Upload
others
View
3
Download
0
Embed Size (px)
Citation preview
caLIBRAte Risk models testing
Project #686239, Funded by the Horizon 2020 Framework Programme of the European Union
caLIBRAteUser testing sessions on next generation decision-making tools
for risk governance of nanomaterials
THE STOFFENMANAGER NANO AND LICARA NANOSCANMarch 15th, 2018 -13.00 CET
Organizers and presenters:
Andrea Porcari and Elisabetta Borsella, Italian Association for Industrial Research (Airi),
Guillaume Flament, Claire Skentelbery and Maite del Corte,
Nanotech Industry Association (NIA),
Remy Franken, Thies Oosterwijk, TNO – Innovation for Life
Keld Alstrup Jensen, National Research Center for the Working Environment (NRCWE)
The webinar will start at 13.00
caLIBRAte Risk models testing
Agenda
• Welcome (13.00)
• Andrea Porcari, Introduction to caLIBRAte
• Remy Franken, Stoffenmanager Nano: introduction and case study
• Question & Answers
Webinar break (14.15-14.30)
• Thies Oosterwijk, LICARA nanoSCAN: introduction and case study
• Question & Answers
• Concluding remarks (15.30)
Moderator: Guillaume Flament
caLIBRAte Risk models testing
Get insights on state-of-the-art activities on risk governance of NM
Have practical info and tailored suggestions on how to use the models in your daily working activities
Give your views and needs on how to further improve the models, and design the caLIBRAte System of Systems
Why the webinars on risk models testing
caLIBRAte Risk models testing
Who are we
▪ Coordinator: NRCWE (KA Jensen)
▪ 24 (+1) Partners
– 21 from Europe (2 Switzerland)
– 2 from USA
– 1 from South Africa
– 1 from Canada
▪ Budget ca. 10 Mio € – ca. 8 Mio € from the EC
▪ Duration: May 2015 to Oct 2019
Green Decisions
DIALOGIK
University of
Helsinki
Health
Canada
caLIBRAte Risk models testing
The challenges
▪ Use of manufactured nanomaterials continue to grow
▪ The risk analysis is still technically and methodologically limited, and lacking robust sources of quantitative data
▪ Uncertainties in the safety of nanomaterials are seen by stakeholders as a major limitation to market
▪ Rising demand for improved (risk and innovation) governance approaches, to:
– Inform and support researchers toward safe design of nano-related products
– Facilitate decision-making on risk uncertainties (comparative, qualitative, precautionary …)
– Support compliance with regulatory frameworks
– Provide homogenous rules for safe management of NM
caLIBRAte Risk models testing
The goals of caLIBRAte
Establish a versatile, nano-risk governance framework
for assessment and management of human and environmental risks of
manufactured nanomaterials (MN) and MN enabled products
➢ Approach (highlights):
• Harvesting and implementing results from state-of-the-art research on risk
governance (risk assessment, management and communication)
• Develop, improve, integrate nano-specific models and methods into a system-of
systems (SoS)
• Support decisions along the R&I value chain, from basic research to market launch.
➢ Target: research organizations, companies, insurers authorities and other stakeholders
involved in research, prioritization and management of occupational, consumer and
environmental risks of NM
➢ Ambition: quality and trust in the caLIBRAte framework models will exceed the current
level of most existing REACH tools.
caLIBRAte Risk models testing
Decision-making along the R&I value chain
Idea
screen
Gate 1
Scoping
Screen
Gate 2
Go to
development
Gate 3
Go to test
Gate 4
Go to Launch
Gate 5
Post-Launch
review
Gate 6
Dis
co
ve
ry
an
d id
ea
s
Sc
op
ing
Sta
ge
1
Bu
ild
bu
sin
es
s c
as
e
Res
ea
rch
an
d
de
ve
lop
me
nt
Te
sti
ng
an
d V
ali
da
tio
n
La
un
ch
Ho
rizo
n
Sc
an
nin
g/
Mo
nit
ori
ng
Cooper Stage-Gate® Idea to launch model
Safety?
Add Risk assessment & management to the Stage-Gate decision process
material, product and safety knowledge
caLIBRAte Risk models testing
Where are we in caLIBRAte?
Existing modelsUser-friendliness
Sensitivity
calibrationperformance
New ModelsUser-
friendliness
Sensitivity
calibration
SoS Framework demonstration
caLIBRAte Risk models testing
The testing of the (existing) risk models
Models and applicationdomains
Workers(labs)
Workers(All)
Users &Consumers
Environment
Waste/end-of-life
All Life Cycle
Stoffenmanager Nano ✓
LICARA nanoscan ✓ ✓ ✓ ✓
Swiss Precautionary Matrix ✓ ✓ ✓ ✓
GUIDEnano ✓ ✓ ✓ ✓
Nanosafer CB ✓
Control banding nanotool ✓ ✓
SimpleBox4Nano (SB4N) ✓ ✓ ✓
SUNDs ✓ ✓ ✓ ✓
caLIBRAte Risk models testing
Agenda
• Welcome (13.00)
• Andrea Porcari, Introduction to caLIBRAte
• Remy Franken, Stoffenmanager Nano: introduction and case study
• Question & Answers
Webinar break (14.15-14.30)
• Thies Oosterwijk, LICARA nanoSCAN: introduction and case study
• Question & Answers
• Concluding remarks (15.30)
Moderator: Guillaume Flament
Stoffenmanager Nano 1.0
Remy Franken & Thies Oosterwijk
Stoffenmanager Nano 1.0
Exposure measurements are complex and therefore expensive and time-consuming
• Control banding / Risk banding: first Tier for qualitative risk assessment => Work in progress…
Assists producers, formulators and end users to prioritize health risks of working with MNO
• Hazard x Exposure = Risk Applicability domain:
• Only inhalation exposure• All types of MNO and all processes with MNO• Workers only
Education (PIMEX, good practices), community portal Result: Freely available IT-tool for prioritizing nano-specific risks
August 10, 2011
Wouter Fransman
Stoffenmanager Nano 1.0
Stoffenmanager Nano 1.0: Hazard banding
Stoffenmanager
Non-Nano
Nano
Hazard band
E
C
D
B
A
Soluble
Insoluble
Persistent
Fibers
Other MNO
Indication for
C (-M); R; T+
Indication for
M (+C); S
Harmful /
irritant
Low-
hazardous
profile
T / causes
burns / resp.
irritation
Unknown
Classification
based on data
MNO or their
parent
materials
Stoffenmanager Nano 1.0: Hazard banding
E
C
D
Hazardous
properties
unknown
E
D
Parent material
classified for CMRS?
no
yes
MNO included in
the list of most
widely used
MNO’s?
no
Expert judgment,
based on data
available and primary
particle size
yes
< 50 nm?
Stoffenmanager Nano 1.0: Exposure banding
Source domains (Schneider et al., 2011)
1. Point or fugitive emission during the production phase prior to harvesting the bulk material
2. Handling and transfer of bulk powdered MNO
3. Dispersion of (solid or liquid) intermediates or ready-to-use MNO-containing products
4. Activities resulting in fracturing and abrasion of MNO-containing end products
Stoffenmanager Nano 1.0: Exposure banding
Source Receptor
Emission
- Product
- Activity
Transmission
- Local control
- Ventilation
Immission
- Personal enclosure
- PPE
Input parameterse.g.: activity, dustiness powder, concentration
liquid, local controls
ModelBased on source-receptor approach (Schneider et al.
2011)
Multiplier Exposure band4 categories
Stoffenmanager Nano 1.0: Risk banding
Hazard band
Exposure band
A B C D E
1 3 3 3 2 1
2 3 3 2 2 1
3 3 2 2 1 1
4 2 1 1 1 1
Future plans: Stoffenmanager Nano 2.0
Exposure banding• Include semi-quantitative exposure values for benchmarking• Include different values for different size classes
Hazard banding• Hazard assessment based on phys/chem properties
Towards a quantitative risk assessment
Input from Calibrate project
Case study: Production of MWCNT
Production of MWCNT for the use of fuel cell batteries
Synthesis process through chemical vapor condensation, assumed pure product
Setting is a pilot plant Duration of the process is ~2 to 4 hours once a week 1 operator present
caLIBRAte Risk models testing
Agenda
• Welcome (13.00)
• Andrea Porcari, Introduction to caLIBRAte
• Remy Franken, Stoffenmanager Nano: introduction and case study
• Question & Answers
Webinar break (14.15-14.30)
• Thies Oosterwijk, LICARA nanoSCAN: introduction and case study
• Question & Answers
• Concluding remarks (15.30)
Moderator: Guillaume Flament
LICARA NANOSCANA tool for the self-assessment of benefits and risks of nanoproducts
Thies Oosterwijk, Remy Franken
LICARA PROJECT
Life Cycle Approach and human Risk Assessment, product stewardship
and stakeholder risk/benefit communication of nanomaterials
Aims to develop an approach for SMEs to assess over the life cycle
the human and environment risks
and the economic, environmental and social opportunities.
LICARA NanoScan
PRESENT SITUATION ON NANO TECHNOLOGY
DEVELOPMENT WITHIN SME’S
Nano products provide benefits and business opportunities
However, the possibility of human and environmental risks
may spoil the party
It is (too) difficult and costly to assess these risks
Risk Assessment and Life Cycle Assessment are complex
and costly to perform
data are scarce and if available highly uncertain.
it is difficult to “repair” data gaps
LICARA NanoScan
NEED TO SUPPORT SME’S ON DECISION MAKING IN
UNCERTAINTY ON NANO PRODUCT DEVELOPMENT
Including both benefits and risks
Translating present available scientific knowledge into understandable
information
Tapping on specific know-how of SMEs
To sketch the pros and cons of a nanoproduct in relation to a
conventional product and over the full life cycle
LICARA NanoScan
NEED TO SUPPORT SME’S ON DECISION MAKING IN
UNCERTAINTY ON NANO PRODUCT DEVELOPMENT
Qualitative / semi-quantitative giving the fact that little quantitative data
is available with high uncertainties
Using existing tools
Helps users to show possible benefits of their innovation using
nanomaterials
Based on tool output, users can anticipate potential risks of their
innovation
LICARA NanoScan
LICARA NANOSCAN IN CALIBRATE WP2
Tool objectively scored high for early stages of innovation (stage 2 and
3)
Tool fills data gaps with default worst-case choice
LICARA NanoScan
LICARA NanoScan
Conceptual framework on nano benefits and risks
3. Societal benefits
7. Decision support
1. Environmental benefits
4. Public health & environmental risks of nano
5. Occupational health risks of
nano
6. Consumer health risks
of nano
0. Nanoproduct and legislation
2. Economic benefits
NanoRiskCatStoffenmanager
Nano
Stoffenmanager
Nano
Precautionary
Matrix
Precautionary
Matrix
LICARA NanoScan
Risks
Public health & environmental
System knowledge
Potential effect
Potential input environment
Occupational health
Exposure potential
Hazard
Consumer health
Exposure potential
Exposed population
Hazard
Benefits
Environmental
Manufacturing
Use
End-of-life
Economic
Market potential
Profitability
Development stage
Societal
Technological breakthrough
Highly qualified labour
Global health or food
SERIES OF QUESTIONS TO FILL IN THE TOOL
LICARA NanoScan
WEIGHED RESULTS
LICARA NanoScan
Example: scratch and corrosion
resistant nano silica coating
APPLICATIONS OF LICARA NANOSCAN
LICARA NanoScan
Competition (opportunity, performance)• Compare products against new developments/product
substitution by competitors• Examine new technologies from competitors and
whether or not to invest in such technology
Market / client (benefit, risk)• Identify customers’
benefits of using nanoproducts
• Support customers in safe and responsible nanoproduct handling
Suppliers (resource analysis)• Check which
nanoproducts perform best and have the lowest occupational health risks
Reflection (internal risk analysis)• Verify whether risks are at the very least counter-
balanced by benefits
CASE STUDY: MWCNTS IN FUEL CELLS
The present case study investigates a PEM fuel cell in which MWCNT
replace carbon black (not nano-sized).
The function of the MWCNT is conducting electricity and act as carrier
for the catalyst.
https://diamonds.tno.nl/licara/
https://nano.stoffenmanager.nl/
LICARA NanoScan
CASE STUDY: MWCNTS IN FUEL CELLS
Expected benefit
Replacing carbon black with MWCNT leads to an increased surface
available for the catalyst and a significant decrease of the amount of
Platinum.
Together with an increased electric conductivity an increased overall
efficiency can be expected.
LICARA NanoScan
CASE STUDY: MWCNTS IN FUEL CELLS
Potential risks:
There is a potential release of MWCNT into the environment during
particle production.
No risks are expected during the use-phase of the fuel cell.
The CNT may end up in a municipal incineration and might be burned
as hazard waste at high temperature.
Platinum is recycled using dangerous chemicals
LICARA NanoScan
THANK YOU FOR YOUR
ATTENTION
Take a look:TIME.TNO.NL
caLIBRAte Risk models testing
Agenda
• Welcome (13.00)
• Andrea Porcari, Introduction to caLIBRAte
• Remy Franken, Stoffenmanager Nano: introduction and case study
• Question & Answers
Webinar break (14.15-14.30)
• Thies Oosterwijk, LICARA nanoSCAN: introduction and case study
• Question & Answers
• Concluding remarks (15.30)
Moderator: Guillaume Flament
caLIBRAte Risk models testing
IMPORTANT!
Test the tool and provide your feedback
Provide your comments in the online user feedback form
Quick feedback just after the webinar
More in depth feedback in case of access and use of the model
Compile the form multiple times, if needed to integrate your comments after use of the tool
https://it.research.net/r/calibrateusertesting
Note: only aggregated data will be made public - data management by Airi
Get access to the models and use it by yourself:
https://nano.stoffenmanager.nl/Default.aspx?lang=en
https://diamonds.tno.nl/licara/
caLIBRAte Risk models testing
Overall opinion on the pros and cons of the tool
Level of usability
Barriers, road-blocks, additional features
Level of accessibility of input and output data
Relevance/usefulness of the functions
Motivation
Feedback form - contents
http://www.nanocalibrate.eu/risk-governance-models
12 questions, tick boxes and open comments, overall max 10-15 minutes compilation time
caLIBRAte Risk models testing
Calendar of risk models testing
webinars
Scheduled:
• GUIDEnano: February 22
• Swiss Precautionary matrix: March 8
• Stoffenmanager nano and LICARA Nanoscan: March 15
• SimpleBox4Nano: March 22
To be planned:
• Nanosafer CB and Control banding nanotool (April)
• SUNDs (April)
http://www.nanocalibrate.eu/risk-governance-models
caLIBRAte Risk models testing
Thank you for your participation and active contributions
www.nanocalibrate.eu
caLIBRAte Risk models testing