swi1_rich_medium_experimentSudarsanam00 0.02 0.9434 59YAP6_H2O2Lo gcn5_KQL Huisinga04 0.02 0.9438 53ROX1_YPD PCH1 Hughes00 -0.02 0.9442 67SKN7_YPD arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.02 0.9442 48YAP6_H2O2Lo H4KQ Sabet04 0.02 0.9443 51GCN4_YPD rsc3-2 Angus-Hill_01 0.02 0.9445 71MBP1_YPD H3KQ Sabet04 -0.02 0.9445 126FKH1_YPD sas3D Durant06 -0.02 0.9446 116YAP1_YPD WT_Null_K Chitikila_02 0.02 0.9447 69PHO4_YPD hht2_K27G Martin04 0.02 0.9448 61RLM1_YPD WT_V161R_K Chitikila_02 -0.02 0.9448 51PHO4_YPD taf1-ts2_spt3_E240KHuisinga04 0.02 0.9452 63DAL82_SM snf2_rich_medium_experimentSudarsanam00 -0.02 0.9453 55TYE7_YPD rsc30_null Angus-Hill_01 0.02 0.9459 51STP1_SM SPT8 Ingvarsdottir05 0.02 0.9459 60

DIG1_BUT14 SIR4 Hughes00 0.02 0.946 62UME6_H2O2HiSIR3 Hughes00 0.02 0.9462 99RCS1_H2O2Hi SIR1 Hughes00 -0.02 0.9463 51GCN4_YPD hos2_del Bernstein_00_affydeletions-0.02 0.9464 73YAP6_H2O2Hi 0.1%_MMS Attikum04 -0.02 0.9465 48REB1_YPD hmr Meneghini03 -0.02 0.9467 137GCN4_RAPA hmr Meneghini03 0.02 0.9467 156TYE7_YPD swr1_del Mizuguch04 0.02 0.9468 56RPN4_H2O2LoWT_Null_L Chitikila_02 -0.02 0.947 95MSN4_RAPA elp3D_taf1-ts2Durant06 -0.02 0.9478 40HSF1_H2O2Hi SAP30 Hughes00 0.02 0.9478 122DIG1_BUT14 hht2_K49141823GMartin04 -0.02 0.9478 55STP1_SM HIR2 Hughes00 -0.02 0.948 68MSN4_RAPA WT Durant06 0.02 0.9482 51CIN5_YPD spt10 Eriksson05 0.02 0.9483 146MSN4_RAPA RAD6_haploid Hughes00 -0.02 0.9484 53REB1_H2O2Hi hpa2D Durant06 -0.02 0.9484 46REB1_H2O2Hi SGF11 Ingvarsdottir05 -0.02 0.9485 51MSN4_RAPA rpd3_c.i. Fazzio01 0.02 0.9486 53FKH1_YPD ZDS1 Hughes00 -0.02 0.9491 139GLN3_RAPA VID21 Krogan04 0.02 0.9493 60MSN4_RAPA hht2_K4G Martin04 0.02 0.9493 33YAP1_YPD DT_N69R Chitikila_02 -0.02 0.9494 70YAP6_H2O2Hi arp8_+_0.1%_MMS_vs._arp8Attikum04 -0.02 0.9494 50CIN5_H2O2Lo hpa2D Durant06 -0.02 0.9495 94STE12_BUT90 UBP8 Ingvarsdottir05 -0.02 0.9496 76GCN4_YPD Drco1 Keogh05 -0.02 0.9496 71MSN2_H2O2HiISW2 Hughes00 -0.02 0.9499 77CIN5_H2O2Lo WT_TAF1_SPT3Huisinga04 0.02 0.9501 121CIN5_YPD SWC6_(VPS71)Krogan04 0.02 0.9505 131OAF1_YPD Dpho23 Keogh05 -0.02 0.9505 58HAP1_YPD SWD2 Mnaimneh_04 -0.02 0.9514 141PHD1_YPD rsc3-2 Angus-Hill_01 0.02 0.9515 66UME6_YPD arp8 Attikum04 0.02 0.9516 84STP1_SM YAF9 Krogan04 0.02 0.9517 62STE12_YPD SPT3 Ingvarsdottir05 -0.02 0.9518 50STE12_BUT90 Drco1 Keogh05 0.02 0.9521 74HAP4_YPD ume6_del Bernstein_00_affydeletions0.02 0.9523 60YAP7_H2O2Lo YAF9 Krogan04 -0.02 0.9526 142REB1_YPD SIN3 Hughes00 -0.02 0.9531 144PHD1_BUT90 WT_Null_K Chitikila_02 -0.02 0.9532 103PUT3_H2O2Lo sir4 Orlandi04 -0.02 0.9542 55SWI6_YPD hat2_vs._YPH250Rosaleny05 0.02 0.9545 146MCM1_Alpha rsc30_null Angus-Hill_01 -0.02 0.9549 102YAP7_H2O2Hi WT Durant06 0.01 0.9551 132FKH2_YPD ume6_del Bernstein_00_affydeletions-0.01 0.9554 117GLN3_RAPA spt10 Eriksson05 -0.01 0.9556 67XBP1_H2O2Lo SSD1-V Kaeberlein04 -0.01 0.9557 68STE12_BUT90 hos3_del Bernstein_00_affydeletions-0.01 0.9559 73STP1_SM _SWC2_(VPS72)Krogan04 0.01 0.9565 61OAF1_YPD Hda1_del Bernstein02 0.01 0.9566 58GCN4_YPD YAF9 Krogan04 -0.01 0.9571 70CBF1_SM swi1_minimal_medium_experimentSudarsanam00 0.01 0.9572 278

FKH2_YPD WT_TAF1_SPT3Huisinga04 -0.01 0.9572 119STE12_YPD SIN3 Hughes00 -0.01 0.9573 54STE12_Alpha EPL1 Mnaimneh_04 -0.01 0.9574 115PHD1_YPD HST3 Hughes00 0.01 0.958 67RCS1_H2O2Lohpa2D Durant06 0.01 0.9583 209RCS1_H2O2LoRSC8 Mnaimneh_04 0.01 0.9587 259MCM1_YPD gcn5_KQL Huisinga04 0.01 0.9588 69YAP6_H2O2Hi BUR6 Geisberg_01 0.01 0.9595 71RCS1_H2O2Hi Deaf3 Keogh05 -0.01 0.9596 48FKH2_YPD ino80 Attikum04 0.01 0.9596 93STE12_BUT90 hht2_K49141823GMartin04 -0.01 0.9602 67RPN4_H2O2Lohat2_vs._YPH250Rosaleny05 -0.01 0.9603 94YAP7_H2O2Hi htz1_hmr Meneghini03 -0.01 0.9604 136DAL82_SM ARD1 Hughes00 -0.01 0.9611 54RTG3_RAPA WT_TAF1_GCN5Huisinga04 -0.01 0.9611 52SOK2_BUT14 ZDS1 Hughes00 0.01 0.9611 70MSN4_RAPA YAF9 Krogan04 -0.01 0.9612 49ROX1_YPD WT_TAF1_GCN5Huisinga04 -0.01 0.9614 67DIG1_Alpha spt10 Eriksson05 0.01 0.9617 57CBF1_SM rpd3_c.i. Fazzio01 0.01 0.9618 272STP1_SM isw2_c.i. Fazzio01 -0.01 0.9618 67RPN4_H2O2LoVID21 Krogan04 -0.01 0.962 96SUT1_YPD hht2_K4G Martin04 0.01 0.9621 49YAP1_YPD taf1-ts2_spt3_E240KHuisinga04 0.01 0.9624 64MCM1_YPD isw2 Fazzio01 -0.01 0.9624 73MCM1_YPD WT_TAF1_SPT3Huisinga04 0.01 0.963 74CIN5_H2O2Hi rpd3_del Sabet04 0.01 0.9633 74YAP6_H2O2Lo rsc30_null Angus-Hill_01 0.01 0.9638 57TYE7_YPD Deaf3 Keogh05 0.01 0.9642 51RLM1_YPD HST3 Hughes00 0.01 0.9644 53CIN5_H2O2Hi VID21 Krogan04 -0.01 0.9644 70FKH1_YPD gcn5D Durant06 -0.01 0.9646 116SKN7_H2O2Hi ino80 Attikum04 0.01 0.9652 70DIG1_Alpha TUP1_haploid Hughes00 -0.01 0.9653 59SWI6_YPD ino80 Attikum04 -0.01 0.9654 122AFT2_H2O2Lo hos3_del Bernstein_00_affydeletions-0.01 0.9656 86YAP7_H2O2Lo delta_ssd1 Kaeberlein04 -0.01 0.9658 151AFT2_H2O2Hi WT_N69S Chitikila_02 -0.01 0.966 51UME6_YPD delta_ssd1 Kaeberlein04 -0.01 0.9672 131MBP1_YPD hda1_del Bernstein_00_affydeletions-0.01 0.9675 122RIM101_H2O2LoSSD1-V Kaeberlein04 -0.01 0.9677 54PHO4_YPD esa1-414_taf1-ts2Durant06 0.01 0.9682 67SKN7_H2O2Lo0.1%_MMS Attikum04 -0.01 0.9684 148STE12_BUT14 YNG2 Mnaimneh_04 -0.01 0.9684 128CBF1_SM snf2_minimal_medium_experimentSudarsanam00 -0.01 0.9686 278MCM1_Alpha ume6_del Bernstein_00_affydeletions-0.01 0.9686 99MBP1_YPD BUR6 Geisberg_01 0.01 0.9686 122OAF1_YPD rpd3_del Sabet04 -0.01 0.9687 55DIG1_Alpha ubp10sir4 Orlandi04 -0.01 0.9692 33PHD1_BUT90 PCH1 Hughes00 0.01 0.9693 106REB1_H2O2Hi H3KQ Sabet04 -0.01 0.9699 57AFT2_H2O2Hi Deaf3 Keogh05 -0.01 0.9703 56YAP1_YPD EPL1 Mnaimneh_04 0.01 0.9706 72

UME6_YPD hht2_K4914182327GMartin04 0.01 0.9707 93DIG1_Alpha WT_V161R_L Chitikila_02 0.01 0.9708 51YAP7_H2O2Hi hht2K9131823GMartin04 -0.01 0.9712 123AFT2_H2O2Hi rpd3_H4KQ_v_H4KQSabet04 -0.01 0.9714 57RCS1_H2O2LoYNG2 Mnaimneh_04 -0.01 0.9717 258STP1_SM hat1D Durant06 0.01 0.9719 44CIN5_H2O2Hi ume6_del Bernstein_00_affydeletions-0.01 0.9719 68SUT1_YPD YAF9 Krogan04 0.01 0.972 64MSN4_RAPA MED2_haploid Hughes00 -0.01 0.9721 53RTG3_RAPA RSC8 Mnaimneh_04 -0.01 0.9724 52RLM1_YPD SGF11 Ingvarsdottir05 0.01 0.973 50CBF1_SM set1 Boa03 0.01 0.973 276CBF1_SM isw2_sin3 Fazzio01 0.01 0.9734 272DAL82_RAPA WT_N69S Chitikila_02 -0.01 0.9734 49OAF1_YPD esa1-414_taf1-ts2Durant06 -0.01 0.9734 55ASH1_BUT14 swr1_del Mizuguch04 -0.01 0.9735 50ACE2_YPD isw2_c.i._rpd3_c.i.Fazzio01 -0.01 0.9738 74RTG3_RAPA UBP8 Hughes00 -0.01 0.9739 51XBP1_H2O2Lo TAF2 Mnaimneh_04 -0.01 0.9743 68SWI6_YPD arp8 Attikum04 0.01 0.9748 123YAP6_YPD set1 Boa03 -0.01 0.9748 89HSF1_H2O2LoUBP8 Ingvarsdottir05 -0.01 0.9749 94CIN5_H2O2Lo delta_ssd1 Kaeberlein04 -0.01 0.9752 127YAP7_H2O2Lo isw2 Fazzio01 -0.01 0.9755 148STE12_BUT14 DT_Null Chitikila_02 -0.01 0.9755 119REB1_YPD WT_TAF1_SPT3Huisinga04 -0.01 0.9757 138PHD1_YPD hat2_vs._hat1Rosaleny05 -0.01 0.9758 61RLM1_YPD HIR2 Hughes00 0.01 0.976 54YAP1_YPD Drxt1 Keogh05 -0.01 0.9762 72YAP6_YPD SSD1-V Kaeberlein04 -0.01 0.9764 90GCR2_SM Drxt2 Keogh05 0.01 0.9768 54YAP6_YPD WT_TAF1_SPT3Huisinga04 0 0.9775 84DIG1_BUT14 EAF5 Krogan04 0 0.9775 59MCM1_YPD SSD1-V Kaeberlein04 0 0.9775 77MCM1_Alpha ISW2 Hughes00 0 0.9778 106NDD1_YPD sin3_del Bernstein_00_affydeletions0 0.9779 81NDD1_YPD H3KQ Sabet04 0 0.978 83REB1_YPD hpa2D Durant06 0 0.9782 117MCM1_Alpha Drco1 Keogh05 0 0.9784 101TYE7_YPD elp3D Durant06 0 0.9788 50DAL82_RAPA SAP30 Hughes00 0 0.9791 56YAP6_YPD WT_Null_L Chitikila_02 0 0.9792 87REB1_H2O2Hi WT_Null_L Chitikila_02 0 0.9794 55REB1_YPD ino80 Attikum04 0 0.9798 115DAL82_RAPA YAF9 Krogan04 0 0.9799 51HAP4_YPD hpa2D_taf1-ts2Durant06 0 0.9799 49MCM1_YPD elp3D_taf1-ts2Durant06 0 0.9801 54NDD1_YPD PCH1 Hughes00 0 0.9801 84OAF1_YPD DT_Null Chitikila_02 0 0.9802 53FKH2_YPD SSN6_haploid Hughes00 0 0.9803 120OAF1_YPD swr1_del Mizuguch04 0 0.9804 58REB1_H2O2Hi Drpd3 Keogh05 0 0.9805 54MSN4_RAPA esa1-414 Durant06 0 0.9807 47

DIG1_BUT14 WT_F182V Chitikila_02 0 0.9807 51NDD1_YPD DT_N69R Chitikila_02 0 0.9807 82SWI5_YPD YAF9 Krogan04 0 0.9808 95REB1_H2O2Hi Dpho23 Keogh05 0 0.9808 59YAP7_H2O2Hi DT_N69S Chitikila_02 0 0.9808 135NDD1_YPD spt10_del Xu05 0 0.9809 83FKH1_YPD TAF2 Mnaimneh_04 0 0.981 142FKH2_H2O2Hi ume6 Fazzio01 0 0.9812 104RTG3_RAPA htz1_hmr Meneghini03 0 0.9819 50ASH1_BUT14 sir2 Meneghini03 0 0.9819 48SWI5_YPD HST3 Hughes00 0 0.9821 99RCS1_H2O2Hi HTZ1 Krogan04 0 0.9822 47PHD1_YPD SWD2 Mnaimneh_04 0 0.9823 67DIG1_BUT14 Ddep1 Keogh05 0 0.9824 60DIG1_Alpha PCH1 Hughes00 0 0.983 58RLM1_YPD isw2 Fazzio01 0 0.9831 54DIG1_BUT14 WT_V161R_L Chitikila_02 0 0.9831 61REB1_H2O2Hi DT_WT Chitikila_02 0 0.9833 55REB1_YPD WT_N69R Chitikila_02 0 0.9834 128DIG1_BUT14 WT_WT Chitikila_02 0 0.9834 56RCS1_H2O2Hi ZDS1 Hughes00 0 0.9835 50RCS1_H2O2LoSIR3 Hughes00 0 0.9839 256RIM101_H2O2Lospt10_del Xu05 0 0.984 54DIG1_Alpha DT_N69R Chitikila_02 0 0.984 49NDD1_YPD DT_V71E Chitikila_02 0 0.9844 81AFT2_H2O2Hi gcn5D Durant06 0 0.9845 51MCM1_YPD SIR1 Hughes00 0 0.9846 76RPN4_H2O2LoSIR1 Hughes00 0 0.9847 98ABF1_YPD hmr Meneghini03 0 0.9848 259RCS1_H2O2Hi HIR2 Hughes00 0 0.9849 49YAP6_H2O2Lo ubp10 Orlandi04 0 0.9849 27UME6_H2O2HiHST3 Hughes00 0 0.9852 100PHO4_YPD htz1_sir2 Meneghini03 0 0.9854 71RLM1_YPD SSD1-V Kaeberlein04 0 0.9854 53TYE7_YPD hht2_K27G Martin04 0 0.9856 52AFT2_H2O2Lo spt10 Eriksson05 0 0.9857 94RTG3_RAPA DT_V161E Chitikila_02 0 0.9858 50OAF1_YPD hmr Meneghini03 0 0.9859 59STE12_BUT90 ino80 Attikum04 0 0.9866 66RCS1_H2O2Hi taf1-ts2_SPT3 Huisinga04 0 0.9871 45RPN4_H2O2LoDume1 Keogh05 0 0.9872 92RLM1_YPD Drxt2 Keogh05 0 0.9873 55YAP1_YPD YAF9 Krogan04 0 0.9874 67ACE2_YPD isw2 Fazzio01 0 0.9874 74MSN2_H2O2Hihat1D Durant06 0 0.9879 59DIG1_BUT14 DT_Null Chitikila_02 0 0.9879 57YAP7_H2O2Lo sas3D Durant06 0 0.988 125SKN7_H2O2HiZDS1 Hughes00 0 0.9883 96CIN5_H2O2Hi WT_Null_L Chitikila_02 0 0.9884 76SOK2_BUT14 hat2_vs._hat1Rosaleny05 0 0.9884 65ABF1_YPD SIN3 Hughes00 0 0.9885 265TYE7_YPD ISW2 Hughes00 0 0.9892 55DAL82_SM SAP30 Hughes00 0 0.9898 55

STE12_Alpha WT_V161E Chitikila_02 0 0.9898 109STE12_BUT14 taf1-ts2_spt3_E240KHuisinga04 0 0.9898 117MBP1_YPD WT_Null_L Chitikila_02 0 0.9899 121AFT2_H2O2Hi SWC6_(VPS71)Krogan04 0 0.9901 52CIN5_H2O2Hi Dsin3 Keogh05 0 0.9901 69REB1_H2O2Hi UBP8 Hughes00 0 0.9901 58REB1_H2O2Hi Ddep1 Keogh05 0 0.9901 54OAF1_YPD taf1-ts2_GCN5Huisinga04 0 0.9904 54GCN4_SM rsc3-2 Angus-Hill_01 0 0.9905 180MGA1_YPD DT_WT Chitikila_02 0 0.9905 59TYE7_YPD spt3_E240K Huisinga04 0 0.9906 45CIN5_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 0 0.9908 71REB1_H2O2Hi taf1-ts2_spt3_E240KHuisinga04 0 0.9913 52YAP1_YPD WT_TAF1_GCN5Huisinga04 0 0.9914 70MCM1_Alpha hos2_del Bernstein_00_affydeletions0 0.9914 98GCN4_YPD hda1_del Bernstein_00_affydeletions0 0.9915 73DAL82_SM DT_V161R_K Chitikila_02 0 0.9916 54YAP7_H2O2Lo WT_V161R_L Chitikila_02 0 0.9916 141STE12_Alpha DT_N69R Chitikila_02 0 0.9916 101GCN4_SM Deaf3 Keogh05 0 0.9917 160STE12_BUT14 swr1 Meneghini03 0 0.9919 105GCN4_YPD hht2K9131823GMartin04 0 0.9919 66NRG1_YPD taf1-ts2_gcn5_KQLHuisinga04 0 0.9919 60PHD1_YPD YNG2 Mnaimneh_04 0 0.992 67YAP7_H2O2Lo swi1_minimal_medium_experimentSudarsanam00 0 0.9921 151DIG1_Alpha WT_V161E Chitikila_02 0 0.9921 53FKH1_YPD sin3_del Bernstein_00_affydeletions0 0.9921 134MBP1_H2O2Lorsc3-2 Angus-Hill_01 0 0.9923 56MGA1_YPD DT_Null Chitikila_02 0 0.9928 56DIG1_BUT14 UBP8 Ingvarsdottir05 0 0.9931 62SWI5_YPD SGF11 Ingvarsdottir05 0 0.9932 84PUT3_H2O2Lo WT_V161R_L Chitikila_02 0 0.9935 84MCM1_YPD H4_2-26 Sabet04 0 0.9935 73NDD1_YPD isw2_rpd3_vs._rpd3Fazzio01 0 0.994 80MCM1_Alpha WT_V161R_L Chitikila_02 0 0.9941 101RCS1_H2O2Hi hos2_del Bernstein_00_affydeletions0 0.9942 46MBP1_YPD SIR4 Hughes00 0 0.9942 130DAL82_RAPA hht2_K4G Martin04 0 0.9944 40AFT2_H2O2Hi ume6_del Bernstein_00_affydeletions0 0.9945 51DAL81_RAPA rsc3-2 Angus-Hill_01 0 0.9947 93PHO4_YPD SIR3 Hughes00 0 0.995 70MBP1_H2O2LoWT_Null_L Chitikila_02 0 0.995 53SWI4_YPD Dsap30 Keogh05 0 0.9952 152OAF1_YPD sas3D Durant06 0 0.9952 48PHO4_YPD _SWC2_(VPS72)Krogan04 0 0.9953 66RLM1_YPD rpd3_H3dN_v_H3dNSabet04 0 0.9954 50YAP1_YPD isw2 Fazzio01 0 0.9955 68GCR2_SM H4_2-26 Sabet04 0 0.9957 54NRG1_YPD set1 Boa03 0 0.9959 72SUM1_YPD taf1-ts2 Durant06 0 0.996 54MBP1_H2O2Loelp3D_taf1-ts2Durant06 0 0.996 45SWI6_YPD Dsap30 Keogh05 0 0.9965 147PUT3_H2O2Lo sas3D Durant06 0 0.9966 76

STE12_BUT90 hht2_K4G Martin04 0 0.9966 67STP1_SM Deaf3 Keogh05 0 0.9967 59MBP1_H2O2LoDT_Null Chitikila_02 0 0.9967 55DIG1_BUT14 sas3D Durant06 0 0.9967 51TYE7_YPD hht2_K914182327GMartin04 0 0.9969 52SUM1_YPD taf1-ts2_GCN5Huisinga04 0 0.9972 50YAP6_H2O2Lo set1 Boa03 0 0.9972 58STE12_BUT90 hht2_K914182327GMartin04 0 0.9972 67STE12_BUT14 MOT1-42 Dasgupta02 0 0.9973 128REB1_YPD WT Durant06 0 0.9976 133STP1_SM hpa2D Durant06 0 0.9976 52DIG1_Alpha elp3D_taf1-ts2Durant06 0 0.9976 42PUT3_H2O2Lo hpa2D Durant06 0 0.9977 72STE12_BUT90 hht2_K27G Martin04 0 0.9978 67SWI5_YPD WT_Null_K Chitikila_02 0 0.9979 92GCN4_YPD sin3_del Bernstein_00_affydeletions0 0.9979 72ROX1_YPD hos3_del Bernstein_00_affydeletions0 0.998 52PHD1_YPD ubp10sir4 Orlandi04 0 0.9981 34STE12_YPD hat1D Durant06 0 0.9981 38FKH2_YPD SIR4 Hughes00 0 0.9983 121PHO4_YPD H4KQ Sabet04 0 0.9985 70FKH1_YPD gcn5D_taf1-ts2Durant06 0 0.9985 131FKH1_YPD hht2_K27G Martin04 0 0.9985 122STE12_BUT14 HDA1 Hughes00 0 0.9985 128MSN4_H2O2Hisnf2_rich_medium_experimentSudarsanam00 0 0.9986 70PUT3_H2O2Lo htz1_hmr Meneghini03 0 0.9987 86PUT3_H2O2Lo H4KQ Sabet04 0 0.9988 85XBP1_H2O2Lo EAF7 Krogan04 0 0.9989 64REB1_H2O2Hi rpd3_del Sabet04 0 0.999 57OAF1_YPD SIR1 Hughes00 0 0.999 58DAL81_RAPA sin3 Fazzio01 0 0.9992 91ASH1_BUT14 SPT3 Ingvarsdottir05 0 0.9992 43STP1_SM taf1-ts2_spt3 Huisinga04 0 0.9993 64STP1_SM ubp10 Orlandi04 0 0.9993 37PHD1_BUT90 SGF11 Ingvarsdottir05 0 0.9993 94YAP1_YPD rpd3_del Sabet04 0 0.9994 70STP1_SM rpd3 Fazzio01 0 0.9995 67DAL81_RAPA WT_TAF1_GCN5Huisinga04 0 0.9995 95RPN4_H2O2Lohpa2D Durant06 0 0.9996 86PHO4_YPD esa1-414 Durant06 0 0.9997 66CIN5_YPD hmr Meneghini03 0 0.9998 147AFT2_H2O2Hi YNG2 Mnaimneh_04 0 0.9999 61

Cohort MedianExpression Level at KS ValueTF Fraction at KS valueBG Fraction at KS valueKS value TF Expression level in Condition0.358 0.16 0.31 0.87 0.55 0.3350.551 0.31 0.32 0.89 0.56 0.2450.511 0.31 0.37 0.89 0.52 0.2450.382 0.22 0.35 0.91 0.55 0.3350.342 0.24 0.4 0.88 0.47 0.2820.195 0.16 0.44 0.88 0.43 0.0590.272 0.17 0.38 0.82 0.43 0.2820.308 0.24 0.41 0.87 0.46 0.3980.285 0.24 0.45 0.87 0.42 0.3980.398 0.22 0.26 0.9 0.64 0.3350.209 0.16 0.43 0.88 0.44 0.0590.551 0.28 0.24 0.86 0.62 0.2450.199 0.07 0.31 0.7 0.39 0.3180.229 0.2 0.47 0.87 0.4 0.3180.225 0.17 0.42 0.78 0.36 -0.031.006 0.42 0.26 0.84 0.57 3.1220.259 0.15 0.37 0.76 0.38 -0.03

-0.135 0.2 0.68 0.28 0.39 -0.6240.252 0.2 0.41 0.86 0.44 0.029

0.8 0.61 0.38 0.79 0.41 -0.01-0.66 -0.8 0.37 0.77 0.4 -1.150.382 0.22 0.31 0.86 0.55 0.2820.285 0.2 0.38 0.86 0.48 0.0290.76 0.29 0.22 0.63 0.4 -0.11

0.764 0.28 0.27 0.69 0.41 6.6430.176 0.03 0.34 0.81 0.46 0.3050.348 0.27 0.37 0.89 0.52 0.3980.528 0.3 0.38 0.78 0.4 3.1220.247 0.13 0.34 0.67 0.33 0.218

-0.175 0.06 0.61 0.21 0.4 -0.6240.76 0.31 0.24 0.64 0.39 -0.11

0.282 0.17 0.37 0.87 0.5 0.0590.87 0.81 0.44 0.8 0.36 -0.27

0.534 0.36 0.39 0.81 0.42 1.890.312 0.19 0.37 0.86 0.49 0.3180.441 0.41 0.45 0.79 0.34 0.3620.697 0.48 0.4 0.85 0.44 3.2750.598 0.56 0.45 0.79 0.34 0.008-0.78 -0.9 0.33 0.73 0.4 -1.050.68 0.62 0.46 0.8 0.33 -0.01

1.039 0.36 0.31 0.72 0.41 3.637-0.81 -0.8 0.44 0.76 0.32 -0.861.132 0.54 0.3 0.87 0.56 0.2950.413 0.41 0.49 0.79 0.3 0.3620.518 0.51 0.49 0.86 0.37 2.0490.179 0.04 0.29 0.6 0.3 0.1290.787 0.57 0.44 0.78 0.34 2.4111.91 0.66 0.31 0.79 0.47 6.643

0.229 0.24 0.5 0.84 0.34 0.0071.445 0.36 0.25 0.72 0.47 1.3250.292 0.27 0.45 0.85 0.4 0.267

0.8 0.47 0.3 0.73 0.43 1.1

-0.09 0 0.6 0.3 0.29 -0.010.78 0.5 0.32 0.68 0.35 -0.48

-0.87 -0.9 0.43 0.73 0.3 -0.340.52 0.41 0.39 0.69 0.29 0.008

0.186 0.19 0.5 0.81 0.31 0.1290.175 0.14 0.43 0.72 0.28 0.0390.189 0.11 0.38 0.68 0.3 0.007-0.71 -0.5 0.54 0.07 0.47 0.3350.614 0.45 0.37 0.72 0.34 -4.1370.664 0.29 0.33 0.78 0.44 0.7970.229 0.14 0.37 0.67 0.3 0.218

-0.156 -0.1 0.58 0.33 0.25 -0.181-0.85 -0.9 0.36 0.69 0.32 -0.32

-0.177 -0.2 0.43 0.13 0.29 0.0020.72 0.5 0.34 0.68 0.33 -0.48

0.306 0.27 0.37 0.89 0.51 -0.1340.79 0.66 0.45 0.8 0.34 2.411

2.428 0.92 0.32 0.83 0.51 0.122-0.177 -0.1 0.6 0.25 0.34 0.0860.302 0.53 0.56 0.87 0.31 2.049

-0.358 0.05 0.69 0.21 0.47 -0.6240.076 0.05 0.43 0.73 0.3 0.079

0.7 0.38 0.37 0.82 0.44 0.70.73 0.82 0.51 0.81 0.29 -0.27

0.979 0.49 0.36 0.85 0.48 3.2750.242 0.15 0.33 0.75 0.42 -0.03

-0.5 -0.7 0.26 0.81 0.54 -0.26-0.067 0 0.63 0.34 0.29 -0.14-0.264 -0.2 0.52 0.23 0.29 0.227-0.094 0 0.62 0.32 0.29 -0.01-1.111 -1.2 0.39 0.81 0.42 -1.596-0.78 -1 0.25 0.63 0.38 -1.051.182 0.38 0.28 0.72 0.44 3.6371.268 0.76 0.37 0.81 0.43 2.9430.235 0.18 0.44 0.77 0.33 0.2670.724 0.19 0.26 0.71 0.44 1.890.178 0.14 0.45 0.77 0.32 0.7750.265 0.28 0.5 0.77 0.27 -0.196-0.85 -1.1 0.27 0.58 0.3 -1.27

-0.538 -0.2 0.66 0.36 0.29 0.2990.435 0.32 0.44 0.71 0.26 0.332

-0.594 -0.5 0.53 0.2 0.32 0.2990.09 0.01 0.22 0.54 0.32 0.3310.93 0.57 0.4 0.78 0.37 6.643

-2.17 -1.7 0.58 0.86 0.27 -2.710.117 0.09 0.36 0.8 0.44 0.2020.318 0.24 0.42 0.7 0.28 0.0490.297 0.4 0.54 0.82 0.28 -0.0390.343 0.28 0.44 0.7 0.26 0.7160.123 0.05 0.29 0.64 0.35 0.3310.81 0.74 0.45 0.74 0.29 -0.07

-0.217 -0.2 0.49 0.21 0.27 0.077-1.032 -0.9 0.64 0.34 0.3 -0.794

0.063 0.02 0.35 0.6 0.25 -0.067-2.15 -2.1 0.49 0.76 0.26 -1.120.241 0.2 0.44 0.72 0.28 0.342

-0.921 -0.9 0.49 0.75 0.26 -1.43-0.92 -1.1 0.27 0.59 0.31 -1.33

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0.631 0.33 0.37 0.71 0.34 0.332-0.143 0 0.63 0.25 0.38 -0.01

-1.2 -1.2 0.42 0.81 0.39 -1.240.056 0.04 0.45 0.7 0.24 0.079

-1.017 -1.1 0.39 0.12 0.27 -0.9260.234 0.18 0.42 0.87 0.45 -0.0060.318 0.03 0.24 0.53 0.29 0.6310.318 0.18 0.29 0.7 0.4 1.066

-0.062 0 0.66 0.36 0.3 0.015-0.206 -0.1 0.7 0.29 0.4 -0.4630.173 0.14 0.44 0.77 0.33 0.775

-0.206 -0.1 0.55 0.27 0.27 -0.0270.279 0.11 0.34 0.73 0.38 0.115

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-0.777 -0.9 0.37 0.75 0.38 -0.804-0.123 0 0.66 0.37 0.28 -0.13-0.103 -0.2 0.35 0.56 0.21 0.0090.012 0.24 0.71 0.28 0.42 0.4010.21 0.08 0.28 0.62 0.34 00.3 0.22 0.43 0.67 0.24 0.022

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0.1 0.02 0.31 0.61 0.29 0.026-2.47 -1.9 0.62 0.87 0.25 -2.63-0.1 0 0.54 0.17 0.37 -0.14

0.465 0.53 0.5 0.86 0.36 2.0490.123 0.12 0.49 0.8 0.31 0.166

-0.9 -0.9 0.47 0.73 0.26 -0.341.8 1.44 0.45 0.87 0.42 6.643

-0.193 -0.3 0.42 0.17 0.25 0.181-1.94 -2 0.43 0.83 0.39 -1.410.76 0.66 0.42 0.71 0.28 -0.820.53 0.36 0.31 0.63 0.32 -4.137

0.828 0.79 0.46 0.75 0.28 -2.852-0.164 -0.1 0.56 0.25 0.31 -0.706-1.96 -2 0.46 0.83 0.36 -2.040.356 0.68 0.57 0.86 0.28 0.691

-0.727 -0.5 0.63 0.22 0.4 0.299-0.85 -0.9 0.4 0.73 0.32 -0.860.134 0.12 0.42 0.81 0.38 0.166-0.79 -0.9 0.36 0.74 0.37 -0.34-0.74 -0.7 0.44 0.81 0.36 -0.50.053 0.05 0.51 0.76 0.25 0.0190.528 0.35 0.33 0.71 0.38 0.332

-0.378 -0.2 0.64 0.24 0.39 -1.3970.46 0.3 0.38 0.69 0.31 0.947

-1.03 -1.1 0.33 0.53 0.2 -1.090.287 0.27 0.48 0.75 0.26 0.4340.129 0.12 0.47 0.79 0.31 0.2320.049 0.04 0.47 0.7 0.23 0.019-2.37 -2.3 0.47 0.67 0.19 -2.3

-0.944 -1.1 0.22 0.55 0.32 -1.1330.263 0.16 0.35 0.63 0.27 0.8070.133 0.07 0.3 0.66 0.35 0.155

-0.4 -0.2 0.6 0.32 0.28 0-2.17 -2.1 0.5 0.76 0.26 -3.15-0.18 -0.2 0.46 0.23 0.22 0.122

0.1 0 0.28 0.49 0.2 -0.3580.668 0.66 0.47 0.85 0.37 0.7160.226 0.31 0.54 0.81 0.27 0.342

-0.305 -0.5 0.28 0.64 0.35 -0.3030.266 0.1 0.35 0.63 0.27 0.270.302 0 0.18 0.46 0.28 0.5950.059 0 0.49 0.23 0.25 -0.679

-0.107 -0.1 0.4 0.1 0.29 -0.1270.591 0.4 0.32 0.68 0.35 0.0080.75 0.23 0.25 0.52 0.27 -0.82

-0.136 -0.2 0.39 0.13 0.25 0.195-0.502 -0.4 0.63 0.31 0.32 0.593-0.139 -0.3 0.23 0.42 0.19 -0.249-0.232 0 0.67 0.31 0.35 0.740.471 0.46 0.48 0.75 0.27 0.641

-0.157 -0.1 0.48 0.17 0.3 0.0860.112 0 0.25 0.5 0.24 -0.060.248 0.2 0.45 0.76 0.31 0.8530.93 0.7 0.4 0.72 0.32 1.11

-0.17 -0.2 0.4 0.17 0.22 0.0410.315 0.26 0.42 0.84 0.41 0.455-1.41 -1.4 0.43 0.77 0.34 -1.110.143 0.19 0.5 0.77 0.27 -3.2070.71 0.62 0.46 0.69 0.23 -0.07

0.129 0.09 0.39 0.75 0.35 0.0420.267 0.4 0.53 0.88 0.35 0.2180.354 0 0.12 0.5 0.37 0.6830.282 0.12 0.27 0.64 0.36 1.80.73 0.42 0.31 0.63 0.32 1.08

-0.2 -0.1 0.51 0.27 0.24 0.122-0.344 -0.3 0.5 0.13 0.37 -0.1920.143 0.17 0.52 0.76 0.23 0.0390.222 0.19 0.46 0.81 0.34 0.129

-0.117 -0.2 0.4 0.15 0.24 -0.09-1.22 -0.8 0.62 0.87 0.25 -1.57-0.31 0 0.81 0.42 0.38 -0.2090.57 0.65 0.51 0.78 0.26 0.844

-0.496 -0.3 0.52 0.75 0.23 -0.802-0.541 -0.9 0.18 0.49 0.31 -0.438-0.538 -0.2 0.81 0.46 0.35 -0.271-0.282 -0.2 0.58 0.21 0.36 -0.8380.143 0.14 0.48 0.83 0.35 0.321

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-0.186 -0.1 0.55 0.32 0.22 0.3070.74 0.62 0.43 0.79 0.36 -0.01

-0.314 -0.4 0.47 0.1 0.37 -0.838-0.165 -0.2 0.46 0.18 0.28 -0.427-2.384 -2 0.68 0.43 0.24 -2.642-0.74 -0.9 0.36 0.73 0.36 -1.360.083 0 0.16 0.5 0.34 -0.0670.301 0.09 0.23 0.54 0.31 0.014

-0.127 -0.1 0.45 0.22 0.23 0.054-0.141 -0.1 0.56 0.31 0.25 -0.023

0.93 0.76 0.42 0.78 0.35 -0.27-0.09 0.06 0.72 0.38 0.34 0.755

-0.187 -0.1 0.51 0.27 0.24 -0.008-2.475 -2.1 0.7 0.43 0.26 00.456 0.59 0.53 0.82 0.29 1.848

-1.503 -1.9 0.25 0.55 0.29 -1.0410.617 0.53 0.42 0.72 0.29 1.8390.073 0.06 0.45 0.67 0.21 -0.03-2.08 -2.1 0.41 0.76 0.34 -1.12

-1 -0.6 0.62 0.87 0.24 -1.2-0.212 -0.2 0.49 0.25 0.24 -0.0450.325 0.04 0.25 0.53 0.28 0.6670.124 0.1 0.43 0.74 0.31 -0.050.258 0.07 0.18 0.58 0.39 -0.519

-0.043 0 0.6 0.32 0.27 0.3790.619 0.46 0.43 0.78 0.35 1.8720.071 0.4 0.71 0.44 0.26 -0.6790.013 0.11 0.7 0.45 0.25 0.0080.311 0.16 0.34 0.64 0.29 0.7840.267 0.25 0.47 0.83 0.36 0.7750.119 0 0.22 0.48 0.26 0.5140.125 0.03 0.28 0.63 0.34 0.188

-0.381 -0.1 0.64 0.26 0.38 0.74-0.301 0 0.77 0.36 0.4 -0.261-1.41 -1.6 0.22 0.54 0.31 -1.52

-1.99 -2.2 0.35 0.71 0.35 -1.94-0.73 -0.8 0.36 0.76 0.4 -1.10.053 0.04 0.44 0.63 0.19 00.268 0.09 0.27 0.55 0.27 0.0140.059 0.02 0.37 0.6 0.22 -0.0670.216 0.03 0.31 0.6 0.28 0.444

-0.151 0 0.58 0.22 0.36 0.3680.272 0.12 0.37 0.61 0.23 0.063-1.63 -1.4 0.57 0.79 0.21 -1.71

-0.112 0.08 0.66 0.48 0.18 0.137-2.23 -2.1 0.51 0.74 0.23 -1.12

-0.201 -0.1 0.64 0.46 0.17 -0.456-0.219 -0.4 0.21 0.4 0.18 -0.5940.254 0.27 0.5 0.78 0.28 0.5540.341 0.11 0.35 0.59 0.24 0.1770.122 0.1 0.46 0.69 0.23 0.019

-0.166 -0.1 0.49 0.22 0.26 -0.0110.347 0.22 0.36 0.7 0.33 -0.217

-0.187 -0.2 0.48 0.24 0.24 -0.187-0.226 -0.1 0.57 0.22 0.35 -0.67

-1.5 -1.1 0.56 0.86 0.3 -1.08-2.39 -2.5 0.45 0.22 0.23 -1.810.456 0.22 0.32 0.67 0.34 0.0220.114 0.01 0.32 0.51 0.18 -0.547-2.02 -2.1 0.46 0.2 0.25 -0.9750.361 0.06 0.16 0.52 0.35 0.1840.448 0.51 0.52 0.78 0.25 0.6410.467 0.37 0.43 0.71 0.28 0.487-0.19 -0.2 0.44 0.13 0.3 0.0020.524 0.52 0.48 0.8 0.31 0.43-0.17 -0.2 0.43 0.16 0.26 -0.4840.279 0 0.23 0.46 0.22 1.2760.555 0.53 0.47 0.72 0.25 1.8390.12 0.03 0.32 0.57 0.25 -0.003

0.141 0.26 0.58 0.8 0.21 -0.02-0.153 0 0.62 0.38 0.23 -0.164-2.17 -2.2 0.4 0.7 0.3 -1.870.107 -0.2 0.26 0.61 0.35 -0.1370.118 0.1 0.47 0.72 0.25 0.115

-0.133 -0.1 0.49 0.12 0.36 0.090.252 0.08 0.3 0.58 0.28 0.1990.257 0.25 0.49 0.66 0.17 0.788-1.21 -1.2 0.46 0.81 0.35 -2.56

-0.062 -0.1 0.41 0.13 0.28 0.015-1.8 -2.1 0.26 0.44 0.17 -2.303

0.312 0.27 0.43 0.72 0.28 -0.0810.108 0.05 0.35 0.59 0.23 0.032

-0.281 -0.2 0.51 0.21 0.29 0.703-1.42 -1 0.64 0.87 0.23 -1.870.351 0.21 0.35 0.72 0.37 0.27

-0.2 -0.2 0.49 0.26 0.23 -0.0070.092 0.03 0.31 0.57 0.25 0.327

-0.383 -0.2 0.68 0.32 0.36 -0.117

-1.293 -1.3 0.46 0.75 0.28 -1.1130.228 0.13 0.41 0.65 0.23 -0.308-2.18 -2.2 0.45 0.71 0.26 -1.87

-0.119 -0.1 0.54 0.3 0.24 -0.041-0.45 -0.3 0.59 0.29 0.3 -0.590.163 0.15 0.47 0.85 0.37 0.209

-0.094 0 0.53 0.31 0.22 -0.090.411 0.66 0.58 0.83 0.24 0.4870.13 0.07 0.37 0.61 0.24 0.3

-0.187 0 0.63 0.39 0.23 -0.4820.112 0.1 0.49 0.69 0.2 -0.0350.238 0.52 0.56 0.81 0.24 0.7790.16 0.28 0.55 0.86 0.31 0.31

-0.186 -0.1 0.52 0.29 0.23 -0.0610.1 0.04 0.34 0.55 0.2 0.122

0.598 0.53 0.44 0.78 0.33 3.090.106 0.07 0.41 0.62 0.21 -0.210.202 0.03 0.28 0.51 0.22 0.017-1.01 -1 0.51 0.26 0.24 -0.7940.826 0.79 0.46 0.74 0.27 -2.8520.205 0.03 0.19 0.57 0.37 -0.0030.028 0 0.44 0.75 0.3 0.154-2.24 -1.9 0.53 0.81 0.28 -2.710.109 0.06 0.34 0.67 0.33 0.1670.195 0.14 0.41 0.72 0.31 0.195

-0.115 -0.1 0.49 0.12 0.36 0.6190.472 0.28 0.3 0.54 0.24 0.5640.163 0.1 0.36 0.63 0.27 0.411

-0.155 0 0.69 0.31 0.37 -0.2290.365 0.23 0.36 0.7 0.33 0.601

-0.316 -0.3 0.5 0.18 0.31 -0.0110.14 0.2 0.56 0.87 0.3 -0.128

0.192 0.15 0.42 0.66 0.23 -0.8840.156 0.12 0.4 0.78 0.37 0.271

-0.251 -0.1 0.62 0.35 0.27 0.1280.256 0.12 0.34 0.59 0.24 0.149

-0.153 -0.1 0.56 0.27 0.29 0.640.574 1.03 0.53 0.84 0.3 2.411

-0.177 -0.1 0.51 0.28 0.23 -0.2750.288 0.27 0.46 0.74 0.28 0.1170.129 0.12 0.47 0.68 0.21 0.4860.358 0.42 0.5 0.75 0.24 0.947

-0.509 -0.5 0.5 0.23 0.27 -0.77-0.236 -0.2 0.56 0.25 0.31 -0.073-1.39 -0.9 0.66 0.88 0.22 -0.630.262 0 0.2 0.45 0.25 0.6670.161 0.08 0.37 0.62 0.25 00.303 0.27 0.45 0.75 0.29 -0.039

-1.212 -1.2 0.47 0.81 0.33 -0.699-0.54 -0.3 0.66 0.27 0.38 -1.7

-0.469 -0.4 0.63 0.31 0.32 -0.465-0.99 -1.2 0.15 0.4 0.25 -1.33

-0.235 0 0.67 0.34 0.32 -0.64

0.179 0.14 0.44 0.64 0.2 0.3020.2 0.19 0.48 0.73 0.25 0.433

0.05 0 0.45 0.12 0.33 0.1410.498 0.33 0.37 0.71 0.33 6.643-0.15 0.06 0.83 0.56 0.26 -0.420.157 0.13 0.43 0.76 0.33 -0.078

-0.111 -0.2 0.4 0.16 0.24 0.266-0.453 -0.6 0.33 0.55 0.21 -0.365-0.087 -0.1 0.24 0.57 0.33 -0.9880.893 0.78 0.44 0.67 0.23 0.253-1.42 -1 0.59 0.91 0.32 -2.510.311 0.11 0.36 0.73 0.37 -0.213-0.08 -0.1 0.34 0.58 0.23 -0.12-1.53 -1.2 0.58 0.81 0.23 -1.21-1.5 -1.4 0.5 0.77 0.27 -1.52-0.8 -0.8 0.42 0.74 0.32 -0.65

-0.557 -0.4 0.59 0.27 0.32 -0.581-0.491 -0.4 0.67 0.31 0.36 -0.22-1.02 -0.9 0.52 0.85 0.32 -0.85

-1.273 -1.2 0.53 0.3 0.23 -1.2230.148 0.21 0.54 0.75 0.2 0.063

-0.167 -0.2 0.44 0.14 0.3 -0.153-0.033 0 0.52 0.27 0.24 0.5260.186 0.15 0.44 0.67 0.22 0.1320.24 0.34 0.52 0.72 0.19 0.6

-0.136 0 0.57 0.35 0.22 0.04-0.151 -0.1 0.5 0.26 0.23 -0.439-0.163 -0.1 0.69 0.32 0.36 0.059-1.55 -1.6 0.39 0.6 0.2 -0.70.427 0.42 0.49 0.8 0.3 0.3620.559 0.23 0.31 0.63 0.32 0.427-0.18 -0.1 0.5 0.28 0.21 -0.0350.61 0.4 0.35 0.69 0.33 0.23

-2.32 -2 0.55 0.83 0.27 -1.950.008 0 0.48 0.11 0.36 0.3590.072 0.03 0.37 0.61 0.23 -0.030.182 0.23 0.52 0.74 0.22 0.193

-0.244 0 0.76 0.43 0.32 -0.25-0.346 -0.2 0.62 0.24 0.37 -1.050.222 0.19 0.47 0.74 0.26 0.760.221 0.15 0.4 0.67 0.26 -0.016-0.95 -1.1 0.29 0.54 0.25 -0.680.153 0.17 0.51 0.73 0.22 0.6370.188 0.17 0.46 0.77 0.3 0.0390.383 0.35 0.45 0.69 0.23 1.537-1.14 -1.4 0.17 0.46 0.29 -1.36

-0.303 -0.4 0.42 0.11 0.31 -0.533-1.283 -1.1 0.61 0.36 0.25 -0.3590.351 0.32 0.47 0.71 0.24 0.215

-0.902 -0.9 0.51 0.13 0.37 -1.0460.116 0 0.27 0.44 0.16 0.8630.193 0 0.47 0.23 0.24 -0.6470.205 0.05 0.26 0.57 0.31 -0.013

-1.63 -1.4 0.59 0.79 0.19 -0.860.497 0.34 0.31 0.67 0.35 0.641

-0.077 0 0.64 0.47 0.17 0.090.328 0.49 0.54 0.8 0.26 0.7830.69 0.51 0.35 0.68 0.32 0.33

0.366 0.31 0.44 0.71 0.26 0.7160.083 0 0.28 0.55 0.26 0.026

-1.258 -1.2 0.51 0.29 0.22 -0.5970.336 0.55 0.55 0.81 0.26 0.851

-0.523 -0.3 0.56 0.76 0.19 -0.3650.159 0.06 0.31 0.6 0.28 0.194

-0.2 -0.1 0.63 0.28 0.34 0.640.073 0.11 0.53 0.73 0.2 0.0830.67 0.72 0.5 0.83 0.33 1.53

0.061 0.14 0.58 0.82 0.24 -0.3930.274 0.14 0.37 0.61 0.23 1.4990.131 0 0.44 0.12 0.32 1.36

-0.149 -0.1 0.54 0.32 0.22 -0.1480.457 0.22 0.36 0.62 0.26 1.537

-0.414 -0.3 0.56 0.29 0.26 -0.383-0.239 -0.1 0.62 0.31 0.3 0.7030.053 0.15 0.65 0.84 0.19 -0.2560.084 0.07 0.43 0.7 0.26 -0.030.107 0.03 0.25 0.61 0.35 -0.03-1.26 -1.1 0.52 0.82 0.3 -1.510.11 0.07 0.36 0.6 0.23 0.287

-0.196 0 0.86 0.5 0.36 -0.147-1.29 -0.8 0.62 0.9 0.28 -1.14

-0.095 0 0.65 0.41 0.23 0.041-0.082 0.06 0.69 0.47 0.22 -0.076

0.36 0.3 0.44 0.7 0.26 0.2150.041 0 0.38 0.55 0.17 -0.1980.149 0 0.25 0.5 0.25 0.768-2.13 -2.1 0.47 0.75 0.28 -2.520.428 0.93 0.55 0.83 0.27 -0.047-1.19 -0.8 0.66 0.87 0.21 -0.33

-0.169 -0.1 0.62 0.38 0.24 0.0020.294 0.53 0.88 0.53 0.35 0.30.097 0 0.24 0.5 0.26 0.327

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0.183 0.07 0.36 0.56 0.19 -0.007

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-0.105 -0.1 0.5 0.38 0.11 00.045 0.01 0.4 0.51 0.11 0.1

-0.044 1.17 0.95 0.85 0.1 -0.346-0.267 -0.1 0.67 0.46 0.21 0.45

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-0.004 0.13 0.68 0.58 0.09 0.503

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-0.098 0 0.56 0.39 0.17 0.3360.084 0.19 0.6 0.76 0.15 00.043 0.4 0.77 0.89 0.12 0.295

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-0.063 -0.2 0.34 0.17 0.17 -0.0190.005 0.13 0.7 0.55 0.14 0.2180.19 0.06 0.38 0.56 0.17 0

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-0.322 -0.3 0.48 0.37 0.11 -0.341

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-0.092 0 0.6 0.43 0.16 0.0390.049 0.22 0.59 0.75 0.15 0.4370.045 0.02 0.42 0.52 0.1 0.3580.007 0.04 0.57 0.65 0.07 0.0180.023 0.23 0.72 0.84 0.12 0.0360.042 0.14 0.64 0.82 0.17 -0.4030.038 -0.1 0.13 0.24 0.1 0.203

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-0.017 -0.1 0.34 0.17 0.17 -0.0270.033 0 0.34 0.5 0.15 -0.373-0.08 0 0.53 0.35 0.17 0.08

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-0.022 0.51 0.92 0.82 0.1 0.0810.154 0.23 0.55 0.69 0.13 0.6310.049 0.06 0.54 0.38 0.15 0.133

-0.077 0.21 0.62 0.69 0.07 -0.48-0.16 -0.3 0.41 0.24 0.16 -0.03

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-0.015 0.01 0.65 0.54 0.1 0.1050.047 0.01 0.41 0.51 0.1 0.0310.183 0 0.37 0.27 0.09 0.6080.041 -0.1 0.26 0.43 0.16 00.064 0 0.33 0.42 0.09 0.5240.129 0.12 0.45 0.63 0.18 0

-0.057 0 0.52 0.36 0.16 -0.160.023 0.01 0.48 0.58 0.1 -0.0380.052 0.03 0.4 0.58 0.17 -0.5420.046 0.03 0.43 0.6 0.16 -0.0170.007 -0.1 0.14 0.28 0.14 0.24

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-0.101 -0.1 0.5 0.36 0.14 0.2080.032 0 0.34 0.46 0.11 -0.143

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-0.043 0 0.53 0.39 0.13 -1.023-2.56 -2.2 0.65 0.75 0.1 -1.510.111 0.11 0.49 0.63 0.14 -0.349

-0.071 -0.1 0.49 0.31 0.17 -0.1420.337 0.31 0.46 0.57 0.1 2.369

-0.027 0 0.59 0.49 0.1 0.0930.061 0.2 0.58 0.67 0.09 0.0980.105 0.1 0.51 0.35 0.15 -0.415

-0.062 0.1 0.91 0.73 0.17 00.122 0.08 0.4 0.51 0.11 0.056-0.02 0.02 0.7 0.54 0.15 -0.118-1.18 -1.4 0.31 0.16 0.15 -1.410.081 0 0.34 0.5 0.15 -0.476

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-0.058 0 0.61 0.47 0.14 -0.1740.026 0 0.14 0.27 0.13 -0.076

-0.068 0 0.55 0.44 0.11 0.1060.032 0.15 0.62 0.73 0.1 -0.018

-0.071 0.05 0.75 0.58 0.16 0.4570.041 0.09 0.53 0.64 0.1 -0.1410.214 0.21 0.49 0.65 0.16 -0.193

-0.325 -0.4 0.38 0.27 0.11 -0.492-0.047 -0.2 0.32 0.21 0.1 -0.2740.045 0.12 0.59 0.68 0.09 0.035

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-0.208 0.29 0.89 0.72 0.17 0.6010.175 0.41 0.65 0.82 0.16 0.2010.011 0.09 0.71 0.53 0.17 0.1570.014 0.26 0.72 0.85 0.13 0.5630.114 0.35 0.65 0.8 0.14 0.365

-0.034 -0.2 0.34 0.2 0.13 0.1090.153 0 0.25 0.14 0.1 0.42

-0.425 0.17 0.75 0.89 0.13 0.3490.022 0.09 0.65 0.8 0.15 0.2220.137 0.87 0.72 0.87 0.15 -0.1120.097 0 0.1 0.26 0.15 -0.1910.111 0.61 0.74 0.9 0.15 0

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-0.082 -0.1 0.42 0.3 0.12 -0.0860.057 0.19 0.63 0.77 0.14 0.18-0.15 -0.1 0.57 0.38 0.18 -0.58

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-0.103 0.39 0.58 0.75 0.16 0-0.05 -0.2 0.27 0.09 0.18 0.08

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-0.397 -0.3 0.59 0.42 0.16 -0.5310.009 0 0.37 0.47 0.1 -0.0670.42 0.09 0.29 0.47 0.17 -0.51

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-0.026 0.12 0.93 0.81 0.11 0.005-0.102 0 0.51 0.36 0.14 1.0280.352 0 0.28 0.12 0.16 0.9890.042 0.16 0.64 0.74 0.09 0.31-2.72 -3.2 0.33 0.19 0.14 -3.460.023 0.08 0.55 0.69 0.14 0.1040.076 0.3 0.63 0.79 0.15 0.236

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-0.013 0.03 0.76 0.66 0.1 0.027-0.081 0.13 0.7 0.58 0.11 -0.085

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-0.033 -0.1 0.4 0.27 0.12 0.0570.041 0.01 0.43 0.52 0.08 0.4820.05 0.05 0.5 0.58 0.08 0.01

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-0.046 -0.3 0.11 0.16 0.04 -0.139-0.059 0 0.42 0.47 0.04 -0.4010.196 0.05 0.21 0.25 0.04 0.176

-0.015 0.17 0.74 0.78 0.04 -0.208-0.348 -0.3 0.54 0.48 0.06 -0.4260.009 -0.1 0.16 0.19 0.03 -0.103

-0.009 0 0.32 0.39 0.06 -0.231-0.258 0.4 0.78 0.84 0.05 -0.189-0.002 0.73 0.82 0.87 0.04 0.45-0.007 -0.1 0.17 0.22 0.04 0.202-0.002 0.04 0.79 0.73 0.05 -0.040.018 -0.4 0.1 0.07 0.03 0.358-0.02 0.15 0.95 0.89 0.05 -0.070.009 0 0.48 0.43 0.05 0.301

-0.068 0 0.58 0.52 0.05 -0.1940.2 0.1 0.39 0.34 0.04 0.192

-0.041 -0.1 0.37 0.42 0.05 0.251-0.519 -0.5 0.45 0.5 0.04 -0.49-1.84 -1.6 0.62 0.68 0.05 -1.51-1.46 -1.3 0.66 0.6 0.06 -1.010.012 0.78 0.93 0.97 0.03 0.218-0.03 0 0.36 0.41 0.04 0

-0.024 0 0.37 0.42 0.04 -0.433-0.017 0.05 0.72 0.67 0.05 -0.0060.003 0.05 0.58 0.63 0.05 0.054-0.01 0 0.47 0.52 0.05 0.120.018 -0.3 0.03 0.09 0.05 0.002-1.22 -0.9 0.64 0.69 0.05 -1.944

-0.546 0.33 0.87 0.93 0.05 0.4550.021 0 0.35 0.4 0.04 0.3540.064 0.04 0.45 0.48 0.03 0.051-0.01 0.06 0.8 0.77 0.03 0.090.19 0.28 0.63 0.68 0.05 0.16

-1.41 -1.3 0.54 0.6 0.06 -1.270.21 0.06 0.22 0.26 0.04 0

-0.008 -0.2 0.16 0.11 0.04 -0.0040.011 -0.1 0.07 0.11 0.04 0.006

-0.389 -0.2 0.55 0.6 0.04 0.836-0.267 -0.3 0.38 0.33 0.05 0.0860.472 0.37 0.35 0.41 0.06 0.0150.03 0.11 0.81 0.75 0.06 0

0.006 0.01 0.5 0.53 0.03 0.109-0.144 0.06 0.6 0.64 0.04 -0.06-2.68 -3.5 0.06 0.09 0.03 -3.96

-0.009 0 0.32 0.36 0.03 -0.14-0.017 0.5 0.96 0.92 0.03 -0.020.204 0.09 0.34 0.38 0.04 0.3950.027 0.34 0.88 0.92 0.04 0.04-0.12 -0.9 0.1 0.06 0.04 -0.434

-0.029 -0.4 0.07 0.03 0.04 0.059-0.028 -0.3 0.19 0.14 0.04 -0.805-0.007 -0.1 0.08 0.13 0.04 0.0060.013 -0.5 0.13 0.09 0.03 -0.1910.042 0.04 0.48 0.54 0.05 -0.709

-1.986 -2.6 0.23 0.18 0.04 -1.032-0.04 -0.6 0.24 0.18 0.05 0.2130.028 0.05 0.54 0.5 0.03 -0.417-0.03 0.24 0.68 0.72 0.04 -0.1870.249 0 0.19 0.23 0.04 0.605

-0.049 0.15 0.94 0.91 0.03 -0.0850.19 0.28 0.65 0.68 0.03 0.07

-1.21 -1 0.71 0.66 0.04 -1.72-0.003 0 0.16 0.13 0.02 0.03-0.01 0.37 0.7 0.74 0.03 -0.181

TF Expression level in Condition

Documents

GCN4 SM SIR1 Hughes00 10.2 6.27E-11 188 · SKN7_H2O2Losas3D_taf1-ts2Durant06 9.21 6.07E-10 163 UME6_H2O2Hiume6_del Bernstein_00_affydeletions9.2 6.18E-10 98 GCN4_SM swi1_rich_medium_experimentSudarsanam00