Page 1 of 2

Higher National Diploma in Biomedical Science

Batch 2 & 3

Part 1 [LO: 3 & 4]

Re-sit

Qualification Higher National Diploma in Biomedical Science

Level 5

Module Name Human Physiology

Module Number 04

Module Tutors Dr. Deepthi De Silva MBChB, MRCP(UK)

Dr. Minerva A De Silva MBBS, M Phil (Peradeniya)

Dr. W A D Lakmali Amarasiri MBBS, PhD (Kelaniya)

Time Allowed 2 hours (9.00am to 11:00am)

Exam Date 26th February 2013

Summary of Learning Outcomes Part 1 consists of two questions of one hour each, which is clinically oriented and integrated. These two questions are related to learning outcomes (3) and (4). (3) Describe the components of homeostatic control systems.

(4) Discuss the coordination of organ systems in the maintenance of a constant internal

environment.

Page 2 of 2

Part 1 - (Answer BOTH questions)

Question 1 A 50 year old man complaining of a pain radiating down his left arm was diagnosed with a myocardial infarction (heart attack). His blood pressure was 90/50 mmHg and pulse rate was 35/min. a. Explain the reason for a heart attack causing ‘pain radiating down his left arm’. [30 marks]

b. State the normal blood pressure in an adult and comment on this patient’s blood pressure.

[15 marks]

c. Comment on this patient’s pulse rate. [10 marks] d. Outline the pathway for excitation of the heart (transmission of the cardiac impulse).

[15 marks]

e. State the relationship between, pulse rate, cardiac output and blood pressure. [20 marks] f. Explain the reason for this patient’s blood pressure. [10 marks]

[Total marks 100]

Question 2 The following is an arterial blood gas report of a 24 year old female who presented with difficulty in breathing. Her respiratory rate was found to be 38/min.

pH : 7.31 (7.36 – 7.4) PaO2 : 58 mmHg (97 – 100 mmHg) PaCO2 : 48 mmHg (40 – 46 mmHg) HCO3

- : 24 meq/L (22 – 26 meq/L)

a. Comment on her pH, PaCO2, PaO2 and HCO3

- levels. [5 x 4 marks=20 marks]

b. State the acid base imbalance in her. [10 marks]

c. State the 3 compensatory mechanisms likely to be activated in her. [15 marks]

d. List 3 buffers found in plasma and explain their importance. [15 marks]

e. List 3 buffers present in the kidney and explain their importance. [15 marks]

f. Explain the reason for her respiratory rate. [25 marks]

[Total marks 100]

~ End of Paper ~ © BMS Printed on: 2/23/2013 3:32:13 PM BIO HP P 1| Feb 13 [B 2,3] RS