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Figure 1
Black bars = Small IntestineWhite Bars = Colon
Figure 2
Table 1
Group Supplemented
Bran (%)
Total (n) Male Female
Group A 0 7 4 3
Group B 5 4 4 0
Group C 15 16 9 7
Group D 30 8 4 4
Total 35 21 14
Figure 3
PCA OPLS-DA
A B
Figure 4
A B
Table 2
No. Retention Time (min) m/z ±0.02 Regulation
1 2.52 148.99 Up-regulated2 7.71 189.02 Up-regulated3 2.54 212.95 Up-regulated4 3.19 218.01 Up-regulated5 2.54 218.97 Up-regulated6 0.92 160.07 Down-regulated7 4.48 226.97 Down-regulated
Table 3Protein Fold Change Direction
Serine protease inhibitor A3G 4.35 ↑
Haptoglobin 3.35 ↑
Major urinary protein 2 3 ↑
Fibrinogen gamma chain 2.83 ↑
Fibrinogen beta chain 2.77 ↑
Alpha 1 acid glycoprotein 1 2.44 ↑
Ig mu chain C region secreted form 2.39 ↑
Ig kappa chain C region 2.27 ↑
Alpha 2 macroglobulin 2.05 ↑
Apolipoprotein A 1 1.95 ↑
Serine protease inhibitor A3 K 1.92 ↑
Serum albumin 1.82 ↑
Immunoglobulin J chain 1.77 ↑
Gelsolin 1.77 ↑
Ig gamma 1 chain C region secreted form 1.7 ↑
Serum amyloid P component 1.65 ↑
Alpha 1 antitrypsin 1 4 1.6 ↑
Adiponectin 1.58 ↑
Interleukin 1 receptor accessory protein 1.57 ↑
Complement factor H 1.52 ↑
Alpha 1 antitrypsin 1 1 1.52 ↑
Kininogen 1 1.49 ↑
Complement factor 1 1.49 ↑
Fetuin B 1.4 ↑
Angiotensinogen 1.38 ↑Hemopexin 1.34 ↑
Alpha 1 antitrypsin 1 2 1.3 ↑
Beta 2 glycoprotein 1 1.28 ↑
Apolipoprotein 1 IV 1.28 ↑
Liver carboxylesterase N 1.27 ↑
Murinoglobulin 1 1.27 ↑
Afamin 1.25 ↑
Alpha 1 antitrypsin 1 5 1.2 ↑
Alpha 2 HS glycoprotein 1.14 ↑
Complement C3 1.08 ↑
Serotransferrin 1.06 ↑
Hemoglobin subunit epsilon Y2 0.25 ↓
Carboxylesterase 3 0.22 ↓
