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ESO-ESMO 2nd InternationalConsensus Guidelines for
Advanced Breast Cancer (ABC 2)
By
Indra Wiradinata
Advisor
D! Dr! Wirs"a Arif #$ S%B(&)On'
ISBO$ *O+,GA(OEMBE .-/$ 201)
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Introduction
ABC
treata3le 3ut incura3le Goal o%ti"i4e en5t6 7 8uality
of life
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Met6odolo5y
+6ree "ain issues at ABC 2 Ino%era3le ocally Advanced Breast
Cancer (ABC) 3ot6 in9a""atory and
on in9a""atory Metastatic Breast Cancer (MBC)
S%eci:c de:nition t6at ;as dee"edi"%ortant
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General Guidelines
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General Guidelines
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General Guidelines
A5e "ay in9uence 3reast cancertreat"ent$ 3ut it s6ould not 3e
5uidin5
force
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Ino%era3l
e on-In9a""atory ABC
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Ino%era3le on-
In9a""atoryABC
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Ino%era3leon-In9a""ato
ry ABC
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Ino%era3leon-
In9a""atoryABC
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Ino%era3le
In9a""atory ABC
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In9a""atory Breast Cancer(IBC)
,sually youn5er a5e at dia5nosis
#i56er tu"our 5rade
E ne5ative
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S%eci:c ABC *o%ulations
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S%eci:c ABC *o%ulations
Male %atient ;it6 ABC ABC 1reco""endations still valid for ABC
2
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S%eci:cSites of
Metastases
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S%eci:c Sites of Metastases
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S%eci:c Sites of Metastases
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S%eci:cSites of
Metastases
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,%dateon E%ositive
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,%dateon #er-
2*ositiv
e ABC
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,%date on#er-2*ositi
ve
ABC
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,%date on
#er-2*ositiv
e ABC
, d t # 2 ti
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,%date on #er-2 e5ativeABC
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,%date on Sur5ery of +6e *ri"ary+u"our in Sta5e I at
Dia5nosis
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Conclusions MBC incura3le disease
ABC %oor %ro5nosis 6i56 ris' ofdistant reccurence
ABC 8uestions still unans;ered Mana5e"ent strate5ies
O%ti"al dru5 use
Individuali4ed treat"ent
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+6an' =ou !!!!!!
