Evaluation of Articular Cartilage Progenitor Cells for the Repair of Articular Defects in an Equine Model by David D. Frisbie, Helen E. McCarthy, Charles

Evaluation of Articular Cartilage Progenitor Cells for the Repair of Articular Defects in an Equine Model

by David D. Frisbie, Helen E. McCarthy, Charles W. Archer, Myra F. Barrett, and C. Wayne McIlwraith

J Bone Joint Surg AmVolume 97(6):484-493

March 18, 2015

©2015 by The Journal of Bone and Joint Surgery, Inc.

Mean lameness grade (and standard error of the mean) averaged over the study time period (Fig. 1-A) and according to time (Fig. 1-B).

David D. Frisbie et al. J Bone Joint Surg Am 2015;97:484-493


Mean radiographic grade (and standard error) of sclerosis (Fig. 2-A) and central osteophytes (Fig. 2-B) averaged over time.



Mean arthroscopic grade (and standard error) of repair tissue firmness (Fig. 3-A), overall repair tissue grade (Fig. 3-B), and volume of defect filling (Fig. 3-C) estimated at the time of the post

mortem examination.



Representative photomicrographs from the control (Fig. 4-A) and allograft (Fig. 4-B) groups demonstrating increased inflammatory cells in the subchondral bone.



Figs. 5-A and 5-B Cartilage histology at twelve months.



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Evaluation of Articular Cartilage Progenitor Cells for the Repair of Articular Defects in an Equine Model by David D. Frisbie, Helen E. McCarthy, Charles