January 1993 Volume 26 No. 1

FLUORIDE JOURNAL

of the

international

Society for

Fluoride

Research

THE INTERNATIONAL SOCIETY FOR FLUORIDE RESEARCH

President Prof H Tsunoda lwate Medical University Morioka, Japan

Second Vice President Dr Miklos Bely National Institute of

Rheumatolog y Budapest, Hungary

Prof A K Susheela All India Institute

of Medical Science New Delhi, India

Prof A W Burgstahler University of Kansas Lawrence, Kansas USA

Dr K R Bulusu National Env. Eng. Res. Inst. Nagpur, India

Prof K Yoshitaka Shi a University

Shiga-Ken, Japan

Prof J Franke Orthopdic Clinic Medical Academy Erfut, Germany

ofMedica1 Science

Dr G J Ballentyne Universrty of Victoria Victoria BC, Canada

Dr Y Kaneko School of Dentistry Showa Universrty Shinegawa-Ku Tokyo, Japan

Dr Edward Czerwinski Kracow Academy of Medicine Kracow, Poland

Dr K Kono Dept. Hygiene 8 Public Health Osaka Medical College Osaka, Japan

Dr M Chikuma Osaka University of

Osaka, Japan

Prof J e w Krechniak Dept. of Toxicology Medical Academy Gdansk, Poland

Pharmaceutical Sciences

Vice President Prof Ming-Ho Yu Huxley College of Environmental Studies Bellingham, Washington USA

Secretary Prof G W Miller Utah State Universsity Logan, Utah USA

ADVISORY BOARD

Prof Zan-Dao Wei Guiyang Medical College Guizhou, China

Dr C James Lovelace Humbolt State University Arcata, California USA

Prof G W Miller Utah State Universsrty Logan, Utah USA

Dr Guy Milhaud Service de Pharmacie et

Toxicologie, Ecole Nationale VMrinaire d'Alfort

Maison-Alfort, France

Dr John Colquhoun 216 Atkinson Road, Titirangi Auckland, New Zealand

EDITORIAL BOARD

Prof Barbel Dominok Seevveg 5, 7513 Cottbus Germany

Prof S Bang lnstitut de Morphologie Centre Medical Universitaire Geneva, Switzerland

Dr K A V R Krishnamachari Director, Regional Medical

Research Centre Bhubaneswar, India

Prof Shouren Cao Chinese Academy of

Beijing, China

Prof Lennart Krook NY State College of

Veterinary Medicine Cornell University Ithaca, New York USA

Prof G Neil Jenkins Newcastle upon Tyne England

Preventive Medicine

Treasurer Dr John Colquhoun 216 Atkinson Road, Titirangi Auckland, New Zealand

Editorial office Dr John Colquhoun (Editor) Mr J M Caris (Manager) 216 Atkinson Road, Titirangi Auckland, New Zealand

Dr Miklos B6ly National Institute of

Rheumatology Budapest, Hungary

Dr M e d Hans Runge Orthopadic Clinic Martin Luther University Halle, Germany

Prof Ming-Ho Yu Huxley College of

Bellingham, Washington US1

Prof H Tsunoda lwate Medical Universrty Morioka, Japan

Prof Y Yoshida Osaka Medical College Osaka, Japan

Environmental Studies

Dr John R Lee 9620 Bodega Hwy, Sebastopol, California USA

Dr James C Pushnik Dept. Biological Sciences California State University Chico, California USA

Dr Zygmunt Machoy Department of Biochemistry Pomeranian Medical Academ Sznecin, Poland

Prof S P S Teotia LLRM Medical College Meerut, India

Dr Sally W Wheeler Hawkesbury Agricultural

Research Unit Richmond NSW, Australia

Dr F Murray School of Environmental

and Life Sciences Murdoch Universrty Murdoch WA, Australia

Vol. 26 No.1 1993 Pages 1-78

FLUORIDE QUARTERLY REPORTS

ISSUED BY THE INTERNATIONAL SOCIETY FOR FLUORIDE RESEARCH

Co-Editors: Prof A W Burgstahler Lawrence, Kansas USA Editor: Dr John Colquhoun Auckland, New Zealand

Prof G W Miller Logan, Utah USA Dr K A V R Krishnamachari Bhubaneswar, India

CONTENTS

EDITORIALS THE KYOTO CONFERENCE

PUBLICATIONS I Gene W Miller .... .__ 1 - 2

John Colquhoun ........................................................................................................ 2

RESEARCH REPORTS

Gene W Miller, USA ....

THE EFFECT OF FLUORIDE ON HIGHER PLANTS: WITH SPECIAL EMPHASIS ON EARLY PHYSIOLOGICAL AND BIOCHEMICAL DISORDERS

CYTOGENETIC EFFEC G

EFFECT OF CARBON TREATMENT ON AQUEOUS FLUORIDE DETERMINATIONS

BONE STRUCTURE ASSESSMENT ON RADIOGRAPHS OF DISTAL RADIAL METAPHYSIS IN CHILDREN WITH DENTAL FLUOROSIS

BENEFICIAL EFFECTS OF ASCORBIC ACID AND CALCIUM ON REVERSAL OF FLUORIDE TOXICITY IN MALE RATS

CHANGES OF SEROTONIN CONTENT AND TURNOVER RATE IN HYPOTHALAMUS OF FEMALE RAT DURING FLUOROSIS

AN EXPERIMENTAL STUDY FOR EARLY DIAGNOSTIC FEATURES IN FLUOROSIS

N P Gritsan, Ukraine ........................................................................................ 23 - 32

Albert W Burgstahler and Jefiey Scott Lockhart, USA .................................... 33 - 36

D Chlebna-Sokol and E Czencinsk, Poland . ............................. 3 7 - 4 4

N J Chinoy, Manisha Sharma and Mathews Michael, India ............................... 45 - 56

ShuDe Yuan, QiWen Xie and FuYing Lu, China .......

Jei Wang, Ze-Ai Zheng, Lu-Shu Zhang el al, China .......................................... 61 - 65

ABSTRACTS TIME TRENDS FOR BONE AND JOINT CANCERS AND OSTEOSARCOMAS IN THE SEER PROGRAM, NATIONAL CANCER INSTITUTE

A BRIEF REPORT ON THE ASSOCIATION OF DRINKING WATER FLUORIDATION AND THE INCIDENCE OF OSTEOSARCOMA AMONG YOUNG MALES

IS THERE A LINK BETWEEN FLUORIDATED WATER AND OSTEOSARCOMA?

R N Hoover, S Devesa, K Cantor and J F Fraumeni Jr ............................................ 66

Perry D Cohn ......... ................................ ........ ........ 67

S M McGuire, E D Vanable, M H McGuire el al USA ............................................ 68

ABSTRACTS (continued) BONE CANCER INCIDENCE RATES IN NEW YORK STATE: TIME TRENDS AND FLUORIDATED DRINKING WATER

M C Mahoney, P C Nasca, W S Burnett and J M Melius, USA INTERNATIONAL TRENDS IN THE INCIDENCE OF BONE CAN ARE NOT RELATED TO DRINKING WATER FLUORIDATION

EVALUATION OF THE NATIONAL TOXICOLOGY PROGRAM (NTP) CANCER BIOASSAY ON SODIUM FLUORIDE

FLUORIDES AND OSTEOPOROSIS

THE EFFECT OF FLUORIDE ON OSTEOGENESIS IN VlTRO

SIDE EFFECTS OF FLUORIDE THERAPY Michel Laroche and Bernard Mazieres, France

THE EFFECT OF PROLONGED INGESTION 0 (1OOPPM) OF FLUORINE ON OSSEUS TISSUES OF RATS

THE EFFECT OF FLUORIDE TREATMENT ON BONE MINERAL CRYSTALS IN THE RAT

SODIUM FLUORIDE PREVENTS BONE LOSS IN PRIMARY BlLlARY CIRRHOSIS

DO ESTROGENS IMPROVE BONE MINERAL DENSITY IN OSTEOPOROTIC WOMEN OVER AGE 65

.......... 68

S C Freni and D W Gaylor, USA .............. ......... 68

Edward J Calabres, USA .................................................................................. 69 - 70

Michael Kleerekoper and Raphaella Balena, U

H C Tenebaum, J Richards, D Holmyard ef al, Canada ...

M Tsuchida, I Okayasu, K Teraoka ef ul, Japan ........... ...... 72

M D Grynpas and C Rey, Canada ................................................

N Guanabens, A Pares, L Delrio er al, Spain ........................................................... 73

C W G E Dailey, C Cheney el al, USA ......................................................... 74 EFFECTS OF EXPERIMENTAL FLUORIDE POISONING ON AL-P ACTIVITY AND cAMP LEVEL IN PLASMA AND BONE IN RATS: STUDIES WITH PAIR FEEDING C

SURVEY OF BO-D DRINKING DA 1. LEAD, CADMIUM, ARSENIC, ALUMINUM AND FLUORIDE

EFFECT OF HARD CHEESE EXPOSURE, WITH AND WITHOUT FLUORIDE PRERINSE, ON THE REHARDENING OF SOFTENED HUMAN ENAMEL

DOES THE NAKED FLUORIDE ION EXIST?

T Iwasaki, T Sat0 and M Niwa, J .......................... .... 74

R W Dabeka, H B S Conacher, J Salminen ef a,, Canada

I Gedalia, I Davidov, I Lewinstein and L Shapka, Israel .......................................... 75

................. 75 - 76

Taposh K Das and A K Susheela, India ................................................................... 76

.......... Konrad Seppelt, Germany CHRONIC FLUORIDE TOXICITY AND PITUITARY-ADRENAL FUNCTION

EFFECTS OF FLUORIDE, LITHIUM, AND STRONTIUM ON GROWTH AND ACID PRODUCTION OF MUTANS STREPTOCOCCI AND ACTINOMYCES VISCOSUS

A D Eisenberg M D Oldershaw, M E J Curzon and S L Handelman, USA .............. 76

J L Shupe, R H Bruner, J L Seymour and C L Alden, USA ................ THE PATHOLOGY OF CHRONIC BOVINE FLUOROSIS - A REVIEW

lMnTR0 IMMUNE MODULATION OF POLYMORPHONUCLEAR LEUKOCVE ADHESIVENESS BY SODIUM FLUORIDE

SERUM FLUORIDE AS AN INDICATOR OF OCCUPATIONAL HYDROFLUORIC ACID W O S U R E

K Kono, Y Yoshida, M Watanabe ef ul, Japan ............................. EFFECT OF DIETARY FLUORIDE ON SELENITE TOXICITY IN THE

JL. Gomezubric, J Liebana, J Gutierrez and A Castillo, Spain ............. ....... 77

Q Yu, F L Cerklewski, P D Whanger ef al, USA ...............................