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FROM VACCINE
TO
VACCINATION
Prof. Do Sy Hien
Former Manager of EPI, Vietnam
WHY TO PROMOTE THE VACCINATION
• VACCINES ARE BIOLOGICAL PRODUCTS ONLY, BUT VACCINATION PROTECT HUMAN HEALTH
• COUNTRIES HAVE TO PROMOTE VACCINATION BY IMPLEMENTING OF EPI
EPI ACHIVEMENT IN
VIETNAM
DISEASE NO OF
CASES/DEATH
1984
NO OF CASES/DEATH
2016
CASES DEATH CASES DEATH
POLIO 1,149 44 0 (ERA. BY 2000)
0
DIPTHERIA 2.357 226 13 3
PERTUSSIS 44.926 32 267 2
NEONATAL
TETANOUS
1.331 250 32(ELI BY 2005)
17
MEALSES 82.899 303 46 0
TOTAL 132.662 855 358 22
SELECTION OF VACCINE
INTO EPI
• DISEASE PRESSURE (MORBILITY AND
MOTABILITY, ECONOMICAL BURDEN).
• POSSIBILITY (VACCIN SUPPLY, FINANCIAL
CAPABILITY, LOGISTIC, HEALTHCARE
HUMANITY ..)
• SUSTAINABILITY
• PRIORITY TARGETS OF THE PERIOD
• COMMUNITY ADVOCACY
EPI VACCINES IN
VIETNAM
• BEFORE 1997: VIETNAM PROVIDED VACCINATION FOR 6 COMMON DISEASES (TUBERCULOSIS, DIPHTHERIA. PERTUSSIS, TETANUS. POLIO. MEALSE), VIETNAM HAS PRODUCED DPT. BCG AND POLIO
• FROM 1997, VIETNAM APPROVED TO IMPLEMENT 4 ADDITIONAl VACCINE IN EPI: HEPATITIS B, JAPANESE ENCEPHALITIS, CHOLERA, AND TYPHOI. THIS TIME VIETNAM HAS PRODUCED VACCINE HepB, CHOLERA AND JE
• 2010 Hib (QUINVAXEM) DONATED BY GAVI
• 2014 RUBELLA (MR)
ADDITIONAL VACCINES
CONSIDRATION IN NEAR FUTURE
• VIETNAM PROVIDE 12 VACCINES IN EPI IN CURRENT
TIME.
• A LOT OF VACCINES NEEDED FOR CHILDREN,
ADOLESCENTS AND ADULT : ROTA, HPV, SEASON
FLU, PNEUMOCOCUS, MENINGITIS..
IN THE NEAR FUTURE VIETNAM SHOULD CONSIDER
DEPLOYMENT OF ROTA (LOCAL), SEASONAL FLU
VACCINES (LOCAL) AND PNEUMOCOCUS VACCINE
MAINTAIN HIGH COVERAGE VACCINATION IN EPI
• NEEDS:
• HIGH ADVOCACY OF THE COMMUNITY
• THE CONCERN OF THE AUTHORITIES
• THE HEALTH SYSTEM IS STRONG ENOUGH
BARRIER OF MAINTAIN
THE EPI COVERAGE
• AEFI
• THE DECLINE IN COMMUNITY TRUST
• PRESSURE OF THE MASS MEDIA
. DIMINISHED THE CONCERN OF THE
AUTHORITIES AT ALL LEVELS
• PRESSURE OF AEFI WITH HEALTHCARE
STAFF
DPT COVERAGE
4,1
3,9
3,4
2,9
1,6
0,90,8
0,7 0,73
0,24 0,23 0,23 0,2 0,2 0,170,11 0,15
0,210,13 0,13
0,06 0,04 0,03 0,04 0,02 0,01 0,01 0,01 0,01 0,01 0,01 0,01 0,01
70
8887
54
70
83
87 88 8891
94 93 9495
94
93
96 96
75
99
96
98
97
96 96 97
93
9596
83
9597 96
0
20
40
60
80
100
0
1
2
3
4
5
TL
mắc B
ạch
hầu
/100.0
00 d
ân
Năm
TL
tiêm
DP
T3
/DP
T-V
GB
-Hib
3 (%
)
TL mắc/100.000 dân TL DPT3/DPT-VGB-Hib3 (%)
SOLUTION
• STRENGTHEN VACCINATION SAFETY (VACCINE QUALITY, PRESERVATION, VACCINE TRANSPORTATION, IMMUNIZATION PRACTICE, COUNSELLING VACCINATION, FOLLOW UP AFTER VACCINATION, MONITORING AND SUPERVISION
• QUICKLY TO IDENTIFY AEFI CASES AND RESPONSE
• TAKE THE ADVANTAGE OF THE SUPPORT FROM MASS MEDIA AND THE AUTHORITIES AT ALL LEVELS
• HAVING DIRECTIONS TO DOMESTIC MANUFACTURERS IN THE PRODUCTION OF VACCINE FOR THE FUTURE
APPROPRIATE IN LINE WITH
THE EPIDEMIOLOGY CHANGE
OF VACCINATED DISEASES
• CHANGE OF THE EPI DISEASES EPIDEMIOLOGY
• IMMUNE FLAW APPEAR IN THE COMMUNITY TO FACILITATE OUTBREAKS SUCH AS MEALSES, DIPTHERIA, PERTUSSI
• SOLUTION
• DEVELOP A QUALITY EPIDEMIOLOGICAL SURVEILLANCE SYSTEM
• RESEARCH AND ORIENTATION ARE NEEDED FOR BOOTSER AND ADDITIONAL DOSAGE,OR IMMUNIZATION CAMPAIGN FOR HIGH RISK OBJECTS
• SELECT THE APPROPRIATE VACCINES
MEALSE OUTBREAK
2009, 2014
150,5
138,2
112,8
48,9
36,734,6
13,2 12,1
17,3 17,3 16,7
8,6 07 8,8
15,517,8
21,3
15,7
8,5
2,90,3 0,5 2,4
0 0,4
9,1
030,9 0,6 1,27
17,7
0,3 0,054
19
39
42
66
89
87 8890
93
96 9596
96
96
94
9798
96
93
9799
96
86
96 97 9896 96
96 97 97 98
0
20
40
60
80
100
0
40
80
120
160
TL
mắc/1
.000.0
00 d
ân
TL
tiêm
VX
sở
i (%)
TL mắc/100.000 dân TL tiêm VX Sởi (%)
CDT.Quốc
CD NC cao
Mũi 2 (6 tuổi)2006-2010
CD NC cao
CDT.Quốc
Mũi 218 th
LOCAL VACCINE
PRODUCTION
• VACCINE SUPPLY IN TIME
• AT PRESENT, VIETNAM PRODUCED MORE
THAN 10 VACCINES: BCG, DPT, POLIO,
MEALSE, MR, JE, Hep B, CHOLERA, TYPHOID,
FLU H1N1, FLU H5N2
• VIETNAM STEP BY STEP TRY TO PRODUCE
OTHER VACCINES: COMBINATION 5 IN 1
(DaPTHepBHib), biOPV, IPV, conjungate
Typhoid…
Thank you
