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Screening Saves Lives! Is Europe ignoring it? Prof Stephen P. Halloran

EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

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Page 1: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Scre

enin

g Sa

ves

Live

s!

Is E

urop

e ig

norin

g it?

Prof

Ste

phen

P. H

allo

ran

Page 2: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Estim

ated

age

-sta

ndar

dise

d ra

tes/1

00,0

00

Men

Wom

en

Wor

ld T

op 2

0 C

ance

rs- G

LOBO

CAN

201

2 (IA

RC)

Inci

denc

e &

Mor

talit

y (2

012)

Wor

ld –

Col

orec

tal C

ance

r●

3rd

com

mon

est c

ance

r•

4nd

caus

e of

Ca

deat

hs W

este

rn E

urop

e•

2nd

com

mon

est c

ance

rde

ath

•2n

d co

mm

ones

t can

cer

1st c

omm

ones

t can

cer

inno

n-sm

okin

g m

en?

Page 3: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Inci

denc

e Mor

talit

y

Estim

ated

age

-sta

ndar

dise

d ra

tes/1

00,0

00

Men

Wom

en

Wes

tern

Eur

ope

Top

20 -

GLO

BOCA

N 2

012

(IARC

)

Inci

denc

e &

Mor

talit

y (2

012)

Wor

ld -

Col

orec

tal C

ance

r●

3rd

com

mon

est c

ance

r•

4nd

caus

e of

Ca

deat

hs W

este

rn E

urop

e•

3nd

com

mon

est c

ance

r•

2nd

com

mon

est c

ance

rde

ath

1st c

omm

ones

t can

cer

inno

n-sm

okin

g m

en?

Page 4: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Tren

ds in

col

orec

tal c

ance

r mor

talit

y in

Eur

ope:

retr

ospe

ctiv

e an

alys

is of

the

WH

O m

orta

lity

data

base

1 in

14

men

1 in

19

wom

enD

iagn

osed

with

col

orec

tal

canc

er d

urin

g th

eir l

ifetim

e

Oua

krim

DA

, Aut

ier

P et

al B

MJ

2015

;351

:h49

70

Col

orec

tal c

ance

r mor

talit

y in

Euro

pe.

Men

& W

omen

- 19

70 a

nd 2

011

1 in

14

men

1 in

19

wom

enD

iagn

osed

with

col

orec

tal

canc

er d

urin

g th

eir l

ifetim

e

(Eur

ope

- 201

2)D

iagn

osed

- 44

7,00

0 p.

a.D

ied

- 215

,000

p.a

.

Page 5: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Surv

ival

- 5

year

s afte

r tre

atm

ent

93 %77 %

7%48 %

>50

year

s old

- 1

in 4

hav

epo

lyps

1 in

10

chan

ge to

inva

sive

canc

er

10 y

ears

Poly

p

Stag

e1

23

4

Col

orec

tal C

ance

rPa

thog

enes

is

Cas

e fo

r Sc

reen

ing

Scre

enin

g C

olon

osco

py –

30

to 4

5 m

ins

•Lo

ok fo

r ca

ncer

s – su

rger

y•

Look

for

poly

ps –

rem

ove

(pol

ypec

tom

y)

Page 6: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells
Page 7: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Col

onos

copy

•Sk

illed

pro

cedu

re -

not w

ithou

t risk

Sele

ct p

atie

nts a

t mos

t risk

of c

ance

r!

Page 8: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Bloo

d in

faec

es…

…st

ill th

e be

st m

arke

rfo

r po

pula

tion

scre

enin

g!

Page 9: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Mr A

lber

t Ein

stein

Pate

nt O

ffice

Bern

Vien

na

FIT

(Fae

cal I

mm

unoc

hem

ical

Tes

t)

One

sam

ple,

Eas

y an

d C

lean

Sens

itive

and

Spe

cific

Gua

iac

Feca

l Occ

ult

Bloo

d Te

st

Thre

e sa

mpl

es, m

essy

,in

terf

eren

ce fr

om m

eat a

ndve

geta

bles

Page 10: EU Presentation March 2016 v2 · Ca s e • 2 nd r ath • 2 nd t r ... Please make Sure you have read the leaflet about bowel cancer screening that we sent to you. The leaflet tells

Euro

pean

gui

delin

es fo

r qua

lity

assu

ranc

e in

colo

rect

al c

ance

r scr

eeni

ng a

nd d

iagn

osis

.C

hapt

er 4

. Fae

cal o

ccul

t blo

od te

stin

g.

Hal

lora

n SP

, Lau

noy

G, Z

appa

MEn

dosc

opy

2012

; 44

(S 0

3):S

E65-

SE87

Rec

omm

enda

tion

Look

sEx

pens

ive?

1st E

ditio

n 20

10