Enzyme flexibility, solvent and ‘weak’ interactions characterize thrombin–ligand interactions: implications for drug design 

Richard A Engh, Hans Brandstetter, Gudrun Sucher, Andreas Eichinger, Ulrich Baumann, Wolfram Bode, Robert Huber, Thomas Poll, Rainer Rudolph, Wolfgang von der Saal 

Structure Volume 4, Issue 11, Pages 1353-1362 (November 1996)

DOI: 10.1016/S0969-2126(96)00142-6

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Structure 1996 4, 1353-1362DOI: (10.1016/S0969-2126(96)00142-6)

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Structure 1996 4, 1353-1362DOI: (10.1016/S0969-2126(96)00142-6)

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Structure 1996 4, 1353-1362DOI: (10.1016/S0969-2126(96)00142-6)

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Structure 1996 4, 1353-1362DOI: (10.1016/S0969-2126(96)00142-6)

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Structure 1996 4, 1353-1362DOI: (10.1016/S0969-2126(96)00142-6)

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Structure 1996 4, 1353-1362DOI: (10.1016/S0969-2126(96)00142-6)

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Structure 1996 4, 1353-1362DOI: (10.1016/S0969-2126(96)00142-6)