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Epidemiology of HIV Among Pediatric* Cases in Florida, through 2012 HIV/AIDS and Hepatitis Section Division of Disease Control and Health Protection Data as of 06/30/2013 *Infected prior to age 13 Created: 05/17/13 Revision: To protect, promote and improve the health of all people in Florida through integrated state, county, and community efforts.

Epidemiology of HIV Among Pediatric* Cases in Florida, through 2012

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Page 1: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Epidemiology of HIV Among Pediatric* Cases

in Florida, through 2012 HIV/AIDS and Hepatitis SectionDivision of Disease Control and Health ProtectionData as of 06/30/2013*Infected prior to age 13

Created: 05/17/13

Revision: 10/09/13

To protect, promote and improve the health of all people in Florida through integrated state, county, and community efforts.

Page 2: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Pediatric HIV Surveillance

Pediatric HIV cases include those persons who were infected with HIV UNDER 13 years of age.

Pediatric AIDS cases include those pediatric HIV cases that have developed AIDS, regardless of age of AIDS diagnosis.

The first pediatric AIDS case was born in 1979, diagnosed in 1982 and reported in 1983.

HIV (not AIDS) reporting began 07/1997.

Page 3: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Pediatric HIV SurveillanceLimitations

Limitations: Due to reporting lags, the most recent

calendar year data are considered to be provisional.

HIV/AIDS Surveillance data are always being updated as newly diagnosed pediatric cases are identified, even if years later.

Page 4: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Acronyms

ART = Antiretroviral TherapyAZT = Antiretroviral Zidovudine TherapyIDU = Injecting Drug UseNIR = No Identified Risk

Page 5: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Pediatric AIDS Cases by Age Group at Diagnosis and Year of

Diagnosis, 1990-2012, Florida

These data represent an 87% decline in pediatric AIDS cases by year of diagnosis from 1992 (N=178) to 2012 (N=24). Due to reporting lags, 2012 data by year of diagnosis are provisional. Data as of 06/30/2013.

0

20

40

60

80

100

120

90 91 92 93 94 95 96 97 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12

Year of Diagnosis

Nu

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ases

Aged < 2 years at AIDS diagnosis

Aged >= 2 years at AIDS diagnosisN=1,526

Page 6: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Pediatric AIDS Cases, by Age Group and

Year of Diagnosis, 1990-2012, Florida

0

10

20

30

40

50

60

70

80

90

90 91 92 93 94 95 96 97 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12

Year of Diagnosis

Nu

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ases

<1 yrs 1-5 yrs 6-12 yrs 13+ yrs

Age Group

Note: As time goes on, the pediatric HIV cases are more likely to NOT develop AIDS until after age 12.

N=1,526

Page 7: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

0

20

40

60

80

100

120

90 91 92 93 94 95 96 97 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12

Year of Diagnosis

Pe

rce

nt

of

Ca

se

s

<1 yrs 1-5 yrs 6-12 yrs 13+ yrs

Age Group

The number of perinatally infected persons aging to adolescence and adulthood before being diagnosed with AIDS is increasing gradually. This may be an indication of successful treatment and care.

Pediatric AIDS Cases, by Age Group and

Year of Diagnosis, 1990-2012, Florida

N=1,526

Page 8: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Cumulative Pediatric AIDS Cases,Reported 1983 through 2012,

by County, Florida

Statewide data:N=1,883Number of Cases

0

1 - 10

11 - 25

26 - 50

over 50

Note: The first pediatric AIDS case was reported in 1983.Data as of 06/30/2013

Page 9: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Cumulative Pediatric HIV (not AIDS) Cases,

Reported 07/1997 through 12/2012, by County, Florida

Statewide data:N=646

Note: HIV (not AIDS) reporting began 07/1997.Data as of 06/30/2013

Number of Cases

0

1 - 10

11 - 20

over 20

Page 10: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Cumulative Pediatric AIDS Cases Reported For Selected States,

Reported through 2011*

Reporting State # of Cases % of TotalNew York 2,457 26%Florida 1,571 17%New Jersey 816 9%California 705 7%Texas 396 4%Pennsylvania 375 4%Maryland 345 4%Illinois 287 3%Georgia 254 3%Massachusetts 234 2%Connecticut 187 2%Virginia 188 2%District of Columbia 193 2%Remaining States 1,513 16%

Total Cases 9,521 100% Source: Cumulative Data from CDC, HIV Surveillance Report, 2011, Vol. 23, Table 20

*Remainder of Area includes the remaining states

Page 11: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

10%

75%

13%

1% White

Black

Hispanic

Other

44%21%

29% 6%

Pediatric HIV Infection Cases N=2,529

Population Estimates

N= 2,851,616

Note: Non-Hispanic blacks are disproportionately affected by HIV disease compared with those of other race/ethnicities. This same trend is seen in adult HIV infection cases but is more pronounced in those diagnosed with HIV Disease under 13 years of age. *The first pediatric AIDS case was reported in 1983.**Source: Population estimates are provided by Florida CHARTS as of 05/03/2013.

Pediatric* HIV Infection Cases and State Population**

in Children <13 years of age, by Race/Ethnicity, Reported* through 2012, Florida

Page 12: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Cumulative Pediatric (<13 yr.) HIV Infection Cases by Mode of Exposure

United States*(AIDS cases reported through 2011)

(N=9,521)

Florida (reported through 2012)

(N=2,529)

Other Pediatric

Risk**9%

Perinatally Acquired

91%

* Source: CDC. (2013). HIV Surveillance Report, 2011. Vol. 23, Table 2a. (2012 data not available.)**Other Pediatric Risk includes receipt of blood products or unknown risk.

Other Pediatric

Risk**5%

Perinatally Acquired

95% N=2,410N=8,658

Page 13: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Cumulative Pediatric HIV Infection Cases, by “Expanded” Modes of Exposure,

Reported through 2012, Florida

22%

11%

2%

34%

25%

1%

1%<1%

2%1%

1%

21%: Mom-Injection Drug User

11%: Mom-Sex w/ Injection Drug User

2%: Mom-sex w/ Male Sex with Male

35%: Mom-sex w/ person w/ HIV/AIDS

1%: Mom-Blood Recipient

<1%: Mom-sex w/ blood recipient

25%: Mom-HIV/AIDS, Risk Unknown

2%: Ped-Hemophilia*

1%: Ped-Transfus/Transplant*

1%: Ped-Confirmed Other*

1%: Ped-No Identified Risk*

*Note: 5% (exploded pieces) are NOT perinatal transmission cases

N=2,410

Page 14: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Prevalence of AIDS-Defining Conditions* Most Commonly Reported Among Pediatric Cases,

Reported through 2012, FloridaAIDS Defining Condition # Cases % Cases

Pneumocystis pneumonia 490 26%

Bacterial infections 432 23%

Candidiasis, esophageal 408 22%

Wasting syndrome 372 20%

Lymphoid interstitial pneumonia 301 16%

HIV encephalopathy 258 14%

Cytomegalovirus disease 145 8%

Herpes simplex 117 6%

Candidiasis, bronchi or lungs 84 4%

Cryptosporidiosis 81 4%

No Disease (Immune suppressed only)** 246 13%

Total Cases 1,883

Note: Of the 2,529 HIV/AIDS pediatric cases, 1,883 (74%) have developed AIDS. *Data are NOT mutually exclusive, many cases have more than one disease.**Immune suppressed: CD4 count <200ul or CD4 percent <14%.

Page 15: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Perinatal Acquired HIV Infected Cases

Page 16: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012
Page 17: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012
Page 18: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012
Page 19: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

0

20

40

60

80

100

120

79 81 83 85 87 89 91 93 95 97 99 01 03 05 07 09 11

Year of Birth

Nu

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ases

Perinatally Acquired HIV Infected Cases,Born in Florida,

by Year of Birth, 1979-2012Birth # % change

2001 382002 21 -45%2003 20 -5%2004 13 -35%2005 14 8%2006 19 36%2007 17 -11%2008 11 -35%2009 9 -18%2010 6 -33%2011 3 -50%2012 7 133%

Note: These data represent a 94% decline in HIV-perinatally infected births from 1993 (N=109) to 2012 (N=7). These data include ALL perinatally acquired HIV Infection cases BORN in Florida.2012 data are provisional. None of the babies born since 2010 have developed AIDS.Data as of 06/30/2013

N=1,197

Page 20: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

0102030405060708090

100

93 94 95 96 97 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12

Year of Report

Nu

mb

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ases

BlackHispanic

White

Note: The majority of the perinatally acquired HIV Infection cases born in Florida are black. They represent greater than 70% of the cases for most years. Data for other/mixed race/ethnicity groups (N=11) for the same time period is not shown.

Perinatally Acquired HIV Infection Cases, Born in Florida, by Race/Ethnicity and

Year of Birth, 1993-2012

N=1,197

Page 21: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

0

10

20

30

40

50

60

70

80

79 81 83 85 87 89 91 93 95 97 99 01 03 05 07 09 11

Year of Birth

Nu

mb

er

of

Ca

se

s

Heterosexual Contact Mother's Risk not Specified Injection drug use Transfusion

Note: Since 1992 a steady decline was observed for all risks, although heterosexual contact remains the primary mode of exposure among mothers infected with HIV.

Perinatally Acquired HIV Infection Cases Born in Florida, by Mother’s Mode of

Exposure and Year of Birth, 1979-2012

N=1,197

Page 22: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

0%

27%

58%

15%

Mother's risknot specified

Heterosexualcontact

Injection druguse

Transfusion

1%15%

67%

17%

Born 1979-1993N =625

Born 1994-2012N =572

Perinatally Acquired HIV Infection CasesBorn in Florida, by Mother’s Mode of Exposure

and Year of Birth, 1979-2012

Note: Among children who were infected perinatally with HIV/AIDS, the distribution of their mothers’ exposure categories has changed over time. For both time periods, heterosexual contact was the highest risk, with 58% of the cases born between 1979-1993, increasing to 67% of cases born between 1994-2012.

N=1,197

Page 23: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

8%

9%

81%

1%White

Black

Hispanic

Other 21%

6%29%

44%

Perinatally Acquired HIV Infection Cases

N=1,197

Population EstimatesN= 2,851,616

Perinatally Acquired HIV Infection CasesBorn in Florida, and State Population*,

by Race/Ethnicity, Born through 2012, Florida

Note: Perinatally acquired HIV infection cases among non-Hispanic blacks are disproportionately affected compared with those of other race/ethnicities. *Source: Population estimates are provided by FloridaCHARTS as of 5/17/2013.

Page 24: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

020406080

100120140160180200

0-5 6-11 12-17

18-23

2 3 4 5 6 7 8 9 10 11 12 13

Nu

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ases

Age in Months Age in YearsOne half (50%, N=188) of the 377 perinatal HIV (not AIDS) cases born through 2012 were diagnosed less than the first 6 months of life. Over two-thirds (67%, N=253) of these perinatal HIV cases were diagnosed under the age of two. Furthermore, less than 1% (N=2) were diagnosed with a perinatal risk after the age of 12.

< 2 yrs of age

Perinatally Acquired HIV Infection Cases Born in Florida, 1979-2012,

by Age at HIV Diagnosis (N=377)

Page 25: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

0

50

100

150

200

250

0-5 6-11

12-17

18-23

2 3 4 5 6 7 8 9 10 11 12 13* 14* 15* 16* 17* 18* 19* 20+

Nu

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ases

Age in Months

Age in Years

< 2 yrs of age

Nearly three-fifths (58%) (N=477) of the perinatal AIDS cases born through 2012 (N=820), were diagnosed with AIDS prior to the age of two. The number of AIDS cases diagnosed after age two decreases by age. * 12% (N=102) of the cumulative AIDS cases were not diagnosed with AIDS until after the age of twelve (which is up from 5% in 2003).

Perinatally Acquired AIDS CasesBorn in Florida, 1979-2012,

by Age at AIDS Diagnosis, (N=820)

Page 26: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

AIDS-Defining Conditions for Perinatally Acquired AIDS Cases

Less than Two Years of Age,Born in Florida 1979-2012,

by Age at AIDS Diagnosis (N=477)

0

10

20

30

40

50

0 2 4 6 8 10 12 14 16 18 20 22

Age in Months

Nu

mb

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f C

ases

Pneumocystis pneumonia

Other AIDS defining

conditions

The peak of PCP in children with perinatally acquired AIDS is four months of age. The age at diagnosis for the other AIDS-defining conditions is much more evenly distributed during the first two years of life.

Page 27: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Note: These data represent a 100% decline in perinatally acquired AIDS cases from 1992 (N=95) to 2012 (N=0).2012 data are provisional. Data as of 06/30/2013.

0

20

40

60

80

90 91 92 93 94 95 96 97 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12

Year of Birth

Nu

mb

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f C

ases

< 2 yrs.

>= 2 yrs.

Age Group

Perinatally Acquired AIDS CasesBorn in Florida 1990-2012,

by Age Group and Year of Birth (N=626)

Page 28: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Living Perinatally Acquired HIV Infection Cases, by County of Birth,

Born in Florida 1979 through 2012

N=819Number of Cases

0

1 - 10

11 - 25

26 - 50

over 50

Florida has 819 living Perinatally Acquired HIV Infection cases born 1979 through 2012, with the majority (57%) of these cases born in South Florida: Miami-Dade (N=233), Broward (N=134) and Palm Beach (N=100). Data as of 06/30/2013

Page 29: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

0

20

40

60

80

100

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32

Current Age

Nu

mb

er

of

Cases

HIV (not AIDS) AIDS

Current Age* Distribution ofLiving Perinatally Acquired HIV Infection Cases

by Disease Status, Born in Florida, 1979 through 2012 (N=819)

*Current age of living (not known dead) HIV/AIDS perinatal cases born through 2012.Data as of 06/30/2013

Page 30: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Region of Birth # of cases % of TotalArea 01* 2 2%Area 03* 1 1%Area 08 (Lee Only) 3 3%Area 08 (not Lee)* 0 0%Area 15* 5 6%Broward County 17 20%Duval County 9 10%Hillsborough/Pinellas Counties 5 6%Miami-Dade County 18 21%Orange County 11 13%Palm Beach County 7 8%Polk 2 2%Remainder of state 6 7%TOTAL CASES 86 100%*Area 1 = Escambia, Okaloosa, Santa Rosa & Walton Counties;

*Area 3 = Alachua, Bradford, Columbia, Dixie, Gilchrist, Hamilton, Lafayette, Levy, Putnam, Suw annee, & Union Counties;

* Area 8 (not Lee) = Charlotte, Collier, DeSoto, Glades, Hendry & Sarasota Counties.

*Area 15 = St. Lucie, Indian River, Martin, and Okeechobee Counties.

Born 2005-2012

*A total of 5 perinatal cases reported in Florida were born outside of the US and NOT included in these data.

Perinatally Acquired HIV Infection Cases,by Selected Regions of Birth

Born in Florida 2005 through 2012

Page 31: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

75%

8%9%

8% 0-5 months

6-12 months

1 year

2+ years

62%

12%

13% 13%

HIV (not AIDS) Cases (N=78) AIDS Cases (N=8)

Perinatally Acquired HIV Infection CasesBorn in Florida, 2005-2012,

by Disease Status and Age Group (N=86)

Note: Between 2005 and 2012 there were a total of 86 perinatally acquired HIV infection cases born in Florida. Of those cases 83% (n=65) were diagnosed with HIV within the first year of life. Likewise, 9% (n=8) of the perinatally infected cases born in Florida have been diagnosed and reported with AIDS. Among the eight perinatal AIDS cases, 75% (n=6) developed AIDS within the first year of life.

Page 32: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Time of Maternal HIV TestingAmong Perinatally Acquired HIV Infection Cases Born in Florida, 2005-2012 (N=86)

Note: One half (50%, n=42) of the 86 HIV-infected mothers who gave birth in Florida between 2005 and 2012 knew they were infected before delivery. It is important for HIV-infected pregnant women to know their HIV infection status in order to make informed decisions about antiretroviral therapy to reduce perinatal transmission of HIV to their infants. The Public Health Service recommends that all pregnant women be offered HIV counseling and voluntary HIV tests.

50%

17%

10%

22%

1%Before Pregnancy (n=42)

During Pregnancy (n=15)

At Delivery (n=9)

After Birth (n=19)

Unknown (n=1)

Page 33: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Women Giving Birth to Perinatally Acquired HIV Positive Babies in

Florida by Mother’s Knowledge of HIV Status at Delivery by Year of Birth, 2005-2012

0%

20%

40%

60%

80%

100%Before Delivery After Delivery

Note: The proportion of pregnant women giving birth to a child diagnosed with HIV and who knew their HIV status prior to delivery varies from year to year, ranging from 50% to 90% or higher.

Page 34: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Possible Missed Opportunities that Could Have Prevented Perinatal Transmission of HIV

Among HIV Positive Babies Born in Florida, 2005-2012

Total Born Florida, 2005 - 2012 86

Missed Opportunities Number PercentMom's HIV Status NOT Known Before Birth 19 22%Inadequate Prenatal Care* 60 70%No Prenatal Antiretroviral Therapy 50 58%No Antiretroviral Therapy at Delivery 37 43%Non-Caesarean Birth 34 40%No Neonatal Antiretroviral Therapy 19 22%Breast Fed 7 8%Other Contributing Factors** Number PercentMom was a substance abuser during pregnancy 26 30%Mom acquired an STD during pregnancy 30 35%*Inadequate prenatal care indicates prenatal care after the 4th month and less than 5 visits

**The same child can be in multiple categories

Page 35: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Perinatally Acquired HIV Infection Cases in Children Whose Mom’s HIV status was Known

Prior to Delivery Born in Florida, 2005-2012,by Receipt of Adequate Prenatal Care and

Any Prenatal Antiretroviral Therapy (ART) (N=57)

Adequate Prenatal CareBegan by 4th month with 5+ visits

Any Prenatal ARTAZT and/or antiretrovirals

Yes No

32%

68%

61%

39%

Page 36: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Elective CaesareanDelivery

Yes No

37%

63%

ART During LaborAZT and/or antiretrovirals

79%

21%

Perinatally Acquired HIV Infection Cases in Children Whose Mom’s HIV status was Known

Prior to Delivery Born in Florida, 2005-2012,by Receipt of Antiretroviral Therapy (ART) During Delivery and Elective Caesarean Delivery (N=57)

Page 37: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Maternal Drug AbuseHistory of an STDDuring Pregnancy

Yes34%

No66%

Note: A total of 9 (11%) of the mothers had BOTH abused drugs and had an STD during pregnancy.

Yes38%

No62%

Perinatally Acquired HIV Infection Cases in Children Born in Florida, 2005-2012,

by Maternal Drug Abuse and History of a Sexually Transmitted Disease (STD) (N=86)

Page 38: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Received any Neonatal ART Breastfed

No22%

Yes78%

Yes8%

No/Unkn92%

Perinatally Acquired HIV Infection Cases in Children Born in Florida, 2005-2012,

by Receipt of Neonatal Antiretroviral Therapy (ART) and Exposure to Breastfeeding (N=86)

Page 39: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

29%

42%

29%

94%

6%11%

83%

6%

Perinatally Acquired HIV Infection CasesBorn in Selected South Florida Counties,

2005-2012, by Mother’s Exposure Category (N=42)

Mom-IDU Risk Mom-Sex Risk Mom-Other Risk/Unknown

Miami-Dade (N=18) Broward (N=17) Palm Beach (N=7)

Note: A total of 42 (49% of the state total) perinatally acquired HIV Infection cases born in Florida 2005-2012were born in Miami-Dade, Broward and Palm Beach counties. There is some variation in the Mother’s exposure category by county.

Page 40: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

83%

11%6%

<1 year 1 year 2+ years

88%

0%12%

100%

0%0%

Perinatally Acquired HIV Infection CasesBorn in Selected South Florida Counties,

2005-2012, by Age at First Diagnosis (N=42)

Note: Eighty-eight percent (37 of 42) of the perinatally acquired HIV Infection cases born in South Florida were diagnosed within the first year of life. As noted earlier, an early diagnosis of perinatally acquired HIV infection allows the opportunity of early treatment, thus possibly prolonging the onset of AIDS.

Miami-Dade (N=18) Broward (N=17) Palm Beach (N=7)

Page 41: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

88%

6%

6%

83%

17%

White Black Hispanic Other/Unknown

Note: Pediatric AIDS in Florida disproportionately affects non-Hispanic blacks. In South Florida, 81%, (34 of 42) of the pediatric HIV/AIDS cases were among blacks.

Miami-Dade (N=18) Broward (N=17) Palm Beach (N=7)

57%

14%

29%

Perinatally Acquired HIV Infection CasesBorn in Selected South Florida Counties,

2005-2012, by Race/Ethnicity (N=42)

Page 42: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

HIV Status for Babies Bornto an HIV-Infected Mother

in Florida, 2007-2012

98.6%

1.4%

Exposed Only

HIV-Infected

# % # % # %Exposed 655 97.5% 617 98.1% 613 98.6%Infected 17 2.5% 12 1.9% 9 1.4%Total Births 672 629 622

2007 2008 2009 2012 Births

A total of 511 babies were known to be born to HIV-Infected mothers in Florida in 2012, of which 7 (1.4%) were known to be HIV-infected. (Data as of 08/29/2013)2012 data are incomplete due to reporting lags.Note: Perintal Exposure became reportable 11/20/2006, 2007 is the first complete year.

# % # % # %Exposed 570 99.0% 555 99.5% 504 98.6%Infected 6 1.0% 3 0.5% 7 1.4%Total Births 576 558 511

2010 2011 2012

Page 43: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

STEPS TO PERINATAL SUCCESS

Get an HIV TestGet Prenatal Care If HIV+, MaintainMedication Adherence

Keep All Prenatal Appointments

Follow Up for MomAnd Baby

Ensure Baby Gets6-weeks of AZT

Page 44: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

STEPS TO PERINATAL SUCCESS, CONTINUED

Link to Birth Control if thatIs the Client’s Choice

Ensure that BabyReceives HIV testing By 4 months

Counsel Against Breast Feeding

Page 45: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Perinatal Perinatal ProgramsPrograms

• Perinatal Prevention is focused on:

– Prevention Services for women of child bearing age.

– Ensuring services for HIV-infected pregnant women and their newborns

– Education and technical assistance for clinicians who treat pregnant women.

Page 46: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

The Targeted Outreach for Pregnant Women Act (TOPWA) program.

Collaboration with state agencies and organizations to ensure that perinatal HIV issues are addressed.

Perinatal social marketing campaign on Face Book and Twitter

The Perinatal HIV Program” is located on the HIV/AIDS and Hepatitis Program internet site

A Perinatal website through USF that is widely used

Provide 6-weeks of free AZT for newborns of families with no medical coverage

Page 47: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

The Baby RxPress Program provides a voucher that can be exchanged at Walgreens for the six-weeks of AZT that is prescribed for all HIV-exposed newborns.

Vouchers can be obtained from a local HIV perinatal nurse or the HIV/AIDS and Hepatitis Program Prevention Section.

Page 48: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

AETC staff work to:• Educate medical professionals who provide care

for HIV-infected pregnant women and their babies.

• Assist hospitals in implementing rapid HIV testing in labor & delivery units.

• Maintain a comprehensive website with CDC guidelines, forms, and resources for clinicians.

Source: http://www.usfcenter.org/Perinatal/

Page 49: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

8 programs (3 also have jail components).

Conducts outreach to high-risk pregnant women and actively links them with services.

Offers on-site pregnancy and HIV testing.

Assists mothers with obtaining family planning services if they choose to delay the birth of a subsequent baby.

For more information on TOPWA please see this webpage: http://www.preventhivflorida.org/Women_Children/TOPWA.htm

Page 50: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

HIV-Infected Newborns 2007-2012HIV-Infected Newborns 2007-2012

MADISON

TAYLOR

JEFFERSON

SANTA ROSAOKALOOSA

WALTON

HOLMES

JACKSON

WASHINGTON

CALHOUNBAY

GULF

GADSDEN

LIBERTY

FRANKLIN

LEON

WAKULLA

HAMILTON

SUWANNEE

LAFAYETTE

DIXIE

COLUMBIA

GILCHRIST

LEVY

ALACHUAPUTNAM

MARION

LAKECITRUS

SUMTER

HERNANDO

BAKER

NASSAU

DUVAL

CLAYST JOHNS

FLAGLER

VOLUSIA

SEMINOLE

ORANGEBREVARD

OSCEOLA

PASCO

HILLSBOROUGHPOLK

MANATEEHARDEE

HIGHLANDS

PINELLAS

UNION

INDIAN RIVER

OKEECHOBEEST LUCIE

MARTIN

PALM BEACH

BROWARD

DADE

MONROE

COLLIER

HENDRYLEE

CHARLOTTE GLADES

DESOTOSARASOTA

ESCAMBIA

2007 Births

Updated 8/27/2013

(17)

(12) 2008 Births

2009 Births(9)

(6) 2010 Births

2011 Births(3)

2012 Births(7)

Page 51: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

MADISON

TAYLOR

JEFFERSON

ESCAMBIA

SANTA ROSAOKALOOSA

WALTON

HOLMESJACKSON

WASHINGTON

CALHOUN

BAY

GULF

GADSDEN

LIBERTY

FRANKLIN

LEON

WAKULLA

HAMILTON

SUWANNEE

LAFAYETTE

DIXIE

CO

LU

MB

IA

GILCHRIST

LEVY

BRADFORD

ALACHUA

PUTNAM

MARION

LAKECITRUS

SUMTER

HERNANDO

BAKER

NASSAU

DUVAL

CLAY ST JOHNS

FLAGLER

VOLUSIA

SEMINOLE

ORANGEBREVARD

OSCEOLA

PASCO

HILLSBOROUGHPOLK

MANATEE

HARDEE

HIGHLANDS

PINELLAS

UNION

INDIAN RIVER

OKEECHOBEE

ST LUCIE

MARTIN

PALM BEACH

BROWARD

DADEMONROE

COLLIER

HENDRYLEE

CHARLOTTEGLADES

DESOTOSARASOTA

6

3

9

78

1

2

3

5412

2

2

1

5

29

2

4

7

2

3

100

2

3

36

1

55

3

13

9

2

2

1

14 9

1

1

2012

HIV-Exposed/Infected Babies

Updated 8/27/2013

1

2

7

1

1

2

2

1

1

1

9

13

Exposed/Not Infected: 511Infected: 7

Page 52: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

89

87

85

87

85

88

87

83

84

85

86

87

88

89

90

2008 2009 2010 2011Year

Pe

rce

nt

HIV Discussions HIV Testing

PRAMS: Healthcare Provider Discussions About HIV Testing, and Pregnant Women Tested for

HIV in Florida, 2008-2011*

Note: Overall, Florida’s percentage of childbearing women tested perinatally for HIV is among the highest in the U.S., which has probably contributed to the continued decline in pediatric HIV/AIDS cases. However, Florida’s HIV testing for pregnant women have decreased 3.5 percentage points from 2008 to 2011. Source: Florida Pregnancy Risk Assessment Monitoring System (PRAMS). *2011 data is the most recent available. http://www.doh.state.fl.us/disease_ctrl/epi/Chronic_Disease/PRAMS/Data_Books.htm

Page 53: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Prenatal HIV Testing Among Women Delivering a Live Birth,

2008-2011*, Florida

65

70

75

80

85

90

95

100

2008 2009 2010 2011

Year

Per

cen

t T

este

d

= 95% C.I.

Note: Overall, Florida’s percentage of childbearing women tested perinatally for HIV is among the highest in the U.S., which has probably contributed to the continued decline in pediatric HIV/AIDS cases. However, Florida’s HIV testing for pregnant women have decreased 3.8 percentage points from 2008 to 2011. Source: Florida Pregnancy Risk Assessment Monitoring System (PRAMS). (*2011 data is most recent available.)http://www.doh.state.fl.us/disease_ctrl/epi/Chronic_Disease/PRAMS/Data_Books.htm

Page 54: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

HIV Seroprevalence Among Childbearing Women by Survey Cycle and Mother’s

Race,1988-1995, Florida

0

5

10

15

20

1988 1989 1990 1992 1992 1993 1994 1995

Survey Cycle

Rat

e p

er 1

,000

White

Black

Total

*Number Positive/Number Tested x 1,000.Survey Cycles are October through March, except for the last cycle which was 10/95-12/95.This survey ended in 1995.

Page 55: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Cases of HIV Disease Among Women of Childbearing Age (Ages 15-44),

by Age of Diagnosis, and Year of Diagnosis, 2003–2012, Florida

0

100

200

300

400

500

600

700

800

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012Year of Diagnosis

Nu

mb

er o

f C

ases

15-24 25-29 30-39 40-44

Decreases in newly diagnosis HIV/AIDS cases among women ages 15-44 have been observed by all age groups.

Page 56: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

0

200

400

600

800

1,000

1,200

1,400

1,600

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Year of Diagnosis

Nu

mb

er

of

Ca

se

sCases of HIV Disease Among

Women of Childbearing Age (Ages 15-44), by Mode of Exposure,

and Year of Diagnosis, 2003–2012, Florida

Heterosexual

IDU

Note: NIRs redistributed.

Page 57: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Cases of HIV Disease Among Women of Childbearing Age (Ages 15-44),

by Race/Ethnicity, and Year of Diagnosis, 2003–2012, Florida

0

200

400

600

800

1,000

1,200

1,400

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Year of Diagnosis

Nu

mb

er o

f C

ases

Black

Hispanic

White

Note: Although the majority of HIV cases among women are black, the number of black female HIV cases has decreased 63% from 2003 to 2012. Likewise, the number of HIV cases decreased by 52% among white females and 58% among Hispanic females, over this same time period. *Other races represent less than 1% of the cases and are not included. Data as of 06/30/2013

Page 58: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

Annual Prevalence of HIV Disease Among Women of Childbearing Age (Ages 15-44),

by Race/Ethnicity, Reported 1995-2012, Florida

0

2,000

4,000

6,000

8,000

10,000

12,000

95 96 97 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12

Year of Diagnosis

Nu

mb

er

of

Cases

White Black Hispanic

Page 59: Epidemiology of  HIV Among Pediatric* Cases  in Florida, through 2012

For Florida HIV/AIDS Surveillance DataContact: (850) 245-4444

Lorene Maddox, MPH Ext. 2613 Tracina Bush, BSW Ext. 2612 Madgene Moise, MPH Ext. 2373

Visit Florida’s internet site for:Monthly Surveillance Reports

Slide Sets and Fact SheetsAnnual Reports and Epi Profiles

http://www.doh.state.fl.us/disease_ctrl/aids/trends/trends.html

Visit CDC’s HIV/AIDS internet site for:Surveillance Reports, fact sheets and slide sets

http://www.cdc.gov/hiv/topics/surveillance/resources/reports/index.htm