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Exam 2
Wednesday, Mar 4 !!!
Lectures 7 - 11
Chapters 11, 12 & 13
50 multiple choice questions
Page723MolecularBiologyoftheCell(©GarlandScience2008)
Figure12‐35aMolecularBiologyoftheCell(©GarlandScience2008) Figure12‐36cMolecularBiologyoftheCell(©GarlandScience2008)
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Figure12‐38MolecularBiologyoftheCell(©GarlandScience2008) Figure12‐39bMolecularBiologyoftheCell(©GarlandScience2008)
Figure12‐39aMolecularBiologyoftheCell(©GarlandScience2008) Figure12‐40MolecularBiologyoftheCell(©GarlandScience2008)
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Figure12‐41aMolecularBiologyoftheCell(©GarlandScience2008) Figure12‐41bMolecularBiologyoftheCell(©GarlandScience2008)
Figure12‐42MolecularBiologyoftheCell(©GarlandScience2008) Figure12‐43MolecularBiologyoftheCell(©GarlandScience2008)
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Figure12‐44MolecularBiologyoftheCell(©GarlandScience2008) Figure12‐45MolecularBiologyoftheCell(©GarlandScience2008)
DesBnedforERlumen:e.g.,SecretoryProtein
Figure12‐46MolecularBiologyoftheCell(©GarlandScience2008)
IntegralMembraneProtein:SinglePass(w/NTERS)
Figure12‐47MolecularBiologyoftheCell(©GarlandScience2008)
IntegralMembraneProtein:SinglePass(w/oNTERS)
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Figure12‐48MolecularBiologyoftheCell(©GarlandScience2008)
IntegralMembraneProtein:DoublePass(w/oNTERS)
Figure12‐49MolecularBiologyoftheCell(©GarlandScience2008)
IntegralMembraneProtein:MulB‐Pass(w/oNTERS)
Figure12‐50MolecularBiologyoftheCell(©GarlandScience2008)
N‐GlycosylaBon
1. BegininER/finishinGolgi
2. Asn‐X‐Thr(X=Pro)
3. AXachtoaminenitrogenofAsnresidue
4. 90%ofglycoproteins
5. 14sugaroligosaccharide
6. ‐NAGA2‐Man9‐Glu3Figure12‐51MolecularBiologyoftheCell(©GarlandScience2008)
DolicollinkedoligosaccharidetransferredtoAsnresidue
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Figure12‐52MolecularBiologyoftheCell(©GarlandScience2008) Figure12‐53MolecularBiologyoftheCell(©GarlandScience2008)
Calnexin&CalreBculindetectmisfoldedproteinsinER
Figure12‐54MolecularBiologyoftheCell(©GarlandScience2008)
(BIP)
MisfoldedProteinResponse
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MisfoldedProteinResponse
Figure12‐56MolecularBiologyoftheCell(©GarlandScience2008)
GlycosylphosphaBdylinositol(GPI)anchoringoccursintheER
Protein‐CO–O–NH–CH2‐CH2–O–PO2–O–Inositol‐
Figure12‐57MolecularBiologyoftheCell(©GarlandScience2008)
PhospholipidSynthesisOccursonCytosolicSurfaceofERMembrane Phospholipidsare“Flipped”byEnzymes(mostlyABC‐typepumps)
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Figure 13-1 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-2 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-3 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-4 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-5 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-6 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-7a, b Molecular Biology of the Cell (© Garland Science 2008) Figure 13-7c, d Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-8 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-10 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-11 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-12a Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-12b Molecular Biology of the Cell (© Garland Science 2008) Figure 13-13a Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-13b Molecular Biology of the Cell (© Garland Science 2008) Figure 13-13c Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-13d Molecular Biology of the Cell (© Garland Science 2008) Table 13-1 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-14 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-15 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-16 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-17 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-18 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-19a Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-19b Molecular Biology of the Cell (© Garland Science 2008) Page 766 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-20 Molecular Biology of the Cell (© Garland Science 2008) Figure 13-22 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-23a Molecular Biology of the Cell (© Garland Science 2008) Figure 13-23b Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-24a Molecular Biology of the Cell (© Garland Science 2008) Figure 13-24b Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-25a Molecular Biology of the Cell (© Garland Science 2008) Figure 13-25b Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-25c Molecular Biology of the Cell (© Garland Science 2008)
