Focus on UltramicrotomyWe at LKB want to focus your attention on the solution,not on the problem-get your problems In focus and solvethem the LKB-way.

LKB ULTROTOME III SOLVESPROBLEM OF "COMPRESSION"'Compression' (not to be confused with "chatter"), Is adeformation of the section caused during cutting wherebythe section length becomes shorter than the pyramidheight Compression deforms the specimen ultrastructure,makes direct measurement of micrographs Inaccurate(without corrections), and morphology mlslesdlng.

Design of LKB optical system (viewing at 45" Incidentangle), checks compression and estimates correction fac-tor where it has occured. Low speeds eliminate or mini-mize compression, the LKB ultramlcrotome can produceusable sections at 0.5 and 0 2 mm/sec, because there, areNO VIBRATIONS.

The llrst or an LKB-serlas dealing with problems In ultra-microtomy.

Answer to many more problems provided by uniquedesign features:

Cutting speeds: Widest range available, 20-0.1 mm/sec.

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The Journal ofGeneral Microbiology

Volume 48, Part 2, August 1967

B. D. W. Jarvis, V. J. Williams & E. F. AnnisonEnumeration of cellulolytic cocci in sheep rumen by usinga fluorescent antibody techniqueS.T.Williams A F. L. Davies Use of a scanningelectron microscope for the examination of actino-mycetesB. W. Nelson & R. J. Roantree Analyses of lipo-polysaccharides extracted from penicillin-resistant,serum-sensitive salmonella mutantsB. J. Hammond, Margot Kogut & J. W. LightbownAnalogue computer studies of the growth characteristicsof Escberichia coli following dihydrostreptomyctn treat-ment

D. Sompolinsky, Zippora Ernst-Geller & S. SegalMetabolic disorders in thiamineless dwarf strains ofStaphylococcus aureusS. Horvath Development of competence in cultures ofBacillus subtil is inoculated with different numbers ofbacteriaA. A. Lindberg Studies of a receptor for Felix 0-1phage in Salmonella minnesotaR. W. Tuveson, D. J. West & R. W. Barratt Glu-tamic acid dehydrogenases in quiescent and germinatingconidia of Neurospora crassaJ. O. Lampen Cell-bound penicillinase of BacillusUcheniformis; properties and purificationJ. O. Lampen Release of penicillinase by BacillusUcheniformisR. C. Hignett & D. S. Kirkham The role of extra-cellular melanoproteins of Venturis inaequalis in hostsusceptibilityK. Nordstrom Induction of the petite mutation inSaccharomyces cerevisiae by N-methyl-N'-nitro-N-nitro-soguanidineP. J.Dubash & D. V. Rege Chlorophyll formation inEuglena gracilis var. bacillaris: interference by analoguesof purines, pyrirrtidines and amino acidsD. L. Bruce, D, C. B. Duff & N. J. Antla The identifi-cation of two antibacterial products of the marineplanktonic alga Isochrysis galbanaW. T. Dobrzanski & H. Osowiecki Isolation and someproperties of the competence factor from Group Hstreptococcus strain CHALLISJanet Brotherton Lack of swelling and shrinking ofPityrosporum ovale in media of different osmotic pressuresand its relationship with survival in the relatively dryconditions of the scalpH. C. de Klerk & J. A. Smlt Properties of a Lacto-bacillus fermenti bacteriocin

45s. net ($7.50)

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Published for the Society forGeneral Microbiology

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The focusing and specimencontrols are centralised and per-mit comfortable operation witheither the left or right hand. Thefocusing controls are concentricon a vertical'axis and the coarsefocusing is by lever and scrollmechanism. The fine adjustmentis by fine screw and lever givinga smooth and sensitive response.Good rigidity is obtained by theexceptional width of the focusingslides and the large diameterball bearings.

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"History in the Breaking!"In 1950 the first glass knife for ultramlcro-tomy was made, by methods which wererather unconventional and did not exactlyguarantee reproduclblllty, by breaking abottle.

In 1964 glass was still being broken tomake knives for ultramlcrotomy but LKB hadproduced the KnlfeMaker. The KnlfeMakerrevolutionized the production of glass knivesfor ultramlcrotomy by making It possible toproduce knives easily, quickly, with a choiceof predictable edge angle, economically, andwith reproduclbllity.

Now In 1966, LKB has once again madehistory in breaking glass for knives, by In-troducing the unique Damping Device thatadds .even' greater sensitivity (and moreworking edge per knife), to an Instrumentthat has proved its reliability in ultramlcro-tomy laboratories and research establish-ments throughout the world.

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Journal of the MarineBiological AssociationVolume 47, Number 2, June 1967

Carl Frederick Abel Pantln 1899-1967:ObituaryE. D. S. Corner, C. B. Cowey & S. M.Marshall On the nutrition and metabolismof zooplankton. V. Feeding efficiency ofCalanus finmarchicusB. S. Newell The determination of am-monia in sea waterG. R. Fortter A new deep-sea ray from theBay of BiscayG. R. Fonter The growth of Haliotistubtrculata: results of tagging experimentsIn Guernsey 1963-65Ray Gibson Occurrence of the entocom-mensal rhynchocoelan, Malacobdella grossa,in the oval plddock, Zirfaea crispata. on theYorkshire coastH. E. Hinton Plastron respiration in themarine fly CanaceI. A. N. Luca* Two new marine species ofParaphysomonasT. H. Carefoot Studies in a sublittoralpopulation of Aplysia punctateJ. P. Rlley & T. R. S. Wilson The pigmentsof some marine phytoplankton speciesF. S. Russell On the occurrence of thescyphomedusan Pelagia noctiluca in theEnglish Channel in 1966C. Edwards A calycopsid medusa from theFirth of ClydeD. A. Jones & E. Naylor The distributionof Eurydice [Crustacea: Isopoda] in Britishwaters, Including E. affinij new to BritainJ. Mauchllne The biology of Schistomysisspiritus [Crustacea, Mysidacea]N. A. Holme Changes in the bottom faunaof Weymouth Bay and Poole Bay followingthe severe winter of 1962-63G. A. W . Battin Nomograms for chloro-phyll determinationsJ. S. Alexandrowicz Receptor organs Inthe coxal region of Palinurus vulgaritN. C. Flemmlng & A. H. Stride Basalsand and gravel patches with separate Indi-cations of tidal current and storm-wavepaths, near PlymouthMary Parke & Irene Manton The specificIdentity of the algal symbiont in Convolutaroscoffensls

£5 net ($16.75)Annual Subscription £14 ($47.00)

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The Journal ofExperimental BiologyVolume 46, Number 3, June 1967

William H. Evoy, Donald Kennedy &Donald M. Wilson. Discharge patterns ofneurones supplying tonic abdominal flexormuscles In the crayfishJ. E. Treherne & S. H. P. Maddrell Mem-brane potential! in the central nervous systemof a phytophagous Insect (Carausius morosus)D. W . T. Crompton & P. F. V. Ward Lacticand succlnic acids as excretory products ofPolymorphic minutus (AcanthocephaJa) In vitroSteven Vogel Flight in Drosophila. III. Aero-dynamic characteristics of fly wings and wingmodelsM. C Brown Some effects of receptor musclecontraction on the responses of slowly adapt-ing abdominal stretch receptors of the crayfishColin Little Ionic regulation In the queenconch, Strombus gigas (Gastropoda, Proso-branch la)D. C. Sandeman Excitation and inhibition ofthe reflex eye withdrawal of the crab CarclnusEmile van Handel Non-dependence of thesaturation of depot fat on temperature andphotoperiod In a hibernating mosquitoR. L. C. Pilgrim Some responses to light in aspecimen of Pelagohydra tnlrabilis Dendy, 1902(Coelenterata: Hydrozoa)D. W. Sutcllffe Sodium regulation In thefresh-water amphipod, Gimmarus pulex (L.)D. W . Sutcllffe & J.Shaw The sodiumbalance mechanism In the fresh-water amphi-pod, Gammarus lacuttrit SirsD. W . Sutcllffe Sodium regulation In theamphipod Gammarus dutbenl from brackish-water and fresh-water localities in BritainW . E. Balfour & E. N. Wlllmer Iodine ac-cumulation in a nemertlne, Lintus ruberChrlstoph von Campenhausen The abilityof Umulus to see visual patternsM. B. V. Roberts Slow activity In the ner-vous system of the earthworm, LumbricusterrestrisDeForest Mellon, Jr & George, J. MpltsosResponse heterogeneity In adductor muscleefferents of the surf clam

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PHASE CONTRAST AND INTERFERENCE MICROSCOPY FORCELL BIOLOGISTSDr K. F. A. Ross 70s. netThis book provides a practical guide to the use of both Phase Contrast and Inter-ference Microscopy and attempts a proper explanation of the optical theory underly-ing the working of these instruments. Applications for the use of haematology arediscussed as well as aspects which apply to many other fields of cytology.

AN INTRODUCTION TO THE HAEMOGLOBINOPATHIES ANDTHE METHODS USED FOR THEIR RECOGNITIONH. E. Hutchison 30s. netThis volume presents in terms understandable to the medical graduate a brief accountof the structure of the normal and abnormal haemoglobins; to outline the ways inwhich variants may arise and to describe the effects they may produce and the patho-logical mechanisms involved.

THE LYMPHOCYTE IN IMMUNOLOGY AND HAEMOPOIESISJ. M. Yoffey £6 netThis book contains forty-three papers presented at an International symposium held atBristol in April 1966. They range from discussion and original work on the origin ofthe lymphocyte, to its role in immunology and transplantation.'Any of the papers could be cited as adding to the corpus of knowledge in this highlyspecialized field.' British Book News.

— — — — .EDWARD ARNOLD. _ — _ —41 Maddox Street, London, W. 1

THE PROTOZOAK. Vickerman, Ph.D., and F. E. G. Cox, Ph.D.The second book in the ' Introductory Studies in Biology' series initiatedby Stephen Hurry's strikingly successful The Microstructure of Cells.

Superb illustrations (photographs, micrographs and specially madeline drawings), and a page size large enough to do them justice, are out-standing features of this book which presents new accounts of the typesof protozoa most commonly encountered at sixth form and first yearUniversity level: amoeba, euglena, chlamydomonas, trypanosoma, mono-cystis, plasmodium and paramecium. There are sections on protozoa ascells and organisms, which take account of recent advances in cell biology,genetics and parasitology, and the final section deals with finding andkeeping specimens.

Publication: 18 September 1967 125. 6d. net

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INFORMATION FOR CONTRIBUTORS

i Manuscripts should be sent to The Editors,Journal of Cell Science, Department of Zoology,Cambridge, England.

2. Manuscripts must be typewritten, in doublespacing throughout (including tables, references andlegends). Each table should be typed on a separatesheet. Legends to figures should be typed in asingle series and placed at the end of the manuscript.Papers must be fully corrected by the author, and acharge will be made for excessive alteration in proof.

3 A short title of not more than 40 characters, foruse as page headings, should be supplied if the fulltitle is longer than this.

4 Manuscripts must contain a Summary of notmore than 500 words, placed immediately afterthe title page. Contributors should also send threecopies of an Abstract for distribution to abstractingjournals. The abstract must be not more than 100words long and should be headed by the author'sname and address and the title of the paper. Bothsummary and abstract must be intelligible withoutreference to the main text.

5 The list of References must be given inalphabetical order of authors' names. The titles ofjournals should be abbreviated in accordance withthe World List of Scientific Periodicals, 4th ed. (1963).The following style is used:

BAKNICOT, N. A. & HUXLEY, H. E. (1965).Electron microscope observations on mitoticchromosomes. Q. Jl microsc. Sci. 106, 197-214.

MAZIA, D. (1961). Mitosis and the physiology ofcell division. In The Cell, vol. 3 (ed. J. Brachet& A. E. Mirsky), pp. 77-412. New York andLondon: Academic Press.

Citations in the text are given in the following form:Jones & Smith (i960) or (Jones & Smith, i960).Where there are more than two authors the firstcitation should include all the names and subsequent

citations should be in the form (Jones et al. i960).Where more than one paper by the same authors)have been published in the same year they are citedas Jones (1960a), Jones (19606) etc.

6 Text figures should preferably be drawn abouttwice final size; very large drawings should beavoided. Photographic reproductions of drawingscannot always be satisfactorily reproduced. Themaximum printed size of a drawing is 5 in. by8 in. Lettering will be inserted by the printers andshould be indicated on drawings in faint bluepencil or on a tracing-paper overlay. It should be inlower case, and abbreviations should not be used ifthere is space for complete words.

7 Photographs should preferably be submitted thesame size as they are to appear. The maximum areafor a plate is si in. by 8J in. Where several photo-graphs make up a plate they should be accuratelymounted on one sheet of cardboard. Irregularlyshaped photographs or plates should be avoidedwherever possible. Lettering on plates will be in-serted by the printers and should be indicated eitheron a duplicate, marked set of prints or on a tracing-paper overlay bearing accurately marked outlinesof the objects indicated. Authors may be asked tocontribute to the cost of plates in excess of four.

8 Text figures and photographs should benumbered in a single series, all text figures pre-ceding the photographs. Each individual drawingor photograph should be numbered separately(Fig. 1, Fig. 2 and so on).

9 Where appropriate the magnifications ofillustrations should be indicated by scales drawn onthem. Magnifications may also be stated in thelegends.

10 Authors will receive 50 offprints free of chargeand may order additional copies when proofs arereturned.