Ethnopharmacological survey of the Bunda district ... · Ethnopharmacological survey of the Bunda district, Tanzania: Plants used to treat infectious diseases ... (Hansel, 1972)

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Journal of Ethnopharmacology 113 (2007) 457–470

Ethnopharmacological survey of the Bunda district, Tanzania:Plants used to treat infectious diseases

Sheila Mgole Maregesi a,b,∗, Olipa David Ngassapa a, Luc Pieters b, Arnold J. Vlietinck b

a Department of Pharmacognosy, School of Pharmacy, Muhimbili University College of Health Sciences, P.O. Box 65013, Dar es Salaam, Tanzaniab Laboratory of Pharmacognosy, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium

Received 8 February 2007; received in revised form 29 May 2007; accepted 1 July 2007Available online 10 July 2007

bstract

An ethnobotanical study was carried out in six villages in the Bunda district, Mara Region, Tanzania, where the use of plants still has a specialeaning to the society, in the treatment of various diseases. Information was obtained from the traditional healers and other experienced persons,

aving some knowledge on medicinal plants. Fifty-two plants were reported for use in the treatment of various infectious diseases. These plantselong to 29 families, with Papilionaceae being the most represented. Leaves ranked the highest, especially for use in topical preparations. Oraldministration was the most frequently used route of administration. Twenty-one percent of the recorded plants were reported for treating venerealiseases, with syphilis and gonorrhea being the most commonly mentioned. Information providers requested feedback with regard to the plantsroven scientifically to be toxic in order to avoid risks while offering their services. From this work it was found out that, people in this area
ommonly use medicinal plants with trust they have built on the curative outcome witnessed. As the first ethnobotanical study in Bunda districtecording 52 plants in a small area covered, publication of this work is expected to open up more studies to record many useful medicinal plantsnfolded.
2007 Elsevier Ireland Ltd. All rights reserved.

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eywords: Medicinal plants; Traditional medicine; Infectious diseases; Bunda,

. Introduction

Plants have always played a major role in the treatmentf human traumas and diseases worldwide (Principe, 1991).hey have been used as sources of drugs employed in modernedicine, either by providing pure compounds, starting mate-

ials for partial synthesis of useful compounds or models forynthesis of new drugs (Hansel, 1972). Folklore informationrom many different cultures is an important tool in revealinglants with useful medicinal properties (Balandrin et al., 1993).ince many clinically useful prescription drugs worldwide haveriginated from the tropical forest, it is worth to embark research-ng on tropical vegetation (Farnsworth et al., 1985) with an
nticipation of obtaining more new bioactive substances. Tanza-ia is located in this zone with a natural forest containing about0,000 species which also carry a very high degree of species
∗ Corresponding author.E-mail address: [email protected] (S.M. Maregesi).

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378-8741/$ – see front matter © 2007 Elsevier Ireland Ltd. All rights reserved.oi:10.1016/j.jep.2007.07.006

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iversity as well as endemicity in the world, as more than 1100pecies are reported to be endemic in this country (Mahunnahnd Mshigeni, 1996).

Few ethnomedical surveys that been carried out in Tanzaniaesulted into compilation of many plants that are used in treat-ng various diseases (Haerdi, 1964; Hedberg and Hedberg, 1982;edberg et al., 1983a, 1983b; Chhabra et al., 1987, 1989, 1990a,990b, 1991, 1993; Ruffo, 1991). The country covers a geo-raphical area of about 945,000 km2 with a population of over0 million, consisting of many ethnic groups. The variable phys-cal features and climatic conditions in different regions providehe country with the richest biological diversity in both flora andauna. Many parts of the country, particularly the remote areasith poor infrastructure have not been reached for the inven-

ory of medicinal plants. These rural communities are almostotally dependent on traditional/herbal medicine for their health
are needs. However, useful information about medicinal plantss still passed from one generation to another by oral commu-ication, posing the danger of loosing some knowledge. Theres, therefore, a need to carry out more research pertaining to
mailto:[email protected]

dx.doi.org/10.1016/j.jep.2007.07.006

458 S.M. Maregesi et al. / Journal of Ethnop

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Fig. 1. Map of Tanzania showing Bunda district.

ocumentation of useful medicinal plants in this country beforehey disappear, especially those which are already endangeredy the arid climatic conditions and man made activities. Agingnd natural death of medicine men (Waganga) are other factorsaving a negative impact on this matter/subject.

The purpose of this survey was to document useful medicinallants with a clearly defined therapeutic context of being used toreat infectious diseases. Although ailments such as convulsions,ypertension, asthma and infertility were beyond the scope ofhe present study, it was considered important to record plantshat were frequently mentioned for the treatment of such healthonditions. In ethnomedical studies, the frequency by which aiven plant is mentioned to be of medicinal value is a goodndicator of its efficacy

The study was conducted in Bunda district located in theavannah grassland, Northern part of Tanzania (Fig. 1).

. Methodology

The survey was carried out for a period of 28 days inuly, 2000, in six villages located in Bunda district. Theillages included Bitaraguru, Kung’ombe, Nyasana, Kabasa,amukenga and Kangetutya. The interview was conductedsing national language, Kiswahili, and sometimes it was nec-ssary to combine with local dialects to enable the informantso give correct information with ease. This was possible, sincene of us (SMM) speaks those dialects fluently. There were aotal of 10 informants, two of them were traditional healers andhe rest were family members and other individuals who gainednowledge on medicinal uses of plants, from their parents orelatives and had used the plants with promising results.

Interviews and fieldwork were done on alternate days. Thenterviews were in the form of group discussions, in groups ofhree or four people, except for the traditional healers who pre-erred confidentiality. Information was sought concerning their

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harmacology 113 (2007) 457–470

nowledge about infectious diseases, local names of plants usedn the treatment of the mentioned ailments, plant parts, meth-ds of preparation, dosage, duration of use and any specialondition/information about the drug. The information aboutach particular plant was then immediately recorded on a ques-ionnaire (see Appendix A). During fieldwork plant materialsere collected for preparation of herbarium specimens and

or biological testing. The plants were identified by Mr. Frankbago, of the Herbarium Unit, Botany Department of the Uni-

ersity of Dar es Salaam, by comparison with the herbariumpecimens. Voucher specimens were deposited in the sameerbarium.

. Results and discussion

.1. Information providers and criterion of plant selection

There were a total of 10 informants, all of them had the pri-ary school education, except two. The informants’ attitudeas positive with regard to providing useful information, how-

ver, it was necessary to pay some money, as an incentive forhe information they provided. Medicinal plants reported in thisrticle are those mentioned by at least five informants, except forarleria eranthemoides R.Br. that was collected due to empha-is of a traditional healer that it is a useful herb for severalnfectious diseases and that he obtained curing outcome(s). Therequency of mention is indicated in Table 1. The general con-ept of infectious diseases was clear to them that, such diseasesere caused by very tiny organisms invisible with naked eyes.hey referred to those tiny organisms as “Tuvidudu”, meaningery tiny insects/organisms. In a very simple language someould differentiate disease conditions of a particular organ. Forxample for the stomach, the illness could be due to overeatingr indigestion, food poisoning or contamination, and surgicalroblems, which they said were far beyond their limits. Skinroblems were classified in two types: the infectious type, suchs boils, athlete’s foot and cellulites, and inborn illnesses suchs allergic conditions.

.2. Plant families, plant parts and local names

The study has identified 52 plants belonging to 29 fami-ies, which are used in the treatment of infectious diseases ashown in Table 1. Of these families, Papilionaceae was theost represented (27.59%) followed by Compositae (13.79%)

nd Anacardiaceae, Labiatae and Mimosaceae (10.34%) each.thers represented by either 6.90 or 3.45%.During plant collection, it was observed that some plants

ad more than one vernacular name due to the different localialects used in the area. The medicinal use of certain plantsr plant parts were commonly mentioned by informants. Thus,n some cases, especially shrubs and trees, the whole plant had

edicinal application.
Leaves were the most frequently used plant parts, espe-
ially for topical application, constituting 38.6%, followed byoots (28.6%), stems (20%), whole plant (10%) and fruit/seeds2.8%).

S.M. Maregesi et al. / Journal of Ethnopharmacology 113 (2007) 457–470 459

Table 1Plants used to treat infections in Bunda district

Plant name (family, Latin,binomial and voucherspecimen number)

Frequency ofmention

Vernacular name(s) Medicinal traditional uses Some previous report(s) onethnomedical/botanical uses

Acanthaceae, Barleriaeranthemoides R. Br.,SMM-BD23

1 Sese yahase (Sukuma) Roots decoction or infusionof pounded leaves is drunkfor treatment of dysentery.According to the traditionalhealer, the plant is very potentfor several infectious diseases

The plant is used for humanmedicine in the Gash-Barkaregion, Eritrea (Ogbazghi andBein, 2006)

Acanthaceae, Blepharispanduriformis Lindau,SMM-BD38

5 Mukilabaigi (Jita) Whole plant is boiled inwater, decoction drunk fordysentery

No report has been found

Aizoaceae, Zaleya pentandra (L)Jeffrey, SMM-BD25

5 Isindura (Jita & Ruri),Kaitongo (Sukuma)

The whole plant is dried,powdered and applied directlyon Athelete’s foot and veryseptic wounds. Roots arechewed with Voandzeiasubterranea Thou. (njugumawe (Swahili)) to shortenlabour pains during delivery

Roots: wounds, stomach pain,diarrhoea, dysmenorrhoea,polymenorrhoea. Leaves:colds. (Samuelsson et al.,1991). Plant decoction:abortifacient and againststomach troubles (Saha et al.,1961; Farouk et al., 1983)

Anacardiaceae, Lannea humilis(Oliv.) Engl. SMM-BD34

6 Nyamunogo (Jita) Roots are boiled in water,decoction is drunk foranaemia and stomach pains

Roots: nausea and generalbody weakness (Kokwaro,1976)

Anacardiaceae, Lanneaschweinfurthii (Engl.) Engl,SMM-BD01

7 Lisalwa (Jita) Stem bark is boiled in waterand drunk for treatment ofsyphilis, cellulitis, abscessesand oral candidiasis

Bark decoction: gingivitis,root decoction: nasal ulcersand asthma. (Neuwinger,2000)

Anacardiaceae, Ozoroa reticulata(Bak.f.) R.A. SMM-BD22

5 Nago (Sukuma) Decoction of either roots orstem barks is drunk fortreating dysentery, choleraand anaemia. Root or stembarks boiled in water withsugar is taken orally fortreatment of hypertension

Stem bark decoction:diarrhoea and stomach pain(Kokwaro, 1976), dysentery(Watt and Breyer-Brandwijk,1962). Root decoction:bilharzia (Hedberg andHedberg, 1982), malaria andaphrodisiac (Haerdi, 1964).Root and stem barks: vaginaland oral candidiasis (Runyoroet al., 2006)

Balanitaceae, Balanitesaegyptiaca (L.) Del.,SMM-BD27

8 Liluguyu (Jita) The stem bark is macerated inwarm water, the extract drunkfor treating asthma, drycough and chest infection

Plant: antiparastic,antipyretic, fish poison,abortifacient andmolluscicidal (Iwu, 1993)

Bignoniaceae, Kigelia africana(Lam.) Benth, SMM-BD03

5 Lisamwa (Jita), Ng’wicha(Sukuma)

Stem bark is boiled in waterand drunk for treatment ofpneumonia, gonorrhea,bilharzia, dysentery,coughing, and femalegynaecological problems.The fruit is boiled and takenorally for treatment ofaneamia especially withpregnant women

Roots: malaria, syphilis andsnakebite. Stem: stomachpain, gonorrhoea, trachoma,burns and worms (Kokwaro,1976). Stem bark decoction:measles, analgesic and fever(Kamuhabwa et al., 2000).Inner stem bark: dysentery,constipation, wound dressingand boils (Irvine, 1961)

Boraginaceae, Trichodesmazeylanicum (L.) R. Br.,SMM-BD41

6 Nyabugimbi (Jita) Roots are boiled in water,decoction drunk and douchedfor treatment of vaginitis.Leaf infusion is used as eyedrop for treatment of cataract

Roots: wounds and analgesic.Plant: snakebite antidote anddiuretic (Watt andBreyer-Brandwijk, 1962).Leaves: fevers, scorpion biteand analgesic (Iwu, 1993)

460 S.M. Maregesi et al. / Journal of Ethnopharmacology 113 (2007) 457–470

Table 1 (Continued )


Frequency ofmention


Caesalpiniaceae, Senna siamea(Lam.) Irwin & Barneby,SMM-BD32

10 Masongoma (Jita, Sukuma),Mijohoro (Swahili)

Roots are peeled, poundedand boiled, the decoction isdrunk for treating gonorrhea

Roots decoction or infusion:malaria (Macfoy and Sama,1983), decoction: hernia(Chhabra et al., 1987). Freshroots decoction with lemon: feverand jaundice (Adjanohoun et al.,1986)

Capparidaceae, Bosciaangustifolia R. Br.,SMM-BD26

5 Lisingisi (Jita) The stem bark is boiled inwater and drunk for treatmentof mumps, dysentery andvenereal diseases

Bark decoction: malaria(Kokwaro, 1976). Plant:psychiatric and psychosomaticdisorders (Mathias, 1982; Iwu,1993)

Capparidaceae, Maerua edulis(Gilg &Bened.) De Wolf,SMM-BD14

10 Manywera manji (Kurya),Manywera (Jita)

The peeled roots infusion istaken orally for treatingvenereal diseases especiallygonorrhea and syphilis. Rootsare eaten during foodshortages. The plant ispoisonous, death occurs wheneaten in excess

Roots: gonorrhoea, syphilis andeye infection, Fruit and leaves:applied topically against pain andrheumatic swellings. Raw rootinduces thirst and is poisonous(Kokwaro, 1976)

Celastraceae, Elaeodendronschlechteranum (Loes.) Loes,SMM-BD16

8 Chihusilo (Jita), Ngakama(Sukuma)

The powder of root/stembarks is applied directly onfoul smelling septic wounds.Stem bark is boiled in waterto give a tonic used to treatanaemia and hypertension.Root bark decoction is drunkto treat dysmenorrhoea,female infertility, and maleimpotence

Roots: abscesses and carbuncles(Watt and Breyer-Brandwijk,1962; Khan et al., 1980)

Chenopodiaceae, Chenopodiumambrosioides L., SMM-BD36

6 Injaga-yabekwabi (Jita),Nemu ya Masai (Sukuma)

The shoot is ground, soakedin warm water, extract isgurgled for oral thrush, drunkand douched for vaginalulcers. The powder issprinkled on boils. Leaves aresoaked and drunk to expeltapeworm

Leaves: various advanced cancersincluding that of kidney,antihelminthic for humans andanimals, antidiabetic, antiamoeba(Azuine, 1998), menstrualdisorders and dysmenorrhea(Ososki et al., 2002). Aerial part:stomach, bile and vesiculardisorders (Macia et al., 2005)

Chenopodiaceae, Chenopodiumopulifolium Koch & Ziz,SMM-BD33

5 Mogabhogole (Jita) Leaves/shoot are dried,powdered and appliedtopically on fungal/bacterialscalp infection. Sometimes itis mixed with soda ash

Leaves: eye ointment. (Watt andBreyer-Brandwijk, 1962). Leafmaceration: female asthenia anddiluted leaf sap: abdominal colicfor newborns (Adjanohoun et al.,1993). Root decoction: inducingmensutration and hasten birth(Chhabra et al., 1989)

Combretaceae, Combretumadenogonium Steud exA.Rich., SMM-BD18

7 Malangu (Jita), Nonja minzeor Makoyoyo (Sukuma)

Powdered leaves or stem barkis sprinkled on septic woundsand fungal infection of thescalp

Roots decoction: coughs andsyphilis (Kokwaro, 1976),leprosy (Chhabra et al., 1989).Root infusion: an aphrodisiac(Gelfand et al., 1985). Leafdecoction used to clean chronicwounds (Adjanohoun et al.,1986). Sap from chewed leavesand shoot is swallowed and pulpis applied on snakebite (Imperato,1977)




Frequency ofmention


Combretaceae, Terminalia mollisLaws, SMM-BD06

8 Linyago (Jita) Root bark decoction drunkagainst urine-blockage,kidney problems, diarrhoea,and dysentery. Stem barkdecoction is drunk forjaundice treatment, andinfusion is applied as dropsfor eye infection

Bark powder: wounds,haemorrhoids and used ashaemostatic. Leafextract/decoction: diarrhoea andas enema (Neuwinger, 2000)

Compositae, Emilia coccinea(Sims) Sweet, SMM-BD49

5 – Infusion from whole plant isdrunk for treatment of cancer

Root decoction: syphilis, leaves:nose infection, sores and as apoultice (Kokwaro, 1976), earinfection (Tabuti et al., 2003),threatened abortion, cardiac andovarian problems, splenomegaly,ulcers, abscess and childrenepilepsy/convulsions(Neuwinger, 2000)

Compositae, Felicia grantii (Oliv.& Hiern) Grau, SMM-BD45

5 Nyaseko-indume (Jita) Plant sap is used against eyeinfection. Roots decoction isdrunk for stomach pains

Plant decoction: insanity, andplant sap: eye problems(Neuwinger, 2000)

Compositae, Senecio discifoliusOliv. SMM-BD09

5 Imangwe (Ruri) Decoction of the whole plantis drunk for treatment ofsyphilis, the preparation issaid to be more effectivewhen combined withHarrisonia abyssinica Oliv

Plant decoction: stomachacheduring pregnancy, andstimulation of milk productionafter birth. Leaves: sore eyes.(Kokwaro, 1976)

Compositae, Tithonia diversifolia(Hemsl.) A.Gray, SMM-BD30

10 Maua (Swahili, Sukuma) Pounded fresh leaves aresoaked in water and bathedfor skin infections. While theconcentrated macerate isdrunk for stomach problems

Leaf infusion: abdominal pains,indigestion, sore throat, and liverpain (Kokwaro, 1976). Leafmaceration: amoebic dysentery(Tona et al., 1998)

Compositae, Vernoniacinerascens Sch. Bip.,SMM-BD05

5 Mbalike (Sukuma) Leaves boiled and bathed forskin infection, Steam isinhaled for mental disorderstreatment

Young twigs, leaves and roots:depression (Von Koenen, 2001)

Euphorbiaceae, Euphorbiaheterophylla L., SMM-BD39

5 Nyamata (Jita) Whole plant is boiled inwater, decoction drunk fortyphoid fever

Plant: antidote for irritationproduced by other species ofEuphorbia (Watt andBreyer-Brandwijk, 1962)

Euphorbiaceae, Euphorbiatirucalli L., SMM-BD43

10 Minyaa (Swahili),Masongorwa (Jita, Sukuma)

Latex is applied into the eyesfor ophthalmic infections.Root decoction is drunk totreat gonorrhea and syphilis.Sometimes the preparation isdone by a combination ofSenna siamea (Lam.) Irwin &Barneby

Young branches: sore throat, andstomach complain. Roots: emeticfor snakebite, women sterilityand the plant is toxic (Kokwaro,1976). Root and leaf extracts:syphilis and malaria, respectively(Rwangabo, 1993)

Fabaceae, Crotalaria cf. CaudataWelw. ex Baker., SMM-BD17

5 Bulebasubhugu (Jita),Kaninagu (Sukuma)

Powdered leaves is mixedwith fats or oils is appliedtopically to treat skindiseases. Leaf decoction isdrunk to treat of gonorrheaand threatened miscarriage

Leaf infusion: insanity (Baertsand Lehmann, 1989)

Fabaceae, Crotalaria retusa L,SMM-BD50

6 Ganyabhundege (Jita) Leaf juice used as dropsagainst eye infection, whilethe leaf infusion is bathed forskin diseases

Leaves: fever and skin diseases,roots: haemoptysis and colic.Seeds are toxic (Nobre et al.,2005), Fresh roots paste: appliedon wounds (Samuelsson et al.,1992)




Frequency ofmention


Labiatae, Hoslundia oppositaVahl, SMM-BD31

6 Omunyenyete (Kurya) Ground fresh leaves aresoaked in water the extractdouched to treat vaginitis,drunk for treatment ofhypertension. The roots areboiled and taken orally tocure children fever andconvulsions

Leaves: skin diseases and herpeszoster, whole plant: liver cancer(Azuine, 1998). The plant:gonnorrhoea, blenorrhoeacystitis, liver disease, chest pain,cough, fever, hookworm,stomach disorders, wounds andmental distarbances (Watt andBreyer-Brandwijk, 1962), Roots:treatment of malaria (Haerdi,1964), epilepsy and convulsions,measles like swellings on the skin(Hedberg et al., 1983a)

Labiatae, Leonotis nepetifolia L.,SMM-BD40

6 Gabunyunywa (Jita) Juice from fresh groundleaves or dry powder isapplied fresh or septicwounds, leaves are boiled andthe decoction is drunk fortreatment of convulsions

The whole plant: fever,headaches elephantiasis, andamenorrhoea. Leaves: malaria,typhoid, syphilitic ulcers asthmaand as haemostatic (Watt andBreyer-Brandwijk, 1962). Aerialparts decoction: fever(Rasoanaivo et al., 1992)

Labiatae, Plectranthuskilimandschari Gurke,SMM-BD47

9 Makoroma (Jita), The leaf infusion drunk forchest pain, cough,dysmenorrhea and dysentery

Leaves are boiled in water andinhaled for psychiatric problems(Chhabra et al., 1990a). Leaves:phagedenic ulcers (Rwangabo,1993)

Mimosaceae, Acacia brevispicaHarms, SMM-BD19

5 Bigeye (Jita), Lugeye(Sukuma)

Pounded leaves is rubbed onthe infected swollen part ofthe body or dressed on theabscess. Leaf infusion isoccasionally drunk for thesame ailments

Roots: cough (Chhabra et al.,1990b), snake bites, femaleinfertility, antihelminthic,aphrodisiac (Kokwaro, 1976)

Mimosaceae, Acacia tortilis(Forsk.) Hyne, SMM-BD29

5 Ng’ale (Sukuma) Stem bark is pounded andsoaked in water, the extractgurgled to treat mouthinfections and dentalproblems

Root: correction of irregularmenses. (Chhabra et al., 1990b).Dried root maceration is drunkfor malaria treatment (N’Diaye,1962)

Mimosacea, Dichrostachyscinerea (L.) Wight & Arn,SMM-BD44

7 Bisanjawe (Jita) Roots are boiled in water anddrunk for treating venerealdiseases. Leaves are chewedand swallowed for snakebiteantidote

Roots: pulmonary tuberculosis,antiseptic and wounds (Watt andBreyer-Brandwijk, 1962),syphilis and leprosy. Stem bark:dysentery and worms, leaves:gonorrhoae, urethral discharge,sore throat, inflammatoryswelling, abscesses, andelephantiasis (Azuine, 1998).Fruits: venereal disease (Kambiziand Afolayan, 2001). Analgesic,antiasthma and antiviral (Iwu,1993; Kamuhabwa et al., 2000)

Moraceae, Ficus sycomorus L.,SMM-BD21

5 Likuyu (Jita), Nkuyu(Sukuma)

Stem bark is boiled in waterand drunk for treatment offungal infection of the gut,abscess, boils, peptic ulcersan jaundice. The same isdouched for treatingvaginal/anal infections

Plant: respiratory disorders andcertain skin diseases (Mousa etal., 1994). Fruits: eaten toencounter stomach pain (Lockettand Grivetti, 2000), fruitinfusion: against tuberculosis(Arnold and Gulumian, 1984)




Frequency ofmention


Nyctaginaceae, Boerhaviacoccinea Mil, SMM-BD46

6 Likukubi (Jita) Leaf infusion is gurgled fororal candidiasis and apthousulcers. Root decoction istaken orally for the sameailments

Plant: gastrointestinal infections(Tapia-Perez et al., 2003), rootand leaves: liver problems andtoothache, respectively(Neuwinger, 2000)

Oleaceae, Jasminum fluminenseVell., SMM-BD15

7 Binyafwira (Jita) Fresh leaves are pounded togive a paste dressed on theaffected area to treat cellulites(termed wild abscess) andabscess. Leaves macerated incold water and drunk to treatfemale infertility

Roots: snakebite antidote (Wattand Breyer-Brandwijk, 1962;Kokwaro, 1976) and uvulitis,Leaves: as antihelminthic inchildren, (Chhabra et al., 1990b),antirheumatic and antidiarrhoea(Haerdi, 1964)

Papavaraceae, Argemonemexicana L., SMM-BD12

10 Rangiibili (Sukuma),Rikararungu (Kurya)

The juice (latex) fromdifferent parts of the shoot isapplied directly on woundsand sores. Crushed leaves aresoaked in cold water andbathed for treating skininfections

Whole plant: skin cancer, latex:warts and chancres, roots:inflammatory swelling andtoothache, tapeworm, boils andabscesses (Azuine, 1998). Plantsap used for treatment of wartsand ulcers (Amico, 1977)

Papilionaceae, Dalbergiamelanoxylon Guill & Perr,SMM-BD20

6 Echigembe (Jita), Gembe(Sukuma), Mpingo (Swahili)

Decoction of the leaves isdrunk for abscess and otherswollen parts due toinfections, the poundedleaves are used to massageswollen parts

Roots: abdominal pain, hernia,uterine prolapse, dysuria,hiccups, impotence, and asaphrodisiac (Chhabra et al.,1990b), headaches and bronchitis(Kerharo and Adam, 1974).Leaves: throat inflammation,cardiac problems, amoebicdysentery, and syphilis (Haerdi,1964), joint pains (Kokwaro,1976)

Papilionaceae, Aeschynonemeindica L, SMM-BD 51

5 – Leaf or root infusion drunkfor treatment of jaundice

Plant used as antifertility drug,the in vitro test was positive inmale human and rat semens(Oliver-Bever, 1986)

Papilionaceae, Erythrinaabyssinica Lam, SMM-BD02

5 Liebhete (Jita) Stem bark and roots areboiled the decoction is drunkfor curing diarrhoeadysentery and jaundice

Roots infusion: venereal diseases(Kambizi and Afolayan, 2001),jaundice, leprosy, rheumatism,dysentery, and beriberi,bronchitis, pneumonia and fever(Azuine, 1998). Stem bark:stomachaches (Chhabra et al.,1990b). Root bark/root:trachoma, gonorrhoea, abdominalpains, burns, general bodyswelling and antihelminthic,malaria syphilis and snakebites(Kokwaro, 1976)

Papilionacea, Indigofera colutea(Burm.f.) Merr, SMM-BD24

5 Nengo yahase (Sukuma) The whole plant is poundedand soaked in warm water.The extract is used to cleanmultiple boils while part ofthe extract is concentrated byboiling and taken orally fortreating the same problem

Pounded root mixed with ghee isapplied on cuts and bruises. Theplant is rubbed in against scabies(Neuwinger, 2000)

Papilionacea, Lonchocarpuseriocalyx Harms, SMM-BD28

6 Lijare (Jita), Mutungutu(Zanaki)

Stem bark is boiled in water,decoction drunk to treatcough, stomach pain anddysentery

Root powder: pimples (Kokwaro,1976), skin-eruptions (Watt andBreyer-Brandwijk, 1962)




Frequency ofmention


Papilionaceae, Ormocarpumkirkii S. Moore, SMM-BD13

7 Mtemanjofu (Jita) Roots and leaves are used fortreatment of abscess andcellulites. Roots are boiled inwater and drunk, fresh leavesare pound, little water addedto make a paste used fordressing the affected area.Root decoction is drunkagainst fever

Whole plant: oedema, roots:rheumatism and stomach pains,(Kokwaro, 1976). epilepsy andhernia, root bark and stem barkfor diarrhoea and headache,respectively (Chhabra et al.,1990b)

Papilionaceae, Rhynchosiasublobata (Schum.) Meikle,SMM-BD07

8 Nyakasorogo (Jita) The root is ground andsoaked in warm water, theinfusion is drunk fortreatment of blood diarrhoea

Leaf sap and root decoction:tachycardia and gall bladderdisorders in children (Haerdi,1964). Leaves: stomachproblems, roots: chest illness,antidote for snakebite. (Kokwaro,1976)

Papilionaceae, Sesbania sesban(L) M.S., SMM-BD49

10 Zuzuma (Sukuma) Pounded fresh leaves soakedin cold or warm water, theinfusion taken orally fortreatment of venereal diseases

Plant: throat sore, gonorrhoea,syphilis, yaws, childrenconvulsions and as insecticide.Leaves: leprosy (Chhabra et al.,1990b), swelling and stomachtroubles (Kokwaro, 1976), root:dizziness and as antihelminthic(Haerdi, 1964), scorpion bite,guinea worm. Seed powder:applied topically, barks juicetaken orally for skin itch. Seedsused for bronchial catarrh andexcessive mensentralhaemorrhage (Watt andBreyer-Brandwijk, 1962)

Polygonaceae, Rumexusambarensis (Dammer)Dammer, SMM-BD42

5 Binyambe (Jita) The shoot is pounded, soakedin hot water, the infusiondrunk for treatment ofhaemorrhoids. Leaves arewrapped in banana leaf,warmed and squeezed to givethe juice applied through thenose to treat tonsillitis

Roots: bilharzia (Hedberg et al.,1983b), young stem: pepticulcers, diarrhoea and vomiting(de Boer et al., 2005). Leaves:diabetes (Chhabra et al., 1991),stomach pain and cough. Thewhole plant: smallpox (Kokwaro,1976)

Rubiaceae, Crossopteryxfebrifuga (G. Don) Benth.,SMM-BD11

5 Kumbwambizo (Sukuma) Root bark is boiled in water,the decoction taken orally fortreatment of tuberculosis andvenereal diseases. Rootdecoction is used cure femaleinfertility

Roots: tuberculosis, cough,spasm of the stomach andhookworm (Haerdi, 1964),syphilitic ulcers (Watt andBreyer-Brandwijk, 1962).Fermented leaves: conjunctivitis,root decoction: venereal diseases(Kokwaro, 1976)

Sapindaceae, Cardiospermumhalicacabum L., SMM-BD08

6 Nyamtumuka (Jita) The leaves or shoot systemare ground and mixed withfats, the paste is used fordressing the abscess. Seedsare powdered for treatment ofseptic wounds

Leaves: purgitive (Natarajani etal., 1999), piles, digestive andpulmonary disorders, diarrhoea,dysentery, syphillis, andrheumatism, (Watt andBreyer-Brandwijk, 1962).Swelling, skin eruptions, itch,etc. Stem juice: for opththlamia.Seeds induce epiletiformconvulsion in children(Oliver-Bever, 1986). Leaves androots: nervous disorders (Watt,1967)




Frequency ofmention


Scrophulariaceae, Buchneraspeciosa Skan, SMM-BD37

5 Ifufya (Jita), Kidua (Swahili) Roots are pounded andmacerated in water, theextract is gurgled for dentalproblems. The root is alsoused as a toothbrush

No report has been found.

Simaroubaceae, Harrisoniaabyssinica Oliv., SMM-BD10

10 Lisawa (Jita) Peeled roots are boiled inwater, the decoction is drunkfor treatment of fever,malaria, diarrhoea andabscess

Roots decoction: epilepsy (Moshiet al., 2005), abscesses,dysmenorrheoea, malaria and asvermifuge against ascaris(Haerdi, 1964). Fever, Insomnia,nausea, vomiting, bubonicplague, testicles swelling andtuberculosis (Kokwaro, 1976).Fever, dyspepsia, and cancer(Kamuhabwa et al., 2000)

Solanaceae, Withania somnifera(L.) Dunal, SMM-BD35

5 Lifubefube (Jita) The roots are used for treatingconvulsions in children. Rootdecoction is drunk andpounded roots is mixed withoil or fats and smeared allover the body during theattack. Root powder issprinkled on the nipples toenable babies take it whilebreast-feeding

Leaves: breast cancer, infusiontaken orally as antibiotics againstbroad-spectrum bacteria andvirus (Azuine, 1998). Both leavesand roots taken internally, andfresh-pounded leaves appliedexternally against fever, chills,rheumatism and colics(Oliver-Bever, 1986). Leaves:otitis insanity, and skin diseases,(Baerts and Lehmann, 1989)

Sterculiaceae, Waltheria indicaL, SMM-BD04

5 Ngung’u (Sukuma), Echumya(Ruri), Mkama-werungu(Jita)

Powdered leaves aresprinkled on fresh septicwounds. Whole plant isboiled and drunk fortreatment of dysentery andtaken as an antidote ofpoisoning

Leaves: blood diarrhoea (Chhabraet al., 1993), convulsions andwounds (Hedberg et al., 1983b).Roots: syphilis (Haerdi, 1964,Kokwaro, 1976)

Verbenaceae, Stachytarphetajamaicensis (L.) Vahl,SMM-BD52

5 – The fresh leaves are groundand juice applied to treatfungal infections of the nails

Leaves: snake and insect bites(Natarajani et al., 1999),headache (Kokwaro, 1976).

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.3. Dosage forms and routes of administration

Dosage forms included liquid preparations (decoctions, infu-ions or macerates), juices obtained by steaming or crushinghe plant material followed by squeezing and latex. Solidreparations included dry powdered materials and soft pastsade in fat/oils or water. Most of the preparations were

aken orally, while topical application was mainly used forounds and other skin infections. Other routes of adminis-

ration included inhalation of steam from hot, water-boiledreparations, douching or bathing with macerates, infusions orecoctions. In most cases, the use of a given drug preparationas continued up to at least three days after a symptomatic

elief was achieved. This was especially the case for oral
osage forms, to make sure that the infection was cleared.wenty-one percent of the plants were reported for the
reatment of venereal diseases with gonorrhea and syphiliseing frequently mentioned. About 19% of the plants were

tuir

Plant: used to treat tumors(Ososki et al., 2002)

sed for dysentery and diarrhea, and 15% for skin prob-ems.

.4. Plants with scarce documentation on medicinal use

To the best of our knowledge, this is the first documentationf the medicinal applications of Buchnera speciosa Skan andlepharis panduriformis Lindau. Recently the medicinal use ofarleria eranthemoides R.Br. for human purposes in the Gash-arka region, Eritrea has been reported, however, no detailed

nformation such as how and for what disease was describedOgbazghi and Bein, 2006). The scanty distribution, small sizend thorny nature of Barleria eranthemoides could hardly attractts collection for random screening. It happened to be among
hose plants documented in our study with some medicinalses giving a credit to plant collection based on ethnobotan-cal/ethnomedical data. Reluctance of a traditional healer toeveal all information pertaining to the medicinal application

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66 S.M. Maregesi et al. / Journal of E

f Barleria eranthemoides augumented with the then, lack ofocumented data triggered our interest to search therapeuticallaims of other plants belonging to the same genus. Those havingedicinal application include Barleria lupulina, used in India

or treatment of various ailments including mental illness, fever,ain and diabetes, and as diuretic (Chopra et al., 1968). Phar-acological/biological activities of the Barleria genus include

nti-diabetic activity (Barleria lupulina, Barleria cristata, andarleria prionitis) (Rahman and Zaman, 1989; Suba et al.,004), anti-HSV-2 (Yoosook et al., 1999; Yoosook et al., 2000)nd anti-inflammatory activity (Barleria lupulina and Barleriarionitis) (Singh et al., 2003; Suba et al., 2005). Antifertility andentral nervous system activities have been observed in animalodels for Barleria prionitis and Barleria lupulina, respectively

Gupta et al., 2000; Suba et al., 2002; Verma et al., 2005). Fur-her research on Barleria eranthemoides will reveal its medicinalotential and facilitate its use as a standardized herbal drug.

.5. Common plants in the area with previous medicinaleports

The Combretaceae is a large family with at least 600 species,nd its commonly occurring genera Terminalia and Combretumith 250 species each are widely used in African traditionaledicine. Previous studies had confirmed antimicrobial activity

rom extracts/isolated compounds of some species belonging tohis family (Baba-Mousa et al., 1999; Fyhrquist et al., 2002;aterere et al., 2003; Martini et al., 2004). Terminalia mollis

nd Combretum adenogonium were noted as common medicinallants in the study area, these are among the evergreens of theavannah grassland. Their survival is in part due to possessionf fire resistance. In case proven medically useful the supplyill not pose a problem of availability. Currently, these plants

re mainly used to provide wood for fuel and construction inhat area.

Two traditional healers highly trusted in the area confi-ently reported with emphasis to use Crossopteryx febrifugand Ozoroa reticulata to cure confirmed cases of tuberculo-is and cholera respectively. The use of Crossopteryx febrifugas antitubercular had previously been reported (Haerdi, 1964).uberculosis is among the infectious disease currently facing

reatment problems due to the emerging of new multidrug resis-ance strains (Centers for disease Control, 1991). This creates aeed of searching new antituberculosis drugs. The antimicrobialesting is essential to prove such claims and if true to carry outurther steps of isolating bioactive principle(s).

Another interesting observation is that certain plants such asichrostacys cinerea used in Tanzania for treatment of venerealiseases, are also reported to be used in other parts of Africa forhe same purpose (Azuine, 1998; Kambizi and Afolayan, 2001).rythrina abyssinica Lam. used against diarrhoea, dysentery and

aundice, and its taxonomically related species, Erythrina sene-alensis DC, Erythrina vogelii Hook. F., Erythrina excelsa Bak.,
rythrina sigmoidea Hua and Erythrina mildbraedii Harmsre chiefly are used for the treatment of jaundice and gonnor-heoa in Nigeria and dysentery in Ghana (Oliver-Bever, 1986).urthermore, Erythrina senegalensis DC has shown antibacte-
Ttpm

harmacology 113 (2007) 457–470

ial activity against Pseudomonas aeruginosa, Staphylococcusureus and Escherichia coli (Adamu et al., 2005). Relatedr identical bioactive principles may account for their similaredicinal applications mentioned in different places.

.6. Feedback of scientific findings to information providers

It is unfortunate that very few scientific findings are reportedack to traditional healers due to the fact that scientific articlesre inaccessible and incomprehensible to them (Jager, 2005).

hile conducting this study, some informants raised some con-ern on false promises about getting the feedback. They agreedhat scientific methods are better in revealing harmful effectsf herbs, if any. Although scientific results are far beyond theirnderstanding and interpretation, some information especiallybout poisonous plants is worthwhile knowing since their inten-ion is to cure and not kill or produce other diseases. A goodxample of a toxic plant recorded in this study is Euphorbia tiru-alli L. widely used in tropical Africa, Asia, and Latin America.ts ethnomedical uses appear in many published articles and areell outlined by Neuwinger (2000) and Taylor (2005). Phyto-

hemical studies have revealed that it contains many harmfulompounds that make it unsuitable for many claimed medic-nal uses especially for cancer treatment. The latex is rich inerpenes including phorbol esters and ingenol esters. These phor-ol esters are highly irritating, and clinical studies have shownhem to be co-carcinogens (Aya et al., 1991; MacNeil et al.,003). Other actions include suppression of the immune system,arcinogenicity, and caustic activity (Imai et al., 1994; Taylor,005).

In the drug development research, biological activity basedn ethnomedical uses seems as a better approach compared toandomly selected plants (Cordell, 1995; Unander et al., 1995).f this is true, there is a need to send back useful findings tonformation providers at the level of their understanding andractices in order to reduce health hazards that might be anutcome of the treatment offered by them.

We are currently testing these plants for antibacterial, antifun-al, antiparasitic, antiviral and cytotoxic activities to confirm theherapeutical claims indicated by informants. Any useful infor-

ation from literature review and biological tests will be passedack in order to improve the proper use of medicinal plants andreate a good relationship for future ethnobotanical studies.

. Conclusion

Modern health care services provided in Bunda district areare not adequate, since the health care centers/hospitals areew and sometimes distantly located, and most people cannotfford to buy drugs prescribed due their low income. Tra-itional/herbal medicine keeps working as the most popularomplementary/alternative medicine in solving health problemsn the area, and people have strong trust in the efficacy of herbs.
hey believe in what they see, to them what matters is to have
he correct diagnosis by the healer and get the right drug toroduce a desirable outcome just as it is the case in modernedicine. Most of the recorded plants are also used in other

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S.M. Maregesi et al. / Journal of Et

frican countries where traditional medicine still contributes toealth care services. This indicates the medicinal potential ofhese plants since nobody could be willing to use medicine(s)hat do not offer healing result(s). If these drugs in their crudeorms have curative properties in societies using them, scientifictudies could lead to isolation of active principles or compoundshat can serve as templates for the synthesis of modern drugs, orreparation of standardized herbal products.

Due to limited resources, only six villages were visited and itas noted that some plants were not readily available due to dryeather conditions during the study period. It is recommended

hat future work in this locality should be carried out immedi-
tely after the rainy season for one to be able to record a largeumber of medicinally useful plants, especially the annual herbs.eam-work consisting of a good number of pharmacognosists,
Ew

A

harmacology 113 (2007) 457–470 467

botanists/taxonomists and medical doctors is recommendedor any future ethnobotanical surveys, in order to have broadcope of study leading to a rich documentation of medicinallants in this area.

cknowledgements

This work was funded by Muhimbili University College ofealth Sciences through the Directorate of Postgraduate Studies.e are very grateful to all the people who provided information

n medicinal plants in the six villages of Bunda district andsther Nyakwesi (SMM’s mother) for her contribution to thisork.

ppendix A. Questionnaire

4 thnopharmacology 113 (2007) 457–470

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B


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Documents

Ethnopharmacological survey of the Bunda district ... · Ethnopharmacological survey of the Bunda district, Tanzania: Plants used to treat infectious diseases ... (Hansel, 1972)