ESUCB 2013

European Symposium on Ultrasonic Characterization of Bone Granada, 7-10 May 2013

www.ugr.es/~esucb2013

Local organiser: Guillermo Rus Carlborg ETSICCP, University of Granada grus@ugr.es www.ugr.es/~grus

2

Welcome The 5th European Symposium on Ultrasonic Characterization of Bone (ESUCB 2013) will be organized at the University of Granada, Spain, within the Nondestructive Evaluation Lab, Dept. of Structural Mechanics. The Symposium is a continuation of four previous meetings, initially organized by the French-German network on ultrasound assessment of bone strength from the tissue to the organ level. The European dimension of this symposium is extended for researchers, students and exhibitors from Asia and America. During the 3-day symposium the cutting edge in ultrasonic assessment will be presented in oral and poster sessions. The meeting addresses the latest advances in basic science (ultrasound propagation models, non linear acoustics, backscattering, numerical simulations, guided waves), instrumentation and signal analysis (acoustic microscopy, transverse and axial transmission, imaging techniques) and applications (small animals, ultrasonic stimulation, osteoporosis and other diseases).

Committee

Local Committee Guillermo Rus (Local Organizer) Juan Melchor (Organizing committee) Nicolas Bochud (Organizing committee) Laura Peralta (Organizing committee) Antonio Gómez (Organizing committee) Juan Chiachio (Organizing committee) Manuel Chiachio (Organizing committee) Javier Aldaya (Organizing committee) Jose Manuel López (Organizing committee)

International Scientific Committee Pascal Laugier (France) Claus-C. Glüer (Germany) Reinhard Barkmann (Germany) Kay Raum (Germany) Michal Pakula (Poland) Emmanuel Bossy (France) Keith A. Wear (USA) Jonathan J. Kaufmann (USA) Mami Matsukawa (Japan) Dean Ta (China) Jussi Timonen (Finland) Sulin Cheng (Finland) Jukka Jurvelin (Finland)

3

Programme at a glance

4

Programme in detail

Session I: Bone structure - Wed 8, 9:45

Fabien Mézière, Marie Muller,

Emmanuel Bossy and Arnaud Derode

Velocities, attenuations and insights on propagation

paths for the fast and slow waves in numerical

anisotropic porous media

Satoshi Kawasaki, Kazuki Fujimori,

Takeshi Kawakami, Teruhisa Mihata,

Mami Matsukawa

Ultrasonic wave properties of human bone marrow in

femur or tibia

Susanne Schrof, Admir Masic, Sara

Tiburtius, Alf Gerisch, Peter Varga, Kay

Raum

Assessment of collagen fibril orientation in human

lamellar bone with scanning acoustic microscopy and

polarized Raman microscopy

M. Cieszko, Z. Szczepanski, P.Gadzała,

M. Pakuła

Application of histogram mixture model of

microtomografic images to determinations of porosity

and binarization threshold of bone

Michal Pakula, Petro Moilanen, Jalmari

Pirhonen, Tuomas Turpeinen, Jussi

Timonen, Pascal Laugier

Relationships between ultrasonic parameters and

microstructure of human trabecular bone

Session II: Bone structure & fracture - Wed 8, 11:30

Isao Mano, Mami Matsukawa, Takahiko

Otani, Yutaro Yoneda, Kaoru Horii,

Kinji Etoh, Masayuki Sugimoto,

Hidefumi Yokota, Yoshikazu Murakami,

Clinical usefulness of the fast and slow wave system to

discriminate fractures at the proximal femur

K. Rohde, D. Rohrbach, M.K.H. Malo,

C.-C. Glüer, P. Laugier, Q. Grimal, H.

Isaksson, J. Töyräs, J.S. Jurvelin, G.

Schmitz, K. Raum, R. Barkmann

Influence of cortical porosity and bone shape on

Quantitative Ultrasound transmission measurements: a

2D-simulation study

Hiroko Tsuneda, Masahiro Okino,

Katsunori Mizuno, Takahiko Yanagitani,

Shinji Takayanagi, Mami Matsukawa

Electrical potentials in wet bone induced by ultrasound

irradiation

Vassiliki T. Potsika, Vasilios C.

Protopappas, Maria G. Vavva, Kay

Raum, Daniel Rohrbach, Demosthenes

Polyzos, Dimitrios I. Fotiadis

An iterative effective medium approximation for wave

dispersion and attenuation estimations in the healing of

long bones

Peter Varga, Berry Pöpplau, Markus

Heller, Kay Raum

Mechanical causes and consequences of the osteonal

remodelling in the ovine femur

5

Session III: US propagation - Wed 8, 14:00

Eneh Chibuzor, Karjalainen Janne, Malo

Markus, Töyräs Juha, Jurvelin Jukka

Variation in cortical porosity affects the accuracy of

ultrasound measurement of cortical thickness

Fatma Graja, Aroune Duclos, Claude

Depollier

Biot waves in porous ceramic plates: model of defect in

cancellous bone

Pablo C. Iglesias, Noé Jiménez, Javier

Redondo, Elisa E. Konofagou, Francisco

Camarena

Parametric study of transcranial focused ultrasound

propagation for blood-brain barrier opening

Michal Pakula On the macroscopic modeling of wave propagation in

cancellous bone

Marie-Luise Wille, Christian M. Langton Estimation of solid volume fraction from ultrasound

transit time spectroscopy

Poster & coffee break - Wed 8, 15:15

Kim-Cuong T. Nguyen, Lawrence H. Le,

Tho N.H.T. Tran, Edmond H.M. Lou

Ultrasonic crosstalk removal in a transducer array using

an adaptive noise cancellator in the time intercept-

slowness domain

Tho N.H.T. Tran, Lawrence H. Le,

Mauricio D. Sacchi, Vu-Hieu Nguyen,

Edmond H.M. Lou

Application of τ - p transform to filter and reconstruct

multichannel ultrasonic guided-wavefields

Jalmari Pirhonen, Petro Moilanen,

Vantte Kilappa, Pasi Karppinen, Zuomin

Zhao, Risto Myllylä, Sulin Cheng,

Pascal Laugier, Edward Haeggström,

Jussi Timonen

Sensitivity of photo-acoustically generated axial

transmission ultrasound to material and geometrical

properties of human bone: an in vitro study

L. Peralta, A. Gómez, N. Bochud, J.

Melchor, G. Rus, M. Chiachio, J.

Chiachio, G. Ruiz-Cabello, C. Reyes, M.

V. Olmedo

Evolution of implant osteointegration by nonlinear

ultrasound

Pierre Nauleau, Mathieu Chekroun,

Quentin Grimal, Jean-Gabriel Minonzio,

Claire Prada, Pascal Laugier

A step toward the measurement of circumferential

guided waves at the femur neck: validation on an

elliptical bone-mimicking phantom

M. Chiachio, J. Chiachio, N. Bochud, L.

Peralta, A. Gómez, J. Melchor, G. Rus

A stochastic model for bone mechanical evolution based

on the inverse problem

J. Schneider, D. Rohrbach, J.G.

Minonzio, M. Talmant, P. Laugier, K.

Raum

Pilot of an axial transmission ultrasound device for in

vivo cortical bone assessment

Kailiang Xu, Chengcheng Liu, Lida

Xiao, Dan Liu, Dean Ta

Ultrasonic guided waves dispersion reversal in the

fractured long cortical bone: a simulation study

6

B. Fain, J.G. Minonzio, M. Talmant, D.

Cassereau, E. Bossy, P. Laugier

Tridimensionnal finite difference time domain (FDTD)

simulations of guided wave propagation for

improvement of in vivo axial transmission measurements

Session IV: US characterization - Wed 8, 16:00

Fuminori Fujita, Katsunori Mizuno, Isao

Mano, Mami Matsukawa

Observation of fast wave in the initial state of wave

propagation in cancellous bone

E. Grande García, M. Schweikle, P.

Föhr, F. Stark, C. Grosse, R. Burgkart

Three dimensional characterisation of compressional

wave velocities in bovine and porcine femoral bone

G. Rus, N. Bochud, L. Peralta, A.

Gómez, J. Melchor, D. Castello, M.

Chiachio, J.Chiachio

Real-time probabilistic model-based monitoring

biorreactor for engineered bone

J. Karjalainen, M. Pakula, Q. Grimal, J.

Töyräs, J.S. Jurvelin, P. Laugier

Application of Dual Frequency Ultrasound Method in

Through Transmission Measurements

A. Slawig, D. Rohrbach, J.P.

Karjalainen, M.K.H. Malo, J. Töyräs,

J.S. Jurvelin, K. Raum

Acoustic backscatter measurements and simulations of

human femur cortical bone

Simon Bernard, Quentin Grimal, Pascal

Laugier

Recent progresses in the use of resonant ultrasound

spectroscopy for the characterization of the anisotropic

elasticity of mineralized tissues

Session V: Clinical QUS - Thu 9, 9:30

Julie P. Griffin, Paul M. Medin, Edmond

Richer

Dose-Related Long Term Effects of Cervical Spine SRS

on Ultrasound Propagation Velocity - Early Results on a

Porcine Model

Karjalainen Janne, Riekkinen Ossi,

Töyräs Juha, Kröger Heikki, Jurvelin

Jukka

Diagnostic use of ultrasound measurement of apparent

corcital thickness - Age dependence of apparent cortical

thickness

Liukkonen Jukka, Lehenkari Petri,

Hirvasniemi Jukka, Joukainen Antti,

Virén Tuomas, Saarakkala Simo,

Jurvelin Jukka S., Töyräs Juha

Ultrasound Arthroscopy of Human Knee Joint:

Feasibility In Vivo

Christiano B. Machado, Daniel

Rohrbach, Wagner C.A. Pereira, Pascal

Laugier, Kay Raum

On the role of quantitative ultrasound (QUS) in fracture

healing monitoring: what is next?

M.K.H. Malo, O. Riekkinen, M.

Turunen, H. Isaksson, J.P. Karjalainen,

J. Töyräs, J.S. Jurvelin

In situ ultrasound backscatter measurements at

trochanter major

7

Session VI: Guided waves I - Thu 9, 11:30

Lawrence H. Le, Tho N.H.T. Tran,

Mauricio D. Sacchi

Radon or τ - p Transform: a New Tool to Image

Dispersive Guided-Wave Energies in Long Bones

Didier Cassereau, Pierre Nauleau, Aniss

Bendjoudi, Emmanuel Bossy, Jean-

Gabriel Minonzio, Pascal Laugier,

Quentin Grimal

Long distance simulations of ultrasonic inspection of

bone: a finite difference elastodynamic and semi-

analytic diffraction code coupling approach

Josquin Foiret, Jean-Gabriel Minonzio,

Pascal Laugier, Maryline Talmant

A novel procedure using multi-modal axial transmission

for the characterization of elastic and geometrical

properties of cortical bone

Vantte Kilappa, Petro Moilanen, Ari

Salmi, Zuomin Zhao, Risto Myllylä,

Edward Haeggström, Jussi Timonen

Phase-delayed excitation of fundamental flexural guided

wave: numerical simulations in fluid-coated plates

Jean-Gabriel Minonzio, Josquin Foiret,

Petro Moilanen, Jalmari Pirhonen,

Zuomin Zhao, Maryline Talmant, Jussi

Timonen, Pascal Laugier

Axial transmission guided wave measurements on

tubular bone-mimicking phantoms

Session VII: Guided waves II - Thu 9, 14:00

Ludovic Moreau, Jean-Gabriel

Minonzio, Josquin Foiret, Emmanuel

Bossy, Maryline Talmant, P. Laugier

Axial transmission measurement of guided modes on

phantoms with variations of both cortical and soft tissue

thicknesses

Kim-Cuong T. Nguyen, Lawrence H. Le,

Edmond H.M. Lou

Excitation of guided waves in long bones by beam

steering

Tho N.H.T. Tran, Lawrence H. Le,

Mauricio D. Sacchi, Rui Zheng

Multichannel τ - p analysis of ultrasonic guided-

wavefields in long bones: an in-vivo study

Petro Moilanen, Ari Salmi, Pasi

Karppinen, Vantte Kilappa, Zuomin

Zhao, Risto Myllylä, Edward

Haeggström, Jussi Timonen

Photo-acoustic phase-delayed excitation of guided

waves in coated bone phantoms

Session VIII: Non linear US - Thu 9, 15:30

Zhenggang Zhang, Mingxi Deng, Dean

Ta

Experimental observation of second-harmonic

generation of ultrasonic guided waves propagating in

long bones

J. Melchor, W.J. Parnell, G. Rus, N.

Bochud, L. Peralta, A. Gómez, M.

Chiachio, J.Chiachio

Relationship between acoustic and homogeneized

Landau nonlinearity constants in anisotropic bone

N. Bochud, M. Membrilla, L. Peralta, A.

Gómez, J. Melchor, G. Rus, M.

Chiachio, J. Chiachio

Nonlinear harmonic imaging for cortical bone damage

assessment

8

Session IX: Novel instrumentation - Thu 9, 16:30

Christian Baker, Srinath Rajagopal,

Bajram Zeqiri

Phase-Insensitive Sensors for Quantitative Ultrasound

M. Daugschies, K. Rohde, C.-C. Glüer,

R. Barkmann

Feasibility Tests for a new 1 MHz Ultrasound Probe

measuring acoustic anisotropy in cortical bone

Jonathan J. Kaufman, Gangming Luo,

Robert S. Siffert

Ultrasonic Bone Density Assessment of the Radius

Yoshiki Nagatani, Ryosuke O. Tachibana Quantitative analysis of the fast wave frequency

-Investigation using Multichannel Instantaneous

Frequency-

9

List of abstracts

Authors Title Session Schedule

Christian Baker, Srinath Rajagopal,

Bajram Zeqiri

Phase-Insensitive Sensors for Quantitative

Ultrasound

S9 Thu 16:30

Simon Bernard, Quentin Grimal,

Pascal Laugier

Recent progresses in the use of resonant

ultrasound spectroscopy for the

characterization of the anisotropic elasticity

of mineralized tissues

S4 Wed 16:00

N. Bochud, M. Membrilla, L.

Peralta, A. Gómez, J. Melchor, G.

Rus, M. Chiachio, J. Chiachio

Nonlinear harmonic imaging for cortical

bone damage assessment

S8 Thu 15:30

Didier Cassereau, Pierre Nauleau,

Aniss Bendjoudi, Emmanuel Bossy,

Jean-Gabriel Minonzio, Pascal

Laugier, Quentin Grimal

Long distance simulations of ultrasonic

inspection of bone: a finite difference

elastodynamic and semi-analytic diffraction

code coupling approach

S6 Thu 11:30

Eneh Chibuzor, Karjalainen Janne,

Malo Markus, Töyräs Juha, Jurvelin

Jukka

Variation in cortical porosity affects the

accuracy of ultrasound measurement of

cortical thickness

S3 Wed 14:00

M. Cieszko, Z. Szczepanski, P.

Gadzala, M. Pakula

Application of histogram mixture model of

microtomografic images to determinations

of porosity and binarization threshold of

bone

S1 Wed 9:45

M. Daugschies, K. Rohde, C.-C.

Glüer, R. Barkmann

Feasibility Tests for a new 1 MHz

Ultrasound Probe measuring acoustic

anisotropy in cortical bone

S9 Thu 16:30

Josquin Foiret, Jean-Gabriel

Minonzio, Pascal Laugier, Maryline

Talmant

A novel procedure using multi-modal axial

transmission for the characterization of

elastic and geometrical properties of cortical

bone

S6 Thu 11:30

Fuminori Fujita, Katsunori Mizuno,

Isao Mano, Mami Matsukawa

Observation of fast wave in the initial state

of wave propagation in cancellous bone

S4 Wed 16:00

Fatma Graja, Aroune Duclos,

Claude Depollier

Biot waves in porous ceramic plates: model

of defect in cancellous bone

S3 Wed 14:00

E. Grande García, M. Schweikle, P.

Föhr, F. Stark, C. Grosse, R.

Burgkart

Three dimensional characterisation of

compressional wave velocities in bovine and

porcine femoral bone

S4 Wed 16:00

Julie P. Griffin, Paul M. Medin,

Edmond Richer

Dose-Related Long Term Effects of

Cervical Spine SRS on Ultrasound

Propagation Velocity - Early Results on a

Porcine Model

S5 Thu 9:30

10

Pablo C. Iglesias, Noé Jiménez,

Javier Redondo, Elisa E.

Konofagou, Francisco Camarena

Parametric study of transcranial focused

ultrasound propagation for blood-brain

barrier opening

S3 Wed 14:00

Liukkonen Jukka, Lehenkari Petri,

Hirvasniemi Jukka, Joukainen Antti,

Virén Tuomas, Saarakkala Simo,

Jurvelin Jukka S., Töyräs Juha

Ultrasound Arthroscopy of Human Knee

Joint: Feasibility In Vivo

S5 Thu 9:30

Karjalainen Janne, Riekkinen Ossi,

Töyräs Juha, Kröger Heikki,

Jurvelin Jukka

Diagnostic use of ultrasound measurement

of apparent corcital thickness - Age

dependence of apparent cortical thickness

S5 Thu 9:30

J. Karjalainen, M. Pakula, Q.

Grimal, J. Töyräs, J.S. Jurvelin, P.

Laugier

Application of Dual Frequency Ultrasound

Method in Through Transmission

Measurements

S4 Wed 16:00

Jonathan J. Kaufman, Gangming

Luo, Robert S. Siffert

Ultrasonic Bone Density Assessment of the

Radius

S9 Thu 16:30

Satoshi Kawasaki, Kazuki Fujimori,

Takeshi Kawakami, Teruhisa

Mihata, Mami Matsukawa

Ultrasonic wave properties of human bone

marrow in femur or tibia

S1 Wed 9:45

Vantte Kilappa, Petro Moilanen, Ari

Salmi, Zuomin Zhao, Risto Myllylä,

Edward Haeggström, Jussi Timonen

Phase-delayed excitation of fundamental

flexural guided wave: numerical simulations

in fluid-coated plates

S6 Thu 11:30

Lawrence H. Le, Tho N.H.T. Tran,

Mauricio D. Sacchi

Radon or τ - p Transform: a New Tool to

Image Dispersive Guided-Wave Energies in

Long Bones

S6 Thu 11:30

Christiano B. Machado, Daniel

Rohrbach, Wagner C.A. Pereira,

Pascal Laugier, Kay Raum

On the role of quantitative ultrasound

(QUS) in fracture healing monitoring: what

is next?

S5 Thu 9:30

M.K.H. Malo, O. Riekkinen, M.

Turunen, H. Isaksson, J.P.

Karjalainen, J. Töyräs, J.S. Jurvelin

In situ ultrasound backscatter measurements

at trochanter major

S5 Thu 9:30

Isao Mano, Mami Matsukawa,

Takahiko Otani, Yutaro Yoneda,

Kaoru Horii, Kinji Etoh, Masayuki

Sugimoto, Hidefumi Yokota,

Yoshikazu Murakami, Yoshihiko

Kotoura

Clinical usefulness of the fast and slow

wave system to discriminate fractures at the

proximal femur

S2 Wed 11:30

J. Melchor, W.J. Parnell, G. Rus, N.

Bochud, L. Peralta, A. Gómez, M.

Chiachio, J.Chiachio

Relationship between acoustic and

homogeneized Landau nonlinearity

constants in anisotropic bone

S8 Thu 15:30

11

Fabien Mézière, Marie Muller,

Emmanuel Bossy, Arnaud Derode

Velocities, attenuations and insights on

propagation paths for the fast and slow

waves in numerical anisotropic porous media

S1 Wed 9:45

Jean-Gabriel Minonzio, Josquin

Foiret, Petro Moilanen, Jalmari

Pirhonen, Zuomin Zhao, Maryline

Talmant, Jussi Timonen, Pascal

Laugier

Axial transmission guided wave

measurements on tubular bone-mimicking

phantoms

S6 Thu 11:30

Petro Moilanen, Ari Salmi, Pasi

Karppinen, Vantte Kilappa, Zuomin

Zhao, Risto Myllylä, Edward

Haeggström, Jussi Timonen

Photo-acoustic phase-delayed excitation of

guided waves in coated bone phantoms

S7 Thu 14:00

Ludovic Moreau, Jean-Gabriel

Minonzio, Josquin Foiret,

Emmanuel Bossy, Maryline

Talmant, P. Laugier

Axial transmission measurement of guided

modes on phantoms with variations of both

cortical and soft tissue thicknesses

S7 Thu 14:00

Yoshiki Nagatani, Ryosuke O.

Tachibana

Quantitative analysis of the fast wave

frequency -Investigation using Multichannel

Instantaneous Frequency-

S9 Thu 16:30

Kim-Cuong T. Nguyen, Lawrence

H. Le, Edmond H.M. Lou

Excitation of guided waves in long bones by

beam steering

S7 Thu 14:00

Michal Pakula On the macroscopic modeling of wave

propagation in cancellous bone

S3 Wed 14:00

Michal Pakula, Petro Moilanen,

Jalmari Pirhonen, Tuomas

Turpeinen, Jussi Timonen, Pascal

Laugier

Relationships between ultrasonic parameters

and microstructure of human trabecular bone

S1 Wed 9:45

Vassiliki T. Potsika, Vasilios C.

Protopappas, Maria G. Vavva, Kay

Raum, Daniel Rohrbach,

Demosthenes Polyzos, Dimitrios I.

Fotiadis

An iterative effective medium

approximation for wave dispersion and

attenuation estimations in the healing of

long bones

S2 Wed 11:30

K. Rohde, D. Rohrbach, M.K.H.

Malo, C.-C. Glüer, P. Laugier, Q.

Grimal, H. Isaksson, J. Töyräs, J.S.

Jurvelin, G. Schmitz, K. Raum, R.

Barkmann

Influence of cortical porosity and bone

shape on Quantitative Ultrasound

transmission measurements: a 2D-simulation

study

S2 Wed 11:30

G. Rus, N. Bochud, L. Peralta, A.

Gómez, J. Melchor, D. Castello, M.

Chiachio, J.Chiachio

Real-time probabilistic model-based

monitoring biorreactor for engineered bone

S4 Wed 16:00

Susanne Schrof, Admir Masic, Sara

Tiburtius, Alf Gerisch, Peter Varga,

Kay Raum

Assessment of collagen fibril orientation in

human lamellar bone with scanning acoustic

microscopy and polarized Raman

microscopy

S1 Wed 9:45

12

A. Slawig, D. Rohrbach, J.P.

Karjalainen, M.K.H. Malo, J.

Töyräs, J.S. Jurvelin, K. Raum

Acoustic backscatter measurements and

simulations of human femur cortical bone

S4 Wed 16:00

Tho N.H.T. Tran, Lawrence H. Le,

Mauricio D. Sacchi, Rui Zheng

Multichannel τ - p analysis of ultrasonic

guided-wavefields in long bones: an in-vivo

study

S7 Thu 14:00

Hiroko Tsuneda, Masahiro Okino,

Katsunori Mizuno, Takahiko

Yanagitani, Shinji Takayanagi,

Mami Matsukawa

Electrical potentials in wet bone induced by

ultrasound irradiation

S2 Wed 11:30

Peter Varga, Berry Pöpplau, Markus

Heller, Kay Raum

Mechanical causes and consequences of the

osteonal remodelling in the ovine femur

S2 Wed 11:30

Marie-Luise Wille, Christian M.

Langton

Estimation of solid volume fraction from

ultrasound transit time spectroscopy

S3 Wed 14:00

Zhenggang Zhang, Mingxi Deng,

Dean Ta

Experimental observation of second-

harmonic generation of ultrasonic guided

waves propagating in long bones

S8 Thu 15:30

M. Chiachio, J. Chiachio, N.

Bochud, L. Peralta, A. Gómez, J.

Melchor, G. Rus

A stochastic model for bone mechanical

evolution based on the inverse problem

B. Fain, J.G. Minonzio, M. Talmant,

D. Cassereau, E. Bossy, P. Laugier

Tridimensionnal finite difference time

domain (FDTD) simulations of guided wave

propagation for improvement of in vivo

axial transmission measurements

Pierre Nauleau, Mathieu Chekroun,

Quentin Grimal, Jean-Gabriel

Minonzio, Claire Prada, Pascal

Laugier

A step toward the measurement of

circumferential guided waves at the femur

neck: validation on an elliptical bone-

mimicking phantom

Kim-Cuong T. Nguyen, Lawrence

H. Le, Tho N.H.T. Tran, Edmond

H.M. Lou

Ultrasonic crosstalk removal in a transducer

array using an adaptive noise cancellator in

the time intercept-slowness domain

L. Peralta, A. Gómez, N. Bochud, J.

Melchor, G. Rus, M. Chiachio, J.

Chiachio, G. Ruiz-Cabello, C.

Reyes, M. V. Olmedo

Evolution of implant osteointegration by

nonlinear ultrasound

Jalmari Pirhonen, Petro Moilanen,

Vantte Kilappa, Pasi Karppinen,

Zuomin Zhao, Risto Myllylä, Sulin

Cheng, Pascal Laugier, Edward

Haeggström, Jussi Timonen

Sensitivity of photo-acoustically generated

axial transmission ultrasound to material

and geometrical properties of human bone:

an in vitro study

J. Schneider, D. Rohrbach, J.G.

Minonzio, M. Talmant, P. Laugier,

K. Raum

Pilot of an axial transmission ultrasound

device for in vivo cortical bone assessment

13

Tho N.H.T. Tran, Lawrence H. Le,

Mauricio D. Sacchi, Vu-Hieu

Nguyen, Edmond H.M. Lou

Application of τ - p transform to filter and

reconstruct multichannel ultrasonic guided-

wavefields

Kailiang Xu, Chengcheng Liu, Lida

Xiao, Dan Liu, Dean Ta

Ultrasonic guided waves dispersion reversal

in the fractured long cortical bone: a

simulation study

14

Venue The ESUCB 2013 will be held at the "Facultad de Medicina" building, University of Granada, 10 minutes walking from the city centre.

The conference sessions will be held at the "Salon de Actos", the reception at the entrance of the "Salon de Actos" and the coffee and posters at the corridor right outside that entrance, as shown in the map below:

15

Wifi access Wireless connection is available during the conference at the Venue and all over the University of Granada. To connect, choose the network "cviugr" and insert the following data when prompted: USER: esucb@invitados.ugr.es PASSWORD: BONE2013++ In addition, the "eduroam" service is available inside University of Granada, so if your original institution is adhered to this project and your laptop is configured accordingly, you should automatically connect to this network.

University The University of Granada, founded in 1531, continues a long teaching tradition, the roots of which can be traced back to the madrasahs of the last Nasrid Kingdom. The University is a vibrant presence in the city of Granada, benefiting from the distinctive beauty of its environment and a privileged geographical location due to its proximity to the Sierra Nevada, an excellent ski resort and the Mediterranean coast, with several major tourist sites, including Motril, Almuñécar and Salobreña. In Granada, there are four University Campuses, as well as the “Campus Centro”, in which all the centres spread throughout the historic part of the city are brought together. The UGR's policy of using buildings of historical and cultural value has enriched its heritage, as well as promoting the restoration and maintenance of these buildings. In addition to this emphasis on more traditional elements, the Health Science Technological Park, which is still being developed, demonstrates our strong commitment to innovation by promoting interaction with technological bio-health companies and favouring high-quality healthcare and biomedical knowledge.

Granada The city has been inhabited from the dawn of history. Phoenicians, Carthagenians, Greeks and Roman have lived in this city. In the 8th century, nearly all the Iberian Peninsula was conquered (711-718) by Muslim armies from North Africa. Córdoba, the capital of the caliphate, was the largest, richest and most sophisticated city of medieval Western Europe. However, by the 11th century, the Muslim territories had fractured into rival Taifa kingdoms. With the arrival of the Zirid dynasty in 1013, Granada became an independent emirate Taifa of Granada and then the Kingdom of Granada in 1238. Important monuments from that period have survived until the present time: the Alhambra, the Generalife, the Albayzin, Arab baths.

16

On January 2, 1492, the last Muslim leader, Muhammad XII known as Boabdil to the Spanish, surrendered complete control of Granada to Ferdinand and Isabella, "The Catholic Monarchs", after the city had been besieged. It is one of the most significant events in Granada's history. At the same time Christopher Columbus came to Granada to ask Kings Isabel and Ferdinand for funding to build ships that led to the conquer of the Americas. Subsequent colonization led to the creation of the Spanish Empire, the largest empire in the world for its time. Over the course of the sixteenth century, Granada took on an ever more Christian and Castilian character, as immigrants flocked to the city from other parts of the Iberian Peninsula. Granada is currently inhabited by 300,000 people, who not only enjoys a wealth of heritage and history but a living reality and present with a multitude of cultural and social activities. The University was founded in the early sixteenth century, and the students create a lively, youthful atmosphere. Granada is a multicultural meeting place, a space open to welcoming visitors from all corners of the world.

Architecture There are many important Moorish and Catholic architectural sites in Granada: The Alhambra and Generalife, the Palace of Charles V, Granada Cathedral and Royal Chapel wtih the tombs of Isabella and Ferdinand, the Catholic Monarchs. The Albayzin is the ancient Arab quarter, containing many original houses from the 16th century.

Region The city of Granada in Andalusia in the South of Spain at the foot of the Sierra Nevada mountains and national park, at an elevation of 700 metres above sea level. Yet it is only one hour from the Mediterrean coast, the Costa Tropical so that it is possible to go skiing and sunbathe on the beach on the same day.

Climate Spring is one of the best times to visit Granada. The average temperature ranges between 15ºC and 30ºC. The climate is sunny and dry, with an average of 4 or 5 days per month of rainfall. Granada Tourism: www.turgranada.es Alhambra: www.alhambra-patronato.es

17

Getting to Granada

By plane: Airport information Granada is situated in the southernmost region of Spain, Andalusia. It has a modern network of roads and motorways, allowing for easy access. The national airport, Aeropuerto de Granada - Jaén Federico García Lorca is 14 Km from the centre of the town, where the venue of the meeting is located. If you arrive at the Granada airport, the most convenient way to reach to Granada city centre is probably to get a taxi at the airport main entrance. The taxi costs about 28 € from the airport to the city centre. There is also a confortable and frequent airport bus shuttle that takes you to the centre of Granada in about 20-25 min. The ticket costs 3 €. Airports with direct flight to Granada Spain:

Barcelona Madrid Melilla Palma de Mallorca

UK: Liverpool London Stansted Nottingham East Midlands

Germany: Frankfurt, Hahn

Italy: Bologna Milano, Bergamo

By train The train station is located right in the city center. Address: Avda. Andaluces s/n 18014 Granada National Information and reservation: +34 902 24 02 02. International information: +34 902 24 34 02 Train Information: www.renfe.es

By car A-92, is connected to Seville in 2.5 hours time and to Malaga in 1, 2 hours time via the A-92 motorway, making Granada an excellent start point for a visit to Andalusia. The motorway A-44 is connected Motril, Tropical Coast, in only 45 minutes.

18

By bus Malaga airport is 125km from Granada and has numerous national and international flight connections. You can get a bus from Malaga airport directly to Granada bus station. It leaves everyday at 11:30 and at 18:30. It takes two and a half hours (it has several stops). The price is 10 €. To buy tickets online visit www.alsa.es.

By taxi Another good option to get to Granada is clubbing together with 2 or 3 people and get a taxi. A taxi from Malaga is 150 € during the weekdays and 174 € during the weekends, and the trip takes one and a half hours.

19

Worldwide participation

Sponsors

Contact

Local organiser: Dr. Guillermo Rus grus@ugr.es Tel: +34 958249482, Fax: +34 958249959 Dpt. Structural Mechanics University of Granada ETSICCP, Campus de Fuentenueva 18071 Granada, Spain www.ugr.es/~grus

Technical secretariat: Inmaculada Ortiz Viajes el corte ingl s .A. ivisi n Congresos congresosgranada@viajeseci.es Luis Amador 26 Centro de Negocios Cámara Granada 18014 Granada, Spain Tel.- 958 53 68 20 - 958 53 68 21 Fax.- 958 25 48 92