Future Of Diagnostic Imaging

A Look Into The Next Decade

?

(Part 3)

1980’s 1990’s 2000 - 2010

History of MR

Magnets &Base Systems

GradientSystems

“The Decade of RF”

• Fast Spin Echo

• Echo Planar ImagingExciteExcite

The Protons!The Protons!

FastEasy to UseRobustAnatomicalFunctional

RF

Magnet

‘02 ‘07

8-Channel 32-Channel MassivelyParallel

1.5T 3.0T HigherField Strengths

MR –More signal, capability, procedures

3.0T Comprehensive Neurosurgery

MR-Guided Intra-Operative Procedures While Maintaining Full OR Functionality.

Multi-Modality Image Guided Techniques.

Support Variety of Surgical Procedures.

State-of-the-Art Patient Transport Design.

Dual use of 3T Magnet:

Diagnostic imaging

MR Guided Surgery

20031998

1.5T8:00 minutes

1 mm resolution

3T 3.5 minutes

0.16 mm resolution

Never been seen before… new applications driving procedure volume

Noninvasive / minimally invasive therapy

Focused US Tumor AblationUSA Breast Cancer: 180K new cases per year

Hysterectomies: 170-300K / year for uterine fibroids

10 Sites globally are in Alpha testing of the technology

400+ patients successfully treated for Uterine Fibroid, Breast Fibroadenoma & Breast Cancer - negligible adverse events

Ablation of tumors is monitored in real time using temperature sensitive MR imaging

Business Case:> Potential patient population of 100,000+

annually.> Estimated Reimbursement rate: $7K-8K> A clinic can effectively perform 3-4

procedures/day

Why Is Digital Mammography Needed?Image Quality

• Film mammo has 20-35% missed cancers (screening)

• Film mammo has low positive predictive value

• Overexposed, underexposed films

• Film has poor contrast at skin line, chest wall

Productivity / Economic

• Film is expensive to buy, process, handle & store

• Interventional procedures

• Only one copy of film – cannot be transmitted

Film Screen Mammography Reduces Breast Cancer Mortality by 20-40%, But There is Significant Room for Improvement

Computer Aided Diagnosis

Tomosynthesis 3D

Contrast Mammography

Delivered

Delivered

Limitation

Interpretation variability

Overlapping tissue

Lesion 3D features

Lesion not x-rayradio-opaque

Image quality and QC

Solution

CAD

3D

3D

ContrastU/S

FFDM

FFDM Advanced Apps Target Mammography’s Key Limitations

Delivered

FFDM/US Fusion

Premium View

TACT® 3D