First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip

by Robert Farra, Norman F. Sheppard, Laura McCabe, Robert M. Neer, James M. Anderson, John T. Santini, Michael J. Cima, and Robert Langer

Sci Transl MedVolume 4(122):122ra21-122ra21

February 22, 2012

Published by AAAS

Fig. 1 The microchip-based drug delivery device and overview of study design.

Robert Farra et al., Sci Transl Med 2012;4:122ra21

Published by AAAS

Fig. 2 PK dosing results.

Robert Farra et al., Sci Transl Med 2012;4:122ra21

Published by AAAS

Fig. 3 Bone marker and calcium measurements.

Robert Farra et al., Sci Transl Med 2012;4:122ra21

Published by AAAS

Fig. 4 Tissue histology results from a representative patient, MC-0012.

Robert Farra et al., Sci Transl Med 2012;4:122ra21

Published by AAAS