Franklin D. West Associate Professor Regenerative ......F. D. West Curriculum Vita 1 CURRICULUM VITAE Franklin D. West Associate Professor Regenerative Bioscience Center 425 River

F. D. West Curriculum Vita 1

CURRICULUM VITAE

Franklin D. West Associate Professor

Regenerative Bioscience Center

425 River Road Room 316

Athens, GA 30602 (706) 542-0988 [email protected]

www.westlaboratory.org

RESEARCH INTERESTS My research interests are in the field of stem cell biology and regenerative medicine with an emphasis in stem cell therapies for stroke and traumatic brain injury. EDUCATION

Doctor of Philosophy in Animal Science 2004-2008 University of Georgia Athens, GA Emphasis in Stem Cell Biology and Regenerative Medicine Dr. Steven L. Stice (Advisor) Graduate Recruitment Opportunities (GRO) Research Scholar Bachelors of Science in Biology 2000-2003 Morehouse College Atlanta, GA Emphasis in Environmental Sciences Magna Cum Laude David and Lucile Packard Research Fellow (Packard Foundation) MARC U*STAR Research Fellow (National Science Foundation) ARC Scholar (ARCS Foundation) Princeton REU Scholar (National Science Foundation) Cornell REU Scholar (National Science Foundation)

ACADEMIC AND PROFESSIONAL POSITIONS 2018-Current University of Georgia Research University of Georgia

Foundation Board Member 2018-Current Development 1 Study National Institutes of

Section Member Health 2017-Current Stem Cell Therapies as an

Emerging Paradigm in Stroke Consortium Member

2016-Current Associate Professor University of Georgia


2014-Current Regenerative Bioscience Center University of Georgia Undergraduate Research Program Leader

2013-Current Regenerative Engineering & Emory University, Medicine Research Center Georgia Institute of Executive Committee Member Technology and University of Georgia

2010-Current Regenerative Bioscience Center University of Georgia Executive Committee Member

2010-2016 Assistant Professor University of Georgia 2009- 2010 Assistant Research Scientist University of Georgia 2007-2008 Product Quality Control Scientist ArunA Biomedical

REFEREED PUBLICATIONS Published

1. “Identification of predictive MRI and functional biomarkers in a pediatric piglet traumatic brain injury model.” Hongzhi Wang, Emily W. Baker, Abhyuday Mandal, Ramana M. Pidaparti, Franklin D. West§ and Holly A. Kinder§. Accepted Dec. 2019 in Neural Regeneration Research. §=Co-corresponding Authors

2. “Large animal ischemic stroke models: replicating human stroke pathophysiology.” Erin E. Kaiser and Franklin D. West. Accepted Nov. 2019 in Neural Regeneration Research.

3. “Neural stem cell extracellular vesicles disrupt midline shift predictive outcomes in porcine ischemic stroke model.” Samantha E. Spellicy, Erin E. Kaiser, Michael M. Bowler, Brian J. Jurgielewicz, Robin L. Webb, Franklin D. West, Steven L. Stice. Accepted in Translational Stroke Research. [Epub ahead of print 2019 Dec].

4. “Tropism of Newcastle disease virus strains for chicken neurons and glia.” Salman L. Butt, Veridiana MBD de Moura, Leonardo Susta, Patti J. Miller, Jessica M. Hutcheson, Stivalis Cardenas-Garcia, Corrie C. Brown, Franklin D. West, Claudio L. Afonso, James B. Stanton. BMC Veterinary Research. 2019 Sep 4;15(1):317.

5. “Stirred Suspension Bioreactor Culture of Porcine Induced Pluripotent Stem Cells.” Kyle Burrell, Rkia Dardari, Taylor Goldsmith, Derek Toms, Daniel A.F. Villagomez, W. Allan King, Mark Ungrin, Franklin D. West, Ina Dobrinski. Stem Cells and Development. [Epub ahead of print 2019 July]. 2019 Sep 15;28(18):1264-1275.

6. “Pig Brains Have Homologous Resting State Networks with Human Brains.” Gregory Simchick*, Alice Shen*, Brandon Campbell, Hea Jin Park, Franklin D. West§, and Qun Zhao§. Brain Connectivity. [Epub ahead of print 2019 May]. 2019 Sep;9(7):566-579. *= Co-first Authors; §=Co-corresponding Authors

7. “Controlled cortical impact leads to cognitive and motor function deficits that correspond to cellular pathology in a piglet traumatic brain injury model.” Holly A. Kinder, Emily W. Baker, Elizabeth W. Howerth, Kylee Jo J. Duberstein and Franklin D. West. Journal of Neurotrauma. [Epub ahead of print 2019 May].2019 Oct 1;36(19):2810-2826.

8. “Traumatic Brain Injury Results in Dynamic Brain Structure Changes Leading to Acute and Chronic Motor Function Deficits in a Pediatric Piglet Model.” Holly A. Kinder*, Emily W. Baker*, Silun Wang, Candace C. Fleischer, Elizabeth W. Howerth, Kylee Jo J.


Duberstein, Hui Mao, Simon R. Platt, and Franklin D. West. Journal of Neurotrauma. [Epub ahead of print 2019 May]. 2019 Oct 15;36(20):2930-2942. *= Co-first Authors

9. “mRNA reprogramming of T8993G Leigh's syndrome fibroblast cells to create induced pluripotent stem cell models for mitochondrial disorders.” Harrison E. Grace, Patrick Galdun III, Edward J. Lesnefsky, Franklin D. West, Shilpa Iyer. Stem Cells and Development. [Epub ahead of print 2019 April]. 2019 Jul 1;28(13):846-859.

10. “Neural Stem Cell Therapy for Stroke: A Multi-Mechanistic Approach to Restoring Neurological Function.” Emily W. Baker, Holly A. Kinder, Franklin D. West. Brain and Behavior. [Epub ahead of print 2019 Feb]. 2019 Mar;9(3):e01214.

11. “Isolation and Differentiation of Mesenchymal Stem Cells from Broiler Chicken Compact Bones.” Roshan Adhikari, Chongxiao Chen, Elizabeth Waters, Franklin West and Woo Kyun Kim. Frontiers in Physiology. 2019 Jan 22;9:1892.

12. “The Pig as a Preclinical TBI Model: Current Models, Functional Outcome Measures, and Translational Detection Strategies.” Holly A. Kinder, Emily W. Baker, Franklin D. West. Neural Regeneration Research. [Epub ahead of print 2018 Dec]. 2019 Mar;14(3):413-424.

13. “Scaled traumatic brain injury results in unique metabolomic signatures between gray matter, white matter, and serum in a piglet model.” Emily W. Baker, W. Matthew Henderson, Holly A. Kinder, Jessica M. Hutcheson, and Franklin D. West. PLOS ONE. 2018 Oct 31;13(10):e0206481.

14. “Controlled Cortical Impact Severity Results in Graded Cellular, Tissue and Functional Responses in a Piglet Traumatic Brain Injury Model.” Emily W. Baker*, Holly A. Kinder*, Jessica M. Hutcheson, Kylee Jo J. Duberstein, Simon R. Platt, Elizabeth W. Howerth, Franklin D. West. Journal of Neurotrauma. [Epub ahead of print 2018 Jun]. 2019 Jan 1;36(1):61-73. *= Co-first Authors

15. “LiF@SiO2 nanoparticles for controlled lithium release and osteoarthritis therapy.” Trever Todd, Zhenhui Lu, Benjamin Cline, Jinmin Zhao, Weizhong Zhang, Hongmin Chen, Anil Kumar, Wen Jiang, Franklin West, Samuel Franklin, Li Zheng, and Jin Xie. Nano Research. [Epub ahead of print 2018 Apr]. 2018. Oct;11(10): 5751-5760.

16. “Human neural stem cell extracellular vesicles improve recovery in a porcine model of ischemic stroke.” Robin L. Webb*, Erin E. Kaiser*, Brian J. Jurgielewicz, Samantha E. Spellicy, Shelley L. Scoville, Tyler A. Thompson, Raymond L. Swetenburg, David C. Hess, Franklin D. West and Steve L. Stice. Stroke. 2018 May;49(5):1248-1256. *= Co-first Authors

17. “Human iNPC therapy leads to improvement in functional neurologic outcomes in a pig ischemic stroke model.” Vivian W. Lau, Simon R. Platt, Harrison E. Grace, Emily W. Baker, and Franklin D. West. Brain and Behavior. [Epub ahead of print 2018 Apr]. 2018 Apr 18;8(5).

18. “Induced Pluripotent Stem Cell-Derived Neural Stem Cell Therapy Enhances Recovery in an Ischemic Stroke Pig Model.” Emily W. Baker, Simon R. Platt, Vivian W. Lau, Harrison E. Grace, Shannon P. Holmes, Liya Wang, Kylee Jo Duberstein, Elizabeth W. Howerth, Holly A. Kinder, Steve L. Stice, David C. Hess, Hui Mao, and Franklin D. West. Scientific Reports. [Epub ahead of print 2017 Mar 7]. 2017 Aug 30;7(1):10075.

19. “Pig Induced Pluripotent Stem Cell Derived Neural Rosettes Parallel Human Differentiation into Sensory Neural Subtypes.” Robin L. Webb, Amalia Gallegos-Cardenas, Colette N. Miller, Nicholas J. Solomotis, Hong-Xiang Liu, Franklin D. West and Steve L. Stice. Cellular Reprogramming. [Epub ahead of print 2017 Mar 7]. 2017


Apr;19(2):88-94. 20. “Derivation of Chicken Induced Pluripotent Stem Cells Partially Resistant to Newcastle

Disease Virus-Induced Lysis Through Multiple Rounds of Infection.” Leonardo Susta, Ying He, Jessica H. McCabe, Yangqing Lu, Franklin D. West, Steven L. Stice, Ping Yu, Claudio L. Afonso. Virology Journal. 2016 Dec 5;13(1):205.

21. “Development, characterization and optimization of a new suspension chicken-induced pluripotent cell line for the production of Newcastle disease vaccine.” Ismaila Shittu, Ziying Zhu, Yangqing Lu, Jessica M. Hutcheson, Steven L Stice, Franklin D West, Meritxell Donadeu, Baptiste Dungu, Aly M Fadly, Guillermo Zavala, Nola Ferguson-Noel and Claudio L Afonso. Biologicals. [Epub ahead of print 2015 Nov 13]. 2016 Jan;44(1):24-32.

22. “Episomal Vector Restores LDLR Function in Monogenic Deficient iPSC-Derived Hepatocytes.” Venkat M. Ramakrishnan*, Jeong-Yeh Yang*, Braden R. Bocard, Kevin T. Tien, John G. Maijub, Patrick O. Burchell, Stuart K. Williams, Marvin E. Morris, James B. Hoying, Richard Wade-Martins, Franklin D. West, and Nolan L. Boyd. Scientific Reports. 2015 Aug 26;5:13231. *= Co-first Authors

23. “Delayed Newcastle Disease Virus Replication using RNA Interference to Target the Nucleoprotein.” Jessica Hutcheson, Leonardo Susta, Steven L Stice, Claudio L Afonso and Franklin D West. Biologicals. [Epub ahead of print 2015 June 4]. 2015 Jul;43(4):274-80.

24. “Pig Induced Pluripotent Stem Cells Derived Neural Rosette Developmentally Mimic Human Pluripotent Stem Cells Neural Differentiation.” Amalia Gallegos-Cárdenas, Robin L Webb, Erin T Jordan, Rachel C West, Jeong-Yeh Yang, Kai Wang, Franklin D West and Steven L Stice. Stem Cells and Development. [Epub ahead of print 2015 March 31]. 2015 Aug 15;24(16):1901-11.

25. “Chimeric Non-Viral Minicircle Generation of Induced Pluripotent Stem Cells Compatible with Production of Chimeric Chickens.” Ping Yu, Yangqing Lu, Brian J. Jordan4, Yubing Liu, Jeong-Yeh Yang, Jessica M. Hutcheson, Christina L. Ethridge, Jennifer L. Mumaw, Holly A. Kinder, Robert B. Beckstead, Steven L. Stice and Franklin D. West. Cellular Reprogramming. [Epub ahead of print 2014 August 1]. 2014 Oct;16(5):366-78.

26. “Induced Pluripotency in Chicken Embryonic Fibroblast Results in a Germ Cell Fate.” Yangqing Lu, Franklin D. West, Brian J. Jordan, Erin T. Jordan, Rachel West, Ping Yu, Ying He, Miguel A. Barrios, Ziying Zhu, James N. Petitte, Robert B. Beckstead, Steven L. Stice. Stem Cells and Development (Journal Cover Image). [Epub ahead of print 2014 April 10]. 2014 Aug 1;23(15):1755-64.

27. “Development and Characterization of a Yucatan Miniature Biomedical Pig Permanent Middle Cerebral Artery Occlusion Stroke Model. ” Simon R Platt, Shannon P Holmes, Elizabeth W Howerth, Kylee Jo J Duberstein, C Robert Dove, Holly A Kinder, Emily L Wyatt, Amie V Linville, Vivian W Lau, Steven L Stice, William D Hill, David C Hess, Franklin D West. Experimental & Translational Stroke Medicine. 2014 Mar 23;6(1):5.

28. “Culture of Pig Induced Pluripotent Stem Cells Without Direct Feeder Contact In Serum Free Media.” Jeong-Yeh Yang, Yubing Liu, Ping Yu, Yangqing Lu, Jessica M. Hutcheson, Vivian W. Lau, Xiangping Li, C. Robert Dove, Steven L. Stice and Franklin D. West. Journal of Stem Cell Research & Therapy. [Epub ahead of print 2014 February 22].


29. “Comparative Gene Expression Signature of Pig, Human and Mouse Induced Pluripotent Stem Cell Lines Reveals Insight into Pig Pluripotency Gene Networks.” Yajun Liu, Yangyang Ma, Jeong-Yeh Yang, De Cheng, Xiaopeng Liu, Xiaoling Ma, Franklin D. West, Huayan Wang. Stem Cell Research. [Epub ahead of print 2013 December 13]. 2014 Apr;10(2):162-76.

30. “Gait Analysis in a Pre- and Post-Ischemic Stroke Biomedical Pig Model.” Kylee Jo Duberstein, Simon R. Platt, Shannon P. Holmes, C. Robert Dove, Elizabeth W. Howerth, Marc Kent, Steven L. Stice, William D. Hill, David C. Hess and Franklin D. West. Physiology & Behavior. [Epub ahead of print 2013 November 25]. 2014 Feb 10;125:8-16.

31. “α-1,3-Galactosyltransferase Knockout Pig Induced Pluripotent Stem Cells: A Cell Source for the Production of Xenotransplant Pig.” Yubing Liu, Jeong Yeh Yang, Yangqing Lu, Ping Yu, C. Robert Dove, Jessica M. Hutcheson, Jennifer L. Mumaw, Steven L. Stice and Franklin D. West. Cellular Reprogramming. [Epub ahead of print 2013 Febuary 12]. 2013 Apr; 15 (2):107-16.

32. “In Vitro Derived Gametes from Stem Cells.” Franklin D. West, Reza Shirazi, Pezhman Mardanpour, Servet Ozcan, Gokcen Dinc, Dewey H. Hodges, Hamid Reza Soleimanpour-Lichaei and Karim Nayernia. Seminars in Reproductive Medicine. [Epub ahead of print 2013 January 17]. 2013 Jan; 31 (1):33-38.

33. “SSEA4 Positive Pig Induced Pluripotent Stem Cells Are Primed for Differentiation into Neural Cells.” Jeong-Yeh Yang, Jennifer L. Mumaw, Yubing Liu, Steve L. Stice and Franklin D. West. Cell Transplantation. [Epub ahead of print 2012 October 03]. 2013; 22 (6):945-59.

34. “Livestock Induced Pluripotent Stem Cells.” Yangqing Lu, Jennifer L. Mumaw, Franklin D. West, and Steven L. Stice. Reproduction in Domestic Animals. [Epub ahead of print 2012 July 25]. 2012 Aug; 47 Suppl 4:72-6.

35. “Comparative epigenomic annotation of regulatory DNA.” Shu Xiao, Dan Xie, Xiaoyi Cao, Pengfei Yu, Xiaoyun Xing, Chieh-Chun Chen, Mingchao Xie, Franklin D. West, Harris Lewin, Ting Wang, Sheng Zhong. Cell. 2012 Jun 8; 149 (6):1381-92.

36. “Metabolomic Response of Human Embryonic Stem Cell Derived Germ-like Cells after Exposure to Steroid Hormones.” Franklin D. West, W. Matthew Henderson, Ping Yu, Jeong-Yeh Yang, Steven L. Stice, and Mary Alice Smith. Toxicological Sciences (Journal Cover Image August 2014 edition). [Epub ahead of print 2012 May 30]. 2012 Sep; 129 (1):9-20.

37. “Rapid heterotrophic ossification with cryopreserved poly (ethylene glycol) microencapsulated BMP2 expressing MSCs.” Jennifer Mumaw, Erin Jordan, Corinne Sonnet, Ronke Olabisi, Elizabeth A. Olmsted-Davis, Alan R. Davis, J. L. West, Franklin West, Yangqing Lu and Steven L. Stice. International Journal of Biomaterials. [Epub ahead of print 2012 Feb 8]. 2012; 2012:861794. 2012; 2012:861794.

38. “Avian Induced Pluripotent Stem Cells Generate Live Quail-Chicken Chimeras and Undergo Advanced In Vitro Differentiation.” Yangqing Lu, Franklin D. West, Brian J. Jordan, Jennifer L. Mumaw, Erin T. Jordan, Amalia Gallegos-Cardenas, Robert B. Beckstead, Steven L. Stice. Stem Cells and Development (Journal Cover Image). [Epub ahead of print 2011 Oct 4]. 2012 Feb 10; 21(3):394-403.


39. “Progress towards Generating Informative Porcine Biomedical Models Using Induced Pluripotent Stem Cells.” Franklin West and Steve Stice. Annals of the New York Academy of Sciences. 2011 Dec; 1245 (1):21-3.

40. “Chimeric Pigs Produced from Induced Pluripotent Stem Cells Demonstrate Germline Transmission and No Evidence of Tumor Formation.” Franklin D. West, Elizabeth W. Uhl, Yubing Liu, Heather Stowe, Yangqing Lu, Ping Yu, Amalia Gallegos Cardenas, Scott L. Pratt and Steven L. Stice. Stem Cells. [Epub ahead of print 2011 Sep 27]. 2011 Oct 29 (10): 1640-1643.

41. “Membrane proteomic signatures of karyotypically normal and abnormal human embryonic stem cell lines and derivatives.” Brian A. Gerwe*, Peggi M. Angel*, Franklin D. West, Kowser Hasneen, Amber Young Ron Orlando and Steven L. Stice. Proteomics. [Epub ahead of print 2011 May 20]. 2011 Jun; 11(12):2515-27. *= Co-first Authors

42. “Human Haploid Cells Differentiated from Meiotic Competent Clonal Germ Cell Lines that Originated from Embryonic Stem Cells.” F. D. West, J. L. Mumaw, A. Gallegos-Cardenas, A. Young and S. L. Stice. Stem Cells and Development. [Epub ahead of print 2010 Oct 7]. 2011 Jun; 20 (6):1079-88.

43. "Glial Cell-line Derived Neurotrophic Factor Enhances in vitro Differentiation of Mid/hindbrain Neural Progenitor Cells to Dopaminergic-like Neurons." A. Young, K. Assey, C. Sturkie, F. D. West, D. Machacek, S. Stice. Journal of Neuroscience Research. 2010 Nov 15; 88 (15): 3222-32.

44. “Porcine Induced Pluripotent Stem Cells Produce Chimeric Offspring.” F. D. West, S. L. Terlouw, D. Kwon, J. L. Mumaw, S. K. Dhara, K. Hasneen, J. R. Dobrinsky and S. L. Stice. Stem Cells and Development (Journal Cover Image). [Epub ahead of print 2010 Apr 9]. 2010 Aug 19 (8): 1211-20.

45. “Lineage-Specific Promoter DNA Methylation Patterns Segregate Adult Progenitor Cell Types.” A. L. Sorensen, S. Timoskainen, F. D. West, K. Vekterude, A. C. Boquest, L. Ahrlund-Richter, S. L. Stice and P. Collas. Stem Cells and Development. [Epub ahead of print 2009 Nov 3]. 2010 Aug 19 (8): 1257-66.

46. “KIT ligand and bone morphogenetic protein signaling enhances human embryonic stem cell to germ-like cell differentiation.” F. D. West, M. I. Roche-Rios, S. Abraham, R. R. Rao, M. S. Natrajan, Bacanamwo, M and S. L. Stice. Human Reproduction. [Epub ahead of print 2009 Oct 19]. 2010 Jan 25 (1): 168-78.

47. “Human Embryonic Stem Cell Derived Mesoderm-like Epithelium Transitions to Mesenchymal Progenitor Cells.” N.L. Boyd, K.R. Robbins, S.K. Dhara, F.D. West, S.L. Stice. Tissue Engineering. 2009 Aug 15 (8): 1897-907.

48. “Enrichment and Differentiation of Human Germ-like Cells Mediated by Feeder Cells and Basic Fibroblast Growth Factor Signaling.” Franklin D. West, David W. Machacek, Nolan L. Boyd, Kurinji Pandiyan, Kelly R. Robbins, and Steven L. Stice. Stem Cells. 2008 Nov 26 (11): 2768-76 [Epub ahead of print 2008 Aug 21].

49. “BMP4 Promotes Formation of Primitive Vascular Networks in Human Embryonic Stem Cell Derived Embryoid Bodies.” N.L. Boyd, S.K. Dhara, R. Rekaya, E.A. Godbey, K. Hasneen, R.R. Rao, F.D. West III, B.A. Gerwe, S.L. Stice. Experimental Biology and Medicine. 2007 Jun 232:833-43.


50. “Uniform adherent neural progenitor populations from rhesus embryonic stem cells.” Deanne Tibbitts, Raj R. Rao, Soojung Shin, Franklin D. West and Steven L. Stice. Stem Cells and Development. 2006 Apr. 15: 200-208.

BOOK CHAPTERS

1. “Induced Pluripotent Stem Cell Derived Neural Cell Types In Treatment of Stroke. Vivian W. Lau DVM, Simon R. Platt, Steven L. Stice and Franklin D. West. Cell Therapy for Brain Injury. Springer. 2015.

2. “Induced Pluripotent Stem Cells as a Cell-based Therapeutic in Stroke.” David C. Hess, Nasir Fakhri, Franklin D. West. Cell Therapy for Brain Injury. Springer. 2015.

3. “Generation of chimeras from porcine induced pluripotent stem cells.” Franklin D. West, Steve L. Terlouw, John R. Dobrinsky, Yangqing Lu, Erin T. Jordan and Steven L. Stice. Cell Reprogramming: Methods and Protocols (Methods in Molecular Biology). Humana Press+ Springer. 2015.

4. “Generation of avian induced pluripotent stem cells.” Yangqing Lu, Franklin D West, Brian J. Jordan, Robert B. Beckstead, Erin T. Jordan, Steven L Stice. Cell Reprogramming: Methods and Protocols (Methods in Molecular Biology). Humana Press+ Springer. 2015.

NON-REFEREED PUBLICATIONS (Semi-Technical/Lay Publications)

1. F. D. West and S. L. Stice. Understanding the Biology and Underlying Mechanisms of Gamete Development, Fertilization and Embryogenisis. Refine Methods for Production of Genetically Modified Animals to Improve Livestock Productivity Efficiency. Germ Cell and Embryo Development and Manipulation for the Improvement of Livestock. W-1171 Multistate Research Committee Technical Report. 2009 Jan. Pg. 26-27.

2. S. L. Stice, F. D. West and Y. Lu. Disease Resistant Livestock. Germ Cell and Embryo Development and Manipulation for the Improvement of Livestock. W-2171 Multi-State Research Committee Technical Report. 2009 Jan. Pg. 36-38.

FUNDING Current:

1. National Institutes of Health. 1R01NS093314-01 Combined Nanoparticle and Neural Stem Cell Therapies in a Pig Model of Stroke. 2015-2020, Role: PI.

2. Department of Defense. Patient-specific human induced pluripotent stem cells for mitochondrial diseases. 2016-2019, Role: Co-I.

3. United States Department of Agriculture. 20S oxysterol enhances osteogenesis and myogenesis and inhibits adipogenesis. 2017-2020, Role: Co-I.

4. LipoSeuticals. The effect of a LipoSeutical on neurofunction. 2019-2020, Role: Co-I. 5. Department of the Army. Heart-on-Chip for Drug Efficacy Testing for Mitochondrial

Diseases. 2020-2021, Role: Co-I.

Completed: 1. National Institutes of Health. 1R43NS103596-0. Human Neural Cell Exosomes as a

therapeutic treatment for stroke. 2017-2018, Role: Co-I.


2. Science and Engineering Research Board (SERB) and Indo-US Science and Technology Forum (IUSSTF). SERB Indo-US Postdoctoral Fellowship. 2016. 2016-2017, Role: Co-I/Mentor.

3. ArunA Biomedical. Human Stem Cell-derived Exosomes for Preclinical Stroke II. 2016-2017, Role: PI.

4. ArunA Biomedical. Human Stem Cell-derived Exosomes for Preclinical Stroke. 2016-2017, Role: PI.

5. American Veterinary Medical Association. Opportunity Research Scholarship. 2017, Role: Co-PI/Mentor.

6. Zoetis. MSCs Enhanced Muscle and Bone Development in Chickens. 2014-2016, Role: PI.

7. Zoetis. Isolation and Differentiation of Chicken Embryonic Stem Cells into Muscle Cells. 2014-2016, Role: PI.

8. REM: Regenerative Engineering & Medicine Research Center (Emory University, Georgia Institute of Technology and University of Georgia Research Initiative). Longitudinal MRI and MRS Assessment of iPSC Neural Stem Cell Treatment in White Brain Matter. 2013-2015, Role: Co-PI.

9. National Institutes of Health. R56HL121392-01A1: A high-density lipoprotein-based theranostic nanoparticle platform for atherosclerosis. 2014-1015, Role: Co-I.

10. Bill and Melinda Gates Foundation. Reducing Disease in Livestock Follow-On. 2011-2015, Role: Co-PI.

11. Merial Limited. Generating Porcine Stem Cells from Lung Tissue. 2013-2014, Role: Co-PI.

12. GALVmed. Vaccine Production in Chicken Induced Pluripotent Stem Cells. 2013-2014, Role: Co-PI.

13. Virginia Commonwealth University Center for Clinical and Translational Research. Generation of clinical grade patient specific differentiated cells from fibroblast derived human induced pluripotent stem cells for mitochondrial diseases. 2013-2014, Role: Co-I.

14. Morris Animal Foundation. Canine Urine Cells to Neural Progenitor Cells: A Novel Approach in Stem Cell Biology. 2013-2014, Role: Co-PI/Mentor.

15. Bill and Melinda Gates Foundation. Reducing Disease in Livestock Supplement. 2012-2013, Role: Co-PI.

16. China Scholarship Council. Differentiation of Human Pluripotent Stem Cells into Germ Cells. 2010-2012, Role: Co-PI.

17. Bill and Melinda Gates Foundation. Reducing Disease in Livestock. 2010-2011, Role: Co-PI.

ABSTRACTS

1. SE Sneed, KM Scheulin, EE Kaiser, MM Fagan, BJ Jurgielewicz, ES Waters, SE Spellicy, KJ Duberstein, EW Baker, SL Stice, HA Kinder and FD West. Magnetic Resonance Imaging and Gait Analysis Indicate Similar Outcomes between Yucatan and Landrace Porcine Ischemic Stroke Models. 2019 Georgia Bio Innovation Summit. 2019 October. Atlanta, GA.

2. S. E. Spellicy, E. E. Kaiser, M. Bowler, B. J. Jurgielewicz, R. L. Webb, F. D. West, S. L. Stice. Midline shift predicts functional outcomes in a porcine ischemic stroke model. Determining translational magnetic resonance imaging parameters predictive of


therapeutic efficacy in a porcine ischemic stroke model. 34th Annual MD/PhD National Student Conference. 2019 July. Copper Mountain, CO.

3. Kelly A. Scheulin, Franklin D. West and Shilpa Iyer. mRNA Reprogramming of Patient-Specific Mitochondrial Disease Fibroblasts into Human Induced Pluripotent Stem Cells. Mitochondrial Medicine 2019. 2019 June. Washington DC.

4. Jeon, J., J. Lourenco, E. Kaiser, E. Waters, K. Scheulin, M. Fegan, X. Fang, H. Kinder, S. Platt, K. J. Duberstein, T. R. Callaway, F. D. West, and H. J. Park. Changes of gut microbiome during acute stage of ischemic stroke in a pig model. Nutrition 2019 Conference. 2019 June. Baltimore, MD.

5. S. E. Spellicy, E. E. Kaiser, M. Bowler, B. J. Jurgielewicz, R. L. Webb, F. D. West, S. L. Stice. Determining translational magnetic resonance imaging parameters predictive of therapeutic efficacy in a porcine ischemic stroke model. Regenerative Medicine Workshop. 2019 March. Charleston, SC.

6. Kelly A. Scheulin, Franklin D. West and Shilpa Iyer. mRNA Reprogramming of Leigh’s Syndrome Patient Fibroblasts into Induced Pluripotent Stem Cells. Regenerative Medicine Workshop. 2019 March. Charleston, SC.

7. Holly A. Kinder, Emily W. Baker, Elizabeth W. Howerth, Kylee Jo J. Duberstein, Franklin D. West. Traumatic brain injury leads to cognitive and histological changes in a controlled cortical impact piglet model. Regenerative Medicine Workshop. 2019 March. Charleston, SC.

8. Holly A. Kinder, Emily W. Baker, Elizabeth W. Howerth, Kylee Jo J. Duberstein, Franklin D. West. Traumatic brain injury leads to cognitive and histological changes in a controlled cortical impact piglet model. GA Clinical and Translational Science Conference. 2019 February. Callaway Gardens, GA.

9. Gina A. Kim, Jennifer Mumaw, Kelly M. Scheulin, Elizabeth S. Waters, Lisa H. Williamson, Tamas Nagy, Franklin D. West, Stephen B. Harvey. Lameness in a Yucatan Minipig. American Association for Laboratory Animal Science (AALAS). 2018 November. Baltimore, MD.

10. Gina A. Kim, Jennifer Mumaw, Kelly M. Scheulin, Elizabeth S. Waters, Elizabeth W. Howerth, Franklin D. West, Stephen B. Harvey. Complications in a Stroke Model in Yucatan Minipigs. American Association for Laboratory Animal Science (AALAS). 2018 November. Baltimore, MD

11. Kelly Scheulin, Franklin West and Shilpa Iyer. mRNA Reprogramming of Leigh’s Syndrome Patient Fibroblasts into Induced Pluripotent Stem Cells. Cold Spring Harbor: The Evolving Concept of Mitochondria: From Symbiotic Origins to Therapeutic Opportunities. 2018: October. Cold Spring Harbor, NY.

12. Ajibola Bakare, Olivia Kolenc, Kelly Scheulin, Harrison E. Grace, Raj R. Rao, Edward J. Lesnefsky, Kyle P. Quinn, Franklin West and Shilpa Iyer. Creating patient-specific stem cell models and characterizing metabolic changes in Leigh’s Syndrome. 20th European Bioenergetics Conference. 2018: August. Budapest, Hungary.

13. Lohitash Karumbaiah, Franklin D. West and Steven L. Stice. A Translational Animal Model Platform for the Preclinical Assessment of Therapeutics for Severe TBI. Military Health System Research Symposium (MHSRS). 2018. August: Kissimmee, FL.

14. Brandon Campbell, Alice Shen, Simon Platt, Franklin West* and Qun Zhao*. Functional Connectivity Analysis in the Pig Stroke Model Using Deep Learning and


Dynamic Time Warping with Spectral Clustering. International Society for Magnetic Resonance in Medicine (ISMRM). 2018. June: Paris, France. *Co-corresponding authors

15. Robin L. Webb, Erin E. Kaiser, Brian J. Jurgielewicz, Samantha Spellicy, Shelley L. Scoville, Tyler A. Thompson, Raymond L. Swetenburg, David C. Hess, Franklin D. West, and Steven L. Stice. Human Neural Stem Cell Extracellular Vesicles Improve Recovery in a Porcine Model of Ischemic Stroke. International Society for Extracellular Vesicles. 2018. May: Barcelona, Spain.

16. Spellicy S, Kaiser E, Webb R, Jurgielewicz B, Scoville S, West F, Stice S. The role of neural stem cell derived extracellular vesicles as a therapeutic in a porcine middle cerebral artery occlusion model of stroke. American Physician Scientist Association 2018 Annual Meeting. 2018 April. Chicago, IL.

17. Spellicy S, Kaiser E, Bowler M, Jurgielewicz B, Webb R, West F, Stice S. Determining translation magnetic resonance imaging parameters predictive of therapeutic efficacy in a porcine ischemic stroke model. 2018 Society for Neuroscience. 2018 March. San Diego, CA.

18. Spellicy S, Jurgielewicz B, Kaiser E, Bowler M, Webb R, West F, Stice S. Multiparametric analysis of structural and functional correlations in a porcine MCAO model of stroke reveals divergent trends between treatment groups over time. Regenerative Medicine Workshop. 2018 March. Charleston, SC.

19. Madelaine N. Wendzik, Erin E. Kaiser, Anil Kumar, Xueyuan Yang, Elizabeth S. Waters, Monika Saini, Kelly M. Scheulin, Holly A. Kinder, Simon R. Platt, Jin Xie and Franklin D. West. Characterization of Acute Neuroinflammation in a Porcine Ischemic Stroke Model and Assessment of its Mitigation with Tanshinon-IIa-Loaded Nanoparticles. 2018 Regenerative Medicine Workshop at Charleston. 2018. March: Charleston, SC.

20. Erin E. Kaiser, Brian J. Jurgielewicz, Samantha E. Spellicy, Robin L. Webb, Simon R. Platt, Steve L. Stice, and Franklin D. West. Neural Stem Cell Derived Exosome Treatment Promotes Recovery in a Porcine Model of Ischemic Stroke. 2018 Regenerative Medicine Workshop at Charleston. 2018. March: Charleston, SC. *Poster Won Second Place in Competition

21. Erin E. Kaiser, Brian J. Jurgielewicz, Samantha E. Spellicy, Robin L. Webb, Simon R. Platt, Steve L. Stice, and Franklin D. West. Neural Stem Cell Derived Exosome Treatment Promotes Recovery in a Porcine Model of Ischemic Stroke. Georgia Clinical & Translational Science Conference. 2018. February: Braselton, GA. *Poster Won First Place in Competition

22. Emily W. Baker, Robin L. Webb, Erin E. Kaiser, Samantha Spellicy, Brian J. Jurgielewicz, Shelley L. Scoville, Tyler A. Thompson, Sumbul Fatima, Chirayukumar Pandya, Karishma Sriram, Raymond L. Swetenburg, Ali S. Arbab, Babak Baban, Krishnan M. Dhandapani, David C. Hess, M.N. Hoda, Franklin D. West, and Steven L. Stice. Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in Murine and Porcine Stroke Models. International Stroke Conference. 2018. January: Los Angeles.

23. Samantha E. Spellicy, Brian J. Jurgielewicz, Erin E. Kaiser, Robin L. Webb, Michael Bowler, Simon R. Platt, Franklin D. West, Steven L. Stice. Neural Stem Cell Derived Extracellular Vesicle Therapy in a porcine model of stroke. Neuroscience 2017. November: Washington D. C.


24. Madelaine N. Wendzik, Emily W. Baker, Holly A. Kinder, Silun Wang, Hui Mao, and Franklin D. West. Characterization of a Piglet Model of Traumatic Brain Injury Utilizing Non-Invasive Magnetic Resonance Imaging and Histological Assessment. Neuroscience 2017. November: Washington D. C.

25. Erin E. Kaiser, Brian J. Jurgielewicz, Samantha E. Spellicy, Robin L. Webb, Simon R. Platt, Steve L. Stice, and Franklin D. West. Neural Stem Cell Derived Exosome Treatment Promotes Recovery in a Porcine Model of Ischemic Stroke. Swine in Biomedical Research Conference. 2017. September: Baltimore, Maryland.

26. Kelly M. Scheulin, Emily W. Baker, Holly A. Kinder, Silun Wang, Candace C. Fleischer, Madelaine N. Wendzik, Elizabeth W. Howerth, Kylee Jo J. Duberstein, Hui Mao, Simon R. Platt, and Franklin D. West. Longitudinal Magnetic Resonance Imaging and Histological Assessment of a Porcine Traumatic Brain Injury Model. Southern Translational Education and Research Conference. September 2017, Augusta, GA.

27. Monika Saini, Emily W. Baker, Holly A. Kinder, Jessica M. Hutcheson, Kylee Jo J. Duberstein, Simon R. Platt, Elizabeth W. Howerth and Franklin D. West. Development and Characterization of a Scaled Controlled Cortical Impact Piglet Traumatic Brain Injury Model. Southern Translational Education and Research Conference. September 2017, Augusta, GA.

28. Erin E. Kaiser, Brian J. Jurgielewicz, Samantha E. Spellicy, Robin L. Webb, Simon R. Platt, Steve L. Stice, and Franklin D. West. Neural Stem Cell Derived Exosome Treatment Promotes Recovery in a Porcine Model of Ischemic Stroke. Southern Translational Education and Research Conference. 2017 September: Augusta, GA.

29. Samantha E. Spellicy, Brian J. Jurgielewicz, Erin E. Kaiser, Robin L. Webb, Michael Bowler, Holly A. Kinder, Simon R. Platt, Franklin D. West, Steven L. Stice. Neural Stem Cell-Derived Extracellular Vesicles as a Potential Therapeutic in an MCAO Porcine Model of Stroke. Southern Translational Education and Research Conference. 2017 September: Augusta, GA.

30. Elizabeth S. Waters, Kimberly D. Haight, Madelaine N. Wendzik, Monika Saini, Franklin D. West. Acute Induced Neural Stem Cell Transplantation Improves Blood Brain Barrier Stability in a Porcine Traumatic Brain Injury Model. Southern Translational Education and Research Conference. 2017 September: Augusta, GA.

31. Madelaine N. Wendzik, Emily W. Baker, Holly A. Kinder, Silun Wang, Hui Mao, and Franklin D. West. Assessment of a Piglet Model of Traumatic Brain Injury Utilizing Non-Invasive Magnetic Resonance Imaging. Southern Translational Education and Research Conference. 2017 September: Augusta, GA.

32. Kimberly D. Haight, Madelaine N. Wendzik, Elizabeth S. Waters, Kelly Scheulin, Monika Saini and Franklin D. West. Effect of Acute iNSC Transplantation on BBB Leakage in a Novel Porcine Controlled Cortical Impact TBI Model. Merial-NIH National Veterinary Scholars Symposium. 2017 July. Bethesda, Maryland.

33. Madelaine N. Wendzik, Emily W. Baker, Holly A. Kinder, Silun Wang, Hui Mao, and Franklin D. West. Characterization of a Piglet Model of Traumatic Brain Injury Utilizing Non-Invasive Magnetic Resonance Imaging and Histological Assessment. Society for Developmental Biology’s Southeastern Regional Meeting. 2017 May: Athens, GA.

34. Lily G. Francis, Erin E. Kaiser, Madelaine N. Wendzik, Simon R. Platt, Silun Wang,


David C. Hess, Hui Mao, and Franklin D. West. A Novel Porcine Model of Vascular Cognitive Impairment Demonstrates Changes in Cerebral Blood Flow and White Matter Tracts. Regenerative Bioscience Center Fellows Symposium. 2017 April: Athens, GA.

35. Kelly M. Scheulin, Anil Kumar, Madelaine N. Wendzik, Holly A. Kinder, Xueyuan Yang, Emily W. Baker, Erin E. Kaiser, Jen Xie and Franklin D. West. Nanoparticles Transport of FDA-Approved Drugs Across the Blood Brain Barrier in a Porcine Stroke Model Regenerative Bioscience Center Fellows Symposium. 2017 April: Athens, GA.

36. Madelaine N. Wendzik, Emily W. Baker, Holly A. Kinder, Silun Wang, Hui Mao, and Franklin D. West. Neural Injury Assessment Utilizing Non-Invasive Magnetic Resonance Imaging in a Porcine Model. Regenerative Bioscience Center Annual Symposium. 2017 April: Athens, GA.

37. Brian J. Jurgielewicz, Erin E. Kaiser, Samantha E. Spellicy, Robin L. Webb, Kylee Jo Duberstein, Simon R. Platt, Franklin D. West, Steven L. Stice. NPEX™ treatment improves spatiotemporal gait parameters in a middle cerebral artery occlusion porcine stroke model. Regenerative Bioscience Center Fellows Symposium. 2017 April: Athens, GA.

38. Kelly M. Scheulin, Anil Kumar, Madelaine N. Wendzik, Holly A. Kinder, Xueyuan Yang, Erin E. Kaiser*, Emily W. Baker, Elizabeth S. Waters, Jen Xie and Franklin D. West. Nanoparticles Transport of FDA-Approved Drugs Across the Blood Brain Barrier in a Porcine Stroke Model. Regenerative Bioscience Center Fellows Symposium. 2017 April: Athens, GA.

39. Samantha E. Spellicy, Brian J. Jurgielewicz, Erin E. Kaiser, Robin L. Webb, Michael Bowler, Holly A. Kinder, Simon R. Platt, Franklin D. West, Steven L. Stice. Behavioral Improvements Following Neural Stem Cell Derived Exosome Therapy in a Porcine Model of Stroke. Regenerative Bioscience Center Fellows Symposium. 2017 April: Athens, GA.

40. Brian J. Jurgielewicz, Erin E. Kaiser, Samantha E. Spellicy, Robin L. Webb, Simon R. Platt, Franklin D. West, Steven L. Stice. Neural Stem Cell Derived Exosome (NPEX™) Treatment in a Porcine Stroke Model. Integrated Research and Ideas Symposium. 2017 March: Athens, GA.

41. Brian J. Jurgielewicz, Erin E. Kaiser, Samantha E. Spellicy, Robin L. Webb, Kylee Jo Duberstein, Simon R. Platt, Franklin D. West, Steven L. Stice. Quantitative gait analysis in a porcine stroke model assessing the effects of a stem cell therapy. Regenerative Medicine Workshop. 2017 March: Hilton Head, SC.

42. Emily W. Baker, Simon R. Platt, Vivian W. Lau, Harrison E. Grace, Shannon P. Holmes, Liya Wang, Kylee Jo Duberstein, Elizabeth W. Howerth, Holly A. Kinder, Steve L. Stice, David C. Hess, Hui Mao, and Franklin D. West. Transplanted Induced Neural Stem Cells Differentiate and Integrate into the Brain Parenchyma of Ischemic Stroke Pigs Leading to Improved Tissue Recovery. International Stroke Conference. 2017. February: Houston, TX.

43. Holly A. Kinder, Emily W. Baker, Simon R. Platt, Shannon P. Holmes, Liya Wang, Vivian W. Lau, Harrison E. Grace, Elizabeth W. Howerth, Kylee Jo Duberstein, Steve L. Stice, David C. Hess, Hui Mao, and Franklin D. West. Transplanted induced neural stem cells promote neuron survival, reduce microglia activity, and stimulate endogenous


neuroblast migration to the site of injury in a porcine MCAO stroke model. World Stem Cell Summit. 2016. December: West Palm Beach, FL.

44. Emily W. Baker, Holly A. Kinder, Simon R. Platt, Shannon P. Holmes, Liya Wang, Vivian W. Lau, Harrison E. Grace, Elizabeth W. Howerth, Kylee Jo Duberstein, Steve L. Stice, David C. Hess, Hui Mao, and Franklin D. West. Transplanted induced neural stem cells differentiate and integrate in post-ischemic stroke brain tissue and promote recovery and regeneration in a porcine model. World Stem Cell Summit. 2016. December: West Palm Beach, FL.

45. Madelaine N. Wendzik, Emily W. Baker, Holly A. Kinder, Silun Wang, Hui Mao and Franklin D. West. Characterization of a Piglet Model of Traumatic Brain Injury Utilizing Non-Invasive Magnetic Resonance Imaging and Histological Assessment. World Stem Cell Summit. 2016. December: West Palm Beach, FL.

46. Franklin D. West, Simon R. Platt, Shannon P. Holmes, Liya Wang, Vivian W. Lau, Emily W. Baker, Harrison E. Grace, Elizabeth W. Howerth, Kylee Jo Duberstein, Steve L. Stice, David C. Hess and Hui Mao. Induced Neural Stem Cell Treated Stroke Pigs Show Improved White Matter Integrity and Brain Metabolism Post-Ischemic Stroke. International Stroke Conference. 2016. February: Los Angeles, CA.

47. Erin E. Kaiser, Kylee Jo Duberstein, Simon R. Platt, Vivian W. Lau, Emily W. Baker, Harrison E. Grace, Elizabeth W. Howerth, Shannon P. Holmes, Liya Wang, Steve L. Stice, Hui Mao and Franklin D. West. Quantitative Gait Analysis Demonstrates Significant Changes in Motor Function Post-Ischemic Stroke and Simulated Intraparenchymal Therapeutic Delivery in a Porcine Model. International Stroke Conference. 2016. February: Los Angeles, CA.

48. Venkat M. Ramakrishnan, Jeong Yeh Yang, Kevin T. Tien, John G. Maijub, Patrick O. Burchell, Braden R. Bocard, Stuart K. Williams, Marvin E. Morris, James B. Hoying, Richard Wade-Martins, Franklin D. West, and Nolan L. Boyd. Generation of an Engineered, Vascularized, iPSC-Derived Hepatic Module. 4th TERMIS World Congress. 2015. September: Boston, MA.

49. F. D. WEST, Y. LU, A. GALLEGOS-CARDENAS, P. YU, Y. LIU, J. Y. YANG AND S. L. STICE. Developmental Plasticity of Porcine and Avian Induced Pluripotent Stem Cells. Transgenic Animal Research Conference X. 2015. August: Tahoe City, CA.

50. Franklin D. West, Liya Wang, Hui Mao, Shannon P. Holmes, Simon R. Platt, Harrison Grace, Vivian Lau, Elizabeth W. Howerth, Trinh Nguyen, Lisa R. Reno, Amalia Gallegos-Cardenas, Jeong Yeh Yang, Kylee Jo Duberstein and Steve L. Stice. Longitudinal MRI and MRS Assessment of iPSC Neural Stem Cell Treatment in White Brain Matter. Regenerative Engineering and Medicine Conference. 2015. August: Atlanta, GA.

51. Holly A. Kinder, Emily L. Wyatt and Franklin D. West. Assessment of Learning Memory and Behavior in a Piglet Model. Regenerative Engineering and Medicine Conference. 2015. August: Atlanta, GA.

52. Emily L. Wyatt, Holly A. Kinder, Jessica M. Hutcheson, Elizabeth W. Howerth, W. Matthew Henderson, Kylee J. Duberstein and Franklin D. West. Development and Characterization of a Piglet Cortical Impact Traumatic Brain Injury Model. Regenerative Engineering and Medicine Conference. 2015. August: Atlanta, GA.

53. Shilpa Iyer, Harrison Grace, Franklin West, Edward Lesnefsky and Raj R. Rao. Reprogramming of Leigh’s fibroblast into induced pluripotent stem cells. Mitochondrial


Medicine 2015. 2015. June: Washington, DC. 54. Shannon P. Holmes, Liya Wang, Simon Ronald Platt, Hui Mao and Franklin D. West.

Development of a Porcine Middle Cerebral Artery Occlusion Stroke Model and Stroke Characterization with Quantitative MRI Techniques. International Society for Magnetic Resonance In Medicine. 2015. June: Toronto, Ontario, Canada.

55. Harrison Grace, W. Matthew Henderson, Vivian Lau, Trinh Nguyen, Simon R. Platt, Shannon P. Holmes, Elizabeth W. Howerth, Lisa R. Reno, Kylee Jo Duberstein, Steve L. Stice and Franklin D. West. Gray and White Matter Brain Metabolomic Profiling in a Porcine Model of Stroke with Human Induced Neural Stem Cell Treatment. American Physician Scientist Association. 2015. April: Chicago, IL.

56. Franklin D. West, Liya Wang, Shannon P. Holmes, Simon R. Platt, Harrison Grace, Vivian Lau, Elizabeth W. Howerth, Trinh Nguyen, Amalia Gallegos-Cardenas, Jeong Yeh Yang, Kylee Jo Duberstein, Steve L. Stice and Hui Mao. Regenerative Neural Stem Cell Therapy in a Pig Stroke Model. Regenerative Medicine and Cellular Therapy Research Symposium. 2015. April: Augusta, GA.

57. Holly A. Kinder, Emily L. Wyatt and Franklin D. West. Assessment of Learning Memory and Behavior in a Piglet Model. Regenerative Medicine and Cellular Therapy Research Symposium. 2015. April: Augusta, GA.

58. Emily L. Wyatt, Holly A. Kinder, Jessica M. Hutcheson, Elizabeth W. Howerth, W. Matthew Henderson, Kylee J. Duberstein and Franklin D. West. Development and Characterization of a Piglet Cortical Impact Traumatic Brain Injury Model. Regenerative Medicine and Cellular Therapy Research Symposium. 2015. April: Augusta, GA.

59. Harrison E. Grace, Franklin West, Edward Lesnefsky, Raj R. Rao, and Shilpa Iyer. Mitochondrial gene replacement in human pluripotent stem cells and neural progenitors for understanding genetics of mitochondrial diseases during early development. Stem Cell Energetics Symposia. 2014. December: Berkeley, CA.

60. Yangqing Lu, Franklin D. West and Steven L. Stice. Induced Pluripotency in Avian Embryonic Fibroblast. Asian Reproductive Biotechnology Sociaty Conference. 2014. November: Bangkok, Thailand.

61. Franklin D. West, Liya Wang, Hui Mao, Shannon P. Holmes, Simon R. Platt, Harrison Grace, Vivian Lau, Elizabeth W. Howerth, Trinh Nguyen, Lisa R. Reno, Amalia Gallegos-Cardenas, Jeong Yeh Yang, Kylee Jo Duberstein and Steve L. Stice. Longitudinal MRI and MRS Assessment of iPSC Neural Stem Cell Treatment in White Brain Matter. Regenerative Engineering and Medicine Conference. 2014. August: Athens, GA.

62. Harrison Grace, W. Matthew Henderson, Vivian Lau, Trinh Nguyen, Simon R. Platt, Shannon P. Holmes, Elizabeth W. Howerth, Lisa R. Reno, Kylee Jo Duberstein, Steve L. Stice and Franklin D. West. Metabolomic Profiling of Gray and White Matter Following Stroke and hiPSC Derived Neural Stem Cell Treatment. Regenerative Engineering and Medicine Conference. 2014. August: Athens, GA.

63. Emily L. Wyatt, Sean Marrache, Franklin D. West, and Shanta Dhar. A Lipophilic Therapeutic Nanoparticle Crosses the Blood-Brain Barrier and Targets Mitochondria in a Piglet Model of Traumatic Brain Injury. Regenerative Engineering and Medicine Conference. 2014. August: Athens, GA.

64. Holly A. Kinder, Emily L. Wyatt, Vivian W. Lau, Angel M. Padilla, and Franklin D. West. Near-Infrared Tracking of Human Induced Pluripotent Stem Cell Derived Neural


Stem Cells in the Pig Brain. Regenerative Engineering and Medicine Conference. 2014. August: Athens, GA.

65. Shanta Dhar, Sean Marrache, Emily L. Wyatt and Franklin D. West. A Blood-brain Barrier Penetrating Mitochondria Targeted Nanomedicine Platform for Combined Neuroprotectant-stem Cell Therapy for Traumatic Brain Injury. Regenerative Engineering and Medicine Conference. 2014. August: Athens, GA.

66. Yangqing Lu, Franklin D. West, Brian J. Jordan, Erin T. Jordan, Rachel West, Ping Yu, Ying He, Miguel A. Barrios, Ziying Zhu, James N. Petitte, Robert B. Beckstead, Steven L. Stice. Derivation of PGC-like cells From Chicken Embryonic Fibroblast by Cellular Reprogramming. Avian Model Systems Meeting. 2014 March: Cold Spring Harbor, NY.

67. Vivian Lau, Simon R. Platt, Shannon P. Holmes, Kylee Jo Duberstein, Elizabeth Howerth, Marc Kent, Lisa R. Reno, Steven L. Stice, David C. Hess, William D. Hill and Franklin D. West. Magnetic Resonance Imaging assessment of a pre-clinical middle cerebral artery occlusion ischemic stroke pig model. Southeastern Conference MRI/fMRI collaborative Mini-Conference. 2014 Feb: Athens, GA.

68. Leonardo Susta, Ying He, Jessica McCabe, Yangqing Lu, Franklin D. West, Steven L. Stice, Ping Yu, Claudio L. Afonso. Derivation of partially-resistant cIPSCs to Newcastle disease virus through multiple rounds of infection. Southern Conference on Avian Diseases. 2014 Jan: Atlanta, GA.

69. Brian J. Jordan, Yangqing Lu, Rachel C. West, Franklin D. West, Steven L. Stice and Mark W. Jackwood. Evaluation of chicken induced pluripotent stem cells as an in-vitro system for avian infectious bronchitis virus. Southern Conference on Avian Diseases. 2014 Jan: Atlanta, GA.

70. Franklin D. West, Simon R. Platt, Shannon P. Holmes, Kylee Jo Duberstein, Elizabeth Howerth, Holly A. Kinder, Emily L. Wyatt, Amie L. Goedeke, Lisa R. Reno, Steven L. Stice, David C. Hess and William D. Hill. Pre-Clinical Middle Cerebral Artery Occlusion Ischemic Stroke Pig Model. Termis-AM. 2013 Nov: Atlanta, GA.

71. Amalia Gallegos-Cardenas, Kai Wang, Erin T. Jordan, Rachel West, Franklin D. West Jeong-Yeh Yang and Steven L. Stice. Robust Generation of Neural Stem Cells from Pig Induced Pluripotent Stem Cells for Translational Neural Regenerative Medicine. Termis-AM. 2013 Nov: Atlanta, GA.

72. S.P. Holmes, S.R. Platt, K.J. Duberstein, E. Howerth, H.A. Kinder, E.L. Wyatt, A.L. Goedeke, L.R. Reno, S.L. Stice, D.C. Hess, W. D. Hill, F.D. West. ADC QUANTIFICATION IN A MIDDLE CEREBRAL ARTERY OCCLUSION ISCHEMIC PIG MODEL: CORRELATION TO CORTICAL ATROPHY. 2013 American College of Veterinary Radiology Annual Scientific Meeting. 2013 Oct: Savannah, GA.

73. A.C. Mannino, S. R. Platt, M. Kent, E. Howerth, S. P. Holmes and F. D. West. MRI T2 FLAIR Assessment of Cerebral Ischemic Infarction in a Porcine Stroke Model. 6th Annual Science of Veterinary Medicine Symposium. 2013 Oct: Athens, GA.

74. Vivian Lau, Simon R. Platt, Shannon P. Holmes, Kylee Jo Duberstein, Elizabeth Howerth, Marc Kent, Lisa R. Reno, Steven L. Stice, David C. Hess, William D. Hill and Franklin D. West. Magnetic Resonance Imaging and Functional Analysis of a Novel Middle Cerebral Artery Ischemic Stroke Model. 6th Annual Science of Veterinary Medicine Symposium. 2013 Oct: Athens, GA.

75. Vivian Lau, Simon R. Platt, Shannon P. Holmes, Kylee Jo Duberstein, Elizabeth Howerth, Lisa R. Reno, Steven L. Stice, David C. Hess, William D. Hill and Franklin D.


West. Magnetic Resonance Imaging and Functional Analysis of a Novel Middle Cerebral Artery Ischemic Stroke Model. 4th Annual Southern Translational Education and Research (STaR) Conference- Brain Injury: Pathways to Recovery. 2013 Sept: Augusta, GA.

76. Franklin D. West, Simon R. Platt, Kylee Jo Duberstein, Shannon P. Holmes, Elizabeth Howerth, Steven L. Stice, William D. Hill and David C. Hess. Development of a Novel Porcine Stroke Model for Stem Cell and Other Therapies. Regenerative Engineering and Medicine Conference. 2013 Sept: Atlanta, GA.

77. Sean Marrache, Emily Wyatt, Franklin D. West and Shanta Dhar. A Highly Lipophilic Nanoparticle Platform for the Treatment of Traumatic Brain Injury. Regenerative Engineering and Medicine Conference. 2013 Sept: Atlanta, GA.

78. Franklin D. West, Jeong-Yeh Yang, Kylee Jo Duberstein, Shannon P. Holmes, Jamie M. Chilton, Steven L. Stice, William D. Hill, David C. Hess and Simon R. Platt. Induced Pluripotent Stem Cell Derived Neural Progenitor Therapy for Treatment in a MCAO Ischemic Brain Injury Pig Model. International Stroke Conference 2013. 2013 Feb: Honolulu, HI.

79. Andy Zhu, Jun Ma, Harrison Grace, Steven L. Stice, Franklin D. West, Md. N. Hoda, Galina Kondrikova, Sudharsan Periyasamy-Thandavan, Maribeth Johnson, Mathew Hess, James E. Carroll, David C. Hess, William D. Hill. Localization of Stereotaxic Injections of Human iNP cells, One Week Post-MCAL Stroke, is Critical in Reducing Stroke Lesion Injury. International Stroke Conference 2013. 2013 Feb: Honolulu, HI.

80. Franklin D. West, Yubing Liu, Ping Yu, Yangqing Lu, Brian J. Jordan, Jeong-Yeh Yang, Robert B. Beckstead and Steven L. Stice. Expansion and Plasticity of Domestic Livestock Species Induced Pluripotent Stem Cells. ISSCR-Roddenberry International Symposium on Cellular Reprogramming. 2012 Oct: San Francisco, CA.

81. Amalia Gallegos-Cardenas, Rachel West, Jeong-Yeh Yang, Franklin D West and Steven L Stice. Advancing Translational Neural Regenerative Medicine by Using Pig Induced Pluripotent Stem Cells. Georgia Life Sciences Summit; 2012 Oct: Atlanta, GA.

82. Yangqing Lu, Franklin D. West, Claudio L. Afonso, Leonardo Susta, Ping Yu, Erin T. Jordan, Steven L. Stice. Animal induced pluripotent stem cells: a new cell source for vaccine production. 2nd Infectious Diseases World Summit; 2012 Jul: San Francisco, CA.

83. Franklin D. West, Elizabeth W. Uhl, Jeong Yeh Yang, Yangqing Lu and Steven L. Stice. Pig iPSCs are capable of generating normal chimeric pigs and undergo neural differentiation in vitro. Swine In Biomedical Research 2011; 2011 Jul: Chicago, IL.

84. Steve Stice and Franklin West. Porcine induced pluripotent stem cells for modeling regenerative medicine. Swine In Biomedical Research 2011; 2011 Jul: Chicago, IL.

85. S. Xiao, X. Cao, P. Yu, C.C. Chen, F. D. West, T. Wang, H. Lewin, S. Zhong. Comparison of the epigenomes of pig, mouse and human pluripotent cells. Swine In Biomedical Research 2011; 2011 Jul: Chicago, IL.

86. Henderson WM , West FD, Yang, JY, Stice SL, Smith MA. Metabolomic Analysis of Human Embryonic Stem Cell Derived Germ-like Cells Following Exposure to Endocrine Active Compounds. The Teratology Society; 2011Jun: San Diego, CA.

87. Stice SL, West FD, Smith MA, Henderson WM. Use of Human Progenitor Stem Cells for Toxicity Testing. The Teratology Society; 2011Jun: San Diego, CA.


88. Smith MA, West FD, Henderson WM, Stice SL. Characterization of the Endocrine Response of Human Embryonic Stem Cell Derived Germ-like Cells. The Teratology Society; 2011Jun: San Diego, CA.

89. Yangqing Lu, Franklin D. West, Brian Jordan, Jenny L. Mumaw, Erin T. Jordan, Robert Beckstead, Steve L. Stice. Derivation of Quail Induced Pluripotent Stem Cell. International Society of Stem Cell Research; 2011 Jun: Toronto, Ontario, Canada.

90. Franklin D. West, Elizabeth W. Uhl, Heather Stowe, Amalia Gallegos Cardenas, Yubing Liu, Ping Yu, Scott L. Pratt and Steven L. Stice. Chimeric Pigs Produced From Induced Pluripotent Stem Cells Demonstrate Normal Development and Lack Tumor Formation. International Society of Stem Cell Research; 2011 Jun: Toronto, Ontario, Canada.

91. Henderson, W. Mathew, West, Franklin D., Anderson, Benjamin M., Smith, Mary Alice, Stice, Steven L. Metabolomic Profiling of Human Embryonic Stem Cell Derived Germ-like Cells Following Exposure to Steroid Hormones. The Teratology Society; 2010 Jun: Louisville, (KY).

92. Franklin West, M.S. Natrajan, M.I. Roche-Rios and S.L. Stice. Bone Morphogenetic Protein and KIT Ligand Signaling Enhances Human Embryonic Stem Cell Differentiation into Early Male Germ Cells. Society for the Study of Reproduction; 2009 Sept: Pittsburgh, (PA).

93. A. Young, C. D. Sturkie, F. D. West, D. W. Machacek and S. L. Stice. Differentiation of Human Embryonic Stem Cell Derived Neural Progenitors Towards a Dopaminergic Phenotype. Neuroscience; 2008 November: Washington D. C.

94. F.D. West, M.S. Natrajan, M.I. Roche-Rios, M.A. Bedell and S.L. Stice. Bone Morphogenetic Protein and KIT Ligand Signaling Enhance Human Embryonic Stem Cell Differentiation into Early Sperm Cells. Georgia Life Sciences Summit; 2008 Sept: Atlanta, (GA).

95. Franklin West, Kurinji Pandiyan, Kelly Robbins and Steve Stice. Enrichment and Differentiation of Germ-Like Cells from Human Embryonic Stem Cells. Georgia Stem Cell Initiative; 2008 May: Athens, (GA). Recipient of 3rd place in poster competition.

96. Franklin West, Kurinji Pandiyan, Kelly Robbins and Steve Stice. Enrichment of Germ-Like Cells in Human Embryonic Stem Cells Cultures. GTECH Industry Partners Symposium; 2007 Oct: Atlanta, (GA).

97. F.D. West, K. Pandiyan, K. Robbins and S. L. Stice. Human Embryonic Stem Cells Differentiate into Sperm and Eggs Precursor Cells. Georgia Life Sciences Summit; 2007 Oct: Atlanta, (GA).

98. Franklin West, Kurinji Pandiyan, Kelly Robbins and Steve Stice. Enrichment of Germ-Like Cells in Human Embryonic Stem Cell Cultures. Society for the Study of Reproduction 40th Annual Meeting; 2007 Jul 21-25: San Antonio, (TX).

99. Simon, C.M., Schumm, M.A., Sturkie, C.D., West, F.D., Stice, S.L., and LaPlaca, M.C. A Tissue Engineering Approach for Transplanting Human Neuroepithelial Progenitors into the Contused Spinal Cord. Engineering Tissues; 2007 March; Hilton Head, (SC).

100. J. Mumaw, D. Machacek, M. Mitalipova, J. Shields, M. Galeano, M. Pecoraro, C. Sturkie, F. West, and S. L. Stice. Scanning Electron Microscopy on Human

Embryonic Stem Cells: Differentiation to Neural Progenitors to Neurons. The University of Georgia Biomedical and Health Science Institute 2006 Annual Retreat; 2006 Sept 22; Athens (GA).


101. West F., Pandiyan K., Robbins K. R., and Stice S. L. 2006. Differentiation of Primordial Germ Like Cells from Human Embryonic Stem Cells [Abstract]. The University of Georgia Biomedical and Health Science Institute 2006 Annual Retreat; 2007 t 22; Athens (GA). 102. Simon, C. M., Schumm, M. A., Sturkie, C. D., West, F.D., Stice, S. L., and LaPlaca, M. C. Tissue Engineered Constructs for Neuroepithelial Progenitor Transplanted to the Contused Rat Spinal Cord. 8th International Neurotrauma Symposium. 2006 May; Rotterdam, Netherlands. 103. CM Simon, MA Schumm, CD Sturkie, FD West, SL Stice, MC LaPaca. 2006. Transplantation of human neuroepithelial progenitor cells into the injured rat spinal cord: a tissue engineering approach. GTEC National Science Foundation site visit;

2006 17-19: Atlanta, (GA). 104. Michael A. Schumm, Crystal M. Simon, Carla D. Sturkie, Franklin D.West, Steve L. Stice, and Michelle C. LaPlaca. 2005. Human Embryonic Stem Cell Transplants to the Contused Spinal Cord. GTEC Educational Partners Symposium; 2005 Nov 8-10: Atlanta (GA). 105. Franklin D. West. The Effects of Male Population Density on Mate Choice and Offspring Production in Milkweed bugs, Onocopeltus fascoatus. Proceedings of the National Conference on Undergraduate Research. 1st ed. CD-ROM. 2002:

Asheville (NC).

TRAINEES Current Graduate Students

1. Elizabeth Waters, PhD- Estimated Graduation Date 05/23 2. Kelly Scheulin, PhD- Estimated Graduation Date 05/21 3. Erin Kaiser, PhD- Estimated Graduation Date 12/2019 4. Soo Kyung Shin, MS- Estimated Graduation Date 05/20 5. Sydney Sneed, MS- Estimated Graduation Date 12/20

Past Post-Doctoral Fellows

1. Monika Saini- 01/2017- 03/2018 Past Graduate Students

1. Emily Baker, PhD- Graduation Date 08/2017 2. Holly Kinder, PhD- Graduation Date 08/2017 3. Vivian Lau, MS- Graduation Date 08/2017 4. Trinh Nguyen, MS- Graduation Date 05/2016 5. Jessica Hutcheson, MS- Graduation Date 05/2015 6. Yubing Liu, PhD- Graduation Date 05/2016 7. Ping Yu, MS- Graduation Date 05/2014

PATENTS

1. Methods of Producing Germ-Like Cells and Related Therapies. Patent application number: 20110044954. Inventors: Franklin West (Athens, GA, US), Steven Stice (Athens, GA, US). Class name: Drug, bio-affecting and body treating compositions whole live micro-organism, cell, or virus containing animal or plant cell. Publication


date: 2011-02-24. SERVICE TO SCIENTIFIC COMMUNITY

Review Panels 1. NIH Development 1 (DEV1) Study Section, Standing Member 07/2018-current 2. Swine in Biomedical Research Conference 2020, Program Committee Member

08/2019-current 3. American Heart Association Fellowship, Brain Stroke Basic Science 2, Reviewer

10/2019 4. American Heart Association, International Stroke Conference, Scientific Session

2019, Reviewer 09/2019 5. DoD Combat Casualty Care Research Program (CCCRP); Medical Technology

Enterprise Consortium (MTEC); Multi Domain Live Saving Trauma Innovation (MuLTI) Award, Grant Reviewer 07/2019

6. National Science Centre, Poland, Panel NZ5, Ad Hoc Grant Reviewer 10/2018 7. American Heart Association, International Stroke Conference, Scientific Session

2019, Reviewer 09/2018 8. NIH Acute Neural Injury and Epilepsy (ANIE) Study Section, Ad Hoc Member

02/2018 9. Stem Cell Therapies as an Emerging Paradigm in Stroke Consortium Member 2017 10. NIH Development 1 (DEV1) Study Section, Ad Hoc Member 10/2017 11. American Heart Association, International Stroke Conference, Scientific Session

2016, Reviewer 06/2016 12. NIH Development 1 (DEV1) Study Section, Ad Hoc Member 06/2016 13. TERMIS-AM Conference, Expert Reviewer 07/2013 14. CRDF Global, Expert Reviewer 03/2013 15. NIH Study Section Cell, Computational and Molecular Biology Small Business

(STTR/SBIR), Ad Hoc Member 05/2012 Professional Journals Editorial Board 1. American Journal of Stem Cells: Associate Editorial Board Member 2012-Current 2. Journal of Stem Cell Research and Transplantation: Editorial Board Member 2014-

Current 3. Journal of Veterinary Science and Research: Editorial Board Member 2014- Current 4. World Journal of Biological Chemistry: Editorial Board Member 2013- 2017 Reviewer for the Following Journals Stem Cells and Development, PLOS ONE, Cellular Reprogramming, Molecular Reproduction and Development, Journal of Biotechnology, BioMed Research International, GENE, Journal of Equine Veterinary Science, Cells Tissues Organs, Encyclopedia of Molecular Cell Biology and Molecular Medicine, The Encyclopedia of Biotechnology in Agriculture and Food, Tissue Engineering, Journal of Visualized Experiments, Journal of Proteome Research Service Committees


University of Georgia 1. University of Georgia Research Foundation Board Member 2018- Current 2. Department of Animal and Dairy Science Graduate Curriculum Committee 2013-

Current 3. Department of Animal and Dairy Science Undergraduate Curriculum Committee

2011- Current External 1. Sims Academy of Innovation and Technology- Biotech Advisory Committee 2019-

Current RESEARCH WORKSHOP EXPERIENCE

2011 National Dairy Research Institute (NDRI) “Hands on training on stem cell for quality animal production.” Karnal, India.

§ International Stem Cell Expert and Instructor 2010 University of Georgia Induced Pluripotent Stem Cell Workshop. Athens,

GA. § Director and Instructor

2004- 2009 National Institutes of Health Human Embryonic Stem Cell Toolbox (HEST) Workshop. Athens, GA and Richmond, VA.

§ Instructor (2007-2009) § Support Staff (2004-2006)

TEACHING EXPERIENCE

Fall 2011-current ADSC 3130 Animal Biotechnology (taught every Fall Semester) This is an introductory course in cutting-edge

biotechnologies that can be used for animal and human health and research. This course uses primary literature to cover advanced topics in stem cell biology, biomaterials, large animal models of disease and development, and diagnostics. This class covers basic cellular and molecular biology techniques and their applications in a real-world research setting. The topics are broad in scope and cover cell biology, genetics and other similar themes. The typical enrollment for this course is 30 students.

Spring 2014-current ADSC 8120 Experimental Methods in Animal Biotechnology (taught every Spring Semester)

This is a hands-on training course in basic cell culture, RNA and protein laboratory skills including RT-PCR, immunocytochemistry, and flow cytometry. Course discussions include basic technique application stratagies, limitations of approaches, and data interpretation. We also examine the literature utilize these approaches to better understand the real-world applications of these techniques. The typical enrollment for this course is 10 students.


Spring 2012-current ADSC/BIOL/BCMB/CBIO/GENE 4960/4970/4980/4990 Undergraduate Research (taught every Semester); The typical enrollment for these courses in total is 10 students. Fall 2013-Spring 2015 ADSC 8888 Current Literature in Stem Cell Biology and

Regenerative Medicine (taught every Semester) This is a seminar and journal club style course covering

current research activities in regenerative medicine laboratories on campus. This course offers trainees an opportunity to present their research in a symposium like setting, yet still get constructive critiques of their ongoing research and presentation skills. Trainees also have the opportunity to present primary literature in the areas of stem cells, tissue engineering, toxicology, neural and bone injury, wound healing and many other topics under the purview of regenerative medicine. The typical enrollment for this course is 25 students.

Spring 2012-Spring 2013 ADSC 6110 Experimental Methods in Animal Biotechnology (taught every Spring Semester); Currently ADSC 8120 Spring 2012, Fall 2012, ADSC 8700 Special Problems in Animal and Dairy Science I; Spring 2017-Fall 2018 (taught intermittently); The typical enrollment for this course was 2 students. Spring 2012, ADSC 3700 Special Problems in Animal Dairy Sciences Spring 2017, (taught intermittently); The typical enrollment for this Spring 2019 course was 2 students. Summer 2012 Young Scholars Program 2006-2008 Center for Undergraduate Research Opportunities (CURO) Research Mentor

§ Mentor of Ms. Muktha Natrajan § Mentor of Ms. Kurinji Pandiyan

2007 Animal Biotechnology Course Teaching Assistant 2006-2007 Introduction to Animal and Dairy Science Laboratory Teaching Assistant

2006 Young Scholars Program § Mentor of Mr. Amadu Ndiaye

2006 Companion Animal Care Course Teaching Assistant 2005 Cloning and Stem Cells Course Teaching Assistant 2005 Horse Operant Conditioning and Training Course Teaching Assistant PROFESSIONAL AFFILIATIONS AND HONORS

2012-Present Society for Neuroscience, Member 2011-Present American Heart Association, Member 2011-Present Who’s Who in Agriculture Higher Education, Member 2006-Present International Society of Stem Cell Research, Member 2006-Present Gamma Sigma Delta: The Honor Society of Agriculture, Member 2002-Present Golden Key International Honour Society, Member 2001-Present National Society of Collegiate Scholars, Member


2019 University of Georgia College of Agricultural and Environmental Science Young Alumni Award Recipient 2013 Travel Award for the 4th Annual Southern Translational Education and Research (STaR) Conference- Brain Injury: Pathways to Recovery 2012 Named “Emerging Scholar 2012” by Diverse Magazine 2010 Named “Georgia Trends Top 40 Under 40: Georgia’s Best and Brightest” by Georgia Trend Magazine 2007-2009 Society for the Study of Reproduction, Member 2004-2008 Animal and Dairy Science Graduate Student Association

§ President 2005-2006 2008 Georgia Tech Student Travel Award (Meeting: Regenerative Medicine: Advancing to Next Generation Therapies) 2006 Out Standing Teaching Assistant Award for the College of Agricultural and Environmental Sciences, Recipient 2005 University of Georgia Graduate Student Travel Grant (Meeting: Therapeutic Potential of Stem Cells in Reproductive Medicine)

SELECTED INVITED PRESENTATIONS

2019 “Neuroprotective and Regenerative Stem Cell and Extracellular Vesicle Therapies in a Pig Ischemic Stroke Model.” Frontiers in Stem Cells and Regeneration-Marine Biological Laboratory. October: Woods Hole, MA.

2019 “Stem Cell Therapy in Treating Stroke and Traumatic Brain Injury in Pig Models.” University of Louisville Cardiovascular Medicine Grand Rounds. April: Louisville, KY.

2019 “Neuroprotective and Regenerative Stem Cell and Extracellular Vesicle Therapies in a Pig Ischemic Stroke Model.” Cardiovascular Innovation Institute Research Symposium-University of Louisville. Keynote Speaker. April: Louisville, KY.

2018 “Neuroprotective and Regenerative Stem Cell and Extracellular Vesicle Therapies in a Pig Ischemic Stroke Model.” St Mary’s Neurology Conference. October: Athens, GA.

2018 “Neuroprotective and Regenerative Stem Cell and Extracellular Vesicle Therapies in a Pig Ischemic Stroke Model.” Frontiers in Stem Cells and Regeneration-Marine Biological Laboratory. October: Woods Hole, MA.

2017 “Neuroprotective and Regenerative Stem Cell Therapy in a Pig Stroke Model.” University of Arkansas. March. Fayetteville, AK.

2016 “Saving the Sumatran Tiger and Clouded Leopard: Developing the Technology to Create Sperm from Endangered Species Skin Cells.” Nebraska Coalition for Lifesaving Cures. November: Omaha, NB.

2015 “Developmental Plasticity of Porcine and Avian Induced Pluripotent Stem Cells.” Transgenic Animal Research Conference X. August: Tahoe City, CA.


2015 “Production of Genetically Modified Organisms Utilizing Stem Cell Technology.” Southern Association of Agricultural Scientists. February. Atlanta, GA.

2014 “Pig Induced Pluripotent Stem Cells as a Tool for Transgenic Animal Development and a Model for Stem Cell Therapy for Stroke.” Guangxi University. December. Nanning, Guangxi, China.

2014 “Assessing iNeural Stem Cell Therapy as a Treatment for Stroke in a MCAO Pig Model." University of Illinois, Neuroscience Program. October. Urbana-Champaign, IL.

2012 “Disease Resistant Chickens.” Bill and Melinda Gates Foundation. July. Atlanta, GA.

2012 “Porcine Regenerative Stem Cell Therapy Ischemic Injury Model.” Foods and Nutrition Department, University of Georgia. February. Athens, GA.

2011 "Newcastle Resistance in Poultry: A Stem Cell Approach." Poultry Science Department, University of Georgia. October. Athens, GA.

2011 “Stem Cell Derived Germ Cells: Improving the way we live, eat and the world around us.” AHS CARET, College of Agricultural and Environmental Sciences, University of Georgia. August. Savannah, GA. 2011 “Porcine Induced Pluripotent Stem Cells: A tool to study stem cell therapy

efficacy and safety.” India Veterinary Research Institute. March. Bareilly, Uttam Pradesh, India.

2011 “Stem Cells: A model for germ cell development and a tool for neural cell therapy.” National Dairy Research Institute. March. Karnal, Haryana, India.

2011 “Derivation of Induced Pluripotent Stem Cells from Domestic Livestock Species.” Animal and Veterinary Science, Clemson University. February. Clemson, SC.

2011 “Stem Cell Derived Germ Cells: A model for human germ cell development.” Morehouse College. February. Atlanta, GA. 2011 “Stem Cell Derived Germ Cells: Improving the way we live, eat and the world around us.” ARCS Foundation. January. Atlanta, GA. 2010 “Opportunities and Challenges of Generating Stem Cell Derived Germ Cells.” National Science Foundation Integrated Graduate Education and Research Training Grant (IGERT) program. Georgia Institute of Technology. November. Atlanta, GA. 2008 “Enrichment and Differentiation of Human Embryonic Stem Cells into Male Germ-Like Cells.” National Institute of Health Human Embryonic Stem Cell Toolbox (HEST) Workshop. Richmond, VA. 2008 “Stem Cells and Cloning: Great Potential and Challenges.” University of Georgia STARS (Student and Teacher Applying Real-Life Science) Program. Athens, GA 2007 “The Science of Stem Cells and Cloning.” Athens Area Chamber of Commerce. Athens, GA.


2007 “Cloning and the Social and Economic Implications.” Kiwanis Club. Commerce, GA. 2005 “Cloning: Science and Function.” Teachers Training Teachers. Athens, GA

Technical Skills

• Human, Primate and Mouse Adult, Embryonic, and Induced Pluripotent Stem Cell and General Cell Culture • Immunocytochemistry • Flow Cytometry and Florescence Activated Cell Sorting (FACS) • Quantitative and Qualitative Reverse Transcription Polymerase Chain Reaction (RT-PCR) • Western Blotting • Mouse and Embryo Dissection • Transfection and Transduction • Disk Spinning Unit Microscopy • Open Water Diving, Certified

Documents

Franklin D. West Associate Professor Regenerative ......F. D. West Curriculum Vita 1 CURRICULUM VITAE Franklin D. West Associate Professor Regenerative Bioscience Center 425 River