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Epidemioloy and control
strategy of rabies
OIE: Regional Training on Rabies
Tokyo/Yokohama, Japan 5-8 August 2014
Satoshi INOUE, PhD DVM
Laboratory of Transmission Control of Zoonosis,
Department of Veterinary Science,
National Institute of Infectious Diseases, Japan
Key words of Rabies control
Diagnosis
Mangment of patients before and after death
Vaccine and Imunoglobulin for humans
Potency requirements
Dog rabies control
Prevention and control of rabies in wild animals
Surveillance
Rabies-free areas
WHO Expert Consultation on Rabies WHO-TRS 982
2
Reservoirs of animal rabies
Asia: Dog etc.
Africa: Dog, Jackal, etc.
E.Europe: Fox, Raccoon dog, etc.
N.America: Raccoon, Skunk, Fox, Bat, etc.
Latin America: Mangoose, Bat, etc.
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H. Bourhy - Rabies - Tokyo, Japan - 5/02/2013
The risk is linked to the age
Children are more often
bitten than adults …
Children are bitten
at the head and the
neck
>40% of those seeking
PEP and those dying
of rabies are children
less than 15 yrs old
More than 99% of the human
cases are due to
canine rabies
Stray dogs
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Key words of Rabies control
Dog rabies control
- Canine mass parenteral vaccination campaigns
- Management of vaccination campaigns
- Study of dog ecology
- Vaccination and immunization coverage
- Implementing and monitoring dog vaccintion campaigns
- Cost-effectiveness of dog vaccination
- Human dog population management
- Animal birth control (ABC)
WHO Expert Consultation on Rabies WHO-TRS 982
Evidence based measures
has been done correctly?
5
Key words of Rabies control
Dog rabies control
- Canine mass parenteral vaccination campaigns
- Management of vaccination campaigns
- Study of dog ecology
WHO Expert Consultation on Rabies WHO-TRS 982
Workshop on Strengthening Cooperation and Sharing Information on Rabies among ASEAN Plus Three Countries
Dr Ronello Abila
Regional Coordinator,
OIE South East AsiaAnimal Rabies
Country 2001 2002 2003 2004 2005 2006
Brunei
Cambodia ()+ ()+ ()+ ()+ ()+ NR
Indonesia 65 257 172 578 399 36
Laos 65 55 37 ()+ ()+ NR
Malaysia No rabies since 1999
Myanmar 3 2 1 4 7 0
Philippines ()+ 981 1475 964 197 568
Singapore No rabies since 1953
Thailand 220 531 185 252 163 166
Vietnam 14 18 5 5 15 9
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Philippines 300,000 doses (in February 2014)
Afghanistan 200,000 (in January 2014)
Vietnam 500,000 (in December 2013)
Nepal 200,000 (in October 2013)
Butan 20,000 (in September 2013) Myanmar 200,000 (in September 2013)
Bangladesh 200,000 (in July 2013)
Indonesia 200,000 (in July 2013)
Sri Lanka 300,400 (in June 2013)
Key words of Rabies control
Dog rabies control
- Canine mass parenteral vaccination campaigns
- Management
- Vaccination and immunization coverage
- Implementing and monitoring dog vaccintion campaigns
- Cost-effectiveness of dog vaccination
- Human dog population management
- Animal birth control (ABC)
WHO Expert Consultation on Rabies WHO-TRS 982
7
Features of dog
in Asia
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3288
1942
7037
159
0
2000
4000
6000
8000
50 53 56 59 62 65 68 71 74 77 80 83 86 89 92 95 98 01 04 07
病例数
9
Key words of Rabies control
Dog rabies control
- Canine mass parenteral vaccination campaigns vaccination campaigns
- Study of dog ecologyctiveness of dog n
- Human dog population management
- Animal birth control (ABC)
- Animal birth contorol (ABC)
WHO Expert Consultation on Rabies WHO-TRS 982
Quang Minh Nhat Thanhnien 18/06/2014 09:35U
Viet-jo.com
In 2014, January to June
Bite incidences = 160,000
Rabies patients = 28
National government required
Vaccination of owned dogs
Prohibition of dog run loose
Leash a dog in public area
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Key words of Rabies control
Dog rabies control
- Canine mass parenteral vaccination campaigns
Save human life
by the management
of owned dogs
WHO Expert Consultation on Rabies WHO-TRS 982
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Features of rabies
circulation in
animals
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Hanlon et al, In Rabies (2nd Ed), 2007 Interspecific Transmission of RABV in the USA
Phylogenetic tree of Philippine RABV glycoprotein
Saito et al. PLoS Negl Trop Dis, 2013
• Samples collected during period of 2004-2013
• All 235 samples are dog derived
• Rabies status confirmed by DFA
• RT-PCR sequencing performed on RABV glycoprotein
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★安徽省 ★浙江省 ★江西省
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17 July - 31 Decmber in 2013
Total Positive
Carnivora 1,019 276
Ferret badger 831 276
Dog 1,553 1
1 January - 26 June in 2014
Total Positive
Carnivora 190 103
Ferret badger 153 103
Dog 496 0
Rabies cases in Taiwan
Key words of Rabies control in laboratory
Diagnosis Laboratory
Mangment of patients before and after death
Vaccine and Imunoglobulin for humans
Potency requirements Laboratory
Dog rabies control
Prevention and control of rabies in wild animals Laboratory
Surveillance Laboratory
Rabies-free areas Laboratory
WHO Expert Consultation on Rabies WHO-TRS 982
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Keep and expand rabies free area
by the evidence of laboratory!
NO MORE RABIES
