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Facile Preparation of Allyl Amines and Pyrazoles by Hydrazinolysis of 2-Ketoaziridines

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Page 1: Facile Preparation of Allyl Amines and Pyrazoles by Hydrazinolysis of 2-Ketoaziridines

2006

Ring opening reactionsO 0132 Facile Preparation of Allyl Amines and Pyrazoles by Hydrazinolysis of 2-Keto-

aziridines. — Hydrazinolysis of 2-ketoaziridines, including N-protected as well as bicyclic ones, results in formation of allylamines and/or pyrazoles. The hydrazinolysis of homochiral substrates proceeds without racemization. — (CHEN, G.; SASAKI, M.; YUDIN*, A. K.; Tetrahedron Lett. 47 (2006) 3, 255-259; Dep. Chem., Univ. Toronto, Toronto, Ont. M5S 3H6, Can.; Eng.) — Mais

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